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Conserved domains on  [gi|767908145|ref|XP_011507384|]
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centromere protein F isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CENP-F_N pfam10481
Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound ...
 1-307 6.42e-136

Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound across the centromere as one of the proteins of the outer layer of the kinetochore. Most of the kinetochore/centromere functions appear to depend upon binding of the C-terminal par to f the molecule, whereas the N-terminal part, here, may be a cytoplasmic player in controlling the function of microtubules and dynein.


:

Pssm-ID: 463106 [Multi-domain]  Cd Length: 304  Bit Score: 427.70  E-value: 6.42e-136
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145     1 MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLE 80
Cdd:pfam10481    1 MSWAVEEWKEGLPTKALQKIQELESQLDKLKKERQQKQFQLESLEAALQKQKQKVENEKNEGSALKRENQSLMESCDNLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    81 KTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYS 160
Cdd:pfam10481   81 KSRQKISHDLQVKESQVNFLEGQLNSSKKQIEKLEQELKRYKSELERSQQALLAGDVSLQPCSTPQKSFATPLTPSQRHN 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   161 GSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRD 240
Cdd:pfam10481  161 DSKYEELQEKYNKEVEERKRLEAELKVLQVKKTNQTLPQSTVSHRDIARHQASSSVFPWQQEKTPSRQSSDAQETPLKRG 240

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767908145   241 FSASYFSGEQEVTPSRSTLqigKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKE 307
Cdd:pfam10481  241 FTASHFLWEHEETPSKRSQ---RSSSNSSLQSNSSSSQLMDQLKAQNQELRSRVSELELRLQAQEKD 304
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2131-2270 1.29e-42

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


:

Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 153.22  E-value: 1.29e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNE 2270
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2313-2452 3.19e-41

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


:

Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 149.37  E-value: 3.19e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2313 DEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRS 2392
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1983-2823 7.11e-28

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 124.40  E-value: 7.11e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1983 KMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLN 2062
Cdd:TIGR02168  233 RLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2063 KEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKL 2142
Cdd:TIGR02168  309 ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2143 KERERENDSLKDKVENLERELQMSEENQElvILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEK 2222
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRE--RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2223 QGQLSELDKLLSSFKSLLEEKEQaeiqikeeSKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2302
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQA--------RLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2303 IEK-LRARLEA----DEKKQLCVLQQLKESEhhadllKGRVENLERELEIARTNQEHAALEAENSKG------EVETLKA 2371
Cdd:TIGR02168  539 IEAaLGGRLQAvvveNLNAAKKAIAFLKQNE------LGRVTFLPLDSIKGTEIQGNDREILKNIEGflgvakDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2372 KIEGMTQSLRGLELDVVTIRSekenlTNELQKE---QERISEL--EIINSSFeNILQEKEQEKVQMKEKSStAMEMLQTQ 2446
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDN-----ALELAKKlrpGYRIVTLdgDLVRPGG-VITGGSAKTNSSILERRR-EIEELEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2447 LKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISR 2526
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2527 LKNQIQdqeqlvsklsqvegehqlwkeqnlELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMS 2606
Cdd:TIGR02168  766 LEERLE------------------------EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEELSgeknRLAGELqllleeiksSKYEVEIQTYREKLTSKEECLSSQKLE 2686
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIE----SLAAEI---------EELEELIEELESELEALLNERASLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2687 IDLLKSSKEELNNSLKAttqiLEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK-QLEEEKEILQKELSQLQAAQE 2765
Cdd:TIGR02168  889 LALLRSELEELSEELRE----LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQeRLSEEYSLTLEEAEALENKIE 964

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767908145  2766 KQKTGTvmDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2823
Cdd:TIGR02168  965 DDEEEA--RRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020
CENP-F_C_Rb_bdg pfam10490
Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2908-2954 3.96e-20

Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. This domain is at the very C-terminus of the C-terminal coiled-coil, and is one of the key Rb-binding domains.


:

Pssm-ID: 463111  Cd Length: 47  Bit Score: 85.58  E-value: 3.96e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 767908145  2908 PAEDTEGTEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSP 2954
Cdd:pfam10490    1 NRAEQDDEEFEPEGLPEVVQKGFADIPSGEVSPYILRRTTLQLRCSP 47
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 316-1160 5.39e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 5.39e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   316 QELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQAsTKYTALEQKLKKLTEDLSCQRQNAESARcsleqkiKEKEKE 395
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKA-ERYKELKAELRELELALLVLRLEELREE-------LEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLnqsqnfaEEMKAKNTSQETMLRDLQEKINQQENSLTLEK 555
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL-------EELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   556 LKLAVADLEKQRdcSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEyeelkeektlfscwksENEKLLTQMES 635
Cdd:TIGR02168  400 NEIERLEARLER--LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE----------------ELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   636 EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLaymeLQQKAEFsDQKHQ 715
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV----LSELISV-DEGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   716 KEIENMCLKTSQLTgQVEDLEHKLQ----LLSNEIMDKDRCYQDLHAEYE---SLRDLLKSKD------ASLVTNEDHQR 782
Cdd:TIGR02168  537 AAIEAALGGRLQAV-VVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEiqgNDREILKNIEgflgvaKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   783 SLLAF---------------DQQPAMHHSFANI------IGEQGSM--------------PSERSECRLEADQSPKNSAI 827
Cdd:TIGR02168  616 KALSYllggvlvvddldnalELAKKLRPGYRIVtldgdlVRPGGVItggsaktnssilerRREIEELEEKIEELEEKIAE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFvaetSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQLSKELTELEAEIEELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   988 QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEEtgnaYEDLSQKYKAAQEKNSKLECLLNECTSLCENR 1067
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE----LEELSEELRELESKRSELRRELEELREKLAQL 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDnQNNSKSEAGGLK----QEIMTLKEEQNKMQ 1143
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNlaaiEEYEELKERYDFLT 1006

                          890
                   ....*....|....*..
gi 767908145  1144 KEVNDLLQENEQLMKVM 1160
Cdd:TIGR02168 1007 AQKEDLTEAKETLEEAI 1023
PRK02224 super family cl32023
DNA double-strand break repair Rad50 ATPase;
1766-2194 1.14e-05

DNA double-strand break repair Rad50 ATPase;


The actual alignment was detected with superfamily member PRK02224:

Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1846 LEyfscdhqellqrvetseglnsDLEMHadkssREDIGDNVAKVNDSWKERFLDVENELSRIRsekasiEHEALyleadl 1925
Cdd:PRK02224  407 LG---------------------NAEDF-----LEELREERDELREREAELEATLRTARERVE------EAEAL------ 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1926 evvQTEKLCLEKDNENKQKVIVCL----EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEkTQELESHQSECLHC 2001
Cdd:PRK02224  449 ---LEAGKCPECGQPVEGSPHVETieedRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEEL 524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS- 2080
Cdd:PRK02224  525 IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2081 ESDYEKLNVSKALEAALVEkgEFALRLSSTQEEVHQLRRG-----IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDK 2155
Cdd:PRK02224  605 EDEIERLREKREALAELND--ERRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 767908145 2156 VENLERELQMSEENQELviLDA-ENSKAEVETLKTQIEEM 2194
Cdd:PRK02224  683 IGAVENELEELEELRER--REAlENRVEALEALYDEAEEL 720
 
Name Accession Description Interval E-value
CENP-F_N pfam10481
Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound ...
 1-307 6.42e-136

Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound across the centromere as one of the proteins of the outer layer of the kinetochore. Most of the kinetochore/centromere functions appear to depend upon binding of the C-terminal par to f the molecule, whereas the N-terminal part, here, may be a cytoplasmic player in controlling the function of microtubules and dynein.


Pssm-ID: 463106 [Multi-domain]  Cd Length: 304  Bit Score: 427.70  E-value: 6.42e-136
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145     1 MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLE 80
Cdd:pfam10481    1 MSWAVEEWKEGLPTKALQKIQELESQLDKLKKERQQKQFQLESLEAALQKQKQKVENEKNEGSALKRENQSLMESCDNLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    81 KTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYS 160
Cdd:pfam10481   81 KSRQKISHDLQVKESQVNFLEGQLNSSKKQIEKLEQELKRYKSELERSQQALLAGDVSLQPCSTPQKSFATPLTPSQRHN 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   161 GSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRD 240
Cdd:pfam10481  161 DSKYEELQEKYNKEVEERKRLEAELKVLQVKKTNQTLPQSTVSHRDIARHQASSSVFPWQQEKTPSRQSSDAQETPLKRG 240

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767908145   241 FSASYFSGEQEVTPSRSTLqigKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKE 307
Cdd:pfam10481  241 FTASHFLWEHEETPSKRSQ---RSSSNSSLQSNSSSSQLMDQLKAQNQELRSRVSELELRLQAQEKD 304
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2131-2270 1.29e-42

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 153.22  E-value: 1.29e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNE 2270
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2313-2452 3.19e-41

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 149.37  E-value: 3.19e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2313 DEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRS 2392
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1983-2823 7.11e-28

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 124.40  E-value: 7.11e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1983 KMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLN 2062
Cdd:TIGR02168  233 RLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2063 KEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKL 2142
Cdd:TIGR02168  309 ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2143 KERERENDSLKDKVENLERELQMSEENQElvILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEK 2222
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRE--RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2223 QGQLSELDKLLSSFKSLLEEKEQaeiqikeeSKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2302
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQA--------RLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2303 IEK-LRARLEA----DEKKQLCVLQQLKESEhhadllKGRVENLERELEIARTNQEHAALEAENSKG------EVETLKA 2371
Cdd:TIGR02168  539 IEAaLGGRLQAvvveNLNAAKKAIAFLKQNE------LGRVTFLPLDSIKGTEIQGNDREILKNIEGflgvakDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2372 KIEGMTQSLRGLELDVVTIRSekenlTNELQKE---QERISEL--EIINSSFeNILQEKEQEKVQMKEKSStAMEMLQTQ 2446
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDN-----ALELAKKlrpGYRIVTLdgDLVRPGG-VITGGSAKTNSSILERRR-EIEELEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2447 LKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISR 2526
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2527 LKNQIQdqeqlvsklsqvegehqlwkeqnlELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMS 2606
Cdd:TIGR02168  766 LEERLE------------------------EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEELSgeknRLAGELqllleeiksSKYEVEIQTYREKLTSKEECLSSQKLE 2686
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIE----SLAAEI---------EELEELIEELESELEALLNERASLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2687 IDLLKSSKEELNNSLKAttqiLEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK-QLEEEKEILQKELSQLQAAQE 2765
Cdd:TIGR02168  889 LALLRSELEELSEELRE----LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQeRLSEEYSLTLEEAEALENKIE 964

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767908145  2766 KQKTGTvmDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2823
Cdd:TIGR02168  965 DDEEEA--RRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020
CENP-F_C_Rb_bdg pfam10490
Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2908-2954 3.96e-20

Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. This domain is at the very C-terminus of the C-terminal coiled-coil, and is one of the key Rb-binding domains.


Pssm-ID: 463111  Cd Length: 47  Bit Score: 85.58  E-value: 3.96e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 767908145  2908 PAEDTEGTEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSP 2954
Cdd:pfam10490    1 NRAEQDDEEFEPEGLPEVVQKGFADIPSGEVSPYILRRTTLQLRCSP 47
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2053-2603 4.51e-20

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 98.57  E-value: 4.51e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2053 ELENQIAQlnKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSS---TQEEVHQLRRGIEKLRVRIE 2129
Cdd:PRK02224  191 QLKAQIEE--KEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEheeRREELETLEAEIEDLRETIA 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2130 ADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Cdd:PRK02224  269 ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQN---QLKELNEAVAALCGDQEIMKATE 2286
Cdd:PRK02224  349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDapvDLGNAEDFLEELREERDELRERE 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2287 QSLDPPIEEehqLRNSIEKLRARLEADeKKQLCVlQQLKESEH--HADLLKGRVENLERELEIARTnqehaaleaenskg 2364
Cdd:PRK02224  429 AELEATLRT---ARERVEEAEALLEAG-KCPECG-QPVEGSPHveTIEEDRERVEELEAELEDLEE-------------- 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2365 EVETLKAKIEGMTqSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEmlq 2444
Cdd:PRK02224  490 EVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEE--- 565

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2445 tQLKELNERVAALHNDQEACKAKEQNLSSQVECLEL--EKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDE 2522
Cdd:PRK02224  566 -EAEEAREEVAELNSKLAELKERIESLERIRTLLAAiaDAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFD 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2523 EiSRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS---KNASLQDTLEVLQSSYKNLEnELEL 2599
Cdd:PRK02224  645 E-ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElreRREALENRVEALEALYDEAE-ELES 722


                  ....
gi 767908145 2600 TKMD 2603
Cdd:PRK02224  723 MYGD 726
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1977-2519 4.58e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.47  E-value: 4.58e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1977 LDQLSEKMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2056
Cdd:COG1196   241 LEELEAELEELEAELEELEAE----LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2057 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQL 2136
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2137 HIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLT 2216
Cdd:COG1196   397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2217 KQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEE 2296
Cdd:COG1196   477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2297 HQLRNSIEKLRARLEAdeKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGM 2376
Cdd:COG1196   557 EVAAAAIEYLKAAKAG--RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2377 TQSL-RGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVA 2455
Cdd:COG1196   635 ALRRaVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767908145 2456 ALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEK 2519
Cdd:COG1196   715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 316-1160 5.39e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 5.39e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   316 QELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQAsTKYTALEQKLKKLTEDLSCQRQNAESARcsleqkiKEKEKE 395
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKA-ERYKELKAELRELELALLVLRLEELREE-------LEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLnqsqnfaEEMKAKNTSQETMLRDLQEKINQQENSLTLEK 555
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL-------EELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   556 LKLAVADLEKQRdcSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEyeelkeektlfscwksENEKLLTQMES 635
Cdd:TIGR02168  400 NEIERLEARLER--LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE----------------ELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   636 EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLaymeLQQKAEFsDQKHQ 715
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV----LSELISV-DEGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   716 KEIENMCLKTSQLTgQVEDLEHKLQ----LLSNEIMDKDRCYQDLHAEYE---SLRDLLKSKD------ASLVTNEDHQR 782
Cdd:TIGR02168  537 AAIEAALGGRLQAV-VVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEiqgNDREILKNIEgflgvaKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   783 SLLAF---------------DQQPAMHHSFANI------IGEQGSM--------------PSERSECRLEADQSPKNSAI 827
Cdd:TIGR02168  616 KALSYllggvlvvddldnalELAKKLRPGYRIVtldgdlVRPGGVItggsaktnssilerRREIEELEEKIEELEEKIAE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFvaetSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQLSKELTELEAEIEELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   988 QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEEtgnaYEDLSQKYKAAQEKNSKLECLLNECTSLCENR 1067
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE----LEELSEELRELESKRSELRRELEELREKLAQL 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDnQNNSKSEAGGLK----QEIMTLKEEQNKMQ 1143
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNlaaiEEYEELKERYDFLT 1006

                          890
                   ....*....|....*..
gi 767908145  1144 KEVNDLLQENEQLMKVM 1160
Cdd:TIGR02168 1007 AQKEDLTEAKETLEEAI 1023
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2208-2804 2.76e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 69.76  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2208 LRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQ 2287
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2288 SLDPPIEEEHQLRNSiEKLRARLEADEKKQLC---------VLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALE 2358
Cdd:pfam15921  342 DKIEELEKQLVLANS-ELTEARTERDQFSQESgnlddqlqkLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2359 AENSKGEVETLKAKIEGMTQSLRG-LELDVVTIRSEKENLtnelQKEQERISELEIINSSFENILQEKEQEKVQMkEKSS 2437
Cdd:pfam15921  421 LDDRNMEVQRLEALLKAMKSECQGqMERQMAAIQGKNESL----EKVSSLTAQLESTKEMLRKVVEELTAKKMTL-ESSE 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2438 TAMEMLQTQLKELNERVaalhndqEACKAKEQNLSSQVECleleKAQLLQGLDEAKNNYIVLQSSVNGLiqevedgKQKL 2517
Cdd:pfam15921  496 RTVSDLTASLQEKERAI-------EATNAEITKLRSRVDL----KLQELQHLKNEGDHLRNVQTECEAL-------KLQM 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2518 EKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQ-NLELRNLTVELeQKIQVLQSKNASLQDTLEVLQSsyknlenE 2596
Cdd:pfam15921  558 AEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQlEKEINDRRLEL-QEFKILKDKKDAKIRELEARVS-------D 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2597 LELTKMdkmsfvekvnKMTAKETELQREMHEMAQKTAELQEELSGEKNrlagELQLLLEEiksskYEVEIQTYREKLTSK 2676
Cdd:pfam15921  630 LELEKV----------KLVNAGSERLRAVKDIKQERDQLLNEVKTSRN----ELNSLSED-----YEVLKRNFRNKSEEM 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2677 EECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKE 2756
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEE 770

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 767908145  2757 LSQLqaAQEKQKTGTVMDTKVDELTTeIKELKETLEEKTKEADEYLDK 2804
Cdd:pfam15921  771 KNKL--SQELSTVATEKNKMAGELEV-LRSQERRLKEKVANMEVALDK 815
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 288-568 1.04e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  288 QELRNKINELELRLQGH-----EKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Cdd:COG1196   216 RELKEELKELEAELLLLklrelEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  363 KLKKLTEDLSCQRQNAESARcsleqKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKL 442
Cdd:COG1196   296 ELARLEQDIARLEERRRELE-----ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  443 TSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNF 522
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 767908145  523 AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRD 568
Cdd:COG1196   451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 360-588 5.29e-08

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 58.71  E-value: 5.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   360 LEQKLKKLTEDLSCQRQNAESAR--CSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQaknMHNVLQA 437
Cdd:pfam09726  400 LEQDIKKLKAELQASRQTEQELRsqISSLTSLERSLKSELGQLRQENDLLQTKLHNAVSAKQKDKQTVQQ---LEKRLKA 476

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   438 ELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE----LRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Cdd:pfam09726  477 EQEARASAEKQLAEEKKRKKEEEATAARAVALAAASRGEctesLKQRKRELESEIKKLTHDIKLKEEQIRELEIKVQELR 556

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   514 QCLNQSQNFAEEMKAkntsqetmLRDLQEKINQQENSLTLE-KLKL----AVADLEKQRDCSQDLLKKREHHIEQLNDKL 588
Cdd:pfam09726  557 KYKESEKDTEVLMSA--------LSAMQDKNQHLENSLSAEtRIKLdlfsALGDAKRQLEIAQGQIYQKDQEIKDLKQKI 628
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2034-2275 1.79e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2034 QEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQaRLSESDYEKLNVsKALEAALVEKGEFALRLSSTQEE 2113
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDV-ASAEREIAELEAELERLDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQ-MSEENQELVILDAENSKAEvETLKTQIE 2192
Cdd:COG4913   687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEaAEDLARLELRALLEERFAA-ALGDAVER 765

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2193 EMARSLkvfELDLVTLRSEKENLTKQIQEKQGQ----------------------LSELDKLLSS--------FKSLLEE 2242
Cdd:COG4913   766 ELRENL---EERIDALRARLNRAEEELERAMRAfnrewpaetadldadleslpeyLALLDRLEEDglpeyeerFKELLNE 842

                         250       260       270
                  ....*....|....*....|....*....|....
gi 767908145 2243 KEQAEI-QIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG4913   843 NSIEFVaDLLSKLRRAIREIKERIDPLNDSLKRI 876
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 20-362 9.35e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 9.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   20 IQELEGQLDKLKKEKQQ-----------RQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISH 88
Cdd:COG1196   195 LGELERQLEPLERQAEKaeryrelkeelKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   89 ELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLnpcntpqkifttpltpsqyysgskyEDLK 168
Cdd:COG1196   275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL-------------------------AELE 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  169 EKYNKEVEERKRLEAEVKALQAKKASQtlpQATMNHRDIARHQASSSVFSWQQEktpshlssnsqrtpiRRDFSASYFSG 248
Cdd:COG1196   330 EELEELEEELEELEEELEEAEEELEEA---EAELAEAEEALLEAEAELAEAEEE---------------LEELAEELLEA 391

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  249 EQEVTPSRSTLQIGKRDANSSFFdnsssphLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVE 328
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLE-------RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         330       340       350
                  ....*....|....*....|....*....|....
gi 767908145  329 LIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Cdd:COG1196   465 LAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
809-1235 5.26e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.37  E-value: 5.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  809 SERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQsfVAETSQRISKL 888
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE--YLDELREIEKR 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  889 QEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLkelQLLSETLSLEKKEMSSIISLNKRE 968
Cdd:PRK03918  316 LSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK---AKKEELERLKKRLTGLTPEKLEKE 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  969 IEELTQENGTLKEINASLNQEKMNLIQKsesfanyIDEREKSISELSdqyKQEKLILLQRCEETGNAYEDLSQKYKAaqe 1048
Cdd:PRK03918  393 LEELEKAKEEIEEEISKITARIGELKKE-------IKELKKAIEELK---KAKGKCPVCGRELTEEHRKELLEEYTA--- 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1049 KNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQefLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGL 1128
Cdd:PRK03918  460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKESE--LIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKL 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1129 KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCN---------FKPQMDLEVK 1199
Cdd:PRK03918  538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEpfyneylelKDAEKELERE 617

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 767908145 1200 EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQ 1235
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEKRLEELRKELEELE 653
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2271-2484 5.34e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2271 AVAALCGDQEIMKATEQSLDppieeehQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL----- 2345
Cdd:COG4942    11 LALAAAAQADAAAEAEAELE-------QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaalea 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2346 EIARTNQEHAALEAE-----------------NSKGEVETLKAKIEGMTQSLRGLELdVVTIRSEKENLTNELQKEQERI 2408
Cdd:COG4942    84 ELAELEKEIAELRAEleaqkeelaellralyrLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAEL 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145 2409 SELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQ 2484
Cdd:COG4942   163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1766-2194 1.14e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1846 LEyfscdhqellqrvetseglnsDLEMHadkssREDIGDNVAKVNDSWKERFLDVENELSRIRsekasiEHEALyleadl 1925
Cdd:PRK02224  407 LG---------------------NAEDF-----LEELREERDELREREAELEATLRTARERVE------EAEAL------ 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1926 evvQTEKLCLEKDNENKQKVIVCL----EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEkTQELESHQSECLHC 2001
Cdd:PRK02224  449 ---LEAGKCPECGQPVEGSPHVETieedRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEEL 524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS- 2080
Cdd:PRK02224  525 IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2081 ESDYEKLNVSKALEAALVEkgEFALRLSSTQEEVHQLRRG-----IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDK 2155
Cdd:PRK02224  605 EDEIERLREKREALAELND--ERRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 767908145 2156 VENLERELQMSEENQELviLDA-ENSKAEVETLKTQIEEM 2194
Cdd:PRK02224  683 IGAVENELEELEELRER--REAlENRVEALEALYDEAEEL 720
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1790-2057 2.73e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 2.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1790 IEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELE-KIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGlns 1868
Cdd:TIGR02169  746 LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEaRLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLN--- 822

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1869 dlEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVC 1948
Cdd:TIGR02169  823 --RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE 900

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1949 LEEELSVVTSERNQLRGEL-DTMSKKTTALDQLSEKMKEKTQELEShqSECLHCIQVAEAEVKEKTELLQTLSS------ 2021
Cdd:TIGR02169  901 LERKIEELEAQIEKKRKRLsELKAKLEALEEELSEIEDPKGEDEEI--PEEELSLEDVQAELQRVEEEIRALEPvnmlai 978

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 767908145  2022 -DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ 2057
Cdd:TIGR02169  979 qEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 1893-2018 6.73e-05

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 45.37  E-value: 6.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1893 WKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSK 1972
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 767908145  1973 KTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT 2018
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKT 126
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 18-371 7.85e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 7.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQV 97
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    98 NFQEGQLNSGKKQIEKLEQELKRCKSELERSQQaaqsadvslnpcntpqkifttpltpsqyysgsKYEDLKEKYNKEVEE 177
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEA--------------------------------QIEQLKEELKALREA 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   178 RKRLEAEVKALQAKKASQTLPQAtMNHRDIARHQASSSVFSWQQEKTPSHLSSNsqrtpirrdfSASYFSGEQEVTPSRS 257
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRERLE-SLERRIAATERRLEDLEEQIEELSEDIESL----------AAEIEELEELIEELES 873

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   258 TLQigkrdanSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIE-KEKVL 336
Cdd:TIGR02168  874 ELE-------ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLS 946

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 767908145   337 NKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDL 371
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2191-2441 2.60e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2191 IEEMARslkvfeLDLVTLRSEKENLTKQIQE----------KQGQ----------LSELDKLLSSFKSLLEEkeqAEIQI 2250
Cdd:PRK05771    3 PVRMKK------VLIVTLKSYKDEVLEALHElgvvhiedlkEELSnerlrklrslLTKLSEALDKLRSYLPK---LNPLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2251 KEESKTAVEMLQNQLKELNEAVAALcgdqeimkatEQSLDPPIEEEHQLRNSIEKLRARLEADEK-KQLCVLQQLKESEH 2329
Cdd:PRK05771   74 EEKKKVSVKSLEELIKDVEEELEKI----------EKEIKELEEEISELENEIKELEQEIERLEPwGNFDLDLSLLLGFK 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2330 HADLLKGRVeNLERELEIARTNQEHAALEAENSKGE----VETLKAKIEGMTQSLRGLELDVVTIrSEKENLTNELQKEQ 2405
Cdd:PRK05771  144 YVSVFVGTV-PEDKLEELKLESDVENVEYISTDKGYvyvvVVVLKELSDEVEEELKKLGFERLEL-EEEGTPSELIREIK 221

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 767908145 2406 ERI----SELEIINSSFENILQEKEQEKVQMKEKSSTAME 2441
Cdd:PRK05771  222 EELeeieKERESLLEELKELAKKYLEELLALYEYLEIELE 261
PRK12704 PRK12704
phosphodiesterase; Provisional
 44-201 7.07e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 7.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   44 LEAALQKQKQKVENEKTEGTNLKRE-----NQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQEL 118
Cdd:PRK12704   33 IKEAEEEAKRILEEAKKEAEAIKKEalleaKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEEL 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  119 KRCKSELERSQQAAQSADVSLnpcntpQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEER---------KRLEAEVKALQ 189
Cdd:PRK12704  113 EKKEKELEQKQQELEKKEEEL------EELIEEQLQELERISGLTAEEAKEILLEKVEEEarheaavliKEIEEEAKEEA 186

                         170
                  ....*....|..
gi 767908145  190 AKKASQTLPQAT 201
Cdd:PRK12704  187 DKKAKEILAQAI 198
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1949-2066 8.02e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 8.02e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKtelLQTLSSDVSELLK 2028
Cdd:smart00787  149 LDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKEK---LKKLLQEIMIKVK 225

                            90       100       110
                    ....*....|....*....|....*....|....*...
gi 767908145   2029 DKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKE 2066
Cdd:smart00787  226 KLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLE 263
pepcterm_ChnLen TIGR03007
polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this ...
 2215-2442 9.57e-03

polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this protein family belong to the family of polysaccharide chain length determinant proteins (pfam02706). All are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria, and are found near the epsH homolog that is the putative exosortase gene. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274386 [Multi-domain]  Cd Length: 498  Bit Score: 41.58  E-value: 9.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2215 LTKQIQEKQGQLSELDKLLSSFKSlleEK----EQAEIQIKEESKTAVEMLQNQLKELNEAVAAL------CGDQEIMKA 2284
Cdd:TIGR03007  166 IDEQIKTYEKKLEAAENRLKAFKQ---ENggilPDQEGDYYSEISEAQEELEAARLELNEAIAQRdalkrqLGGEEPVLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2285 TEQSLDPPieeehQLRNSIEKLRARLEAdekkqlcvlQQLKESEHHADllkgrVENLERELEIARTNQEHAALEAENSKG 2364
Cdd:TIGR03007  243 AGSSVANS-----ELDGRIEALEKQLDA---------LRLRYTDKHPD-----VIATKREIAQLEEQKEEEGSAKNGGPE 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEK------VQMKEKSST 2438
Cdd:TIGR03007  304 RGEIANPVYQQLQIELAEAEAEIASLEARVAELTARIERLESLLRTIPEVEAELTQLNRDYEVNKsnyeqlLTRRESAEV 383


                   ....
gi 767908145  2439 AMEM 2442
Cdd:TIGR03007  384 SKQM 387
 
Name Accession Description Interval E-value
CENP-F_N pfam10481
Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound ...
 1-307 6.42e-136

Cenp-F N-terminal domain; Mitosin or centromere-associated protein-F (Cenp-F) is found bound across the centromere as one of the proteins of the outer layer of the kinetochore. Most of the kinetochore/centromere functions appear to depend upon binding of the C-terminal par to f the molecule, whereas the N-terminal part, here, may be a cytoplasmic player in controlling the function of microtubules and dynein.


Pssm-ID: 463106 [Multi-domain]  Cd Length: 304  Bit Score: 427.70  E-value: 6.42e-136
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145     1 MSWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLE 80
Cdd:pfam10481    1 MSWAVEEWKEGLPTKALQKIQELESQLDKLKKERQQKQFQLESLEAALQKQKQKVENEKNEGSALKRENQSLMESCDNLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    81 KTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYS 160
Cdd:pfam10481   81 KSRQKISHDLQVKESQVNFLEGQLNSSKKQIEKLEQELKRYKSELERSQQALLAGDVSLQPCSTPQKSFATPLTPSQRHN 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   161 GSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRD 240
Cdd:pfam10481  161 DSKYEELQEKYNKEVEERKRLEAELKVLQVKKTNQTLPQSTVSHRDIARHQASSSVFPWQQEKTPSRQSSDAQETPLKRG 240

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767908145   241 FSASYFSGEQEVTPSRSTLqigKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKE 307
Cdd:pfam10481  241 FTASHFLWEHEETPSKRSQ---RSSSNSSLQSNSSSSQLMDQLKAQNQELRSRVSELELRLQAQEKD 304
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2131-2270 1.29e-42

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 153.22  E-value: 1.29e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNE 2270
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2313-2452 3.19e-41

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 149.37  E-value: 3.19e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2313 DEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRS 2392
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKTAVEMLQTQLKELNE 140
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1983-2823 7.11e-28

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 124.40  E-value: 7.11e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1983 KMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLN 2062
Cdd:TIGR02168  233 RLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2063 KEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKL 2142
Cdd:TIGR02168  309 ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2143 KERERENDSLKDKVENLERELQMSEENQElvILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEK 2222
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRE--RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2223 QGQLSELDKLLSSFKSLLEEKEQaeiqikeeSKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2302
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQA--------RLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2303 IEK-LRARLEA----DEKKQLCVLQQLKESEhhadllKGRVENLERELEIARTNQEHAALEAENSKG------EVETLKA 2371
Cdd:TIGR02168  539 IEAaLGGRLQAvvveNLNAAKKAIAFLKQNE------LGRVTFLPLDSIKGTEIQGNDREILKNIEGflgvakDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2372 KIEGMTQSLRGLELDVVTIRSekenlTNELQKE---QERISEL--EIINSSFeNILQEKEQEKVQMKEKSStAMEMLQTQ 2446
Cdd:TIGR02168  613 KLRKALSYLLGGVLVVDDLDN-----ALELAKKlrpGYRIVTLdgDLVRPGG-VITGGSAKTNSSILERRR-EIEELEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2447 LKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISR 2526
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2527 LKNQIQdqeqlvsklsqvegehqlwkeqnlELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMS 2606
Cdd:TIGR02168  766 LEERLE------------------------EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEELSgeknRLAGELqllleeiksSKYEVEIQTYREKLTSKEECLSSQKLE 2686
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIE----SLAAEI---------EELEELIEELESELEALLNERASLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2687 IDLLKSSKEELNNSLKAttqiLEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK-QLEEEKEILQKELSQLQAAQE 2765
Cdd:TIGR02168  889 LALLRSELEELSEELRE----LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQeRLSEEYSLTLEEAEALENKIE 964

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767908145  2766 KQKTGTvmDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2823
Cdd:TIGR02168  965 DDEEEA--RRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020
CENP-F_C_Rb_bdg pfam10490
Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 2908-2954 3.96e-20

Rb-binding domain of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. This domain is at the very C-terminus of the C-terminal coiled-coil, and is one of the key Rb-binding domains.


Pssm-ID: 463111  Cd Length: 47  Bit Score: 85.58  E-value: 3.96e-20
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 767908145  2908 PAEDTEGTEFEPEGLPEVVKKGFADIPTGKTSPYILRRTTMATRTSP 2954
Cdd:pfam10490    1 NRAEQDDEEFEPEGLPEVVQKGFADIPSGEVSPYILRRTTLQLRCSP 47
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2053-2603 4.51e-20

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 98.57  E-value: 4.51e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2053 ELENQIAQlnKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSS---TQEEVHQLRRGIEKLRVRIE 2129
Cdd:PRK02224  191 QLKAQIEE--KEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEheeRREELETLEAEIEDLRETIA 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2130 ADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Cdd:PRK02224  269 ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQN---QLKELNEAVAALCGDQEIMKATE 2286
Cdd:PRK02224  349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDapvDLGNAEDFLEELREERDELRERE 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2287 QSLDPPIEEehqLRNSIEKLRARLEADeKKQLCVlQQLKESEH--HADLLKGRVENLERELEIARTnqehaaleaenskg 2364
Cdd:PRK02224  429 AELEATLRT---ARERVEEAEALLEAG-KCPECG-QPVEGSPHveTIEEDRERVEELEAELEDLEE-------------- 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2365 EVETLKAKIEGMTqSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEmlq 2444
Cdd:PRK02224  490 EVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEE--- 565

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2445 tQLKELNERVAALHNDQEACKAKEQNLSSQVECLEL--EKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDE 2522
Cdd:PRK02224  566 -EAEEAREEVAELNSKLAELKERIESLERIRTLLAAiaDAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFD 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2523 EiSRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS---KNASLQDTLEVLQSSYKNLEnELEL 2599
Cdd:PRK02224  645 E-ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElreRREALENRVEALEALYDEAE-ELES 722


                  ....
gi 767908145 2600 TKMD 2603
Cdd:PRK02224  723 MYGD 726
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1977-2519 4.58e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 98.47  E-value: 4.58e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1977 LDQLSEKMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2056
Cdd:COG1196   241 LEELEAELEELEAELEELEAE----LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2057 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQL 2136
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2137 HIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLT 2216
Cdd:COG1196   397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2217 KQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEE 2296
Cdd:COG1196   477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2297 HQLRNSIEKLRARLEAdeKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGM 2376
Cdd:COG1196   557 EVAAAAIEYLKAAKAG--RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2377 TQSL-RGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVA 2455
Cdd:COG1196   635 ALRRaVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767908145 2456 ALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEK 2519
Cdd:COG1196   715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1766-2491 5.22e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.12  E-value: 5.22e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1846 LEYFSCDHQELLQRVETS----EGLNSDL--EMHADKSSREDIGDNVAKVNDSWKERfldvENELSRIRS-EKASIEHEA 1918
Cdd:TIGR02168  360 LEELEAELEELESRLEELeeqlETLRSKVaqLELQIASLNNEIERLEARLERLEDRR----ERLQQEIEElLKKLEEAEL 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1919 LYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQ---ELESHQ 1995
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEgvkALLKNQ 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1996 SECLHCIQVA----EAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQI-AQLNKEKELLVK 2070
Cdd:TIGR02168  516 SGLSGILGVLseliSVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKgTEIQGNDREILK 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2071 ESESLQARLSESDYEKLNVSKALEAAL-----VEKGEFALRLSS---------TQEEVHQLRRGieklrVRIEADEKKQL 2136
Cdd:TIGR02168  596 NIEGFLGVAKDLVKFDPKLRKALSYLLggvlvVDDLDNALELAKklrpgyrivTLDGDLVRPGG-----VITGGSAKTNS 670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2137 HIAEK---LKERERENDSLKDKVENLERELQMSEENQelvildaENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE 2213
Cdd:TIGR02168  671 SILERrreIEELEEKIEELEEKIAELEKALAELRKEL-------EELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2214 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLdppi 2293
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA---- 819

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2294 eeeHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKI 2373
Cdd:TIGR02168  820 ---ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL 896

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2374 EGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEK----EQEKVQMKEKSSTAMEMLQTQLKE 2449
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR 976

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 767908145  2450 LNERVAALHN-------DQEACKAKEQNLSSQVECLELEKAQLLQGLDE 2491
Cdd:TIGR02168  977 LENKIKELGPvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2021-2803 1.05e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 94.36  E-value: 1.05e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2021 SDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESEsLQARLSEsdYEKLNVSKALEAALVEK 2100
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQA-LLKEKRE--YEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2101 GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKK---------------QLHIAEKLKERERENDSLKDKVENLERELQM 2165
Cdd:TIGR02169  240 EAIERQLASLEEELEKLTEEISELEKRLEEIEQLleelnkkikdlgeeeQLRVKEKIGELEAEIASLERSIAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2166 SEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQgqlSELDKLLSSFKSLLEEKEQ 2245
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD---KEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2246 AEIQIkEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEehqLRNSIEKLRARLEADEKKQLCVLQQLK 2325
Cdd:TIGR02169  397 LKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKED---KALEIKKQEWKLEQLAADLSKYEQELY 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2326 ESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGL----ELDVVTIRSEKENLTNEL 2401
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLgsvgERYATAIEVAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2402 QKEQERISELEIinssfeNILQEKEQ--------EKVQMKEKSSTAMEM-----LQTQLKELNERVAA----------LH 2458
Cdd:TIGR02169  553 VVEDDAVAKEAI------ELLKRRKAgratflplNKMRDERRDLSILSEdgvigFAVDLVEFDPKYEPafkyvfgdtlVV 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2459 NDQEAckAKEQNLSSQVECLE---LEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKkdeEISRLKNQIQDQE 2535
Cdd:TIGR02169  627 EDIEA--ARRLMGKYRMVTLEgelFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKR---ELSSLQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2536 QLVSKLSQVEGEHQlwkeqnlelrNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKmdkmsfvEKVNKMT 2615
Cdd:TIGR02169  702 NRLDELSQELSDAS----------RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK-------SELKELE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2616 AKETELQREMHEMAQKTAELQEELSGEKNRlagELQLLLEEIKSskyevEIQTYREKLTSKEECLSSQKLEIDLLKSSKE 2695
Cdd:TIGR02169  765 ARIEELEEDLHKLEEALNDLEARLSHSRIP---EIQAELSKLEE-----EVSRIEARLREIEQKLNRLTLEKEYLEKEIQ 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2696 ELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKtgtvmdT 2775
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE------A 910

                          810       820
                   ....*....|....*....|....*...
gi 767908145  2776 KVDELTTEIKELKETLEEKTKEADEYLD 2803
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEELSEIED 938
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2033-2659 1.14e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.85  E-value: 1.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2033 LQEKLQslEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDyeklnvsKALEAALVEKGEFALRLSSTQE 2112
Cdd:COG1196   218 LKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE-------AELEELRLELEELELELEEAQA 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2113 EVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2192
Cdd:COG1196   289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2193 EMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2272
Cdd:COG1196   369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2273 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLcVLQQLKESEHHADLLKGRVENLERELEIARTNQ 2352
Cdd:COG1196   449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL-LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2353 EHAALEAenskgEVETlkakiegmtqslrglELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQM 2432
Cdd:COG1196   528 VLIGVEA-----AYEA---------------ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAA 587

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2433 KEKSSTAMEMLqtqlkelnERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVED 2512
Cdd:COG1196   588 LAAALARGAIG--------AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2513 GKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKN 2592
Cdd:COG1196   660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE 739

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767908145 2593 LENELELTKMDkmsFVEKVNKMTAKETELQREMHEMAQKTAEL----------QEELSGEKNRLAGELQLLLEEIKS 2659
Cdd:COG1196   740 ELLEEEELLEE---EALEELPEPPDLEELERELERLEREIEALgpvnllaieeYEELEERYDFLSEQREDLEEARET 813
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1900-2761 1.45e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 93.59  E-value: 1.45e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1900 VENELSRIRSEKA-SIEHEALYL---EADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKtt 1975
Cdd:TIGR02169  196 KRQQLERLRREREkAERYQALLKekrEYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQL-- 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1976 aLDQLSEKMKEKTQElESHQseclhcIQVAEAEVKEKTELLQTLSSDVSELLKDkthLQEKLQSLEKDSQALSLTKCELE 2055
Cdd:TIGR02169  274 -LEELNKKIKDLGEE-EQLR------VKEKIGELEAEIASLERSIAEKERELED---AEERLAKLEAEIDKLLAEIEELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2056 NQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQ 2135
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2136 LHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLvtlrSEKENL 2215
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL----AEAEAQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2216 TKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEM-----LQNQLKElNEAVAALCgdqeIMKATEQSLD 2290
Cdd:TIGR02169  499 ARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVaagnrLNNVVVE-DDAVAKEA----IELLKRRKAG 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2291 P----PIEEEHQLRNSIEKLRAR---------LEADEKKQLCVLQQLKESehhadLLKGRVENLERELEIARTnqehAAL 2357
Cdd:TIGR02169  574 RatflPLNKMRDERRDLSILSEDgvigfavdlVEFDPKYEPAFKYVFGDT-----LVVEDIEAARRLMGKYRM----VTL 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2358 EaenskGEVETLKAKIEGMTQSLRGLELDVvtiRSEKEnltnELQKEQERISELEIinsSFENILQEKEQEKVQMKEKSS 2437
Cdd:TIGR02169  645 E-----GELFEKSGAMTGGSRAPRGGILFS---RSEPA----ELQRLRERLEGLKR---ELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2438 tamemlqtQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEkaqlLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKL 2517
Cdd:TIGR02169  710 --------ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED----LSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2518 EKKDEEISRLKNQiqdqeqlvSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQvlqsknaSLQDTLEVLQSSYKNLENEL 2597
Cdd:TIGR02169  778 EEALNDLEARLSH--------SRIPEIQAELSKLEEEVSRIEARLREIEQKLN-------RLTLEKEYLEKEIQELQEQR 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2598 ELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSG-EKNRLAGELQLLLEEIKSSKYEVEIQTYREKLTSK 2676
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDlKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2677 EECLSSQKLEIDLLKSSKEELnNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKE 2756
Cdd:TIGR02169  923 KAKLEALEEELSEIEDPKGED-EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEE 1001


                   ....*
gi 767908145  2757 LSQLQ 2761
Cdd:TIGR02169 1002 RKAIL 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1950-2728 2.54e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.82  E-value: 2.54e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1950 EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKE--------KTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Cdd:TIGR02169  186 IERLDLIIDEKRQQLERLRREREKAERYQALLKEKREyegyellkEKEALERQKEAIERQLASLEEELEKLTEEISELEK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2022 DVSELLKDKTHLQEKLQSLEKDSQALSLTKC-ELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEK 2100
Cdd:TIGR02169  266 RLEEIEQLLEELNKKIKDLGEEEQLRVKEKIgELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2101 GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENS 2180
Cdd:TIGR02169  346 EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2181 KAEVETLKTQI-------EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKE---QAEIQI 2250
Cdd:TIGR02169  426 NAAIAGIEAKIneleeekEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEaqaRASEER 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2251 KEESKTAVEMLQNQLKELNEAVAALCG-DQEIMKATEQSLDPP-----IEEEHQLRNSIEKLRAR--------------- 2309
Cdd:TIGR02169  506 VRGGRAVEEVLKASIQGVHGTVAQLGSvGERYATAIEVAAGNRlnnvvVEDDAVAKEAIELLKRRkagratflplnkmrd 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2310 --------------------LEADEKKQLCVLQQLK-----ESEHHADLLKGRVENLERELEI---------ARTNQEHA 2355
Cdd:TIGR02169  586 errdlsilsedgvigfavdlVEFDPKYEPAFKYVFGdtlvvEDIEAARRLMGKYRMVTLEGELfeksgamtgGSRAPRGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2356 ALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiinSSFENILQEKEQEKVQMKEk 2435
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE---KEIEQLEQEEEKLKERLEE- 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2436 sstamemLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKnnyivlqssvnglIQEVEDGKQ 2515
Cdd:TIGR02169  742 -------LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR-------------IPEIQAELS 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2516 KLEkkdEEISRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYK 2591
Cdd:TIGR02169  802 KLE---EEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2592 NLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKYEVEIQTYRE 2671
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQA 958

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767908145  2672 KLTSKEECLSS----QKLEIDLLKSSKEELnNSLKATTQILEELKKTKMDNLKYVNQLKKE 2728
Cdd:TIGR02169  959 ELQRVEEEIRAlepvNMLAIQEYEEVLKRL-DELKEKRAKLEEERKAILERIEEYEKKKRE 1018
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2141-2820 2.55e-16

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 85.84  E-value: 2.55e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2141 KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQ 2220
Cdd:TIGR04523   34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIK 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2221 EKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESK---TAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEH 2297
Cdd:TIGR04523  114 NDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKkkeKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIK 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2298 QLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTnqehaalEAENSKGEVETLKAKIEGMT 2377
Cdd:TIGR04523  194 NKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTT-------EISNTQTQLNQLKDEQNKIK 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2378 QSLRGLELDVVTIRSEKENLTNELQKEQERISEL-----EIINSSFENILQEKEQEKVQmkeksstamemLQTQLKELNE 2452
Cdd:TIGR04523  267 KQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLnnqkeQDWNKELKSELKNQEKKLEE-----------IQNQISQNNK 335

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2453 RVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQ 2532
Cdd:TIGR04523  336 IISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIK 415

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2533 DQEQLVSKLSQvegEHQLWKEQNLELRNLTVELEQKIQV-------LQSKNASLQDTLEVLQSSYKNLENELELTKMDKM 2605
Cdd:TIGR04523  416 KLQQEKELLEK---EIERLKETIIKNNSEIKDLTNQDSVkeliiknLDNTRESLETQLKVLSRSINKIKQNLEQKQKELK 492

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2606 SFVEKVNKMTAKETELQREMHEMAQKTAEL---QEELSGEKNRLAGELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSS 2682
Cdd:TIGR04523  493 SKEKELKKLNEEKKELEEKVKDLTKKISSLkekIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEE 572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2683 QKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQA 2762
Cdd:TIGR04523  573 LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 767908145  2763 AQEKQK-TGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKE 2820
Cdd:TIGR04523  653 TIKEIRnKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRMIRIKDLPKLEE 711
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2105-2793 3.33e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.68  E-value: 3.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2105 LRLSSTQEE-------VHQLRRGIEKLRvrieaDEKKQLHIAEKLKE--RERENDSLKDKVENLERELQMSEENQELVIL 2175
Cdd:COG1196   179 RKLEATEENlerlediLGELERQLEPLE-----RQAEKAERYRELKEelKELEAELLLLKLRELEAELEELEAELEELEA 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2176 DAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESK 2255
Cdd:COG1196   254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2256 TAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLK 2335
Cdd:COG1196   334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2336 GRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiin 2415
Cdd:COG1196   414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA--- 490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2416 ssfENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKE-------------QNLSSQVECLELEK 2482
Cdd:COG1196   491 ---ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALeaalaaalqnivvEDDEVAAAAIEYLK 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2483 AQLL-----QGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLknqiqdqeqlvskLSQVEGEHQLWKEQNLE 2557
Cdd:COG1196   568 AAKAgratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV-------------LGDTLLGRTLVAARLEA 634

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2558 LRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELtkmdkmsfvEKVNKMTAKETELQREMHEMAQKTAELQE 2637
Cdd:COG1196   635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE---------AEAELEELAERLAEEELELEEALLAEEEE 705

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2638 ELSGEKNRLAGELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNnslkattQILEELKKtKMD 2717
Cdd:COG1196   706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE-------RELERLER-EIE 777

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2718 NLKYVN-----QLKKENERAQGkmklliksckqLEEEKEILQKELSQLQAAqekqktgtvmdtkVDELTTEIKE-LKETL 2791
Cdd:COG1196   778 ALGPVNllaieEYEELEERYDF-----------LSEQREDLEEARETLEEA-------------IEEIDRETRErFLETF 833


                  ..
gi 767908145 2792 EE 2793
Cdd:COG1196   834 DA 835
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2186-2798 4.59e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 4.59e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2186 TLKTQIEEMARSLKVFELDLvtLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEEsktaVEMLQNQL 2265
Cdd:COG1196   217 ELKEELKELEAELLLLKLRE--LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE----LEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2266 KELNEAVAALCGDQEIMKATEQSLDppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL 2345
Cdd:COG1196   291 YELLAELARLEQDIARLEERRRELE---ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2346 EIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEK 2425
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2426 EQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVEcLELEKAQLLQGLDEAKNnyIVLQSSVNG 2505
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE-AEADYEGFLEGVKAALL--LAGLRGLAG 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2506 LIQEVEDGKQKLEKKDEE--ISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTV----ELEQKIQVLQSKNASL 2579
Cdd:COG1196   525 AVAVLIGVEAAYEAALEAalAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAraalAAALARGAIGAAVDLV 604

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2580 QDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQktAELQEELSGEKNRLAGELQLLLEEIKS 2659
Cdd:COG1196   605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG--GSAGGSLTGGSRRELLAALLEAEAELE 682

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2660 SKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLkyvnQLKKENERAQGKMKLL 2739
Cdd:COG1196   683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL----EEEELLEEEALEELPE 758

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767908145 2740 IKSCKQLEEEKEILQKELSQL----------QAAQEKQKTGtvMDTKVDELTTEIKELKETLEEKTKEA 2798
Cdd:COG1196   759 PPDLEELERELERLEREIEALgpvnllaieeYEELEERYDF--LSEQREDLEEARETLEEAIEEIDRET 825
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1786-2491 1.40e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.50  E-value: 1.40e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1786 LLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEkleyfscdhQELLQRVETSEG 1865
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---------EEQLRVKEKIGE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1866 LNSDLE-----MHADKSSREDIGDNVAKVN---DSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEK 1937
Cdd:TIGR02169  299 LEAEIAslersIAEKERELEDAEERLAKLEaeiDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1938 DNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQ 2017
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2018 TLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ----------------------------IAQLNKEKELLV 2069
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQaraseervrggraveevlkasiqgvhgtVAQLGSVGERYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2070 KESES-----LQARLSESD----------------------YEKLNVSKALEAALVEKG-------------------EF 2103
Cdd:TIGR02169  539 TAIEVaagnrLNNVVVEDDavakeaiellkrrkagratflpLNKMRDERRDLSILSEDGvigfavdlvefdpkyepafKY 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2104 ALRLSSTQEEVHQLRRGIEKLR-VRIEAD--EKKQLHIAEKLKERERENDSLKDKvenlERELQMSEENQELvildaens 2180
Cdd:TIGR02169  619 VFGDTLVVEDIEAARRLMGKYRmVTLEGElfEKSGAMTGGSRAPRGGILFSRSEP----AELQRLRERLEGL-------- 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2181 KAEVETLKTQIEEMARSLKvfeldlvTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEqAEIQIKEESKTAVE- 2259
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLD-------ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-EDLSSLEQEIENVKs 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2260 MLQNQLKELNEAVAALCGDQEIMKATEQSLDP-PIEEEHQLRNSIEKLRAR-------LEADEKKQLCVLQQLKESEHHA 2331
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHsRIPEIQAELSKLEEEVSRiearlreIEQKLNRLTLEKEYLEKEIQEL 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2332 ----DLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQER 2407
Cdd:TIGR02169  839 qeqrIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2408 ISELEIINSSFENILQEKEQEKVQMKEKSSTAM--EMLQTQLKELNERVAALH-------NDQEACKAKEQNLSSQVECL 2478
Cdd:TIGR02169  919 LSELKAKLEALEEELSEIEDPKGEDEEIPEEELslEDVQAELQRVEEEIRALEpvnmlaiQEYEEVLKRLDELKEKRAKL 998

                          810
                   ....*....|...
gi 767908145  2479 ELEKAQLLQGLDE 2491
Cdd:TIGR02169  999 EEERKAILERIEE 1011
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2063-2674 4.28e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 78.95  E-value: 4.28e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2063 KEKELLVKESESLQARLSESDYE---KLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIA 2139
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKEleeVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2140 EKLKERERENDSLKDKVENLERELQMSEENQELVIL---------DAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:PRK03918  259 EKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyiklsefyeEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLD 2290
Cdd:PRK03918  339 RLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2291 PPIEEehqLRNSIEKLR----------ARLEADEKKQLC---------VLQQLKESEHHADLLKGRVENLERELEIAR-- 2349
Cdd:PRK03918  419 KEIKE---LKKAIEELKkakgkcpvcgRELTEEHRKELLeeytaelkrIEKELKEIEEKERKLRKELRELEKVLKKESel 495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2350 -----TNQEHAALEAENSKGEVETLKAKiegmTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE 2424
Cdd:PRK03918  496 iklkeLAEQLKELEEKLKKYNLEELEKK----AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEE 571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2425 KEQEKVQMKEKSSTAMEMLQTQLKELNErvaaLHNDQEACKAKEQNLSSQVECLELEKaqllqgldeaknnyivlqssvn 2504
Cdd:PRK03918  572 LAELLKELEELGFESVEELEERLKELEP----FYNEYLELKDAEKELEREEKELKKLE---------------------- 625

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2505 gliQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSklsqvegehqlwKEQNLELRNLTVELEQKIQVLQSKNASLQDTLE 2584
Cdd:PRK03918  626 ---EELDKAFEELAETEKRLEELRKELEELEKKYS------------EEEYEELREEYLELSRELAGLRAELEELEKRRE 690

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2585 VLQSSYKNLENELELTKMDKMSfVEKVNKMTAKETELQREMHEMaqkTAELQEELSGEKNRLAGElqlLLEEIKSSKY-E 2663
Cdd:PRK03918  691 EIKKTLEKLKEELEEREKAKKE-LEKLEKALERVEELREKVKKY---KALLKERALSKVGEIASE---IFEELTEGKYsG 763

                         650
                  ....*....|.
gi 767908145 2664 VEIQTYREKLT 2674
Cdd:PRK03918  764 VRVKAEENKVK 774
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 316-1160 5.39e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 5.39e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   316 QELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQAsTKYTALEQKLKKLTEDLSCQRQNAESARcsleqkiKEKEKE 395
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKA-ERYKELKAELRELELALLVLRLEELREE-------LEELQE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKEN 475
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   476 ELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLnqsqnfaEEMKAKNTSQETMLRDLQEKINQQENSLTLEK 555
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL-------EELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   556 LKLAVADLEKQRdcSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEyeelkeektlfscwksENEKLLTQMES 635
Cdd:TIGR02168  400 NEIERLEARLER--LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE----------------ELQEELERLEE 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   636 EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLaymeLQQKAEFsDQKHQ 715
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV----LSELISV-DEGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   716 KEIENMCLKTSQLTgQVEDLEHKLQ----LLSNEIMDKDRCYQDLHAEYE---SLRDLLKSKD------ASLVTNEDHQR 782
Cdd:TIGR02168  537 AAIEAALGGRLQAV-VVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEiqgNDREILKNIEgflgvaKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   783 SLLAF---------------DQQPAMHHSFANI------IGEQGSM--------------PSERSECRLEADQSPKNSAI 827
Cdd:TIGR02168  616 KALSYllggvlvvddldnalELAKKLRPGYRIVtldgdlVRPGGVItggsaktnssilerRREIEELEEKIEELEEKIAE 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFvaetSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQLSKELTELEAEIEELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   988 QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEEtgnaYEDLSQKYKAAQEKNSKLECLLNECTSLCENR 1067
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE----LEELSEELRELESKRSELRRELEELREKLAQL 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDnQNNSKSEAGGLK----QEIMTLKEEQNKMQ 1143
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNlaaiEEYEELKERYDFLT 1006

                          890
                   ....*....|....*..
gi 767908145  1144 KEVNDLLQENEQLMKVM 1160
Cdd:TIGR02168 1007 AQKEDLTEAKETLEEAI 1023
PTZ00121 PTZ00121
MAEBL; Provisional
 2035-2800 1.12e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.87  E-value: 1.12e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2035 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGefALRLSSTQEEV 2114
Cdd:PTZ00121 1203 EAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQ--AAIKAEEARKA 1280

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2115 HQLRRGIEKLRVR--IEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2192
Cdd:PTZ00121 1281 DELKKAEEKKKADeaKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2193 EMARSLKVFELDLVTLRSEKENLTKQIQEKQgQLSELDKllssfKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2272
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKK-KADEAKK-----KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2273 AALCGDQEIMKATEqsLDPPIEEEHQLRNSIEKLRARLEADEKKqlcvlqqlKESEHhadllKGRVENLERELEIARTNQ 2352
Cdd:PTZ00121 1435 EAKKKAEEAKKADE--AKKKAEEAKKAEEAKKKAEEAKKADEAK--------KKAEE-----AKKADEAKKKAEEAKKKA 1499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2353 EHAALEAENSKGEVETLKAKIEGMTQSLRgleldvvtiRSEKENLTNELQKEQERISELEIINSsfENILQEKEQEKVQM 2432
Cdd:PTZ00121 1500 DEAKKAAEAKKKADEAKKAEEAKKADEAK---------KAEEAKKADEAKKAEEKKKADELKKA--EELKKAEEKKKAEE 1568

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2433 KEKSSTAMEMLQTQLKELnervaalhndQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSvngliQEVED 2512
Cdd:PTZ00121 1569 AKKAEEDKNMALRKAEEA----------KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA-----EEEKK 1633

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2513 GKQKLEKKDEEISRLKNQIQDQEQLVS-KLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQssyk 2591
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKKAEELKKAEEENKiKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK---- 1709

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2592 nlENELELTKMDKMSFVEKVNKMTAKetELQREMHEMAQKTAELQEElSGEKNRLAgelQLLLEEIKSSKyevEIQTYRE 2671
Cdd:PTZ00121 1710 --KEAEEKKKAEELKKAEEENKIKAE--EAKKEAEEDKKKAEEAKKD-EEEKKKIA---HLKKEEEKKAE---EIRKEKE 1778

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2672 KLTSKEECLSSQKLEIDLLKSSKEELNNSlkattqilEELKKTKMDNLKYVNQlKKENERAQGKmKLLIKSCKQLEEEKE 2751
Cdd:PTZ00121 1779 AVIEEELDEEDEKRRMEVDKKIKDIFDNF--------ANIIEGGKEGNLVIND-SKEMEDSAIK-EVADSKNMQLEEADA 1848

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*....
gi 767908145 2752 ILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADE 2800
Cdd:PTZ00121 1849 FEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDD 1897
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2053-2659 1.29e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2053 ELENQIAQLNKEKELLvKESESLQARLSESDyeklnvskaLEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2132
Cdd:COG1196   197 ELERQLEPLERQAEKA-ERYRELKEELKELE---------AELLLLKLRELEAELEELEAELEELEAELEELEAELAELE 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2133 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEmarslkvfeldlvtLRSEK 2212
Cdd:COG1196   267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE--------------LEEEL 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2213 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPP 2292
Cdd:COG1196   333 EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2293 IEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAK 2372
Cdd:COG1196   413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2373 IEGMTQSLRGLE--LDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQmkEKSSTAMEMLQTQLKEL 2450
Cdd:COG1196   493 LLLLLEAEADYEgfLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVV--EDDEVAAAAIEYLKAAK 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2451 NERVAAL-HNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEisRLKN 2529
Cdd:COG1196   571 AGRATFLpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG--RLRE 648

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2530 QIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVE 2609
Cdd:COG1196   649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|
gi 767908145 2610 KVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKS 2659
Cdd:COG1196   729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 2069-2800 5.69e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 5.69e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2069 VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERE 2148
Cdd:PTZ00121 1066 VGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA 1145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2149 NDSLKDKVENLERELQMSEENQElvILDAENSKAEVETLKTqiEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSE 2228
Cdd:PTZ00121 1146 RKAEDAKRVEIARKAEDARKAEE--ARKAEDAKKAEAARKA--EEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAE 1221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2229 LDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQnqlKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSiEKLRa 2308
Cdd:PTZ00121 1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIR---KFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA-DEAK- 1296

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2309 rlEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDvv 2388
Cdd:PTZ00121 1297 --KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK-- 1372

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2389 tiRSEKENLTNELQKEQERISELEIINSSFENilQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKE 2468
Cdd:PTZ00121 1373 --KEEAKKKADAAKKKAEEKKKADEAKKKAEE--DKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADE 1448

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2469 QNLSSQveclELEKAQLLQGLDEAKNNYIVLQSSVngliqEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEH 2548
Cdd:PTZ00121 1449 AKKKAE----EAKKAEEAKKKAEEAKKADEAKKKA-----EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE 1519

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2549 QLWKEQNLElrnltvELEQKIQVLQSKNASLQDTLEVLQSSyKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHE- 2627
Cdd:PTZ00121 1520 EAKKADEAK------KAEEAKKADEAKKAEEKKKADELKKA-EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEa 1592

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2628 ---MAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKyEVEIQTYREKLTSKEECLSSQKLEidllkssKEELNNSLKAt 2704
Cdd:PTZ00121 1593 rieEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAE-EEKKKVEQLKKKEAEEKKKAEELK-------KAEEENKIKA- 1663

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2705 tqilEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2784
Cdd:PTZ00121 1664 ----AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA 1739

                         730
                  ....*....|....*.
gi 767908145 2785 KELKETLEEKTKEADE 2800
Cdd:PTZ00121 1740 EEDKKKAEEAKKDEEE 1755
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1772-2415 5.97e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 75.10  E-value: 5.97e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1772 LQLRVKETSNENL-RLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLmtkieacIELEKIVGELKKENSDLSEKLEYFS 1850
Cdd:PRK03918  155 LGLDDYENAYKNLgEVIKEIKRRIERLEKFIKRTENIEELIKEKEKEL-------EEVLREINEISSELPELREELEKLE 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1851 CDHQELLQRVETSEGLNSDLEmhadkssredigdNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEaDLEVVQT 1930
Cdd:PRK03918  228 KEVKELEELKEEIEELEKELE-------------SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAE 293

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1931 EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELEshqseclhciqvaeaEVK 2010
Cdd:PRK03918  294 EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLE---------------ELE 358

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2011 EKTELLQtlssDVSELLKDKTHLQEKLQSLEKDsqalsltkcELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVS 2090
Cdd:PRK03918  359 ERHELYE----EAKAKKEELERLKKRLTGLTPE---------KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELK 425

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2091 KALEAALVEKGEFAL--RLSSTQEEVHQLRRGIEKLRvRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEE 2168
Cdd:PRK03918  426 KAIEELKKAKGKCPVcgRELTEEHRKELLEEYTAELK-RIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQ 504

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2169 NQELvildaenskaEVETLKTQIEEMARSLKVFEL---DLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQ 2245
Cdd:PRK03918  505 LKEL----------EEKLKKYNLEELEKKAEEYEKlkeKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAE 574

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2246 AEIQIKEESKTAVEMLQNQLKElneavaalcgdqeimkateqsLDPPIEEEHQLRNSIEKLRARLEADEKKQLcvlqQLK 2325
Cdd:PRK03918  575 LLKELEELGFESVEELEERLKE---------------------LEPFYNEYLELKDAEKELEREEKELKKLEE----ELD 629

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2326 ESEHHADLLKGRVENLERELEiaRTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQ 2405
Cdd:PRK03918  630 KAFEELAETEKRLEELRKELE--ELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707

                         650
                  ....*....|
gi 767908145 2406 ERISELEIIN 2415
Cdd:PRK03918  708 KAKKELEKLE 717
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2208-2804 2.76e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 69.76  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2208 LRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQ 2287
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2288 SLDPPIEEEHQLRNSiEKLRARLEADEKKQLC---------VLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALE 2358
Cdd:pfam15921  342 DKIEELEKQLVLANS-ELTEARTERDQFSQESgnlddqlqkLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2359 AENSKGEVETLKAKIEGMTQSLRG-LELDVVTIRSEKENLtnelQKEQERISELEIINSSFENILQEKEQEKVQMkEKSS 2437
Cdd:pfam15921  421 LDDRNMEVQRLEALLKAMKSECQGqMERQMAAIQGKNESL----EKVSSLTAQLESTKEMLRKVVEELTAKKMTL-ESSE 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2438 TAMEMLQTQLKELNERVaalhndqEACKAKEQNLSSQVECleleKAQLLQGLDEAKNNYIVLQSSVNGLiqevedgKQKL 2517
Cdd:pfam15921  496 RTVSDLTASLQEKERAI-------EATNAEITKLRSRVDL----KLQELQHLKNEGDHLRNVQTECEAL-------KLQM 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2518 EKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQ-NLELRNLTVELeQKIQVLQSKNASLQDTLEVLQSsyknlenE 2596
Cdd:pfam15921  558 AEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQlEKEINDRRLEL-QEFKILKDKKDAKIRELEARVS-------D 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2597 LELTKMdkmsfvekvnKMTAKETELQREMHEMAQKTAELQEELSGEKNrlagELQLLLEEiksskYEVEIQTYREKLTSK 2676
Cdd:pfam15921  630 LELEKV----------KLVNAGSERLRAVKDIKQERDQLLNEVKTSRN----ELNSLSED-----YEVLKRNFRNKSEEM 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2677 EECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKE 2756
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEE 770

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 767908145  2757 LSQLqaAQEKQKTGTVMDTKVDELTTeIKELKETLEEKTKEADEYLDK 2804
Cdd:pfam15921  771 KNKL--SQELSTVATEKNKMAGELEV-LRSQERRLKEKVANMEVALDK 815
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1761-2271 3.54e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.32  E-value: 3.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1761 DFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDR-------KVESLLNEMKELDSKLHLQEVQL------MTKIEACI- 1826
Cdd:PRK03918  183 KFIKRTENIEELIKEKEKELEEVLREINEISSELPelreeleKLEKEVKELEELKEEIEELEKELeslegsKRKLEEKIr 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1827 ELEKIVGELKKENSDLSEKLEyfscDHQELLQRVETSEGLNSDLEMHADKSS---------REDIGDNVAKVND--SWKE 1895
Cdd:PRK03918  263 ELEERIEELKKEIEELEEKVK----ELKELKEKAEEYIKLSEFYEEYLDELReiekrlsrlEEEINGIEERIKEleEKEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1896 RFLDVENELSRIRSEKASIEHEA-LYLEADLEVVQTEKLCLEKDNENKQKvivcLEEELSVVTSERNQLRGELDTMSKKT 1974
Cdd:PRK03918  339 RLEELKKKLKELEKRLEELEERHeLYEEAKAKKEELERLKKRLTGLTPEK----LEKELEELEKAKEEIEEEISKITARI 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1975 TALDQLSEKMKEKTQELESHQSECLHCiqVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKdsqalsltkcEL 2054
Cdd:PRK03918  415 GELKKEIKELKKAIEELKKAKGKCPVC--GRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRK----------EL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2055 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKaLEAALVEKGEFALRLSSTQEEVHQLRRGIEKLrvriEADEKK 2134
Cdd:PRK03918  483 RELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEE-LEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL----EELKKK 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2135 QLHIAEKLKERERENDSLKDKVENL--ERELQMSEENQEL-----VILDAENSKAEVETLKTQIEEMARSLKVFELDLVT 2207
Cdd:PRK03918  558 LAELEKKLDELEEELAELLKELEELgfESVEELEERLKELepfynEYLELKDAEKELEREEKELKKLEEELDKAFEELAE 637

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767908145 2208 LRSEKENLTKQIQEKQGQLSELD---------KLLSSFKSLLEEKEQAEIQIKEESKTAvEMLQNQLKELNEA 2271
Cdd:PRK03918  638 TEKRLEELRKELEELEKKYSEEEyeelreeylELSRELAGLRAELEELEKRREEIKKTL-EKLKEELEEREKA 709
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2300-2824 4.09e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 69.30  E-value: 4.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2300 RNSIEKLRARLEADEKKQLcvLQQLKESEHHADLLKGRVENLERELEIARTNQEHAAL---EAENSKGEVETLKAKIEGM 2376
Cdd:PRK02224  186 RGSLDQLKAQIEEKEEKDL--HERLNGLESELAELDEEIERYEEQREQARETRDEADEvleEHEERREELETLEAEIEDL 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2377 TQSLRGLEldvvtirSEKENLTNELQKEQERISELEiinssfenilqEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAA 2456
Cdd:PRK02224  264 RETIAETE-------REREELAEEVRDLRERLEELE-----------EERDDLLAEAGLDDADAEAVEARREELEDRDEE 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2457 LHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEq 2536
Cdd:PRK02224  326 LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP- 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2537 lvSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQ---SKNASLQ------------------DTLEVLQSSYKNLEN 2595
Cdd:PRK02224  405 --VDLGNAEDFLEELREERDELREREAELEATLRTARervEEAEALLeagkcpecgqpvegsphvETIEEDRERVEELEA 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2596 ELELTKMDKMSFVEKVNKM-TAKETELQREMHEmaqKTAELQEELSGEKNRLAGELQLLLEEIK--SSKYEVEIQTYREK 2672
Cdd:PRK02224  483 ELEDLEEEVEEVEERLERAeDLVEAEDRIERLE---ERREDLEELIAERRETIEEKRERAEELRerAAELEAEAEEKREA 559

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2673 LTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKmdnlKYVNQLKKENERAQGKMKLLIKSCKQLEEEKE- 2751
Cdd:PRK02224  560 AAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIA----DAEDEIERLREKREALAELNDERRERLAEKREr 635

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767908145 2752 --ILQKEL--SQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLET 2824
Cdd:PRK02224  636 krELEAEFdeARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEALEA 712
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2139-2768 6.68e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.55  E-value: 6.68e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2139 AEKLKEREREndsLKDKVENLERELQMSEENQELVildaENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQ 2218
Cdd:PRK03918  164 YKNLGEVIKE---IKRRIERLEKFIKRTENIEELI----KEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2219 IQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIkEESKTAVEMLQNQLKELNEavaaLCGDQEIMKATEQSLDPPIEEEHQ 2298
Cdd:PRK03918  237 KEEIEELEKELESLEGSKRKLEEKIRELEERI-EELKKEIEELEEKVKELKE----LKEKAEEYIKLSEFYEEYLDELRE 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2299 LRNSIEKLRARLEADEKKqlcvLQQLKESEHHADLLKGRVENLERELEIARTNQEhAALEAENSKGEVETLKAKIEGMTq 2378
Cdd:PRK03918  312 IEKRLSRLEEEINGIEER----IKELEEKEERLEELKKKLKELEKRLEELEERHE-LYEEAKAKKEELERLKKRLTGLT- 385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2379 sLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQ--------MKEKSSTAMEMLQTQLKEL 2450
Cdd:PRK03918  386 -PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRI 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2451 NERVAALHNDQEACKAKEQNLSSQVEcLELEKAQLLQGLDEAKNnyivLQSSVNGL-IQEVEDGKQKLEKKDEEISRLKN 2529
Cdd:PRK03918  465 EKELKEIEEKERKLRKELRELEKVLK-KESELIKLKELAEQLKE----LEEKLKKYnLEELEKKAEEYEKLKEKLIKLKG 539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2530 QIQDQEQLVSKLSqvegehqlwkeqnlELRNLTVELEQKIQVLQSKNASLQDTLEVLQ-SSYKNLENELELTKmdkmSFV 2608
Cdd:PRK03918  540 EIKSLKKELEKLE--------------ELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELE----PFY 601

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2609 EKVNKMTAKETELQREMHEMAQKTAELQ---EELSGEKNRLAgELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKL 2685
Cdd:PRK03918  602 NEYLELKDAEKELEREEKELKKLEEELDkafEELAETEKRLE-ELRKELEELEKKYSEEEYEELREEYLELSRELAGLRA 680

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2686 EIDLLKSSKEELNNSLKATTQILEELKKTKmdnlkyvnqlkkeneraqgkmklliksckqleEEKEILQKELSQLQAAQE 2765
Cdd:PRK03918  681 ELEELEKRREEIKKTLEKLKEELEEREKAK--------------------------------KELEKLEKALERVEELRE 728


                  ...
gi 767908145 2766 KQK 2768
Cdd:PRK03918  729 KVK 731
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2300-2823 6.79e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.55  E-value: 6.79e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2300 RNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEhaalEAENSKGEVETLKAKIEGMTQS 2379
Cdd:PRK03918  178 IERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK----ELEELKEEIEELEKELESLEGS 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2380 LRGLELDVVTIRSEKENLTNELQKEQERISELE---------IINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKEL 2450
Cdd:PRK03918  254 KRKLEEKIRELEERIEELKKEIEELEEKVKELKelkekaeeyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL 333

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2451 NERVAALhndqEACKAKEQNLSSQVECLElEKAQLLQGLDEAKNNYIVLQSSVNGL--------IQEVEDGKQKLEKK-- 2520
Cdd:PRK03918  334 EEKEERL----EELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLtpeklekeLEELEKAKEEIEEEis 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2521 --DEEISRLKNQIQDQEQLVSKLSQVEGE-----HQLWKEQNLEL-RNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKN 2592
Cdd:PRK03918  409 kiTARIGELKKEIKELKKAIEELKKAKGKcpvcgRELTEEHRKELlEEYTAELKRIEKELKEIEEKERKLRKELRELEKV 488

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2593 LENELELTKMDKMsfvekVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSK-YEVEIQTYRE 2671
Cdd:PRK03918  489 LKKESELIKLKEL-----AEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEeLKKKLAELEK 563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2672 KLTSKEECLSSQKLEIDLL--KSSKE----------------ELNNSLKATTQILEELKKTKM---DNLKYVNQLKKENE 2730
Cdd:PRK03918  564 KLDELEEELAELLKELEELgfESVEEleerlkelepfyneylELKDAEKELEREEKELKKLEEeldKAFEELAETEKRLE 643

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2731 RAQGKMKLLIKSCKQLE-EEKEILQKELSQLQAAQEKQKTGtvMDTKVDELTTEIKELKETLEEKTKEADEYldkycsll 2809
Cdd:PRK03918  644 ELRKELEELEKKYSEEEyEELREEYLELSRELAGLRAELEE--LEKRREEIKKTLEKLKEELEEREKAKKEL-------- 713

                         570
                  ....*....|....
gi 767908145 2810 ishEKLEKAKEMLE 2823
Cdd:PRK03918  714 ---EKLEKALERVE 724
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2300-2666 7.65e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 7.65e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2300 RNSIEKLRARLEADEKKQLcVLQQLKESEHHADLLKGRVENLERELEIARTNQEHA----ALEAENSKGEVETLKAKIEG 2375
Cdd:TIGR02169  156 RKIIDEIAGVAEFDRKKEK-ALEELEEVEENIERLDLIIDEKRQQLERLRREREKAeryqALLKEKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2376 MTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiinssfenilQEKEQEKVQMKEKSSTAMEMLQTQLKELnerva 2455
Cdd:TIGR02169  235 LERQKEAIERQLASLEEELEKLTEEISELEKRLEEIE----------QLLEELNKKIKDLGEEEQLRVKEKIGEL----- 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2456 alHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEaknnyivLQSSVNGLIQEVEDGKQKLEKKDEEISRLKnqiQDQE 2535
Cdd:TIGR02169  300 --EAEIASLERSIAEKERELEDAEERLAKLEAEIDK-------LLAEIEELEREIEEERKRRDKLTEEYAELK---EELE 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2536 QLVSKLSQVEGEHQLWKEQnlelrnlTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMT 2615
Cdd:TIGR02169  368 DLRAELEEVDKEFAETRDE-------LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELE 440

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 767908145  2616 AKETELQREMHEMAQKTAELQEELSGEKN---RLAGELQLLLEEIKSSKYEVEI 2666
Cdd:TIGR02169  441 EEKEDKALEIKKQEWKLEQLAADLSKYEQelyDLKEEYDRVEKELSKLQRELAE 494
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1921-2369 1.44e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 67.37  E-value: 1.44e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1921 LEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLH 2000
Cdd:PRK02224  256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2001 CIQVAEAEVKEKTELLQTLSSDVSELlkdkthlQEKLQSLEKDSQALSLTKCELENQIAQLNKE---------------- 2064
Cdd:PRK02224  336 AAQAHNEEAESLREDADDLEERAEEL-------REEAAELESELEEAREAVEDRREEIEELEEEieelrerfgdapvdlg 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2065 -----KELLVKESESLQARLSESDYEKLNVSKALEAAL--------------VEKGEFALRLSSTQEEVHQLRRGIEKLR 2125
Cdd:PRK02224  409 naedfLEELREERDELREREAELEATLRTARERVEEAEalleagkcpecgqpVEGSPHVETIEEDRERVEELEAELEDLE 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2126 VRIEADEKKqLHIAEKLKERERENDSLKDKVENL------------ERELQMSEENQELVILD--AENSKAEVETLKTQI 2191
Cdd:PRK02224  489 EEVEEVEER-LERAEDLVEAEDRIERLEERREDLeeliaerretieEKRERAEELRERAAELEaeAEEKREAAAEAEEEA 567

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2192 EEMARSLKVFELDLVTLRSEKENLTKqIQEKQGQLSELDKLLSSfkslLEEKEQAEIQIKEESKTAVEMLQNQLKELNEA 2271
Cdd:PRK02224  568 EEAREEVAELNSKLAELKERIESLER-IRTLLAAIADAEDEIER----LREKREALAELNDERRERLAEKRERKRELEAE 642

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2272 V--AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKqlcvLQQLKESEHHADLLKGRVENLERELEIAR 2349
Cdd:PRK02224  643 FdeARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENE----LEELEELRERREALENRVEALEALYDEAE 718

                         490       500
                  ....*....|....*....|.
gi 767908145 2350 TNQE-HAALEAENSKGEVETL 2369
Cdd:PRK02224  719 ELESmYGDLRAELRQRNVETL 739
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 433-1187 3.06e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 3.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   433 NVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNI 512
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   513 KQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVAdlEKQRDCSQDLLKKREHHIEQLNDKLSKTE 592
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL--EAELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   593 KEsKALLSALElkkkeyeelkeektlfscwkSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEynERVRTLEMDR 672
Cdd:TIGR02168  393 LQ-IASLNNEI--------------------ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQ--AELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   673 ENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKhQKEIENMCLKTSQLTGQVEDLEHKLQLLSNeimDKDRC 752
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKALLKNQSGLSG---ILGVL 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   753 YQDLH--AEYES--LRDLLKSKDASLVTNEDHQRSLLAFDQQPAMhhSFANIIGEQGSMPSERSECRLEADQSPKNSAIL 828
Cdd:TIGR02168  526 SELISvdEGYEAaiEAALGGRLQAVVVENLNAAKKAIAFLKQNEL--GRVTFLPLDSIKGTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   829 QNRVDslEFSLESQKQMNSDLQkqceeLVQIKGEIEE--NLMKAEQMHQSFVAETSQRISKLQEDTSAHqnvvAETLSAL 906
Cdd:TIGR02168  604 AKDLV--KFDPKLRKALSYLLG-----GVLVVDDLDNalELAKKLRPGYRIVTLDGDLVRPGGVITGGS----AKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   907 ENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASL 986
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   987 NQEKMNLIQKSESFANYIDEREKSISELS----------DQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECL 1056
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEaeieeleaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1057 LNECTSLCENRKNELEQLKEAFAK------EHQEFLTKLAFAEERNQNLMLELETVQQALRSEM---TDNQNNSKSEAGG 1127
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESlaaeieELEELIEELESELEALLNERASLEEALALLRSELeelSEELRELESKRSE 912

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767908145  1128 LKQEIMTLKEEQNKMQKEVNDLLQENEQL-----------MKVMKTKHECQNLESEPIRNSVKERESERNQ 1187
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLqerlseeysltLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 22-746 4.18e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 4.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    22 ELEGQLDKLKKEKQQRQ------FQLDSLEAALQKQKQKVENEKTEGTN--LKRENQRLMEICESLEKTKQKIS---HEL 90
Cdd:TIGR02168  197 ELERQLKSLERQAEKAErykelkAELRELELALLVLRLEELREELEELQeeLKEAEEELEELTAELQELEEKLEelrLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    91 QVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYysgsKYEDLKEK 170
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE----KLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   171 YNKEVEERKRLEAEVKALQAKKASQTlPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQ 250
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEELE-EQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   251 EVTPSRSTLQIGKRDANSSFFDNSssphlLDQLKAQNQELRNKINELELRLQGHEKEM---KGQVNKFQELQLQLE---K 324
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEE-----LERLEEALEELREELEEAEQALDAAERELaqlQARLDSLERLQENLEgfsE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   325 AKVELIEKEKVLNKCRD---ELVRTTAQYDQAstKYTALEQKLKKL-TEDLSCQRQNAES---------ARCSLEQKIKE 391
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGvlsELISVDEGYEAA--IEAALGGRLQAVvVENLNAAKKAIAFlkqnelgrvTFLPLDSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   392 KEKEFQEELSRQQRSFQTLDQECIQMKARL-------------TQELQQAKNMHNVLQAEL------------------- 439
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvVDDLDNALELAKKLRPGYrivtldgdlvrpggvitgg 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   440 -DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQ 518
Cdd:TIGR02168  665 sAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   519 SQNFAEEMKAKNTSQETMLRDLQEKINqqENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLE--EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   599 LSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVE 678
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   679 IRNLHNVLDSK------------SVEVETQKLAYMELQQKAEFSDQkHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI 746
Cdd:TIGR02168  903 LRELESKRSELrreleelreklaQLELRLEGLEVRIDNLQERLSEE-YSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 283-1020 1.04e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 1.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   283 LKAQNQELRNKINELE---LRLQGHEKEMKGQVNKfqeLQLQLEKAKvELIEKEKVLNKCRDELvrTTAQYDQASTKYTA 359
Cdd:TIGR02168  170 YKERRKETERKLERTRenlDRLEDILNELERQLKS---LERQAEKAE-RYKELKAELRELELAL--LVLRLEELREELEE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   360 LEQKLKKLTEDLscqrqNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439
Cdd:TIGR02168  244 LQEELKEAEEEL-----EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQS 519
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   520 QNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALL 599
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   600 SALELKKKEYEELKEEKTLFscwksENEKLLTQMESEKENLQSKINHLETCLKtQQIKSHEYNER--VRTLEMDRENLSV 677
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQ-----ENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAaiEAALGGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   678 EIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLH 757
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   758 AEYESLRDLlkSKDASLVTNEDH----------------------QRSLLAFDQQPAMHHSFANII--------GEQGSM 807
Cdd:TIGR02168  633 NALELAKKL--RPGYRIVTLDGDlvrpggvitggsaktnssilerRREIEELEEKIEELEEKIAELekalaelrKELEEL 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   808 PSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMhqsfVAETSQRISK 887
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE----LAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   888 LQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKR 967
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 767908145   968 EIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQ 1020
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 288-568 1.04e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  288 QELRNKINELELRLQGH-----EKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Cdd:COG1196   216 RELKEELKELEAELLLLklrelEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  363 KLKKLTEDLSCQRQNAESARcsleqKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKL 442
Cdd:COG1196   296 ELARLEQDIARLEERRRELE-----ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  443 TSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNF 522
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 767908145  523 AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRD 568
Cdd:COG1196   451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2389-2823 2.98e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.16  E-value: 2.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2389 TIRSEKENLTNELQKE---QERISELEiinSSFENILQE---------KEQEKVQMKEKSSTAMEMLQTQLKELNERVAA 2456
Cdd:PRK03918  173 EIKRRIERLEKFIKRTeniEELIKEKE---KELEEVLREineisselpELREELEKLEKEVKELEELKEEIEELEKELES 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2457 LHNDQEACKAKEQNLSSQVECLEL------EKAQLLQGLDEAKNNYIVLqssvNGLIQEVEDGKQKLEKkdeEISRLKNQ 2530
Cdd:PRK03918  250 LEGSKRKLEEKIRELEERIEELKKeieeleEKVKELKELKEKAEEYIKL----SEFYEEYLDELREIEK---RLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2531 IQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQsKNASLQDTLEVLQSSYKN-----LENELELTKMDKM 2605
Cdd:PRK03918  323 INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYE-EAKAKKEELERLKKRLTGltpekLEKELEELEKAKE 401

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2606 SFVEKVNKMTAKETELQREMHEMAQKTaelqEELSGEKNRLAGELQLLLEEIKS---SKYEVEIQTYRE---KLTSKEEC 2679
Cdd:PRK03918  402 EIEEEISKITARIGELKKEIKELKKAI----EELKKAKGKCPVCGRELTEEHRKellEEYTAELKRIEKelkEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2680 LSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQ 2759
Cdd:PRK03918  478 LRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKK 557

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767908145 2760 LQAAQEKQKTgtvMDTKVDELTTEIKELK----ETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2823
Cdd:PRK03918  558 LAELEKKLDE---LEEELAELLKELEELGfesvEELEERLKELEPFYNEYLELKDAEKELEREEKELK 622
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1791-2536 3.68e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 62.83  E-value: 3.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1791 EDRDRKVESLLNEMKELDSKLH----LQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVEtsegl 1866
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNesneLHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQ----- 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1867 NSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEkasiehealyleadleVVQTEKLCLEKDNENKQKVI 1946
Cdd:pfam15921  149 NTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSI----------------LVDFEEASGKKIYEHDSMST 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1947 VCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQE-----LESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Cdd:pfam15921  213 MHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARS 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2022 DVSELLKDKTHLQEklQSLEKDSQALSLTKcELENQIAQLNKEkelLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Cdd:pfam15921  293 QANSIQSQLEIIQE--QARNQNSMYMRQLS-DLESTVSQLRSE---LREAKRMYEDKIEELEKQLVLANSELTEARTERD 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2102 EFALRLSSTQEEVHQLRRGIEKLR--VRIEADEKKQL------------HIAEKLKERERENDSLKDKVENLERELQMSE 2167
Cdd:pfam15921  367 QFSQESGNLDDQLQKLLADLHKREkeLSLEKEQNKRLwdrdtgnsitidHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2168 ENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN-------LTKQIQEKQGQLSELDKLLSSFKSLL 2240
Cdd:pfam15921  447 ERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESsertvsdLTASLQEKERAIEATNAEITKLRSRV 526

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2241 EEKEQAEIQIKEES------KTAVEMLQNQLKELNEAVaalcgdqEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADE 2314
Cdd:pfam15921  527 DLKLQELQHLKNEGdhlrnvQTECEALKLQMAEKDKVI-------EILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEI 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2315 KKQLCVLQQLKESEHHADL----LKGRVENLERE---LEIARTNQEHAALEAENSK----GEVETLKAKIEGMTQSLRGL 2383
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAkireLEARVSDLELEkvkLVNAGSERLRAVKDIKQERdqllNEVKTSRNELNSLSEDYEVL 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2384 ELDVVTIRSEKENLTNELQKE-QERISELEIINSSFENIL-QEKEQEKVQM-KEKSSTA----MEMLQTQLKELNERVAA 2456
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKMQlKSAQSELEQTRNTLKSMEgSDGHAMKVAMgMQKQITAkrgqIDALQSKIQFLEEAMTN 759

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2457 LHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDeaknnyiVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQ 2536
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELE-------VLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQ 832
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 280-598 4.20e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 4.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   280 LDQLKAQNQELRNKINELELRLQGHEKEmKGQVNKFQELQLQLEKAKVELIEKEKvlNKCRDELVRTTAQYDqastkytA 359
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEK--EALERQKEAIERQLA-------S 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLT---QELQQAKNMHNVLQ 436
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAekeRELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCL 516
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   517 NQSQNFAEEMKAKNTSQETMLRDLQEKINQQENslTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESK 596
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEE--EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486


                   ..
gi 767908145   597 AL 598
Cdd:TIGR02169  487 KL 488
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2392-2843 4.80e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.35  E-value: 4.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2392 SEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSsTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2471
Cdd:TIGR04523  152 KELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL-LKLELLLSNLKKKIQKNKSLESQISELKKQNNQL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2472 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ-------- 2543
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNqkeqdwnk 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2544 -VEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNL-------ENELELTKMDKMSFVEKVNKMT 2615
Cdd:TIGR04523  311 eLKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKqreleekQNEIEKLKKENQSYKQEIKNLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2616 AKETELQREMHEMAQKTAELQEELSG---EKNRLAGELQLLLEEIksSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKS 2692
Cdd:TIGR04523  391 SQINDLESKIQNQEKLNQQKDEQIKKlqqEKELLEKEIERLKETI--IKNNSEIKDLTNQDSVKELIIKNLDNTRESLET 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2693 SKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSqlqaaqEKQKTGTV 2772
Cdd:TIGR04523  469 QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKK------EKESKISD 542

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767908145  2773 MDTKVDELTTEIK--ELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2843
Cdd:TIGR04523  543 LEDELNKDDFELKkeNLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL 615
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2129-2820 9.20e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.53  E-value: 9.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2129 EADEKKQLHIAEKLKERERENdslKDKVENLERElqmsEENQELVILDAENSKAEVETLKTQIEEMARSLKVfeLDLVTL 2208
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETEN---LAELIIDLEE----LKLQELKLKEQAKKALEYYQLKEKLELEEEYLLY--LDYLKL 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2209 RSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVaalcgdQEIMKATEQS 2288
Cdd:pfam02463  235 NEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEEL------KSELLKLERR 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2289 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAensKGEVET 2368
Cdd:pfam02463  309 KVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK---KLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2369 LKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLK 2448
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2449 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLK 2528
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2529 NQIQDQEQLVSKLSQVEGEHqlwKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKmSFV 2608
Cdd:pfam02463  546 STAVIVEVSATADEVEERQK---LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADED-DKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2609 EKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAG-ELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEI 2687
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKsEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2688 DLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQ 2767
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 767908145  2768 KTGTvmDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKE 2820
Cdd:pfam02463  782 KTEK--LKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKE 832
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2212-2697 1.05e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.94  E-value: 1.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2212 KENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEesktavemLQNQLKELNEAVAALcgdqeimkATEQSLDP 2291
Cdd:COG4717    66 PELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEE--------LEAELEELREELEKL--------EKLLQLLP 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2292 PIEEEHQLRNSIEKLRARLEADEKKqlcvLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEA-ENSKGEVETLK 2370
Cdd:COG4717   130 LYQELEALEAELAELPERLEELEER----LEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQ 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2371 AKIEGMTQSLRGLELDVVTIRSEKENLTNEL--QKEQERISELEIINSSFeNILQEKEQEKVQMKEKSSTAMEMLQTQLK 2448
Cdd:COG4717   206 QRLAELEEELEEAQEELEELEEELEQLENELeaAALEERLKEARLLLLIA-AALLALLGLGGSLLSLILTIAGVLFLVLG 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2449 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLK 2528
Cdd:COG4717   285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2529 -NQIQDQEQLVSKLSQVEGEHQLWK--EQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQssYKNLENELEltkmdkm 2605
Cdd:COG4717   365 lEELEQEIAALLAEAGVEDEEELRAalEQAEEYQELKEELEELEEQLEELLGELEELLEALD--EEELEEELE------- 435

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2606 sfvekvnkmtaketELQREMHEMAQKTAELQEELSgeknRLAGELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKL 2685
Cdd:COG4717   436 --------------ELEEELEELEEELEELREELA----ELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKL 497

                         490
                  ....*....|..
gi 767908145 2686 EIDLLKSSKEEL 2697
Cdd:COG4717   498 ALELLEEAREEY 509
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2106-2598 1.30e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.08  E-value: 1.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2106 RLSSTQEEVHQLRRGIEKL-----------RVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVI 2174
Cdd:COG4913   236 DLERAHEALEDAREQIELLepirelaeryaAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2175 LDAENSKAEVETLKTQIeemaRSLKVFELDlvTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEES 2254
Cdd:COG4913   316 ARLDALREELDELEAQI----RGNGGDRLE--QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2255 KTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSI----EKLRARLEA------DEKKQLCVLQQL 2324
Cdd:COG4913   390 AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparlLALRDALAEalgldeAELPFVGELIEV 469

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2325 KESE-----------------------HHADL--------LKGRVeNLEReleiARTNQEHAALEAENSKGEVETLKAKI 2373
Cdd:COG4913   470 RPEEerwrgaiervlggfaltllvppeHYAAAlrwvnrlhLRGRL-VYER----VRTGLPDPERPRLDPDSLAGKLDFKP 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2374 EGMTQSLRGL---ELDVVTIRSEKE------NLTNELQ----------KEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:COG4913   545 HPFRAWLEAElgrRFDYVCVDSPEElrrhprAITRAGQvkgngtrhekDDRRRIRSRYVLGFDNRAKLAALEAELAELEE 624

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2435 ksstAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKA-----QLLQGLDEAKNNYIVLQSSVNGLIQE 2509
Cdd:COG4913   625 ----ELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaeleAELERLDASSDDLAALEEQLEELEAE 700

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2510 VEDGKQKLEKKDEEISRLKNQIQD----QEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQsknASLQDTLEV 2585
Cdd:COG4913   701 LEELEEELDELKGEIGRLEKELEQaeeeLDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELR---ENLEERIDA 777

                         570
                  ....*....|...
gi 767908145 2586 LQSSYKNLENELE 2598
Cdd:COG4913   778 LRARLNRAEEELE 790
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2424-2814 2.41e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.08  E-value: 2.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2424 EKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALhndqEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSV 2503
Cdd:PRK03918  148 EKVVRQILGLDDYENAYKNLGEVIKEIKRRIERL----EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREEL 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2504 NGLIQEVEdgkqKLEKKDEEISRLKNQIQDQEQLVSKLsqvegehqlwKEQNLELRNLTVELEQKIQVLQSKNASLQDtL 2583
Cdd:PRK03918  224 EKLEKEVK----ELEELKEEIEELEKELESLEGSKRKL----------EEKIRELEERIEELKKEIEELEEKVKELKE-L 288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2584 EVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELqEELSGEKNRLAGELQLLLEEIKSSKYE 2663
Cdd:PRK03918  289 KEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-EELKKKLKELEKRLEELEERHELYEEA 367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2664 VEIQTYREKLTSKEECLSSQKL--EIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKK-------------E 2728
Cdd:PRK03918  368 KAKKEELERLKKRLTGLTPEKLekELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgreltE 447

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2729 NERAQ------GKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYL 2802
Cdd:PRK03918  448 EHRKElleeytAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEY 527

                         410
                  ....*....|..
gi 767908145 2803 DKYCSLLISHEK 2814
Cdd:PRK03918  528 EKLKEKLIKLKG 539
PRK11281 PRK11281
mechanosensitive channel MscK;
2140-2584 2.49e-08

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 59.93  E-value: 2.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2140 EKLKERERENDSLKDKVENLERELQmsEENQELVILDAENSKAEVETLKTqieemarslkvfeLDLVTLRSEKENLTKQI 2219
Cdd:PRK11281   73 DKIDRQKEETEQLKQQLAQAPAKLR--QAQAELEALKDDNDEETRETLST-------------LSLRQLESRLAQTLDQL 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2220 QEKQGQLSELDKLLSSFKSLLeEKEQAEIQikeESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLdppieeehqL 2299
Cdd:PRK11281  138 QNAQNDLAEYNSQLVSLQTQP-ERAQAALY---ANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQAL---------L 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2300 RNSIEKLRARLEADEkkqlcVLQQLKESEHhaDLLKGRVENLERELEIART--NQEHAALeAENSKGEVETLKAKIEGMT 2377
Cdd:PRK11281  205 NAQNDLQRKSLEGNT-----QLQDLLQKQR--DYLTARIQRLEHQLQLLQEaiNSKRLTL-SEKTVQEAQSQDEAARIQA 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2378 QSLRGLELDVVTirsekeNLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSStameMLQTQL---KELNERV 2454
Cdd:PRK11281  277 NPLVAQELEINL------QLSQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQIS----VLKGSLllsRILYQQQ 346

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2455 AALHNDQEackakEQNLSSQVECLELEKAQLLQGLDEAknnyivlqSSVNGLIQEVEDGkQKLEKKDEEISRLKNQIQDQ 2534
Cdd:PRK11281  347 QALPSADL-----IEGLADRIADLRLEQFEINQQRDAL--------FQPDAYIDKLEAG-HKSEVTDEVRDALLQLLDER 412

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 767908145 2535 EQLVSKLSqvegehqlwKEQNLELrNLTVELEQKIQVLQSKNASLQDTLE 2584
Cdd:PRK11281  413 RELLDQLN---------KQLNNQL-NLAINLQLNQQQLLSVSDSLQSTLT 452
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 4-720 2.58e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 2.58e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145     4 ALEEWKEGLptrALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTK 83
Cdd:TIGR02168  221 ELRELELAL---LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    84 QKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTtpltpsqyysgSK 163
Cdd:TIGR02168  298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE-----------AE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   164 YEDLKEKYNKEVEERKRLEAEVKALQAKKASQtlpqatMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSA 243
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQIASL------NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   244 SYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQElQLQLE 323
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN-QSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   324 KAK---VELIEKEKVLNKCRDELVRTTAQY-----------------DQASTKYTALEQKLKKLTEDLSCQRQNAESARC 383
Cdd:TIGR02168  520 GILgvlSELISVDEGYEAAIEAALGGRLQAvvvenlnaakkaiaflkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   384 SLEQKIKEKEKEFQ------------------------EELSRQQRSFQTLDQECIQMKARLTQE--------LQQAKNM 431
Cdd:TIGR02168  600 FLGVAKDLVKFDPKlrkalsyllggvlvvddldnalelAKKLRPGYRIVTLDGDLVRPGGVITGGsaktnssiLERRREI 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   432 HNvLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKN 511
Cdd:TIGR02168  680 EE-LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   512 IKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEK------------LKLAVADLEKQRDCSQDLLKKREH 579
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRealdelraeltlLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   580 HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSH 659
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE 918

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767908145   660 EYNERVRTLEMDRENLSVEIRNLhnvLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIEN 720
Cdd:TIGR02168  919 ELREKLAQLELRLEGLEVRIDNL---QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1945-2817 2.74e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 60.06  E-value: 2.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1945 VIVCLEEELSVVTSERNQLRGELD---TMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAE--AEVKEKTELLQTL 2019
Cdd:TIGR00606  153 VIFCHQEDSNWPLSEGKALKQKFDeifSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEkaCEIRDQITSKEAQ 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2020 SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSE----SDYEKLNVSKALEA 2095
Cdd:TIGR00606  233 LESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQLNDLYHNHQR 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2096 ALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSL------KDKVENLERELQMSEEN 2169
Cdd:TIGR00606  313 TVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLiqslatRLELDGFERGPFSERQI 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2170 QELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQ 2249
Cdd:TIGR00606  393 KNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDR 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2250 IKEESKTAVEMLQN-QLKELNEAVAALCGDQEIMKATEQSLDPPI----EEEHQLRNSIEKLRARLEADEKKQLCVLQQL 2324
Cdd:TIGR00606  473 ILELDQELRKAERElSKAEKNSLTETLKKEVKSLQNEKADLDRKLrkldQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIR 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2325 KESEHHADLLKGRVENLERELEIARTnqehaaleAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKE 2404
Cdd:TIGR00606  553 KIKSRHSDELTSLLGYFPNKKQLEDW--------LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2405 QERISEL---EIINSSFENILQEKEQEKVQ--MKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLE 2479
Cdd:TIGR00606  625 EDKLFDVcgsQDEESDLERLKEEIEKSSKQraMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKL 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2480 L-------EKAQLLQGLDEAKNNYIVL----QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEH 2548
Cdd:TIGR00606  705 RlapdklkSTESELKKKEKRRDEMLGLapgrQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESA 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2549 Q-------LWKEQNLELRNLTVELEQKIQVLQSKNASLQDT-----LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTA 2616
Cdd:TIGR00606  785 KvcltdvtIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQqvnqeKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKS 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2617 KETELQREMHEMAQKTAELQeELSGEKNRLAGELQLLLEEIKSSKYEVE-IQTYREKLTSKEECLSSQKLEIDllKSSKE 2695
Cdd:TIGR00606  865 KTNELKSEKLQIGTNLQRRQ-QFEEQLVELSTEVQSLIREIKDAKEQDSpLETFLEKDQQEKEELISSKETSN--KKAQD 941

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2696 ELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDT 2775
Cdd:TIGR00606  942 KVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNL 1021

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 767908145  2776 KVDELTTEIKELKETLEEKTKEADEylDKYCSLLISHEKLEK 2817
Cdd:TIGR00606 1022 TLRKRENELKEVEEELKQHLKEMGQ--MQVLQMKQEHQKLEE 1061
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 280-514 3.03e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.95  E-value: 3.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Cdd:COG1196   262 LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQEciqmkARLTQELQQAKNMHNVLQAEL 439
Cdd:COG1196   342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA-----AELAAQLEELEEAEEALLERL 416

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767908145  440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQ 514
Cdd:COG1196   417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2422-2829 3.10e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 3.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2422 LQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHndQEACKAKE-QNLSSQVEclELEKAQLLQGLDEAKNNYIVLQ 2500
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE--RQAEKAERyKELKAELR--ELELALLVLRLEELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2501 SSVNGLIQEVEDGKQKLEKKDEEIsrlknqiqdqEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQ 2580
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKL----------EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2581 DTLEVLQSSYKNLENELEltkmdkmsfvekvnkmtaketELQREMHEMAQKTAELQEELSGEKNRLAgELQLLLEEIKS- 2659
Cdd:TIGR02168  316 RQLEELEAQLEELESKLD---------------------ELAEELAELEEKLEELKEELESLEAELE-ELEAELEELESr 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2660 -SKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKtkmdnlkyvnqlkkenERAQGKMKL 2738
Cdd:TIGR02168  374 lEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK----------------KLEEAELKE 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2739 LIKSCKQLEEEKEILQKELSQLQAAqekqktgtvmdtkvdeltteikelketLEEKTKEADEYLDKYCSLLISHEKLEKA 2818
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEA---------------------------LEELREELEEAEQALDAAERELAQLQAR 490

                          410
                   ....*....|.
gi 767908145  2819 KEMLETQVAHL 2829
Cdd:TIGR02168  491 LDSLERLQENL 501
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1949-2402 3.44e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 59.75  E-value: 3.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKM------KEKTQELESHQSECLHCIQVAEA--------------- 2007
Cdd:pfam15921  347 LEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLladlhkREKELSLEKEQNKRLWDRDTGNSitidhlrrelddrnm 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2008 EVKEKTELLQTLSSDVS-ELLKDKTHLQEKLQSLEKDSqalSLTkcelenqiAQLNKEKELLVKESESLQARL-----SE 2081
Cdd:pfam15921  427 EVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVS---SLT--------AQLESTKEMLRKVVEELTAKKmtlesSE 495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2082 SDYEKLNVS-----KALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERErendSLKDKV 2156
Cdd:pfam15921  496 RTVSDLTASlqekeRAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIE----ILRQQI 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2157 ENLER----------ELQMSEENQELVILDAENSKAEVETLKT-------QIEEMARSLKVFELDLVTLRSEKENLTKQI 2219
Cdd:pfam15921  572 ENMTQlvgqhgrtagAMQVEKAQLEKEINDRRLELQEFKILKDkkdakirELEARVSDLELEKVKLVNAGSERLRAVKDI 651

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2220 QEKQGQL-SELDKLLSSFKSLLEEKEQAEIQIKEESKtAVEMLQNQLK-ELNEAVAALCGDQEIMKATEQSLDPPIEEEH 2297
Cdd:pfam15921  652 KQERDQLlNEVKTSRNELNSLSEDYEVLKRNFRNKSE-EMETTTNKLKmQLKSAQSELEQTRNTLKSMEGSDGHAMKVAM 730

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2298 QLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGM- 2376
Cdd:pfam15921  731 GMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMe 810

                          490       500       510
                   ....*....|....*....|....*....|
gi 767908145  2377 ----TQSLRGLELDVVTIRSEKENLTNELQ 2402
Cdd:pfam15921  811 valdKASLQFAECQDIIQRQEQESVRLKLQ 840
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1853-2360 3.61e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 3.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1853 HQELL---QRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWK--ERFLDVENELSRIRSEKASIEHEALYLEADLEV 1927
Cdd:COG4913   241 HEALEdarEQIELLEPIRELAERYAAARERLAELEYLRAALRLWFaqRRLELLEAELEELRAELARLEAELERLEARLDA 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1928 VQTEKLCLEKD-NENKQKVIVCLEEELSVVTSERNQLRGELDTMSKkttALDQLSEKMKEKTQELESHQSECLHCIQVAE 2006
Cdd:COG4913   321 LREELDELEAQiRGNGGDRLEQLEREIERLERELEERERRRARLEA---LLAALGLPLPASAEEFAALRAEAAALLEALE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2007 AEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEkdSQALSLTKcELENQIAQLnkEKELLVKES------ESLQARLS 2080
Cdd:COG4913   398 EELEALEEALAEAEAALRDLRRELRELEAEIASLE--RRKSNIPA-RLLALRDAL--AEALGLDEAelpfvgELIEVRPE 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2081 ESDYEKlnvskALEAALvekGEFALRLSSTQE---------EVHQLRRGI--EKLRVRIEADEKKQLH---IAEKLKERE 2146
Cdd:COG4913   473 EERWRG-----AIERVL---GGFALTLLVPPEhyaaalrwvNRLHLRGRLvyERVRTGLPDPERPRLDpdsLAGKLDFKP 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2147 RE-----NDSLKD-----KVENLE----------RELQMS------------EENQELVIldAENSKAEVETLKTQIEEM 2194
Cdd:COG4913   545 HPfrawlEAELGRrfdyvCVDSPEelrrhpraitRAGQVKgngtrhekddrrRIRSRYVL--GFDNRAKLAALEAELAEL 622

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2195 ARSLKVFELDLVTLRSEKENLTKQIQEKQgQLSELDKLLSSFKSLLEEKEQAEIQIK--EESKTAVEMLQNQLKELNEAV 2272
Cdd:COG4913   623 EEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDVASAEREIAELEAELErlDASSDDLAALEEQLEELEAEL 701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2273 AALCGDQEIMKATEQSLDppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL--EIART 2350
Cdd:COG4913   702 EELEEELDELKGEIGRLE---KELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLeeRIDAL 778

                         570
                  ....*....|
gi 767908145 2351 NQEHAALEAE 2360
Cdd:COG4913   779 RARLNRAEEE 788
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1960-2430 3.95e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 59.01  E-value: 3.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1960 RNQLRGELDTMSKKTTALDQL-SEKMKEKTQELESHQSEclhciqvaEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQ 2038
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELnLKELKELEEELKEAEEK--------EEEYAELQEELEELEEELEELEAELEELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2039 SLEKDSQALSLTK--CELENQIAQLNKEKELL---VKESESLQARLSESDYEKLNVSKALEAALVEKGEfalrlsSTQEE 2113
Cdd:COG4717   120 KLEKLLQLLPLYQelEALEAELAELPERLEELeerLEELRELEEELEELEAELAELQEELEELLEQLSL------ATEEE 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDA----ENSKAEVETLKT 2189
Cdd:COG4717   194 LQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAAllalLGLGGSLLSLIL 273

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2190 QIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKL----LSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQL 2265
Cdd:COG4717   274 TIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELeeeeLEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2266 KELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQ-QLKESEHHADLLKGRVENLERE 2344
Cdd:COG4717   354 REAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQlEELLGELEELLEALDEEELEEE 433

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2345 LEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRgleldVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE 2424
Cdd:COG4717   434 LEELEEELEELEEELEELREELAELEAELEQLEEDGE-----LAELLQELEELKAELRELAEEWAALKLALELLEEAREE 508


                  ....*.
gi 767908145 2425 KEQEKV 2430
Cdd:COG4717   509 YREERL 514
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1918-2252 4.41e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 4.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1918 ALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSE 1997
Cdd:TIGR02169  669 SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1998 CLHCIQVAEAEVKEKTELLQTLSSDVSEL------LKDK------THLQEKLQSLEKDSQALSLTKCELENQIAQLNKEK 2065
Cdd:TIGR02169  749 LEQEIENVKSELKELEARIEELEEDLHKLeealndLEARlshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2066 ELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQL-------RRGIEKLRVRIEADEKKQLHI 2138
Cdd:TIGR02169  829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLesrlgdlKKERDELEAQLRELERKIEEL 908

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2139 AEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSkAEVETLKTQIEEMARSLKVFEldLVTLRSEKEnlTKQ 2218
Cdd:TIGR02169  909 EAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE-LSLEDVQAELQRVEEEIRALE--PVNMLAIQE--YEE 983

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 767908145  2219 IQEKQGQLSE-LDKLLSSFKSLLEEKEQAEIQIKE 2252
Cdd:TIGR02169  984 VLKRLDELKEkRAKLEEERKAILERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 435-708 4.92e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 4.92e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   435 LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQ 514
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   515 clnqsqnfaeemkaKNTSQETMLRDLQEKINQQEnsLTLEKLKLAVADLEKqrdcsqdllKKREHHIEQLNDKLSKTEKE 594
Cdd:TIGR02169  752 --------------EIENVKSELKELEARIEELE--EDLHKLEEALNDLEA---------RLSHSRIPEIQAELSKLEEE 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   595 SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEK-------ENLQSKINHLETCLKTQQIKSHEYNERVRT 667
Cdd:TIGR02169  807 VSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIksiekeiENLNGKKEELEEELEELEAALRDLESRLGD 886

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 767908145   668 LEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAE 708
Cdd:TIGR02169  887 LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 360-588 5.29e-08

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 58.71  E-value: 5.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   360 LEQKLKKLTEDLSCQRQNAESAR--CSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQaknMHNVLQA 437
Cdd:pfam09726  400 LEQDIKKLKAELQASRQTEQELRsqISSLTSLERSLKSELGQLRQENDLLQTKLHNAVSAKQKDKQTVQQ---LEKRLKA 476

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   438 ELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE----LRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Cdd:pfam09726  477 EQEARASAEKQLAEEKKRKKEEEATAARAVALAAASRGEctesLKQRKRELESEIKKLTHDIKLKEEQIRELEIKVQELR 556

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   514 QCLNQSQNFAEEMKAkntsqetmLRDLQEKINQQENSLTLE-KLKL----AVADLEKQRDCSQDLLKKREHHIEQLNDKL 588
Cdd:pfam09726  557 KYKESEKDTEVLMSA--------LSAMQDKNQHLENSLSAEtRIKLdlfsALGDAKRQLEIAQGQIYQKDQEIKDLKQKI 628
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 623-1251 5.46e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 5.46e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   623 KSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHN---VLDSKSVEVETQKLA 699
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQqkqILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   700 YMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNED 779
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   780 HQRSLLAFDQQpamhhsfaniigeqgsmpSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQI 859
Cdd:TIGR02168  401 EIERLEARLER------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   860 KGEIEENLMKAEQMHQSFVAETSQRISKL-----------------------QEDTSAHQNVVAETLSALENKEKEL--- 913
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQARLdslerlqenlegfsegvkallknQSGLSGILGVLSELISVDEGYEAAIeaa 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   914 ------QLLNDKVETEQAEIQELKKSNH-----LLEDSLKELQLLSETLSLEKKEMSSIISLNKRE-------------- 968
Cdd:TIGR02168  543 lggrlqAVVVENLNAAKKAIAFLKQNELgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpklrkalsyll 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   969 -----IEELTQENGTLKEINA-----SLNQEKMN----LIQKSESFANYIDEREKSISELSdqykQEKLILLQRCEETGN 1034
Cdd:TIGR02168  623 ggvlvVDDLDNALELAKKLRPgyrivTLDGDLVRpggvITGGSAKTNSSILERRREIEELE----EKIEELEEKIAELEK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1035 AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAK-------------EHQEFLTKLAFAEERNQNLML 1101
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQleeriaqlskeltELEAEIEELEERLEEAEEELA 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1102 ELETVQQALRSEMTDNQNN---SKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSV 1178
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEElkaLREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767908145  1179 KERESERNQCNfKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQ 1251
Cdd:TIGR02168  859 AEIEELEELIE-ELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR 930
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1796-2570 8.31e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.11  E-value: 8.31e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1796 KVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLeyfSCDHQELLQRVETSEGLNSDLEMHAD 1875
Cdd:TIGR04523   41 KLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKL---KKNKDKINKLNSDLSKINSEIKNDKE 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1876 -KSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELs 1954
Cdd:TIGR04523  118 qKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL- 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1955 vvtSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSsdvSELLKDKTHLQ 2034
Cdd:TIGR04523  197 ---LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK---DEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2035 EKLQSLEKDSQALSltkcELENQIAQLNKEKELLVKESESlqarlsesdyeklnvskaleaalvekgefalrlsstqeev 2114
Cdd:TIGR04523  271 EKQKELEQNNKKIK----ELEKQLNQLKSEISDLNNQKEQ---------------------------------------- 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2115 hqlrRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEM 2194
Cdd:TIGR04523  307 ----DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSY 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2195 ARSLKVFELDLVTLRSEKENLTKQIQEKQGQLseldkllssfKSLLEEKEQAEIQIKEESKTaVEMLQNQLKELNEAVAA 2274
Cdd:TIGR04523  383 KQEIKNLESQINDLESKIQNQEKLNQQKDEQI----------KKLQQEKELLEKEIERLKET-IIKNNSEIKDLTNQDSV 451

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2275 LCGDQEIMKATEQSLDPPIEEehqLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEH 2354
Cdd:TIGR04523  452 KELIIKNLDNTRESLETQLKV---LSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK 528

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2355 AALEAENSKGEVETLKAKIEGMTQslrglELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDF-----ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIK 603

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2435 KsstaMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGK 2514
Cdd:TIGR04523  604 E----IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDII 679

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767908145  2515 QKLEKKDEEIS-----RLKNQI--QDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQ 2570
Cdd:TIGR04523  680 ELMKDWLKELSlhykkYITRMIriKDLPKLEEKYKEIEKELKKLDEFSKELENIIKNFNKKFD 742
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2014-2528 8.32e-08

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 58.37  E-value: 8.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2014 ELLQTLSSDVSELlkdkTHLQEKLQSLEKDSQalsltkcELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKAL 2093
Cdd:PRK01156  173 DVIDMLRAEISNI----DYLEEKLKSSNLELE-------NIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSAL 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2094 EaalvekgefalRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEK------------LKERERENDSLKDK------ 2155
Cdd:PRK01156  242 N-----------ELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELeerhmkiindpvYKNRNYINDYFKYKndienk 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2156 ---VENLERELQMSEEN-QELVILDAENS-----KAEVETLKTQIEEmarsLKVFELDLVTLRSEKENLTKQIQEKQGQL 2226
Cdd:PRK01156  311 kqiLSNIDAEINKYHAIiKKLSVLQKDYNdyikkKSRYDDLNNQILE----LEGYEMDYNSYLKSIESLKKKIEEYSKNI 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2227 SELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSL-----------DPPIEE 2295
Cdd:PRK01156  387 ERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgtTLGEEK 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2296 EHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQ----EHAALEAENSKGEVETLKA 2371
Cdd:PRK01156  467 SNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKiesaRADLEDIKIKINELKDKHD 546

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2372 KIEGMTQSLRGLEL--------------------DVVTIRSEKENLTNELQKEQERISELEI----INSSFENILQEKEQ 2427
Cdd:PRK01156  547 KYEEIKNRYKSLKLedldskrtswlnalavisliDIETNRSRSNEIKKQLNDLESRLQEIEIgfpdDKSYIDKSIREIEN 626

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2428 E------KVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEackaKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQS 2501
Cdd:PRK01156  627 EannlnnKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIP----DLKEITSRINDIEDNLKKSRKALDDAKANRARLES 702

                         570       580
                  ....*....|....*....|....*..
gi 767908145 2502 SVNGLIQEVEDGKQKLEKKDEEISRLK 2528
Cdd:PRK01156  703 TIEILRTRINELSDRINDINETLESMK 729
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 280-988 1.23e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 1.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRttaqydqASTKYTA 359
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER-------LEARLER 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQ-----ASQIK-ENELRRSMEEMKKE--NNLLKSHSEQKAREVCHLE----- 506
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGilgvlSELISvDEGYEAAIEAALGGrlQAVVVENLNAAKKAIAFLKqnelg 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   507 ----AELKNIKQCLNQSQNfaEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADlekQRDCSQDLLKKREHHI- 581
Cdd:TIGR02168  572 rvtfLPLDSIKGTEIQGND--REILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD---DLDNALELAKKLRPGYr 646

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   582 ------EQLNDKLSKTEKESKALLSALelkkkeyeelkeektlfscwksENEKLLTQMESEKENLQSKINHLETCLKTQQ 655
Cdd:TIGR02168  647 ivtldgDLVRPGGVITGGSAKTNSSIL----------------------ERRREIEELEEKIEELEEKIAELEKALAELR 704

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   656 IKSHEYNERVRTLEMDRENLSVEIRNLHNVLdsKSVEVETQKLAYMELQQKAEFSDQKHQKE-----IENMCLKTSQLTG 730
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDL--ARLEAEVEQLEERIAQLSKELTELEAEIEeleerLEEAEEELAEAEA 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   731 QVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEdhQRSLLAFDQQPAMHHSFANIIGEQGSMPSE 810
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE--RRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   811 RSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFV---AETSQRISK 887
Cdd:TIGR02168  861 IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLElrlEGLEVRIDN 940

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   888 LQEDTSAHQNVVAETLSALENK-EKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNK 966
Cdd:TIGR02168  941 LQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020

                          730       740
                   ....*....|....*....|....*..
gi 767908145   967 REIEELTQE-----NGTLKEINASLNQ 988
Cdd:TIGR02168 1021 EAIEEIDREarerfKDTFDQVNENFQR 1047
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2034-2275 1.79e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2034 QEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQaRLSESDYEKLNVsKALEAALVEKGEFALRLSSTQEE 2113
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQ-RLAEYSWDEIDV-ASAEREIAELEAELERLDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQ-MSEENQELVILDAENSKAEvETLKTQIE 2192
Cdd:COG4913   687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEaAEDLARLELRALLEERFAA-ALGDAVER 765

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2193 EMARSLkvfELDLVTLRSEKENLTKQIQEKQGQ----------------------LSELDKLLSS--------FKSLLEE 2242
Cdd:COG4913   766 ELRENL---EERIDALRARLNRAEEELERAMRAfnrewpaetadldadleslpeyLALLDRLEEDglpeyeerFKELLNE 842

                         250       260       270
                  ....*....|....*....|....*....|....
gi 767908145 2243 KEQAEI-QIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG4913   843 NSIEFVaDLLSKLRRAIREIKERIDPLNDSLKRI 876
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2107-2598 2.10e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.04  E-value: 2.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2107 LSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVET 2186
Cdd:pfam05483  284 LKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2187 L----KTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEiQIKEESKTAVEMLQ 2262
Cdd:pfam05483  364 LlrteQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFE-KIAEELKGKEQELI 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2263 NQLKELNEAVAALCGDQEIMKATEQSLDPPIEEehqLRNSIEKlrarleadekkqlcvlQQLKESEHHADLLKGRVENLE 2342
Cdd:pfam05483  443 FLLQAREKEIHDLEIQLTAIKTSEEHYLKEVED---LKTELEK----------------EKLKNIELTAHCDKLLLENKE 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2343 RELEIArtnqeHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNEL-QKEQERISELEIINSSFENI 2421
Cdd:pfam05483  504 LTQEAS-----DMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFiQKGDEVKCKLDKSEENARSI 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2422 LQEKEQEKVQMKEKSSTAMEmLQTQLKELNERVAALHNDQEACKAKEQNLSSQ-------VECLELEKAQLLQGLDEAKN 2494
Cdd:pfam05483  579 EYEVLKKEKQMKILENKCNN-LKKQIENKNKNIEELHQENKALKKKGSAENKQlnayeikVNKLELELASAKQKFEEIID 657

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2495 NYI----VLQSSVNGLIQEVEDGK----QKLEKKDEEISRLKNQIQDQEQLVSK--------LSQVEGEHQLWKEQNLEL 2558
Cdd:pfam05483  658 NYQkeieDKKISEEKLLEEVEKAKaiadEAVKLQKEIDKRCQHKIAEMVALMEKhkhqydkiIEERDSELGLYKNKEQEQ 737

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 767908145  2559 RNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELE 2598
Cdd:pfam05483  738 SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAK 777
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2104-2363 2.23e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 2.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2104 ALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE 2183
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2184 VETLKTQIEEMARSLkvfeldlvtlrsekenltkqiqEKQGQLSELDKLLSSfKSLLEEKEQAEI--QIKEESKTAVEML 2261
Cdd:COG4942    99 LEAQKEELAELLRAL----------------------YRLGRQPPLALLLSP-EDFLDAVRRLQYlkYLAPARREQAEEL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2262 QNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESehhADLLKGRVENL 2341
Cdd:COG4942   156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE---AEELEALIARL 232

                         250       260
                  ....*....|....*....|..
gi 767908145 2342 ERELEIARTNQEHAALEAENSK 2363
Cdd:COG4942   233 EAEAAAAAERTPAAGFAALKGK 254
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1895-2460 2.51e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 2.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1895 ERFLDVENELSRIRSEKASIEHEALYLEADLEvvqteKLCLEKDNENKQKvivcLEEELSVVTSERNQLRGELDTMSKK- 1973
Cdd:COG4913   262 ERYAAARERLAELEYLRAALRLWFAQRRLELL-----EAELEELRAELAR----LEAELERLEARLDALREELDELEAQi 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1974 ----TTALDQLSEKMKEKTQELESHQSEclhciqvaEAEVKEKTELLQ-TLSSDVSELLKDKTHLQEKLQSLEKDSQALS 2048
Cdd:COG4913   333 rgngGDRLEQLEREIERLERELEERERR--------RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALE 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2049 LTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGE---FALRLSSTQEEVHQLRRGIEKL- 2124
Cdd:COG4913   405 EALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAelpFVGELIEVRPEEERWRGAIERVl 484

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2125 ---RVRI---EADEKKQLHIAEKLKERERENdslKDKVENLERELQMS--EENQELVILDAENSKAEvETLKTQIEEMAR 2196
Cdd:COG4913   485 ggfALTLlvpPEHYAAALRWVNRLHLRGRLV---YERVRTGLPDPERPrlDPDSLAGKLDFKPHPFR-AWLEAELGRRFD 560

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2197 SLKVfeLDLVTLRSEKENLTKQIQEKQ-GQLSELDKllssfksllEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG4913   561 YVCV--DSPEELRRHPRAITRAGQVKGnGTRHEKDD---------RRRIRSRYVLGFDNRAKLAALEAELAELEEELAEA 629

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2276 cgdqeimkateqsldppIEEEHQLRNSIEKLRARLEADEKkqlcvLQQLKESEHHADLLKGRVENLERELE-IARTNQEH 2354
Cdd:COG4913   630 -----------------EERLEALEAELDALQERREALQR-----LAEYSWDEIDVASAEREIAELEAELErLDASSDDL 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2355 AALEAenskgEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:COG4913   688 AALEE-----QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762

                         570       580
                  ....*....|....*....|....*.
gi 767908145 2435 KSSTAMEMLQTQLKELNERVAALHND 2460
Cdd:COG4913   763 VERELRENLEERIDALRARLNRAEEE 788
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2130-2715 2.93e-07

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 56.45  E-value: 2.93e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2130 ADEKKQLHIAEKLKERERENDSLKDKVENLERELQmseeNQELVILDAENSKAEVETLKTQIEEMARSLKVFEldlvtlr 2209
Cdd:PRK01156  149 AQRKKILDEILEINSLERNYDKLKDVIDMLRAEIS----NIDYLEEKLKSSNLELENIKKQIADDEKSHSITL------- 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK--EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEq 2287
Cdd:PRK01156  218 KEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKtaESDLSMELEKNNYYKELEERHMKIINDPVYKNRNY- 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2288 sldppIEEEHQLRNSIEKLRARLE---ADEKKQLCVLQQLkesehhADLLKGRVENLERELEIARTNQEHAALEAENSK- 2363
Cdd:PRK01156  297 -----INDYFKYKNDIENKKQILSnidAEINKYHAIIKKL------SVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDy 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2364 ----GEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERI-SELEIINSSFENiLQEKEQEKVQMKEKSST 2438
Cdd:PRK01156  366 nsylKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEInVKLQDISSKVSS-LNQRIRALRENLDELSR 444

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2439 AMEMLQ---------TQLKELNERVAALHNDQEACKakeqnLSSQVECLELEkaqlLQGLDEAKNNYIVLQSSVNG-LIQ 2508
Cdd:PRK01156  445 NMEMLNgqsvcpvcgTTLGEEKSNHIINHYNEKKSR-----LEEKIREIEIE----VKDIDEKIVDLKKRKEYLESeEIN 515

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2509 EVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRN------LTVELEQKIQVLQSKNASLQDT 2582
Cdd:PRK01156  516 KSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRtswlnaLAVISLIDIETNRSRSNEIKKQ 595

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2583 LEVLQSSYKNLENELELTKMDKMSFV----EKVNKMTAKETELQ---REMHEMAQKTAELQEELSGEKNRLAGELQLlle 2655
Cdd:PRK01156  596 LNDLESRLQEIEIGFPDDKSYIDKSIreieNEANNLNNKYNEIQenkILIEKLRGKIDNYKKQIAEIDSIIPDLKEI--- 672

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2656 EIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTK 2715
Cdd:PRK01156  673 TSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIK 732
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1980-2302 3.02e-07

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 56.09  E-value: 3.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1980 LSEKMKEKTQELesHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQalSLTKCELENQIA 2059
Cdd:PRK05771   14 LKSYKDEVLEAL--HELGVVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKK--KVSVKSLEELIK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2060 QLNKEKELLVKESESLQARLSESDYEKlnvsKALEAALVEkgefALRLSSTQEEVHQLRRG----IEKLRVRIEADEKKQ 2135
Cdd:PRK05771   90 DVEEELEKIEKEIKELEEEISELENEI----KELEQEIER----LEPWGNFDLDLSLLLGFkyvsVFVGTVPEDKLEELK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2136 LhIAEKLKEREREND---------SLKDKVENLERELQmSEENQELVILDAENSKAEVETLKTQIEEmarslkvfeldlv 2206
Cdd:PRK05771  162 L-ESDVENVEYISTDkgyvyvvvvVLKELSDEVEEELK-KLGFERLELEEEGTPSELIREIKEELEE------------- 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2207 tLRSEKENLTKQIQEKQGQLSELdkLLSSFKSLLEEKEQAEIQIKE-ESKTAVeMLQ-----NQLKELNEAVAALCGDQE 2280
Cdd:PRK05771  227 -IEKERESLLEELKELAKKYLEE--LLALYEYLEIELERAEALSKFlKTDKTF-AIEgwvpeDRVKKLKELIDKATGGSA 302

                         330       340
                  ....*....|....*....|....*
gi 767908145 2281 IMkateQSLDPPIEEEH---QLRNS 2302
Cdd:PRK05771  303 YV----EFVEPDEEEEEvptKLKNP 323
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1919-2749 3.28e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.52  E-value: 3.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1919 LYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSEC 1998
Cdd:pfam02463  232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1999 LHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQAR 2078
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2079 LSESDYEKLNVSKAleAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVEN 2158
Cdd:pfam02463  392 LKEEELELKSEEEK--EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKK 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2159 LERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS 2238
Cdd:pfam02463  470 SEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAV 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2239 LLEEKEQAEIQIKEESKTAVEMLQNQLKELNEavaalcgdQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQL 2318
Cdd:pfam02463  550 IVEVSATADEVEERQKLVRALTELPLGARKLR--------LLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2319 CVLQQLKESEHHADLLKGRVENLERELEIARTnqehaaleaeNSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLT 2398
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVS----------LEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAK 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2399 NELQKEQERISELEIINSSFENILQEKEQEKVQMKeksstamemLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECL 2478
Cdd:pfam02463  692 EEILRRQLEIKKKEQREKEELKKLKLEAEELLADR---------VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2479 ELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLEL 2558
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2559 RNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNkmtaKETELQREMHEMAQKTAELQEE 2638
Cdd:pfam02463  843 KEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEK----EEKKELEEESQKLNLLEEKENE 918

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2639 LSGEKNRLAGELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNnslkattQILEELKKTKMDN 2718
Cdd:pfam02463  919 IEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLM-------AIEEFEEKEERYN 991

                          810       820       830
                   ....*....|....*....|....*....|.
gi 767908145  2719 LKYVNQLKKENERAQGKMKLLIKSCKQLEEE 2749
Cdd:pfam02463  992 KDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2535-2823 4.23e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 4.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2535 EQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKM 2614
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2615 TAKETELQREMHEMAQKTAELQEELSgeknRLAGELQLLLEEIKSSkyEVEIQTYREKLTSKEECLSSQKLEIDLLKSSK 2694
Cdd:COG1196   315 EERLEELEEELAELEEELEELEEELE----ELEEELEEAEEELEEA--EAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2695 EELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKlliksckQLEEEKEILQKELSQLQAAQEkqktgtvmd 2774
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA-------ELEEEEEEEEEALEEAAEEEA--------- 452

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 767908145 2775 tkvdELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2823
Cdd:COG1196   453 ----ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 2311-2839 4.65e-07

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 55.60  E-value: 4.65e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2311 EADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLK-AKIEGMTQSLRGLELDVVT 2389
Cdd:pfam10174  179 EDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKdTKISSLERNIRDLEDEVQM 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2390 IRSEKENLTNElqkEQERISELEIINSSFENILQEKEQEKVQMKEKSSTaMEMLQTQLKELNERVAALHNDQEACK---- 2465
Cdd:pfam10174  259 LKTNGLLHTED---REEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESE-LLALQTKLETLTNQNSDCKQHIEVLKeslt 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2466 AKEQN---LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQD-QEQLVSKL 2541
Cdd:pfam10174  335 AKEQRaaiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENlQEQLRDKD 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2542 SQVEGehqlwkeqnleLRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNK----MTAK 2617
Cdd:pfam10174  415 KQLAG-----------LKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKenkdLKEK 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2618 ETELQREMHEMAQKTAELQEELSGEKNRLagelqlLLEEIKSSKYEVEIQTyrekltSKEECLssqKLEIDLLKSSKEEL 2697
Cdd:pfam10174  484 VSALQPELTEKESSLIDLKEHASSLASSG------LKKDSKLKSLEIAVEQ------KKEECS---KLENQLKKAHNAEE 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2698 NNslKATTQILEELKKTKMDnlkyVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQ-KTGTVMDTK 2776
Cdd:pfam10174  549 AV--RTNPEINDRIRLLEQE----VARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQmKEQNKKVAN 622

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145  2777 VDELTTEI-KELKETLEEKTKEADEYLDKYCSLLISH--EKLEKAKEMLETQVAHLCSQQSKQDSR 2839
Cdd:pfam10174  623 IKHGQQEMkKKGAQLLEEARRREDNLADNSQQLQLEElmGALEKTRQELDATKARLSSTQQSLAEK 688
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1795-2601 4.88e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 55.82  E-value: 4.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1795 RKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGlnsdLEMHA 1874
Cdd:TIGR00606  241 KSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQ----RTVRE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1875 DKSSREDIGDNVAKVNDSWKE---RFLDVENELSR-----------IRSEKASIEHEALYLEAD---------LEVVQTE 1931
Cdd:TIGR00606  317 KERELVDCQRELEKLNKERRLlnqEKTELLVEQGRlqlqadrhqehIRARDSLIQSLATRLELDgfergpfseRQIKNFH 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1932 KLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSEclhcIQVAEAEVKE 2011
Cdd:TIGR00606  397 TLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKE----LQQLEGSSDR 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2012 KTELLQTLSSDVSELLK-DKTHLQEKLQ----SLEKDSQALSLTKCELENQIAQLNKEK------ELLVKESESLQARLS 2080
Cdd:TIGR00606  473 ILELDQELRKAERELSKaEKNSLTETLKkevkSLQNEKADLDRKLRKLDQEMEQLNHHTttrtqmEMLTKDKMDKDEQIR 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLe 2160
Cdd:TIGR00606  553 KIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDV- 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2161 relqMSEENQElviLDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLL 2240
Cdd:TIGR00606  632 ----CGSQDEE---SDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKL 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2241 ----EEKEQAEIQIKEESKTAVEML------QNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSI---EKLR 2307
Cdd:TIGR00606  705 rlapDKLKSTESELKKKEKRRDEMLglapgrQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpeEESA 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2308 ARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSK--GEVETLKAKIEGMTQSLRGLEL 2385
Cdd:TIGR00606  785 KVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTvvSKIELNRKLIQDQQEQIQHLKS 864

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2386 DVVTIRSEKENLTNELQKEQERISELEIINSSfeniLQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACK 2465
Cdd:TIGR00606  865 KTNELKSEKLQIGTNLQRRQQFEEQLVELSTE----VQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQ 940

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2466 AKEQNLSSQVECLELEKAQLLQGLDEAKNNYIV-LQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQlvsklsqv 2544
Cdd:TIGR00606  941 DKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKqKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKI-------- 1012

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767908145  2545 egeHQLWKEQNLELRNLTVELEQKIQVLQSKNASL-QDTLEVLQSSYKNLENELELTK 2601
Cdd:TIGR00606 1013 ---QERWLQDNLTLRKRENELKEVEEELKQHLKEMgQMQVLQMKQEHQKLEENIDLIK 1067
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2509-2834 6.38e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 6.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2509 EVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTV--------ELEQKIQVLQSKNASLQ 2580
Cdd:TIGR02169  171 KKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGyellkekeALERQKEAIERQLASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2581 DTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKET-ELQREMHEMAQKTAELQEELSgEKNRlagELQLLLEEIKs 2659
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIA-EKER---ELEDAEERLA- 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2660 sKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLL 2739
Cdd:TIGR02169  326 -KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2740 IKSCKQLEEEKEILQKELSQLQAAQEKQKTG-TVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKA 2818
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAGIEAKiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330
                   ....*....|....*.
gi 767908145  2819 KEMLETQVAHLCSQQS 2834
Cdd:TIGR02169  485 LSKLQRELAEAEAQAR 500
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 420-988 7.08e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.33  E-value: 7.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Cdd:COG1196   236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLtLEKLKLAVADLEKQRDCSQDLLKKREH 579
Cdd:COG1196   316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL-LEAEAELAEAEEELEELAEELLEALRA 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  580 HIEQLNDKLSKTEKESKALLSALELKKKeyeelkeektlfscwKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSH 659
Cdd:COG1196   395 AAELAAQLEELEEAEEALLERLERLEEE---------------LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  660 EYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVE-----D 734
Cdd:COG1196   460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEaayeaA 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  735 LEHKLQLLSNEIMDKDRcyQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIgeqgsmpsersEC 814
Cdd:COG1196   540 LEAALAAALQNIVVEDD--EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV-----------AS 606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  815 RLEADQSPKNSAILQNRVDSLEfsLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSA 894
Cdd:COG1196   607 DLREADARYYVLGDTLLGRTLV--AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  895 HQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQ 974
Cdd:COG1196   685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764

                         570
                  ....*....|....
gi 767908145  975 ENGTLKEINASLNQ 988
Cdd:COG1196   765 LERELERLEREIEA 778
COG5022 COG5022
Myosin heavy chain [General function prediction only];
845-1324 8.20e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.08  E-value: 8.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  845 MNSDLQKQCE-ELVQIKGEIEENLMKAEQMHQSFV--AETSQRISKLQEDTsahqnVVAETLSALENKEKELQLLNDKVE 921
Cdd:COG5022   818 CIIKLQKTIKrEKKLRETEEVEFSLKAEVLIQKFGrsLKAKKRFSLLKKET-----IYLQSAQRVELAERQLQELKIDVK 892

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  922 T--------EQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKemssiiSLNKREIEELTQENGTLKEINASLNQEKMNL 993
Cdd:COG5022   893 SisslklvnLELESEIIELKKSLSSDLIENLEFKTELIARLKK------LLNNIDLEEGPSIEYVKLPELNKLHEVESKL 966

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  994 IQKSESFANYIDEREKSISELSDQykQEKLILLQRceetgnAYEDLSQKYKAAQEKNSKLECLLNECTSLcenrKNELEQ 1073
Cdd:COG5022   967 KETSEEYEDLLKKSTILVREGNKA--NSELKNFKK------ELAELSKQYGALQESTKQLKELPVEVAEL----QSASKI 1034

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1074 LKEAFAKEHQefLTKLafaeernQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQEN 1153
Cdd:COG5022  1035 ISSESTELSI--LKPL-------QKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTN 1105

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1154 EQLmkvMKTKHECQNLESEPIRNSVKERESE--RNQCNFKPQM-------DLEVKEISLDSYNAQLVQLEAMLRNKELKL 1224
Cdd:COG5022  1106 RNL---VKPANVLQFIVAQMIKLNLLQEISKflSQLVNTLEPVfqklsvlQLELDGLFWEANLEALPSPPPFAALSEKRL 1182

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1225 QESEKEKEC---LQHELQTIRGDLETsnlqdMQSQEISGL-KDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTTMNK- 1299
Cdd:COG5022  1183 YQSALYDEKsklSSSEVNDLKNELIA-----LFSKIFSGWpRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMs 1257

                         490       500       510
                  ....*....|....*....|....*....|..
gi 767908145 1300 -------LNELEKICEILQAEKYELVTELNDS 1324
Cdd:COG5022  1258 nekllslLNSIDNLLSSYKLEEEVLPATINSL 1289
mukB PRK04863
chromosome partition protein MukB;
2055-2355 8.79e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.96  E-value: 8.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2055 ENQIAQLNKEKELLVKESESLQARLS--ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEklrvRIEADE 2132
Cdd:PRK04863  785 EKRIEQLRAEREELAERYATLSFDVQklQRLHQAFSRFIGSHLAVAFEADPEAELRQLNRRRVELERALA----DHESQE 860

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2133 KKQLHIAEKLKERER------------ENDSLKDKVENLERELQMSEEN---------------QELVILDAENSkaEVE 2185
Cdd:PRK04863  861 QQQRSQLEQAKEGLSalnrllprlnllADETLADRVEEIREQLDEAEEAkrfvqqhgnalaqlePIVSVLQSDPE--QFE 938

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2186 TLK---TQIEEMARSLKVFELDLVTLRSEKENLTkqIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAvemlQ 2262
Cdd:PRK04863  939 QLKqdyQQAQQTQRDAKQQAFALTEVVQRRAHFS--YEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQA----Q 1012

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2263 NQLKELNEAVAALCGD----QEIMKATEQSLDP-----PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADL 2333
Cdd:PRK04863 1013 AQLAQYNQVLASLKSSydakRQMLQELKQELQDlgvpaDSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDN 1092

                         330       340
                  ....*....|....*....|..
gi 767908145 2334 LKGRVENLERELEIARTNQEHA 2355
Cdd:PRK04863 1093 LTKKLRKLERDYHEMREQVVNA 1114
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1787-2272 8.85e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 8.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1787 LHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGL 1866
Cdd:TIGR04523  175 LNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1867 NSDLEMHADK-----SSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNEN 1941
Cdd:TIGR04523  255 LNQLKDEQNKikkqlSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNN 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1942 KQ-----KVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELL 2016
Cdd:TIGR04523  335 KIisqlnEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2017 QTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAA 2096
Cdd:TIGR04523  415 KKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2097 LVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKD--KVENLERELQMSEENQELVI 2174
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFelKKENLEKEIDEKNKEIEELK 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2175 LDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEES 2254
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654

                          490
                   ....*....|....*...
gi 767908145  2255 KTAVEMLQNQLKELNEAV 2272
Cdd:TIGR04523  655 KEIRNKWPEIIKKIKESK 672
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 20-362 9.35e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 9.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   20 IQELEGQLDKLKKEKQQ-----------RQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISH 88
Cdd:COG1196   195 LGELERQLEPLERQAEKaeryrelkeelKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   89 ELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLnpcntpqkifttpltpsqyysgskyEDLK 168
Cdd:COG1196   275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL-------------------------AELE 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  169 EKYNKEVEERKRLEAEVKALQAKKASQtlpQATMNHRDIARHQASSSVFSWQQEktpshlssnsqrtpiRRDFSASYFSG 248
Cdd:COG1196   330 EELEELEEELEELEEELEEAEEELEEA---EAELAEAEEALLEAEAELAEAEEE---------------LEELAEELLEA 391

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  249 EQEVTPSRSTLQIGKRDANSSFFdnsssphLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVE 328
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLE-------RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         330       340       350
                  ....*....|....*....|....*....|....
gi 767908145  329 LIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Cdd:COG1196   465 LAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 410-1208 1.06e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.74  E-value: 1.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   410 LDQECIQMKARLtQELQQAKN-MHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMeemkken 488
Cdd:pfam15921  108 LRQSVIDLQTKL-QEMQMERDaMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMM------- 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   489 nllKSHseqkarevchlEAELKNIKQCLnqsQNFAEEMKAKNTSQETMlrdlqekinqqeNSLTLEKLKLAVADLEKQRD 568
Cdd:pfam15921  180 ---LSH-----------EGVLQEIRSIL---VDFEEASGKKIYEHDSM------------STMHFRSLGSAISKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   569 CSQDLLKKREHHIEqlnDKLSKTEKESKALLSALELKKKEYEELKEektlfscwkSENEKLLTQMESEKENLQSKINHLE 648
Cdd:pfam15921  231 TEISYLKGRIFPVE---DQLEALKSESQNKIELLLQQHQDRIEQLI---------SEHEVEITGLTEKASSARSQANSIQ 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   649 TCLKTQQIKSHEYNE----RVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQ-KLAYMELQQKAEFSDQkhqkeienmcl 723
Cdd:pfam15921  299 SQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQlVLANSELTEARTERDQ----------- 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   724 kTSQLTGQVEDLEHKLqllsneIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLlafDQQPAMHHSFANIIGE 803
Cdd:pfam15921  368 -FSQESGNLDDQLQKL------LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRREL---DDRNMEVQRLEALLKA 437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   804 QGSMPSERSECRLEADQSpKNSAIlqNRVDSLEFSLESQKQMnsdLQKQCEELVQIKGEIE------ENLMKAEQMHQSF 877
Cdd:pfam15921  438 MKSECQGQMERQMAAIQG-KNESL--EKVSSLTAQLESTKEM---LRKVVEELTAKKMTLEssertvSDLTASLQEKERA 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   878 VAETSQRISKLQedtsAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLL-------SET 950
Cdd:pfam15921  512 IEATNAEITKLR----SRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLvgqhgrtAGA 587

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   951 LSLEKKEMSSIISLNKREIEELT----QENGTLKEINASLNQEKMNLIQksesFANYIDEREKSISELsdqyKQEKLILL 1026
Cdd:pfam15921  588 MQVEKAQLEKEINDRRLELQEFKilkdKKDAKIRELEARVSDLELEKVK----LVNAGSERLRAVKDI----KQERDQLL 659

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1027 QRCEETGNAYEDLSQKYKAAQE----KNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQE--FLTKLAFAEERN---- 1096
Cdd:pfam15921  660 NEVKTSRNELNSLSEDYEVLKRnfrnKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSdgHAMKVAMGMQKQitak 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1097 QNLMLELETVQQALRSEMTDNQNNS---KSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQL------MKVMKTKHECQ 1167
Cdd:pfam15921  740 RGQIDALQSKIQFLEEAMTNANKEKhflKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLkekvanMEVALDKASLQ 819

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 767908145  1168 NLESEPIRNSvKERESERnqcnFKPQMDLEVKEISLDSYNA 1208
Cdd:pfam15921  820 FAECQDIIQR-QEQESVR----LKLQHTLDVKELQGPGYTS 855
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 879-1155 1.59e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  879 AETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSnhlLEDSLKELQLLSETlslekkem 958
Cdd:COG1196   242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE---LARLEQDIARLEER-------- 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  959 ssiISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYED 1038
Cdd:COG1196   311 ---RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1039 LSQKYKAAQEKNSKLECLLNECTSLcENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEmTDNQ 1118
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEAL-LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL-LELL 465

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 767908145 1119 NNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQ 1155
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2033-2500 2.86e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 2.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2033 LQEKLQSLEKDS-QALSLTKCELENQIAQLnKEKELLVKESESLQARLSESDYEKLNVSKALEAA--LVEKGEFALRLSS 2109
Cdd:COG4717    51 LEKEADELFKPQgRKPELNLKELKELEEEL-KEAEEKEEEYAELQEELEELEEELEELEAELEELreELEKLEKLLQLLP 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2110 TQEEVHQLRRGIEKLRVRIEADEKKQlhiaEKLKERERENDSLKDKVENLERELqmseenQELVILDAENSKAEVETLKT 2189
Cdd:COG4717   130 LYQELEALEAELAELPERLEELEERL----EELRELEEELEELEAELAELQEEL------EELLEQLSLATEEELQDLAE 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2190 QIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Cdd:COG4717   200 ELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVL 279

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLR--------ARLEADEKKQLCVLQQLKESEHHADLLKGRVENL 2341
Cdd:COG4717   280 FLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEeeeleellAALGLPPDLSPEELLELLDRIEELQELLREAEEL 359

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2342 ERELEIARTNQEHAALEAENSKGEVETLKAKIEgmtqslrgleldvvtIRSEKENLTNELQKEQERISEleiINSSFENI 2421
Cdd:COG4717   360 EEELQLEELEQEIAALLAEAGVEDEEELRAALE---------------QAEEYQELKEELEELEEQLEE---LLGELEEL 421

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2422 LQEKEQEKVQMKEKSstamemLQTQLKELNERVAALHNDQEACKAKEQNLSSQ--VECLELEKAQLLQGLDEAKNNYIVL 2499
Cdd:COG4717   422 LEALDEEELEEELEE------LEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQELEELKAELRELAEEWAAL 495


                  .
gi 767908145 2500 Q 2500
Cdd:COG4717   496 K 496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2355-2598 4.37e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 4.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2355 AALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2435 KSSTAMEMLQTQLKELNERVAALHndqeackakeqnLSSQVECLELEKAQllQGLDEAKNNYIVLQSSVNGLIQEVEDGK 2514
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALY------------RLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2515 QKLEKKDEEISRLKNQIQDQEQLVSKLsqvegehqlwKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLE 2594
Cdd:COG4942   157 ADLAELAALRAELEAERAELEALLAEL----------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226


                  ....
gi 767908145 2595 NELE 2598
Cdd:COG4942   227 ALIA 230
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
809-1235 5.26e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.37  E-value: 5.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  809 SERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQsfVAETSQRISKL 888
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE--YLDELREIEKR 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  889 QEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLkelQLLSETLSLEKKEMSSIISLNKRE 968
Cdd:PRK03918  316 LSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK---AKKEELERLKKRLTGLTPEKLEKE 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  969 IEELTQENGTLKEINASLNQEKMNLIQKsesfanyIDEREKSISELSdqyKQEKLILLQRCEETGNAYEDLSQKYKAaqe 1048
Cdd:PRK03918  393 LEELEKAKEEIEEEISKITARIGELKKE-------IKELKKAIEELK---KAKGKCPVCGRELTEEHRKELLEEYTA--- 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1049 KNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQefLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGL 1128
Cdd:PRK03918  460 ELKRIEKELKEIEEKERKLRKELRELEKVLKKESE--LIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKL 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1129 KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCN---------FKPQMDLEVK 1199
Cdd:PRK03918  538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEpfyneylelKDAEKELERE 617

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 767908145 1200 EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQ 1235
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEKRLEELRKELEELE 653
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2271-2484 5.34e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 5.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2271 AVAALCGDQEIMKATEQSLDppieeehQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL----- 2345
Cdd:COG4942    11 LALAAAAQADAAAEAEAELE-------QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELaalea 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2346 EIARTNQEHAALEAE-----------------NSKGEVETLKAKIEGMTQSLRGLELdVVTIRSEKENLTNELQKEQERI 2408
Cdd:COG4942    84 ELAELEKEIAELRAEleaqkeelaellralyrLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAEL 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145 2409 SELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQ 2484
Cdd:COG4942   163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1914-2598 5.64e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.53  E-value: 5.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1914 IEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKK--------TTALDQLSEKMK 1985
Cdd:pfam12128  239 IRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQwkekrdelNGELSAADAAVA 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1986 EKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQAL-SLTKCELENQIAQLNKE 2064
Cdd:pfam12128  319 KDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDK 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2065 KELlVKESESLQARLSESDYEklnvskALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVrieadekKQLHIAEKLKE 2144
Cdd:pfam12128  399 LAK-IREARDRQLAVAEDDLQ------ALESELREQLEAGKLEFNEEEYRLKSRLGELKLRL-------NQATATPELLL 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2145 RERENDSLKDKVenleRELQmseenqelvildaENSKAEVETLktqieemarslkvfELDLVTLRSEKENLTKQIQEKQG 2224
Cdd:pfam12128  465 QLENFDERIERA----REEQ-------------EAANAEVERL--------------QSELRQARKRRDQASEALRQASR 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2225 QLSELDKLLssfkslleekEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCgDQEIMKATEqsLDPPIEEEHQL-RNSI 2303
Cdd:pfam12128  514 RLEERQSAL----------DELELQLFPQAGTLLHFLRKEAPDWEQSIGKVI-SPELLHRTD--LDPEVWDGSVGgELNL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2304 EKLRARLEAdekkqlcvlQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGL 2383
Cdd:pfam12128  581 YGVKLDLKR---------IDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNA 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2384 ELDvvtirsekenltnelqkeQERISEleiinssfenilqEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEA 2463
Cdd:pfam12128  652 RLD------------------LRRLFD-------------EKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQA 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2464 CKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIV-----LQSSVNGLIQEVE-DGKQKLEKKD---EEISRLKNQIQDQ 2534
Cdd:pfam12128  701 WLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKaaiaaRRSGAKAELKALEtWYKRDLASLGvdpDVIAKLKREIRTL 780

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767908145  2535 EQLVSKLSQVEGE----HQLWKEQNLELR-NLTVELEQkiqvLQSKNASLQDTLEVLQSSYKNLENELE 2598
Cdd:pfam12128  781 ERKIERIAVRRQEvlryFDWYQETWLQRRpRLATQLSN----IERAISELQQQLARLIADTKLRRAKLE 845
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2422-2611 6.65e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.94  E-value: 6.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2422 LQEKEQEKVQMKEKS-----STAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQ--GLDEAKN 2494
Cdd:COG3206   191 LEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRA 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2495 NYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVskLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS 2574
Cdd:COG3206   271 QLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI--LASLEAELEALQAREASLQAQLAQLEARLAELPE 348

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 767908145 2575 KNA---SLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2611
Cdd:COG3206   349 LEAelrRLEREVEVARELYESLLQRLEEARLAEALTVGNV 388
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2365-2801 7.15e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 7.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFEnILQEKEQEKVQMKEksstamemLQ 2444
Cdd:COG4717    75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP-LYQELEALEAELAE--------LP 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2445 TQLKELNERVAALHNDQEACKAKEQNLSSQ----VECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKK 2520
Cdd:COG4717   146 ERLEELEERLEELRELEEELEELEAELAELqeelEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2521 DEEISRLKNQIQDQEQ------------LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQS 2588
Cdd:COG4717   226 EEELEQLENELEAAALeerlkearllllIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAE 305

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2589 SYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLagELQLLLEEIKS--SKYEVE- 2665
Cdd:COG4717   306 ELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELEQEIAAllAEAGVEd 383

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2666 IQTYREKLTSKEEClssQKLEiDLLKSSKEELNNSLKATTQILEELKKTkmdnlkyvnQLKKENERAQGKMKlliksckQ 2745
Cdd:COG4717   384 EEELRAALEQAEEY---QELK-EELEELEEQLEELLGELEELLEALDEE---------ELEEELEELEEELE-------E 443

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145 2746 LEEEKEILQKELSQLQAAQEKQKTgtvmDTKVDELTTEIKELKETLEEKTKEADEY 2801
Cdd:COG4717   444 LEEELEELREELAELEAELEQLEE----DGELAELLQELEELKAELRELAEEWAAL 495
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2225-2496 7.33e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 7.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2225 QLSELDKLLSSFksLLEEKEqaeiqikeeSKTAVEMLQNQLKELNEAvaalcgDQEIMKATEQ--SLDPpIEEEHQlrns 2302
Cdd:COG4913   205 PIGDLDDFVREY--MLEEPD---------TFEAADALVEHFDDLERA------HEALEDAREQieLLEP-IRELAE---- 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2303 iEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELeiARTNQEHAALEAenskgEVETLKAKIEGMTQSLRG 2382
Cdd:COG4913   263 -RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAEL--ARLEAELERLEA-----RLDALREELDELEAQIRG 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2383 LELDvvtirsEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQE 2462
Cdd:COG4913   335 NGGD------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALA 408

                         250       260       270
                  ....*....|....*....|....*....|....
gi 767908145 2463 ACKAKEQNLSSQVECLELEKAQLLQGldeaKNNY 2496
Cdd:COG4913   409 EAEAALRDLRRELRELEAEIASLERR----KSNI 438
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 879-1114 8.04e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 8.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  879 AETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEM 958
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  959 SSIISLNKREIeeltQENGTLKEINASLNQEKMNLIQKSesfANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYED 1038
Cdd:COG4942   103 KEELAELLRAL----YRLGRQPPLALLLSPEDFLDAVRR---LQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145 1039 LSQKYKAAQEKNSKLECLLNEctslcenRKNELEQLKEAFAKEHQEfLTKLAFAEERNQNLMLELETVQQALRSEM 1114
Cdd:COG4942   176 LEALLAELEEERAALEALKAE-------RQKLLARLEKELAELAAE-LAELQQEAEELEALIARLEAEAAAAAERT 243
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 280-502 8.39e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 8.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  360 LEQKLKKLTeDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439
Cdd:COG4942   102 QKEELAELL-RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767908145  440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREV 502
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
PLN02939 PLN02939
transferase, transferring glycosyl groups
 2463-2820 8.54e-06

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 51.83  E-value: 8.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2463 ACKAKEQNLSSQVECLELEKAQLLQGLDEAK--NNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQ--EQLV 2538
Cdd:PLN02939   34 SCRARRRGFSSQQKKKRGKNIAPKQRSSNSKlqSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAiaAIDN 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2539 SKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMdKMSFVEKVNKMTAKE 2618
Cdd:PLN02939  114 EQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEM-RLSETDARIKLAAQE 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2619 ---TELQREMHEMAQKTAELQEELSGE-KNRLAGELQLLLEEIKSSKyeVEIQTYREKLTS---KEECLSSQKLEIDLLK 2691
Cdd:PLN02939  193 kihVEILEEQLEKLRNELLIRGATEGLcVHSLSKELDVLKEENMLLK--DDIQFLKAELIEvaeTEERVFKLEKERSLLD 270

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2692 SSKEELNNSLKATTQILEELKKTKMDNL-KYVNQLKKENERAQGKMKLLIKSCKQLEEekeiLQKELSQLQAAQEKQKTG 2770
Cdd:PLN02939  271 ASLRELESKFIVAQEDVSKLSPLQYDCWwEKVENLQDLLDRATNQVEKAALVLDQNQD----LRDKVDKLEASLKEANVS 346

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767908145 2771 TVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLIS-HEKLEKAKE 2820
Cdd:PLN02939  347 KFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEfQDTLSKLKE 397
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1827-2412 1.01e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 51.62  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1827 ELEKIVGELKKENSDLSEKLEYFSCDHQELLQRV-ETSEGLNSDLEMHADKSSR-EDIGDNVAKVNDSWKErfLDVENEL 1904
Cdd:COG5022   879 LAERQLQELKIDVKSISSLKLVNLELESEIIELKkSLSSDLIENLEFKTELIARlKKLLNNIDLEEGPSIE--YVKLPEL 956

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1905 SRIRSEKASIehealyleadlevvqtEKLCLEKDNENKQKVIvcLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKM 1984
Cdd:COG5022   957 NKLHEVESKL----------------KETSEEYEDLLKKSTI--LVREGNKANSELKNFKKELAELSKQYGALQESTKQL 1018

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1985 KEKTQELESHQSEcLHCIQVAEAEVKEKTEllqtLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE 2064
Cdd:COG5022  1019 KELPVEVAELQSA-SKIISSESTELSILKP----LQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLL 1093

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2065 KELLVKESESLQARL-SESDYEKLNVSKALEAALV-EKGEFALRLSSTQEEVHQLRRGIEKLR--VRIEADEKKQLHI-- 2138
Cdd:COG5022  1094 KTINVKDLEVTNRNLvKPANVLQFIVAQMIKLNLLqEISKFLSQLVNTLEPVFQKLSVLQLELdgLFWEANLEALPSPpp 1173

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2139 -AEKLKERERENDSLKDKVENLERELQM-SEENQELVILDAENSKAEVETLKTQIEEMarslkvfeLDLVTLRSEKENLT 2216
Cdd:COG5022  1174 fAALSEKRLYQSALYDEKSKLSSSEVNDlKNELIALFSKIFSGWPRGDKLKKLISEGW--------VPTEYSTSLKGFNN 1245

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2217 KQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEE 2296
Cdd:COG5022  1246 LNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATEVNYNSEELDD 1325

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2297 HQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLK-------GRVENLERELEIArtNQEHAALEAENSKGEVETL 2369
Cdd:COG5022  1326 WCREFEISDVDEELEELIQAVKVLQLLKDDLNKLDELLDacyslnpAEIQNLKSRYDPA--DKENNLPKEILKKIEALLI 1403

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 767908145 2370 KAKIEGMTQSLRGLELDVVTIRSEKEN---LTNELQKEQERISELE 2412
Cdd:COG5022  1404 KQELQLSLEGKDETEVHLSEIFSEEKSlisLDRNSIYKEEVLSSLS 1449
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1766-2194 1.14e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1846 LEyfscdhqellqrvetseglnsDLEMHadkssREDIGDNVAKVNDSWKERFLDVENELSRIRsekasiEHEALyleadl 1925
Cdd:PRK02224  407 LG---------------------NAEDF-----LEELREERDELREREAELEATLRTARERVE------EAEAL------ 448

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1926 evvQTEKLCLEKDNENKQKVIVCL----EEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEkTQELESHQSECLHC 2001
Cdd:PRK02224  449 ---LEAGKCPECGQPVEGSPHVETieedRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEEL 524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS- 2080
Cdd:PRK02224  525 IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2081 ESDYEKLNVSKALEAALVEkgEFALRLSSTQEEVHQLRRG-----IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDK 2155
Cdd:PRK02224  605 EDEIERLREKREALAELND--ERRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 767908145 2156 VENLERELQMSEENQELviLDA-ENSKAEVETLKTQIEEM 2194
Cdd:PRK02224  683 IGAVENELEELEELRER--REAlENRVEALEALYDEAEEL 720
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
425-949 1.18e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  425 LQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE---QKARE 501
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKE 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  502 VCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLK-----------LAVADLEKQRDCS 570
Cdd:PRK03918  247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYeeyldelreieKRLSRLEEEINGI 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  571 QDLLKKREH---HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSEN----EKLLTQMESEKENLQSK 643
Cdd:PRK03918  327 EERIKELEEkeeRLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTpeklEKELEELEKAKEEIEEE 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  644 INHLETCLKTQQIKSHEYNERVRTL---------------EMDRENLSVEIRnlhnvLDSKSVEVETQKLAYMELQQKAE 708
Cdd:PRK03918  407 ISKITARIGELKKEIKELKKAIEELkkakgkcpvcgreltEEHRKELLEEYT-----AELKRIEKELKEIEEKERKLRKE 481

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  709 FSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKD-RCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAF 787
Cdd:PRK03918  482 LRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKaEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAEL 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  788 ----DQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAI-LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 862
Cdd:PRK03918  562 ekklDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLeLKDAEKELEREEKELKKLEEELDKAFEELAETEKR 641

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  863 IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLK 942
Cdd:PRK03918  642 LEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALE 721


                  ....*..
gi 767908145  943 ELQLLSE 949
Cdd:PRK03918  722 RVEELRE 728
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2133-2601 1.29e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2133 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVildaENSKAEVETLKTQIEEMARSLKVFEL--DLVTLRS 2210
Cdd:COG4717    64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL----EELEAELEELREELEKLEKLLQLLPLyqELEALEA 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALcgdqeimkateqsld 2290
Cdd:COG4717   140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL--------------- 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2291 ppIEEEHQLRNSIEKLRARLEADEKKqlcvLQQLKESEHHADLLKgRVENLERELEIARtnqehAALEAENSKGEVETLK 2370
Cdd:COG4717   205 --QQRLAELEEELEEAQEELEELEEE----LEQLENELEAAALEE-RLKEARLLLLIAA-----ALLALLGLGGSLLSLI 272

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2371 AKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINS-SFENILQEKEQEKVQMKEKSSTAMEMLQtQLKE 2449
Cdd:COG4717   273 LTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEeELEELLAALGLPPDLSPEELLELLDRIE-ELQE 351

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2450 LNERVAALHN--DQEACKAKEQNLSSQVECLELE----KAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKD-- 2521
Cdd:COG4717   352 LLREAEELEEelQLEELEQEIAALLAEAGVEDEEelraALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEle 431

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2522 EEISRLKNQIQDQEQLVSKLSQVEGEHQlWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTK 2601
Cdd:COG4717   432 EELEELEEELEELEEELEELREELAELE-AELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYR 510
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 280-768 1.33e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Cdd:TIGR04523  206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   360 LEQKLKKLTEDLSCQRQNAESarcsleqkikEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNmhnvLQAEL 439
Cdd:TIGR04523  286 LEKQLNQLKSEISDLNNQKEQ----------DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ----LKKEL 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   440 DKLTSVKQQLENNLEEFKQKLcraeqafqASQIKENE-LRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQ 518
Cdd:TIGR04523  352 TNSESENSEKQRELEEKQNEI--------EKLKKENQsYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   519 SQNFAEEMKAKNTSQETMLRDLQEKINQQEnsLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Cdd:TIGR04523  424 LEKEIERLKETIIKNNSEIKDLTNQDSVKE--LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   599 LSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKS--HEYNERVRTLEMDRENLS 676
Cdd:TIGR04523  502 NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKeiDEKNKEIEELKQTQKSLK 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   677 VEIRNLHNVLDSKSVEVETQKlaymelqqkaefsdqkhqKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDL 756
Cdd:TIGR04523  582 KKQEEKQELIDQKEKEKKDLI------------------KEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643

                          490
                   ....*....|..
gi 767908145   757 HAEYESLRDLLK 768
Cdd:TIGR04523  644 KQEVKQIKETIK 655
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1940-2129 1.33e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1940 ENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEkMKEKTQELESHQSEclhciqVAEAEvKEKTELLQTl 2019
Cdd:COG4913   613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE-YSWDEIDVASAERE------IAELE-AELERLDAS- 683

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2020 SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNvsKALEAALVE 2099
Cdd:COG4913   684 SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE--ERFAAALGD 761

                         170       180       190
                  ....*....|....*....|....*....|
gi 767908145 2100 KGEFALRlSSTQEEVHQLRRGIEKLRVRIE 2129
Cdd:COG4913   762 AVERELR-ENLEERIDALRARLNRAEEELE 790
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2106-2309 1.34e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2106 RLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKEREREND--SLKDKVENLERELQmseenqelvilDAENSKAE 2183
Cdd:COG4913   618 ELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDvaSAEREIAELEAELE-----------RLDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2184 VETLKTQIEEmarslkvfeldlvtLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEE-KEQAEIQIKEESKTAVEMLQ 2262
Cdd:COG4913   687 LAALEEQLEE--------------LEAELEELEEELDELKGEIGRLEKELEQAEEELDElQDRLEAAEDLARLELRALLE 752

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 767908145 2263 NQLKELNEAVAAlcgdQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 2309
Cdd:COG4913   753 ERFAAALGDAVE----RELRENLEERIDALRARLNRAEEELERAMRA 795
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2215-2439 1.41e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 1.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2215 LTKQIQEKQGQLSELDKLLSSFKslleeKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIE 2294
Cdd:COG3206   180 LEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPD 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2295 EEHQLRNS--IEKLRARLEADEKKqlcvLQQLKE--SEHHADL--LKGRVENLERELEiARTNQEHAALEAEnskgeVET 2368
Cdd:COG3206   255 ALPELLQSpvIQQLRAQLAELEAE----LAELSAryTPNHPDViaLRAQIAALRAQLQ-QEAQRILASLEAE-----LEA 324

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767908145 2369 LKAKIEGMTQSLRGLELDVVTIrsekenltNELQKEQERIS-ELEIINSSFENILQEKEQEKVQMKEKSSTA 2439
Cdd:COG3206   325 LQAREASLQAQLAQLEARLAEL--------PELEAELRRLErEVEVARELYESLLQRLEEARLAEALTVGNV 388
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2320-2476 2.00e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 48.77  E-value: 2.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2320 VLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE--NL 2397
Cdd:COG1579    15 LDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeAL 94

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767908145 2398 TNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVE 2476
Cdd:COG1579    95 QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1902-2134 2.20e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1902 NELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKttaLDQLS 1981
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE---IAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1982 EKMKEKTQELEShqseclhciQVAEAEVKEKTELLQTL--SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIA 2059
Cdd:COG4942    97 AELEAQKEELAE---------LLRALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767908145 2060 QLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKK 2134
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1790-2057 2.73e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 2.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1790 IEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELE-KIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGlns 1868
Cdd:TIGR02169  746 LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEaRLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLN--- 822

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1869 dlEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVC 1948
Cdd:TIGR02169  823 --RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE 900

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1949 LEEELSVVTSERNQLRGEL-DTMSKKTTALDQLSEKMKEKTQELEShqSECLHCIQVAEAEVKEKTELLQTLSS------ 2021
Cdd:TIGR02169  901 LERKIEELEAQIEKKRKRLsELKAKLEALEEELSEIEDPKGEDEEI--PEEELSLEDVQAELQRVEEEIRALEPvnmlai 978

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 767908145  2022 -DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ 2057
Cdd:TIGR02169  979 qEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1766-2268 2.81e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 2.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1766 QEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Cdd:COG1196   287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1846 LEYfscDHQELLQRVETSEGLNSDLEMHADKSSREDIG-DNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEAD 1924
Cdd:COG1196   367 LLE---AEAELAEAEEELEELAEELLEALRAAAELAAQlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1925 LEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQ------ELESHQSEC 1998
Cdd:COG1196   444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvkaalLLAGLRGLA 523

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1999 LHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTkcelenqIAQLNKEKELLVKESESLQAR 2078
Cdd:COG1196   524 GAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT-------FLPLDKIRARAALAAALARGA 596

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2079 LSEsdyeklnVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVEN 2158
Cdd:COG1196   597 IGA-------AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2159 LERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS 2238
Cdd:COG1196   670 LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                         490       500       510
                  ....*....|....*....|....*....|
gi 767908145 2239 LLEEKEQAEIQIKEESKTAVEMLQNQLKEL 2268
Cdd:COG1196   750 EEALEELPEPPDLEELERELERLEREIEAL 779
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1936-2363 2.98e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 2.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1936 EKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALD------QLSEKMKEKTQELESHQSEcLHCIQVAEAEV 2009
Cdd:COG4717    87 EEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyqeleALEAELAELPERLEELEER-LEELRELEEEL 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2010 KEKTELLQTLSSDVSELLKDKTHLQEK-LQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARL-SESDYEKL 2087
Cdd:COG4717   166 EELEAELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELeAAALEERL 245

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2088 N------VSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQL-HIAEKLKERERENDSLKDKVENLE 2160
Cdd:COG4717   246 KearlllLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLgKEAEELQALPALEELEEEELEELL 325

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2161 RELQMSEENQELVILDAENSKAEVETLKTQIEEMARslkvfELDLVTLRSEKENLTKQIQEKQgqlseldklLSSFKSLL 2240
Cdd:COG4717   326 AALGLPPDLSPEELLELLDRIEELQELLREAEELEE-----ELQLEELEQEIAALLAEAGVED---------EEELRAAL 391

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2241 EEKEQAEiQIKEESKTAVEMLQNQLKELNEAVAALcgDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEAdEKKQLCV 2320
Cdd:COG4717   392 EQAEEYQ-ELKEELEELEEQLEELLGELEELLEAL--DEEELEEELEELEEELEELEEELEELREELAELEA-ELEQLEE 467

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 767908145 2321 LQQLKESEHHADLLKGRVENLERE---LEIARTNQEHAALEAENSK 2363
Cdd:COG4717   468 DGELAELLQELEELKAELRELAEEwaaLKLALELLEEAREEYREER 513
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 446-1090 3.06e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.97  E-value: 3.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   446 KQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEE 525
Cdd:TIGR00618  165 KKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAY 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   526 MKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREH-----HIEQLNDKLSKTEKESKALLS 600
Cdd:TIGR00618  245 LTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHikavtQIEQQAQRIHTELQSKMRSRA 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   601 ALELKKKEYEELKEEKtlfscwksENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIR 680
Cdd:TIGR00618  325 KLLMKRAAHVKQQSSI--------EEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQ 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   681 NLHNVLDSKSVE---VETQKLAYMELQQK--AEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKD----- 750
Cdd:TIGR00618  397 SLCKELDILQREqatIDTRTSAFRDLQGQlaHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEReqqlq 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   751 ------RCYQDLHAEYESLRDLLKSKDASLVTNEDH--------------QRSLLAFDQQPAMHHSFANIIGEQGSMPSE 810
Cdd:TIGR00618  477 tkeqihLQETRKKAVVLARLLELQEEPCPLCGSCIHpnparqdidnpgplTRRMQRGEQTYAQLETSEEDVYHQLTSERK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   811 R----SECRLEADQSPKNSAILQNRV-DSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAE-QMHQSFVAETSQR 884
Cdd:TIGR00618  557 QraslKEQMQEIQQSFSILTQCDNRSkEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpEQDLQDVRLHLQQ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   885 ISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISl 964
Cdd:TIGR00618  637 CSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEE- 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   965 NKREIEELTQENGTLKeinASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK 1044
Cdd:TIGR00618  716 YDREFNEIENASSSLG---SDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNR 792

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*.
gi 767908145  1045 AAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLA 1090
Cdd:TIGR00618  793 LREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLE 838
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 918-1184 3.32e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 3.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   918 DKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEInasLNQEKMNLIQKS 997
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER---LEELEEDLSSLE 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   998 ESFANYIDEREKSISELsdQYKQEKLILLQrcEETGNAYEDLSQ--------KYKAAQEKNSKLECLLNEctslCENRKN 1069
Cdd:TIGR02169  751 QEIENVKSELKELEARI--EELEEDLHKLE--EALNDLEARLSHsripeiqaELSKLEEEVSRIEARLRE----IEQKLN 822

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1070 ELEQLKEAFAKEHQEFLTKLAFAEER---NQNLMLELETVQQALRSEMTDNQNNSK---SEAGGLKQEIMTLKEEQNKMQ 1143
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIDLKEQiksIEKEIENLNGKKEELEEELEELEAALRdleSRLGDLKKERDELEAQLRELE 902

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 767908145  1144 KEVNDL---LQENEQLMKVMKTKHECQNLESEPIRNSVKERESE 1184
Cdd:TIGR02169  903 RKIEELeaqIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI 946
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2389-2826 3.47e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.63  E-value: 3.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2389 TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKE 2468
Cdd:TIGR04523   44 TIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLE 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2469 QNLSSQVECLELEKAQLLQGLDEAKN---NYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVE 2545
Cdd:TIGR04523  124 VELNKLEKQKKENKKNIDKFLTEIKKkekELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLL 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2546 GEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREM 2625
Cdd:TIGR04523  204 SNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKI 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2626 HEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKyEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATT 2705
Cdd:TIGR04523  284 KELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQ-EKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2706 QILEElKKTKMDNLKYVNQLKKENeraqgkmklliksCKQLEEEKEILQKELS-QLQAAQEKQKTGTVMDTKVDELTTEI 2784
Cdd:TIGR04523  363 RELEE-KQNEIEKLKKENQSYKQE-------------IKNLESQINDLESKIQnQEKLNQQKDEQIKKLQQEKELLEKEI 428

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 767908145  2785 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV 2826
Cdd:TIGR04523  429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL 470
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2082-2275 3.96e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.67  E-value: 3.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2082 SDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2162 ELQMSEENQEL--VILDAENSKA---EVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSF 2236
Cdd:COG3883    94 ALYRSGGSVSYldVLLGSESFSDfldRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767908145 2237 KSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG3883   174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAA 212
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1917-2232 4.33e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 49.16  E-value: 4.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1917 EALYleaDLEVVQTEKLCLEKDNENKQKVivclEEELSVVTSERNQLRGEldtMSKKTTALDQLSEKMKEKTQELESHQS 1996
Cdd:PRK05771   23 EALH---ELGVVHIEDLKEELSNERLRKL----RSLLTKLSEALDKLRSY---LPKLNPLREEKKKVSVKSLEELIKDVE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1997 ECLHCIqvaEAEVKEKTELLQTLSSDVSELLKDKTHLqEKLQSLEKDSQALsLTKCELENQIAQLNKEKELLVK-ESESL 2075
Cdd:PRK05771   93 EELEKI---EKEIKELEEEISELENEIKELEQEIERL-EPWGNFDLDLSLL-LGFKYVSVFVGTVPEDKLEELKlESDVE 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2076 QARLSESDYEKLNVskaleAALVEKgefalRLSSTQEEVhqLRR-GIEKLRVRIEAD-----EKKQLHIAEKLKEREREN 2149
Cdd:PRK05771  168 NVEYISTDKGYVYV-----VVVVLK-----ELSDEVEEE--LKKlGFERLELEEEGTpseliREIKEELEEIEKERESLL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2150 DSLKDKVENLERELQMSEEnqelvILDAENSKAEVEtlktqiEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSEL 2229
Cdd:PRK05771  236 EELKELAKKYLEELLALYE-----YLEIELERAEAL------SKFLKTDKTFAIEGWVPEDRVKKLKELIDKATGGSAYV 304


                  ...
gi 767908145 2230 DKL 2232
Cdd:PRK05771  305 EFV 307
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 2067-2434 6.02e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 48.35  E-value: 6.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2067 LLVKESESLQARLSESDYEKLNVSKALEAA-----------LVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQ 2135
Cdd:pfam07888   24 LVVPRAELLQNRLEECLQERAELLQAQEAAnrqrekekeryKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKY 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2136 LHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEldlvtlrSEKENL 2215
Cdd:pfam07888  104 KELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEE-------AERKQL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2216 TKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTavemLQNQLKELNEAVAalcgdqeimkateqsldppieE 2295
Cdd:pfam07888  177 QAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITT----LTQKLTTAHRKEA---------------------E 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2296 EHQLRNSIEKLRARLEADEKKQLCVLQQLKE-----SEHHADLLKGRVENLERELEIA------RTNQEHAALEAENSKG 2364
Cdd:pfam07888  232 NEALLEELRSLQERLNASERKVEGLGEELSSmaaqrDRTQAELHQARLQAAQLTLQLAdaslalREGRARWAQERETLQQ 311

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767908145  2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQ--------ERISELEIINSSFENILQEKEQEKVQMKE 2434
Cdd:pfam07888  312 SAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREKdcnrvqlsESRRELQELKASLRVAQKEKEQLQAEKQE 389
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1926-2765 6.10e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.02  E-value: 6.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1926 EVVQTEKLCLEKDNENKQKVivclEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVA 2005
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKA----ESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHEL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2006 EAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDyE 2085
Cdd:pfam01576   81 ESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLE-E 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2086 KLNVSKALEAALVEKGEFALRLSSTQEEVhqlrrgIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDkvenlerelQM 2165
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAM------ISDLEERLKKEEKGRQELEKAKRKLEGESTDLQE---------QI 224

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2166 SEENQELVILDAENSKAEvetlktqiEEMARSLKVFELDlvtlRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQ 2245
Cdd:pfam01576  225 AELQAQIAELRAQLAKKE--------EELQAALARLEEE----TAQKNNALKKIRELEAQISELQEDLESERAARNKAEK 292

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2246 AEIQIKEEsktaVEMLQNQLKELNEAVAAlcgDQEIMKATEQSLDppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLK 2325
Cdd:pfam01576  293 QRRDLGEE----LEALKTELEDTLDTTAA---QQELRSKREQEVT---ELKKALEEETRSHEAQLQEMRQKHTQALEELT 362

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2326 ESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRG-----------LELDVVTIRSEK 2394
Cdd:pfam01576  363 EQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQArlseserqraeLAEKLSKLQSEL 442

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2395 ENLTNELQKEQERISELEIINSSFENILQEKeQEKVQMKEKSSTAmemLQTQLKELNERVAALHNDQEACKAKEQNLSSQ 2474
Cdd:pfam01576  443 ESVSSLLNEAEGKNIKLSKDVSSLESQLQDT-QELLQEETRQKLN---LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQ 518

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2475 VECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQ--------------IQDQEQLVSK 2540
Cdd:pfam01576  519 LSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTknrlqqelddllvdLDHQRQLVSN 598

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2541 LS--QVEGEHQLWKEQNLELRNL---------TVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVE 2609
Cdd:pfam01576  599 LEkkQKKFDQMLAEEKAISARYAeerdraeaeAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGK 678

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2610 KVNKMTAKETELQREMHEMAQKTAELQEELSGEKN---RLAGELQLLleeikSSKYEVEIQTYREKLTSKEECLSSQKLE 2686
Cdd:pfam01576  679 NVHELERSKRALEQQVEEMKTQLEELEDELQATEDaklRLEVNMQAL-----KAQFERDLQARDEQGEEKRRQLVKQVRE 753

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767908145  2687 IDLlksskeELNNSLKATTQILEELKKTKMDnlkyVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQE 2765
Cdd:pfam01576  754 LEA------ELEDERKQRAQAVAAKKKLELD----LKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRD 822
CENP-F_leu_zip pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, ...
 1893-2018 6.73e-05

Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; Cenp-F, a centromeric kinetochore, microtubule-binding protein consisting of two 1,600-amino acid-long coils, is essential for the full functioning of the mitotic checkpoint pathway. There are several leucine-rich repeats along the sequence of LEK1 that are considered to be zippers, though they do not appear to be binding DNA directly in this instance.


Pssm-ID: 463102 [Multi-domain]  Cd Length: 140  Bit Score: 45.37  E-value: 6.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1893 WKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSK 1972
Cdd:pfam10473    1 DEKKQLHVLEKLKESERKADSLKDKVENLERELEMSEENQELAILEAENSKAEVETLKAEIEEMAQNLRDLELDLVTLRS 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 767908145  1973 KTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT 2018
Cdd:pfam10473   81 EKENLTKELQKKQERVSELESLNSSLENLLEEKEQEKVQMKEESKT 126
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 2151-2739 7.38e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 48.58  E-value: 7.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2151 SLKDKVENLERELQMSEENQELVILDAEnskAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELD 2230
Cdd:pfam05557    6 ESKARLSQLQNEKKQMELEHKRARIELE---KKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKK 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2231 KLLSSFKSLLEEKEQAEIQIKEESKTavemLQNQLKELneavaalcgdQEIMKATEQSLDPPIEEEHQLRNSIEKLRARL 2310
Cdd:pfam05557   83 KYLEALNKKLNEKESQLADAREVISC----LKNELSEL----------RRQIQRAELELQSTNSELEELQERLDLLKAKA 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2311 EADEKKQLCVLQQLKESEHHADllkgRVENLERELEiartNQEHAALEAENSKGEV------ETLKAKIEGMTQSLRGLE 2384
Cdd:pfam05557  149 SEAEQLRQNLEKQQSSLAEAEQ----RIKELEFEIQ----SQEQDSEIVKNSKSELaripelEKELERLREHNKHLNENI 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2385 LDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQE-KEQEKV-QMKEKSSTAMEMLQTQLKELNERVAALhndqe 2462
Cdd:pfam05557  221 ENKLLLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQElQSWVKLaQDTGLNLRSPEDLSRRIEQLQQREIVL----- 295

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2463 ackaKEQNLSSQVECLELEKAQLLqgldeaknnyivLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQI----QDQEQLV 2538
Cdd:pfam05557  296 ----KEENSSLTSSARQLEKARRE------------LEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVllltKERDGYR 359

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2539 SKLSQVEGEHQLwKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQ---SSYKNLEN--ELELTKMDKMSFVEKVNK 2613
Cdd:pfam05557  360 AILESYDKELTM-SNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEeelGGYKQQAQtlERELQALRQQESLADPSY 438

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2614 MTAKETELQREMHEMAQKTAELQEELSGEKNRLAG-ELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKS 2692
Cdd:pfam05557  439 SKEEVDSLRRKLETLELERQRLREQKNELEMELERrCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKR 518

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 767908145  2693 SKEELNNSLKATTQILEElkkTKMDNLKYVNQLKKENERAQGKMKLL 2739
Cdd:pfam05557  519 LLKKLEDDLEQVLRLPET---TSTMNFKEVLDLRKELESAELKNQRL 562
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2508-2749 7.56e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 7.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2508 QEVEDGKQKLEKKDEEISRLKNQIQDQEQlvsKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQ 2587
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKK---EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2588 SSYKNLENELE--LTKMDKMSFVEKVNKMTAKETELQremhemAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKyeVE 2665
Cdd:COG4942    97 AELEAQKEELAelLRALYRLGRQPPLALLLSPEDFLD------AVRRLQYLKYLAPARREQAEELRADLAELAALR--AE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2666 IQTYREKLTSKEECLSSQKLEIDLLKSSKEELnnslkattqiLEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQ 2745
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALKAERQKL----------LARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                  ....
gi 767908145 2746 LEEE 2749
Cdd:COG4942   239 AAER 242
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1795-2100 7.58e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 7.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1795 RKVE--SLLNEMKELDSKLH-LQEVQlmtkIEAC---IELEKIvGELKKENSDLSEKLEyfscdhqeLLQRVETSEGLNS 1868
Cdd:PRK05771    7 KKVLivTLKSYKDEVLEALHeLGVVH----IEDLkeeLSNERL-RKLRSLLTKLSEALD--------KLRSYLPKLNPLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1869 DLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEAL------YLEADLEVVQTEKLC------LE 1936
Cdd:PRK05771   74 EEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIErlepwgNFDLDLSLLLGFKYVsvfvgtVP 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1937 KDNENKQKVIVclEEELSVVTSERNQlrgeldtmsKKTTALDQLSEKMKEKTQELESHqseclhciQVAEAEVKEK---T 2013
Cdd:PRK05771  154 EDKLEELKLES--DVENVEYISTDKG---------YVYVVVVVLKELSDEVEEELKKL--------GFERLELEEEgtpS 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2014 ELLQTLSSDVSELLKDKTHLQEKLQSL-EKDSQALSLTKCELENQIAQLNKEKELLvkESE---SLQARLSESDYEKLnv 2089
Cdd:PRK05771  215 ELIREIKEELEEIEKERESLLEELKELaKKYLEELLALYEYLEIELERAEALSKFL--KTDktfAIEGWVPEDRVKKL-- 290

                         330
                  ....*....|.
gi 767908145 2090 SKALEAALVEK 2100
Cdd:PRK05771  291 KELIDKATGGS 301
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2214-2650 7.66e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.80  E-value: 7.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2214 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEML---QNQLKeLNEAVAALCGDQEIM--KATEQS 2288
Cdd:COG3096   289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLnlvQTALR-QQEKIERYQEDLEELteRLEEQE 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2289 LDPPIEEEHQLRNSIEKLRARLEADE-KKQLCVLQQ-LKESEHHADLLKGRVENLEReleiARTNQEHAALEAENSKGEV 2366
Cdd:COG3096   368 EVVEEAAEQLAEAEARLEAAEEEVDSlKSQLADYQQaLDVQQTRAIQYQQAVQALEK----ARALCGLPDLTPENAEDYL 443

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2367 ETLKAKIEGMTQSLRGLEldvvtirsEKENLTNELQKEQERISELeiinssFENILQEKEQEkvqmkEKSSTAMEMLQT- 2445
Cdd:COG3096   444 AAFRAKEQQATEEVLELE--------QKLSVADAARRQFEKAYEL------VCKIAGEVERS-----QAWQTARELLRRy 504

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2446 -QLKELNERVAALhndQEACKAKEQNLSSQVECLELEKaQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEI 2524
Cdd:COG3096   505 rSQQALAQRLQQL---RAQLAELEQRLRQQQNAERLLE-EFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR 580

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2525 SRLKNQIQDQEQLVSKLSQVEGEhqlWkeqnlelrnltVELEQKIQVLQSK-NASLQDTLEVLQSSYKNLENELELTkmd 2603
Cdd:COG3096   581 SELRQQLEQLRARIKELAARAPA---W-----------LAAQDALERLREQsGEALADSQEVTAAMQQLLEREREAT--- 643

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 767908145 2604 kmsfVEKvNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGEL 2650
Cdd:COG3096   644 ----VER-DELAARKQALESQIERLSQPGGAEDPRLLALAERLGGVL 685
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 18-371 7.85e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 7.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQV 97
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    98 NFQEGQLNSGKKQIEKLEQELKRCKSELERSQQaaqsadvslnpcntpqkifttpltpsqyysgsKYEDLKEKYNKEVEE 177
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEAEIEELEA--------------------------------QIEQLKEELKALREA 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   178 RKRLEAEVKALQAKKASQTLPQAtMNHRDIARHQASSSVFSWQQEKTPSHLSSNsqrtpirrdfSASYFSGEQEVTPSRS 257
Cdd:TIGR02168  805 LDELRAELTLLNEEAANLRERLE-SLERRIAATERRLEDLEEQIEELSEDIESL----------AAEIEELEELIEELES 873

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   258 TLQigkrdanSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIE-KEKVL 336
Cdd:TIGR02168  874 ELE-------ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLS 946

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 767908145   337 NKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDL 371
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1900-2412 9.56e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.50  E-value: 9.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1900 VENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERN------QLRGELDTMSKK 1973
Cdd:TIGR00606  575 LEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDeesdleRLKEEIEKSSKQ 654

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1974 TTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALsLTKCE 2053
Cdd:TIGR00606  655 RAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEM-LGLAP 733

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2054 LENQIAQLnKEKEL---------LVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALrLSSTQEEVHQLRRGIEKL 2124
Cdd:TIGR00606  734 GRQSIIDL-KEKEIpelrnklqkVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTI-MERFQMELKDVERKIAQQ 811

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2125 RVRIEADEKKQLHiaEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELD 2204
Cdd:TIGR00606  812 AAKLQGSDLDRTV--QQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQ 889

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2205 LVTLRSEKENLTKQIQEKQGQLSELDKLLssfKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALcgdQEIMKA 2284
Cdd:TIGR00606  890 LVELSTEVQSLIREIKDAKEQDSPLETFL---EKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYM---KDIENK 963

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2285 TEQSLDppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKG 2364
Cdd:TIGR00606  964 IQDGKD---DYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQH 1040

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*...
gi 767908145  2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELE 2412
Cdd:TIGR00606 1041 LKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFK 1088
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1765-2094 9.61e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 9.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1765 NQEDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSE 1844
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1845 KLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREdigdnvakvNDSWKERFLDVENELSRIRSEKASiehealyLEAD 1924
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE---------LKALREALDELRAELTLLNEEAAN-------LRER 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1925 LEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQV 2004
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2005 AEAEVKEKTELLQ-------TLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTK--------CELENQIAQLNKEKELL- 2068
Cdd:TIGR02168  906 LESKRSELRRELEelreklaQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALenkieddeEEARRRLKRLENKIKELg 985

                          330       340       350
                   ....*....|....*....|....*....|..
gi 767908145  2069 ------VKESESLQARLSESDYEKLNVSKALE 2094
Cdd:TIGR02168  986 pvnlaaIEEYEELKERYDFLTAQKEDLTEAKE 1017
PRK01156 PRK01156
chromosome segregation protein; Provisional
 863-1351 9.74e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.36  E-value: 9.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  863 IEENLMKAEQMHQSFVAETSQrISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLK 942
Cdd:PRK01156  164 LERNYDKLKDVIDMLRAEISN-IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALN 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  943 ELQLLSET---LSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQyk 1019
Cdd:PRK01156  243 ELSSLEDMknrYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAE-- 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1020 qeklilLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKN------ELEQLKEAFAKEHQEFLTKLAFAE 1093
Cdd:PRK01156  321 ------INKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDynsylkSIESLKKKIEEYSKNIERMSAFIS 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1094 ERNQNLMLELETVqQALRSEMTDNQNNSKSEAGGLKQEIMTLKeeQNKMQKEVNDLLQENEQLMKVMKTkhecqNLESEP 1173
Cdd:PRK01156  395 EILKIQEIDPDAI-KKELNEINVKLQDISSKVSSLNQRIRALR--ENLDELSRNMEMLNGQSVCPVCGT-----TLGEEK 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1174 IRNSVKERESERNQCNFK-PQMDLEVKEIslDSYNAQLVQLEAMLRNKELKLQESEKEK-ECLQHELQTIRGDLET-SNL 1250
Cdd:PRK01156  467 SNHIINHYNEKKSRLEEKiREIEIEVKDI--DEKIVDLKKRKEYLESEEINKSINEYNKiESARADLEDIKIKINElKDK 544

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1251 QDMQSQEISGLKDCEI-DAEEKYISGPHELSTSQNdnahlqCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECI 1329
Cdd:PRK01156  545 HDKYEEIKNRYKSLKLeDLDSKRTSWLNALAVISL------IDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYID 618

                         490       500
                  ....*....|....*....|..
gi 767908145 1330 TATRKMAEEVGKLLNEVKILND 1351
Cdd:PRK01156  619 KSIREIENEANNLNNKYNEIQE 640
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2564-2771 1.02e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2564 ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEK 2643
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2644 NRLA------------GELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEEL 2711
Cdd:COG4942   104 EELAellralyrlgrqPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767908145 2712 KKTKmdnlKYVNQLKKENE----RAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGT 2771
Cdd:COG4942   184 EEER----AALEALKAERQkllaRLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 284-1020 1.02e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.04  E-value: 1.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   284 KAQNQELRNKINELELRLQGhekemkgqvnkfqeLQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTaleQK 363
Cdd:TIGR00618  186 FAKKKSLHGKAELLTLRSQL--------------LTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLT---QK 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   364 LKKLTEDLSCQRQNAESARcsleQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLT 443
Cdd:TIGR00618  249 REAQEEQLKKQQLLKQLRA----RIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRA 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   444 SVKQQLENNLEEfKQKLCRAEQAFQASQIKENELRRSMEEMKkennLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFA 523
Cdd:TIGR00618  325 KLLMKRAAHVKQ-QSSIEEQRRLLQTLHSQEIHIRDAHEVAT----SIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLC 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   524 EEMkakntsqeTMLRDLQEKINQQENSLTLEKLKLAVAdlEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALE 603
Cdd:TIGR00618  400 KEL--------DILQREQATIDTRTSAFRDLQGQLAHA--KKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   604 LKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLkTQQIKSHEYNERVRTLEMDRENLSVEIRNLH 683
Cdd:TIGR00618  470 EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPAR-QDIDNPGPLTRRMQRGEQTYAQLETSEEDVY 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   684 NVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMclktSQLTGQVEDLEHKLQLLSNEimdKDRCYQDLHAEYESL 763
Cdd:TIGR00618  549 HQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDI----PNLQNITVRLQDLTEKLSEA---EDMLACEQHALLRKL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   764 RDLLKSKDASLVTNEDHQRSLLAfdqqpamhhsFANIIGEQGSMPSERSEcrleadqspknSAILQNRVDSLEfSLESQK 843
Cdd:TIGR00618  622 QPEQDLQDVRLHLQQCSQELALK----------LTALHALQLTLTQERVR-----------EHALSIRVLPKE-LLASRQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   844 QMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSfVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 923
Cdd:TIGR00618  680 LALQKMQSEKEQLTYWKEMLAQCQTLLRELETH-IEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKA 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   924 QAEIQELKKSNHL-LEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEngtLKEINASLNQEKMNLIQKSESFAN 1002
Cdd:TIGR00618  759 RTEAHFNNNEEVTaALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE---IPSDEDILNLQCETLVQEEEQFLS 835

                          730
                   ....*....|....*...
gi 767908145  1003 YIDEREKSISELSDQYKQ 1020
Cdd:TIGR00618  836 RLEEKSATLGEITHQLLK 853
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2013-2246 1.04e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2013 TELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKA 2092
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2093 LEAalvEKGEFALRLSstqeeVHQLRRGIEKLRVRIEADEKKQL--------HIAEKLKERERENDSLKDKVENLERELQ 2164
Cdd:COG4942    99 LEA---QKEELAELLR-----ALYRLGRQPPLALLLSPEDFLDAvrrlqylkYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2165 MSEENQELVILDAENSKAEVETLKTQIEEMarslkvfeldLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKE 2244
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKL----------LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 767908145 2245 QA 2246
Cdd:COG4942   241 ER 242
PLN02939 PLN02939
transferase, transferring glycosyl groups
 2144-2476 1.34e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 47.97  E-value: 1.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2144 ERERENDSLKDkvenlERELQMSEENQElvildaenSKAEVETLKTQIEEMARSL------KVFEL-DLVTLRSEKENLT 2216
Cdd:PLN02939  103 QRDEAIAAIDN-----EQQTNSKDGEQL--------SDFQLEDLVGMIQNAEKNIlllnqaRLQALeDLEKILTEKEALQ 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2217 KQIQEKQGQLSELDkllssfkslleekeqAEIQIKEESKTAVEMLQNQLKEL-NEAVAALCGDQEIMKATEQSLDPPIEE 2295
Cdd:PLN02939  170 GKINILEMRLSETD---------------ARIKLAAQEKIHVEILEEQLEKLrNELLIRGATEGLCVHSLSKELDVLKEE 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2296 EHQLRNSIEKLRARLE--ADEKKQLCVLqqlkESEHhaDLLKGRVENLERELEIARTNQehaaleAENSKGEVETLKAKI 2373
Cdd:PLN02939  235 NMLLKDDIQFLKAELIevAETEERVFKL----EKER--SLLDASLRELESKFIVAQEDV------SKLSPLQYDCWWEKV 302

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2374 EGMtqslrGLELDVVTIRSEKENLTneLQKEQERISELEIINSSFEnilqekeqeKVQMKEKSSTAMEMLQTQLKELNER 2453
Cdd:PLN02939  303 ENL-----QDLLDRATNQVEKAALV--LDQNQDLRDKVDKLEASLK---------EANVSKFSSYKVELLQQKLKLLEER 366

                         330       340       350
                  ....*....|....*....|....*....|.
gi 767908145 2454 VAALHND--------QEACKAKEQNLSSQVE 2476
Cdd:PLN02939  367 LQASDHEihsyiqlyQESIKEFQDTLSKLKE 397
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2355-2767 1.35e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 1.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2355 AALEAENSKgeveTLKAKIEGMTQSLRGLELD----VVTIRSEKENLTNELQKEQERISELEIINSSFEnilqeKEQEKV 2430
Cdd:TIGR00618  182 ALMEFAKKK----SLHGKAELLTLRSQLLTLCtpcmPDTYHERKQVLEKELKHLREALQQTQQSHAYLT-----QKREAQ 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2431 QMKEKSSTAMEMLQTQLKELNERVAALHNDQEackakEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEV 2510
Cdd:TIGR00618  253 EEQLKKQQLLKQLRARIEELRAQEAVLEETQE-----RINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2511 EDGK--QKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLE---- 2584
Cdd:TIGR00618  328 MKRAahVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDilqr 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2585 -------------VLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQ 2651
Cdd:TIGR00618  408 eqatidtrtsafrDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2652 LLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENER 2731
Cdd:TIGR00618  488 KKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQE 567

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 767908145  2732 AQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQ 2767
Cdd:TIGR00618  568 IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKL 603
PLN02939 PLN02939
transferase, transferring glycosyl groups
 2002-2309 1.41e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 47.59  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSE 2081
Cdd:PLN02939  102 MQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSE 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2082 SDyEKLNVSkALEAALVEKGEfalrlsstqeevHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Cdd:PLN02939  182 TD-ARIKLA-AQEKIHVEILE------------EQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKA 247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2162 EL-QMSEENQELVILDAENS--KAEVETLKTQ-IEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFK 2237
Cdd:PLN02939  248 ELiEVAETEERVFKLEKERSllDASLRELESKfIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDQNQ 327

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767908145 2238 SLLEEKEQAEIQIKE-----ESKTAVEMLQNQLKELNEAVAAlcGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRAR 2309
Cdd:PLN02939  328 DLRDKVDKLEASLKEanvskFSSYKVELLQQKLKLLEERLQA--SDHEIHSYIQLYQESIKEFQDTLSKLKEESKKR 402
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 896-1232 1.87e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 1.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   896 QNVVAETLSALENKEKELQL---------LNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSsiislnk 966
Cdd:TIGR02168  208 QAEKAERYKELKAELRELELallvlrleeLREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELE------- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   967 REIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELsdqyKQEKLILLQRCEETGNAYEDLSQKYKAA 1046
Cdd:TIGR02168  281 EEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL----ESKLDELAEELAELEEKLEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1047 QEKNSKLECLLNECTSLCENRKNELEQLKEAFAkehqefltklafaeernqnlmleletvqqALRSEMTDNQNnskseag 1126
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVA-----------------------------QLELQIASLNN------- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1127 glkqEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKT----KHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEIS 1202
Cdd:TIGR02168  401 ----EIERLEARLERLEDRRERLQQEIEELLKKLEEaelkELQAELEELEEELEELQEELERLEEALEELREELEEAEQA 476

                          330       340       350
                   ....*....|....*....|....*....|
gi 767908145  1203 LDSYNAQLVQLEAMLRNKELKLQESEKEKE 1232
Cdd:TIGR02168  477 LDAAERELAQLQARLDSLERLQENLEGFSE 506
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 2393-2796 1.91e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.02  E-value: 1.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLS 2472
Cdd:pfam05483  280 QDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTC 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2473 SQVECLELEKAQLLQGLDEAKNNYIVLQSSVNgliqEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWK 2552
Cdd:pfam05483  360 SLEELLRTEQQRLEKNEDQLKIITMELQKKSS----ELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELK 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2553 EQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKT 2632
Cdd:pfam05483  436 GKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLEL 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2633 AELQEELSGEKNRLAGEL-QLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEE- 2710
Cdd:pfam05483  516 KKHQEDIINCKKQEERMLkQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENk 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2711 ---LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELsqlqaAQEKQKTGTVMDTKVDELTTEIKEL 2787
Cdd:pfam05483  596 cnnLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELEL-----ASAKQKFEEIIDNYQKEIEDKKISE 670


                   ....*....
gi 767908145  2788 KETLEEKTK 2796
Cdd:pfam05483  671 EKLLEEVEK 679
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1852-2820 2.03e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 47.35  E-value: 2.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1852 DHQELLQR--VETSEGLNSDLEMHADKSSREDIGDNVAKVNDS---WKERFLDVENELSRIRSEKASIEHEA-----LYL 1921
Cdd:TIGR01612  510 DFMELYKPdeVPSKNIIGFDIDQNIKAKLYKEIEAGLKESYELaknWKKLIHEIKKELEEENEDSIHLEKEIkdlfdKYL 589

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1922 EADLEVVQTEKLCLE---------KDNENKQKVIvcleeELSVVTSERNQLRGELDTMSKK-------------TTALDQ 1979
Cdd:TIGR01612  590 EIDDEIIYINKLKLElkekiknisDKNEYIKKAI-----DLKKIIENNNAYIDELAKISPYqvpehlknkdkiySTIKSE 664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1980 LSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLK--DKTHLQEKLQSLEKDSQALSLTKCELENQ 2057
Cdd:TIGR01612  665 LSKIYEDDIDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQnmETATVELHLSNIENKKNELLDIIVEIKKH 744

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2058 I-AQLNKEKELLVKESESLQARLSE--SDYEK----LNVSKALEAALVEKGEFALRLSSTQEEvhQLRRGIEKLRVRIEA 2130
Cdd:TIGR01612  745 IhGEINKDLNKILEDFKNKEKELSNkiNDYAKekdeLNKYKSKISEIKNHYNDQINIDNIKDE--DAKQNYDKSKEYIKT 822

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2131 DEKKQLHIAEKLKERERENDSLKDKVENLerelqMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:TIGR01612  823 ISIKEDEIFKIINEMKFMKDDFLNKVDKF-----INFENNCKEKIDSEHEQFAELTNKIKAEISDDKLNDYEKKFNDSKS 897

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2211 EKENLTKQIQEKQGQLSELDKLlssfkslleekeQAEIQIKEESKTAVEML---QNQLKE-LNEAVAALCGDQEIMKA-- 2284
Cdd:TIGR01612  898 LINEINKSIEEEYQNINTLKKV------------DEYIKICENTKESIEKFhnkQNILKEiLNKNIDTIKESNLIEKSyk 965

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2285 ------------------TEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLcvLQQLKESEHHADLLKGRVENLERE-- 2344
Cdd:TIGR01612  966 dkfdntlidkineldkafKDASLNDYEAKNNELIKYFNDLKANLGKNKENML--YHQFDEKEKATNDIEQKIEDANKNip 1043

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2345 -LEIA-RTNQEHAALEAENSKGE-VETLKAKIegmtqsLRGLELDVVTIRSEKENLT----NELQKEQ--ERISELEIIN 2415
Cdd:TIGR01612 1044 nIEIAiHTSIYNIIDEIEKEIGKnIELLNKEI------LEEAEINITNFNEIKEKLKhynfDDFGKEEniKYADEINKIK 1117

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2416 SSFENILQEKEQ---EKVQMKEKSSTAMEMLQTQLKELnERVA--ALHNDQ-EACKAKEQNLSSQV-------------- 2475
Cdd:TIGR01612 1118 DDIKNLDQKIDHhikALEEIKKKSENYIDEIKAQINDL-EDVAdkAISNDDpEEIEKKIENIVTKIdkkkniydeikkll 1196

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2476 -ECLELEKAQllQGLDEAKNNYIVLQSSVNGLIqevedgkqkLEKKDEEISRLKNQIQDQEQLVSKLSQVegehqlwKEQ 2554
Cdd:TIGR01612 1197 nEIAEIEKDK--TSLEEVKGINLSYGKNLGKLF---------LEKIDEEKKKSEHMIKAMEAYIEDLDEI-------KEK 1258

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2555 NLELRN---LTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKEtELQREMHEMAQK 2631
Cdd:TIGR01612 1259 SPEIENemgIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDIKK-ELQKNLLDAQKH 1337

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2632 TAELQEELSGEKNrLAGELQL-----LLEEIKSSKYEVE----------------IQTYREKlTSKEECLSSQKLEID-- 2688
Cdd:TIGR01612 1338 NSDINLYLNEIAN-IYNILKLnkikkIIDEVKEYTKEIEennknikdeldkseklIKKIKDD-INLEECKSKIESTLDdk 1415

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2689 ----LLKSSKEELNNSLKATTQILEELKKTKMDNlKYVNQLKKENERAQGKMKLLIKSCKqlEEEKEILQKELSQLQAAQ 2764
Cdd:TIGR01612 1416 dideCIKKIKELKNHILSEESNIDTYFKNADENN-ENVLLLFKNIEMADNKSQHILKIKK--DNATNDHDFNINELKEHI 1492

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145  2765 EKQKTgtvMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHeKLEKAKE 2820
Cdd:TIGR01612 1493 DKSKG---CKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKN-KFAKTKK 1544
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 828-1352 2.16e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 2.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSA-L 906
Cdd:pfam15921  147 LQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiL 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   907 ENKEKELQLLNDKVETEQAEIQELKKsnhlleDSLKELQLLsetLSLEKKEMSSIISLNKREIEELTQENGTLKEINASL 986
Cdd:pfam15921  227 RELDTEISYLKGRIFPVEDQLEALKS------ESQNKIELL---LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSI 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   987 nQEKMNLIQKSESFANYIDEREksISELSDQYKQekliLLQRCEETGNAYED-LSQKYKAAQEKNSKLECLLNECTSLCE 1065
Cdd:pfam15921  298 -QSQLEIIQEQARNQNSMYMRQ--LSDLESTVSQ----LRSELREAKRMYEDkIEELEKQLVLANSELTEARTERDQFSQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1066 NRKNELEQLKEAFAKEHQEfLTKLAFAEERNQNLMlELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEE-QNKMQK 1144
Cdd:pfam15921  371 ESGNLDDQLQKLLADLHKR-EKELSLEKEQNKRLW-DRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMER 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1145 EVNDLLQENEQLMKVMKTKHECQNLEsEPIRNSVKE--------RESERNQCNFKPQmdLEVKEISLDSYNAQLVQLEAM 1216
Cdd:pfam15921  449 QMAAIQGKNESLEKVSSLTAQLESTK-EMLRKVVEEltakkmtlESSERTVSDLTAS--LQEKERAIEATNAEITKLRSR 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1217 LRNKELKLQESEKEKECLQH---ELQTIRGDL-ETSNLQDMQSQEISGLKdcEIDAEEKYISGPHELSTSQ-----NDN- 1286
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNvqtECEALKLQMaEKDKVIEILRQQIENMT--QLVGQHGRTAGAMQVEKAQlekeiNDRr 603

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767908145  1287 ---AHLQCSLQTTMNKLNELEKICEILQAEKYELVtelnDSRSECITATRKMAEEVGKLLNEVKILNDD 1352
Cdd:pfam15921  604 lelQEFKILKDKKDAKIRELEARVSDLELEKVKLV----NAGSERLRAVKDIKQERDQLLNEVKTSRNE 668
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 844-1156 2.23e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   844 QMNSDLQKQCEELVQIKGEIEENlmkaeqmhQSFVAETSQRISKLQEDT------------------SAHQNVVAETLSA 905
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERL--------DLIIDEKRQQLERLRRERekaeryqallkekreyegYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   906 LENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLE-----KKEMSSI---ISLNKREIEELTQENG 977
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrvKEKIGELeaeIASLERSIAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   978 TLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQY---KQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLE 1054
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYaelKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1055 CLLNECTSLCENRKNELEQLKEAFAKEHQEfltkLAFAEERNQNLMLELETVQQALRsEMTDNQNNSKSEAGGLKQEIMT 1134
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADLNAA----IAGIEAKINELEEEKEDKALEIK-KQEWKLEQLAADLSKYEQELYD 473

                          330       340
                   ....*....|....*....|..
gi 767908145  1135 LKEEQNKMQKEVNDLLQENEQL 1156
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRELAEA 495
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2191-2441 2.60e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2191 IEEMARslkvfeLDLVTLRSEKENLTKQIQE----------KQGQ----------LSELDKLLSSFKSLLEEkeqAEIQI 2250
Cdd:PRK05771    3 PVRMKK------VLIVTLKSYKDEVLEALHElgvvhiedlkEELSnerlrklrslLTKLSEALDKLRSYLPK---LNPLR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2251 KEESKTAVEMLQNQLKELNEAVAALcgdqeimkatEQSLDPPIEEEHQLRNSIEKLRARLEADEK-KQLCVLQQLKESEH 2329
Cdd:PRK05771   74 EEKKKVSVKSLEELIKDVEEELEKI----------EKEIKELEEEISELENEIKELEQEIERLEPwGNFDLDLSLLLGFK 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2330 HADLLKGRVeNLERELEIARTNQEHAALEAENSKGE----VETLKAKIEGMTQSLRGLELDVVTIrSEKENLTNELQKEQ 2405
Cdd:PRK05771  144 YVSVFVGTV-PEDKLEELKLESDVENVEYISTDKGYvyvvVVVLKELSDEVEEELKKLGFERLEL-EEEGTPSELIREIK 221

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 767908145 2406 ERI----SELEIINSSFENILQEKEQEKVQMKEKSSTAME 2441
Cdd:PRK05771  222 EELeeieKERESLLEELKELAKKYLEELLALYEYLEIELE 261
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 1982-2584 2.75e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 46.72  E-value: 2.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1982 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKdsqalsltkcelenqiaql 2061
Cdd:PRK10246  191 EQHKSARTELEKLQAQASGVALLTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTR------------------- 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2062 nkeKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALR-LSSTQEE----VHQLRRGIEKLRVRIEADEKKQL 2136
Cdd:PRK10246  252 ---LDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQLRpHWERIQEqsaaLAHTRQQIEEVNTRLQSTMALRA 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2137 HI----AEKLKERERENDSLKDKVENLERELQMSEE--NQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Cdd:PRK10246  329 RIrhhaAKQSAELQAQQQSLNTWLAEHDRFRQWNNElaGWRAQFSQQTSDREQLRQWQQQLTHAEQKLNALPAITLTLTA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2211 EKenlTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEesktAVEMLQNQLKELNEAVAALcgDQEIMKATEQSLD 2290
Cdd:PRK10246  409 DE---VAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQV----AIQNVTQEQTQRNAALNEM--RQRYKEKTQQLAD 479

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2291 -PPIEEEHQLRNSIEKLRARLEADEKKQLCvlqqlKESEHHAdllkgrVENLErELEIARTNQEHAALEAE--NSKGEVE 2367
Cdd:PRK10246  480 vKTICEQEARIKDLEAQRAQLQAGQPCPLC-----GSTSHPA------VEAYQ-ALEPGVNQSRLDALEKEvkKLGEEGA 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2368 TLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELqkeQERISELEIINSSFENI---LQEKEQEKVQMKEKSSTamEMLQ 2444
Cdd:PRK10246  548 ALRGQLDALTKQLQRDESEAQSLRQEEQALTQQW---QAVCASLNITLQPQDDIqpwLDAQEEHERQLRLLSQR--HELQ 622

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2445 TQLKELNERVAALhndQEACKAKEQNLSSQVECLELekaQLLQGLDEAKnnyivlqssvngLIQEVEDGKQKLEKKDEEI 2524
Cdd:PRK10246  623 GQIAAHNQQIIQY---QQQIEQRQQQLLTALAGYAL---TLPQEDEEAS------------WLATRQQEAQSWQQRQNEL 684

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767908145 2525 SRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQNLELRNLTVELEQKIQVLQSknaslQDTLE 2584
Cdd:PRK10246  685 TALQNRIQQLTPLLETLPQsddlPHSEETVALDNWRQVHEQCLSLHSQLQTLQQ-----QDVLE 743
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 828-1122 2.92e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 2.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKaeqmhqsfvaETSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKD----------LGEEEQLRVKEKIGELEAEIASLERSIA 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   988 QEKMNLiqksesfanyIDEREKSISELSDqykqekliLLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENR 1067
Cdd:TIGR02169  392 EKLEKL----------KREINELKRELDR--------LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767908145  1068 KNELEQLKEAFAKEHQEFL---TKLAFAEERNQNLMLEL---ETVQQALRSEMTDNQNNSK 1122
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYdlkEEYDRVEKELSKLQRELaeaEAQARASEERVRGGRAVEE 514
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 435-1099 2.97e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 2.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   435 LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKE-NELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   514 QCLNQSQNFAEEMKAKNTSQETMLRDLQEKInqQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLsktek 593
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEY--AELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI----- 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   594 eskallsalelkkkeyEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRE 673
Cdd:TIGR02169  402 ----------------NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   674 NLSVEIRNLHNVLD--SKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQ-LTGQVEDL-----EHKLQL---- 741
Cdd:TIGR02169  466 KYEQELYDLKEEYDrvEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgVHGTVAQLgsvgeRYATAIevaa 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   742 ---LSNEIMDKD----RCYQDLHAE---------------YESLRDLLKSK-------------------------DASL 774
Cdd:TIGR02169  546 gnrLNNVVVEDDavakEAIELLKRRkagratflplnkmrdERRDLSILSEDgvigfavdlvefdpkyepafkyvfgDTLV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   775 VTNEDHQRSLLA-----------FDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKnsaiLQNRVDSLEFSLESQK 843
Cdd:TIGR02169  626 VEDIEAARRLMGkyrmvtlegelFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEG----LKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   844 QMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFvaetSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 923
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL----KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKL 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   924 QAEIQELKKsnHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEngtlkeiNASLNQEKMNLIQKSESFANY 1003
Cdd:TIGR02169  778 EEALNDLEA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE-------KEYLEKEIQELQEQRIDLKEQ 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1004 IDEREKSISELsdqyKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNEctslCENRKNELEQLKEAFAKEHQ 1083
Cdd:TIGR02169  849 IKSIEKEIENL----NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE----LERKIEELEAQIEKKRKRLS 920

                          730
                   ....*....|....*.
gi 767908145  1084 EFLTKLAFAEERNQNL 1099
Cdd:TIGR02169  921 ELKAKLEALEEELSEI 936
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 627-1156 3.28e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 3.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRN---LHNVLDSKSVEVETQKLAYMEL 703
Cdd:TIGR04523   60 DKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNdkeQKNKLEVELNKLEKQKKENKKN 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   704 QQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRS 783
Cdd:TIGR04523  140 IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQ 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   784 LLAFDQQ----------------------PAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLES 841
Cdd:TIGR04523  220 ISELKKQnnqlkdniekkqqeinektteiSNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISD 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   842 ---------QKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSfVAETSQRISKLQEDTSAHQNVVAETLSALENKEKE 912
Cdd:TIGR04523  300 lnnqkeqdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ-ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE 378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   913 -------LQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINAS 985
Cdd:TIGR04523  379 nqsykqeIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKN 458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   986 LNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETgnayEDLSQKYKAAQEKNSKLECLLNECTSLCE 1065
Cdd:TIGR04523  459 LDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEKLESEKK 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1066 NRKNELEQLKEAFAKEHQEfLTKLAFAEE--RNQNLMLELETVQQALRSEMTDNQN---NSKSEAGGLKQEIMTLKEEQN 1140
Cdd:TIGR04523  535 EKESKISDLEDELNKDDFE-LKKENLEKEidEKNKEIEELKQTQKSLKKKQEEKQElidQKEKEKKDLIKEIEEKEKKIS 613

                          570
                   ....*....|....*.
gi 767908145  1141 KMQKEVNDLLQENEQL 1156
Cdd:TIGR04523  614 SLEKELEKAKKENEKL 629
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 420-999 3.30e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 3.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKa 499
Cdd:TIGR04523  107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNI- 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   500 revchlEAELKNIKQCLNQSQNFAEEMKA---KNTSQETMLRDLQEKINQQENSLTLEKLKLA--VADLEKQRDCSQDLL 574
Cdd:TIGR04523  186 ------QKNIDKIKNKLLKLELLLSNLKKkiqKNKSLESQISELKKQNNQLKDNIEKKQQEINekTTEISNTQTQLNQLK 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   575 KKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKtlfscwKSENEKLLTQMESEKENLQSKINHLETCLKTQ 654
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN------NQKEQDWNKELKSELKNQEKKLEEIQNQISQN 333

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   655 QIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLaymelqqkaefSDQKHQKEIENMCLKTSQLTGQVED 734
Cdd:TIGR04523  334 NKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK-----------ENQSYKQEIKNLESQINDLESKIQN 402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   735 LEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASL--VTNEDHQRSLlafdqqpamhhSFANIIGEQGSMPSERS 812
Cdd:TIGR04523  403 QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIkdLTNQDSVKEL-----------IIKNLDNTRESLETQLK 471

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   813 ECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDt 892
Cdd:TIGR04523  472 VLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD- 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   893 sahqnvvaetlsaleNKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEEL 972
Cdd:TIGR04523  551 ---------------DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL 615

                          570       580
                   ....*....|....*....|....*..
gi 767908145   973 TQENGTLKEINASLNQEKMNLIQKSES 999
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKSKKNK 642
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2602-2824 3.35e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.46  E-value: 3.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2602 MDKMSFVEKVNKMTAKETELQREMHEmaQKTAELQEELSGEKNRLAGELQLLLEEIKsskyeveiqtyreKLTSKEECLS 2681
Cdd:PRK05771   56 SEALDKLRSYLPKLNPLREEKKKVSV--KSLEELIKDVEEELEKIEKEIKELEEEIS-------------ELENEIKELE 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2682 SQKLEIDLLK--SSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMK---LLIKSCKQLEEEKEILQK- 2755
Cdd:PRK05771  121 QEIERLEPWGnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGYvyvVVVVLKELSDEVEEELKKl 200

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145 2756 ELSQLQAAQEkqktGTVMD------TKVDELTTEIKELKETLEEKTKE-ADEYLDKYCSLLISHEKLEKAKEMLET 2824
Cdd:PRK05771  201 GFERLELEEE----GTPSElireikEELEEIEKERESLLEELKELAKKyLEELLALYEYLEIELERAEALSKFLKT 272
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1899-2111 3.64e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 3.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1899 DVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTM-------S 1971
Cdd:COG3883    20 AKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaralyrsG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1972 KKTTALDQLsekmkektqeLESHQ-SECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2050
Cdd:COG3883   100 GSVSYLDVL----------LGSESfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767908145 2051 KCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQ 2111
Cdd:COG3883   170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 249-565 3.79e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.20  E-value: 3.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  249 EQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKgQVNKFQELQLQLE----K 324
Cdd:PRK10929  108 EQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERRLQTLGTPNT-PLAQAQLTALQAEsaalK 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  325 AKVELIEKEKVLNKCRDELVRTTAqyDQASTKYTALEQKLKKLTEDLSCQRQ-NAESArcsleqkikekekefqeeLSRQ 403
Cdd:PRK10929  187 ALVDELELAQLSANNRQELARLRS--ELAKKRSQQLDAYLQALRNQLNSQRQrEAERA------------------LEST 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  404 QRsfqtLDQECIQMKARLTQELQQAKNMHNVL--QA-ELDKLTSVKQQLENNLEEFKQKLCR-AEQA--FQASQIKENEL 477
Cdd:PRK10929  247 EL----LAEQSGDLPKSIVAQFKINRELSQALnqQAqRMDLIASQQRQAASQTLQVRQALNTlREQSqwLGVSNALGEAL 322

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  478 RRSME---EMKKennllkshSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKN---TSQETMLRDLQEKInQQE--N 549
Cdd:PRK10929  323 RAQVArlpEMPK--------PQQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQADGqplTAEQNRILDAQLRT-QREllN 393

                         330       340
                  ....*....|....*....|....*
gi 767908145  550 S---------LTLEKLKLAVADLEK 565
Cdd:PRK10929  394 SllsggdtliLELTKLKVANSQLED 418
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2566-2767 3.81e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 3.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2566 EQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELsgeKNR 2645
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL---GER 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2646 LA-----GELQLLLEEIKSSKyevEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLK 2720
Cdd:COG3883    92 ARalyrsGGSVSYLDVLLGSE---SFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEA 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 767908145 2721 YVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQ 2767
Cdd:COG3883   169 AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2036-2198 4.59e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 4.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2036 KLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEA--ALVEKGEFALRLSSTQEE 2113
Cdd:COG1579    11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEveARIKKYEEQLGNVRNNKE 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELqmsEENQELVILDAENSKAEVETLKTQIEE 2193
Cdd:COG1579    91 YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAEL---EEKKAELDEELAELEAELEELEAEREE 167


                  ....*
gi 767908145 2194 MARSL 2198
Cdd:COG1579   168 LAAKI 172
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 2053-2453 4.81e-04

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 45.84  E-value: 4.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2053 ELENQIAQLNKEKELLVKESESLQARLSESD-YEKLNVSKALEAALVEKgefalRLSSTQEEVHQLRRGIEKLRVRIEAD 2131
Cdd:pfam05622   18 ELDQQVSLLQEEKNSLQQENKKLQERLDQLEsGDDSGTPGGKKYLLLQK-----QLEQLQEENFRLETARDDYRIKCEEL 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2132 EKKQLHiaekLKERERENDSLKDKVENLERELQ-MSEENQELVILDAEnskaeVETLKTQIEEMA---RSLKVFE----- 2202
Cdd:pfam05622   93 EKEVLE----LQHRNEELTSLAEEAQALKDEMDiLRESSDKVKKLEAT-----VETYKKKLEDLGdlrRQVKLLEernae 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2203 -----LDL-------VTLRSEKENLTKQIQEKQGQLS-----------ELDKLLSSFKSLLEEKEQAEIQiKEESKTAVE 2259
Cdd:pfam05622  164 ymqrtLQLeeelkkaNALRGQLETYKRQVQELHGKLSeeskkadklefEYKKLEEKLEALQKEKERLIIE-RDTLRETNE 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2260 ML---QNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK--LRARLEADEKKQLCVLQQLKESEHHadll 2334
Cdd:pfam05622  243 ELrcaQLQQAELSQADALLSPSSDPGDNLAAEIMPAEIREKLIRLQHENkmLRLGQEGSYRERLTELQQLLEDANR---- 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2335 kgRVENLERELEIArtNQEHAALEA--ENSKGEVETLKAKIEGMTQSLRGLELDVVTIRsekeNLTNELQKEQERISELE 2412
Cdd:pfam05622  319 --RKNELETQNRLA--NQRILELQQqvEELQKALQEQGSKAEDSSLLKQKLEEHLEKLH----EAQSELQKKKEQIEELE 390

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 767908145  2413 IINSS--------FENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNER 2453
Cdd:pfam05622  391 PKQDSnlaqkideLQEALRKKDEDMKAMEERYKKYVEKAKSVIKTLDPK 439
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2028-2760 5.30e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 5.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2028 KDKTHLQEKLQSLEKDSQALSLTKceleNQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRL 2107
Cdd:TIGR00618  163 KEKKELLMNLFPLDQYTQLALMEF----AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQT 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2108 SSTQEEVHQLRRGIEklrvriEADEKKQLhiAEKLKERERENDSLKDKVENLERELQMSEENQELvildAENSKAeVETL 2187
Cdd:TIGR00618  239 QQSHAYLTQKREAQE------EQLKKQQL--LKQLRARIEELRAQEAVLEETQERINRARKAAPL----AAHIKA-VTQI 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2188 KTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEM-----LQ 2262
Cdd:TIGR00618  306 EQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTqhihtLQ 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2263 NQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQL-------CVLQQLKESEHHADLLK 2335
Cdd:TIGR00618  386 QQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAElcaaaitCTAQCEKLEKIHLQESA 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2336 GRVENLEREL--------EIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKenLTNELQKEQER 2407
Cdd:TIGR00618  466 QSLKEREQQLqtkeqihlQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQR--GEQTYAQLETS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2408 ISELEIINSSFENILQEKEqEKVQMKEKSSTAMEMLQTQLKELNERVaaLHNDQEACKAKEQNLSSQVECLELEKAQLLQ 2487
Cdd:TIGR00618  544 EEDVYHQLTSERKQRASLK-EQMQEIQQSFSILTQCDNRSKEDIPNL--QNITVRLQDLTEKLSEAEDMLACEQHALLRK 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2488 GLDEAKNNYIvlqssvnglIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELrnltveleq 2567
Cdd:TIGR00618  621 LQPEQDLQDV---------RLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAL--------- 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2568 kiQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEElsgekNRLA 2647
Cdd:TIGR00618  683 --QKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQ-----ARTV 755

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2648 GELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKL---EIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2724
Cdd:TIGR00618  756 LKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLreeDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLS 835

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 767908145  2725 LKKENERAQGKMKLLIK---SCKQLEEEKEILQKELSQL 2760
Cdd:TIGR00618  836 RLEEKSATLGEITHQLLkyeECSKQLAQLTQEQAKIIQL 874
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 355-1252 5.84e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 5.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   355 TKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRsfQTLDQECIQMKARLTQELQQAknmhnv 434
Cdd:TIGR00606  182 TRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQ--LESSREIVKSYENELDPLKNR------ 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   435 lQAELDKLTSVKQQLENNLEEFKQ-KLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Cdd:TIGR00606  254 -LKEIEHNLSKIMKLDNEIKALKSrKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLN 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   514 QCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEK 593
Cdd:TIGR00606  333 KERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   594 ESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRE 673
Cdd:TIGR00606  413 LCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEK 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   674 NLSVEIRNLHNV---------------LDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHK 738
Cdd:TIGR00606  493 NSLTETLKKEVKslqnekadldrklrkLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNK 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   739 LQLlsNEIMDKDRcyQDLHAEYESLRDLLKSKdASLVTNEDHQRSLLAF--DQQPAMHHSFANIIGEQgSMPSERSECRL 816
Cdd:TIGR00606  573 KQL--EDWLHSKS--KEINQTRDRLAKLNKEL-ASLEQNKNHINNELESkeEQLSSYEDKLFDVCGSQ-DEESDLERLKE 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   817 EADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEEnlmkaeqmhqsfvaetsqRISKLQEDTSAHQ 896
Cdd:TIGR00606  647 EIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE------------------FISDLQSKLRLAP 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   897 NVVAETLSALENKEKELQLLNDKVETEQAEIQelkksnhLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEn 976
Cdd:TIGR00606  709 DKLKSTESELKKKEKRRDEMLGLAPGRQSIID-------LKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE- 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   977 gtlkEINASLNQEKMNLIQKsesFANYIDEREKSISELSDQYKQEKLILlqrceetgnAYEDLSQKYKAAQEKNSKLECL 1056
Cdd:TIGR00606  781 ----EESAKVCLTDVTIMER---FQMELKDVERKIAQQAAKLQGSDLDR---------TVQQVNQEKQEKQHELDTVVSK 844

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1057 LNECTSLCENRKNELEQLKEAFAKEHQEFLtKLAFAEERNQNLMLELETVQQALRSemtdnqnnskseaggLKQEIMTLK 1136
Cdd:TIGR00606  845 IELNRKLIQDQQEQIQHLKSKTNELKSEKL-QIGTNLQRRQQFEEQLVELSTEVQS---------------LIREIKDAK 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1137 EEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQmdlevkeislDSYNAQLVQLEAM 1216
Cdd:TIGR00606  909 EQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQ----------DGKDDYLKQKETE 978

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 767908145  1217 LRNKELKLQESEKEKECLQHELQTIRGDLETSNLQD 1252
Cdd:TIGR00606  979 LNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQE 1014
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 19-674 5.98e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 5.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    19 KIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRE----NQRLME---ICESLEKTKQKISHELQ 91
Cdd:TIGR04523   34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQikdlNDKLKKnkdKINKLNSDLSKINSEIK 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    92 VKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTpsqyysgsKYEDLKEKY 171
Cdd:TIGR04523  114 NDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELN--------LLEKEKLNI 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   172 NKEVE----ERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTpshlssnsqrtpirrDFSASYFS 247
Cdd:TIGR04523  186 QKNIDkiknKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEIN---------------EKTTEISN 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   248 GEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELE-LRLQGHEKEMKGQV----NKFQELQLQL 322
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNnQKEQDWNKELKSELknqeKKLEEIQNQI 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   323 ---EKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEE 399
Cdd:TIGR04523  331 sqnNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   400 lsrqQRSFQTLDQEciqmKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR 479
Cdd:TIGR04523  411 ----DEQIKKLQQE----KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQ 482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   480 SMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA 559
Cdd:TIGR04523  483 NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   560 VADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFscwKSENEKLltqmESEKEN 639
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKA---KKENEKL----SSIIKN 635

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 767908145   640 LQSKINHLETCLKtqQIKSHEYNERVRTLEMDREN 674
Cdd:TIGR04523  636 IKSKKNKLKQEVK--QIKETIKEIRNKWPEIIKKI 668
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1776-2840 6.46e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 45.81  E-value: 6.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1776 VKETSNENLRLLHVIEDRDRKVESLLNEMKELDS---KLHLQEVQLMTKieaciELEKIVGELKKE-----NSDLSEKLE 1847
Cdd:TIGR01612  684 VKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETatvELHLSNIENKKN-----ELLDIIVEIKKHihgeiNKDLNKILE 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1848 YFSCDHQELLQRVETSEGLNSDLEMHA-----------DKSSREDIGDNVAKVN-DSWKERFLDV---ENELSRIRSEKA 1912
Cdd:TIGR01612  759 DFKNKEKELSNKINDYAKEKDELNKYKskiseiknhynDQINIDNIKDEDAKQNyDKSKEYIKTIsikEDEIFKIINEMK 838

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1913 SIEHEalYLEADLEVVQTEKLCLEKDNE---------NKQKVIVClEEELSVVTSERNQLRGELDTMSKKTTALDQLSEK 1983
Cdd:TIGR01612  839 FMKDD--FLNKVDKFINFENNCKEKIDSeheqfaeltNKIKAEIS-DDKLNDYEKKFNDSKSLINEINKSIEEEYQNINT 915

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1984 MKE-----KTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDK--THLQEKLQSLEKDSQALSLTKCELEN 2056
Cdd:TIGR01612  916 LKKvdeyiKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKfdNTLIDKINELDKAFKDASLNDYEAKN 995

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2057 Q--IAQLNKEKELLVKESES-LQARLSESDYEKLNVSKALEAAL--VEKGEFALRLS--STQEEVHQL-RRGIEKLRVRI 2128
Cdd:TIGR01612  996 NelIKYFNDLKANLGKNKENmLYHQFDEKEKATNDIEQKIEDANknIPNIEIAIHTSiyNIIDEIEKEiGKNIELLNKEI 1075

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2129 EADEKKQL----HIAEKLK-------------ERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQI 2191
Cdd:TIGR01612 1076 LEEAEINItnfnEIKEKLKhynfddfgkeeniKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDL 1155

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2192 EEMARSlKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSsfkslleekeqaEIQIKEESKTAVEmlqnQLKELNea 2271
Cdd:TIGR01612 1156 EDVADK-AISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLN------------EIAEIEKDKTSLE----EVKGIN-- 1216

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2272 vaaLCGDQEIMKATEQSLDppiEEEHQLRNSIEKLRARLEAdekkqlcvLQQLKESEHHADLLKGRVENLERELE---IA 2348
Cdd:TIGR01612 1217 ---LSYGKNLGKLFLEKID---EEKKKSEHMIKAMEAYIED--------LDEIKEKSPEIENEMGIEMDIKAEMEtfnIS 1282

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2349 RTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGlELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQE 2428
Cdd:TIGR01612 1283 HDDDKDHHIISKKHDENISDIREKSLKIIEDFSE-ESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILKLNKIK 1361

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2429 KVQMKEKSSTamemlqTQLKELNERVAALHNDQEACKAKEQNLSSQVECleleKAQLLQGLDEaknnyivlqSSVNGLIQ 2508
Cdd:TIGR01612 1362 KIIDEVKEYT------KEIEENNKNIKDELDKSEKLIKKIKDDINLEEC----KSKIESTLDD---------KDIDECIK 1422

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2509 EVEDGKQKLEKKDEEI-SRLKNQIQDQEQLVSKLSQVE-----GEHQLWKEQNlelrNLTVELEQKIQVLQSKNASLQDT 2582
Cdd:TIGR01612 1423 KIKELKNHILSEESNIdTYFKNADENNENVLLLFKNIEmadnkSQHILKIKKD----NATNDHDFNINELKEHIDKSKGC 1498

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2583 LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTakETELQREMHEMAQKTAELQEELSGEKNRL---AGELQLLLEEIKS 2659
Cdd:TIGR01612 1499 KDEADKNAKAIEKNKELFEQYKKDVTELLNKYS--ALAIKNKFAKTKKDSEIIIKEIKDAHKKFileAEKSEQKIKEIKK 1576

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2660 SKYEVEIQTYREKLTSKEEC---LSSQKLEIDLLKSS--KEELNNSLKATTQILEELKKTKMDNLkyvNQLKKENERAQG 2734
Cdd:TIGR01612 1577 EKFRIEDDAAKNDKSNKAAIdiqLSLENFENKFLKISdiKKKINDCLKETESIEKKISSFSIDSQ---DTELKENGDNLN 1653

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2735 KMKLLIKSCKQLEEEKEILQKELsqlqaaqekqktgtvmdtkvDELTTEIKELKETLEEKTKEAD-EYLDKYCSLLISH- 2812
Cdd:TIGR01612 1654 SLQEFLESLKDQKKNIEDKKKEL--------------------DELDSEIEKIEIDVDQHKKNYEiGIIEKIKEIAIANk 1713

                         1130      1140
                   ....*....|....*....|....*...
gi 767908145  2813 EKLEKAKEMLETQVAHLCSQQSKQDSRG 2840
Cdd:TIGR01612 1714 EEIESIKELIEPTIENLISSFNTNDLEG 1741
mukB PRK04863
chromosome partition protein MukB;
2209-2580 6.48e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 6.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2209 RSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATE-- 2286
Cdd:PRK04863  278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQAdl 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2287 QSLDPPIEEEHQLRNSI----EKLRARLEADEKKQLCVLQQLKESEHHADLLKGRV---ENLERELEIARTNQEHAALEA 2359
Cdd:PRK04863  358 EELEERLEEQNEVVEEAdeqqEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAiqyQQAVQALERAKQLCGLPDLTA 437

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2360 ENSKGEVETLKAKIEGMTQSLRGLE--LDVV-TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVqmkeks 2436
Cdd:PRK04863  438 DNAEDWLEEFQAKEQEATEELLSLEqkLSVAqAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLREQRHL------ 511

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2437 STAMEMLQTQLKELnERVAALHND-----QEACKAKEQNLS--SQVECLELEKAQLLQGLDEAKNNYIVLQSSVngliqe 2509
Cdd:PRK04863  512 AEQLQQLRMRLSEL-EQRLRQQQRaerllAEFCKRLGKNLDdeDELEQLQEELEARLESLSESVSEARERRMAL------ 584

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2510 vedgKQKLEKKDEEISRLKNQ----IQDQEQLvSKLSQVEGEH--------QLWKEQNLELRNLTVE---LEQKIQVLQS 2574
Cdd:PRK04863  585 ----RQQLEQLQARIQRLAARapawLAAQDAL-ARLREQSGEEfedsqdvtEYMQQLLERERELTVErdeLAARKQALDE 659


                  ....*.
gi 767908145 2575 KNASLQ 2580
Cdd:PRK04863  660 EIERLS 665
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 16-567 6.87e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 6.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   16 ALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKES 95
Cdd:COG1196   230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   96 QVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADvslnpcntpqkifttpltpsqyysgSKYEDLKEKYNKEV 175
Cdd:COG1196   310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE-------------------------EELEEAEAELAEAE 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  176 EERKRLEAEVKALQAKKASQTlpqatmnhRDIARHQASSSVFSWQQEKTPSHLSSNSQRtpirrdfsasyfsgeqevtps 255
Cdd:COG1196   365 EALLEAEAELAEAEEELEELA--------EELLEALRAAAELAAQLEELEEAEEALLER--------------------- 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  256 RSTLQIGKRDANSSFFDNSSsphLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKV 335
Cdd:COG1196   416 LERLEEELEELEEALAELEE---EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  336 LNkcRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ----------NAESARCSLEQKIKEKEKEFQEELSRQQR 405
Cdd:COG1196   493 LL--LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLKAAK 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  406 ----SFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSM 481
Cdd:COG1196   571 agraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  482 EEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVA 561
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730


                  ....*.
gi 767908145  562 DLEKQR 567
Cdd:COG1196   731 EAEREE 736
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1910-2453 7.00e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 7.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1910 EKASIEHEALYLEADLEVVQTEKLCLEKDNE--NKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQL------- 1980
Cdd:TIGR00618  254 EQLKKQQLLKQLRARIEELRAQEAVLEETQEriNRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLlmkraah 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1981 ---SEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQ--TLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELE 2055
Cdd:TIGR00618  334 vkqQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQqhTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATID 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2056 NQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRgIEKLRVRIEADEKKQ 2135
Cdd:TIGR00618  414 TRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-KEQIHLQETRKKAVV 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2136 LHIAEKLKEREREndsLKDKVENLERELQMSEENQ------ELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Cdd:TIGR00618  493 LARLLELQEEPCP---LCGSCIHPNPARQDIDNPGpltrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQ 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQL-------------KELNEAVAALC 2276
Cdd:TIGR00618  570 QSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQdlqdvrlhlqqcsQELALKLTALH 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2277 GDQE-------------IMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQL---CVLQQLKESEHH----ADLLKG 2336
Cdd:TIGR00618  650 ALQLtltqervrehalsIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTllrELETHIEEYDREfneiENASSS 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2337 RVENLERELEIARTNQEHA------ALEAENSKGEVETLKAKIEGMT-QSLRGLELDVVTIRSEKENLTNEL-----QKE 2404
Cdd:TIGR00618  730 LGSDLAAREDALNQSLKELmhqartVLKARTEAHFNNNEEVTAALQTgAELSHLAAEIQFFNRLREEDTHLLktleaEIG 809

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 767908145  2405 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEmLQTQLKELNER 2453
Cdd:TIGR00618  810 QEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGE-ITHQLLKYEEC 857
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2467-2661 7.34e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.82  E-value: 7.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKL---SQ 2543
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraLY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2544 VEGEHQLWKEQNLELRNLTvELEQKIQVLQSKNASLQDTLEVLQSSYKNLENEleltkmdKMSFVEKVNKMTAKETELQR 2623
Cdd:COG3883    97 RSGGSVSYLDVLLGSESFS-DFLDRLSALSKIADADADLLEELKADKAELEAK-------KAELEAKLAELEALKAELEA 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 767908145 2624 EMHEMAQKTAELQE---ELSGEKNRLAGELQLLLEEIKSSK 2661
Cdd:COG3883   169 AKAELEAQQAEQEAllaQLSAEEAAAEAQLAELEAELAAAE 209
46 PHA02562
endonuclease subunit; Provisional
 1923-2117 7.64e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 7.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1923 ADLEVVQTEKLCLEKDNENKqkvIVCLEEELSVVTSERNQLRGELdtmSKKTTALDQLSEKMKEKTQELESHQS--ECLH 2000
Cdd:PHA02562  216 ARKQNKYDELVEEAKTIKAE---IEELTDELLNLVMDIEDPSAAL---NKLNTAAAKIKSKIEQFQKVIKMYEKggVCPT 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2001 CIQVAEAEVKEKTELLQTLSSDVSELLKDKTHlQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS 2080
Cdd:PHA02562  290 CTQQISEGPDRITKIKDKLKELQHSLEKLDTA-IDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE 368

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 767908145 2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQL 2117
Cdd:PHA02562  369 ELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHR 405
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2649-2839 7.67e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 7.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2649 ELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKE 2728
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2729 NERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKtgtvmdTKVDELTTEIKELKETLEEKTKEADEYLDKYCSL 2808
Cdd:COG1196   297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELE------EELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                         170       180       190
                  ....*....|....*....|....*....|.
gi 767908145 2809 LISHEKLEKAKEMLETQVAHLCSQQSKQDSR 2839
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQ 401
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2116-2351 7.75e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 7.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2116 QLRRGIEKLRVRIEaDEKKQLHIAE-KLKERERENDSLKDKVENLERELQMSEENQELVILDAE--NSKAEVETLKTQIE 2192
Cdd:COG3206   172 EARKALEFLEEQLP-ELRKELEEAEaALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAElaEAEARLAALRAQLG 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2193 EMARSLKVFELDlvtlrSEKENLTKQIQEKQGQLSELDKLLS----SFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKEL 2268
Cdd:COG3206   251 SGPDALPELLQS-----PVIQQLRAQLAELEAELAELSARYTpnhpDVIALRAQIAALRAQLQQEAQRILASLEAELEAL 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2269 NEAVAalcgdqeimkateqsldppieeehQLRNSIEKLRARLEADEKKQlcvlQQLKEsehhadllkgrvenLERELEIA 2348
Cdd:COG3206   326 QAREA------------------------SLQAQLAQLEARLAELPELE----AELRR--------------LEREVEVA 363


                  ...
gi 767908145 2349 RTN 2351
Cdd:COG3206   364 REL 366
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2127-2275 7.97e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 7.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2127 RIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEM--ARSLKVFELD 2204
Cdd:COG1579    18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnNKEYEALQKE 97

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767908145 2205 LVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL 2275
Cdd:COG1579    98 IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1961-2164 8.30e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 8.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1961 NQLRGELDTMSKKTTALDQLSE---KMKEKTQELEsHQSECL---------HCIQVAEAEVKEKTELLQTLSSDVSELLK 2028
Cdd:COG4913   238 ERAHEALEDAREQIELLEPIRElaeRYAAARERLA-ELEYLRaalrlwfaqRRLELLEAELEELRAELARLEAELERLEA 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2029 DKTHLQEKLQSLEKDSQALSLTKCE-LENQIAQLNKEKELLVKESESLQARLsesdyEKLNVSKALEAALVEkgEFALRL 2107
Cdd:COG4913   317 RLDALREELDELEAQIRGNGGDRLEqLEREIERLERELEERERRRARLEALL-----AALGLPLPASAEEFA--ALRAEA 389

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908145 2108 SSTQEEVHQLRRGIEKLRVRIEADEKKQLhiaEKLKERERENDSLKDKVENLERELQ 2164
Cdd:COG4913   390 AALLEALEEELEALEEALAEAEAALRDLR---RELRELEAEIASLERRKSNIPARLL 443
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2005-2185 8.58e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 8.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2005 AEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSE--- 2081
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErar 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2082 SDYEKLNVSKALEAALVEK--GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENL 2159
Cdd:COG3883    94 ALYRSGGSVSYLDVLLGSEsfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                         170       180
                  ....*....|....*....|....*.
gi 767908145 2160 ERelQMSEENQELVILDAENSKAEVE 2185
Cdd:COG3883   174 EA--QQAEQEALLAQLSAEEAAAEAQ 197
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2160-2493 9.11e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 9.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2160 ERELQMSEENQELVILD---AENSKAEVETLKTQIEEMARSLKVFELDL-----VTLRSEKENLTKQIqekqgqlseLDK 2231
Cdd:COG3206    86 QIEILKSRPVLERVVDKlnlDEDPLGEEASREAAIERLRKNLTVEPVKGsnvieISYTSPDPELAAAV---------ANA 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2232 LLSSFKSLLEEKEQaeiqikEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPiEEEHQLRNSIEKLRARLE 2311
Cdd:COG3206   157 LAEAYLEQNLELRR------EEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLS-EEAKLLLQQLSELESQLA 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2312 AdekkqlcVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALeaensKGEVETLKAKIEGMTQSLRGLELDVVTIR 2391
Cdd:COG3206   230 E-------ARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQL-----RAQLAELEAELAELSARYTPNHPDVIALR 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2392 SEKENLTNELQKEQERIseleiinssfeniLQEKEQEkvqmkeksstaMEMLQTQLKELNERVAALHNDQEACKAKEQ-- 2469
Cdd:COG3206   298 AQIAALRAQLQQEAQRI-------------LASLEAE-----------LEALQAREASLQAQLAQLEARLAELPELEAel 353

                         330       340
                  ....*....|....*....|....*
gi 767908145 2470 -NLSSQVECLELEKAQLLQGLDEAK 2493
Cdd:COG3206   354 rRLEREVEVARELYESLLQRLEEAR 378
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2141-2309 9.47e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 9.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2141 KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE--NLTKQ 2218
Cdd:COG1579    18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeALQKE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2219 IQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEhq 2298
Cdd:COG1579    98 IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE-- 175

                         170
                  ....*....|.
gi 767908145 2299 LRNSIEKLRAR 2309
Cdd:COG1579   176 LLALYERIRKR 186
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 281-990 9.79e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.71  E-value: 9.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   281 DQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKV----------ELIEKEKVLNKCRDELVRTTAQY 350
Cdd:pfam05483   88 EKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLkleeeiqenkDLIKENNATRHLCNLLKETCARS 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   351 DQASTKYTALEQKLKKLTEDLSCQ-----------RQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Cdd:pfam05483  168 AEKTKKYEYEREETRQVYMDLNNNiekmilafeelRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLI 247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499
Cdd:pfam05483  248 QITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTIC 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   500 REVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKlavadlekqrdcsqdlLKKREH 579
Cdd:pfam05483  328 QLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITME----------------LQKKSS 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   580 HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEkenlQSKINHLETCLKTQQIKSH 659
Cdd:pfam05483  392 ELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAR----EKEIHDLEIQLTAIKTSEE 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   660 EYNERVRTLEMDRENlsVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFsdQKHQKEIENMCLKTSQLTGQVEDLEHKL 739
Cdd:pfam05483  468 HYLKEVEDLKTELEK--EKLKNIELTAHCDKLLLENKELTQEASDMTLEL--KKHQEDIINCKKQEERMLKQIENLEEKE 543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   740 QLLSNEImdkdrcyQDLHAEYESLRDLLKSK-DASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEA 818
Cdd:pfam05483  544 MNLRDEL-------ESVREEFIQKGDEVKCKlDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQE 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   819 DQSPKNSAILQN--------RVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETsqriSKLQE 890
Cdd:pfam05483  617 NKALKKKGSAENkqlnayeiKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEA----VKLQK 692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   891 DTSAH-QNVVAETLSALENKEKELqllnDKVETEQAEIQELKKSNHLLEDSLKelQLLSETLSLEKKEMSSIISLNKREI 969
Cdd:pfam05483  693 EIDKRcQHKIAEMVALMEKHKHQY----DKIIEERDSELGLYKNKEQEQSSAK--AALEIELSNIKAELLSLKKQLEIEK 766

                          730       740
                   ....*....|....*....|.
gi 767908145   970 EELTQENGTLKEINASLNQEK 990
Cdd:pfam05483  767 EEKEKLKMEAKENTAILKDKK 787
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1787-2798 1.48e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.40  E-value: 1.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1787 LHVIEDRDRKVESLLNEMKE-----LDSKLHLQEvQLMTKIEACIELEKIVGELKKENSDLSEKLeyfscdhQELLQRVE 1861
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKkhqqlCEEKNALQE-QLQAETELCAEAEEMRARLAARKQELEEIL-------HELESRLE 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1862 TSEGLNSDLEMHADKssredigdnvakvndsWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNEN 1941
Cdd:pfam01576   86 EEEERSQQLQNEKKK----------------MQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSK 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1942 KQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Cdd:pfam01576  150 LSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQA 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2022 DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKg 2101
Cdd:pfam01576  230 QIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL- 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2102 EFALRLSSTQEEVHQlRRGIEKLRVRIEADEKKQLHIAEKLKEREREN---DSLKDKVENLERELQMSEENQELVILDAE 2178
Cdd:pfam01576  309 EDTLDTTAAQQELRS-KREQEVTELKKALEEETRSHEAQLQEMRQKHTqalEELTEQLEQAKRNKANLEKAKQALESENA 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2179 NSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAV 2258
Cdd:pfam01576  388 ELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLE 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2259 EMLQNQLKELNEAVAALCGDQEIMKATEqsldppiEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRV 2338
Cdd:pfam01576  468 SQLQDTQELLQEETRQKLNLSTRLRQLE-------DERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTL 540

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2339 ENLErelEIARTNQEhaaleaenskgEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSF 2418
Cdd:pfam01576  541 EALE---EGKKRLQR-----------ELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKF 606

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2419 ENILQEKEQEKVQMKEKSSTAmemlQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIV 2498
Cdd:pfam01576  607 DQMLAEEKAISARYAEERDRA----EAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHE 682

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2499 LQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKL-SQVEGEHQLWKEQNLE--------LRNLTVELE--- 2566
Cdd:pfam01576  683 LERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALkAQFERDLQARDEQGEEkrrqlvkqVRELEAELEder 762

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2567 -QKIQVLQSKNASLQDTLEV--------------------LQSSYKNLENELELTKMDKMSFV-------EKVNKMTAKE 2618
Cdd:pfam01576  763 kQRAQAVAAKKKLELDLKELeaqidaankgreeavkqlkkLQAQMKDLQRELEEARASRDEILaqskeseKKLKNLEAEL 842

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2619 TELQREM--HEMAQKTA-----ELQEELSG----------EKNRLAGELQLLLEEIKSSKYEVEIQTYR-EKLTSKEECL 2680
Cdd:pfam01576  843 LQLQEDLaaSERARRQAqqerdELADEIASgasgksalqdEKRRLEARIAQLEEELEEEQSNTELLNDRlRKSTLQVEQL 922

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2681 ---------SSQKLEIDllKSSKEELNNSLKATTQILEELKKTKMDN---------LKYVNQLKKENERAQGKMKLLIKS 2742
Cdd:pfam01576  923 ttelaaersTSQKSESA--RQQLERQNKELKAKLQEMEGTVKSKFKSsiaaleakiAQLEEQLEQESRERQAANKLVRRT 1000

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145  2743 CKQLEEEkeILQKELSQLQAAQEKQKtgtvmdtkVDELTTEIKELKETLEEKTKEA 2798
Cdd:pfam01576 1001 EKKLKEV--LLQVEDERRHADQYKDQ--------AEKGNSRMKQLKRQLEEAEEEA 1046
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
828-1172 1.50e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:COG4717   137 LEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLkELQLLSETLSLEkKEMSSIISLNKREIEELTQENGTLKEINASLN 987
Cdd:COG4717   217 EAQEELEELEEELEQLENELEAAALEERLKEARL-LLLIAAALLALL-GLGGSLLSLILTIAGVLFLVLGLLALLFLLLA 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  988 QEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNS-----KLECLLNECTS 1062
Cdd:COG4717   295 REKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEleeelQLEELEQEIAA 374

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1063 LCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQnnsKSEAGGLKQEIMTLKEEQNKM 1142
Cdd:COG4717   375 LLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL---EEELEELEEELEELEEELEEL 451

                         330       340       350
                  ....*....|....*....|....*....|...
gi 767908145 1143 QKEVNDLLQENEQLMK---VMKTKHECQNLESE 1172
Cdd:COG4717   452 REELAELEAELEQLEEdgeLAELLQELEELKAE 484
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2055-2274 1.66e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2055 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEkgefalrLSSTQEEVHQLRRGIEKLRVRIEADEkk 2134
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-------LEALQAEIDKLQAEIAEAEAEIEERR-- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2135 qlhiaEKLKERER----------------ENDSLKDKVENLERELQMSEENQELV------ILDAENSKAEVETLKTQIE 2192
Cdd:COG3883    86 -----EELGERARalyrsggsvsyldvllGSESFSDFLDRLSALSKIADADADLLeelkadKAELEAKKAELEAKLAELE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2193 EMARSLKVFELDLVTLRSEKENLTKQIQEKQGQL-SELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEA 2271
Cdd:COG3883   161 ALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAeAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 240


                  ...
gi 767908145 2272 VAA 2274
Cdd:COG3883   241 AAA 243
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2609-2804 1.76e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2609 EKVNKMTAKETELQREMHEMAQKTAELQEELsgekNRLAGELQLLLEEIKssKYEVEIQTYREKLTSKEECLSSQ----- 2683
Cdd:COG3883    23 KELSELQAELEAAQAELDALQAELEELNEEY----NELQAELEALQAEID--KLQAEIAEAEAEIEERREELGERaraly 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2684 -------KLEIDLLKSSKEELNNSLKATTQILEelkktkmDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKE 2756
Cdd:COG3883    97 rsggsvsYLDVLLGSESFSDFLDRLSALSKIAD-------ADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 767908145 2757 LSQLQAAQEKQKtgtvmdTKVDELTTEIKELKETLEEKTKEADEYLDK 2804
Cdd:COG3883   170 KAELEAQQAEQE------ALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
2014-2271 1.79e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2014 ELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKAL 2093
Cdd:COG4372    24 ILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEEL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2094 EAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELV 2173
Cdd:COG4372   104 ESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQ 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2174 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEE 2253
Cdd:COG4372   184 ALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEEL 263

                         250
                  ....*....|....*...
gi 767908145 2254 SKTAVEMLQNQLKELNEA 2271
Cdd:COG4372   264 ELAILVEKDTEEEELEIA 281
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2661-2794 1.89e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.69  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2661 KYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELK----------KTKMDNLKYVNQLKKENE 2730
Cdd:COG2433   396 EAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLErelsearseeRREIRKDREISRLDREIE 475

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767908145 2731 RaqgkmklLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKV-DELTTE-IKELKETLEEK 2794
Cdd:COG2433   476 R-------LERELEEERERIEELKRKLERLKELWKLEHSGELVPVKVvEKFTKEaIRRLEEEYGLK 534
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2558-2768 2.62e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 2.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2558 LRNLTVELEQKIQVLQSKNASLQDTL---------EVLQSSYKNLEN------ELELTKMDKMSfvEKVNKMTAKETELQ 2622
Cdd:COG4717    14 FRDRTIEFSPGLNVIYGPNEAGKSTLlafiramllERLEKEADELFKpqgrkpELNLKELKELE--EELKEAEEKEEEYA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2623 REMHEMAQKTAELqEELSGEKNRLAGELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSL- 2701
Cdd:COG4717    92 ELQEELEELEEEL-EELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEa 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2702 ---KATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQK 2768
Cdd:COG4717   171 elaELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA 240
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 2543-2766 3.11e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.96  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2543 QVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQ 2622
Cdd:pfam07888   56 QREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELE 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2623 REMHEMAQKTAELQEELSGEKNRLAGELQLLLEEiksskyEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSlk 2702
Cdd:pfam07888  136 EDIKTLTQRVLERETELERMKERAKKAGAQRKEE------EAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQ-- 207

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767908145  2703 atTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2766
Cdd:pfam07888  208 --VLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDR 269
Leu_zip pfam15294
Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 ...
 2720-2826 3.51e-03

Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 (LZTFL1) and Leucine zipper protein 2 (LUZP2).


Pssm-ID: 464620 [Multi-domain]  Cd Length: 276  Bit Score: 42.00  E-value: 3.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2720 KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELK----ETLEEKT 2795
Cdd:pfam15294  133 MEIERLKEENEKLKERLKTLESQATQALDEKSKLEKALKDLQKEQGAKKDVKSNLKEISDLEEKMAALKsdleKTLNAST 212

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 767908145  2796 KEADEYLDKYCS----LLISHEKLEKAKEMLETQV 2826
Cdd:pfam15294  213 ALQKSLEEDLAStkheLLKVQEQLEMAEKELEKKF 247
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 32-195 3.53e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 3.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   32 KEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENqrlmeicESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQI 111
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-------AALERRIAALARRIRALEQELAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  112 EKLEQELKRCKSELERSQQAAQsadvsLNPCNTPQKIFTTPLTPSQYYSGSKY------------EDLKEKYNKEVEERK 179
Cdd:COG4942    93 AELRAELEAQKEELAELLRALY-----RLGRQPPLALLLSPEDFLDAVRRLQYlkylaparreqaEELRADLAELAALRA 167

                         170
                  ....*....|....*.
gi 767908145  180 RLEAEVKALQAKKASQ 195
Cdd:COG4942   168 ELEAERAELEALLAEL 183
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1946-2116 3.93e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 3.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1946 IVCLEEELSVVTSERNQLRGELDTMSKK----TTALDQLSEKMKEKTQELESHQSEclhcIQVAEAEVKEKTELLQTL-- 2019
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAEleelNEEYNELQAELEALQAEIDKLQAE----IAEAEAEIEERREELGERar 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2020 -----------------SSDVSELLKD-------KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESL 2075
Cdd:COG3883    94 alyrsggsvsyldvllgSESFSDFLDRlsalskiADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 767908145 2076 QARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQ 2116
Cdd:COG3883   174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1906-2245 4.04e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.14  E-value: 4.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1906 RIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNEnkqkvivCLEEELSVVTSERNQLRGELdtmsKKTTALD--QLSEK 1983
Cdd:COG5022   811 EYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAE-------VLIQKFGRSLKAKKRFSLLK----KETIYLQsaQRVEL 879

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1984 MKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL--------- 2054
Cdd:COG5022   880 AERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYvklpelnkl 959

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2055 ---ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEAD 2131
Cdd:COG5022   960 hevESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSES 1039

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2132 EKKQlhiaEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE-VETLKTQIEemARSLKVFELDLVTLRS 2210
Cdd:COG5022  1040 TELS----ILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLEsTENLLKTIN--VKDLEVTNRNLVKPAN 1113

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 767908145 2211 EKENLTKQiQEKQGQLSELDKLLSSFKSLLEEKEQ 2245
Cdd:COG5022  1114 VLQFIVAQ-MIKLNLLQEISKFLSQLVNTLEPVFQ 1147
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 828-1054 4.33e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 4.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  828 LQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEqmhqsfvaetsQRISKLQEDTSAHQNVVAETLSALE 907
Cdd:COG1196   258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE-----------QDIARLEERRRELEERLEELEEELA 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  908 NKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKEL-QLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASL 986
Cdd:COG1196   327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAeEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767908145  987 NQEKmNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLE 1054
Cdd:COG1196   407 EAEE-ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
278-463 4.63e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 4.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  278 HLLDQLKAQNQE---LRNKINELE-----LRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQ 349
Cdd:COG4913   252 ELLEPIRELAERyaaARERLAELEylraaLRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQ 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  350 YDQAST-KYTALEQKLKKLTEDLSCQRQNAESARcSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQE---- 424
Cdd:COG4913   332 IRGNGGdRLEQLEREIERLERELEERERRRARLE-ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEAlaea 410

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 767908145  425 ---LQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRA 463
Cdd:COG4913   411 eaaLRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
COG5022 COG5022
Myosin heavy chain [General function prediction only];
2448-2799 4.95e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.76  E-value: 4.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2448 KELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEA---KNNYIVLQSSVNGLI--QEVEDGKQKLEKKDE 2522
Cdd:COG5022   810 KEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSlkaKKRFSLLKKETIYLQsaQRVELAERQLQELKI 889

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2523 EISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELR-NLTVELEQKIQVLQSKNASL-----QDTLEVLQSSYKNLENE 2596
Cdd:COG5022   890 DVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKtELIARLKKLLNNIDLEEGPSieyvkLPELNKLHEVESKLKET 969

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2597 LElTKMDKmsfvekVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKYEVEIQTYREKLTSK 2676
Cdd:COG5022   970 SE-EYEDL------LKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTEL 1042

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2677 EECLSSQKLEIDLLKsSKEELNNSLKATtqileelkKTKMDNLKYVNQLKKENERAQGKMK-LLIKSCKQLEEEKEILQK 2755
Cdd:COG5022  1043 SILKPLQKLKGLLLL-ENNQLQARYKAL--------KLRRENSLLDDKQLYQLESTENLLKtINVKDLEVTNRNLVKPAN 1113

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 767908145 2756 ELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEAD 2799
Cdd:COG5022  1114 VLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELD 1157
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2036-2292 5.13e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2036 KLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSEsdyeklnvskaleaalvekgefalrlssTQEEVH 2115
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEA----------------------------LQAEID 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2116 QLRRGIEKLRVRIEADEkkqlhiaEKLKERER----------------ENDSLKDKVENLERELQMSEENQELvILDAEN 2179
Cdd:COG3883    69 KLQAEIAEAEAEIEERR-------EELGERARalyrsggsvsyldvllGSESFSDFLDRLSALSKIADADADL-LEELKA 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2180 SKAEVETLKTQIEEMARSLkvfELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVE 2259
Cdd:COG3883   141 DKAELEAKKAELEAKLAEL---EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217

                         250       260       270
                  ....*....|....*....|....*....|...
gi 767908145 2260 MLQNQLKELNEAVAALCGDQEIMKATEQSLDPP 2292
Cdd:COG3883   218 AAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAG 250
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 2425-2843 5.43e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.50  E-value: 5.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2425 KEQEKVQMKEKSSTAMEM--LQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSS 2502
Cdd:pfam10174   59 KEQYRVTQEENQHLQLTIqaLQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKT 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2503 VNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQ--------------EQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQK 2568
Cdd:pfam10174  139 LEEMELRIETQKQTLGARDESIKKLLEMLQSKglpkksgeedwertRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRR 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2569 IQVLQ--SKNASLQDTLEV-------LQSSYKNLENELELTKMDKMSFVEKVNKmTAKETELQREMHE-MAQKTAELQEE 2638
Cdd:pfam10174  219 NQLQPdpAKTKALQTVIEMkdtkissLERNIRDLEDEVQMLKTNGLLHTEDREE-EIKQMEVYKSHSKfMKNKIDQLKQE 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2639 LSGEKNRLAGeLQLLLEEI--KSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKM 2716
Cdd:pfam10174  298 LSKKESELLA-LQTKLETLtnQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKS 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2717 DNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQ-AAQEKQKTGTVMDTKVDELTTEIKElKETLEEKT 2795
Cdd:pfam10174  377 TLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKeRVKSLQTDSSNTDTALTTLEEALSE-KERIIERL 455

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 767908145  2796 KEADEYLDKycSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2843
Cdd:pfam10174  456 KEQREREDR--ERLEELESLKKENKDLKEKVSALQPELTEKESSLIDL 501
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2064-2266 5.45e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.54  E-value: 5.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2064 EKELLVKESeslQARLSESDYEKLNVSKALEAALvekgeFALRlsstqEEVHQLRRGIEKLRVRIEADEKKQLHIA---- 2139
Cdd:COG2433   312 KEDLSVEEK---LHLAREYGYDNDHERDALAAAL-----KAYD-----AYKNKFERVEKKVPPDVDRDEVKARVIRglsi 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2140 ----EKLKERERENDSLKDKVENLERELQMSEENQELVILDA--ENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK- 2212
Cdd:COG2433   379 eealEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEqvERLEAEVEELEAELEEKDERIERLERELSEARSEEr 458

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767908145 2213 ----------------ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEI----QIKEESKTAVEMLQNQLK 2266
Cdd:COG2433   459 reirkdreisrldreiERLERELEEERERIEELKRKLERLKELWKLEHSGELvpvkVVEKFTKEAIRRLEEEYG 532
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
925-1247 5.80e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 5.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  925 AEIQELKKSNHL-LEDSLKELQLLSETLSlEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANY 1003
Cdd:PRK03918  189 ENIEELIKEKEKeLEEVLREINEISSELP-ELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1004 IDEREKSISELSDQYKQEKLI----------------LLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLcENR 1067
Cdd:PRK03918  268 IEELKKEIEELEEKVKELKELkekaeeyiklsefyeeYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEEL-KKK 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQ-----------NLMLELETVQQAlRSEMTDNQNNSKSEAGGLKQEIMTLK 1136
Cdd:PRK03918  347 LKELEKRLEELEERHELYEEAKAKKEELERlkkrltgltpeKLEKELEELEKA-KEEIEEEISKITARIGELKKEIKELK 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 1137 EEQNKMQKE------VNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQL 1210
Cdd:PRK03918  426 KAIEELKKAkgkcpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQL 505

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 767908145 1211 VQLEAMLRNKEL-KLQESEKEKECLQHELQTIRGDLET 1247
Cdd:PRK03918  506 KELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKS 543
PRK11281 PRK11281
mechanosensitive channel MscK;
2443-2754 5.80e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 5.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2443 LQTQLKELNERvaalhNDQEAckakEQNLSSQVecleLEKAQLLqgLDEAKNNyivlQSSVNGLIQEVEDGKQKLEKKDE 2522
Cdd:PRK11281   41 VQAQLDALNKQ-----KLLEA----EDKLVQQD----LEQTLAL--LDKIDRQ----KEETEQLKQQLAQAPAKLRQAQA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2523 EISRLKNQIQDQ-EQLVSKLSQVEGEHQLWKEQNlELRNLTVELEQkiqvLQSKNASLQDTLEVLQSS-YKNLENELELT 2600
Cdd:PRK11281  102 ELEALKDDNDEEtRETLSTLSLRQLESRLAQTLD-QLQNAQNDLAE----YNSQLVSLQTQPERAQAAlYANSQRLQQIR 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2601 KMDKMSFVEKVNKMTAKETELQREMH----EMAQKTAELQ-------------EELSGEKNRLAGELQLLLEEIKSSKYE 2663
Cdd:PRK11281  177 NLLKGGKVGGKALRPSQRVLLQAEQAllnaQNDLQRKSLEgntqlqdllqkqrDYLTARIQRLEHQLQLLQEAINSKRLT 256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2664 VEIQTYREKLTSKEeclSSQKLEIDLLKSskeELNNSLKATTQILEELKKTkmdnlkyvNQLKKENERAQGKMKLLIKSC 2743
Cdd:PRK11281  257 LSEKTVQEAQSQDE---AARIQANPLVAQ---ELEINLQLSQRLLKATEKL--------NTLTQQNLRVKNWLDRLTQSE 322

                         330
                  ....*....|.
gi 767908145 2744 KQLEEEKEILQ 2754
Cdd:PRK11281  323 RNIKEQISVLK 333
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2294-2459 6.37e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 6.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2294 EEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAEnskgeVETLKAKI 2373
Cdd:COG1579    31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKE-----IESLKRRI 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2374 EGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEiinSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNER 2453
Cdd:COG1579   106 SDLEDEILELMERIEELEEELAELEAELAELEAELEEKK---AELDEELAELEAELEELEAEREELAAKIPPELLALYER 182


                  ....*.
gi 767908145 2454 VAALHN 2459
Cdd:COG1579   183 IRKRKN 188
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 2511-2793 6.95e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 42.15  E-value: 6.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2511 EDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQV---EGEHQLWKEQNLELRN--LTVELEQKIQVLQSK---------- 2575
Cdd:PLN03229  425 EAVKTPVRELEGEVEKLKEQILKAKESSSKPSELalnEMIEKLKKEIDLEYTEavIAMGLQERLENLREEfskansqdql 504

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2576 -NASLQDTLEVLQS----------SYKNLENELELTKMdkMSFVEKVNKMTAKETELQREMH----------EMAQKTAE 2634
Cdd:PLN03229  505 mHPVLMEKIEKLKDefnkrlsrapNYLSLKYKLDMLNE--FSRAKALSEKKSKAEKLKAEINkkfkevmdrpEIKEKMEA 582

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2635 LQEELSGEKNRLAGEL-QLLLEEIKSSKYEVEIQTyrekltskEECLSSQKLEIDLLKSSKEEL-----NNSLKATTQIL 2708
Cdd:PLN03229  583 LKAEVASSGASSGDELdDDLKEKVEKMKKEIELEL--------AGVLKSMGLEVIGVTKKNKDTaeqtpPPNLQEKIESL 654

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2709 EELKKTKMDNLKYVNQLKkeneraqGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDT-----KVDELTTE 2783
Cdd:PLN03229  655 NEEINKKIERVIRSSDLK-------SKIELLKLEVAKASKTPDVTEKEKIEALEQQIKQKIAEALNSselkeKFEELEAE 727

                         330
                  ....*....|
gi 767908145 2784 IKELKETLEE 2793
Cdd:PLN03229  728 LAAARETAAE 737
PRK12704 PRK12704
phosphodiesterase; Provisional
 44-201 7.07e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 7.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   44 LEAALQKQKQKVENEKTEGTNLKRE-----NQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQEL 118
Cdd:PRK12704   33 IKEAEEEAKRILEEAKKEAEAIKKEalleaKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEEL 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  119 KRCKSELERSQQAAQSADVSLnpcntpQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEER---------KRLEAEVKALQ 189
Cdd:PRK12704  113 EKKEKELEQKQQELEKKEEEL------EELIEEQLQELERISGLTAEEAKEILLEKVEEEarheaavliKEIEEEAKEEA 186

                         170
                  ....*....|..
gi 767908145  190 AKKASQTLPQAT 201
Cdd:PRK12704  187 DKKAKEILAQAI 198
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2473-2706 7.24e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 7.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2473 SQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQlvsklsqvegehqlwk 2552
Cdd:COG3883    16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEA---------------- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2553 eqnlELRNLTVELEQKIQVLQsKNASLQDTLEVLQSSyKNLENELeltkmDKMSFVEKVNKMTAKE-TELQREMHEMAQK 2631
Cdd:COG3883    80 ----EIEERREELGERARALY-RSGGSVSYLDVLLGS-ESFSDFL-----DRLSALSKIADADADLlEELKADKAELEAK 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767908145 2632 TAELQEELSgEKNRLAGELQLLLEEIKSSKyeVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQ 2706
Cdd:COG3883   149 KAELEAKLA-ELEALKAELEAAKAELEAQQ--AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2295-2702 7.30e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.96  E-value: 7.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2295 EEHQLRNSIEKLRArleADEKKQLCVLQQLKESEhhaDLLKGRVENLERELEIARTNQEHAALEAE-NSKGEVETLKAKI 2373
Cdd:PRK10929   24 DEKQITQELEQAKA---AKTPAQAEIVEALQSAL---NWLEERKGSLERAKQYQQVIDNFPKLSAElRQQLNNERDEPRS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2374 EGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISEleiINSSFENILQEKE---------QEKVQMKEKSSTAMEmlQ 2444
Cdd:PRK10929   98 VPPNMSTDALEQEILQVSSQLLEKSRQAQQEQDRARE---ISDSLSQLPQQQTearrqlneiERRLQTLGTPNTPLA--Q 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2445 TQLKELNERVAALhndqeacKAKeqnlssqVECLELE-------------KAQLLQGLDEAKNNYI-VLQSSVNGLIQ-E 2509
Cdd:PRK10929  173 AQLTALQAESAAL-------KAL-------VDELELAqlsannrqelarlRSELAKKRSQQLDAYLqALRNQLNSQRQrE 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2510 VEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ-----------VEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNA- 2577
Cdd:PRK10929  239 AERALESTELLAEQSGDLPKSIVAQFKINRELSQalnqqaqrmdlIASQQRQAASQTLQVRQALNTLREQSQWLGVSNAl 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2578 --SLQDTLEVL--QSSYKNLENELELTKMDKMSFVEKVNKmtaketelQREMHEMAQKTAelqEELSGEKNRLagelqll 2653
Cdd:PRK10929  319 geALRAQVARLpeMPKPQQLDTEMAQLRVQRLRYEDLLNK--------QPQLRQIRQADG---QPLTAEQNRI------- 380

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 767908145 2654 leeiksskYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLK 2702
Cdd:PRK10929  381 --------LDAQLRTQRELLNSLLSGGDTLILELTKLKVANSQLEDALK 421
PRK12705 PRK12705
hypothetical protein; Provisional
 2619-2759 7.84e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 41.62  E-value: 7.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145 2619 TELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELN 2698
Cdd:PRK12705   32 AKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDNLENQLEERE 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767908145 2699 NSLKATTQILEELKKTKMDNLKYVNQLKKENERAQgkmkLLIKSCKQLEEEKEILQKELSQ 2759
Cdd:PRK12705  112 KALSARELELEELEKQLDNELYRVAGLTPEQARKL----LLKLLDAELEEEKAQRVKKIEE 168
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 280-476 7.90e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 7.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Cdd:COG3883    25 LSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSY 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  360 LEQKL--KKLTEDLScqrqnaesaRCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQA 437
Cdd:COG3883   105 LDVLLgsESFSDFLD---------RLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEA 175

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 767908145  438 ELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE 476
Cdd:COG3883   176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1949-2066 8.02e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 8.02e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKtelLQTLSSDVSELLK 2028
Cdd:smart00787  149 LDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKEK---LKKLLQEIMIKVK 225

                            90       100       110
                    ....*....|....*....|....*....|....*...
gi 767908145   2029 DKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKE 2066
Cdd:smart00787  226 KLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLE 263
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 18-588 8.89e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 8.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    18 QKIQELEGQLDKLKKEKQQRQFQLDSLEA-ALQKQKQKVENEKTEGTNL---KRENQRLMEICESLEKTKQKISHELQVK 93
Cdd:pfam12128  301 EKRDELNGELSAADAAVAKDRSELEALEDqHGAFLDADIETAAADQEQLpswQSELENLEERLKALTGKHQDVTAKYNRR 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145    94 ESQVNFQEgqlnsgKKQIEKLEQELKRCKSELERSQQAAQSADVSL-NPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYN 172
Cdd:pfam12128  381 RSKIKEQN------NRDIAGIKDKLAKIREARDRQLAVAEDDLQALeSELREQLEAGKLEFNEEEYRLKSRLGELKLRLN 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   173 K-EVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQAsssVFSWQQEKTPSHLSSNSQRTPIRRDFSASYfsgEQE 251
Cdd:pfam12128  455 QaTATPELLLQLENFDERIERAREEQEAANAEVERLQSELR---QARKRRDQASEALRQASRRLEERQSALDEL---ELQ 528

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   252 VTPSRSTL-------------QIGKRDANSSFFDNSSSPHLLDQLKAQ----------------------NQELRNKINE 296
Cdd:pfam12128  529 LFPQAGTLlhflrkeapdweqSIGKVISPELLHRTDLDPEVWDGSVGGelnlygvkldlkridvpewaasEEELRERLDK 608

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   297 LELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVR---------------TTAQYDQASTKYTALE 361
Cdd:pfam12128  609 AEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRlfdekqsekdkknkaLAERKDSANERLNSLE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   362 QKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSF-QTLDQECIQMKARLTQELQQAKNMHNVLQAELD 440
Cdd:pfam12128  689 AQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLkAAIAARRSGAKAELKALETWYKRDLASLGVDPD 768

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   441 KLTSVKQQLENnleeFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREV----CHLEAELKNIKQCL 516
Cdd:pfam12128  769 VIAKLKREIRT----LERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELqqqlARLIADTKLRRAKL 844

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767908145   517 NQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADlekQRDCSQDLLKKREHHIEQLNDKL 588
Cdd:pfam12128  845 EMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGE---RLAQLEDLKLKRDYLSESVKKYV 913
pepcterm_ChnLen TIGR03007
polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this ...
 2215-2442 9.57e-03

polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this protein family belong to the family of polysaccharide chain length determinant proteins (pfam02706). All are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria, and are found near the epsH homolog that is the putative exosortase gene. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274386 [Multi-domain]  Cd Length: 498  Bit Score: 41.58  E-value: 9.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2215 LTKQIQEKQGQLSELDKLLSSFKSlleEK----EQAEIQIKEESKTAVEMLQNQLKELNEAVAAL------CGDQEIMKA 2284
Cdd:TIGR03007  166 IDEQIKTYEKKLEAAENRLKAFKQ---ENggilPDQEGDYYSEISEAQEELEAARLELNEAIAQRdalkrqLGGEEPVLL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2285 TEQSLDPPieeehQLRNSIEKLRARLEAdekkqlcvlQQLKESEHHADllkgrVENLERELEIARTNQEHAALEAENSKG 2364
Cdd:TIGR03007  243 AGSSVANS-----ELDGRIEALEKQLDA---------LRLRYTDKHPD-----VIATKREIAQLEEQKEEEGSAKNGGPE 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2365 EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEK------VQMKEKSST 2438
Cdd:TIGR03007  304 RGEIANPVYQQLQIELAEAEAEIASLEARVAELTARIERLESLLRTIPEVEAELTQLNRDYEVNKsnyeqlLTRRESAEV 383


                   ....
gi 767908145  2439 AMEM 2442
Cdd:TIGR03007  384 SKQM 387
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 280-564 9.70e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 9.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   280 LDQLKAQNQELRNKINELELRLQGHEKEMkgqvnkfQELQLQLEKAKVELIEKEKVLNKCRDELvrttaqyDQASTKYTA 359
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEI-------EQLEQEEEKLKERLEELEEDLSSLEQEI-------ENVKSELKE 762

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145   440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQS 519
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 767908145   520 QNFAEEMKAKNTSQETMLRDLQEkinQQENSLTLEKLKLAVADLE 564
Cdd:TIGR02169  923 KAKLEALEEELSEIEDPKGEDEE---IPEEELSLEDVQAELQRVE 964
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 1980-2564 9.95e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 41.66  E-value: 9.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  1980 LSEKMKEKTQELEshqsecLHCIQVAEAEVKEKTELLQTLSSDVSELLKDkthLQEKLQSLEKDSQALSltkcelENQIA 2059
Cdd:pfam07111   90 LQQKMRLEAQAME------LDALAVAEKAGQAEAEGLRAALAGAEMVRKN---LEEGSQRELEEIQRLH------QEQLS 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2060 QLNKEKEL----LVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQ 2135
Cdd:pfam07111  155 SLTQAHEEalssLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLRKYVGEQVPPE 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2136 LHIAEKLKERERENDSLKDKVEnlerelqmseenqelvilDAENSKAEVETLKTQIEEMARSLKVfeldlvtlrsEKENL 2215
Cdd:pfam07111  235 VHSQTWELERQELLDTMQHLQE------------------DRADLQATVELLQVRVQSLTHMLAL----------QEEEL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2216 TKQIQEKQGQLSELDKLLSSFKSLLEEKEQA-EIQIKE---ESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDP 2291
Cdd:pfam07111  287 TRKIQPSDSLEPEFPKKCRSLLNRWREKVFAlMVQLKAqdlEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKAA 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2292 PIEEEhqlRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2371
Cdd:pfam07111  367 EVEVE---RMSAKGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVR 443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2372 KIEGMtQSLRGLELDVVTIRSEK-----------ENLTNELQKEQERISELEIINSSFENILQE-----KEQEKVQMKEK 2435
Cdd:pfam07111  444 KVHTI-KGLMARKVALAQLRQEScpppppappvdADLSLELEQLREERNRLDAELQLSAHLIQQevgraREQGEAERQQL 522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908145  2436 SSTAmEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAknnyivLQSSVngliQEVEdgKQ 2515
Cdd:pfam07111  523 SEVA-QQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYGQA------LQEKV----AEVE--TR 589

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 767908145  2516 KLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVE 2564
Cdd:pfam07111  590 LREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDE 638
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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