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Conserved domains on  [gi|767916865|ref|XP_011508981|]
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ankyrin and armadillo repeat-containing protein isoform X5 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
526-696 1.37e-18

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 87.70  E-value: 1.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  526 INVSDEAGYTIFHHAALHNRVSIICQLCNANFKVNQRrfvtFSQGPTPLHLAAQACSLETTVCLLCSKADYTLSEKRGWM 605
Cdd:COG0666    80 INAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNAR----DKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNT 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  606 PIHFAAFYDNVCIIIAlcrkdpsLLEA----EATAENQCTPLLLAATSGALDTIQYLFSIGANWRKTDIKGNNIIHLSVL 681
Cdd:COG0666   156 PLHLAAANGNLEIVKL-------LLEAgadvNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAE 228

                         170
                  ....*....|....*
gi 767916865  682 TFHTEVLKYIIKLNI 696
Cdd:COG0666   229 NGNLEIVKLLLEAGA 243
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
738-982 4.50e-10

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 63.76  E-value: 4.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  738 ILDAGTIPALINLLKSSKIK-LQCKTVGLLSNISTHKSA-VHALVEAGGIPSLINLLVCDEPEVHSRCAVILYDIA--QC 813
Cdd:COG5064   110 VIDAGVVPRFVEFMDEIQRDmLQFEAAWALTNIASGTTQqTKVVVDAGAVPLFIQLLSSTEDDVREQAVWALGNIAgdSE 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  814 ENKDVIAKYNGIPSLINLLNLNIENV--LVNVMNCIRVLCIG-----NENNQRAVREHkgLPYLIRFLSSDSGGEAVIAL 886
Cdd:COG5064   190 GCRDYVLQCGALEPLLGLLLSSAIHIsmLRNATWTLSNLCRGknpppDWSNISQALPI--LAKLIYSRDPEVLVDACWAI 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  887 S--KDSRMHQNQICEGNGIAPlvRLLRISTIAEGTLLS-VIRAVGSICIGvahtsNPVSQQLVVDENAFPVLIQLLrNHP 963
Cdd:COG5064   268 SylSDGPNEKIQAVLDVGIPG--RLVELLSHESAKIQTpALRSVGNIVTG-----SDDQTQVIINCGALKAFRSLL-SSP 339

                         250
                  ....*....|....*....
gi 767916865  964 SPNIKVEVAFSLACIVLGN 982
Cdd:COG5064   340 KENIRKEACWTISNITAGN 358
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
526-696 1.37e-18

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 87.70  E-value: 1.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  526 INVSDEAGYTIFHHAALHNRVSIICQLCNANFKVNQRrfvtFSQGPTPLHLAAQACSLETTVCLLCSKADYTLSEKRGWM 605
Cdd:COG0666    80 INAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNAR----DKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNT 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  606 PIHFAAFYDNVCIIIAlcrkdpsLLEA----EATAENQCTPLLLAATSGALDTIQYLFSIGANWRKTDIKGNNIIHLSVL 681
Cdd:COG0666   156 PLHLAAANGNLEIVKL-------LLEAgadvNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAE 228

                         170
                  ....*....|....*
gi 767916865  682 TFHTEVLKYIIKLNI 696
Cdd:COG0666   229 NGNLEIVKLLLEAGA 243
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
738-982 4.50e-10

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 63.76  E-value: 4.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  738 ILDAGTIPALINLLKSSKIK-LQCKTVGLLSNISTHKSA-VHALVEAGGIPSLINLLVCDEPEVHSRCAVILYDIA--QC 813
Cdd:COG5064   110 VIDAGVVPRFVEFMDEIQRDmLQFEAAWALTNIASGTTQqTKVVVDAGAVPLFIQLLSSTEDDVREQAVWALGNIAgdSE 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  814 ENKDVIAKYNGIPSLINLLNLNIENV--LVNVMNCIRVLCIG-----NENNQRAVREHkgLPYLIRFLSSDSGGEAVIAL 886
Cdd:COG5064   190 GCRDYVLQCGALEPLLGLLLSSAIHIsmLRNATWTLSNLCRGknpppDWSNISQALPI--LAKLIYSRDPEVLVDACWAI 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  887 S--KDSRMHQNQICEGNGIAPlvRLLRISTIAEGTLLS-VIRAVGSICIGvahtsNPVSQQLVVDENAFPVLIQLLrNHP 963
Cdd:COG5064   268 SylSDGPNEKIQAVLDVGIPG--RLVELLSHESAKIQTpALRSVGNIVTG-----SDDQTQVIINCGALKAFRSLL-SSP 339

                         250
                  ....*....|....*....
gi 767916865  964 SPNIKVEVAFSLACIVLGN 982
Cdd:COG5064   340 KENIRKEACWTISNITAGN 358
Ank_2 pfam12796
Ankyrin repeats (3 copies);
574-669 1.82e-09

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 55.89  E-value: 1.82e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865   574 LHLAAQACSLETTVCLLCSKADYTLSEKRGWMPIHFAAFYDNVCIIIALCRKDPSLLEaeataENQCTPLLLAATSGALD 653
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLK-----DNGRTALHYAARSGHLE 75

                           90
                   ....*....|....*.
gi 767916865   654 TIQYLFSIGANWRKTD 669
Cdd:pfam12796   76 IVKLLLEKGADINVKD 91
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 710-992 8.89e-06

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 50.49  E-value: 8.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  710 QCESYKRRMMAVMSLEViclaNDQYWrCILDAGTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVE-AGGIPSL 788
Cdd:PLN03200  461 QQQEYAVALLAILTDEV----DESKW-AITAAGGIPPLVQLLETGSQKAKEDSATVLWNLCCHSEDIRACVEsAGAVPAL 535

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  789 INLLVCDEPEVHSRCAVILYDIAQCENKDVIAKyngipsLINLLNLNIENVLVNVMNCIR-VLCIGNENN--QRAVREHK 865
Cdd:PLN03200  536 LWLLKNGGPKGQEIAAKTLTKLVRTADAATISQ------LTALLLGDLPESKVHVLDVLGhVLSVASLEDlvREGSAAND 609

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  866 GLPYLIRFLSS---DSGGEAVIALSKDSRMHQNqICEGNG----IAPLVRLLRISTIAEGTLLSviRAVGSIcigvahtS 938
Cdd:PLN03200  610 ALRTLIQLLSSskeETQEKAASVLADIFSSRQD-LCESLAtdeiINPCIKLLTNNTEAVATQSA--RALAAL-------S 679

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767916865  939 NPVSQQL---VVDENAFPVLIQLLRNhpSPNIKVEVAFS-LACIVLGNDVLQKDLHEN 992
Cdd:PLN03200  680 RSIKENRkvsYAAEDAIKPLIKLAKS--SSIEVAEQAVCaLANLLSDPEVAAEALAED 735
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 731-771 1.95e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 42.83  E-value: 1.95e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 767916865   731 NDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSNIST 771
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 738-770 1.17e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 40.49  E-value: 1.17e-04
                            10        20        30
                    ....*....|....*....|....*....|...
gi 767916865    738 ILDAGTIPALINLLKSSKIKLQCKTVGLLSNIS 770
Cdd:smart00185    8 VVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 537-664 3.29e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 44.60  E-value: 3.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  537 FHHAALHNRVSIICQLCNANFKVNQrrfVTFSQGPTPLHLAAQACSLETTVCLLCSKADYTLSEKRGWMPIHFAAFYDNV 616
Cdd:PHA02875   72 LHDAVEEGDVKAVEELLDLGKFADD---VFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDI 148

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767916865  617 CIIialcrkdPSLLEAEATAENQ----CTPLLLAATSGALDTIQYLFSIGAN 664
Cdd:PHA02875  149 KGI-------ELLIDHKACLDIEdccgCTPLIIAMAKGDIAICKMLLDSGAN 193
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
526-696 1.37e-18

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 87.70  E-value: 1.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  526 INVSDEAGYTIFHHAALHNRVSIICQLCNANFKVNQRrfvtFSQGPTPLHLAAQACSLETTVCLLCSKADYTLSEKRGWM 605
Cdd:COG0666    80 INAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNAR----DKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNT 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  606 PIHFAAFYDNVCIIIAlcrkdpsLLEA----EATAENQCTPLLLAATSGALDTIQYLFSIGANWRKTDIKGNNIIHLSVL 681
Cdd:COG0666   156 PLHLAAANGNLEIVKL-------LLEAgadvNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAE 228

                         170
                  ....*....|....*
gi 767916865  682 TFHTEVLKYIIKLNI 696
Cdd:COG0666   229 NGNLEIVKLLLEAGA 243
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
526-696 8.48e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 79.61  E-value: 8.48e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  526 INVSDEAGYTIFHHAALHNRVSIICQLCNANFKVNQRRfvtfSQGPTPLHLAAQACSLETTVCLLCSKADYTLSEKRGWM 605
Cdd:COG0666   113 VNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQD----NDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGET 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  606 PIHFAAFYDNVCIIIALCRK--DPslleaEATAENQCTPLLLAATSGALDTIQYLFSIGANWRKTDIKGNNIIHLSVLTF 683
Cdd:COG0666   189 PLHLAAENGHLEIVKLLLEAgaDV-----NAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAG 263

                         170
                  ....*....|...
gi 767916865  684 HTEVLKYIIKLNI 696
Cdd:COG0666   264 AALIVKLLLLALL 276
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
738-982 4.50e-10

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 63.76  E-value: 4.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  738 ILDAGTIPALINLLKSSKIK-LQCKTVGLLSNISTHKSA-VHALVEAGGIPSLINLLVCDEPEVHSRCAVILYDIA--QC 813
Cdd:COG5064   110 VIDAGVVPRFVEFMDEIQRDmLQFEAAWALTNIASGTTQqTKVVVDAGAVPLFIQLLSSTEDDVREQAVWALGNIAgdSE 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  814 ENKDVIAKYNGIPSLINLLNLNIENV--LVNVMNCIRVLCIG-----NENNQRAVREHkgLPYLIRFLSSDSGGEAVIAL 886
Cdd:COG5064   190 GCRDYVLQCGALEPLLGLLLSSAIHIsmLRNATWTLSNLCRGknpppDWSNISQALPI--LAKLIYSRDPEVLVDACWAI 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  887 S--KDSRMHQNQICEGNGIAPlvRLLRISTIAEGTLLS-VIRAVGSICIGvahtsNPVSQQLVVDENAFPVLIQLLrNHP 963
Cdd:COG5064   268 SylSDGPNEKIQAVLDVGIPG--RLVELLSHESAKIQTpALRSVGNIVTG-----SDDQTQVIINCGALKAFRSLL-SSP 339

                         250
                  ....*....|....*....
gi 767916865  964 SPNIKVEVAFSLACIVLGN 982
Cdd:COG5064   340 KENIRKEACWTISNITAGN 358
Ank_2 pfam12796
Ankyrin repeats (3 copies);
574-669 1.82e-09

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 55.89  E-value: 1.82e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865   574 LHLAAQACSLETTVCLLCSKADYTLSEKRGWMPIHFAAFYDNVCIIIALCRKDPSLLEaeataENQCTPLLLAATSGALD 653
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLK-----DNGRTALHYAARSGHLE 75

                           90
                   ....*....|....*.
gi 767916865   654 TIQYLFSIGANWRKTD 669
Cdd:pfam12796   76 IVKLLLEKGADINVKD 91
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 710-992 8.89e-06

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 50.49  E-value: 8.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  710 QCESYKRRMMAVMSLEViclaNDQYWrCILDAGTIPALINLLKSSKIKLQCKTVGLLSNISTHKSAVHALVE-AGGIPSL 788
Cdd:PLN03200  461 QQQEYAVALLAILTDEV----DESKW-AITAAGGIPPLVQLLETGSQKAKEDSATVLWNLCCHSEDIRACVEsAGAVPAL 535

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  789 INLLVCDEPEVHSRCAVILYDIAQCENKDVIAKyngipsLINLLNLNIENVLVNVMNCIR-VLCIGNENN--QRAVREHK 865
Cdd:PLN03200  536 LWLLKNGGPKGQEIAAKTLTKLVRTADAATISQ------LTALLLGDLPESKVHVLDVLGhVLSVASLEDlvREGSAAND 609

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  866 GLPYLIRFLSS---DSGGEAVIALSKDSRMHQNqICEGNG----IAPLVRLLRISTIAEGTLLSviRAVGSIcigvahtS 938
Cdd:PLN03200  610 ALRTLIQLLSSskeETQEKAASVLADIFSSRQD-LCESLAtdeiINPCIKLLTNNTEAVATQSA--RALAAL-------S 679

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767916865  939 NPVSQQL---VVDENAFPVLIQLLRNhpSPNIKVEVAFS-LACIVLGNDVLQKDLHEN 992
Cdd:PLN03200  680 RSIKENRkvsYAAEDAIKPLIKLAKS--SSIEVAEQAVCaLANLLSDPEVAAEALAED 735
Ank_4 pfam13637
Ankyrin repeats (many copies);
641-692 1.65e-05

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 43.42  E-value: 1.65e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 767916865   641 TPLLLAATSGALDTIQYLFSIGANWRKTDIKGNNIIHLSVLTFHTEVLKYII 692
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 731-771 1.95e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 42.83  E-value: 1.95e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 767916865   731 NDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSNIST 771
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
686-848 2.15e-05

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 48.73  E-value: 2.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  686 EVLKYIIKLNIPelpvwKTLVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGL 765
Cdd:COG5064   276 EKIQAVLDVGIP-----GRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVIINCGALKAFRSLLSSPKENIRKEACWT 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  766 LSNIST-HKSAVHALVEAGGIPSLINLLVCDEPEVHSR-CAVILYDIAQCENKDVIAKY---NG-IPSLINLLNLNIENV 839
Cdd:COG5064   351 ISNITAgNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEaCWAISNATSGGLNRPDIIRYlvsQGfIKPLCDLLDVVDNKI 430


                  ....*....
gi 767916865  840 LVNVMNCIR 848
Cdd:COG5064   431 IEVALDAIE 439
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 705-1008 6.84e-05

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 47.40  E-value: 6.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  705 LVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQ---CKTVG----------------- 764
Cdd:PLN03200  493 LVQLLETGSQKAKEDSATVLWNLCCHSEDIRACVESAGAVPALLWLLKNGGPKGQeiaAKTLTklvrtadaatisqltal 572

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  765 LLSNISTHKSAV-------------HALVEAG-----GIPSLINLLVCDEPEVHSRCAVILYDIAQCEN--KDVIAKYNG 824
Cdd:PLN03200  573 LLGDLPESKVHVldvlghvlsvaslEDLVREGsaandALRTLIQLLSSSKEETQEKAASVLADIFSSRQdlCESLATDEI 652

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  825 IPSLINLLNLNIENVLVNVMNCIRVLcignennQRAVREHKGLPYLIRflssdsggEAVIALSKDSRMHQNQICEgNGIA 904
Cdd:PLN03200  653 INPCIKLLTNNTEAVATQSARALAAL-------SRSIKENRKVSYAAE--------DAIKPLIKLAKSSSIEVAE-QAVC 716

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  905 PLVRLLRISTIAEGTLLS-VIRAVGSicigVAHTSNPVSQqlvvdENAFPVLIQLLRNHPSPNI---KVEVAFS-LACIV 979
Cdd:PLN03200  717 ALANLLSDPEVAAEALAEdIILPLTR----VLREGTLEGK-----RNAARALAQLLKHFPVDDVlkdSVQCRGTvLALVD 787

                         330       340
                  ....*....|....*....|....*....
gi 767916865  980 LGNDVlqkDLHENEGFEYADVLYLLHSTE 1008
Cdd:PLN03200  788 LLNST---DLDSSATSEALEALALLARTK 813
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
571-693 9.85e-05

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 45.72  E-value: 9.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  571 PTPLHLAAQACSLETTVCLLCSKADYTLSEKRGWMPIHFAAFYDNVCIIIALCRKDpslLEAEATAENQCTPLLLAATSG 650
Cdd:COG0666    22 ALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAG---ADINAKDDGGNTLLHAAARNG 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 767916865  651 ALDTIQYLFSIGANWRKTDIKGNNIIHLSVLTFHTEVLKYIIK 693
Cdd:COG0666    99 DLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLE 141
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 738-770 1.17e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 40.49  E-value: 1.17e-04
                            10        20        30
                    ....*....|....*....|....*....|...
gi 767916865    738 ILDAGTIPALINLLKSSKIKLQCKTVGLLSNIS 770
Cdd:smart00185    8 VVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 723-830 1.30e-04

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 46.63  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  723 SLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSN-ISTHKSAVHALVEAGGIPSLINLLVC-DEPEVH 800
Cdd:PLN03200  170 ALRNLCGSTDGFWSATLEAGGVDILVKLLSSGNSDAQANAASLLARlMMAFESSISKVLDAGAVKQLLKLLGQgNEVSVR 249

                          90       100       110
                  ....*....|....*....|....*....|..
gi 767916865  801 SRCAVILYDI-AQC-ENKDVIAKYNGIPSLIN 830
Cdd:PLN03200  250 AEAAGALEALsSQSkEAKQAIADAGGIPALIN 281
Ank_2 pfam12796
Ankyrin repeats (3 copies);
643-693 2.36e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 41.25  E-value: 2.36e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 767916865   643 LLLAATSGALDTIQYLFSIGANWRKTDIKGNNIIHLSVLTFHTEVLKYIIK 693
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE 51
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 537-664 3.29e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 44.60  E-value: 3.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  537 FHHAALHNRVSIICQLCNANFKVNQrrfVTFSQGPTPLHLAAQACSLETTVCLLCSKADYTLSEKRGWMPIHFAAFYDNV 616
Cdd:PHA02875   72 LHDAVEEGDVKAVEELLDLGKFADD---VFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDI 148

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767916865  617 CIIialcrkdPSLLEAEATAENQ----CTPLLLAATSGALDTIQYLFSIGAN 664
Cdd:PHA02875  149 KGI-------ELLIDHKACLDIEdccgCTPLIIAMAKGDIAICKMLLDSGAN 193
Ank_4 pfam13637
Ankyrin repeats (many copies);
572-622 3.43e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 39.57  E-value: 3.43e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 767916865   572 TPLHLAAQACSLETTVCLLCSKADYTLSEKRGWMPIHFAAFYDNVCIIIAL 622
Cdd:pfam13637    3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
Ank_2 pfam12796
Ankyrin repeats (3 copies);
526-598 3.97e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 40.87  E-value: 3.97e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767916865   526 INVSDEAGYTIFHHAALHNRVSIICQLCNanfKVNQRRfvtFSQGPTPLHLAAQACSLETTVCLLCSKADYTL 598
Cdd:pfam12796   23 ANLQDKNGRTALHLAAKNGHLEIVKLLLE---HADVNL---KDNGRTALHYAARSGHLEIVKLLLEKGADINV 89
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 521-636 4.16e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 44.57  E-value: 4.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  521 TSSSTINVSDEAGYTIFHHAALHNRvSIICQLCNaNFKVNqrrfVTFSQGPTPLHLAAQ-ACSLETTVCLLCSKADYTLS 599
Cdd:PHA02874  211 DHGNHIMNKCKNGFTPLHNAIIHNR-SAIELLIN-NASIN----DQDIDGSTPLHHAINpPCDIDIIDILLYHKADISIK 284

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 767916865  600 EKRGWMPIHFAAFYDNvciiialcrKDPSLLEAEATA 636
Cdd:PHA02874  285 DNKGENPIDTAFKYIN---------KDPVIKDIIANA 312
HEAT COG1413
HEAT repeat [General function prediction only];
701-811 6.95e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.46  E-value: 6.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767916865  701 VWKTLVEMLQCESYKRRMMAVMSLEVIClandqywrcilDAGTIPALINLLKSSKIKLQCKTVGLLSNISTHKS------ 774
Cdd:COG1413    17 AVPALIAALADEDPDVRAAAARALGRLG-----------DPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAvpalia 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 767916865  775 ------------AVHALVEAGG---IPSLINLLVCDEPEVHSRCAVILYDIA 811
Cdd:COG1413    86 alkdedpevrraAAEALGRLGDpaaVPALLEALKDPDWEVRRAAARALGRLG 137
Ank_5 pfam13857
Ankyrin repeats (many copies);
526-577 7.14e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 36.17  E-value: 7.14e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 767916865   526 INVSDEAGYTIFHHAALHNRVSIICQLCNANFKVNQRRFvtfsQGPTPLHLA 577
Cdd:pfam13857    9 LNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDE----EGLTALDLA 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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