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Conserved domains on  [gi|767947344|ref|XP_011514313|]
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autism susceptibility gene 2 protein isoform X2 [Homo sapiens]

Protein Classification

fibrosin/Auts2 domain-containing protein( domain architecture ID 10633998)

fibrosin/Auts2 domain-containing protein similar to human fibrosin-1-like protein, also called autism susceptibility candidate 2 (AUTS2)-like protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Auts2 pfam15336
Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family ...
 651-863 2.41e-83

Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family of eukaryotic proteins associated both with a susceptibility to autism and with influencing the number of corpora lutea produced by breeding sows.


:

Pssm-ID: 464656  Cd Length: 217  Bit Score: 271.33  E-value: 2.41e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   651 KPGKWCAMHVHIAWQIYHHQQKVKkQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTP 730
Cdd:pfam15336    1 KPGKWCAMHVRIAWQIYHHQQKVK-QMQLDPHKLDVGLKLELLSRPPGPGVFGGFPYPHDLARPATLFSATGAAHPSATP 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   731 FGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFP 810
Cdd:pfam15336   80 FGPSPPHGSFLSPASHLDPFSRPSTFGGLGALSSGAFGGLGSPSLTANSVFGHKEGPPLQGFSSPHDPWNRLHRTPPSFP 159

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767947344   811 TPPPWLKPGELERSASAAAHDRDRDVDKRD----SSVSKDDKERESVEK-RHSSHPSP 863
Cdd:pfam15336  160 TPPPWPKPGDAERSSSLESHERERDRERERekrdSSVIKDEKDRDSLDKnRHSSRSSP 217
PAT1 super family cl37801
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 300-437 2.48e-09

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


The actual alignment was detected with superfamily member pfam09770:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 61.98  E-value: 2.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPlstQPPQGPPEAQLQ-PAPQPQVQRPPRPQSPTQLLHQNLPPV 378
Cdd:pfam09770  219 AQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQ---HPGQGHPVTILQrPQSPQPDPAQPSIQPQAQQFHQQPPPV 295

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   379 QAHPSaQSLSQPlsaynsSSLSLNSLSSRSSTPAKTQPAPPHISHH-PSASPFPLSLPNH 437
Cdd:pfam09770  296 PVQPT-QILQNP------NRLSAARVGYPQNPQPGVQPAPAHQAHRqQGSFGRQAPIITH 348
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 271-645 8.26e-07

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.79  E-value: 8.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  271 ISGLErsQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPqtepqlrAPSPDPDLVQRTEAPPQPPPLSTQP-----PQGP 345
Cdd:PHA03247 2537 IRGLE--ELASDDAGDPPPPLPPAAPPAAPDRSVPPPRP-------APRPSEPAVTSRARRPDAPPQSARPrapvdDRGD 2607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  346 PEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQpAPPHISHHP 425
Cdd:PHA03247 2608 PRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQAS-SPPQRPRRR 2686

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  426 SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA--GHPAGSTYSEQDILRQELNTRFLA 503
Cdd:PHA03247 2687 AARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAppAVPAGPATPGGPARPARPPTTAGP 2766

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  504 SQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMVRTPGrnfdkyPTKVDPfyrh 583
Cdd:PHA03247 2767 PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPP------PTSAQP---- 2836

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767947344  584 slfhSYPPAVSGIPPMIPPTGPFGSLQGAF--QPKTSNPIDVAARPGTVPHTLLQKD--PRLTDPF 645
Cdd:PHA03247 2837 ----TAPPPPPGPPPPSLPLGGSVAPGGDVrrRPPSRSPAAKPAAPARPPVRRLARPavSRSTESF 2898
PTZ00121 super family cl31754
MAEBL; Provisional
 845-1008 6.55e-04

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 6.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  845 KDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHL-P 923
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKkA 1440

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  924 EKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKgEPAYENPKKSSEVKVKEERKEDHDLPPEAP 1003
Cdd:PTZ00121 1441 EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAK-KKAEEAKKKADEAKKAAEAKKKADEAKKAE 1519


                  ....*
gi 767947344 1004 QTHRA 1008
Cdd:PTZ00121 1520 EAKKA 1524
 
Name Accession Description Interval E-value
Auts2 pfam15336
Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family ...
 651-863 2.41e-83

Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family of eukaryotic proteins associated both with a susceptibility to autism and with influencing the number of corpora lutea produced by breeding sows.


Pssm-ID: 464656  Cd Length: 217  Bit Score: 271.33  E-value: 2.41e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   651 KPGKWCAMHVHIAWQIYHHQQKVKkQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTP 730
Cdd:pfam15336    1 KPGKWCAMHVRIAWQIYHHQQKVK-QMQLDPHKLDVGLKLELLSRPPGPGVFGGFPYPHDLARPATLFSATGAAHPSATP 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   731 FGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFP 810
Cdd:pfam15336   80 FGPSPPHGSFLSPASHLDPFSRPSTFGGLGALSSGAFGGLGSPSLTANSVFGHKEGPPLQGFSSPHDPWNRLHRTPPSFP 159

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767947344   811 TPPPWLKPGELERSASAAAHDRDRDVDKRD----SSVSKDDKERESVEK-RHSSHPSP 863
Cdd:pfam15336  160 TPPPWPKPGDAERSSSLESHERERDRERERekrdSSVIKDEKDRDSLDKnRHSSRSSP 217
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 300-437 2.48e-09

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 61.98  E-value: 2.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPlstQPPQGPPEAQLQ-PAPQPQVQRPPRPQSPTQLLHQNLPPV 378
Cdd:pfam09770  219 AQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQ---HPGQGHPVTILQrPQSPQPDPAQPSIQPQAQQFHQQPPPV 295

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   379 QAHPSaQSLSQPlsaynsSSLSLNSLSSRSSTPAKTQPAPPHISHH-PSASPFPLSLPNH 437
Cdd:pfam09770  296 PVQPT-QILQNP------NRLSAARVGYPQNPQPGVQPAPAHQAHRqQGSFGRQAPIITH 348
PHA03247 PHA03247
large tegument protein UL36; Provisional
 298-455 6.18e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.64  E-value: 6.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  298 PCPQVAQPIPQPQTEPQLRAPSPdpdlvqrteAPPQPPPLSTQPPQgpPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPP 377
Cdd:PHA03247 2882 PVRRLARPAVSRSTESFALPPDQ---------PERPPQPQAPPPPQ--PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPA 2950

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  378 VQAHPSAQSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLH--------SFTPTLQP 449
Cdd:PHA03247 2951 GAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHeetdpppvSLKQTLWP 3030


                  ....*.
gi 767947344  450 PAHSHH 455
Cdd:PHA03247 3031 PDDTED 3036
PHA03247 PHA03247
large tegument protein UL36; Provisional
 271-645 8.26e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.79  E-value: 8.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  271 ISGLErsQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPqtepqlrAPSPDPDLVQRTEAPPQPPPLSTQP-----PQGP 345
Cdd:PHA03247 2537 IRGLE--ELASDDAGDPPPPLPPAAPPAAPDRSVPPPRP-------APRPSEPAVTSRARRPDAPPQSARPrapvdDRGD 2607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  346 PEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQpAPPHISHHP 425
Cdd:PHA03247 2608 PRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQAS-SPPQRPRRR 2686

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  426 SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA--GHPAGSTYSEQDILRQELNTRFLA 503
Cdd:PHA03247 2687 AARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAppAVPAGPATPGGPARPARPPTTAGP 2766

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  504 SQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMVRTPGrnfdkyPTKVDPfyrh 583
Cdd:PHA03247 2767 PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPP------PTSAQP---- 2836

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767947344  584 slfhSYPPAVSGIPPMIPPTGPFGSLQGAF--QPKTSNPIDVAARPGTVPHTLLQKD--PRLTDPF 645
Cdd:PHA03247 2837 ----TAPPPPPGPPPPSLPLGGSVAPGGDVrrRPPSRSPAAKPAAPARPPVRRLARPavSRSTESF 2898
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 298-394 2.02e-04

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 45.57  E-value: 2.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEA-PPQPPPLSTQPPQGPPEAQlQPAPQPQVQRPPR-----PQSPTQLL 371
Cdd:TIGR01628  383 RQLPMGSPMGGAMGQPPYYGQGPQQQFNGQPLGwPRMSMMPTPMGPGGPLRPN-GLAPMNAVRAPSRnaqnaAQKPPMQP 461

                           90       100
                   ....*....|....*....|...
gi 767947344   372 HQNLPPVQAHPSAQSLSQPLSAY 394
Cdd:TIGR01628  462 VMYPPNYQSLPLSQDLPQPQSTA 484
PTZ00121 PTZ00121
MAEBL; Provisional
 845-1008 6.55e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 6.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  845 KDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHL-P 923
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKkA 1440

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  924 EKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKgEPAYENPKKSSEVKVKEERKEDHDLPPEAP 1003
Cdd:PTZ00121 1441 EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAK-KKAEEAKKKADEAKKAAEAKKKADEAKKAE 1519


                  ....*
gi 767947344 1004 QTHRA 1008
Cdd:PTZ00121 1520 EAKKA 1524
 
Name Accession Description Interval E-value
Auts2 pfam15336
Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family ...
 651-863 2.41e-83

Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family of eukaryotic proteins associated both with a susceptibility to autism and with influencing the number of corpora lutea produced by breeding sows.


Pssm-ID: 464656  Cd Length: 217  Bit Score: 271.33  E-value: 2.41e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   651 KPGKWCAMHVHIAWQIYHHQQKVKkQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTP 730
Cdd:pfam15336    1 KPGKWCAMHVRIAWQIYHHQQKVK-QMQLDPHKLDVGLKLELLSRPPGPGVFGGFPYPHDLARPATLFSATGAAHPSATP 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   731 FGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFP 810
Cdd:pfam15336   80 FGPSPPHGSFLSPASHLDPFSRPSTFGGLGALSSGAFGGLGSPSLTANSVFGHKEGPPLQGFSSPHDPWNRLHRTPPSFP 159

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 767947344   811 TPPPWLKPGELERSASAAAHDRDRDVDKRD----SSVSKDDKERESVEK-RHSSHPSP 863
Cdd:pfam15336  160 TPPPWPKPGDAERSSSLESHERERDRERERekrdSSVIKDEKDRDSLDKnRHSSRSSP 217
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 300-437 2.48e-09

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 61.98  E-value: 2.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPlstQPPQGPPEAQLQ-PAPQPQVQRPPRPQSPTQLLHQNLPPV 378
Cdd:pfam09770  219 AQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQ---HPGQGHPVTILQrPQSPQPDPAQPSIQPQAQQFHQQPPPV 295

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   379 QAHPSaQSLSQPlsaynsSSLSLNSLSSRSSTPAKTQPAPPHISHH-PSASPFPLSLPNH 437
Cdd:pfam09770  296 PVQPT-QILQNP------NRLSAARVGYPQNPQPGVQPAPAHQAHRqQGSFGRQAPIITH 348
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 298-483 1.81e-08

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 58.89  E-value: 1.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   298 PCPQV-AQPIPQPQT----------EPQLRAPSPDPdlvqrteaPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQS 366
Cdd:pfam09770  175 PAPQPaAQPASLPAPsrkmmsleevEAAMRAQAKKP--------AQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQP 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   367 PTQLLHQNLPPVQAHPsAQSLSQPLSAynssslslnslSSRSSTPAKTQPAPPHISHHPSASPFPLSL---PNHSPLHSF 443
Cdd:pfam09770  247 QQQPQQPQQHPGQGHP-VTILQRPQSP-----------QPDPAQPSIQPQAQQFHQQPPPVPVQPTQIlqnPNRLSAARV 314

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 767947344   444 tPTLQPPAHSHHPNmfaPPTALPPPPPLTSGSLQVAGHPA 483
Cdd:pfam09770  315 -GYPQNPQPGVQPA---PAHQAHRQQGSFGRQAPIITHPQ 350
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 257-454 5.44e-08

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 57.47  E-value: 5.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   257 PEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFE--PVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPdlvQRTEAPPQP 334
Cdd:pfam03154  134 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQILQtqPPVLQAQSGAASPPSPPPPGTTQAATAGPTP---SAPSVPPQG 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   335 PPLSTQPPQGP-----PEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAhpSAQSLSQPlsaynssslslNSLSSRSS 409
Cdd:pfam03154  211 SPATSQPPNQTqstaaPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQV--SPQPLPQP-----------SLHGQMPP 277

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 767947344   410 TPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSH 454
Cdd:pfam03154  278 MPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQ 322
PHA03247 PHA03247
large tegument protein UL36; Provisional
 298-455 6.18e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.64  E-value: 6.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  298 PCPQVAQPIPQPQTEPQLRAPSPdpdlvqrteAPPQPPPLSTQPPQgpPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPP 377
Cdd:PHA03247 2882 PVRRLARPAVSRSTESFALPPDQ---------PERPPQPQAPPPPQ--PQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPA 2950

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  378 VQAHPSAQSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLH--------SFTPTLQP 449
Cdd:PHA03247 2951 GAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHeetdpppvSLKQTLWP 3030


                  ....*.
gi 767947344  450 PAHSHH 455
Cdd:PHA03247 3031 PDDTED 3036
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 287-391 6.88e-08

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 57.40  E-value: 6.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  287 EPIFEPVVLKDPCP-----------QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQgppeaqlQPAPQ 355
Cdd:PRK10263  742 EPLFTPIVEPVQQPqqpvapqqqyqQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQ-------PVAPQ 814

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 767947344  356 PQVQRPPRPQSPTQLLHQNLPPVQAHPSaQSLSQPL 391
Cdd:PRK10263  815 PQYQQPQQPVAPQPQYQQPQQPVAPQPQ-DTLLHPL 849
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 298-490 3.83e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 54.66  E-value: 3.83e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   298 PCPQVAQPIPQPQTEPQ--------LRAPSPDPDL----------VQRTEAPPQPPPLSTQPPQGPP-----------EA 348
Cdd:pfam09770  122 SLPQYQYASQQSQQPSKpvrtgyekYKEPEPIPDLqvdaslwgvaPKKAAAPAPAPQPAAQPASLPApsrkmmsleevEA 201

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   349 QL-----QPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSsslslnslssrsstPAKTQPAPPHISH 423
Cdd:pfam09770  202 AMraqakKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQ--------------QHPGQGHPVTILQ 267

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767947344   424 HPSASPFPLSLPNHSPLHSFTPTLQPPAHSH------HPNMFAPPTALPPPPPLTsGSLQVAGHPAGSTYSEQ 490
Cdd:pfam09770  268 RPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQptqilqNPNRLSAARVGYPQNPQP-GVQPAPAHQAHRQQGSF 339
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 287-456 6.09e-07

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 54.32  E-value: 6.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  287 EPIFEPVVLKDPCPQVAQPIPQPqTEPQLRAPSpdpdlVQRTEAPPQPPPLSTQPPQGP--PEAQLQPAPQ--PQVQRPP 362
Cdd:PRK10263  314 APITEPVAVAAAATTATQSWAAP-VEPVTQTPP-----VASVDVPPAQPTVAWQPVPGPqtGEPVIAPAPEgyPQQSQYA 387

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  363 RPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHS 442
Cdd:PRK10263  388 QPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQT 467

                         170
                  ....*....|....*
gi 767947344  443 FT-PTLQPPAHSHHP 456
Cdd:PRK10263  468 YQqPAAQEPLYQQPQ 482
PHA03247 PHA03247
large tegument protein UL36; Provisional
 271-645 8.26e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.79  E-value: 8.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  271 ISGLErsQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPqtepqlrAPSPDPDLVQRTEAPPQPPPLSTQP-----PQGP 345
Cdd:PHA03247 2537 IRGLE--ELASDDAGDPPPPLPPAAPPAAPDRSVPPPRP-------APRPSEPAVTSRARRPDAPPQSARPrapvdDRGD 2607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  346 PEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQpAPPHISHHP 425
Cdd:PHA03247 2608 PRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQAS-SPPQRPRRR 2686

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  426 SASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVA--GHPAGSTYSEQDILRQELNTRFLA 503
Cdd:PHA03247 2687 AARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAppAVPAGPATPGGPARPARPPTTAGP 2766

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  504 SQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMVRTPGrnfdkyPTKVDPfyrh 583
Cdd:PHA03247 2767 PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPP------PTSAQP---- 2836

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767947344  584 slfhSYPPAVSGIPPMIPPTGPFGSLQGAF--QPKTSNPIDVAARPGTVPHTLLQKD--PRLTDPF 645
Cdd:PHA03247 2837 ----TAPPPPPGPPPPSLPLGGSVAPGGDVrrRPPSRSPAAKPAAPARPPVRRLARPavSRSTESF 2898
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 303-419 9.82e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 53.33  E-value: 9.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  303 AQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLL--HQNLPPVQA 380
Cdd:PRK07994  362 AAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQraQGATKAKKS 441

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 767947344  381 HPSAQSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQPAPP 419
Cdd:PRK07994  442 EPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYR 480
PHA03247 PHA03247
large tegument protein UL36; Provisional
 298-456 1.92e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 52.63  E-value: 1.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQR---------TEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPT 368
Cdd:PHA03247 2836 PTAPPPPPGPPPPSLPLGGSVAPGGDVRRRppsrspaakPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPP 2915

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  369 QLLHQNLPPVQAHPSAQSLSQPLSaynSSSLSLNSLSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQ 448
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQPPPPPPPRP---QPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASS 2992


                  ....*...
gi 767947344  449 PPAHSHHP 456
Cdd:PHA03247 2993 TPPLTGHS 3000
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 300-434 1.71e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 48.94  E-value: 1.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  300 PQVAQPIPQP-QTEPQLRAPSPDPDlvqrteAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHqnlPPV 378
Cdd:PRK14951  366 PAAAAEAAAPaEKKTPARPEAAAPA------AAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAA---PAA 436

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767947344  379 QAHPSAQSLSQPLSAYNSSSLSLNSLSSR-SSTPAKTQPAPPHISHHPSASPFPLSL 434
Cdd:PRK14951  437 APAAAPAAVALAPAPPAQAAPETVAIPVRvAPEPAVASAAPAPAAAPAAARLTPTEE 493
PHA03247 PHA03247
large tegument protein UL36; Provisional
 257-435 2.63e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 2.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  257 PEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPP 336
Cdd:PHA03247 2766 PPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP 2845

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  337 LST----------------QPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLS 400
Cdd:PHA03247 2846 PPPslplggsvapggdvrrRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP 2925

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767947344  401 LNSLSSRSSTPAKTQPAPPhishhPSASPFPLSLP 435
Cdd:PHA03247 2926 PPQPQPPPPPPPRPQPPLA-----PTTDPAGAGEP 2955
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 300-389 1.02e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 46.57  E-value: 1.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQllhqnLPPVQ 379
Cdd:pfam09770  272 PQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGR-----QAPII 346

                           90
                   ....*....|
gi 767947344   380 AHPsaQSLSQ 389
Cdd:pfam09770  347 THP--QQLAQ 354
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 298-394 2.02e-04

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 45.57  E-value: 2.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEA-PPQPPPLSTQPPQGPPEAQlQPAPQPQVQRPPR-----PQSPTQLL 371
Cdd:TIGR01628  383 RQLPMGSPMGGAMGQPPYYGQGPQQQFNGQPLGwPRMSMMPTPMGPGGPLRPN-GLAPMNAVRAPSRnaqnaAQKPPMQP 461

                           90       100
                   ....*....|....*....|...
gi 767947344   372 HQNLPPVQAHPSAQSLSQPLSAY 394
Cdd:TIGR01628  462 VMYPPNYQSLPLSQDLPQPQSTA 484
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 305-436 6.06e-04

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 43.95  E-value: 6.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  305 PIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSA 384
Cdd:PHA03269   27 PIPELHTSAATQKPDPAPAPHQAASRAPDPAVAPTSAASRKPDLAQAPTPAASEKFDPAPAPHQAASRAPDPAVAPQLAA 106

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767947344  385 QSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQPAPP-HISHHPSASPFPLSLPN 436
Cdd:PHA03269  107 APKPDAAEAFTSAAQAHEAPADAGTSAASKKPDPAaHTQHSPPPFAYTRSMEH 159
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 288-378 6.29e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 44.03  E-value: 6.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  288 PIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPdlvqrtEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSP 367
Cdd:PRK14950  364 PAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIP------PKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIP 437

                          90
                  ....*....|.
gi 767947344  368 TQLLHQNLPPV 378
Cdd:PRK14950  438 VDEKPKYTPPA 448
PTZ00121 PTZ00121
MAEBL; Provisional
 845-1008 6.55e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 6.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  845 KDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHL-P 923
Cdd:PTZ00121 1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKkA 1440

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  924 EKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKgEPAYENPKKSSEVKVKEERKEDHDLPPEAP 1003
Cdd:PTZ00121 1441 EEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAK-KKAEEAKKKADEAKKAAEAKKKADEAKKAE 1519


                  ....*
gi 767947344 1004 QTHRA 1008
Cdd:PTZ00121 1520 EAKKA 1524
PRK10819 PRK10819
transport protein TonB; Provisional
 300-419 7.60e-04

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 42.75  E-value: 7.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  300 PQVAQPI------PQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQP-----PQGPPEAQLQPAPQPQVQRPPRPqspt 368
Cdd:PRK10819   42 PAPAQPIsvtmvaPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPvvipkPEPKPKPKPKPKPKPVKKVEEQP---- 117

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767947344  369 qllHQNLPPVQAHPsaqslSQPLSAYNSSSLSLNSLSSRSSTPAKTQPAPP 419
Cdd:PRK10819  118 ---KREVKPVEPRP-----ASPFENTAPARPTSSTATAAASKPVTSVSSGP 160
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 262-364 8.94e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.92  E-value: 8.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  262 QDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAP-PQP---PPL 337
Cdd:PRK10263  398 QQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTyQQPaaqEPL 477

                          90       100
                  ....*....|....*....|....*..
gi 767947344  338 STQPPQGPPEAQLQPAPQPQVQRPPRP 364
Cdd:PRK10263  478 YQQPQPVEQQPVVEPEPVVEETKPARP 504
PRK11633 PRK11633
cell division protein DedD; Provisional
 297-367 1.09e-03

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 41.91  E-value: 1.09e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767947344  297 DPCPQVAQPIP-QP----QTEPQLR---APSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSP 367
Cdd:PRK11633   54 DMMPAATQALPtQPpegaAEAVRAGdaaAPSLDPATVAPPNTPVEPEPAPVEPPKPKPVEKPKPKPKPQQKVEAPPAPK 132
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 300-369 1.11e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.44  E-value: 1.11e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  300 PQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQ 369
Cdd:PRK07764  430 QPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAA 499
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 319-431 1.25e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.15  E-value: 1.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  319 SPDPDLVQrtEAPPQPPPLSTQPPQGPPEAQLQPAPQPQV-QRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSS 397
Cdd:PRK10263  730 SPMKALLD--DGPHEPLFTPIVEPVQQPQQPVAPQQQYQQpQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQP 807

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767947344  398 SLSLNSLSSRSSTPAKTQPAPPHISHHPSASPFP 431
Cdd:PRK10263  808 QQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQP 841
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
300-383 1.70e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.46  E-value: 1.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  300 PQVAQPIPQPQTEPQlRAPSPDPDLVQRTEAPPQPPPLSTQ---PPQGpPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLP 376
Cdd:PRK14971  381 PVFTQPAAAPQPSAA-AAASPSPSQSSAAAQPSAPQSATQPagtPPTV-SVDPPAAVPVNPPSTAPQAVRPAQFKEEKKI 458


                  ....*..
gi 767947344  377 PVQAHPS 383
Cdd:PRK14971  459 PVSKVSS 465
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
287-459 1.73e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  287 EPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAP---SPDPDLVQ-----------RTEAPPQPPPLSTQPPQGPPEAQLQP 352
Cdd:PRK12323  392 PAAAAPAPAAPPAAPAAAPAAAAAARAVAAAParrSPAPEALAaarqasargpgGAPAPAPAPAAAPAAAARPAAAGPRP 471

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  353 APQPQVQRPPRPQSPTQLLHQ--NLPPVQAHPSAQSLSQPlsaYNSSSLSLNSLSSRSSTPAKTQPAPPHISHHPSASPF 430
Cdd:PRK12323  472 VAAAAAAAPARAAPAAAPAPAddDPPPWEELPPEFASPAP---AQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAA 548

                         170       180
                  ....*....|....*....|....*....
gi 767947344  431 PLSLPNHSPLHSFTPTLQPPAHSHHPNMF 459
Cdd:PRK12323  549 PAPRAAAATEPVVAPRPPRASASGLPDMF 577
PRK12757 PRK12757
cell division protein FtsN; Provisional
 302-369 2.11e-03

cell division protein FtsN; Provisional


Pssm-ID: 237191 [Multi-domain]  Cd Length: 256  Bit Score: 41.57  E-value: 2.11e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767947344  302 VAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGP-PEAQLQPAPQPQVQRPPRPQSPTQ 369
Cdd:PRK12757  112 PQVPRSTVQIQQQAQQQQPPATTAQPQPVTPPRQTTAPVQPQTPaPVRTQPAAPVTQAVEAPKVEAEKE 180
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 298-385 2.15e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 2.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  298 PCPQVAQPIPQPQTePQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQlQPAPQPQVQRPPRPQSPTQLLHQNLPP 377
Cdd:PRK07764  406 PAAAPAPAAAAPAA-AAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSP-PPAAAPSAQPAPAPAAAPEPTAAPAPA 483


                  ....*...
gi 767947344  378 VQAHPSAQ 385
Cdd:PRK07764  484 PPAAPAPA 491
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 289-419 2.53e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 42.10  E-value: 2.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  289 IFEPVVLKDPCPQVAQPipqpqtepqlRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPqvqrPPRPQSPt 368
Cdd:PRK14950  355 VIEALLVPVPAPQPAKP----------TAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPV----PPRPVAP- 419

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767947344  369 qllhqnlPPVQAHPSAQSLSqplsaynssslslNSLSSRSSTPAKTQPAPP 419
Cdd:PRK14950  420 -------PVPHTPESAPKLT-------------RAAIPVDEKPKYTPPAPP 450
DUF6264 pfam19779
Family of unknown function (DUF6264); This family of putative integral membrane proteins is ...
 311-364 4.13e-03

Family of unknown function (DUF6264); This family of putative integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 179 and 218 amino acids in length.


Pssm-ID: 466182  Cd Length: 182  Bit Score: 39.56  E-value: 4.13e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767947344   311 TEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGP-------PEAQLQPAPQPQVQRPPRP 364
Cdd:pfam19779    9 PPGWQRAPIGDPAAAAAAAPPAAPAPAAPAPPAAPaappaapPPPGAPAPGAPAAARRARR 69
PHA02682 PHA02682
ORF080 virion core protein; Provisional
 298-390 4.17e-03

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 40.61  E-value: 4.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  298 PCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAP-PQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLP 376
Cdd:PHA02682  103 PAPAVTCPAPAPACPPATAPTCPPPAVCPAPARPaPACPPSTRQCPPAPPLPTPKPAPAAKPIFLHNQLPPPDYPAASCP 182

                          90
                  ....*....|....
gi 767947344  377 PVQAHPSAQSLSQP 390
Cdd:PHA02682  183 TIETAPAASPVLEP 196
PRK10819 PRK10819
transport protein TonB; Provisional
 286-390 4.50e-03

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 40.44  E-value: 4.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  286 KEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRaPSPDPDLVQRTEAPPQPP--PLSTQPPQ-GPPEAQLQPAPQPQVQRPP 362
Cdd:PRK10819   72 VEPEPEPEPIPEPPKEAPVVIPKPEPKPKPK-PKPKPKPVKKVEEQPKREvkPVEPRPASpFENTAPARPTSSTATAAAS 150

                          90       100
                  ....*....|....*....|....*...
gi 767947344  363 RPQSptqllhqnlpPVQAHPSAQSLSQP 390
Cdd:PRK10819  151 KPVT----------SVSSGPRALSRNQP 168
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 288-392 5.77e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 40.86  E-value: 5.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  288 PIFEPVVLKDPCPQVAQPIPQPQTEPQLR-----APSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPP 362
Cdd:PRK14949  681 LATHQSVPEAALASGSAPAPPPVPDPYDRppweeAPEVASANDGPNNAAEGNLSESVEDASNSELQAVEQQATHQPQVQA 760

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767947344  363 RPQSPTQ---LLHQNLPPVQAHPS-AQSLSQPLS 392
Cdd:PRK14949  761 EAQSPASttaLTQTSSEVQDTELNlVLLSSGSIT 794
PHA03378 PHA03378
EBNA-3B; Provisional
 305-392 6.55e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 40.82  E-value: 6.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  305 PIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSA 384
Cdd:PHA03378  743 RARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMPRAAPGQQGPTK 822


                  ....*...
gi 767947344  385 QSLSQPLS 392
Cdd:PHA03378  823 QILRQLLT 830
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 326-446 6.90e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 40.91  E-value: 6.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344   326 QRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPR---------PQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNS 396
Cdd:pfam03154  422 QQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQspfpqhpfvPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVS 501

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 767947344   397 SSLSLNSLSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPT 446
Cdd:pfam03154  502 SSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPS 551
PHA03247 PHA03247
large tegument protein UL36; Provisional
 263-631 7.22e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 7.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  263 DAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPP 342
Cdd:PHA03247 2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLAD 2700

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  343 QGPPEAQLQPAPQPQVQRPPRPQSPtQLLHQNLPPVQAHPSAQSLSQ-----------PLSAYNSSSLSLNSLSSRSSTP 411
Cdd:PHA03247 2701 PPPPPPTPEPAPHALVSATPLPPGP-AAARQASPALPAAPAPPAVPAgpatpggparpARPPTTAGPPAPAPPAAPAAGP 2779

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  412 AKTQPAPPHISHHPS--ASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSE 489
Cdd:PHA03247 2780 PRRLTRPAVASLSESreSLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPG 2859

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  490 QDILRQELNTRFLASQSAD---RGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPmvrTP 566
Cdd:PHA03247 2860 GDVRRRPPSRSPAAKPAAParpPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPP---PP 2936

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767947344  567 GRnfdkyptkvdpfyrhslfhsyPPavsgiPPMIPPTGPFGslQGAFQPKTSNPIDVAARPGTVP 631
Cdd:PHA03247 2937 PR---------------------PQ-----PPLAPTTDPAG--AGEPSGAVPQPWLGALVPGRVA 2973
PRK01297 PRK01297
ATP-dependent RNA helicase RhlB; Provisional
 308-370 7.40e-03

ATP-dependent RNA helicase RhlB; Provisional


Pssm-ID: 234938 [Multi-domain]  Cd Length: 475  Bit Score: 40.28  E-value: 7.40e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767947344  308 QPQTEPQLRAPSPDPdlvqRTEAPPQPPPLSTQPPQGPPEAQLQPAP-QPQVQRPPRPQSPTQL 370
Cdd:PRK01297   16 QPAPAPPSPAAAPAP----PPPAKTAAPATKAAAPAAAAPRAEKPKKdKPRRERKPKPASLWKL 75
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
298-390 7.84e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 40.53  E-value: 7.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  298 PCPQVAQPIPQPQ-TEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQspTQLLHQNLP 376
Cdd:PRK14971  409 AQPSAPQSATQPAgTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLGPSTLRPIQEK--AEQATGNIK 486

                          90
                  ....*....|....
gi 767947344  377 PVQAHPSAQSLSQP 390
Cdd:PRK14971  487 EAPTGTQKEIFTEE 500
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 303-393 8.15e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 8.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  303 AQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPtqllhqnlPPVQAHP 382
Cdd:PRK07764  429 PQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAA--------PAAPAAP 500

                          90
                  ....*....|.
gi 767947344  383 SAQSLSQPLSA 393
Cdd:PRK07764  501 AAPAGADDAAT 511
PHA03378 PHA03378
EBNA-3B; Provisional
 290-451 9.43e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 40.44  E-value: 9.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  290 FEPVVLKDP--CPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSP 367
Cdd:PHA03378  643 FNVLVFPTPhqPPQVEITPYKPTWTQIGHIPYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATG 722

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  368 TQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPlhsfTPTL 447
Cdd:PHA03378  723 RARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAP----TPQP 798


                  ....
gi 767947344  448 QPPA 451
Cdd:PHA03378  799 PPQA 802
PRK10819 PRK10819
transport protein TonB; Provisional
 297-392 9.54e-03

transport protein TonB; Provisional


Pssm-ID: 236768 [Multi-domain]  Cd Length: 246  Bit Score: 39.28  E-value: 9.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767947344  297 DPCPQVAQPIPQPQTEPQlraPSPDPdlvqrTEAPPQPPPLSTQPPQGPPEAQLQPAP--------------QPQVQRPP 362
Cdd:PRK10819   58 LEPPQAVQPPPEPVVEPE---PEPEP-----IPEPPKEAPVVIPKPEPKPKPKPKPKPkpvkkveeqpkrevKPVEPRPA 129

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 767947344  363 RP---QSPTQLLHQNLPPVQAHP--SAQSLSQPLS 392
Cdd:PRK10819  130 SPfenTAPARPTSSTATAAASKPvtSVSSGPRALS 164
PRK11633 PRK11633
cell division protein DedD; Provisional
 291-357 9.83e-03

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 39.22  E-value: 9.83e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767947344  291 EPVVLKDPCPQVAQPIPQPQTEPQlrapsPDPDLVQRTEAPPQPpplstqPPQGPPEAQLQPAPQPQ 357
Cdd:PRK11633   93 PNTPVEPEPAPVEPPKPKPVEKPK-----PKPKPQQKVEAPPAP------KPEPKPVVEEKAAPTGK 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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