NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|767983700|ref|XP_011519695|]
View 

major intrinsically disordered Notch2-binding receptor 1 isoform X1 [Homo sapiens]

Protein Classification

major intrinsically disordered Notch2-associated receptor 1( domain architecture ID 10536075)

major intrinsically disordered Notch2-associated receptor 1 (MINAR1) is a Notch2-binding protein that inhibits angiogenesis and breast cancer growth

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
MINAR1_C pfam06789
MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) ...
759-911 1.55e-67

MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) is a Notch2-binding protein that has been shown to inhibit angiogenesis and breast cancer growth. This entry represents the C terminus of the MINAR1 protein.


:

Pssm-ID: 462010  Cd Length: 148  Bit Score: 221.62  E-value: 1.55e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767983700  759 DWHRK---SKEADRQYDIPPQHRLPKQPKdgFLVEQVFSPHPYPASLKAHMKSNPLYTDMRLTELAEVKRGQPSWTIEEY 835
Cdd:pfam06789   1 QWHNRvysQKEKKRQYDQPTVHLSEKSPK--VLVDKVLSKHITPVTLKSHIKRNPLYTDLRIVDTWEEKRPQPSWTIQEY 78
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767983700  836 ARNA--GDKGKLTaldlqtqeSLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPI 911
Cdd:pfam06789  79 DRHSlhGNLAKYL--------KENPNNLEYWLEDIYTPGYDSLLKRKEAEFKRSKLCKIILLIVLLICIVILVIIVPI 148
 
Name Accession Description Interval E-value
MINAR1_C pfam06789
MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) ...
759-911 1.55e-67

MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) is a Notch2-binding protein that has been shown to inhibit angiogenesis and breast cancer growth. This entry represents the C terminus of the MINAR1 protein.


Pssm-ID: 462010  Cd Length: 148  Bit Score: 221.62  E-value: 1.55e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767983700  759 DWHRK---SKEADRQYDIPPQHRLPKQPKdgFLVEQVFSPHPYPASLKAHMKSNPLYTDMRLTELAEVKRGQPSWTIEEY 835
Cdd:pfam06789   1 QWHNRvysQKEKKRQYDQPTVHLSEKSPK--VLVDKVLSKHITPVTLKSHIKRNPLYTDLRIVDTWEEKRPQPSWTIQEY 78
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767983700  836 ARNA--GDKGKLTaldlqtqeSLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPI 911
Cdd:pfam06789  79 DRHSlhGNLAKYL--------KENPNNLEYWLEDIYTPGYDSLLKRKEAEFKRSKLCKIILLIVLLICIVILVIIVPI 148
 
Name Accession Description Interval E-value
MINAR1_C pfam06789
MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) ...
759-911 1.55e-67

MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) is a Notch2-binding protein that has been shown to inhibit angiogenesis and breast cancer growth. This entry represents the C terminus of the MINAR1 protein.


Pssm-ID: 462010  Cd Length: 148  Bit Score: 221.62  E-value: 1.55e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767983700  759 DWHRK---SKEADRQYDIPPQHRLPKQPKdgFLVEQVFSPHPYPASLKAHMKSNPLYTDMRLTELAEVKRGQPSWTIEEY 835
Cdd:pfam06789   1 QWHNRvysQKEKKRQYDQPTVHLSEKSPK--VLVDKVLSKHITPVTLKSHIKRNPLYTDLRIVDTWEEKRPQPSWTIQEY 78
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767983700  836 ARNA--GDKGKLTaldlqtqeSLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPI 911
Cdd:pfam06789  79 DRHSlhGNLAKYL--------KENPNNLEYWLEDIYTPGYDSLLKRKEAEFKRSKLCKIILLIVLLICIVILVIIVPI 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH