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Conserved domains on  [gi|767957741|ref|XP_011517102|]
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methylglutaconyl-CoA hydratase, mitochondrial isoform X8 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 99-227 3.14e-33

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 121.45  E-value: 3.14e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PLN02600   5 IVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSL 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 767957741 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PLN02600  85 EALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPG 133
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
 99-227 3.14e-33

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 121.45  E-value: 3.14e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PLN02600   5 IVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSL 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 767957741 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PLN02600  85 EALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPG 133
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 98-233 1.53e-26

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 102.25  E-value: 1.53e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSS--EVGPFVSKIRAVI 175
Cdd:cd06558    8 GVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALSDAgeEARAFIRELQELL 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767957741 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGVTSST 233
Cdd:cd06558   87 RALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQR 144
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 98-228 1.45e-24

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 98.32  E-value: 1.45e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIN 176
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 767957741 177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:COG1024   87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGG 138
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 99-228 1.92e-16

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 76.24  E-value: 1.92e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741   99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLL 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 767957741  179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:pfam00378  85 YTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGA 134
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 99-228 6.76e-08

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 52.92  E-value: 6.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741   99 IVVLGINRAYGK-NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIN 176
Cdd:TIGR02441  23 VAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMiAACKTAQEVTQLSQEGQEMFE 102

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767957741  177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGG 228
Cdd:TIGR02441 103 RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGA 156
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
 99-227 3.14e-33

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 121.45  E-value: 3.14e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PLN02600   5 IVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSL 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 767957741 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PLN02600  85 EALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPG 133
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 99-227 1.03e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 120.22  E-value: 1.03e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK07657  14 VVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTMEMV 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 767957741 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PRK07657  94 EQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPG 142
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 98-233 1.53e-26

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 102.25  E-value: 1.53e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSS--EVGPFVSKIRAVI 175
Cdd:cd06558    8 GVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALSDAgeEARAFIRELQELL 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767957741 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGVTSST 233
Cdd:cd06558   87 RALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQR 144
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 98-228 1.45e-24

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 98.32  E-value: 1.45e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIN 176
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 767957741 177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:COG1024   87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGG 138
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
111-227 3.13e-18

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 83.76  E-value: 3.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERA---KMSSSEVGPFVSKIRAVINDIANLPVPTIA 187
Cdd:PRK11730  29 NKLDRATLASLGEALDALEAQSDLKGLLLTSAKD-AFIVGADITEFLslfAAPEEELSQWLHFANSIFNRLEDLPVPTVA 107

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 767957741 188 AIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PRK11730 108 AINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPG 147
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 98-228 3.51e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 81.45  E-value: 3.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKmSSSEVGPFVSKIRAVIND 177
Cdd:PRK06688  14 GVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTG-AGRAFSAGGDIKDFPK-APPKPPDELAPVNRFLRA 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767957741 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:PRK06688  92 IAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDA 142
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 98-227 1.26e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 79.68  E-value: 1.26e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGkNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvpG-IFCAGADLKE-RAKMSSSEVGPFVSKIRAVI 175
Cdd:PRK07658  11 HVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGE--GrFFSAGADIKEfTSVTEAEQATELAQLGQVTF 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 767957741 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PRK07658  88 ERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPG 139
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 99-228 1.92e-16

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 76.24  E-value: 1.92e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741   99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLL 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 767957741  179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:pfam00378  85 YTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGA 134
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
99-227 4.50e-14

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 70.16  E-value: 4.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK05809  14 IAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNKVFRKL 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 767957741 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PRK05809  94 ENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPG 142
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
93-226 8.16e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 69.32  E-value: 8.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  93 AADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLK-ERAKMSSSEVGPFVS-- 169
Cdd:PRK07468   9 AVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKS-FCAGGDLGwMRAQMTADRATRIEEar 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767957741 170 KIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PRK07468  88 RLAMMLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIP 144
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 99-224 8.21e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 69.29  E-value: 8.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK06143  17 VATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISRLRDLCDAV 96

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 767957741 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAI 224
Cdd:PRK06143  97 RHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI 142
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 99-227 2.99e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 64.69  E-value: 2.99e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIII--RSEVpgiFCAGADLKERAKMSSSEVgpFVSKIRAVIN 176
Cdd:PRK08138  18 VALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLtgGEKV---FAAGADIKEFATAGAIEM--YLRHTERYWE 92

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767957741 177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PRK08138  93 AIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPG 143
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
99-228 3.97e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 64.35  E-value: 3.97e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIrSEVPGIFCAGADLKERAKMSSSEV---GPF-VSKIRAV 174
Cdd:PRK07799  15 TLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKAATKKPPGDSfkdGSYdPSRIDAL 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767957741 175 INDiANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:PRK07799  94 LKG-RRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMG 146
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 104-231 4.58e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 64.18  E-value: 4.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 104 INRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADL---KERAKMSSSEVGPFVSKIRAVINDIAN 180
Cdd:PRK05995  19 LNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKA-FCAGADLnwmKKMAGYSDDENRADARRLADMLRAIYR 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767957741 181 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGVTS 231
Cdd:PRK05995  98 CPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISP 148
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
99-227 8.73e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 63.45  E-value: 8.73e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKN-LIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKE-RAKMSSSEVGPFVSK------ 170
Cdd:PRK09245  13 IVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAGT-AFSSGGNVKDmRARVGAFGGSPADIRqgyrhg 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767957741 171 IRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PRK09245  92 IQRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPG 148
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 98-228 1.01e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 63.21  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSEVGPFVSKIRAVIND 177
Cdd:PRK05870  12 GVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKA-FCAGADLTALGAAPGRPAEDGLRRIYDGFLA 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767957741 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:PRK05870  91 VASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGG 141
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 94-227 1.13e-11

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 63.25  E-value: 1.13e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  94 ADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSssevgpfvskIRA 173
Cdd:PRK09674   7 SRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGN-ARFFAAGADLNEMAEKD----------LAA 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767957741 174 VIND--------IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PRK09674  76 TLNDprpqlwqrLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPG 137
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 99-214 1.95e-11

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 62.65  E-value: 1.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIND 177
Cdd:PRK08139  21 VATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKEmRAARGLAYFRALFARCSRVMQA 99

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 767957741 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK 214
Cdd:PRK08139 100 IVALPQPVIARVHGIATAAGCQLVASCDLAVAADTAR 136
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 98-227 4.34e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 61.60  E-value: 4.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIR-SEvpGIFCAGADLKERAKMSSSEVgpFVSKIRAVIN 176
Cdd:PRK05862  13 RVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITgSE--KAFAAGADIKEMADLSFMDV--YKGDYITNWE 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767957741 177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPG 227
Cdd:PRK05862  89 KVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPG 139
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
98-226 7.51e-11

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 60.85  E-value: 7.51e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIrSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVIN- 176
Cdd:PRK07827  15 GVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVL-THTGGTFCAGADLSEAGGGGGDPYDAAVARAREMTAl 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 767957741 177 --DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PRK07827  94 lrAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAP 145
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
104-226 2.91e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 59.12  E-value: 2.91e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 104 INRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSSEVGpfvsKIRAVINDIAN--- 180
Cdd:PRK07509  18 LNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGE-GGAFCAGLDVKSVASSPGNAVK----LLFKRLPGNANlaq 92

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767957741 181 --------LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PRK07509  93 rvslgwrrLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVP 146
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 94-228 2.21e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 56.52  E-value: 2.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  94 ADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERAKMSSSEVGPFVSK--I 171
Cdd:PRK06190   9 ETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADP-AFCAGLDLKELGGDGSAYGAQDALPnpS 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767957741 172 RAVindiANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:PRK06190  88 PAW----PAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGW 140
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 105-216 6.24e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 55.38  E-value: 6.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 105 NRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVG-PFVSKIRAVINDIANLPV 183
Cdd:PRK06144  24 NRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAvAYERRIDRVLGALEQLRV 103

                         90       100       110
                 ....*....|....*....|....*....|...
gi 767957741 184 PTIAAIDGLALGGGLELALACDIRVAASSAKMG 216
Cdd:PRK06144 104 PTIAAIAGACVGGGAAIAAACDLRIATPSARFG 136
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
98-228 7.04e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 55.02  E-value: 7.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDkkVRTIIIRSEVPGiFCAGADLKERAKMSSSEVGPFVSKIRAVIND 177
Cdd:PRK08150  11 GVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDH-FCAGLDLSELRERDAGEGMHHSRRWHRVFDK 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767957741 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:PRK08150  88 IQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGG 138
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 98-213 1.61e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 53.87  E-value: 1.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALkSDKKVRTIIIRSEVPgIFCAGADLKERAKMSSsevgpFVSKIRAVIND 177
Cdd:PRK07854   9 QVLTIELQRPERRNALNAELCEELREAVRKA-VDESARAIVLTGQGT-VFCAGADLSGDVYADD-----FPDALIEMLHA 81

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 767957741 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSA 213
Cdd:PRK07854  82 IDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEA 117
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
128-228 4.59e-08

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 53.75  E-value: 4.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 128 LKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKI-RAVINDIANLPVPTIAAIDGLALGGGLELALACDI 206
Cdd:PRK11154  46 LREDKELKGVVFISGKPDNFIAGADINMLAACKTAQEAEALARQgQQLFAEIEALPIPVVAAIHGACLGGGLELALACHY 125

                         90       100
                 ....*....|....*....|....
gi 767957741 207 RVAASSAK--MGLVETKLAIIPGG 228
Cdd:PRK11154 126 RVCTDDPKtvLGLPEVQLGLLPGS 149
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
111-228 5.60e-08

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 52.39  E-value: 5.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSSEvGPFVS---KIRAVINDIANLPVPTIA 187
Cdd:PRK06495  25 NALSRELRDELIAVFDEISERPDVRVVVLTGA-GKVFCAGADLKGRPDVIKGP-GDLRAhnrRTRECFHAIRECAKPVIA 102

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 767957741 188 AIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:PRK06495 103 AVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLAGGG 143
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 99-228 6.76e-08

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 52.92  E-value: 6.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741   99 IVVLGINRAYGK-NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIN 176
Cdd:TIGR02441  23 VAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMiAACKTAQEVTQLSQEGQEMFE 102

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 767957741  177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGG 228
Cdd:TIGR02441 103 RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGA 156
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 101-232 8.79e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 51.92  E-value: 8.79e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 101 VLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLK---ERAKMSSSEVGPFVSKIRAVIND 177
Cdd:PRK07511  15 VLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGA-GGFFCAGGNLNrllENRAKPPSVQAASIDGLHDWIRA 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767957741 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP-GGVTSS 232
Cdd:PRK07511  94 IRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPdGGGSWF 149
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 98-224 3.02e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 50.47  E-value: 3.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSE--VGPFVSKIRAVI 175
Cdd:PRK06127  20 GLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAeaVAAYEQAVEAAQ 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 767957741 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAI 224
Cdd:PRK06127 100 AALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGL 148
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
73-228 3.18e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 49.99  E-value: 3.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  73 TEDELRVrhleeENRDsssmaadhyRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIrSEVPGIFCAGAD 152
Cdd:PRK08252   1 MSDEVLV-----ERRG---------RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGIL-TGAGGTFCAGMD 65

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767957741 153 LKERAKmsssevGPFVSKIRAVINDIANLPV--PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228
Cdd:PRK08252  66 LKAFAR------GERPSIPGRGFGGLTERPPrkPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAG 137
PLN02888 PLN02888
enoyl-CoA hydratase
 99-226 4.32e-07

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 49.75  E-value: 4.32e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKerakmSSSEVGPFVSKIRAvINDI 178
Cdd:PLN02888  20 IATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRA-FCSGVDLT-----AAEEVFKGDVKDVE-TDPV 92

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767957741 179 ANLP---VPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PLN02888  93 AQMErcrKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFP 143
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
98-226 5.38e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 49.37  E-value: 5.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKE----RAKMSSSEVGPFVSKIRA 173
Cdd:PRK05980  12 GIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEfsasVAAGADVALRDFVRRGQA 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767957741 174 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PRK05980  92 MTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPP 144
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 94-214 1.44e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 48.16  E-value: 1.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  94 ADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKE------RAKMSSSEVGPF 167
Cdd:PRK06210  11 VADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGADMGElqtidpSDGRRDTDVRPF 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767957741 168 VSKIRAVIND----IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK 214
Cdd:PRK06210  90 VGNRRPDYQTryhfLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAK 140
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 121-226 2.32e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 47.61  E-value: 2.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 121 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKErakmsssevgpFVSKIRAVINDIA-----------NLPVPTIAAI 189
Cdd:PRK09076  34 LKQLVLELNADKDVYALVITGDGEKFFSAGADLNL-----------FADGDKAVAREMArrfgeafealsAFRGVSIAAI 102

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 767957741 190 DGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PRK09076 103 NGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLP 139
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 111-241 2.35e-06

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 47.14  E-value: 2.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAID 190
Cdd:PRK05869  29 NALTRQVYREIVAAANELGRRDDVAAVILYGG-HEIFSAGDDMPELRTLSAQEADTAARVRQQAVDAVAAIPKPTVAAIT 107

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767957741 191 GLALGGGLELALACDIRVAASSAKMGLVETKLAIIP--GGVTSSTEVLNPSKS 241
Cdd:PRK05869 108 GYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPsgDGMARLTRAAGPSRA 160
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 102-226 2.46e-06

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 47.50  E-value: 2.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 102 LGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADL---KERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK05674  19 LWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRH-FSAGADLawmQQSADLDYNTNLDDARELAELMYNL 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 767957741 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PRK05674  98 YRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAP 145
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 98-224 5.32e-06

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 46.56  E-value: 5.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKkVRTIIIRSEVPG-IFCAGADLKE-----RAKMSSSEvgPFVSKI 171
Cdd:PRK11423  13 KIATITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHElpsggRDPLSYDD--PLRQIL 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767957741 172 RAvindIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAI 224
Cdd:PRK11423  90 RM----IQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGV 138
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 98-243 8.91e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 45.80  E-value: 8.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGP--FVSkiravI 175
Cdd:PRK06494  13 HVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKRGWPEsgFGG-----L 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP--GGVTSSTEVLnPSKSSM 243
Cdd:PRK06494  88 TSRFDLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAAlaGGLHRLPRQI-GLKRAM 156
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 95-214 1.65e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 45.15  E-value: 1.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  95 DHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLkerakmsSSEVGPFVSKIRA- 173
Cdd:PRK06072   6 SREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRA-FCVGADL-------SEFAPDFAIDLREt 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 767957741 174 ---VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK 214
Cdd:PRK06072  78 fypIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVK 121
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 99-225 2.07e-05

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 44.89  E-value: 2.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVrTIIIRSEVPGIFCAGADLKERAKMS----SSEVGPFVSKIR-- 172
Cdd:PLN02664  18 VFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNV-SVIILSGAGDHFCSGIDLKTLNSISeqssSGDRGRSGERLRrk 96

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767957741 173 -----AVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAII 225
Cdd:PLN02664  97 ikflqDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAIT 154
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 111-190 3.62e-05

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 44.38  E-value: 3.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKM----SSSEVGPFVSKIRAVINDIANLPVPTI 186
Cdd:pfam16113  13 NALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAakagGGEAGRDFFREEYRLNYLIATYPKPYV 92


                  ....
gi 767957741  187 AAID 190
Cdd:pfam16113  93 ALMD 96
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 95-232 4.93e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 43.67  E-value: 4.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  95 DHYR--IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSE-VGPFVSKI 171
Cdd:PRK05864  14 DHPRpeIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSSGADHKSAGVVPHVEgLTRPTYAL 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767957741 172 RA------VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMglvetKLAIIPGGVTSS 232
Cdd:PRK05864  93 RSmellddVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYF-----RAAGINNGLTAS 154
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 94-218 5.26e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 43.36  E-value: 5.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  94 ADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKsDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSEV--------- 164
Cdd:PRK08140   9 AIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAGRG-FCAGQDLADRDVTPGGAMpdlgesiet 86

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767957741 165 --GPFVSKIRAvindianLPVPTIAAIDGLALGGGLELALACDIRVAASSA-------KMGLV 218
Cdd:PRK08140  87 fyNPLVRRLRA-------LPLPVIAAVNGVAAGAGANLALACDIVLAARSAsfiqafvKIGLV 142
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 99-226 1.20e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 42.69  E-value: 1.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIirseVPG---IFCAGADL---------KERAKMSSS---- 162
Cdd:PRK08260  14 IATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVI----VTGagrAFCAGADLsaggntfdlDAPRTPVEAdeed 89

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767957741 163 EVGPFVSKIR----AVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PRK08260  90 RADPSDDGVRdgggRVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVP 157
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
111-218 1.60e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 42.03  E-value: 1.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 111 NSLSKNLIKMLSKAVDALKSDK-KVRTIIIRSEVPGiFCAGADLKER---AKMSSSEVG----------PFVSKIRavin 176
Cdd:PRK05981  26 NAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAGRG-FCTGANLQGRgsgGRESDSGGDagaaletayhPFLRRLR---- 100

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 767957741 177 diaNLPVPTIAAIDGLALGGGLELALACDIRVAASSA-------KMGLV 218
Cdd:PRK05981 101 ---NLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAyflqafrRIGLV 146
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
98-221 2.00e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 41.88  E-value: 2.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKE----RAKMSSSEVGPFVSKIRA 173
Cdd:PRK08258  26 GVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGN-FCSGGDVHEiigpLTKMDMPELLAFTRMTGD 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 767957741 174 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETK 221
Cdd:PRK08258 105 LVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTR 152
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
121-219 2.56e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 41.50  E-value: 2.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 121 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSEV------GPFVSkIRAVINDianlPVPTIAAIDGLAL 194
Cdd:PRK07938  33 LADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQATPGFTAlidanrGCFAA-FRAVYEC----AVPVIAAVHGFCL 106

                         90       100
                 ....*....|....*....|....*
gi 767957741 195 GGGLELALACDIRVAASSAKMGLVE 219
Cdd:PRK07938 107 GGGIGLVGNADVIVASDDATFGLPE 131
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 98-154 3.08e-04

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 41.34  E-value: 3.08e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767957741  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLK 154
Cdd:PRK05617  12 GVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIR 68
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 111-224 4.44e-04

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 40.63  E-value: 4.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEV-PGIFCAGADLKE--RAKMSSSEVGPFVSKIRAVINDIANLPVPTIA 187
Cdd:PLN03214  33 NSMTLAMWRSLDDALTALENDPTVRGVVFASGLrRDVFTAGNDIAElyAPKTSAARYAEFWLTQTTFLVRLLRSRLATVC 112

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 767957741 188 AIDGLALGGGLELALACDIRVAASSAKMGLVETKLAI 224
Cdd:PLN03214 113 AIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGI 149
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
94-225 1.17e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 39.57  E-value: 1.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  94 ADHyrIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERA-----KMSSSEVGP-- 166
Cdd:PRK06142  13 ADH--VAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLPAMAgvfgqLGKDGLARPrt 89

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767957741 167 -FVSKIR---AVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAII 225
Cdd:PRK06142  90 dLRREILrlqAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMV 152
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
 109-189 1.21e-03

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 39.31  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 109 GKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLK--ERAKMSSSEVGPFVSKIRAVINDIANLPVPTI 186
Cdd:PLN02267  19 GEHRLNPTLIDSIRSALRQVKSQATPGSVLITTAEGKFFSNGFDLAwaQAAGSAPSRLHLMVAKLRPLVADLISLPMPTI 98


                 ...
gi 767957741 187 AAI 189
Cdd:PLN02267  99 AAV 101
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
99-230 1.24e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 39.17  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERA--------KMSSSEVGPF--- 167
Cdd:PRK06563   9 VLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEH-FTAGLDLADVApklaaggfPFPEGGIDPWgtv 87

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767957741 168 ---VSKiravindianlpvPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIP-GGVT 230
Cdd:PRK06563  88 grrLSK-------------PLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPfGGAT 141
PLN02921 PLN02921
naphthoate synthase
 104-233 1.59e-03

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 39.39  E-value: 1.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 104 INRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKmsSSEVGPFVSKIRAVIN---DIAN 180
Cdd:PLN02921  82 INRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGK--DGYVGPDDAGRLNVLDlqiQIRR 159

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767957741 181 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGVTSST 233
Cdd:PLN02921 160 LPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSI 212
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 105-231 1.71e-03

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 38.84  E-value: 1.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 105 NRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKE--RAKMSSSEVGpfVSKIRAVIND----I 178
Cdd:PRK09120  24 NRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDA-WSAGMDLKEyfRETDAQPEIL--QERIRREAYGwwrrL 100

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767957741 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGVTS 231
Cdd:PRK09120 101 RWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVS 153
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
127-226 4.78e-03

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 37.75  E-value: 4.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741 127 ALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSE----VGPFvskirAVINDIANLPVPTIAAIDGLALGGGLELAL 202
Cdd:PRK03580  40 NFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDadfgPGGF-----AGLTEIFDLDKPVIAAVNGYAFGGGFELAL 114

                         90       100
                 ....*....|....*....|....
gi 767957741 203 ACDIRVAASSAKMGLVETKLAIIP 226
Cdd:PRK03580 115 AADFIVCADNASFALPEAKLGIVP 138
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 99-229 5.45e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 37.41  E-value: 5.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957741  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK07260  12 LATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELVNEI 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767957741 179 A----NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKM--GLVETKLAIIPGGV 229
Cdd:PRK07260  91 SfaikQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFiqAFVGVGLAPDAGGL 147
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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