|
Name |
Accession |
Description |
Interval |
E-value |
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
567-1566 |
0e+00 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 1219.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 567 GKHSMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNT 646
Cdd:pfam03154 1 GKHSMRTRRSRGSMSTLRSGRKKQTASPDGRASPTNEDLRSSGRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 647 KRQREKVASDTEDTDRATSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 726
Cdd:pfam03154 81 KRQREKGASDTEEPERATAKKSKTQEISRPNSPSEGEGESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 727 SAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPaaHTLIQQTPTLH 806
Cdd:pfam03154 161 SAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAP--HTLIQQTPTLH 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 807 PPRLPSPHPPLQPMT--APPSQNSAQPHPQPSLHGQGPPGPHSLQTGP-LLQHPGPPQPFGLTPQSSQGQGPLGPSPAAA 883
Cdd:pfam03154 239 PQRLPSPHPPLQPMTqpPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPsHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 884 HP-HSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 962
Cdd:pfam03154 319 GQsQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 963 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGGLHQVPSQSPFPQHPFVPGGPPPITPP 1042
Cdd:pfam03154 399 LSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPP 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1043 SCPPTSTPPAGPSSSSQPPcsAAVSSGGNVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQS 1122
Cdd:pfam03154 479 SGPPTSTSSAMPGIQPPSS--ASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPSHASQS 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1123 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAqKAS 1202
Cdd:pfam03154 557 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEKEREREREREREAERAA-KAS 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1203 SSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM 1282
Cdd:pfam03154 636 SSSHEGRMGDPQLAGPAHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFFVPLNPTDPLLAYHM 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1283 PGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHP 1362
Cdd:pfam03154 716 PGLYNVDPAIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHGALTLPPMAGPHPFASFHP 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1363 GLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSA 1442
Cdd:pfam03154 796 GLNPLERERLALAGPQLRPEMSYPDRLAAERLHAERMASLTNDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSG 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1443 GPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFaepvlrlaGTPYPRDLPGAIPPPMSAAHQLQAMH 1522
Cdd:pfam03154 876 GPVHPLVDPLAAGPHLARFPYPPGAIPNPLLGQPPHEHEMLRHPVF--------GTPYPRDLPGGLPPPMSAAHQLQAMH 947
|
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 672054330 1523 AQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQ 1566
Cdd:pfam03154 948 AQSAELQRLAMEQQWLHGHPHMHGGHLPGQEDYYSRLKKESDKQ 991
|
|
| BAH_MTA |
cd04709 |
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The ... |
101-306 |
2.69e-81 |
|
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
Pssm-ID: 240060 Cd Length: 164 Bit Score: 264.25 E-value: 2.69e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 101 DVVYRPGDCVYIESRrPNTPYFICSIQDFKLvhnsqaccrspapalcdppacslpvasqppqhlseagrgpvgSKRDHLL 180
Cdd:cd04709 1 ANMYRVGDYVYFESS-PNNPYLIRRIEELNK------------------------------------------TARGHVE 37
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 181 MNVKWYYRQSEVPDSVYQHLVQDRHNEND-SGRELVITDPVIKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFK 259
Cdd:cd04709 38 AKVVCYYRRRDIPDSLYQLADQHRRELEEkSDDLTPKQRHQLRHRELFLSRQVETLPATHIRGKCSVTLLNDTESARSYL 117
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 672054330 260 ARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDG 306
Cdd:cd04709 118 AREDTFFYSLVYDPEQKTLLADQGEIRVGPSYQAKLPDLQPFPSPDG 164
|
|
| SANT_MTA3_like |
cd11661 |
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ... |
394-439 |
4.33e-23 |
|
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.
Pssm-ID: 212559 [Multi-domain] Cd Length: 46 Bit Score: 93.45 E-value: 4.33e-23
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 672054330 394 CWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKK 439
Cdd:cd11661 1 EWSESEAKLFEEGLRKYGKDFHDIRQDFLPWKSVGELVEFYYMWKK 46
|
|
| ZnF_GATA |
smart00401 |
zinc finger binding to DNA consensus sequence [AT]GATA[AG]; |
502-551 |
2.72e-15 |
|
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
Pssm-ID: 214648 [Multi-domain] Cd Length: 52 Bit Score: 71.30 E-value: 2.72e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 672054330 502 KGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGEL-PPIEKPVDPP 551
Cdd:smart00401 2 SGRSCSNCGTTETPLWRRGPSGNKTLCNACGLYYKKHGGLkRPLSLKKDGI 52
|
|
| ZnF_GATA |
cd00202 |
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ... |
505-559 |
3.29e-15 |
|
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
Pssm-ID: 238123 [Multi-domain] Cd Length: 54 Bit Score: 71.25 E-value: 3.29e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 672054330 505 ACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPvDPPPFMFKPVK 559
Cdd:cd00202 1 ACSNCGTTTTPLWRRGPSGGSTLCNACGLYWKKHGVMRPLSKR-KKDQIKRRNRK 54
|
|
| ELM2 |
pfam01448 |
ELM2 domain; The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown ... |
285-335 |
1.54e-12 |
|
ELM2 domain; The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex. The domain is usually found to the N terminus of a myb-like DNA binding domain pfam00249. ELM2 is also found associated with an ARID DNA binding domain pfam01388 in Swiss:O82364. This suggests that ELM2 may also be involved in DNA binding, or perhaps is a protein-protein interaction domain.
Pssm-ID: 460214 Cd Length: 53 Bit Score: 63.40 E-value: 1.54e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 672054330 285 IRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMP--GVSDCDLLMYLRAARS 335
Cdd:pfam01448 1 IRVGPRYQAEIPELLPPSEEEDRYEEEDELLVWDPnhNLPDRKLDEYLVVARS 53
|
|
| GATA |
pfam00320 |
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ... |
506-541 |
1.25e-11 |
|
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.
Pssm-ID: 425605 [Multi-domain] Cd Length: 36 Bit Score: 60.41 E-value: 1.25e-11
10 20 30
....*....|....*....|....*....|....*.
gi 672054330 506 CRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGEL 541
Cdd:pfam00320 1 CSNCGTTKTPLWRRGPNGNRTLCNACGLYYKKKGLK 36
|
|
| BAH |
pfam01426 |
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ... |
102-280 |
6.30e-10 |
|
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.
Pssm-ID: 460207 Cd Length: 120 Bit Score: 58.47 E-value: 6.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 102 VVYRPGDCVYIESRRPNTPYFICSIQDFKlvhnsqaccrspapalCDPPACSLPVasqppqhlseagrgpvgskrdhllm 181
Cdd:pfam01426 1 ETYSVGDFVLVEPDDADEPYYVARIEELF----------------EDTKNGKKMV------------------------- 39
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 182 NVKWYYRQSEVPdsvyqHLVQDRHNEndsgrelvitdpviknRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFK-A 260
Cdd:pfam01426 40 RVQWFYRPEETV-----HRAGKAFNK----------------DELFLSDEEDDVPLSAIIGKCSVLHKSDLESLDPYKiK 98
|
170 180
....*....|....*....|
gi 672054330 261 RVDSFFYILGYNPETRRLNS 280
Cdd:pfam01426 99 EPDDFFCELLYDPKTKSFKK 118
|
|
| BAH |
smart00439 |
Bromo adjacent homology domain; |
104-280 |
1.55e-09 |
|
Bromo adjacent homology domain;
Pssm-ID: 214664 [Multi-domain] Cd Length: 121 Bit Score: 57.30 E-value: 1.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 104 YRPGDCVYIESRRPNTPYFICSIQDfklvhnsqaccrspapaLCDPPACSLPVASQppqhlseagrgpvgskrdhllmnV 183
Cdd:smart00439 2 ISVGDFVLVEPDDADEPYYIGRIEE-----------------IFETKKNSESKMVR-----------------------V 41
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 184 KWYYRQSEVPdsvyqHLVQDRHNENdsgrelvitdpviknrELFISDYVDTYHAAALRGKCNISHFSDIF--AAREFKAR 261
Cdd:smart00439 42 RWFYRPEETV-----LEKAALFDKN----------------EVFLSDEYDTVPLSDIIGKCNVLYKSDYPglRPEGSIGE 100
|
170
....*....|....*....
gi 672054330 262 VDSFFYILGYNPETRRLNS 280
Cdd:smart00439 101 PDVFFCESAYDPEKGSFKK 119
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
544-728 |
3.48e-08 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 58.38 E-value: 3.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 544 IEKPVDPP----PFMFKPVKEEDDGL----SGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSA 615
Cdd:NF033609 539 IDKPVVPEqpdePGEIEPIPEDSDSDpgsdSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDS 618
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 616 ASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE-DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVN 693
Cdd:NF033609 619 ASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDS 698
|
170 180 190
....*....|....*....|....*....|....*
gi 672054330 694 DEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 728
Cdd:NF033609 699 DSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 732
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
539-1028 |
3.94e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.80 E-value: 3.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 539 GELPPIEKPVDPPPFMFKPVKEeddglsgkhSMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNE--DVRSSGRNSPSAA 616
Cdd:PHA03247 2549 GDPPPPLPPAAPPAAPDRSVPP---------PRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDrgDPRGPAPPSPLPP 2619
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 617 STSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTEDTDRATSKKTKTqeiSRPNSPSEGEGESSDSRSVNDEG 696
Cdd:PHA03247 2620 DTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA---AQASSPPQRPRRRAARPTVGSLT 2696
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 697 SS-----DPKDIDQDNRSTSPSIPSPqdnesdsdsSAQQQMLQTQPPALQAPSGAASAPSTAPPGTtqlPTPGPTPSATT 771
Cdd:PHA03247 2697 SLadpppPPPTPEPAPHALVSATPLP---------PGPAAARQASPALPAAPAPPAVPAGPATPGG---PARPARPPTTA 2764
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 772 VPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPslhgqgPPGPHSLQTG 851
Cdd:PHA03247 2765 GPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL------PPPTSAQPTA 2838
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 852 PllqhPGPPQPFGLTPQSSQGQGPLGPSPAAAHPHSTIQLPASQSalqpqqppreqplppaplampHIKPPPTTPIPQLP 931
Cdd:PHA03247 2839 P----PPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPA---------------------RPPVRRLARPAVSR 2893
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 932 APQAHKHPPHLSGPSPfsmnanlppppalkPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASH 1011
Cdd:PHA03247 2894 STESFALPPDQPERPP--------------QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
|
490
....*....|....*..
gi 672054330 1012 PTTGGLHQVPSQSPFPQ 1028
Cdd:PHA03247 2960 PQPWLGALVPGRVAVPR 2976
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-728 |
2.80e-05 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 49.14 E-value: 2.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE 658
Cdd:NF033609 618 SASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 697
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672054330 659 -DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 728
Cdd:NF033609 698 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 768
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
395-440 |
3.89e-05 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 42.60 E-value: 3.89e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 672054330 395 WTEDEVKRFVKGLRQYG-KNFFRIRKElLPNKETGELITFYYYWKKT 440
Cdd:smart00717 4 WTEEEDELLIELVKKYGkNNWEKIAKE-LPGRTAEQCRERWRNLLKP 49
|
|
| Myb_DNA-binding |
pfam00249 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
395-438 |
1.04e-04 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 40.95 E-value: 1.04e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 672054330 395 WTEDEVKRFVKGLRQYGKNFFRIrKELLPNKETGELITFYYYWK 438
Cdd:pfam00249 4 WTPEEDELLLEAVEKLGNRWKKI-AKLLPGRTDNQCKNRWQNYL 46
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-778 |
4.61e-04 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.90 E-value: 4.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE 658
Cdd:NF033609 684 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 659 -DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSpsipspqDNESDSDSSAQQQMLQTQ 736
Cdd:NF033609 764 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDS-------DSDSDSDSDSDSDSDSDS 836
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 672054330 737 PPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSP 778
Cdd:NF033609 837 DSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPPNSP 878
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
643-792 |
6.30e-04 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 44.12 E-value: 6.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 643 LKNTKRQREKVASDTEDTDRATSKKTKtQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDN---------RSTSPS 713
Cdd:TIGR00601 5 FKTLQQQKFKIDMEPDETVKELKEKIE-AEQGKDAYPVAQQKLIYSGKILSDDKTVKEYKIKEKDfvvvmvskpKTGTGK 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672054330 714 IPSPqdnESDSDSSAQqqmlqtqpPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVA 792
Cdd:TIGR00601 84 VAPP---AATPTSAPT--------PTPSPPASPASGMSAAPASAVEEKSPSEESATATAPESPSTSVPSSGSDAASTLV 151
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-784 |
6.31e-04 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.51 E-value: 6.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTe 658
Cdd:NF033609 690 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS- 768
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 659 DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPS-IPSPQDNESDSDSSAQQQMLQTQ 736
Cdd:NF033609 769 DSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDS 848
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 672054330 737 PPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPP 784
Cdd:NF033609 849 DSDSDSDSESDSNSDSESGSNNNVVPPNSPKNGTNASNKNEAKDSKEP 896
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-728 |
8.85e-04 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.13 E-value: 8.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE 658
Cdd:NF033609 630 SASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 709
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672054330 659 -----DTDRATSKKTKTQEISRPNSPSEGEGES---SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 728
Cdd:NF033609 710 sdsdsDSDSDSDSDSDSDSDSDSDSDSDSDSDSdsdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 786
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-728 |
1.11e-03 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 43.74 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE 658
Cdd:NF033609 648 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 727
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672054330 659 -----DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 728
Cdd:NF033609 728 sdsdsDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 802
|
|
| COG5644 |
COG5644 |
U3 small nucleolar RNA-associated protein 14 [Function unknown]; |
642-747 |
7.48e-03 |
|
U3 small nucleolar RNA-associated protein 14 [Function unknown];
Pssm-ID: 227931 [Multi-domain] Cd Length: 869 Bit Score: 40.84 E-value: 7.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 642 PLKNTKRQREKVASDTEDTDRATSKKTKTQeiSRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSP--SIPSPQD 719
Cdd:COG5644 126 DLDTLLDNDQPEKNESGNNDHATDKENLLE--SDASSSNDSESEESDSESEIESSDSDHDDENSDSKLDNLrnYIVSLKK 203
|
90 100 110
....*....|....*....|....*....|....
gi 672054330 720 NESDS------DSSAQQQMLQTQPPALQAPSGAA 747
Cdd:COG5644 204 DEADAesvlssDDNDSIEEIKYDPHETNKESGSS 237
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
567-1566 |
0e+00 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 1219.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 567 GKHSMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNT 646
Cdd:pfam03154 1 GKHSMRTRRSRGSMSTLRSGRKKQTASPDGRASPTNEDLRSSGRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 647 KRQREKVASDTEDTDRATSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 726
Cdd:pfam03154 81 KRQREKGASDTEEPERATAKKSKTQEISRPNSPSEGEGESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 727 SAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPaaHTLIQQTPTLH 806
Cdd:pfam03154 161 SAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAP--HTLIQQTPTLH 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 807 PPRLPSPHPPLQPMT--APPSQNSAQPHPQPSLHGQGPPGPHSLQTGP-LLQHPGPPQPFGLTPQSSQGQGPLGPSPAAA 883
Cdd:pfam03154 239 PQRLPSPHPPLQPMTqpPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPsHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 884 HP-HSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 962
Cdd:pfam03154 319 GQsQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 963 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGGLHQVPSQSPFPQHPFVPGGPPPITPP 1042
Cdd:pfam03154 399 LSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPP 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1043 SCPPTSTPPAGPSSSSQPPcsAAVSSGGNVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQS 1122
Cdd:pfam03154 479 SGPPTSTSSAMPGIQPPSS--ASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPSHASQS 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1123 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAqKAS 1202
Cdd:pfam03154 557 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEKEREREREREREAERAA-KAS 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1203 SSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM 1282
Cdd:pfam03154 636 SSSHEGRMGDPQLAGPAHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFFVPLNPTDPLLAYHM 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1283 PGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHP 1362
Cdd:pfam03154 716 PGLYNVDPAIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHGALTLPPMAGPHPFASFHP 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1363 GLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSA 1442
Cdd:pfam03154 796 GLNPLERERLALAGPQLRPEMSYPDRLAAERLHAERMASLTNDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSG 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1443 GPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFaepvlrlaGTPYPRDLPGAIPPPMSAAHQLQAMH 1522
Cdd:pfam03154 876 GPVHPLVDPLAAGPHLARFPYPPGAIPNPLLGQPPHEHEMLRHPVF--------GTPYPRDLPGGLPPPMSAAHQLQAMH 947
|
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 672054330 1523 AQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQ 1566
Cdd:pfam03154 948 AQSAELQRLAMEQQWLHGHPHMHGGHLPGQEDYYSRLKKESDKQ 991
|
|
| BAH_MTA |
cd04709 |
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The ... |
101-306 |
2.69e-81 |
|
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
Pssm-ID: 240060 Cd Length: 164 Bit Score: 264.25 E-value: 2.69e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 101 DVVYRPGDCVYIESRrPNTPYFICSIQDFKLvhnsqaccrspapalcdppacslpvasqppqhlseagrgpvgSKRDHLL 180
Cdd:cd04709 1 ANMYRVGDYVYFESS-PNNPYLIRRIEELNK------------------------------------------TARGHVE 37
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 181 MNVKWYYRQSEVPDSVYQHLVQDRHNEND-SGRELVITDPVIKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFK 259
Cdd:cd04709 38 AKVVCYYRRRDIPDSLYQLADQHRRELEEkSDDLTPKQRHQLRHRELFLSRQVETLPATHIRGKCSVTLLNDTESARSYL 117
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 672054330 260 ARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDG 306
Cdd:cd04709 118 AREDTFFYSLVYDPEQKTLLADQGEIRVGPSYQAKLPDLQPFPSPDG 164
|
|
| SANT_MTA3_like |
cd11661 |
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ... |
394-439 |
4.33e-23 |
|
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.
Pssm-ID: 212559 [Multi-domain] Cd Length: 46 Bit Score: 93.45 E-value: 4.33e-23
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 672054330 394 CWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKK 439
Cdd:cd11661 1 EWSESEAKLFEEGLRKYGKDFHDIRQDFLPWKSVGELVEFYYMWKK 46
|
|
| ZnF_GATA |
smart00401 |
zinc finger binding to DNA consensus sequence [AT]GATA[AG]; |
502-551 |
2.72e-15 |
|
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
Pssm-ID: 214648 [Multi-domain] Cd Length: 52 Bit Score: 71.30 E-value: 2.72e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 672054330 502 KGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGEL-PPIEKPVDPP 551
Cdd:smart00401 2 SGRSCSNCGTTETPLWRRGPSGNKTLCNACGLYYKKHGGLkRPLSLKKDGI 52
|
|
| ZnF_GATA |
cd00202 |
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ... |
505-559 |
3.29e-15 |
|
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
Pssm-ID: 238123 [Multi-domain] Cd Length: 54 Bit Score: 71.25 E-value: 3.29e-15
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 672054330 505 ACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPvDPPPFMFKPVK 559
Cdd:cd00202 1 ACSNCGTTTTPLWRRGPSGGSTLCNACGLYWKKHGVMRPLSKR-KKDQIKRRNRK 54
|
|
| ELM2 |
pfam01448 |
ELM2 domain; The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown ... |
285-335 |
1.54e-12 |
|
ELM2 domain; The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex. The domain is usually found to the N terminus of a myb-like DNA binding domain pfam00249. ELM2 is also found associated with an ARID DNA binding domain pfam01388 in Swiss:O82364. This suggests that ELM2 may also be involved in DNA binding, or perhaps is a protein-protein interaction domain.
Pssm-ID: 460214 Cd Length: 53 Bit Score: 63.40 E-value: 1.54e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 672054330 285 IRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMP--GVSDCDLLMYLRAARS 335
Cdd:pfam01448 1 IRVGPRYQAEIPELLPPSEEEDRYEEEDELLVWDPnhNLPDRKLDEYLVVARS 53
|
|
| GATA |
pfam00320 |
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ... |
506-541 |
1.25e-11 |
|
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.
Pssm-ID: 425605 [Multi-domain] Cd Length: 36 Bit Score: 60.41 E-value: 1.25e-11
10 20 30
....*....|....*....|....*....|....*.
gi 672054330 506 CRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGEL 541
Cdd:pfam00320 1 CSNCGTTKTPLWRRGPNGNRTLCNACGLYYKKKGLK 36
|
|
| BAH |
pfam01426 |
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ... |
102-280 |
6.30e-10 |
|
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.
Pssm-ID: 460207 Cd Length: 120 Bit Score: 58.47 E-value: 6.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 102 VVYRPGDCVYIESRRPNTPYFICSIQDFKlvhnsqaccrspapalCDPPACSLPVasqppqhlseagrgpvgskrdhllm 181
Cdd:pfam01426 1 ETYSVGDFVLVEPDDADEPYYVARIEELF----------------EDTKNGKKMV------------------------- 39
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 182 NVKWYYRQSEVPdsvyqHLVQDRHNEndsgrelvitdpviknRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFK-A 260
Cdd:pfam01426 40 RVQWFYRPEETV-----HRAGKAFNK----------------DELFLSDEEDDVPLSAIIGKCSVLHKSDLESLDPYKiK 98
|
170 180
....*....|....*....|
gi 672054330 261 RVDSFFYILGYNPETRRLNS 280
Cdd:pfam01426 99 EPDDFFCELLYDPKTKSFKK 118
|
|
| BAH |
smart00439 |
Bromo adjacent homology domain; |
104-280 |
1.55e-09 |
|
Bromo adjacent homology domain;
Pssm-ID: 214664 [Multi-domain] Cd Length: 121 Bit Score: 57.30 E-value: 1.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 104 YRPGDCVYIESRRPNTPYFICSIQDfklvhnsqaccrspapaLCDPPACSLPVASQppqhlseagrgpvgskrdhllmnV 183
Cdd:smart00439 2 ISVGDFVLVEPDDADEPYYIGRIEE-----------------IFETKKNSESKMVR-----------------------V 41
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 184 KWYYRQSEVPdsvyqHLVQDRHNENdsgrelvitdpviknrELFISDYVDTYHAAALRGKCNISHFSDIF--AAREFKAR 261
Cdd:smart00439 42 RWFYRPEETV-----LEKAALFDKN----------------EVFLSDEYDTVPLSDIIGKCNVLYKSDYPglRPEGSIGE 100
|
170
....*....|....*....
gi 672054330 262 VDSFFYILGYNPETRRLNS 280
Cdd:smart00439 101 PDVFFCESAYDPEKGSFKK 119
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
731-897 |
1.52e-08 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 59.66 E-value: 1.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 731 QM-LQTQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPatsQPPNQTQSTVAPAAhtlIQQTPtlhppr 809
Cdd:pfam09770 202 AMrAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQP---QQPQQHPGQGHPVT---ILQRP------ 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 810 lpsphpplQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQtgpLLQHP---------------GPPQPFGLTPQSSQGQG 874
Cdd:pfam09770 270 --------QSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQ---ILQNPnrlsaarvgypqnpqPGVQPAPAHQAHRQQGS 338
|
170 180
....*....|....*....|...
gi 672054330 875 PLGPSPAAAHPHSTIQLPASQSA 897
Cdd:pfam09770 339 FGRQAPIITHPQQLAQLSEEEKA 361
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
544-728 |
3.48e-08 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 58.38 E-value: 3.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 544 IEKPVDPP----PFMFKPVKEEDDGL----SGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSA 615
Cdd:NF033609 539 IDKPVVPEqpdePGEIEPIPEDSDSDpgsdSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDS 618
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 616 ASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE-DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVN 693
Cdd:NF033609 619 ASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDS 698
|
170 180 190
....*....|....*....|....*....|....*
gi 672054330 694 DEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 728
Cdd:NF033609 699 DSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 732
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
539-1028 |
3.94e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.80 E-value: 3.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 539 GELPPIEKPVDPPPFMFKPVKEeddglsgkhSMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNE--DVRSSGRNSPSAA 616
Cdd:PHA03247 2549 GDPPPPLPPAAPPAAPDRSVPP---------PRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDrgDPRGPAPPSPLPP 2619
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 617 STSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTEDTDRATSKKTKTqeiSRPNSPSEGEGESSDSRSVNDEG 696
Cdd:PHA03247 2620 DTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA---AQASSPPQRPRRRAARPTVGSLT 2696
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 697 SS-----DPKDIDQDNRSTSPSIPSPqdnesdsdsSAQQQMLQTQPPALQAPSGAASAPSTAPPGTtqlPTPGPTPSATT 771
Cdd:PHA03247 2697 SLadpppPPPTPEPAPHALVSATPLP---------PGPAAARQASPALPAAPAPPAVPAGPATPGG---PARPARPPTTA 2764
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 772 VPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPslhgqgPPGPHSLQTG 851
Cdd:PHA03247 2765 GPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL------PPPTSAQPTA 2838
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 852 PllqhPGPPQPFGLTPQSSQGQGPLGPSPAAAHPHSTIQLPASQSalqpqqppreqplppaplampHIKPPPTTPIPQLP 931
Cdd:PHA03247 2839 P----PPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPA---------------------RPPVRRLARPAVSR 2893
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 932 APQAHKHPPHLSGPSPfsmnanlppppalkPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASH 1011
Cdd:PHA03247 2894 STESFALPPDQPERPP--------------QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
|
490
....*....|....*..
gi 672054330 1012 PTTGGLHQVPSQSPFPQ 1028
Cdd:PHA03247 2960 PQPWLGALVPGRVAVPR 2976
|
|
| BAH |
cd04370 |
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). ... |
104-276 |
8.70e-08 |
|
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in mammalian DNA methyltransferases and the MTA1 subunits of histone deacetylase complexes. A BAH domain is also found in Yeast Sir3p and in the origin receptor complex protein 1 (Orc1p), where it was found to interact with the N-terminal lobe of the silence information regulator 1 protein (Sir1p), confirming the initial hypothesis that BAH plays a role in protein-protein interactions.
Pssm-ID: 239835 [Multi-domain] Cd Length: 123 Bit Score: 52.39 E-value: 8.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 104 YRPGDCVYIE--SRRPNTPYFICSIQDFklvhnsqaccrspapalcdppacslpvasqppqhlseagrgpVGSKRDHLLM 181
Cdd:cd04370 4 YEVGDSVYVEpdDSIKSDPPYIARIEEL------------------------------------------WEDTNGSKQV 41
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 182 NVKWYYRQSEVPDSVYQHlvqdrHNEndsgrelvitdpviknRELFISDYVDTYHAAALRGKCNISHFSDIF--AAREFK 259
Cdd:cd04370 42 KVRWFYRPEETPKGLSPF-----ALR----------------RELFLSDHLDEIPVESIIGKCKVLFVSEFEglKQRPNK 100
|
170
....*....|....*..
gi 672054330 260 ARVDSFFYILGYNPETR 276
Cdd:cd04370 101 IDTDDFFCRLAYDPTTK 117
|
|
| BAH_fungalPHD |
cd04710 |
BAH, or Bromo Adjacent Homology domain, as present in fungal proteins containing PHD domains. ... |
100-277 |
1.66e-07 |
|
BAH, or Bromo Adjacent Homology domain, as present in fungal proteins containing PHD domains. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
Pssm-ID: 240061 Cd Length: 135 Bit Score: 51.99 E-value: 1.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 100 DDVVYRPGDCVYIESRRPNTPYFICSIQDFklvhnsqaccrspapalcdppacsLPVASQPPQHLSEAGRGPVGSKRdhl 179
Cdd:cd04710 8 NGELLKVNDHIYMSSEPPGEPYYIGRIMEF------------------------VPKHEFPSGIHARVFPASYFQVR--- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 180 lMNvkWYYRQSEVpdsvyqhlvqDRHNENDSgrelvitdpviknRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFK 259
Cdd:cd04710 61 -LN--WYYRPRDI----------SRRVVADS-------------RLLYASMHSDICPIGSVRGKCTVRHRDQIPDLEEYK 114
|
170
....*....|....*...
gi 672054330 260 ARVDSFFYILGYNPETRR 277
Cdd:cd04710 115 KRPNHFYFDQLFDRYILR 132
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
700-946 |
4.23e-07 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 55.04 E-value: 4.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 700 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQT------QP---PALQAPSGAASAPSTAPPGTTQLPTPGPTPSAT 770
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTgyekykEPepiPDLQVDASLWGVAPKKAAAPAPAPQPAAQPASL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 771 TVPP---------------QGSPATSQPPNQTQSTvaPAAHTLIQQTPtlhpprlpspHPPLQPMTAPPSQNSAQPHPQP 835
Cdd:pfam09770 187 PAPSrkmmsleeveaamraQAKKPAQQPAPAPAQP--PAAPPAQQAQQ----------QQQFPPQIQQQQQPQQQPQQPQ 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 836 SLHGQGPPgPHSLQtGPLLQHPGPPQPFGLTPQSSQGQGPlgpSPAAAHPHSTIQLPASQSAlqpqQPPREQPLPPAPLA 915
Cdd:pfam09770 255 QHPGQGHP-VTILQ-RPQSPQPDPAQPSIQPQAQQFHQQP---PPVPVQPTQILQNPNRLSA----ARVGYPQNPQPGVQ 325
|
250 260 270
....*....|....*....|....*....|.
gi 672054330 916 MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 946
Cdd:pfam09770 326 PAPAHQAHRQQGSFGRQAPIITHPQQLAQLS 356
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
707-1041 |
9.00e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.17 E-value: 9.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 707 NRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSG------AASAPSTAPPGTTQLPTPGPTPS-ATTVPPQGSPA 779
Cdd:PHA03247 2565 DRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDdrgdprGPAPPSPLPPDTHAPDPPPPSPSpAANEPDPHPPP 2644
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 780 TSQPPNQTQSTVAPAAHTLIQQT-----PTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSlhgQGPPGPHSLQTGPLL 854
Cdd:PHA03247 2645 TVPPPERPRDDPAPGRVSRPRRArrlgrAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPP---TPEPAPHALVSATPL 2721
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 855 QhPGPPQPFGLTPQSSQGQGPLGPSPAAAHPHSTIQL---PASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLP 931
Cdd:PHA03247 2722 P-PGPAAARQASPALPAAPAPPAVPAGPATPGGPARParpPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS 2800
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 932 APQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASH 1011
Cdd:PHA03247 2801 PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPAR 2880
|
330 340 350
....*....|....*....|....*....|....*.
gi 672054330 1012 PTTGGLHQ---VPSQSPFPQHPFVPGGP---PPITP 1041
Cdd:PHA03247 2881 PPVRRLARpavSRSTESFALPPDQPERPpqpQAPPP 2916
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
715-885 |
2.59e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.21 E-value: 2.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 715 PSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGttqlPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPA 794
Cdd:PRK07764 601 PAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAA----PAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGA 676
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 795 AHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSLH------GQGPPGPHSLQTGPLLQHPG-PPQPFGLTP 867
Cdd:PRK07764 677 APAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQppqaaqGASAPSPAADDPVPLPPEPDdPPDPAGAPA 756
|
170
....*....|....*...
gi 672054330 868 QSSQGQGPLGPSPAAAHP 885
Cdd:PRK07764 757 QPPPPPAPAPAAAPAAAP 774
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-728 |
2.80e-05 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 49.14 E-value: 2.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE 658
Cdd:NF033609 618 SASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 697
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672054330 659 -DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 728
Cdd:NF033609 698 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 768
|
|
| PRK13042 |
PRK13042 |
superantigen-like protein SSL4; Reviewed; |
709-786 |
3.62e-05 |
|
superantigen-like protein SSL4; Reviewed;
Pssm-ID: 183854 [Multi-domain] Cd Length: 291 Bit Score: 47.32 E-value: 3.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 709 STSPSIPSPQDNESDSDSSAQQQMLQTQPPALQaPSGAASAPSTAPPGTTQLPTPGPTPSATTVP------PQgSPATSQ 782
Cdd:PRK13042 17 TTGVITTTTQAANATTPSSTKVEAPQSTPPSTK-VEAPQSKPNATTPPSTKVEAPQQTPNATTPSstkvetPQ-SPTTKQ 94
|
....
gi 672054330 783 PPNQ 786
Cdd:PRK13042 95 VPTE 98
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
541-1056 |
3.67e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.78 E-value: 3.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 541 LPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLR---SGRKKQPASPDGRASPVNEDVRSSGRnSPSAAS 617
Cdd:PHA03247 2617 LPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRvsrPRRARRLGRAAQASSPPQRPRRRAAR-PTVGSL 2695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 618 TSSNDSKAEAVKKSAKKVKEEAASPL---KNTKRQREKVASDTEDTDRATSKKTKTQEISRPNSPSEGEGESSDSRSVND 694
Cdd:PHA03247 2696 TSLADPPPPPPTPEPAPHALVSATPLppgPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 695 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTA---PPGTTQLPTPGPTPSATT 771
Cdd:PHA03247 2776 AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAqptAPPPPPGPPPPSLPLGGS 2855
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 772 VPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHslqtg 851
Cdd:PHA03247 2856 VAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ----- 2930
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 852 PLLQHPGPPQPfGLTPQSsQGQGPLGPSPAAAHPHSTIQLPASQSAlqpqqppreqplppaplamphIKPPPTTPIPQLP 931
Cdd:PHA03247 2931 PPPPPPPRPQP-PLAPTT-DPAGAGEPSGAVPQPWLGALVPGRVAV---------------------PRFRVPQPAPSRE 2987
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 932 APQAHKHPPHLSGPSPFSMNAnlppppalkplSSLSthhppsahppplqLMPQSQPLPSSPAQ---PPGLTQSQSLPPPA 1008
Cdd:PHA03247 2988 APASSTPPLTGHSLSRVSSWA-----------SSLA-------------LHEETDPPPVSLKQtlwPPDDTEDSDADSLF 3043
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 672054330 1009 ASHPTTGGLHQVPSQSPFPQHPFvpggppPITPPSCPPTSTPPAGPSS 1056
Cdd:PHA03247 3044 DSDSERSDLEALDPLPPEPHDPF------AHEPDPATPEAGARESPSS 3085
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
395-440 |
3.89e-05 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 42.60 E-value: 3.89e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 672054330 395 WTEDEVKRFVKGLRQYG-KNFFRIRKElLPNKETGELITFYYYWKKT 440
Cdd:smart00717 4 WTEEEDELLIELVKKYGkNNWEKIAKE-LPGRTAEQCRERWRNLLKP 49
|
|
| SANT |
cd00167 |
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
395-438 |
3.95e-05 |
|
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.
Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 42.18 E-value: 3.95e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 672054330 395 WTEDEVKRFVKGLRQYG-KNFFRIRKElLPNKETGELITFYYYWK 438
Cdd:cd00167 2 WTEEEDELLLEAVKKYGkNNWEKIAKE-LPGRTPKQCRERWRNLL 45
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
685-791 |
4.52e-05 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 47.33 E-value: 4.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 685 ESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTPG 764
Cdd:PRK10856 149 QSSAELSQNSGQSVPLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAP 228
|
90 100
....*....|....*....|....*..
gi 672054330 765 PTPSATTVPPQGSPATSQPPNQTQSTV 791
Cdd:PRK10856 229 ATPDGAAPLPTDQAGVSTPAADPNALV 255
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
646-852 |
4.57e-05 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 48.37 E-value: 4.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 646 TKRQREKVASDTEDTDRATSKKTKTQEISRPNSPSEGEGESSDSRSVN--DEGSSDPKDIDQDNRSTSPSiPSPQDNESD 723
Cdd:pfam05109 422 SKAPESTTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVStaDVTSPTPAGTTSGASPVTPS-PSPRDNGTE 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 724 SdssaqqqmlqtQPPALQAPSGAASAPS---TAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQ 800
Cdd:pfam05109 501 S-----------KAPDMTSPTSAVTTPTpnaTSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNA 569
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 672054330 801 QTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQTGP 852
Cdd:pfam05109 570 TIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSP 621
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
690-802 |
4.89e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 47.85 E-value: 4.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 690 RSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESdSDSSAQQQMLQTQPPALQAPSgAASAPSTAPPGTTQLPTPGPTPSA 769
Cdd:PRK14971 363 TQKGDDASGGRGPKQHIKPVFTQPAAAPQPSAA-AAASPSPSQSSAAAQPSAPQS-ATQPAGTPPTVSVDPPAAVPVNPP 440
|
90 100 110
....*....|....*....|....*....|....*..
gi 672054330 770 TTVPPQGSPATSQPPNQ----TQSTVAPAAHTLIQQT 802
Cdd:PRK14971 441 STAPQAVRPAQFKEEKKipvsKVSSLGPSTLRPIQEK 477
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
724-880 |
5.55e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.06 E-value: 5.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 724 SDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTP 803
Cdd:PRK07764 599 GPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAP 678
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672054330 804 TlhpprlpSPHPPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSlqtGPLLQHPGPPQPFGLTPQSSQGQGPLGPSP 880
Cdd:PRK07764 679 A-------APPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQAD---DPAAQPPQAAQGASAPSPAADDPVPLPPEP 745
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
736-885 |
8.48e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 8.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 736 QPPALQAPSGAASAPSTAPPGTTQL-------PTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPP 808
Cdd:PRK07764 583 QVEAVVGPAPGAAGGEGPPAPASSGppeeaarPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDA 662
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672054330 809 RLPSPHPPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQTGPLLQHPGP-PQPFGLTPQSSQGQGPLGPSPAAAHP 885
Cdd:PRK07764 663 SDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQaDDPAAQPPQAAQGASAPSPAADDPVP 740
|
|
| Myb_DNA-binding |
pfam00249 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
395-438 |
1.04e-04 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 40.95 E-value: 1.04e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 672054330 395 WTEDEVKRFVKGLRQYGKNFFRIrKELLPNKETGELITFYYYWK 438
Cdd:pfam00249 4 WTPEEDELLLEAVEKLGNRWKKI-AKLLPGRTDNQCKNRWQNYL 46
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
722-862 |
1.51e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.52 E-value: 1.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 722 SDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPAtsqPPNQTQSTVAPAAHtliQQ 801
Cdd:PRK07764 367 ASDDERGLLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPA---PAAAPQPAPAPAPA---PA 440
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672054330 802 TPTLHPPRLPSPHPPLQPMTAPPSQnsAQPHPQPSLHGQGPPGPHSLQTGPLLQHPGPPQP 862
Cdd:PRK07764 441 PPSPAGNAPAGGAPSPPPAAAPSAQ--PAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAA 499
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
738-868 |
1.89e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 46.25 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 738 PALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAhtliqqTPTLHPPRLPSPHPPL 817
Cdd:PRK14951 383 RPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAA------APAAVALAPAPPAQAA 456
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 672054330 818 QPMTAPPSQNSAQPHPQPslhgqgPPGPHSLQTGPLLQHPGPPQPF--GLTPQ 868
Cdd:PRK14951 457 PETVAIPVRVAPEPAVAS------AAPAPAAAPAAARLTPTEEGDVwhATVQQ 503
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
690-795 |
2.31e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 46.04 E-value: 2.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 690 RSVNDEGSSDPK--DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQlPTPGPTP 767
Cdd:PRK12270 17 QYLADPNSVDPSwrEFFADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAA-AAAAAAA 95
|
90 100 110
....*....|....*....|....*....|.
gi 672054330 768 SATTVPPQGSPATSQPPNQTQSTV---APAA 795
Cdd:PRK12270 96 PAAPPAAAAAAAPAAAAVEDEVTPlrgAAAA 126
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
660-845 |
2.37e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 2.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 660 TDRATSKKTKTQEISRPnSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPA 739
Cdd:PRK07764 599 GPPAPASSGPPEEAARP-AAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 740 LQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPPRLPSPHPPLQP 819
Cdd:PRK07764 678 PAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQ 757
|
170 180
....*....|....*....|....*.
gi 672054330 820 MTAPPSQNSAQPHPQPSLHGQGPPGP 845
Cdd:PRK07764 758 PPPPPAPAPAAAPAAAPPPSPPSEEE 783
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
717-831 |
2.76e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 45.54 E-value: 2.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 717 PQDNESDSDSSAQQQMLQ---TQPPALQAPSgAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQstvAP 793
Cdd:PRK14971 363 TQKGDDASGGRGPKQHIKpvfTQPAAAPQPS-AAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVP---VN 438
|
90 100 110
....*....|....*....|....*....|....*...
gi 672054330 794 AAHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQP 831
Cdd:PRK14971 439 PPSTAPQAVRPAQFKEEKKIPVSKVSSLGPSTLRPIQE 476
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-778 |
4.61e-04 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.90 E-value: 4.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE 658
Cdd:NF033609 684 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 659 -DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSpsipspqDNESDSDSSAQQQMLQTQ 736
Cdd:NF033609 764 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDS-------DSDSDSDSDSDSDSDSDS 836
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 672054330 737 PPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSP 778
Cdd:NF033609 837 DSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPPNSP 878
|
|
| rad23 |
TIGR00601 |
UV excision repair protein Rad23; All proteins in this family for which functions are known ... |
643-792 |
6.30e-04 |
|
UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273167 [Multi-domain] Cd Length: 378 Bit Score: 44.12 E-value: 6.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 643 LKNTKRQREKVASDTEDTDRATSKKTKtQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDN---------RSTSPS 713
Cdd:TIGR00601 5 FKTLQQQKFKIDMEPDETVKELKEKIE-AEQGKDAYPVAQQKLIYSGKILSDDKTVKEYKIKEKDfvvvmvskpKTGTGK 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672054330 714 IPSPqdnESDSDSSAQqqmlqtqpPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVA 792
Cdd:TIGR00601 84 VAPP---AATPTSAPT--------PTPSPPASPASGMSAAPASAVEEKSPSEESATATAPESPSTSVPSSGSDAASTLV 151
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-784 |
6.31e-04 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.51 E-value: 6.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTe 658
Cdd:NF033609 690 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS- 768
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 659 DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPS-IPSPQDNESDSDSSAQQQMLQTQ 736
Cdd:NF033609 769 DSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDS 848
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 672054330 737 PPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPP 784
Cdd:NF033609 849 DSDSDSDSESDSNSDSESGSNNNVVPPNSPKNGTNASNKNEAKDSKEP 896
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
737-908 |
7.62e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.21 E-value: 7.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 737 PPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPPRLPSPHPP 816
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 817 LQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQTGPLLQHPGP-PQPFGLTPQSSQGQGPLGPSPAAAHPhstiqLPASQ 895
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQaDDPAAQPPQAAQGASAPSPAADDPVP-----LPPEP 745
|
170
....*....|...
gi 672054330 896 SALQPQQPPREQP 908
Cdd:PRK07764 746 DDPPDPAGAPAQP 758
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-728 |
8.85e-04 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 44.13 E-value: 8.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE 658
Cdd:NF033609 630 SASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 709
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672054330 659 -----DTDRATSKKTKTQEISRPNSPSEGEGES---SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 728
Cdd:NF033609 710 sdsdsDSDSDSDSDSDSDSDSDSDSDSDSDSDSdsdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 786
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
579-728 |
1.11e-03 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 43.74 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 579 SMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTE 658
Cdd:NF033609 648 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 727
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672054330 659 -----DTDRATSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 728
Cdd:NF033609 728 sdsdsDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 802
|
|
| TALPID3 |
pfam15324 |
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ... |
742-892 |
1.11e-03 |
|
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.
Pssm-ID: 434634 [Multi-domain] Cd Length: 1288 Bit Score: 43.72 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 742 APSGAASAPSTAPPGTTQLPTPGPTPSATtvPPQGSPatsqPPNQTQSTVapaahtliqQTPTLhppRLPSPHPPLQPMT 821
Cdd:pfam15324 966 EPPVAASVPGDLPTKETLLPTPVPTPQPT--PPCSPP----SPLKEPSPV---------KTPDS---SPCVSEHDFFPVK 1027
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672054330 822 APPSQNSAQPHPQPSLhgQGPPGPHSLQTGPLLQHPGPPqpfglTPQSSQGQGPLgPSPAAAHPHSTIQLP 892
Cdd:pfam15324 1028 EIPPEKGADTGPAVSL--VITPTVTPIATPPPAATPTPP-----LSENSIDKLKS-PSPELPKPWEDSDLP 1090
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
644-846 |
1.29e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 43.52 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 644 KNTKRQRekvaSDTEDTDRATSKKTKTQEI----SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP-SPQ 718
Cdd:PTZ00449 595 KKPKRPR----SAQRPTRPKSPKLPELLDIpkspKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPfDPK 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 719 DNES--DSDSSAQQQMLQTQPPALQAPSGAASAPSTAP-----PGTTQLPTPG--PTPSATTVPPQGSPATSQPPNQTQS 789
Cdd:PTZ00449 671 FKEKfyDDYLDAAAKSKETKTTVVLDESFESILKETLPetpgtPFTTPRPLPPklPRDEEFPFEPIGDPDAEQPDDIEFF 750
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672054330 790 TVAPAAHTLIQQTPTLHPPRLPSPHPPLQP----MTAPPSQNSAQPHpQPSLHGQGPPGPH 846
Cdd:PTZ00449 751 TPPEEERTFFHETPADTPLPDILAEEFKEEdihaETGEPDEAMKRPD-SPSEHEDKPPGDH 810
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
706-1024 |
1.30e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.62 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 706 DNRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGttqlPTPGPTPSATTVPPQGSPATSQPPN 785
Cdd:PHA03307 16 EGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFE----PPTGPPPGPGTEAPANESRSTPTWS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 786 QTQSTVAPAAHTLIQQTPTlhPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSlqtgpllqhpGPPQPFGL 865
Cdd:PHA03307 92 LSTLAPASPAREGSPTPPG--PSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAAS----------PPAAGASP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 866 TPQSSQGQGPLGPSPAAAHPHSTIQLPASQSAlqpqqppreqplppaplamphikpppttPIPQLPAPQAHKHPPHL--- 942
Cdd:PHA03307 160 AAVASDAASSRQAALPLSSPEETARAPSSPPA----------------------------EPPPSTPPAAASPRPPRrss 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 943 --------SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTT 1014
Cdd:PHA03307 212 pisasassPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSP 291
|
330
....*....|
gi 672054330 1015 GGLHQVPSQS 1024
Cdd:PHA03307 292 RERSPSPSPS 301
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
727-1012 |
1.51e-03 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.10 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 727 SAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTP-----------GPTP------SATTVPPQGSPATSQPPnqtqs 789
Cdd:pfam09770 103 NRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPvrtgyekykepEPIPdlqvdaSLWGVAPKKAAAPAPAP----- 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 790 TVAPAAHTLIQQTPTLHPPrlpsphpplQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQTGPLLQHPGPPQPFGLTPQS 869
Cdd:pfam09770 178 QPAAQPASLPAPSRKMMSL---------EEVEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQ 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 870 SQGQGPlgPSPAAAHPHSTIQLPASQSAlqpqqppreqplppaplamphikPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 949
Cdd:pfam09770 249 QPQQPQ--QHPGQGHPVTILQRPQSPQP-----------------------DPAQPSIQPQAQQFHQQPPPVPVQPTQIL 303
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672054330 950 MNANLPPPPALKPLSslsthhppsahppplQLMPQSQPLPSSPAQPPGltQSQSLPPPAASHP 1012
Cdd:pfam09770 304 QNPNRLSAARVGYPQ---------------NPQPGVQPAPAHQAHRQQ--GSFGRQAPIITHP 349
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
737-824 |
1.68e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 42.87 E-value: 1.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 737 PPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATsqPPNQTQSTVAPAAHTLIQQTPTLHPPRLPSPHPP 816
Cdd:PRK14950 365 APQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETAT--PPPVPPRPVAPPVPHTPESAPKLTRAAIPVDEKP 442
|
....*...
gi 672054330 817 LQPMTAPP 824
Cdd:PRK14950 443 KYTPPAPP 450
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
759-878 |
1.84e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 42.84 E-value: 1.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 759 QLPTPGPTPSATTVPPQG-SPATSQPPNQTQSTVAPAAHTliQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSL 837
Cdd:PRK14971 361 QLTQKGDDASGGRGPKQHiKPVFTQPAAAPQPSAAAAASP--SPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVN 438
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 672054330 838 hgqgPPGPHSLQTGPllQHPGPPQPFGLTPQSSQGQGPLGP 878
Cdd:PRK14971 439 ----PPSTAPQAVRP--AQFKEEKKIPVSKVSSLGPSTLRP 473
|
|
| PRK10927 |
PRK10927 |
cell division protein FtsN; |
676-862 |
2.21e-03 |
|
cell division protein FtsN;
Pssm-ID: 236797 [Multi-domain] Cd Length: 319 Bit Score: 41.97 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 676 PNSPSEGeGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSsaQQQMLQTQPpalQAPSGAASAPSTAPP 755
Cdd:PRK10927 99 PTEPSAG-GEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQ--RQQTLQRQR---QAQQLAEQQRLAQQS 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 756 GTTQLPTPGPTPSATTVPPQGSPatsQPPNQTQStvapaahtliqQTPtlhpprlpsphppLQPMTAPPSQNSAQPHPQp 835
Cdd:PRK10927 173 RTTEQSWQQQTRTSQAAPVQAQP---RQSKPAST-----------QQP-------------YQDLLQTPAHTTAQSKPQ- 224
|
170 180
....*....|....*....|....*..
gi 672054330 836 slhgqgppgphslQTGPLLQHPGPPQP 862
Cdd:PRK10927 225 -------------QAAPVTRAADAPKP 238
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
718-805 |
2.49e-03 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 41.94 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 718 QDNESDSDSSAQQQMLQT--QPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQgSPATSQPPNQTQSTVAPAA 795
Cdd:PRK10856 149 QSSAELSQNSGQSVPLDTstTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNA-VVAPSQANVDTAATPAPAA 227
|
90
....*....|
gi 672054330 796 HTLIQQTPTL 805
Cdd:PRK10856 228 PATPDGAAPL 237
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
716-797 |
2.60e-03 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 41.94 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 716 SPQDNES---DSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVA 792
Cdd:PRK10856 155 SQNSGQSvplDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGA 234
|
....*
gi 672054330 793 PAAHT 797
Cdd:PRK10856 235 APLPT 239
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
726-836 |
2.76e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.28 E-value: 2.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 726 SSAQQQMLQTQPPALQAPSGAASAPSTAP---PGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAahtliQQT 802
Cdd:PRK07764 393 APAAAAPSAAAAAPAAAPAPAAAAPAAAAapaPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSA-----QPA 467
|
90 100 110
....*....|....*....|....*....|....
gi 672054330 803 PTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPS 836
Cdd:PRK07764 468 PAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPA 501
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
757-885 |
2.95e-03 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 42.02 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 757 TTQLPTPGPTPSATTvppqgsPATSQPPNQtqstvAPAAHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPS 836
Cdd:PHA03269 19 IANLNTNIPIPELHT------SAATQKPDP-----APAPHQAASRAPDPAVAPTSAASRKPDLAQAPTPAASEKFDPAPA 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 672054330 837 LHGQG--PPGPHSLQTGPLLQHPGPPQPFGLTPQSSQGQGPLGPSPAAAHP 885
Cdd:PHA03269 88 PHQAAsrAPDPAVAPQLAAAPKPDAAEAFTSAAQAHEAPADAGTSAASKKP 138
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
734-950 |
4.03e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.79 E-value: 4.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 734 QTQPPALQAPSGAASAPSTAPPgTTQLPTPGPTPSATTVPPQgSPATSQPPNQTQSTVAPAAHTLiqqtptlhPPRLPSP 813
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAP-AAAAPAPAAPPAAPAAAPA-AAAAARAVAAAPARRSPAPEAL--------AAARQAS 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 814 HPPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQTGPllqhPGPPQPFGLTPQSSQGQGP---LGPSPAAAHPHSTIQ 890
Cdd:PRK12323 441 ARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAA----PARAAPAAAPAPADDDPPPweeLPPEFASPAPAQPDA 516
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 891 LPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSM 950
Cdd:PRK12323 517 APAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDM 576
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
760-885 |
4.43e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.99 E-value: 4.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 760 LPTPGPTPSATtvpPQGSPATSQPPNQTQSTVAPAAHtliQQTPtlhpprlpsphppLQPMTAPPSQNSAQPHPQPSLHG 839
Cdd:PRK10263 744 LFTPIVEPVQQ---PQQPVAPQQQYQQPQQPVAPQPQ---YQQP-------------QQPVAPQPQYQQPQQPVAPQPQY 804
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 672054330 840 QGPPGPhslqTGPLLQHPGPPQPFGLTPQSSQGQGPLGPSPAAA--HP 885
Cdd:PRK10263 805 QQPQQP----VAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTllHP 848
|
|
| PRK10905 |
PRK10905 |
cell division protein DamX; Validated |
678-894 |
4.65e-03 |
|
cell division protein DamX; Validated
Pssm-ID: 236792 [Multi-domain] Cd Length: 328 Bit Score: 41.08 E-value: 4.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 678 SPSEGEGESSDSRSVNDEGSSDpkdiDQDNRSTspsiPSP-QDNESDSDSSAQQQMlqTQPPALQAPSGAASAPstAPPG 756
Cdd:PRK10905 24 STSSSDQTASGEKSIDLAGNAT----DQANGVQ----PAPgTTSAEQTAGNTQQDV--SLPPISSTPTQGQTPV--ATDG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 757 TTQLPTPG------------------------PTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPPRLPS 812
Cdd:PRK10905 92 QQRVEVQGdlnnaltqpqnqqqlnnvavnstlPTEPATVAPVRNGNASRQTAKTQTAERPATTRPARKQAVIEPKKPQAT 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 813 PHPPLQPMTAPP--SQNSAQPHPQPSLHGQGPPGPHSLQTGPLLQHPGPPQPFGLTPQSSQGQGPLGPSPAAAHPHSTIQ 890
Cdd:PRK10905 172 AKTEPKPVAQTPkrTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGGKTAGNVGSLKSAPSSHYTLQ 251
|
....
gi 672054330 891 LPAS 894
Cdd:PRK10905 252 LSSS 255
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
685-794 |
4.82e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.61 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 685 ESSDSRSVNDEGSSDP---KDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLP 761
Cdd:PRK10263 728 EFSPMKALLDDGPHEPlftPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQP 807
|
90 100 110
....*....|....*....|....*....|...
gi 672054330 762 TPGPTPSATTVPPQGSPATSQPPNQTQSTVAPA 794
Cdd:PRK10263 808 QQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQ 840
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
710-879 |
4.94e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.40 E-value: 4.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 710 TSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQL-PTPGPTPSATTVPPQGSP---ATSQPPN 785
Cdd:PRK12323 400 AAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPaPAPAAAPAAAARPAAAGPrpvAAAAAAA 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 786 QTQSTVAPAAHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSlhGQGPPGPHSLQTGPLLQHPGPPQPFGL 865
Cdd:PRK12323 480 PARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPA--TADPDDAFETLAPAPAAAPAPRAAAAT 557
|
170
....*....|....
gi 672054330 866 TPQSSQGQGPLGPS 879
Cdd:PRK12323 558 EPVVAPRPPRASAS 571
|
|
| PRK10856 |
PRK10856 |
cytoskeleton protein RodZ; |
728-844 |
5.05e-03 |
|
cytoskeleton protein RodZ;
Pssm-ID: 236776 [Multi-domain] Cd Length: 331 Bit Score: 40.78 E-value: 5.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 728 AQQQMLQT---QPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNqtqstvAPAAHTliqqtpt 804
Cdd:PRK10856 138 AQQEEITTmadQSSAELSQNSGQSVPLDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAP------APAVDP------- 204
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 672054330 805 lhpprlpsphppLQPMTAPPSQNSAQPHPQPSLHGQGPPG 844
Cdd:PRK10856 205 ------------QQNAVVAPSQANVDTAATPAPAAPATPD 232
|
|
| PRK12495 |
PRK12495 |
hypothetical protein; Provisional |
671-800 |
5.49e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 183558 [Multi-domain] Cd Length: 226 Bit Score: 40.24 E-value: 5.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 671 QEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQmlQTQPPALQApsgAASAP 750
Cdd:PRK12495 66 QPVTEDGAAGDDAGDGAEATAPSDAGSQASPDDDAQPAAEAEAADQSAPPEASSTSATDEA--ATDPPATAA---ARDGP 140
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 672054330 751 STAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQ 800
Cdd:PRK12495 141 TPDPTAQPATPDERRSPRQRPPVSGEPPTPSTPDAHVAGTLQAARESLVE 190
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
738-898 |
6.03e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 41.00 E-value: 6.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 738 PALQAPSGAASAPSTAPPGTTQ-LPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHpprlpsphpp 816
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQaTAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQ---------- 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 817 lqpmtaPPSQNSAQPHPQPSLHGQGPPGPHSLQtgPLLQHPGPPQPFGLTPQSSQGQGPLGPSPAAAHPHSTIQLPASQS 896
Cdd:PRK07994 431 ------RAQGATKAKKSEPAAASRARPVNSALE--RLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKK 502
|
..
gi 672054330 897 AL 898
Cdd:PRK07994 503 AL 504
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
641-800 |
6.30e-03 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 40.44 E-value: 6.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 641 SPLKNTKRQREKVASDTEDTDRATSKKTKTQEISRPNSPSEGEGESSDSrsvNDEGSSDPKDIDQDNRSTSPSIPSPQDN 720
Cdd:PRK11901 60 SPTEHESQQSSNNAGAEKNIDLSGSSSLSSGNQSSPSAANNTSDGHDAS---GVKNTAPPQDISAPPISPTPTQAAPPQT 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 721 ESD----------SDSSAQQQ------------MLQTQP--PALQAPSGAA-------SAPSTAPPGTTQLPTPGPTPSA 769
Cdd:PRK11901 137 PNGqqrielpgniSDALSQQQgqvnaasqnaqgNTSTLPtaPATVAPSKGAkvpataeTHPTPPQKPATKKPAVNHHKTA 216
|
170 180 190
....*....|....*....|....*....|...
gi 672054330 770 TTVPPQGSPATSQPPNQTQSTV--APAAHTLIQ 800
Cdd:PRK11901 217 TVAVPPATSGKPKSGAASARALssAPASHYTLQ 249
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
708-862 |
6.76e-03 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 40.80 E-value: 6.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 708 RSTSPSIPSPQDNESDSDSSAQQ-----QMLQTQPPALQAPSGAasaPSTAPPGTTqlptPGPTPSATTVPPQGSPATSQ 782
Cdd:pfam05539 183 EVSHPTYPSQVTPQSQPATQGHQtatanQRLSSTEPVGTQGTTT---SSNPEPQTE----PPPSQRGPSGSPQHPPSTTS 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 783 PPNQTQSTvaPAAHTLIQQTPTLHPPRLPSPHPPLQPMTaPPSQNSAQPHPQPSLHGQ--------GPPGPHSLQTGPLL 854
Cdd:pfam05539 256 QDQSTTGD--GQEHTQRRKTPPATSNRRSPHSTATPPPT-TKRQETGRPTPRPTATTQsgsspphsSPPGVQANPTTQNL 332
|
170
....*....|.
gi 672054330 855 ---QHPGPPQP 862
Cdd:pfam05539 333 vdcKELDPPKP 343
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
736-1084 |
7.31e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.08 E-value: 7.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 736 QPPALQAPSGAASAPStappgttqlPTPGPTPSATTVPPQGSPATSQPPNQTQ-STVAPAAHTLIQQTPTLHPPRLPSPH 814
Cdd:PHA03247 2482 RPAEARFPFAAGAAPD---------PGGGGPPDPDAPPAPSRLAPAILPDEPVgEPVHPRMLTWIRGLEELASDDAGDPP 2552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 815 PPLQPMTAPPSQNSAQPHPQPSLHGQGP--------PGPHSLQTGPLLQHPGPPQPFGLTPQSSQGQGPLGPSPAAAHPH 886
Cdd:PHA03247 2553 PPLPPAAPPAAPDRSVPPPRPAPRPSEPavtsrarrPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPS 2632
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 887 STIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP----------HLSGPSPFSMNANLPP 956
Cdd:PHA03247 2633 PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRaarptvgsltSLADPPPPPPTPEPAP 2712
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 957 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSlpPPAASHPTTGGLHQVPSQSPFPQHPfvpGGP 1036
Cdd:PHA03247 2713 HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPAR--PPTTAGPPAPAPPAAPAAGPPRRLT---RPA 2787
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 672054330 1037 PPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGNVPGAPSCPLPAVQ 1084
Cdd:PHA03247 2788 VASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQ 2835
|
|
| COG5644 |
COG5644 |
U3 small nucleolar RNA-associated protein 14 [Function unknown]; |
642-747 |
7.48e-03 |
|
U3 small nucleolar RNA-associated protein 14 [Function unknown];
Pssm-ID: 227931 [Multi-domain] Cd Length: 869 Bit Score: 40.84 E-value: 7.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 642 PLKNTKRQREKVASDTEDTDRATSKKTKTQeiSRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSP--SIPSPQD 719
Cdd:COG5644 126 DLDTLLDNDQPEKNESGNNDHATDKENLLE--SDASSSNDSESEESDSESEIESSDSDHDDENSDSKLDNLrnYIVSLKK 203
|
90 100 110
....*....|....*....|....*....|....
gi 672054330 720 NESDS------DSSAQQQMLQTQPPALQAPSGAA 747
Cdd:COG5644 204 DEADAesvlssDDNDSIEEIKYDPHETNKESGSS 237
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
735-1093 |
8.38e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 40.74 E-value: 8.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 735 TQPPALQAPSGAASAPSTAPPGttqlPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTlhpPRLPSPH 814
Cdd:PRK07764 391 AGAPAAAAPSAAAAAPAAAPAP----AAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSP---PPAAAPS 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 815 PPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQTGPLLQHPGP--------PQPFGLTPQSS--------------QG 872
Cdd:PRK07764 464 AQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDaatlrerwPEILAAVPKRSrktwaillpeatvlGV 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 873 QGP---LG-PSPAAAH-----PHSTIQLPASQSAL-----------QPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 932
Cdd:PRK07764 544 RGDtlvLGfSTGGLARrfaspGNAEVLVTALAEELggdwqveavvgPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAA 623
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 933 PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHP 1012
Cdd:PRK07764 624 PAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAP 703
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672054330 1013 T-TGGLHQVPSQSPFPQHPFVPGGPPPITPPSCP-----PTSTPPAGPSSSSQPPCSAAVSSGGNVPGAPSCPLPAVQiK 1086
Cdd:PRK07764 704 ApAATPPAGQADDPAAQPPQAAQGASAPSPAADDpvplpPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE-E 782
|
....*..
gi 672054330 1087 EEALDEA 1093
Cdd:PRK07764 783 EEMAEDD 789
|
|
| |
