|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
732-1229 |
4.03e-16 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 84.99 E-value: 4.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 732 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 787
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 788 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 864
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 865 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 939
Cdd:PHA03247 2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 940 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 1018
Cdd:PHA03247 2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1019 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1096
Cdd:PHA03247 2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1097 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1176
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294 1177 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1229
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
432-934 |
1.30e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.43 E-value: 1.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 432 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 509
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 510 PAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVP 589
Cdd:PHA03247 2631 PSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 590 KSKPalePATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETE 665
Cdd:PHA03247 2709 EPAP---HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTR 2785
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 666 APSMTIVPTTDIEP-----------VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAP 734
Cdd:PHA03247 2786 PAVASLSESRESLPspwdpadppaaVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GD 2861
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 735 TTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE------ 803
Cdd:PHA03247 2862 VRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqp 2941
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 804 -LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPV 877
Cdd:PHA03247 2942 pLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPP 3020
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294 878 PATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 934
Cdd:PHA03247 3021 PVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATP 3075
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1511-1602 |
1.16e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.74 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1511 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1588
Cdd:cd00063 2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
|
90
....*....|....
gi 767926294 1589 LGEGPVSNTVAFST 1602
Cdd:cd00063 80 GGESPPSESVTVTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1512-1592 |
1.59e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 50.31 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1512 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 1589
Cdd:smart00060 3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 767926294 1590 GEG 1592
Cdd:smart00060 81 GEG 83
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1112-1364 |
1.04e-05 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 50.85 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1112 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1189
Cdd:PRK10263 327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1190 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1269
Cdd:PRK10263 402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1270 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1338
Cdd:PRK10263 474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550
|
250 260 270
....*....|....*....|....*....|..
gi 767926294 1339 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1364
Cdd:PRK10263 551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1512-1595 |
4.59e-05 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 43.56 E-value: 4.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1512 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 1588
Cdd:pfam00041 2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78
|
....*..
gi 767926294 1589 LGEGPVS 1595
Cdd:pfam00041 79 GGEGPPS 85
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1328-1607 |
5.30e-04 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 44.61 E-value: 5.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1328 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1407
Cdd:COG3401 48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1408 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1484
Cdd:COG3401 128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1485 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1563
Cdd:COG3401 208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 767926294 1564 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1607
Cdd:COG3401 283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
123-202 |
6.13e-04 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 40.48 E-value: 6.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041 2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71
|
...
gi 767926294 200 GVK 202
Cdd:pfam00041 72 RVQ 74
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
124-202 |
6.30e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 40.29 E-value: 6.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060 4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72
|
...
gi 767926294 200 GVK 202
Cdd:smart00060 73 RVR 75
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1506-1650 |
6.78e-04 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 44.61 E-value: 6.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1506 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 1583
Cdd:COG3401 324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 1584 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1650
Cdd:COG3401 398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
889-1215 |
2.07e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 42.64 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 889 PEASTTLASKTSQRT-RRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVP 967
Cdd:pfam17823 66 APAPVTLTKGTSAAHlNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 968 QTKlVPSTdlePGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----SPEVPQNKSVSVTGF 1043
Cdd:pfam17823 146 RAA-ACRA---NASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSApatlTPARGISTAATATGH 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1044 EPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESP-KETIAPAKTDYVYPTAKAPLWPEEP 1122
Cdd:pfam17823 222 PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPhARRLSPAKHMPSDTMARNPAAPMGA 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1123 KTEVVESITYVSEPPETTlETSPLPSQSITLPSPDEPQ-----------TEPAPKQTPRAPPKP--KTSPRPRI----PQ 1185
Cdd:pfam17823 302 QAQGPIIQVSTDQPVHNT-AGEPTPSPSNTTLEPNTPKsvastnlavvtTTKAQAKEPSASPVPvlHTSMIPEVeatsPT 380
|
330 340 350
....*....|....*....|....*....|
gi 767926294 1186 TQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 1215
Cdd:pfam17823 381 TQPSPLLPTQGAAGPGILLAPEQVATEATA 410
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
123-202 |
3.01e-03 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 38.63 E-value: 3.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 123 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 200
Cdd:cd00063 3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73
|
..
gi 767926294 201 VK 202
Cdd:cd00063 74 VR 75
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
408-793 |
8.27e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 40.91 E-value: 8.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 408 QPQTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE 487
Cdd:pfam03154 170 QPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 488 RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAprKT 567
Cdd:pfam03154 250 QPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRI--HT 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 568 KRPGRRPRPRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTTASKpsERPKTTHRPDAPQIQPGSKPPKQLlpKPQTTAE 647
Cdd:pfam03154 328 PPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSH--KHPPHLSGPSPFQMNSNLPPPPAL--KPLSSLS 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 648 PDMPPTksvSEPVPFETEAPSMTIVPTTDIEPVTVRTEATVTTLA----PKTSQRTRTRRPRPKHKTTPRPETLQTKldf 723
Cdd:pfam03154 404 THHPPS---AHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAAshppTSGLHQVPSQSPFPQHPFVPGGPPPITP--- 477
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 724 gPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLrtEASGTTAAPKVPQRTHRPHP 793
Cdd:pfam03154 478 -PSGPPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEAL--DEAEEPESPPPPPRSPSPEP 544
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
732-1229 |
4.03e-16 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 84.99 E-value: 4.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 732 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 787
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 788 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 864
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 865 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 939
Cdd:PHA03247 2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 940 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 1018
Cdd:PHA03247 2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1019 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1096
Cdd:PHA03247 2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1097 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1176
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294 1177 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1229
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
589-979 |
2.96e-14 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 78.83 E-value: 2.96e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 589 PKSKPALEPATiqPEPLVPTT--ASKPSERPKTT--HRPDAPQIQ--------PGSKPPKQLLPKPQTTAEPDMPPTKSV 656
Cdd:PHA03247 2553 PPLPPAAPPAA--PDRSVPPPrpAPRPSEPAVTSraRRPDAPPQSarprapvdDRGDPRGPAPPSPLPPDTHAPDPPPPS 2630
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 657 SEPVPFETEAPSMTIVPttdiEPVTVRTEATVTTLA-PKTSQRTRTRRPRPKHKTTPRPETLQTkldfgPITPGTSSA-- 733
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVP----PPERPRDDPAPGRVSrPRRARRLGRAAQASSPPQRPRRRAARP-----TVGSLTSLAdp 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 734 PTTTTKRTRRPHPKPKTTPHPEVPQT--KLVPATILEPVLRTEASGTT--------AAPKVPQRTHRPHPK--PKTTLSP 801
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAarQASPALPAAPAPPAVPAGPAtpggparpARPPTTAGPPAPAPPaaPAAGPPR 2781
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 802 EELQTELVPATIFEPVSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATv 881
Cdd:PHA03247 2782 RLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG- 2860
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 882 lePVTLRPEASTTlASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTlrtetwvTTQAPKTSQRTRRPRPKTKTT 961
Cdd:PHA03247 2861 --DVRRRPPSRSP-AAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPP-------QPQAPPPPQPQPQPPPPPQPQ 2930
|
410 420
....*....|....*....|.
gi 767926294 962 PSPEV---PQTKLVPSTDLEP 979
Cdd:PHA03247 2931 PPPPPpprPQPPLAPTTDPAG 2951
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
432-934 |
1.30e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.43 E-value: 1.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 432 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 509
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 510 PAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVP 589
Cdd:PHA03247 2631 PSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 590 KSKPalePATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETE 665
Cdd:PHA03247 2709 EPAP---HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTR 2785
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 666 APSMTIVPTTDIEP-----------VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAP 734
Cdd:PHA03247 2786 PAVASLSESRESLPspwdpadppaaVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GD 2861
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 735 TTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE------ 803
Cdd:PHA03247 2862 VRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqp 2941
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 804 -LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPV 877
Cdd:PHA03247 2942 pLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPP 3020
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294 878 PATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 934
Cdd:PHA03247 3021 PVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATP 3075
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1511-1602 |
1.16e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.74 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1511 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1588
Cdd:cd00063 2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79
|
90
....*....|....
gi 767926294 1589 LGEGPVSNTVAFST 1602
Cdd:cd00063 80 GGESPPSESVTVTT 93
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
422-754 |
9.15e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 60.72 E-value: 9.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 422 PPKTSRTLE-QPRATLAPSETPFVPQKL-EIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPki 499
Cdd:PHA03247 2701 PPPPPPTPEpAPHALVSATPLPPGPAAArQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAG-- 2778
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 500 skspePTWTTPAPGKTQFISLKPKIPLSPEvthtkPAPEPQTLLPSQSTigpETPGTKPSTTLAPRKTKRPGRRPRPRPR 579
Cdd:PHA03247 2779 -----PPRRLTRPAVASLSESRESLPSPWD-----PADPPAAVLAPAAA---LPPAASPAGPLPPPTSAQPTAPPPPPGP 2845
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 580 PKTTPSPE--VPKSKPALEPATIQPEPLVPTTASKPSER-------PKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDM 650
Cdd:PHA03247 2846 PPPSLPLGgsVAPGGDVRRRPPSRSPAAKPAAPARPPVRrlarpavSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP 2925
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 651 PPTKSVSEPVPFETEAPsmtIVPTTDIEPVtvrteatvttlapktsqrtrtrrprpkhkttPRPETLQTKLDFGPITPGT 730
Cdd:PHA03247 2926 PPQPQPPPPPPPRPQPP---LAPTTDPAGA-------------------------------GEPSGAVPQPWLGALVPGR 2971
|
330 340
....*....|....*....|....
gi 767926294 731 SSAPTTTTKRTRRPHPKPKTTPHP 754
Cdd:PHA03247 2972 VAVPRFRVPQPAPSREAPASSTPP 2995
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
422-797 |
1.46e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 60.34 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 422 PPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK--- 498
Cdd:PHA03247 2608 PRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRrra 2687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 499 ---------ISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPePQTLLPSQSTIGPETPGT-----KPSTTLAP 564
Cdd:PHA03247 2688 arptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPAL-PAAPAPPAVPAGPATPGGparpaRPPTTAGP 2766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 565 rkTKRPGRRPRPRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQT 644
Cdd:PHA03247 2767 --PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG 2844
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 645 TAEPDMPPTKSVSEPVPFETEAPSMTIVPTtdiepVTVRTEATVTTLA-PKTSQRTRTRRPRPKHKTTPR-PETLQTKLD 722
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGDVRRRPPSRSPAAK-----PAAPARPPVRRLArPAVSRSTESFALPPDQPERPPqPQAPPPPQP 2919
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 723 FGPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPAtilePVLRTEASGTTAAPK--VPQ-RTHRPHPKPKT 797
Cdd:PHA03247 2920 QPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ----PWLGALVPGRVAVPRfrVPQpAPSREAPASST 2993
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1512-1592 |
1.59e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 50.31 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1512 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 1589
Cdd:smart00060 3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80
|
...
gi 767926294 1590 GEG 1592
Cdd:smart00060 81 GEG 83
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
655-1254 |
2.99e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 52.39 E-value: 2.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 655 SVSEPVPFETEAPSMTIVPTTDIEPVTvrTEATVTTLAPKTSQRTRtrrprpKHKTTPRPETLQTKLDFGPitpgTSSAP 734
Cdd:PRK10263 315 PITEPVAVAAAATTATQSWAAPVEPVT--QTPPVASVDVPPAQPTV------AWQPVPGPQTGEPVIAPAP----EGYPQ 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 735 TTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIF 814
Cdd:PRK10263 383 QSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTY 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 815 EPVSPIKE--APGTTFVPVTDLEPVTFRTEIPATTlATKTSKRTRPPRPRPKTTPSPQ----APETKPVPATVLEPVTLR 888
Cdd:PRK10263 463 QTEQTYQQpaAQEPLYQQPQPVEQQPVVEPEPVVE-ETKPARPPLYYFEEVEEKRAREreqlAAWYQPIPEPVKEPEPIK 541
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 889 PEASTTLASKTSqrtrrprlrtkttPRPEAPESKPVpTAELKPVTLRTETWVTTQAPKTSQRTR-RPRPKTKTTPSPEVP 967
Cdd:PRK10263 542 SSLKAPSVAAVP-------------PVEAAAAVSPL-ASGVKKATLATGAAATVAAPVFSLANSgGPRPQVKEGIGPQLP 607
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 968 QtklvpstdlepgtlrteaPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----------SPEVPQNKS 1037
Cdd:PRK10263 608 R------------------PKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQynddeidamqQDELARQFA 669
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1038 VSVTGFEPVVHSTDAPGTT--------------FALTELQTLILKPVTSP---SLEMTESQPVSDVLEsvtlstESPKEt 1100
Cdd:PRK10263 670 QTQQQRYGEQYQHDVPVNAedadaaaeaelarqFAQTQQQRYSGEQPAGAnpfSLDDFEFSPMKALLD------DGPHE- 742
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1101 iaPAKTDYVYPTAKaPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQsitlPSPDEPQTEPAPKQTPRAPPKPkTSPR 1180
Cdd:PRK10263 743 --PLFTPIVEPVQQ-PQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQ----PQYQQPQQPVAPQPQYQQPQQP-VAPQ 814
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294 1181 PRIPQTQPvPKVPQRVTAKPKTSPSpevsyttPAPKDVLLpHKPYPEVSQSEPVLQPVT-----FRFEPPKTTIAPLET 1254
Cdd:PRK10263 815 PQYQQPQQ-PVAPQPQYQQPQQPVA-------PQPQDTLL-HPLLMRNGDSRPLHKPTTplpslDLLTPPPSEVEPVDT 884
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1112-1364 |
1.04e-05 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 50.85 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1112 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1189
Cdd:PRK10263 327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1190 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1269
Cdd:PRK10263 402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1270 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1338
Cdd:PRK10263 474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550
|
250 260 270
....*....|....*....|....*....|..
gi 767926294 1339 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1364
Cdd:PRK10263 551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
1069-1338 |
1.83e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 49.69 E-value: 1.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1069 PVTSPSLEMTESQPVSDVLESvtlstESPKETIAPAKTDYVYPTAKaplwPEEPKTEVVESITYVSEPPEttletspLPS 1148
Cdd:PTZ00449 520 PPKAPGDKEGEEGEHEDSKES-----DEPKEGGKPGETKEGEVGKK----PGPAKEHKPSKIPTLSKKPE-------FPK 583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1149 QSitlPSPDEPQtEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA--KPKTSPSPEVSYTTPAPKDVLLPHKPYP 1226
Cdd:PTZ00449 584 DP---KHPKDPE-EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESpkSPKRPPPPQRPSSPERPEGPKIIKSPKP 659
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1227 EVSQSEPvlqpvtfrFEPPKTTiapletrgiPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhr 1306
Cdd:PTZ00449 660 PKSPKPP--------FDPKFKE---------KFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRP-- 720
|
250 260 270
....*....|....*....|....*....|..
gi 767926294 1307 fYTTVRPRTSDKPHIRPvlnrttTRPTRPKPS 1338
Cdd:PTZ00449 721 -LPPKLPRDEEFPFEPI------GDPDAEQPD 745
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1115-1476 |
2.01e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.94 E-value: 2.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1115 APLWPEEPKTEVVESityvsEPPETTLETSPLPSQSitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVP---K 1191
Cdd:PHA03247 2591 APPQSARPRAPVDDR-----GDPRGPAPPSPLPPDT---HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPgrvS 2662
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1192 VPQRVTAK--PKTSPSPEVSYTTPAPKDVLLP---------------HKPYPEVSQSEPVLQPVTFRFEPPKTTIAPLeT 1254
Cdd:PHA03247 2663 RPRRARRLgrAAQASSPPQRPRRRAARPTVGSltsladpppppptpePAPHALVSATPLPPGPAAARQASPALPAAPA-P 2741
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1255 RGIPFIPMISPSPSQEELQTTLEETDQST--QEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPVLNRTTTRP 1332
Cdd:PHA03247 2742 PAVPAGPATPGGPARPARPPTTAGPPAPAppAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1333 TRPKPSGMPSGNGVGTGVKQAPRPSGADRNV--SVDSTHPTKKPGTRRPplppRPTHPRRKPLPPNNVTGKPGSAGIISS 1410
Cdd:PHA03247 2822 ASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggSVAPGGDVRRRPPSRS----PAAKPAAPARPPVRRLARPAVSRSTES 2897
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767926294 1411 GPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVR 1476
Cdd:PHA03247 2898 FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1512-1595 |
4.59e-05 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 43.56 E-value: 4.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1512 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 1588
Cdd:pfam00041 2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78
|
....*..
gi 767926294 1589 LGEGPVS 1595
Cdd:pfam00041 79 GGEGPPS 85
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
946-1342 |
6.09e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 48.15 E-value: 6.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 946 KTSQRTRRPRPKTKTTPSPEVPQTKLVPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPK 1025
Cdd:PTZ00449 528 EGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPT 607
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1026 TTSSPEVPQNKSVSVTGFEPvvHSTDAPgttfaltelqtlilKPVTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAK 1105
Cdd:PTZ00449 608 RPKSPKLPELLDIPKSPKRP--ESPKSP--------------KRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1106 TDYVYPT-AKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSP----- 1179
Cdd:PTZ00449 672 KEKFYDDyLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDiefft 751
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1180 -----RPRIPQTQPVPKVPQRVTAKPKTspsPEVSYTTPAPKDVL----LPHKPYPEVSQSEPVLQPVTFRFEPPKTTIA 1250
Cdd:PTZ00449 752 ppeeeRTFFHETPADTPLPDILAEEFKE---EDIHAETGEPDEAMkrpdSPSEHEDKPPGDHPSLPKKRHRLDGLALSTT 828
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1251 PLETRgiPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELA-----------KTTQAPHRFYTTVRPRTSDKP 1319
Cdd:PTZ00449 829 DLESD--AGRIAKDASGKIVKLKRSKSFDDLTTVEEAEEMGAEARKIVvdddgteaddeDTHPPEEKHKSEVRRRRPPKK 906
|
410 420
....*....|....*....|...
gi 767926294 1320 HIRPVLNRTTTRPTRPKPSGMPS 1342
Cdd:PTZ00449 907 PSKPKKPSKPKKPKKPDSAFIPS 929
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
1138-1232 |
8.37e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 47.50 E-value: 8.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1138 ETTLETSPLPSQ-SITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 1216
Cdd:PRK14950 357 EALLVPVPAPQPaKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAI 436
|
90
....*....|....*.
gi 767926294 1217 DVLLPHKPYPEVSQSE 1232
Cdd:PRK14950 437 PVDEKPKYTPPAPPKE 452
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1092-1426 |
4.78e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.16 E-value: 4.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1092 LSTESPKETIAPAKTDYVYPTAKAPLWPE-EPKTEVV--ESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQT 1168
Cdd:PHA03307 44 VSDSAELAAVTVVAGAAACDRFEPPTGPPpGPGTEAPanESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPP 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1169 PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTFRFEPPKTT 1248
Cdd:PHA03307 124 ASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAAS 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1249 IAPLETRGIPFIPMISPSPS---QEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVR------PRTSDKP 1319
Cdd:PHA03307 204 PRPPRRSSPISASASSPAPApgrSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWeasgwnGPSSRPG 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1320 HIRPvlnRTTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 1399
Cdd:PHA03307 284 PASS---SSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPA 360
|
330 340
....*....|....*....|....*..
gi 767926294 1400 GKPGSAGIISSGPITTPPLRSTPRPTG 1426
Cdd:PHA03307 361 DPSSPRKRPRPSRAPSSPAASAGRPTR 387
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1328-1607 |
5.30e-04 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 44.61 E-value: 5.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1328 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1407
Cdd:COG3401 48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1408 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1484
Cdd:COG3401 128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1485 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1563
Cdd:COG3401 208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 767926294 1564 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1607
Cdd:COG3401 283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1039-1292 |
5.97e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 45.08 E-value: 5.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1039 SVTgfEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESPkeTIAPAKTDYV-YPTAKAPL 1117
Cdd:PRK10263 315 PIT--EPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEP--VIAPAPEGYPqQSQYAQPA 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1118 WP-----EEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPK-----PKTSPRPRIPQTQ 1187
Cdd:PRK10263 391 VQyneplQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQqstfaPQSTYQTEQTYQQ 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1188 PVPK-----VPQRVTAKPKTSPSPEVSYTTPAPKDVL----LPHKPYPEVSQSEPVLQPVTFRFEPPKTTIAPLETRGIP 1258
Cdd:PRK10263 471 PAAQeplyqQPQPVEQQPVVEPEPVVEETKPARPPLYyfeeVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVA 550
|
250 260 270
....*....|....*....|....*....|....
gi 767926294 1259 FIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 1292
Cdd:PRK10263 551 AVPPVEAAAAVSPLASGVKKATLATGAAATVAAP 584
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
123-202 |
6.13e-04 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 40.48 E-value: 6.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041 2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71
|
...
gi 767926294 200 GVK 202
Cdd:pfam00041 72 RVQ 74
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
124-202 |
6.30e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 40.29 E-value: 6.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060 4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72
|
...
gi 767926294 200 GVK 202
Cdd:smart00060 73 RVR 75
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1506-1650 |
6.78e-04 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 44.61 E-value: 6.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1506 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 1583
Cdd:COG3401 324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 1584 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1650
Cdd:COG3401 398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
1113-1216 |
7.96e-04 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 43.07 E-value: 7.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1113 AKAPLWP---EEPKTEVVESITYV--SEPPETTLE-----TSPLPSQSITLPSPDEPQTEPAPKqtPRAPPKPKtsPRPR 1182
Cdd:PRK11633 39 AAIPLVPkpgDRDEPDMMPAATQAlpTQPPEGAAEavragDAAAPSLDPATVAPPNTPVEPEPA--PVEPPKPK--PVEK 114
|
90 100 110
....*....|....*....|....*....|....
gi 767926294 1183 iPQTQPVPKVPQRVTAKPKTSPSPEVSyTTPAPK 1216
Cdd:PRK11633 115 -PKPKPKPQQKVEAPPAPKPEPKPVVE-EKAAPT 146
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
593-661 |
1.31e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 43.64 E-value: 1.31e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294 593 PALEPATIQPEPLVPTtASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVP 661
Cdd:PRK14950 362 PVPAPQPAKPTAAAPS-PVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAP 429
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
611-982 |
1.50e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 43.52 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 611 SKPSERPKTTHRPDAPQIQPGSKPPKqllpkPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVTvrTEATVTT 690
Cdd:PTZ00449 537 SKESDEPKEGGKPGETKEGEVGKKPG-----PAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRS--AQRPTRP 609
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 691 LAPKTSQRTRTRRPRPKHKTTPRPETlqtkldfgPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEV-PQTK-LVPATILE 768
Cdd:PTZ00449 610 KSPKLPELLDIPKSPKRPESPKSPKR--------PPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFdPKFKeKFYDDYLD 681
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 769 PVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVP------ATIFEPV-SPIKEAPGTTFVPVTDLEPVTFRT 841
Cdd:PTZ00449 682 AAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPklprdeEFPFEPIgDPDAEQPDDIEFFTPPEEERTFFH 761
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 842 EIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPvpatvLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTPRpEAPES 921
Cdd:PTZ00449 762 ETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRP-----DSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDL-ESDAG 835
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 922 KPVPTAELKPVTLR-----------------------------------TETWVTTQAPKTSQRTRRPRPKTKTTPSPEV 966
Cdd:PTZ00449 836 RIAKDASGKIVKLKrsksfddlttveeaeemgaearkivvdddgteaddEDTHPPEEKHKSEVRRRRPPKKPSKPKKPSK 915
|
410
....*....|....*.
gi 767926294 967 PQTKLVPSTDLEPGTL 982
Cdd:PTZ00449 916 PKKPKKPDSAFIPSII 931
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
889-1215 |
2.07e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 42.64 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 889 PEASTTLASKTSQRT-RRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVP 967
Cdd:pfam17823 66 APAPVTLTKGTSAAHlNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 968 QTKlVPSTdlePGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----SPEVPQNKSVSVTGF 1043
Cdd:pfam17823 146 RAA-ACRA---NASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSApatlTPARGISTAATATGH 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1044 EPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESP-KETIAPAKTDYVYPTAKAPLWPEEP 1122
Cdd:pfam17823 222 PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPhARRLSPAKHMPSDTMARNPAAPMGA 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1123 KTEVVESITYVSEPPETTlETSPLPSQSITLPSPDEPQ-----------TEPAPKQTPRAPPKP--KTSPRPRI----PQ 1185
Cdd:pfam17823 302 QAQGPIIQVSTDQPVHNT-AGEPTPSPSNTTLEPNTPKsvastnlavvtTTKAQAKEPSASPVPvlHTSMIPEVeatsPT 380
|
330 340 350
....*....|....*....|....*....|
gi 767926294 1186 TQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 1215
Cdd:pfam17823 381 TQPSPLLPTQGAAGPGILLAPEQVATEATA 410
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
875-1192 |
2.24e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 42.75 E-value: 2.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 875 KPVPATVLEP-----VTLRPEASTTLAS----KTSQRTRRPRLRTKTT--PRPEAPESKPVPTAELKPvtlrtETWVTTQ 943
Cdd:PTZ00449 560 KPGPAKEHKPskiptLSKKPEFPKDPKHpkdpEEPKKPKRPRSAQRPTrpKSPKLPELLDIPKSPKRP-----ESPKSPK 634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 944 APKTSQRTRRPR----PKT-KTTPSPEVPQTKLVPS------TDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAP 1012
Cdd:PTZ00449 635 RPPPPQRPSSPErpegPKIiKSPKPPKSPKPPFDPKfkekfyDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1013 KTQRTRRPRPRPKTTSSPEVPQNksvsvtgfEPVVHSTDaPGTTFALTELQTLILKpvtspslEMTESQPVSDVL----- 1087
Cdd:PTZ00449 715 FTTPRPLPPKLPRDEEFPFEPIG--------DPDAEQPD-DIEFFTPPEEERTFFH-------ETPADTPLPDILaeefk 778
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1088 -ESVTLSTESPKETIAPAKTDYVYPTAKAPLWPEEPK-----------------------------------TEVVESIT 1131
Cdd:PTZ00449 779 eEDIHAETGEPDEAMKRPDSPSEHEDKPPGDHPSLPKkrhrldglalsttdlesdagriakdasgkivklkrSKSFDDLT 858
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767926294 1132 YVSEPPETTLETSPLPSQSITLPSPDEpQTEPA------------PKQTPRAPPKPKTSPRPRIPQTQPVPKV 1192
Cdd:PTZ00449 859 TVEEAEEMGAEARKIVVDDDGTEADDE-DTHPPeekhksevrrrrPPKKPSKPKKPSKPKKPKKPDSAFIPSI 930
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
844-1012 |
2.24e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.94 E-value: 2.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 844 PATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEA-----STTLASKTSQRTRRPRLRTKTTPRPEA 918
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAaparrSPAPEALAAARQASARGPGGAPAPAPA 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 919 PESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPS-PEVPQTKLVPS-TDLEPGTLRTEAPKTMVVTTVL 996
Cdd:PRK12323 454 PAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPwEELPPEFASPApAQPDAAPAGWVAESIPDPATAD 533
|
170
....*....|....*.
gi 767926294 997 EPDTFRTKFPETTLAP 1012
Cdd:PRK12323 534 PDDAFETLAPAPAAAP 549
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
123-202 |
3.01e-03 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 38.63 E-value: 3.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 123 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 200
Cdd:cd00063 3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73
|
..
gi 767926294 201 VK 202
Cdd:cd00063 74 VR 75
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
1136-1213 |
3.02e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 42.46 E-value: 3.02e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 1136 PPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTP 1213
Cdd:PRK14971 391 QPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLGP 468
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1057-1267 |
3.20e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.17 E-value: 3.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1057 FALTELQTLILKPVTSPSlemtESQPVSDVLESVTLSTE--SPKETIAPAKTDYVYPTAKAPLwPEEPKTEVVESITYVS 1134
Cdd:PRK12323 353 FTMTLLRMLAFRPGQSGG----GAGPATAAAAPVAQPAPaaAAPAAAAPAPAAPPAAPAAAPA-AAAAARAVAAAPARRS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1135 EPPEttletsplPSQSITLPSPDEPQTEPAPkqTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA 1214
Cdd:PRK12323 428 PAPE--------ALAAARQASARGPGGAPAP--APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP 497
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 1215 PKDVLLPHKPYPEVSQSEPVLQPV---------------TFRFEPPKTTIAPLETRGIPFIPMISPSP 1267
Cdd:PRK12323 498 PWEELPPEFASPAPAQPDAAPAGWvaesipdpatadpddAFETLAPAPAAAPAPRAAAATEPVVAPRP 565
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1143-1317 |
5.26e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 41.56 E-value: 5.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1143 TSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQrVTAKPKTSPSPEVSYTTPAPKDVLLPH 1222
Cdd:PRK10811 848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPV-VVAEPQPEEVVVVETTHPEVIAAPVTE 926
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1223 KPYPEVSQSEPVLQPVTFRFEP---------PKTTIAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPR 1293
Cdd:PRK10811 927 QPQVITESDVAVAQEVAEHAEPvvepqdetaDIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQV 1006
|
170 180 190
....*....|....*....|....*....|.
gi 767926294 1294 TTELAKT-------TQAPHRFYTTVRPRTSD 1317
Cdd:PRK10811 1007 PEATVEHnhatapmTRAPAPEYVPEAPRHSD 1037
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
1157-1237 |
5.38e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 41.47 E-value: 5.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1157 DEPQTEPAPKQTPRAPPKPKTSPRP-RIPQTQPVPKVPQRVTAKPKTSPSPEVSYT----TPAPKDVLLPHKPYPEVSQS 1231
Cdd:PRK14954 374 VRNDGGVAPSPAGSPDVKKKAPEPDlPQPDRHPGPAKPEAPGARPAELPSPASAPTpeqqPPVARSAPLPPSPQASAPRN 453
|
....*.
gi 767926294 1232 EPVLQP 1237
Cdd:PRK14954 454 VASGKP 459
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
519-963 |
5.75e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.68 E-value: 5.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 519 SLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPALEP- 597
Cdd:pfam03154 143 STSPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTq 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 598 ATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTksvsePVPFETEAPSMtivpttdi 677
Cdd:pfam03154 223 STAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPM-----PHSLQTGPSHM-------- 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 678 ePVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETlqtkldfgpiTPGTSSAPTTTTKRTRRPHPKPKTTPHPEVP 757
Cdd:pfam03154 290 -QHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHT----------PPSQSQLQSQQPPREQPLPPAPLSMPHIKPP 358
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 758 QtklvpatilepvlrteasgTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSPIK-EAPGTTFVPVTDLEP 836
Cdd:pfam03154 359 P-------------------TTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLStHHPPSAHPPPLQLMP 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 837 VTFRTEIPATT--LATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTlRPEASTTLASKTSQRTRRPRLRTKTTP 914
Cdd:pfam03154 420 QSQQLPPPPAQppVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGG-PPPITPPSGPPTSTSSAMPGIQPPSSA 498
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 767926294 915 RPEAPESKP-VPTAELKPVTLRTETWVTTQAPKT---SQRTRRPRPKTKTTPS 963
Cdd:pfam03154 499 SVSSSGPVPaAVSCPLPPVQIKEEALDEAEEPESpppPPRSPSPEPTVVNTPS 551
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
522-748 |
7.30e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.01 E-value: 7.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 522 PKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRktkrpgrrprprprpKTTPSPEVPKSKPALEPATIQ 601
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAAR---------------AVAAAPARRSPAPEALAAARQ 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 602 PEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVT 681
Cdd:PRK12323 439 ASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAP 518
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294 682 VRTEAtvttlapktsqrtrtrrprpkhKTTPRPETLQTKLDFGPITPGTSSAPTTTTKRTRRPHPKP 748
Cdd:PRK12323 519 AGWVA----------------------ESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAP 563
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
536-975 |
7.42e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 41.06 E-value: 7.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 536 APEPQTLLPSQSTIGPETPGTK---PSTTLAPRKTKRPGRRPRPRPRPKTTpSPEVPKSKPALEPATIQPEPLVPTTASK 612
Cdd:pfam05109 424 APESTTTSPTLNTTGFAAPNTTtglPSSTHVPTNLTAPASTGPTVSTADVT-SPTPAGTTSGASPVTPSPSPRDNGTESK 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 613 PSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEP--DMPPTKSVSEPVPFETEAPSMTIVPTTDiepvtvrteATVTT 690
Cdd:pfam05109 503 APDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTlgKTSPTSAVTTPTPNATSPTPAVTTPTPN---------ATIPT 573
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 691 LApKTSqrtrtrrprpkhkttprpetlqtkldfgPITPGTSSAPTTTTKRTRRPHPKPKTTPHPevpqtklVPATILEPV 770
Cdd:pfam05109 574 LG-KTS----------------------------PTSAVTTPTPNATSPTVGETSPQANTTNHT-------LGGTSSTPV 617
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 771 LRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSpikEAPGTTFVPVTDLEPVTFRTEIPATTLAT 850
Cdd:pfam05109 618 VTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTS---HMPLLTSAHPTGGENITQVTPASTSTHHV 694
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 851 KTSkRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTK------------TTPRPEA 918
Cdd:pfam05109 695 STS-SPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTggkansttggkhTTGHGAR 773
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294 919 PESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVPQTKLVPST 975
Cdd:pfam05109 774 TSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPPVTTAQATVPVPPT 830
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
408-793 |
8.27e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 40.91 E-value: 8.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 408 QPQTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE 487
Cdd:pfam03154 170 QPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 488 RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAprKT 567
Cdd:pfam03154 250 QPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRI--HT 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 568 KRPGRRPRPRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTTASKpsERPKTTHRPDAPQIQPGSKPPKQLlpKPQTTAE 647
Cdd:pfam03154 328 PPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSH--KHPPHLSGPSPFQMNSNLPPPPAL--KPLSSLS 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 648 PDMPPTksvSEPVPFETEAPSMTIVPTTDIEPVTVRTEATVTTLA----PKTSQRTRTRRPRPKHKTTPRPETLQTKldf 723
Cdd:pfam03154 404 THHPPS---AHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAAshppTSGLHQVPSQSPFPQHPFVPGGPPPITP--- 477
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 724 gPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLrtEASGTTAAPKVPQRTHRPHP 793
Cdd:pfam03154 478 -PSGPPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEAL--DEAEEPESPPPPPRSPSPEP 544
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
646-1218 |
9.17e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 40.84 E-value: 9.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 646 AEPDMPptksvSEPVPFETEAPSMtivPTTDIEPVT-VRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDFG 724
Cdd:PRK10263 337 VEPVTQ-----TPPVASVDVPPAQ---PTVAWQPVPgPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYY 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 725 PITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPqtklvpatILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEEL 804
Cdd:PRK10263 409 APAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQP--------VAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQ 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 805 QTELVPATIFEPVsPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATktskrTRPPRPRPKTTPSPQAPETKPVPATVLEP 884
Cdd:PRK10263 481 PQPVEQQPVVEPE-PVVEETKPARPPLYYFEEVEEKRAREREQLAA-----WYQPIPEPVKEPEPIKSSLKAPSVAAVPP 554
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 885 VTLRPeASTTLASKTSQRTrrprLRTKTTPRPEAPESKPVPTAELKPvtlRTETWVTTQAPKtSQRTRRPRPKTKTTPSP 964
Cdd:PRK10263 555 VEAAA-AVSPLASGVKKAT----LATGAAATVAAPVFSLANSGGPRP---QVKEGIGPQLPR-PKRIRVPTRRELASYGI 625
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 965 EVPQTKLVPSTDLEPGTLRTEAPKTMVVTTV--LEPDTFRTKFPETTLAP--KTQRTRRPRPRPKTTSSPEVPQNKSVSV 1040
Cdd:PRK10263 626 KLPSQRAAEEKAREAQRNQYDSGDQYNDDEIdaMQQDELARQFAQTQQQRygEQYQHDVPVNAEDADAAAEAELARQFAQ 705
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1041 TGFEPVVHSTDAPGTTFALTELQtlilkpvTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAktdyvyPTAKAPLWPE 1120
Cdd:PRK10263 706 TQQQRYSGEQPAGANPFSLDDFE-------FSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQ------QQYQQPQQPV 772
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1121 EPKTEVVESITYVSEPPETTLETSPLPSQsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 1200
Cdd:PRK10263 773 APQPQYQQPQQPVAPQPQYQQPQQPVAPQ----PQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHP 848
|
570 580 590
....*....|....*....|....*....|.
gi 767926294 1201 -------------KTSPSPEVSYTTPAPKDV 1218
Cdd:PRK10263 849 llmrngdsrplhkPTTPLPSLDLLTPPPSEV 879
|
|
| |
