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Conserved domains on  [gi|767910533|ref|XP_011508322|]
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complement factor H-related protein 5 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 110-326 6.05e-15

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.07  E-value: 6.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 110 GDTVQIICNTGYSLQN-NEKNISCVERGWSTPPICsfTKGECHVPileANVD-AQPKKESYKVGDVLKFSCRKNLIRVGS 187
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQC--IKRRCPSP---RDIDnGQLDIGGVDFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 188 DSVQCyQFG------WSPNFPTCKGQvrSCGPPPQLSNGEvKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTT 261
Cdd:PHA02927 122 SKSYC-ELGstgsmvWNPEAPICESV--KCQSPPSISNGR-HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767910533 262 LPTCveQVKTCGYiPELEYGYVQPSVP-PYQHGVSVEVNCRNEYAMIGNNMITCING-IWT-ELPMCV 326
Cdd:PHA02927 198 PPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGnTWQpELPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 290-507 2.96e-13

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.07  E-value: 2.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 290 YQHGVSVEVNCRNEY--AMIGNNMITCINGIWTELPMCVAthqlKRCKIAGVNIKTLLKLSGKEFNhnSRIRYRCSDIFR 367
Cdd:PHA02927  44 YNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDFG--SSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 368 Y---RHSVCINGK-----WNPEVDCTEKREqfCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRW 439
Cdd:PHA02927 118 LigeSKSYCELGStgsmvWNPEAPICESVK--CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 440 QSLPRCveSTAYCgPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR--NKQWSEPPRCL 507
Cdd:PHA02927 196 SDPPTC--QIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpgNTWQPELPKCV 262
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 110-326 6.05e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.07  E-value: 6.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 110 GDTVQIICNTGYSLQN-NEKNISCVERGWSTPPICsfTKGECHVPileANVD-AQPKKESYKVGDVLKFSCRKNLIRVGS 187
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQC--IKRRCPSP---RDIDnGQLDIGGVDFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 188 DSVQCyQFG------WSPNFPTCKGQvrSCGPPPQLSNGEvKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTT 261
Cdd:PHA02927 122 SKSYC-ELGstgsmvWNPEAPICESV--KCQSPPSISNGR-HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767910533 262 LPTCveQVKTCGYiPELEYGYVQPSVP-PYQHGVSVEVNCRNEYAMIGNNMITCING-IWT-ELPMCV 326
Cdd:PHA02927 198 PPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGnTWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 290-507 2.96e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.07  E-value: 2.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 290 YQHGVSVEVNCRNEY--AMIGNNMITCINGIWTELPMCVAthqlKRCKIAGVNIKTLLKLSGKEFNhnSRIRYRCSDIFR 367
Cdd:PHA02927  44 YNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDFG--SSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 368 Y---RHSVCINGK-----WNPEVDCTEKREqfCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRW 439
Cdd:PHA02927 118 LigeSKSYCELGStgsmvWNPEAPICESVK--CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 440 QSLPRCveSTAYCgPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR--NKQWSEPPRCL 507
Cdd:PHA02927 196 SDPPTC--QIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpgNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 452-506 2.19e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 2.19e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533 452 CGPPPSINNGDTTSfPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 506
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 211-266 3.24e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.85  E-value: 3.24e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767910533 211 CGPPPQLSNGEVKeIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTCV 266
Cdd:cd00033    1 CPPPPVPENGTVT-GSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 452-506 5.43e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 5.43e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533   452 CGPPPSINNGDTTSFPlSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 506
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
452-506 2.04e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.88  E-value: 2.04e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533  452 CGPPPSINNGDTTSfPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 506
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 211-265 2.82e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 2.82e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533   211 CGPPPQLSNGEVKeIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTC 265
Cdd:smart00032   1 CPPPPDIENGTVT-SSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
211-265 1.20e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 1.20e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533  211 CGPPPQLSNGEVkEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTC 265
Cdd:pfam00084   1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 110-326 6.05e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.07  E-value: 6.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 110 GDTVQIICNTGYSLQN-NEKNISCVERGWSTPPICsfTKGECHVPileANVD-AQPKKESYKVGDVLKFSCRKNLIRVGS 187
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQC--IKRRCPSP---RDIDnGQLDIGGVDFGSSITYSCNSGYQLIGE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 188 DSVQCyQFG------WSPNFPTCKGQvrSCGPPPQLSNGEvKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTT 261
Cdd:PHA02927 122 SKSYC-ELGstgsmvWNPEAPICESV--KCQSPPSISNGR-HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767910533 262 LPTCveQVKTCGYiPELEYGYVQPSVP-PYQHGVSVEVNCRNEYAMIGNNMITCING-IWT-ELPMCV 326
Cdd:PHA02927 198 PPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGnTWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 290-507 2.96e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.07  E-value: 2.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 290 YQHGVSVEVNCRNEY--AMIGNNMITCINGIWTELPMCVAthqlKRCKIAGVNIKTLLKLSGKEFNhnSRIRYRCSDIFR 367
Cdd:PHA02927  44 YNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDFG--SSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 368 Y---RHSVCINGK-----WNPEVDCTEKREqfCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRW 439
Cdd:PHA02927 118 LigeSKSYCELGStgsmvWNPEAPICESVK--CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 440 QSLPRCveSTAYCgPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR--NKQWSEPPRCL 507
Cdd:PHA02927 196 SDPPTC--QIVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSpgNTWQPELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 352-554 3.48e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 66.99  E-value: 3.48e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 352 FNHNSRIRYRCSDIFRYR-----HSVCINGKWNPEVDCTEKReqfCPPPPQIPNAQNMTTTVNYqdGEKVAVLCKENYLL 426
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQkmgpiYAKCTGTGWTLFNQCIKRR---CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 427 PEAKEIVCKDGRWQSL------PRCveSTAYCGPPPSINNGDTTSFPlSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQW 500
Cdd:PHA02927 119 IGESKSYCELGSTGSMvwnpeaPIC--ESVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767910533 501 SEPPRCLdpcVVSEENMNKNNIQLKwrNDGKLYAKTGDAVEFQCKFPHKAMISS 554
Cdd:PHA02927 196 SDPPTCQ---IVKCPHPTISNGYLS--SGFKRSYSYNDNVDFKCKYGYKLSGSS 244
PHA02831 PHA02831
EEV host range protein; Provisional
 109-267 2.97e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 64.24  E-value: 2.97e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 109 EGDTVQIICNTGYslqnNEKNISCVERGWSTPPICsFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIR---- 184
Cdd:PHA02831  42 ENENLEYKCNNNF----DKVFVTCNNGSWSTKNMC-IGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNKLEkysi 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 185 VGSDSVQCYQFGWSPNFPTCKgqVRSCgPPPQLSNGEVKEIRKEEYgHNEVVEYDCNPNFIINGPKKIQC-VDGEWT-TL 262
Cdd:PHA02831 117 VGNETVKCINKQWVPKYPVCK--LIRC-KYPALQNGFLNVFEKKFY-YGDIVNFKCKKGFILLGSSVSTCdINSIWYpGI 192


                 ....*
gi 767910533 263 PTCVE 267
Cdd:PHA02831 193 PKCVK 197
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 51-204 4.11e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 63.52  E-value: 4.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533  51 GEVFYYSCE--YNFVSPSKSFWTRITCTEEGWSP-TPKC--LRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSLQN 125
Cdd:PHA02927 105 GSSITYSCNsgYQLIGESKSYCELGSTGSMVWNPeAPICesVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIG 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 126 NEkNISCVERGWSTPPICSFTKgeCHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTC 204
Cdd:PHA02927 185 NS-GVLCSGGEWSDPPTCQIVK--CPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNtWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 452-506 2.19e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 2.19e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533 452 CGPPPSINNGDTTSfPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 506
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 211-266 3.24e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.85  E-value: 3.24e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767910533 211 CGPPPQLSNGEVKeIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTCV 266
Cdd:cd00033    1 CPPPPVPENGTVT-GSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 166-326 3.92e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 58.14  E-value: 3.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 166 ESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG----WSPNFPTCkgQVRSCGPPPQLSNGEVKEiRKEEYGHNEVVEYDCN 241
Cdd:PHA02639  38 EKYEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWSNKAPFC--MLKECNDPPSIINGKIYN-KREMYKVGDEIYYVCN 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 242 PN----FIINGPKKIQCV-DGEWTTLPTCVEQVkTCGYiPELEYGYVQ--PSVPPYQHGVSVEVNCRNEYAMIGNNMITC 314
Cdd:PHA02639 115 EHkgvqYSLVGNEKITCIqDKSWKPDPPICKMI-NCRF-PALQNGYINgiPSNKKFYYKTRVGFSCKSGFDLVGEKYSTC 192

                        170
                 ....*....|....
gi 767910533 315 -INGIW-TELPMCV 326
Cdd:PHA02639 193 nINATWfPSIPTCV 206
PHA02831 PHA02831
EEV host range protein; Provisional
 350-507 1.02e-08

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 56.54  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 350 KEFNHNSRIRYRCSDIFRYRHSVCINGKWNPEVDCTEKREqfCPPPPQIPNAQNMTTTVNYQDGEKVAVLCK----ENYL 425
Cdd:PHA02831  38 KVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKRN--CKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYS 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 426 LPEAKEIVCKDGRWQ------SLPRCvestaycgPPPSINNGDTTSFPLSVYpPGSTVTYRCQSFYKLQGSVTVTCR-NK 498
Cdd:PHA02831 116 IVGNETVKCINKQWVpkypvcKLIRC--------KYPALQNGFLNVFEKKFY-YGDIVNFKCKKGFILLGSSVSTCDiNS 186

                        170
                 ....*....|
gi 767910533 499 QW-SEPPRCL 507
Cdd:PHA02831 187 IWyPGIPKCV 196
PHA02831 PHA02831
EEV host range protein; Provisional
 230-382 1.13e-08

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 56.54  E-value: 1.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 230 YGHNEVVEYDCNPNFiinGPKKIQCVDGEWTTLPTCVEQvKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCR----NEYA 305
Cdd:PHA02831  40 YEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIGK-RNCKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYS 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 306 MIGNNMITCINGIWT-ELPMCvathQLKRCKIAGVNiKTLLKLSGKEFNHNSRIRYRCSDIFRYRHSVC----INGKWNP 380
Cdd:PHA02831 116 IVGNETVKCINKQWVpKYPVC----KLIRCKYPALQ-NGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVstcdINSIWYP 190


                 ..
gi 767910533 381 EV 382
Cdd:PHA02831 191 GI 192
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 150-205 4.29e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.77  E-value: 4.29e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533 150 CHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTCK 205
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGgWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 452-506 5.43e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 5.43e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533   452 CGPPPSINNGDTTSFPlSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 506
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
452-506 2.04e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.88  E-value: 2.04e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533  452 CGPPPSINNGDTTSfPLSVYPPGSTVTYRCQSFYKLQGSVTVTCR-NKQWS-EPPRC 506
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 211-265 2.82e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 2.82e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533   211 CGPPPQLSNGEVKeIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTC 265
Cdd:smart00032   1 CPPPPDIENGTVT-SSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 277-393 5.06e-07

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 51.63  E-value: 5.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 277 ELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCINGIWTELPMCvathqLKRCKIAGVNIKTllkLSGKEFNHNS 356
Cdd:PHA02954 134 QLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYISCTANSWNVIPSC-----QQKCDIPSLSNGL---ISGSTFSIGG 205

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 767910533 357 RIRYRCSDIFRYR---HSVCINGKWNPEVD-CTEKREQFCP 393
Cdd:PHA02954 206 VIHLSCKSGFTLTgspSSTCIDGKWNPVLPiCVRSNEEFDP 246
Sushi pfam00084
Sushi repeat (SCR repeat);
392-445 8.70e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 8.70e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767910533  392 CPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVC-KDGRWQSL-PRC 445
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 150-204 1.03e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 1.03e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767910533   150 CHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTC 204
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGtWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 272-325 1.44e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.60  E-value: 1.44e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767910533   272 CGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCI-NGIWT-ELPMC 325
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 110-266 1.64e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 1.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 110 GDTVQIICNTGYSLQNNEKNISCVERG---WST-PPICSFTkgECHVPILEANVDAQPKKESYKVGDVLKFSCRKN---- 181
Cdd:PHA02639  43 GKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSNkAPFCMLK--ECNDPPSIINGKIYNKREMYKVGDEIYYVCNEHkgvq 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 182 LIRVGSDSVQCYQ-FGWSPNFPTCKgqVRSCgPPPQLSNGEVKEI-RKEEYGHNEVVEYDCNPNFIINGPKKIQC-VDGE 258
Cdd:PHA02639 121 YSLVGNEKITCIQdKSWKPDPPICK--MINC-RFPALQNGYINGIpSNKKFYYKTRVGFSCKSGFDLVGEKYSTCnINAT 197


                 ....*....
gi 767910533 259 W-TTLPTCV 266
Cdd:PHA02639 198 WfPSIPTCV 206
PHA02639 PHA02639
EEV host range protein; Provisional
 211-382 1.70e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 1.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 211 CGPPPQLSNGEVKEIrKEEYGHNEVVEYDCNPNFIINGPKKIQCV----DGEWTT-LPTCVeqVKTCGYIPELEYGYVQP 285
Cdd:PHA02639  22 CDKPDDISNGFITEL-MEKYEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSNkAPFCM--LKECNDPPSIINGKIYN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 286 SVPPYQHGVSVEVNCRN----EYAMIGNNMITCI-NGIWT-ELPMCvathQLKRCKIAGVNIKTLLKL-SGKEFNHNSRI 358
Cdd:PHA02639  99 KREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIqDKSWKpDPPIC----KMINCRFPALQNGYINGIpSNKKFYYKTRV 174

                        170       180
                 ....*....|....*....|....*...
gi 767910533 359 RYRCS---DIFRYRHSVC-INGKWNPEV 382
Cdd:PHA02639 175 GFSCKsgfDLVGEKYSTCnINATWFPSI 202
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 272-326 2.74e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.76  E-value: 2.74e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533 272 CGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCI-NGIWT-ELPMCV 326
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 199-326 9.76e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.86  E-value: 9.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 199 PNFPTCKGQVRSCGPPPQLSNGEVKEiRKEEYGHNEVVEYDCNPN-----FIINGPKKIQC-VDGEWTTLPTCVEQVKtC 272
Cdd:PHA02817  12 CNKVYSLCDLNKCCYPPSIKNGYIYN-KKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICeKDGKWNKEFPVCKIIR-C 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767910533 273 GYiPELEYGYVQ--PSVPPYQHGVSVEVNCRNEYAMIGNNMITC-INGIW-TELPMCV 326
Cdd:PHA02817  90 RF-PALQNGFVNgiPDSKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWiPKVPICS 146
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 392-446 1.10e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 42.84  E-value: 1.10e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533 392 CPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVC-KDGRW-QSLPRCV 446
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWsPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
211-265 1.20e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 1.20e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533  211 CGPPPQLSNGEVkEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTC 265
Cdd:pfam00084   1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 143-275 1.56e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.47  E-value: 1.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 143 CSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLI-----RVGSDSVQCYQFG-WSPNFPTCKgqVRSCgPPPQ 216
Cdd:PHA02817  17 SLCDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRgvrytLVGEKNIICEKDGkWNKEFPVCK--IIRC-RFPA 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767910533 217 LSNGEVKEI-RKEEYGHNEVVEYDCNPNFIINGPKKIQC-VDGEW-TTLPTCVEQVKTCGYI 275
Cdd:PHA02817  94 LQNGFVNGIpDSKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWiPKVPICSRDNITYNKI 155
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 392-445 2.03e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.13  E-value: 2.03e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767910533   392 CPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVC-KDGRW-QSLPRC 445
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWsPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 355-518 4.51e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 45.85  E-value: 4.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 355 NSRIRYRCSDIFRYRHSVCINGK--WNPEVDCTEKREQfcppPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEI 432
Cdd:PHA02954  94 NSTITLICKDETKYFRCEEKNGNtsWNDTVTCPNAECQ----PLQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYI 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 433 VCKDGRWQSLPRCVESTAYcgppPSINNGDTTSFPLSVyppGSTVTYRCQSFYKLQGSVTVTCRNKQWSEpprCLDPCVV 512
Cdd:PHA02954 170 SCTANSWNVIPSCQQKCDI----PSLSNGLISGSTFSI---GGVIHLSCKSGFTLTGSPSSTCIDGKWNP---VLPICVR 239


                 ....*.
gi 767910533 513 SEENMN 518
Cdd:PHA02954 240 SNEEFD 245
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 90-143 7.15e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.83  E-value: 7.15e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533  90 CSFP-FVKNGHSESSGLIHLEGDTVQIICNTGYSLQNNEKnISCVERG-WS-TPPIC 143
Cdd:cd00033    1 CPPPpVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSST-ITCTENGgWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 272-448 2.21e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 40.42  E-value: 2.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 272 CGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCI----NGIWT-ELPMCVathqLKRCKIAGVNIKTLLK 346
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSnKAPFCM----LKECNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767910533 347 LSGKEFNHNSRIRYRCSDIFRYRHSVCINGKwnpeVDCTEKReQFCPPPP-------QIPNAQN-----MTTTVNYQDGE 414
Cdd:PHA02639  98 NKREMYKVGDEIYYVCNEHKGVQYSLVGNEK----ITCIQDK-SWKPDPPickmincRFPALQNgyingIPSNKKFYYKT 172

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 767910533 415 KVAVLCKENYLLPEAKEIVCK-DGRW-QSLPRCVES 448
Cdd:PHA02639 173 RVGFSCKSGFDLVGEKYSTCNiNATWfPSIPTCVRN 208
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 90-143 2.70e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.35  E-value: 2.70e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767910533    90 CSFP-FVKNGHSESSGLIHLEGDTVQIICNTGYSLQNNEkNISCVERG-WS-TPPIC 143
Cdd:smart00032   1 CPPPpDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSS-TITCLENGtWSpPPPTC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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