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Conserved domains on  [gi|755534832|ref|XP_011241812|]
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carbohydrate sulfotransferase 3 isoform X1 [Mus musculus]

Protein Classification

sulfotransferase family protein( domain architecture ID 229543)

sulfotransferase family protein may utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to its substrate(s)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sulfotransfer_1 super family cl21551
Sulfotransferase domain;
267-451 3.67e-27

Sulfotransferase domain;


The actual alignment was detected with superfamily member pfam00685:

Pssm-ID: 473908 [Multi-domain]  Cd Length: 253  Bit Score: 109.35  E-value: 3.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534832  267 KDHVALKAVRIRQLEFLQPLV----------EDPRLDLRVIQLVRDPRAVLASRIVAFAGKYENwkKWLSEGQDQlsEDE 336
Cdd:pfam00685  56 YFDVAEGPVRLNALPSPRIIKthlplhllpkSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLL--KAPGTPFEF--VED 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534832  337 VQRLRGNCESIRLSAELGLRQpaWLRGRYMLVRYEDVARRPLQKAREMYSFAGIPLTPQ-----VEDWIQKNTQATRDSS 411
Cdd:pfam00685 132 FLNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEeldkiVKHLSFENMKGNPCLN 209

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 755534832  412 DVYSTQKNSS----EQFEKWRFSMPFKLAQVVQAACGPTMHLFG 451
Cdd:pfam00685 210 YSKLPKEVSPffrkGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
267-451 3.67e-27

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 109.35  E-value: 3.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534832  267 KDHVALKAVRIRQLEFLQPLV----------EDPRLDLRVIQLVRDPRAVLASRIVAFAGKYENwkKWLSEGQDQlsEDE 336
Cdd:pfam00685  56 YFDVAEGPVRLNALPSPRIIKthlplhllpkSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLL--KAPGTPFEF--VED 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534832  337 VQRLRGNCESIRLSAELGLRQpaWLRGRYMLVRYEDVARRPLQKAREMYSFAGIPLTPQ-----VEDWIQKNTQATRDSS 411
Cdd:pfam00685 132 FLNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEeldkiVKHLSFENMKGNPCLN 209

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 755534832  412 DVYSTQKNSS----EQFEKWRFSMPFKLAQVVQAACGPTMHLFG 451
Cdd:pfam00685 210 YSKLPKEVSPffrkGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
267-451 3.67e-27

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 109.35  E-value: 3.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534832  267 KDHVALKAVRIRQLEFLQPLV----------EDPRLDLRVIQLVRDPRAVLASRIVAFAGKYENwkKWLSEGQDQlsEDE 336
Cdd:pfam00685  56 YFDVAEGPVRLNALPSPRIIKthlplhllpkSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLL--KAPGTPFEF--VED 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534832  337 VQRLRGNCESIRLSAELGLRQpaWLRGRYMLVRYEDVARRPLQKAREMYSFAGIPLTPQ-----VEDWIQKNTQATRDSS 411
Cdd:pfam00685 132 FLNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLTEEeldkiVKHLSFENMKGNPCLN 209

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 755534832  412 DVYSTQKNSS----EQFEKWRFSMPFKLAQVVQAACGPTMHLFG 451
Cdd:pfam00685 210 YSKLPKEVSPffrkGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
Sulfotransfer_3 pfam13469
Sulfotransferase family;
293-394 2.15e-07

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 50.75  E-value: 2.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534832  293 DLRVIQLVRDPRAVLASRIVAFAGKYenwKKWLSEGQDQLSEDEVQRLRGNCESIRlsaelglrqPAWLR---GRYMLVR 369
Cdd:pfam13469  81 DAKFIHLHRDPVDTVISSYCSLFGFT---LSSYSTAFLRDIGLALARWSRAYERLM---------AARARvppGRFLDVR 148

                          90       100
                  ....*....|....*....|....*
gi 755534832  370 YEDVARRPLQKAREMYSFAGIPLTP 394
Cdd:pfam13469 149 YEDLVADPEGTLRRILEFLGLPWDD 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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