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Conserved domains on  [gi|1958761181|ref|XP_008759941|]
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cip1-interacting zinc finger protein isoform X6 [Rattus norvegicus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 10648578)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 93-394 3.17e-08

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.64  E-value: 3.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181   93 AMPPATYDSASLTMPTAALGNLRAYNVTAPNLAA--PSLTPPQMvtpnlqqffPQATRQSLLGPPPVG-----IPINPSQ 165
Cdd:PHA03247  2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgpPAPAPPAA---------PAAGPPRRLTRPAVAslsesRESLPSP 2801

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  166 HNHSGRNSQKQPRTPSSTTPNHKTVPLDDREDPTEGSEEATELQMDTAEDQDSLVFPDG-LASEPQVHEPEPEPFEALEP 244
Cdd:PHA03247  2802 WDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGdVRRRPPSRSPAAKPAAPARP 2881

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  245 PAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVlQIQTLSKLQKQAQTQTSPEHL 324
Cdd:PHA03247  2882 PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP-QPPLAPTTDPAGAGEPSGAVP 2960

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  325 APQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPAcatepqLLSNAAEVGRDpEETLPEPVS 394
Cdd:PHA03247  2961 QPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR------VSSWASSLALH-EETDPPPVS 3023
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 570-594 1.71e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


:

Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.71e-05
                          10        20
                  ....*....|....*....|....*
gi 1958761181 570 FCTICNRYFKTPRKFVEHVKSQGHK 594
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 476-508 1.67e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 1.67e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1958761181  476 QFFCYICKASCSSQQEFQDHMSEAQHQQRLGEM 508
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 684-717 3.63e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 3.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1958761181  684 GYVCRICHKFYDSNSEFRlSHCKSLAHFENLQKY 717
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 93-394 3.17e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.64  E-value: 3.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181   93 AMPPATYDSASLTMPTAALGNLRAYNVTAPNLAA--PSLTPPQMvtpnlqqffPQATRQSLLGPPPVG-----IPINPSQ 165
Cdd:PHA03247  2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgpPAPAPPAA---------PAAGPPRRLTRPAVAslsesRESLPSP 2801

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  166 HNHSGRNSQKQPRTPSSTTPNHKTVPLDDREDPTEGSEEATELQMDTAEDQDSLVFPDG-LASEPQVHEPEPEPFEALEP 244
Cdd:PHA03247  2802 WDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGdVRRRPPSRSPAAKPAAPARP 2881

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  245 PAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVlQIQTLSKLQKQAQTQTSPEHL 324
Cdd:PHA03247  2882 PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP-QPPLAPTTDPAGAGEPSGAVP 2960

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  325 APQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPAcatepqLLSNAAEVGRDpEETLPEPVS 394
Cdd:PHA03247  2961 QPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR------VSSWASSLALH-EETDPPPVS 3023
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 570-594 1.71e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.71e-05
                          10        20
                  ....*....|....*....|....*
gi 1958761181 570 FCTICNRYFKTPRKFVEHVKSQGHK 594
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
ftsN TIGR02223
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ...
 225-371 1.63e-04

cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]


Pssm-ID: 274041 [Multi-domain]  Cd Length: 298  Bit Score: 44.30  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 225 LASEPQVHEPEPEPFEALEPpakRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQ----LPEPPEALVVPRIQP 300
Cdd:TIGR02223  75 LPPKPEERWSYIEELEAREV---LINDPEEPSNGGGVEESAQLTAEQRQLLEQMQADMRAAekvlATAPSEQTVAVEARK 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958761181 301 QVlqIQTLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKT-QDQPQTWPQGSAPPPEQASVPACATE 371
Cdd:TIGR02223 152 QT--AEKKPQKARTAEAQKTPVETEKIASKVKEAKQKQKALPKQTaETQSNSKPIETAPKADKADKTKPKPK 221
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 476-508 1.67e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 1.67e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1958761181  476 QFFCYICKASCSSQQEFQDHMSEAQHQQRLGEM 508
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 684-717 3.63e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 3.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1958761181  684 GYVCRICHKFYDSNSEFRlSHCKSLAHFENLQKY 717
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 476-502 3.97e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.22  E-value: 3.97e-03
                          10        20
                  ....*....|....*....|....*..
gi 1958761181 476 QFFCYICKASCSSQQEFQDHMSEAQHQ 502
Cdd:pfam12171   1 QFYCVLCDKYFKSENALQNHLKSKKHK 27
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 148-392 8.63e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 39.63  E-value: 8.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 148 RQSLLGPPPVGIPINPSQHNhsgrnSQKQPRTPSSTTPNHKTVPLDDREDPTEGSEEATELQMDTaedqdSL--VFPDGL 225
Cdd:pfam09770 101 RFNRQQPAARAAQSSAQPPA-----SSLPQYQYASQQSQQPSKPVRTGYEKYKEPEPIPDLQVDA-----SLwgVAPKKA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 226 ASEPQVHEPEPEPfEALEPPAKRLRSSEEstekgptgqpqarVQPQTQMTAPKQTQtpdqlPEPPEALVVPRIQPQvlqi 305
Cdd:pfam09770 171 AAPAPAPQPAAQP-ASLPAPSRKMMSLEE-------------VEAAMRAQAKKPAQ-----QPAPAPAQPPAAPPA---- 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 306 qtlsklQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPACAtePQLLSNAAEVGRDP 385
Cdd:pfam09770 228 ------QQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQA--QQFHQQPPPVPVQP 299


                  ....*..
gi 1958761181 386 EETLPEP 392
Cdd:pfam09770 300 TQILQNP 306
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 93-394 3.17e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.64  E-value: 3.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181   93 AMPPATYDSASLTMPTAALGNLRAYNVTAPNLAA--PSLTPPQMvtpnlqqffPQATRQSLLGPPPVG-----IPINPSQ 165
Cdd:PHA03247  2731 ASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgpPAPAPPAA---------PAAGPPRRLTRPAVAslsesRESLPSP 2801

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  166 HNHSGRNSQKQPRTPSSTTPNHKTVPLDDREDPTEGSEEATELQMDTAEDQDSLVFPDG-LASEPQVHEPEPEPFEALEP 244
Cdd:PHA03247  2802 WDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGdVRRRPPSRSPAAKPAAPARP 2881

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  245 PAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVlQIQTLSKLQKQAQTQTSPEHL 324
Cdd:PHA03247  2882 PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP-QPPLAPTTDPAGAGEPSGAVP 2960

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  325 APQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPAcatepqLLSNAAEVGRDpEETLPEPVS 394
Cdd:PHA03247  2961 QPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR------VSSWASSLALH-EETDPPPVS 3023
PHA03247 PHA03247
large tegument protein UL36; Provisional
 95-407 2.70e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.56  E-value: 2.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181   95 PPATYDSASLTMPTAALGNLRAYNVTAPNLAAPSLTPPQMVTPNlqqffPQATRQSLLGPPPVGIPINPSqhNHSGRNSQ 174
Cdd:PHA03247  2712 PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPA-----RPARPPTTAGPPAPAPPAAPA--AGPPRRLT 2784

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  175 KQPRTPSSTTPNHKTVPLDDREDPTEGSEEATELqmdTAEDQDSLVFPDGLASEPQVHEPEPEPFEALEPPAKRLRSSEE 254
Cdd:PHA03247  2785 RPAVASLSESRESLPSPWDPADPPAAVLAPAAAL---PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGD 2861

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  255 STEKGPTGQPQARvqPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQvlqiqtlsklqkqaqTQTSPEHLAPQQNQVSTQ 334
Cdd:PHA03247  2862 VRRRPPSRSPAAK--PAAPARPPVRRLARPAVSRSTESFALPPDQPE---------------RPPQPQAPPPPQPQPQPP 2924

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958761181  335 AQPQEQTSEKTQDQPQtwpqgsaPPPEQASVPACATEPQLLSNAAEVGRDPEETLPEPVSAQSSEDRSQEPSA 407
Cdd:PHA03247  2925 PPPQPQPPPPPPPRPQ-------PPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990
PHA03247 PHA03247
large tegument protein UL36; Provisional
 109-475 7.08e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 7.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  109 AALGNLRAYNVTAPNLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPPPVGIPINPSQHNHSGRNSQKQPRTPSSTTPNHK 188
Cdd:PHA03247  2690 PTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAP 2769

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  189 TVPlddrEDPTEGSEEATElqmdtaedqdslvfPDGLASEPQVHEPEPEPFEALEPPAKRLRSSEESTekgPTGQPQARV 268
Cdd:PHA03247  2770 APP----AAPAAGPPRRLT--------------RPAVASLSESRESLPSPWDPADPPAAVLAPAAALP---PAASPAGPL 2828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  269 QPQT--QMTAPKQTQTPDQLPEPPEALVVPRiqpqvlqiqtlSKLQKQAQTQTSPEHLA-PQQNQVSTQAQPQEQTSekT 345
Cdd:PHA03247  2829 PPPTsaQPTAPPPPPGPPPPSLPLGGSVAPG-----------GDVRRRPPSRSPAAKPAaPARPPVRRLARPAVSRS--T 2895

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  346 QDQPQtwPQGSAPPPEQASVPACATEPQllsnaaevgrdPEETLPEPVSAQSSEDRSQEPSAGGLDVGECEKRAGEVLGM 425
Cdd:PHA03247  2896 ESFAL--PPDQPERPPQPQAPPPPQPQP-----------QPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQP 2962

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958761181  426 W-GAGSSLKVTILQSSNSRAFNTTPLTSGPRPGDSASATPALASTPSKQSL 475
Cdd:PHA03247  2963 WlGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLAL 3013
PRK10927 PRK10927
cell division protein FtsN;
234-401 8.50e-06

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 48.52  E-value: 8.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 234 PEPEP----FEALEPPAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQT---QTPDQLPEPPEALVVPRIQPQVLQIQ 306
Cdd:PRK10927   77 PKPEErwryIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQAdmrQQPTQLVEVPWNEQTPEQRQQTLQRQ 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 307 ----TLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKTQDQPQTwpqgsaPPPEQASVPACATEPQLLSNAAEVG 382
Cdd:PRK10927  157 rqaqQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQ------PYQDLLQTPAHTTAQSKPQQAAPVT 230

                         170
                  ....*....|....*....
gi 1958761181 383 RDPEEtlPEPVSAQSSEDR 401
Cdd:PRK10927  231 RAADA--PKPTAEKKDERR 247
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 570-594 1.71e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.71e-05
                          10        20
                  ....*....|....*....|....*
gi 1958761181 570 FCTICNRYFKTPRKFVEHVKSQGHK 594
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 225-399 1.48e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 45.24  E-value: 1.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 225 LASEPQVHEPEPE-PFEALEPPAkrlrsseestEKGPTGQPQARVQPQTQMTAPKQ-TQTPDQLPEPPEALVVPRI---Q 299
Cdd:PRK07994  357 LAFHPAAPLPEPEvPPQSAAPAA----------SAQATAAPTAAVAPPQAPAVPPPpASAPQQAPAVPLPETTSQLlaaR 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 300 PQVLQIQTLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPacATEPQLLSNAA 379
Cdd:PRK07994  427 QQLQRAQGATKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEP--VATPKALKKAL 504

                         170       180
                  ....*....|....*....|
gi 1958761181 380 EVGRDPEetLPEPVSAQSSE 399
Cdd:PRK07994  505 EHEKTPE--LAAKLAAEAIE 522
ftsN TIGR02223
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ...
 225-371 1.63e-04

cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]


Pssm-ID: 274041 [Multi-domain]  Cd Length: 298  Bit Score: 44.30  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 225 LASEPQVHEPEPEPFEALEPpakRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQ----LPEPPEALVVPRIQP 300
Cdd:TIGR02223  75 LPPKPEERWSYIEELEAREV---LINDPEEPSNGGGVEESAQLTAEQRQLLEQMQADMRAAekvlATAPSEQTVAVEARK 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958761181 301 QVlqIQTLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKT-QDQPQTWPQGSAPPPEQASVPACATE 371
Cdd:TIGR02223 152 QT--AEKKPQKARTAEAQKTPVETEKIASKVKEAKQKQKALPKQTaETQSNSKPIETAPKADKADKTKPKPK 221
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 476-508 1.67e-04

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 1.67e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1958761181  476 QFFCYICKASCSSQQEFQDHMSEAQHQQRLGEM 508
Cdd:smart00451   3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 282-406 2.39e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 44.69  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  282 TPDQLPEP-PEALVVPRIQPQVLQiQTLSKLQKQAQTQTSpehLAPQQNQVSTQaQPQEQTSEKTQDQPQTWPQGSAPPP 360
Cdd:PRK10263   746 TPIVEPVQqPQQPVAPQQQYQQPQ-QPVAPQPQYQQPQQP---VAPQPQYQQPQ-QPVAPQPQYQQPQQPVAPQPQYQQP 820

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1958761181  361 EQASVPacatEPQLLSNAAEVGRDPEETLPEPVSAQSSEDRS-QEPS 406
Cdd:PRK10263   821 QQPVAP----QPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPlHKPT 863
PRK12757 PRK12757
cell division protein FtsN; Provisional
 260-360 3.98e-04

cell division protein FtsN; Provisional


Pssm-ID: 237191 [Multi-domain]  Cd Length: 256  Bit Score: 43.11  E-value: 3.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 260 PTGQPQARVQPQ---------TQMTAPKQtQTPDQLPEPPEALVVPRIQPQVLQIQTLSKLQKQAQTQTSPEHLAPQQnq 330
Cdd:PRK12757   68 PSAGGEVNSPTQltdeqrqllEQMQADMR-QQPTQLSEVPYNEQTPQVPRSTVQIQQQAQQQQPPATTAQPQPVTPPR-- 144

                          90       100       110
                  ....*....|....*....|....*....|
gi 1958761181 331 vsTQAQPQEQTSEKTQDQPQTWPQGSAPPP 360
Cdd:PRK12757  145 --QTTAPVQPQTPAPVRTQPAAPVTQAVEA 172
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 263-372 5.68e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.54  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  263 QPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPriQPQVLQIQTLSKLQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTS 342
Cdd:PRK10263   767 QPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAP--QPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDT 844

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1958761181  343 -------EKTQDQPQTWPQGSAPPPEQASVPACATEP 372
Cdd:PRK10263   845 llhpllmRNGDSRPLHKPTTPLPSLDLLTPPPSEVEP 881
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 229-361 2.05e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.99  E-value: 2.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  229 PQVHEPEPEPFEALE--PPAKRLRSSEESTEKgPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVLQIQ 306
Cdd:PRK10263   364 PGPQTGEPVIAPAPEgyPQQSQYAQPAVQYNE-PLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPV 442

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958761181  307 TLSKLQKQAQTQtspeHLAPQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPE 361
Cdd:PRK10263   443 AGNAWQAEEQQS----TFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPE 493
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 684-717 3.63e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 3.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1958761181  684 GYVCRICHKFYDSNSEFRlSHCKSLAHFENLQKY 717
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 213-403 3.80e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.84  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  213 AEDQDSLVFPDGLASEPQVHEPEP--------EPFEALEPPAKRLRSSEESTEkgPTGQPQARVQPQTQMTAPKQTQTPD 284
Cdd:PRK10263   286 AADPDDVLFSGNRATQPEYDEYDPllngapitEPVAVAAAATTATQSWAAPVE--PVTQTPPVASVDVPPAQPTVAWQPV 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181  285 QLPEPPEALVVPRI-----QPQVLQIQTLSKLQKQAQTQTSPEHLAPQQNQVStQAQPQEQTSEKTQDQPQTWPQGSAPP 359
Cdd:PRK10263   364 PGPQTGEPVIAPAPegypqQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPA-QQPYYAPAPEQPAQQPYYAPAPEQPV 442

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1958761181  360 PEQASVPacatEPQLLSNAAEVGRDPEETLPEPVSAQSSEDRSQ 403
Cdd:PRK10263   443 AGNAWQA----EEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQ 482
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 476-502 3.97e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.22  E-value: 3.97e-03
                          10        20
                  ....*....|....*....|....*..
gi 1958761181 476 QFFCYICKASCSSQQEFQDHMSEAQHQ 502
Cdd:pfam12171   1 QFYCVLCDKYFKSENALQNHLKSKKHK 27
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 229-358 5.43e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 40.48  E-value: 5.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 229 PQVHEPEPEPFEALEPPAKRLRSSEESTEKGPT----GQPQARVQPQTQMTAPKQTQTPDQLP--EPPEALVVPRIQPQV 302
Cdd:PRK14949  649 PSRAPPASLSKPASSPDASQTSASFDLDPDFELathqSVPEAALASGSAPAPPPVPDPYDRPPweEAPEVASANDGPNNA 728

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958761181 303 LQIQTLSKLQKQAQTQTSPEHLAPQQnQVSTQAQPQEQTSEKTQDQPQTWPQGSAP 358
Cdd:PRK14949  729 AEGNLSESVEDASNSELQAVEQQATH-QPQVQAEAQSPASTTALTQTSSEVQDTEL 783
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 222-412 6.32e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 6.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 222 PDGLASEPQVHEPEPEPFEALEPPAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQ 301
Cdd:PRK07764  629 PAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT 708

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 302 vlqiqtlsklqKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPACATEPQLLSNAAEV 381
Cdd:PRK07764  709 -----------PPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPS 777

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1958761181 382 GRD-PEETLPEPVSAQSSEDRsQEPSAGGLDV 412
Cdd:PRK07764  778 PPSeEEEMAEDDAPSMDDEDR-RDAEEVAMEL 808
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 148-392 8.63e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 39.63  E-value: 8.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 148 RQSLLGPPPVGIPINPSQHNhsgrnSQKQPRTPSSTTPNHKTVPLDDREDPTEGSEEATELQMDTaedqdSL--VFPDGL 225
Cdd:pfam09770 101 RFNRQQPAARAAQSSAQPPA-----SSLPQYQYASQQSQQPSKPVRTGYEKYKEPEPIPDLQVDA-----SLwgVAPKKA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 226 ASEPQVHEPEPEPfEALEPPAKRLRSSEEstekgptgqpqarVQPQTQMTAPKQTQtpdqlPEPPEALVVPRIQPQvlqi 305
Cdd:pfam09770 171 AAPAPAPQPAAQP-ASLPAPSRKMMSLEE-------------VEAAMRAQAKKPAQ-----QPAPAPAQPPAAPPA---- 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761181 306 qtlsklQKQAQTQTSPEHLAPQQNQVSTQAQPQEQTSEKTQDQPQTWPQGSAPPPEQASVPACAtePQLLSNAAEVGRDP 385
Cdd:pfam09770 228 ------QQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQA--QQFHQQPPPVPVQP 299


                  ....*..
gi 1958761181 386 EETLPEP 392
Cdd:pfam09770 300 TQILQNP 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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