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Conserved domains on  [gi|767956446|ref|XP_011516600|]
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tetratricopeptide repeat protein 16 isoform X16 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1000094)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
260-413 2.33e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.43  E-value: 2.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 260 ILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEdmvrqaqrqlllTYNDFAV 339
Cdd:COG0457   17 AYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE------------ALNNLGL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767956446 340 HCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-359 6.71e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 6.71e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTFVLYLQG 143
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDR-------AEALLELA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 144 QCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLC 223
Cdd:COG2956   84 QDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 224 YRDLHSALLLNPKHPQARMLLQKmvaqaqqarqdagILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDG 303
Cdd:COG2956  164 IEALEKALKLDPDCARALLLLAE-------------LYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767956446 304 AVEDFLKVLDmvtEDQEDMVRQAQRQLLLtyndfavhcyRQGAYQEGVLLLNKALR 359
Cdd:COG2956  231 ALELLRKALE---LDPSDDLLLALADLLE----------RKEGLEAALALLERQLR 273
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
260-413 2.33e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.43  E-value: 2.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 260 ILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEdmvrqaqrqlllTYNDFAV 339
Cdd:COG0457   17 AYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE------------ALNNLGL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767956446 340 HCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-359 6.71e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 6.71e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTFVLYLQG 143
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDR-------AEALLELA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 144 QCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLC 223
Cdd:COG2956   84 QDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 224 YRDLHSALLLNPKHPQARMLLQKmvaqaqqarqdagILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDG 303
Cdd:COG2956  164 IEALEKALKLDPDCARALLLLAE-------------LYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767956446 304 AVEDFLKVLDmvtEDQEDMVRQAQRQLLLtyndfavhcyRQGAYQEGVLLLNKALR 359
Cdd:COG2956  231 ALELLRKALE---LDPSDDLLLALADLLE----------RKEGLEAALALLERQLR 273
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-413 5.41e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 73.96  E-value: 5.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446   50 PKVTGLTVPL---------KVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRR 120
Cdd:TIGR02917   2 IKITALLCIAlalsacgdqSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  121 AYSLQQDNCKHLERLTFVLYLQGQclfeqcafldalnvFSHAAELQPEKPCFRYRCMACLLALKQHqACLTLITNELKQD 200
Cdd:TIGR02917  82 ALSLGYPKNQVLPLLARAYLLQGK--------------FQQVLDELPGKTLLDDEGAAELLALRGL-AYLGLGQLELAQK 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  201 TTNADVYIFRARLYNFLQKPHL--CYRDLHSA-------LLLNPKHPQARMLLQKmvaqaqqarqdagILAVQGKLQHAL 271
Cdd:TIGR02917 147 SYEQALAIDPRSLYAKLGLAQLalAENRFDEAralidevLTADPGNVDALLLKGD-------------LLLSLGNIELAL 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  272 QRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAvedflkvldmvTEDQEDMVRQAQRQLLLTYNDFAVHcYRQGAYQEGV 351
Cdd:TIGR02917 214 AAYRKAIALRPNNIAVLLALATILIEAGEFEEA-----------EKHADALLKKAPNSPLAHYLKALVD-FQKKNYEDAR 281

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767956446  352 LLLNKALR-DEQQEKGLYInRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:TIGR02917 282 ETLQDALKsAPEYLPALLL-AGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLG 343
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 63-128 3.70e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 45.31  E-value: 3.70e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767956446  63 EYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDN 128
Cdd:cd24142    2 ELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
TPR_12 pfam13424
Tetratricopeptide repeat;
329-397 5.64e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 5.64e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767956446  329 QLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKG--------LYINRGDCFFQLGNLAFAEADYQQALALSPQ 397
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGpdhpltatTLLNLGRLYLELGRYEEALELLERALALAEK 77
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 76-124 1.22e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 44.01  E-value: 1.22e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 767956446  76 DWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSL 124
Cdd:PLN03088  17 DFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIEL 65
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 368-398 6.01e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 6.01e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 767956446   368 YINRGDCFFQLGNLAFAEADYQQALALSPQD 398
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_11 pfam13414
TPR repeat;
62-108 5.26e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 34.75  E-value: 5.26e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 767956446   62 REYYSRGQqcleqadWETAVLLFSRALHLDPQLVDFYALRAEAYLQL 108
Cdd:pfam13414   2 DAYYEQGK-------YEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
260-413 2.33e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.43  E-value: 2.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 260 ILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEdmvrqaqrqlllTYNDFAV 339
Cdd:COG0457   17 AYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE------------ALNNLGL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767956446 340 HCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-359 6.71e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 6.71e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTFVLYLQG 143
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDR-------AEALLELA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 144 QCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLC 223
Cdd:COG2956   84 QDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 224 YRDLHSALLLNPKHPQARMLLQKmvaqaqqarqdagILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDG 303
Cdd:COG2956  164 IEALEKALKLDPDCARALLLLAE-------------LYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767956446 304 AVEDFLKVLDmvtEDQEDMVRQAQRQLLLtyndfavhcyRQGAYQEGVLLLNKALR 359
Cdd:COG2956  231 ALELLRKALE---LDPSDDLLLALADLLE----------RKEGLEAALALLERQLR 273
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-413 5.41e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 73.96  E-value: 5.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446   50 PKVTGLTVPL---------KVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRR 120
Cdd:TIGR02917   2 IKITALLCIAlalsacgdqSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  121 AYSLQQDNCKHLERLTFVLYLQGQclfeqcafldalnvFSHAAELQPEKPCFRYRCMACLLALKQHqACLTLITNELKQD 200
Cdd:TIGR02917  82 ALSLGYPKNQVLPLLARAYLLQGK--------------FQQVLDELPGKTLLDDEGAAELLALRGL-AYLGLGQLELAQK 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  201 TTNADVYIFRARLYNFLQKPHL--CYRDLHSA-------LLLNPKHPQARMLLQKmvaqaqqarqdagILAVQGKLQHAL 271
Cdd:TIGR02917 147 SYEQALAIDPRSLYAKLGLAQLalAENRFDEAralidevLTADPGNVDALLLKGD-------------LLLSLGNIELAL 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  272 QRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAvedflkvldmvTEDQEDMVRQAQRQLLLTYNDFAVHcYRQGAYQEGV 351
Cdd:TIGR02917 214 AAYRKAIALRPNNIAVLLALATILIEAGEFEEA-----------EKHADALLKKAPNSPLAHYLKALVD-FQKKNYEDAR 281

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767956446  352 LLLNKALR-DEQQEKGLYInRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:TIGR02917 282 ETLQDALKsAPEYLPALLL-AGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLG 343
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 260-398 8.90e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.21  E-value: 8.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 260 ILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEdmvrqaqrqlllTYNDFAV 339
Cdd:COG4783   13 ALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPE------------ARLNLGL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767956446 340 HCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQD 398
Cdd:COG4783   81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 260-416 3.52e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.10  E-value: 3.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 260 ILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEdmvrqaqrqlllTYNDFAV 339
Cdd:COG3914   87 LLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE------------AYLNLGE 154

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767956446 340 HCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGAntRMGLLQEKMGFCE 416
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA--HSNLLFALRQACD 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
64-280 1.59e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.87  E-value: 1.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTFVLYLQG 143
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD-------AEALNNLG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 144 QCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLC 223
Cdd:COG0457   84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEA 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767956446 224 YRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIEN 280
Cdd:COG0457  164 LELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALA 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
278-413 2.19e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.49  E-value: 2.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 278 IENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMvtedqedmvrqaQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKA 357
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL------------DPDDAEALYNLGLAYLRLGRYEEALADYEQA 68

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767956446 358 LRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG0457   69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 62-214 1.06e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.47  E-value: 1.06e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  62 REYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDnckHLErltfVLYL 141
Cdd:COG3914   79 ALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPD---FAE----AYLN 151

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767956446 142 QGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLY 214
Cdd:COG3914  152 LGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL 224
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 270-399 1.34e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.86  E-value: 1.34e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 270 ALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQllltyndfavhcYRQGAYQE 349
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAL------------LAAGDTEE 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 767956446 350 GVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDE 399
Cdd:COG4235   70 AEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 180-413 1.40e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.67  E-value: 1.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 180 LLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKmvaqaqqarqdag 259
Cdd:COG2956   18 YLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQ------------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 260 ILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLlltyndfav 339
Cdd:COG2956   85 DYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL--------- 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767956446 340 hcyRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG2956  156 ---EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLG 226
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 60-188 1.42e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.05  E-value: 1.42e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  60 KVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTFVL 139
Cdd:COG4783    3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE-------PEAR 75

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 767956446 140 YLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQA 188
Cdd:COG4783   76 LNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDE 124
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 140-414 5.97e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.74  E-value: 5.97e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 140 YLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQK 219
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 220 PHLCYRDLHSALLLNPKHPQARMLLqkmvaqaqqarqdAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQ 299
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLL-------------AEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 300 EFDGAVEDFLKVLdmvtEDQEDMVRqAQRQLLLTYndfavhcYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLG 379
Cdd:COG2956  159 DYDEAIEALEKAL----KLDPDCAR-ALLLLAELY-------LEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLG 226

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 767956446 380 NLAFAEADYQQALALSPQDEGANTRMGLLQEKMGF 414
Cdd:COG2956  227 DPEEALELLRKALELDPSDDLLLALADLLERKEGL 261
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
164-412 6.59e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 59.25  E-value: 6.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 164 ELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARML 243
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 244 LQKmvaqaqqarqdagILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMV 323
Cdd:COG0457   82 LGL-------------ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALY 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 324 RQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCF-FQLGNLAFAEADYQQALALSPQDEGAN 402
Cdd:COG0457  149 NLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLlALEQALRKKLAILTLAALAELLLLALA 228

                        250
                 ....*....|
gi 767956446 403 TRMGLLQEKM 412
Cdd:COG0457  229 LLLALRLAAL 238
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 207-413 6.98e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.36  E-value: 6.98e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 207 YIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKmvaqaqqarqdagILAVQGKLQHALQRINRAIENNPLDPS 286
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGN-------------LYRRRGEYDRAIRIHQKLLERDPDRAE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 287 LFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEdmvrqAQRQLLLTYndfavhcYRQGAYQEGVLLLNKALRDEQQEKG 366
Cdd:COG2956   78 ALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE-----ALRLLAEIY-------EQEGDWEKAIEVLERLLKLGPENAH 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 767956446 367 LYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG2956  146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQG 192
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
270-421 9.42e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.39  E-value: 9.42e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 270 ALQRINRAIENnPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLdmvtEDQEDMVRqaqrqlllTYNDFAVHCYRQGAYQE 349
Cdd:COG4785   59 AAERIDRALAL-PDLAQLYYERGVAYDSLGDYDLAIADFDQAL----ELDPDLAE--------AYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767956446 350 GVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQRRKW 421
Cdd:COG4785  126 ALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKALALL 197
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
88-390 1.41e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.09  E-value: 1.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  88 LHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLTFVLYLQGQclfeqcaFLDALNVFSHAAELQP 167
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGR-------YEEALADYEQALELDP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 168 EkpcfryrcmacllalkqhqacltlitnelkqdttNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKm 247
Cdd:COG0457   74 D----------------------------------DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGL- 118

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 248 vaqaqqarqdagILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQ 327
Cdd:COG0457  119 ------------ALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEA 186

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767956446 328 RQLLLTYNDFAvhcyRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQ 390
Cdd:COG0457  187 ALALAAAEVLL----ALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 190-327 5.29e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 54.24  E-value: 5.29e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 190 LTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLqkmvaqaqqarqdAGILAVQGKLQH 269
Cdd:COG4235    3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL-------------AEALLAAGDTEE 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767956446 270 ALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQ 327
Cdd:COG4235   70 AEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEAS 127
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 58-181 1.12e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.31  E-value: 1.12e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKhlerltf 137
Cdd:COG3914  109 PDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAE------- 181

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 767956446 138 VLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLL 181
Cdd:COG3914  182 ALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALR 225
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
58-211 5.81e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.00  E-value: 5.81e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTF 137
Cdd:COG4785   70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDY-------AY 142

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767956446 138 VLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLIT-----NELKQDTTNADVYIFRA 211
Cdd:COG4785  143 AYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKALALLLEdwataYLLQGDTEEARELFKLA 221
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 210-413 7.24e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.61  E-value: 7.24e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 210 RARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFL 289
Cdd:COG3914    9 LAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 290 frgtmyRRLQEFDGAVEDFLKVLdmvtedqedmvrQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYI 369
Cdd:COG3914   89 ------QALGRYEEALALYRRAL------------ALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYL 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 767956446 370 NRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG3914  151 NLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLG 194
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 63-244 7.76e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.61  E-value: 7.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  63 EYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLTFVLYLQ 142
Cdd:COG3914   46 LLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLAL 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 143 GQclfeqcaFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHL 222
Cdd:COG3914  126 GR-------LEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEE 198

                        170       180
                 ....*....|....*....|..
gi 767956446 223 CYRDLHSALLLNPKHPQARMLL 244
Cdd:COG3914  199 AIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 291-413 7.89e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.96  E-value: 7.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 291 RGTMYRRLQEFDGAVEDFLKVLDMVTEDQEdmvrqAQRQLLLTYndfavhcYRQGAYQEGVLLLNKALRDEQQEKGLYIN 370
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPE-----AFALLGEIL-------LQLGDLDEAIVLLHEALELDPDEPEARLN 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 767956446 371 RGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG4783   78 LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
264-405 2.41e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.45  E-value: 2.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 264 QGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAqrqllLTYndfavhcYR 343
Cdd:COG4785   86 LGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG-----IAL-------YY 153

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767956446 344 QGAYQEGVLLLNKALRDEQQEKGLYINRgdcffqlgNLAFAEADYQQALALSPQDEGANTRM 405
Cdd:COG4785  154 LGRYELAIADLEKALELDPNDPERALWL--------YLAERKLDPEKALALLLEDWATAYLL 207
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-281 3.74e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 3.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTFVLYLQG 143
Cdd:COG2956   79 LLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN-------AHAYCELA 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 144 QCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLC 223
Cdd:COG2956  152 ELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEA 231

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767956446 224 YRDLHSALLLNPKHPQARMLLQkmvaqaqqarqdagILAVQGKLQHALQRINRAIENN 281
Cdd:COG2956  232 LELLRKALELDPSDDLLLALAD--------------LLERKEGLEAALALLERQLRRH 275
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 64-410 4.22e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 52.29  E-value: 4.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446   64 YYSRGQQCLEQ-ADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRrAYSLQQD-----NCKHLERL-- 135
Cdd:TIGR00990 162 YYSNRAACHNAlGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDLT-ASCIIDGfrneqSAQAVERLlk 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  136 TFVLYLQGQCLFEQCAFLDAlnVFSHAAELQPEKPCFRYRCMACLLALKQH----QACLTLITNELKQDTTNAD-VYIFR 210
Cdd:TIGR00990 241 KFAESKAKEILETKPENLPS--VTFVGNYLQSFRPKPRPAGLEDSNELDEEtgngQLQLGLKSPESKADESYEEaARAFE 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  211 ARLYNFLQKPHLCYRDLHSALL--LNPKHPQARMLLQKMV----AQAQQARQDAGILAVQGKLQHALQRINRAIENNPLD 284
Cdd:TIGR00990 319 KALDLGKLGEKEAIALNLRGTFkcLKGKHLEALADLSKSIeldpRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSED 398

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  285 PSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTE-------------------DQEDMVRQAQRQLLLT---YNDFAVHCY 342
Cdd:TIGR00990 399 PDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDfifshiqlgvtqykegsiaSSMATFRRCKKNFPEApdvYNYYGELLL 478

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767956446  343 RQGAYQEGVLLLNKALRDEQQEKGLY------INRGDCFFQ-LGNLAFAEADYQQALALSPQDEGANTRMG--LLQE 410
Cdd:TIGR00990 479 DQNKFDEAIEKFDTAIELEKETKPMYmnvlplINKALALFQwKQDFIEAENLCEKALIIDPECDIAVATMAqlLLQQ 555
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
64-233 4.59e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.78  E-value: 4.59e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLTFVLYLQG 143
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 144 QclfeqcaFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLC 223
Cdd:COG0457  159 R-------YEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231

                        170
                 ....*....|
gi 767956446 224 YRDLHSALLL 233
Cdd:COG0457  232 ALRLAALALY 241
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 80-213 5.36e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.46  E-value: 5.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  80 AVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTFVLYLQGQCLFEQCAFLDALNVF 159
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN-------ADALLDLAEALLAAGDTEEAEELL 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767956446 160 SHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARL 213
Cdd:COG4235   75 ERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 64-168 5.79e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.46  E-value: 5.79e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNckhlerlTFVLYLQG 143
Cdd:COG4235   20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDN-------PEALYLLG 92

                         90       100
                 ....*....|....*....|....*
gi 767956446 144 QCLFEQCAFLDALNVFSHAAELQPE 168
Cdd:COG4235   93 LAAFQQGDYAEAIAAWQKLLALLPA 117
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 324-413 1.83e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 1.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 324 RQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANT 403
Cdd:COG5010   47 RDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYS 126

                         90
                 ....*....|
gi 767956446 404 RMGLLQEKMG 413
Cdd:COG5010  127 NLAALLLSLG 136
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
72-168 4.38e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 4.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  72 LEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQnLRRAYSLQQDNCKHLERLTFVLYLQGQclfeqca 151
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGD------- 74

                         90
                 ....*....|....*..
gi 767956446 152 FLDALNVFSHAAELQPE 168
Cdd:COG3063   75 YDEALAYLERALELDPS 91
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 59-422 7.30e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 48.06  E-value: 7.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446   59 LKVREyysRGQQCLEQADWETAVLLFSRALHLDPQLVdFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERltfv 138
Cdd:TIGR00990 128 AKLKE---KGNKAYRNKDFNKAIKLYSKAIECKPDPV-YYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNR---- 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  139 lylqgqclfeQCAFLDALNVFSHAAeLQPEKPC----FRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRArly 214
Cdd:TIGR00990 200 ----------RANAYDGLGKYADAL-LDLTASCiidgFRNEQSAQAVERLLKKFAESKAKEILETKPENLPSVTFVG--- 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  215 NFLQ--KPHLCYRDLHSALLLNPKhpQARMLLQKmvaqaqqarqdaGILAVQGKLQHALQRINRAIEN----NPLDPSLF 288
Cdd:TIGR00990 266 NYLQsfRPKPRPAGLEDSNELDEE--TGNGQLQL------------GLKSPESKADESYEEAARAFEKaldlGKLGEKEA 331

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  289 L---FRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLL-----TYNDFavhcyrqgayqegvlllNKALRD 360
Cdd:TIGR00990 332 IalnLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELgdpdkAEEDF-----------------DKALKL 394

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  361 EQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG--------FCEQRRKWP 422
Cdd:TIGR00990 395 NSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGsiassmatFRRCKKNFP 464
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 42-396 8.49e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 8.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446   42 FQSICDVKPKVTGLTVPLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVdfYALRAEAYLQLC--DFSSAAQNLR 119
Cdd:TIGR02917 106 FQQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSL--YAKLGLAQLALAenRFDEARALID 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  120 RAYSLQQDNCKhlerltfVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQ 199
Cdd:TIGR02917 184 EVLTADPGNVD-------ALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKK 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  200 DTTNADVYIFRArLYNFLQKPHLCYRD-LHSALLLNP-----------------KHPQARMLLQKMVAQAQQARQDAGIL 261
Cdd:TIGR02917 257 APNSPLAHYLKA-LVDFQKKNYEDAREtLQDALKSAPeylpalllagaseyqlgNLEQAYQYLNQILKYAPNSHQARRLL 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  262 AV----QGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDMVRQAQRQLLLTYNDF 337
Cdd:TIGR02917 336 ASiqlrLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSE 415

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  338 AVHCYRQGAYQE------GVLLLNKALRDEQQEKGL----------------YINRGDCFFQLGNLAFAEADYQQALALS 395
Cdd:TIGR02917 416 AIADLETAAQLDpelgraDLLLILSYLRSGQFDKALaaakklekkqpdnaslHNLLGAIYLGKGDLAKAREAFEKALSIE 495


                  .
gi 767956446  396 P 396
Cdd:TIGR02917 496 P 496
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 72-167 8.56e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 8.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  72 LEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLTFVLYLQGQclfeqca 151
Cdd:COG5010   65 NKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQ------- 137

                         90
                 ....*....|....*.
gi 767956446 152 FLDALNVFSHAAELQP 167
Cdd:COG5010  138 DDEAKAALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 64-143 1.23e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 47.68  E-value: 1.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLTFVLYLQG 143
Cdd:COG3914  149 YLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQAC 228
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
295-396 3.08e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 3.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 295 YRRLQEFDGAVEDFLKVLdmvtedqedmvrQAQRQLLLTYNDFAVHCYRQGAYQEGvLLLNKALRDEQQEKGLYINRGDC 374
Cdd:COG3063    2 YLKLGDLEEAEEYYEKAL------------ELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAEL 68

                         90       100
                 ....*....|....*....|..
gi 767956446 375 FFQLGNLAFAEADYQQALALSP 396
Cdd:COG3063   69 LLELGDYDEALAYLERALELDP 90
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 63-128 3.70e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 45.31  E-value: 3.70e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767956446  63 EYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDN 128
Cdd:cd24142    2 ELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 321-413 5.07e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 42.69  E-value: 5.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 321 DMVRQAQRQLLLTYNDF------AVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALAL 394
Cdd:COG4235    1 EAIARLRQALAANPNDAegwlllGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90
                 ....*....|....*....
gi 767956446 395 SPQDEGANTRMGLLQEKMG 413
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQG 99
TPR_12 pfam13424
Tetratricopeptide repeat;
329-397 5.64e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 5.64e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767956446  329 QLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKG--------LYINRGDCFFQLGNLAFAEADYQQALALSPQ 397
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGpdhpltatTLLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 232-396 7.07e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.03  E-value: 7.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 232 LLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPLDPSLFLFRGTMYRRLQEFDGAVEDFLKV 311
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 312 LDMVTEDQEdmvrqaqrqlllTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQA 391
Cdd:COG5010   81 LQLDPNNPE------------LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRA 148


                 ....*
gi 767956446 392 LALSP 396
Cdd:COG5010  149 LGTSP 153
TPR_1 pfam00515
Tetratricopeptide repeat;
368-398 7.26e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.71  E-value: 7.26e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 767956446  368 YINRGDCFFQLGNLAFAEADYQQALALSPQD 398
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 58-279 7.79e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.97  E-value: 7.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446   58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLTF 137
Cdd:TIGR00990 362 PRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGV 441

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  138 VLYLQG-----QCLFEQCA--FLDALNVFSHAAELQPEKPCFRYrcmacllALKQHQACLTLiTNELKQDTTNADVYIFR 210
Cdd:TIGR00990 442 TQYKEGsiassMATFRRCKknFPEAPDVYNYYGELLLDQNKFDE-------AIEKFDTAIEL-EKETKPMYMNVLPLINK 513

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767956446  211 ARLY-----NFLQKPHLCYRdlhsALLLNPKHPQARMLLQKMvaqaqqarqdagiLAVQGKLQHALQRINRAIE 279
Cdd:TIGR00990 514 ALALfqwkqDFIEAENLCEK----ALIIDPECDIAVATMAQL-------------LLQQGDVDEALKLFERAAE 570
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 138-282 9.75e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 9.75e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 138 VLYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFL 217
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767956446 218 QKPHLCYRDLHSALLLNPKHPQARMLLQKmvaqaqqarqdagILAVQGKLQHALQRINRAIENNP 282
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEAYLRLAR-------------AYRALGRPDEAIAALEKALELDP 137
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 76-124 1.22e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 44.01  E-value: 1.22e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 767956446  76 DWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSL 124
Cdd:PLN03088  17 DFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIEL 65
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 58-143 1.37e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.56  E-value: 1.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  58 PLKVREYYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLTF 137
Cdd:COG2956  175 PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADL 254


                 ....*.
gi 767956446 138 VLYLQG 143
Cdd:COG2956  255 LERKEG 260
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
72-244 1.60e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.98  E-value: 1.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446  72 LEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLcDFSSAAQNLRRAYSLQQDNCKHLERLTFVLYLQGQCLFEQCA 151
Cdd:COG4785   10 LALALAAAAASKAAILLAALLFAAVLALAIALADLAL-ALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 152 FLDALNVFSHAAELQPEKP-CFRYRCMAcLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSA 230
Cdd:COG4785   89 YDLAIADFDQALELDPDLAeAYNNRGLA-YLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKA 167

                        170
                 ....*....|....
gi 767956446 231 LLLNPKHPQARMLL 244
Cdd:COG4785  168 LELDPNDPERALWL 181
TPR_11 pfam13414
TPR repeat;
372-413 1.73e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 38.61  E-value: 1.73e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 767956446  372 GDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 368-398 6.01e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 6.01e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 767956446   368 YINRGDCFFQLGNLAFAEADYQQALALSPQD 398
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 139-247 6.92e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.60  E-value: 6.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 139 LYLQGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMACLLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQ 218
Cdd:COG4235   20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQG 99

                         90       100
                 ....*....|....*....|....*....
gi 767956446 219 KPHLCYRDLHSALLLNPKHPQARMLLQKM 247
Cdd:COG4235  100 DYAEAIAAWQKLLALLPADAPARLLEASI 128
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 101-178 9.31e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.07  E-value: 9.31e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767956446 101 RAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLtfvlylqGQCLFEQCAFLDALNVFSHAAELQPEKPCFRYRCMA 178
Cdd:cd24142    6 KAEELLDQGNFELALKFLQRALELEPNNVEALELL-------GEILLELGDVEEAREVLLRAIELDPDGGYEKYLYLG 76
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 204-361 1.47e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.17  E-value: 1.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 204 ADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGKLQHALQRINRAIENNPL 283
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767956446 284 DPSLFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEdmvrqaqrqlllTYNDFAVHCYRQGAYQEGVLLLNKALRDE 361
Cdd:COG5010   87 NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN------------AYSNLAALLLSLGQDDEAKAALQRALGTS 152
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 64-128 2.32e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 2.32e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDN 128
Cdd:COG4235   54 LLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
342-413 2.40e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.07  E-value: 2.40e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767956446 342 YRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEAdYQQALALSPQDEGANTRMGLLQEKMG 413
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG 73
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 180-294 4.16e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.29  E-value: 4.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767956446 180 LLALKQHQACLTLITNELKQDTTNADVYIFRARLYNFLQKPHLCYRDLHSALLLNPKHPQARMLLqkmvaqaqqarqdaG 259
Cdd:COG4235   27 YLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLL--------------G 92

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 767956446 260 ILAVQ-GKLQHALQRINRAIENNPLDPSLFLFRGTM 294
Cdd:COG4235   93 LAAFQqGDYAEAIAAWQKLLALLPADAPARLLEASI 128
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 367-397 4.60e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 34.42  E-value: 4.60e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 767956446  367 LYINRGDCFFQLGNLAFAEADYQQALALSPQ 397
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_11 pfam13414
TPR repeat;
62-108 5.26e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 34.75  E-value: 5.26e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 767956446   62 REYYSRGQqcleqadWETAVLLFSRALHLDPQLVDFYALRAEAYLQL 108
Cdd:pfam13414   2 DAYYEQGK-------YEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 64-125 9.52e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 36.86  E-value: 9.52e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767956446  64 YYSRGQQCLEQADWETAVLLFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQ 125
Cdd:COG5010   91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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