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Conserved domains on  [gi|767984892|ref|XP_011520161|]
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DNA repair protein RAD51 homolog 1 isoform X2 [Homo sapiens]

Protein Classification

RAD51 family DNA repair protein( domain architecture ID 11494003)

DNA repair protein RAD51 is required both for recombination and for the repair of DNA damage caused by X-rays

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
recomb_RAD51 TIGR02239
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ...
25-339 0e+00

DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).


:

Pssm-ID: 274048 [Multi-domain]  Cd Length: 316  Bit Score: 661.81  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   25 ISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITT 104
Cdd:TIGR02239   1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  105 GSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSD 184
Cdd:TIGR02239  81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLNPED 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  185 VLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVV 264
Cdd:TIGR02239 161 VLDNVAYARAYNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGVAVV 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767984892  265 ITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 339
Cdd:TIGR02239 241 ITNQVVAQVDGAGsMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
 
Name Accession Description Interval E-value
recomb_RAD51 TIGR02239
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ...
25-339 0e+00

DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).


Pssm-ID: 274048 [Multi-domain]  Cd Length: 316  Bit Score: 661.81  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   25 ISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITT 104
Cdd:TIGR02239   1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  105 GSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSD 184
Cdd:TIGR02239  81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLNPED 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  185 VLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVV 264
Cdd:TIGR02239 161 VLDNVAYARAYNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGVAVV 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767984892  265 ITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 339
Cdd:TIGR02239 241 ITNQVVAQVDGAGsMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
PTZ00035 PTZ00035
Rad51 protein; Provisional
4-339 0e+00

Rad51 protein; Provisional


Pssm-ID: 185407 [Multi-domain]  Cd Length: 337  Bit Score: 623.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   4 QMQLEANADTSVEEESfGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVP 83
Cdd:PTZ00035   3 ESQNEQQEEEEEEEAE-GFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLVP 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  84 MGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTE 163
Cdd:PTZ00035  82 MGFISATEYLEARKNIIRITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTE 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 164 GTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQM 243
Cdd:PTZ00035 162 GTFRPERIVQIAERFGLDPEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEERFALLIVDSATALFRVDYSGRGELAERQQ 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 244 HLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEA 323
Cdd:PTZ00035 242 HLGKFLRALQKLADEFNVAVVITNQVMADVDGASMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSPNLPES 321
                        330
                 ....*....|....*.
gi 767984892 324 EAMFAINADGVGDAKD 339
Cdd:PTZ00035 322 EAVFAISEGGIIDAKD 337
Rad51 cd19513
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ...
102-336 0e+00

RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.


Pssm-ID: 410921 [Multi-domain]  Cd Length: 235  Bit Score: 555.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLS 181
Cdd:cd19513    1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 182 GSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGV 261
Cdd:cd19513   81 GEDVLDNVAYARAYNTDHQMQLLIQASAMMAESRYALLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767984892 262 AVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 336
Cdd:cd19513  161 AVVITNQVVAQVDGAAMFAGDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITEDGIGD 235
Rad51 pfam08423
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ...
84-337 0e+00

Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.


Pssm-ID: 462471 [Multi-domain]  Cd Length: 255  Bit Score: 527.64  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   84 MGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTE 163
Cdd:pfam08423   1 MGFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  164 GTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQM 243
Cdd:pfam08423  81 GTFRPERLVAIAERYGLDPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELAERQQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  244 HLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPE 322
Cdd:pfam08423 161 HLAKFLRTLQRLADEFGVAVVITNQVVAQVDGAAgMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSPCLPE 240
                         250
                  ....*....|....*
gi 767984892  323 AEAMFAINADGVGDA 337
Cdd:pfam08423 241 SEAVFAIGSGGIIDP 255
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
94-305 5.79e-24

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 100.63  E-value: 5.79e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  94 QRRSEIIQITTGSKELDKLL-QGGIETGSITEMFGEFRTGKTQICHTLAVTCQLpidRGGGegkAMYIDTEGTFRPERll 172
Cdd:COG0468   36 KARQDVEVISTGSLALDIALgVGGLPRGRIVEIYGPESSGKTTLALHAIAEAQK---AGGI---AAFIDAEHALDPEY-- 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 173 avAERYGLSgsdvLDNVAYARAFNTDHQTQLLyqasAMMVESRYALLIV-DSATALY-RTDYSGR-GE----LSARQMHL 245
Cdd:COG0468  108 --AKKLGVD----IDNLLVSQPDTGEQALEIA----ETLVRSGAVDLIVvDSVAALVpKAEIEGEmGDshvgLQARLMSQ 177
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 246 ArfLRMLLRLADEFGVAVVITNQVVAQVDgaAMFaADPKKPIGGNIIAHASTTRLYLRKG 305
Cdd:COG0468  178 A--LRKLTGAISKSNTTVIFINQLREKIG--VMF-GNPETTTGGNALKFYASVRLDIRRI 232
 
Name Accession Description Interval E-value
recomb_RAD51 TIGR02239
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ...
25-339 0e+00

DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).


Pssm-ID: 274048 [Multi-domain]  Cd Length: 316  Bit Score: 661.81  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   25 ISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITT 104
Cdd:TIGR02239   1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  105 GSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSD 184
Cdd:TIGR02239  81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLNPED 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  185 VLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVV 264
Cdd:TIGR02239 161 VLDNVAYARAYNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGVAVV 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767984892  265 ITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 339
Cdd:TIGR02239 241 ITNQVVAQVDGAGsMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
PTZ00035 PTZ00035
Rad51 protein; Provisional
4-339 0e+00

Rad51 protein; Provisional


Pssm-ID: 185407 [Multi-domain]  Cd Length: 337  Bit Score: 623.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   4 QMQLEANADTSVEEESfGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVP 83
Cdd:PTZ00035   3 ESQNEQQEEEEEEEAE-GFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLVP 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  84 MGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTE 163
Cdd:PTZ00035  82 MGFISATEYLEARKNIIRITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTE 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 164 GTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQM 243
Cdd:PTZ00035 162 GTFRPERIVQIAERFGLDPEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEERFALLIVDSATALFRVDYSGRGELAERQQ 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 244 HLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEA 323
Cdd:PTZ00035 242 HLGKFLRALQKLADEFNVAVVITNQVMADVDGASMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSPNLPES 321
                        330
                 ....*....|....*.
gi 767984892 324 EAMFAINADGVGDAKD 339
Cdd:PTZ00035 322 EAVFAISEGGIIDAKD 337
PLN03186 PLN03186
DNA repair protein RAD51 homolog; Provisional
1-339 0e+00

DNA repair protein RAD51 homolog; Provisional


Pssm-ID: 178728 [Multi-domain]  Cd Length: 342  Bit Score: 611.74  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   1 MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAK 80
Cdd:PLN03186   4 AVAAAAAQAMQEEEEEEAAHGPFPIEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  81 LVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYI 160
Cdd:PLN03186  84 LVPLGFTTASQLHAQRQEIIQITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 161 DTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSA 240
Cdd:PLN03186 164 DTEGTFRPQRLIQIAERFGLNGADVLENVAYARAYNTDHQSELLLEAASMMAETRFALMIVDSATALYRTEFSGRGELSA 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 241 RQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCL 320
Cdd:PLN03186 244 RQMHLGKFLRSLQRLADEFGVAVVITNQVVAQVDGSAFFAGPQLKPIGGNIMAHASTTRLALRKGRGENRICKVISSPCL 323
                        330
                 ....*....|....*....
gi 767984892 321 PEAEAMFAINADGVGDAKD 339
Cdd:PLN03186 324 PEAEARFSISSEGVTDVKD 342
Rad51 cd19513
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ...
102-336 0e+00

RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.


Pssm-ID: 410921 [Multi-domain]  Cd Length: 235  Bit Score: 555.39  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLS 181
Cdd:cd19513    1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 182 GSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGV 261
Cdd:cd19513   81 GEDVLDNVAYARAYNTDHQMQLLIQASAMMAESRYALLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767984892 262 AVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 336
Cdd:cd19513  161 AVVITNQVVAQVDGAAMFAGDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITEDGIGD 235
Rad51 pfam08423
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ...
84-337 0e+00

Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.


Pssm-ID: 462471 [Multi-domain]  Cd Length: 255  Bit Score: 527.64  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   84 MGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTE 163
Cdd:pfam08423   1 MGFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  164 GTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQM 243
Cdd:pfam08423  81 GTFRPERLVAIAERYGLDPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELAERQQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  244 HLARFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPE 322
Cdd:pfam08423 161 HLAKFLRTLQRLADEFGVAVVITNQVVAQVDGAAgMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSPCLPE 240
                         250
                  ....*....|....*
gi 767984892  323 AEAMFAINADGVGDA 337
Cdd:pfam08423 241 SEAVFAIGSGGIIDP 255
Rad51_DMC1_archRadA cd01123
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ...
102-335 8.92e-167

recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .


Pssm-ID: 410868 [Multi-domain]  Cd Length: 234  Bit Score: 463.93  E-value: 8.92e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLS 181
Cdd:cd01123    1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIAQRFGLD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 182 GSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGV 261
Cdd:cd01123   81 PDDVLDNVAYARAFNSDHQTQLLDQAAAMMVESRFKLLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767984892 262 AVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVG 335
Cdd:cd01123  161 AVVVTNQVVAQVDGAMMFAADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITADGVG 234
PLN03187 PLN03187
meiotic recombination protein DMC1 homolog; Provisional
4-339 5.67e-154

meiotic recombination protein DMC1 homolog; Provisional


Pssm-ID: 215620 [Multi-domain]  Cd Length: 344  Bit Score: 435.75  E-value: 5.67e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   4 QMQLEANADTSVEEESFgpQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVP 83
Cdd:PLN03187  12 QLQLVEAEEVDEEEDLF--ESIDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKLLN 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  84 MGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTE 163
Cdd:PLN03187  90 QGFITGSDALLKRKSVVRITTGSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 164 GTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQM 243
Cdd:PLN03187 170 GTFRPDRIVPIAERFGMDADAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFTGRGELAERQQ 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 244 HLARFLRMLLRLADEFGVAVVITNQVVAQvDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEA 323
Cdd:PLN03187 250 KLAQMLSRLTKIAEEFNVAVYMTNQVIAD-PGGGMFISDPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKVFDAPNLPEA 328
                        330
                 ....*....|....*.
gi 767984892 324 EAMFAINADGVGDAKD 339
Cdd:PLN03187 329 EAEFQITSGGIMDAKD 344
recomb_DMC1 TIGR02238
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ...
25-337 6.52e-152

meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.


Pssm-ID: 131292 [Multi-domain]  Cd Length: 313  Bit Score: 429.20  E-value: 6.52e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   25 ISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITT 104
Cdd:TIGR02238   1 IDKLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKIINPGFITAFEISQKRKKVLKITT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  105 GSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSD 184
Cdd:TIGR02238  81 GSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAIAERFGVDPDA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  185 VLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVV 264
Cdd:TIGR02238 161 VLDNILYARAYTSEHQMELLDYLAAKFSEEPFRLLIVDSIMALFRVDFSGRGELSERQQKLAQMLSRLNKISEEFNVAVF 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767984892  265 ITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDA 337
Cdd:TIGR02238 241 VTNQVQADPGATMTFIADPKKPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEAEASFQITEGGIADA 313
DMC1 cd19514
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ...
102-336 2.37e-138

homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.


Pssm-ID: 410922 [Multi-domain]  Cd Length: 236  Bit Score: 391.72  E-value: 2.37e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLS 181
Cdd:cd19514    1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPIAERFGVD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 182 GSDVLDNVAYARAFNTDHQTQLLYQASAMMVES-RYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFG 260
Cdd:cd19514   81 HDAVLDNILYARAYTSEHQMELLDYVAAKFHEEaVFRLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYN 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767984892 261 VAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 336
Cdd:cd19514  161 VAVFITNQVTADPGAAMTFQADPKKPIGGHILAHASTTRISLRKGRGEERIAKIYDSPDLPENEATFAITAGGIAD 236
radA PRK04301
DNA repair and recombination protein RadA; Validated
32-337 2.96e-136

DNA repair and recombination protein RadA; Validated


Pssm-ID: 235273 [Multi-domain]  Cd Length: 317  Bit Score: 389.62  E-value: 2.96e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  32 GINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPM-GFTTATEFHQRRSEIIQITTGSKELD 110
Cdd:PRK04301  13 GVGPATAEKLREAGYDTVEAIAVASPKELSEAAGIGESTAAKIIEAAREAADIgGFETALEVLERRKNVGKITTGSKELD 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 111 KLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVA 190
Cdd:PRK04301  93 ELLGGGIETQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRPERIEQMAEALGLDPDEVLDNIH 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 191 YARAFNTDHQTQLLYQASAMMVESR-YALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQV 269
Cdd:PRK04301 173 VARAYNSDHQMLLAEKAEELIKEGEnIKLVIVDSLTAHFRAEYVGRGNLAERQQKLNKHLHDLLRLADLYNAAVVVTNQV 252
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767984892 270 VAQVDgaaMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDA 337
Cdd:PRK04301 253 MARPD---AFFGDPTQPIGGHILGHTATFRIYLRKSKGNKRIARLVDSPHLPEGEAVFRITEEGIRDA 317
recomb_radA TIGR02236
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ...
32-336 2.53e-121

DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 131290 [Multi-domain]  Cd Length: 310  Bit Score: 351.74  E-value: 2.53e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   32 GINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMG-FTTATEFHQRRSEIIQITTGSKELD 110
Cdd:TIGR02236   6 GVGPATAEKLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAADLGgFETADDVLERRKTIGKITTGSKELD 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  111 KLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVA 190
Cdd:TIGR02236  86 ELLGGGIETQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQMAEARGLDPDEVLKNIY 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  191 YARAFNTDHQTQLLYQASAMMVE--SRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQ 268
Cdd:TIGR02236 166 VARAYNSNHQMLLVEKAEDLIKElnNPVKLLIVDSLTSHFRAEYVGRGALAERQQKLNKHLHDLLRLADLYNAAVVVTNQ 245
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767984892  269 VVAQVDgaaMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 336
Cdd:TIGR02236 246 VMARPD---AFFGDPTRPIGGHILGHAATFRVYLRKGKGDKRIARLVDSPHLPEGEAVFRITEKGIED 310
archRadA cd19515
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ...
102-336 1.02e-115

archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)


Pssm-ID: 410923 [Multi-domain]  Cd Length: 233  Bit Score: 334.33  E-value: 1.02e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLS 181
Cdd:cd19515    1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQMAKALGLD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 182 GSDVLDNVAYARAFNTDHQTQLLYQASAMMVESR-YALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFG 260
Cdd:cd19515   81 PDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNnIKLLIVDSLTSHFRAEYVGRGTLAERQQKLNKHLHDLHRLADLYN 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767984892 261 VAVVITNQVVAQVDgaaMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 336
Cdd:cd19515  161 IAVLVTNQVMAKPD---AFFGDPTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDSPHLPEGEAVFRITEKGIED 233
RecA-like cd01393
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
120-304 6.20e-50

RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.


Pssm-ID: 410881 [Multi-domain]  Cd Length: 185  Bit Score: 164.83  E-value: 6.20e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 120 GSITEMFGEFRTGKTQICHTLAVTCQLpidrggGEGKAMYIDTEGTFRPERLLAVAERYGLSGSD---VLDNVAYARAFN 196
Cdd:cd01393    1 GKITEIYGPPGSGKTQLALQLAANALL------LGGGVVWIDTEGAFPPSRLVQILEASPSSELElaeALSRLLYFRPPD 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 197 TDHQTQLL-YQASAMMVESRYALLIVDSATALYRTDY----SGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVA 271
Cdd:cd01393   75 TLAHLLALdSLPESLFPPPNTSLVVVDSVSALFRKAFprggDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTT 154
                        170       180       190
                 ....*....|....*....|....*....|...
gi 767984892 272 QVDGaaMFAADPKKPIGGNIIAHASTTRLYLRK 304
Cdd:cd01393  155 KIRG--GSGASLVPPALGNTWEHSVSTRLLLYR 185
XRCC3 cd19491
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ...
109-321 5.89e-46

XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410899 [Multi-domain]  Cd Length: 250  Bit Score: 156.68  E-value: 5.89e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 109 LDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDV--- 185
Cdd:cd19491    1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQLASSLPKRYHLEkak 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 186 --LDNVAYARAFNTDHQTQLL-YQASAMMVESRYALLIVDSATALYRTDY-SGRGELSARQMHLARFLRMLLRLADEFGV 261
Cdd:cd19491   81 nfLDNIFVEHVADLETLEHCLnYQLPALLERGPIRLVVIDSIAALFRSEFdTSRSDLVERAKYLRRLADHLKRLADKYNL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 262 AVVITNQVVAQVD------------GAAMFAADPKKPIGGNII-------AHASTTRLYLRKGRGET----------RIC 312
Cdd:cd19491  161 AVVVVNQVTDRFDsssdasglgvldYLSQFSSFSGGVSGNRKVpalgltwANLVNTRLMLSRTPKRItdssaasisvRRL 240

                 ....*....
gi 767984892 313 KIYDSPCLP 321
Cdd:cd19491  241 EVVFSPHLP 249
radB PRK09361
DNA repair and recombination protein RadB; Provisional
102-334 1.17e-44

DNA repair and recombination protein RadB; Provisional


Pssm-ID: 236482 [Multi-domain]  Cd Length: 225  Bit Score: 152.32  E-value: 1.17e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCqlpIDRGggeGKAMYIDTEGtFRPERLLAVAeryGLS 181
Cdd:PRK09361   5 LPTGCKMLDELLGGGFERGTITQIYGPPGSGKTNICLQLAVEA---AKNG---KKVIYIDTEG-LSPERFKQIA---GED 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 182 GSDVLDNVAYARAFNTDHQTQLLyQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGV 261
Cdd:PRK09361  75 FEELLSNIIIFEPSSFEEQSEAI-RKAEKLAKENVGLIVLDSATSLYRLELEDEEDNSKLNRELGRQLTHLLKLARKHDL 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767984892 262 AVVITNQVVAQVDGAAMfaadpkKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAE-AMFAINADGV 334
Cdd:PRK09361 154 AVVITNQVYSDIDSDGL------RPLGGHTLEHWSKTILRLEKFRNGKRRATLEKHRSRPEGEsAEFRITDRGI 221
archRadB cd01394
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ...
102-334 2.59e-43

archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.


Pssm-ID: 410882 [Multi-domain]  Cd Length: 216  Bit Score: 148.62  E-value: 2.59e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQlpidRGGgeGKAMYIDTEGtFRPERLLAVAeryGLS 181
Cdd:cd01394    1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQLAVEAA----KQG--KKVVYIDTEG-LSPERFQQIA---GER 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 182 GSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARqmhLARFLRMLLRLADEFGV 261
Cdd:cd01394   71 FESIASNIIVFEPYSFDEQGVAIQEAEKLLKSDKVDLVVVDSATALYRLELGDDSEANRE---LSRQMSKLLSIARKYDI 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767984892 262 AVVITNQVVAQVDgaamfaADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAE-AMFAINADGV 334
Cdd:cd01394  148 PVVITNQVYSDID------DDRLKPVGGTLLEHWSKAIIRLEKSPPGLRRATLEKHRSRPEGQsAGFRITDRGI 215
Rad51B cd19493
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ...
110-318 9.37e-38

RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410901 [Multi-domain]  Cd Length: 222  Bit Score: 134.37  E-value: 9.37e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 110 DKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAER-----------Y 178
Cdd:cd19493    1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIAEArfpeafsgfmeE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 179 GLSGSDVLDNVAYARafnTDHQTQLLYQASAM---MVESRYALLIVDSATALYRTDYSG-RGELSARQMHLARFLRMLLR 254
Cdd:cd19493   81 NERAEEMLKRVAVVR---VTTLAQLLERLPNLeehILSSGVRLVVIDSIAALVRREFGGsDGEVTERHNALAREASSLKR 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767984892 255 LADEFGVAVVITNQVVAQVDGAAMFAADPKKPIgGNIIAHASTTRLYLRKGRG-ETRICKIYDSP 318
Cdd:cd19493  158 LAEEFRIAVLVTNQATTHFGDAGDGSSGVTAAL-GDAWAHAVNTRLRLERCLLqLRRVLEIVKSP 221
recomb_radB TIGR02237
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ...
109-334 3.04e-37

DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).


Pssm-ID: 274047 [Multi-domain]  Cd Length: 209  Bit Score: 132.54  E-value: 3.04e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  109 LDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQlpidrgGGEGKAMYIDTEGtFRPERLLAVAERyglSGSDVLDN 188
Cdd:TIGR02237   1 IDELLGGGVERGTITQIYGPPGSGKTNICMILAVNAA------RQGKKVVYIDTEG-LSPERFKQIAED---RPERALSN 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  189 VAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSgrGELSARQMHLARFLRMLLRLADEFGVAVVITNQ 268
Cdd:TIGR02237  71 FIVFEVFDFDEQGVAIQKTSKFIDRDSASLVVVDSFTALYRLELS--DDRISRNRELARQLTLLLSLARKKNLAVVITNQ 148
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767984892  269 VVAQVDGaamfaaDPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGV 334
Cdd:TIGR02237 149 VYTDVNN------GTLRPLGGHLLEHWSKVILRLEKFRGRRLATLEKHRSRPEGESVYFRITDDGI 208
Rad51C cd19492
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ...
120-318 4.25e-32

RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.


Pssm-ID: 410900 [Multi-domain]  Cd Length: 172  Bit Score: 118.10  E-value: 4.25e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 120 GSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFrperllavaeryglsgsdvldNVAYARAFNTDH 199
Cdd:cd19492    1 GKITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF---------------------NIHYFRVHDYVE 59
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 200 QTQLLYQASAMMVE-SRYALLIVDSATALYRTDYSGrgeLSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQV--DGA 276
Cdd:cd19492   60 LLALINSLPKFLEDhPKVKLIVVDSIAFPFRHDFDD---LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKIseDGQ 136
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 767984892 277 AMFAadpkkPIGGNIIAHASTTRLYLRKGRGEtRICKIYDSP 318
Cdd:cd19492  137 SQLV-----PALGESWSHACTTRLFLTWDEKQ-RFAHLYKSP 172
Rad51D cd19489
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ...
114-304 3.14e-24

RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410897 [Multi-domain]  Cd Length: 209  Bit Score: 98.09  E-value: 3.14e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 114 QGGIETGSITEMFGEFRTGKTQICHTLA--VTCQLPIdrgggegKAMYIDTEGTFRPERLLAVAE-RYGLSGS--DVLDN 188
Cdd:cd19489    1 GGGLRTGEITELVGESSSGKTQLCLTAAanVASRSGQ-------NVLYIDTKSSFSARRLAQILKsRAQDAEEidKALQR 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 189 VAYARAFNTDHQTQLLYQASAMM------VESRYALLIVDSATAL---YRTDYS---GRGELsarqMHLARFLRmllRLA 256
Cdd:cd19489   74 IRVVRVFDPYELLDLLEELRNTLsqqqenLYSRLKLVIIDSLSALispLLGGSKhseGHALL----ASLARLLK---KLA 146
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 767984892 257 DEFGVAVVITNQVVaqVDGAAMFAADPkKPIGGNIIAHASTTRLYLRK 304
Cdd:cd19489  147 AEYQIAVLVTNLTV--RGGDGGQQGST-KPALGEYWESVPSTRLLLSR 191
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
94-305 5.79e-24

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 100.63  E-value: 5.79e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  94 QRRSEIIQITTGSKELDKLL-QGGIETGSITEMFGEFRTGKTQICHTLAVTCQLpidRGGGegkAMYIDTEGTFRPERll 172
Cdd:COG0468   36 KARQDVEVISTGSLALDIALgVGGLPRGRIVEIYGPESSGKTTLALHAIAEAQK---AGGI---AAFIDAEHALDPEY-- 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 173 avAERYGLSgsdvLDNVAYARAFNTDHQTQLLyqasAMMVESRYALLIV-DSATALY-RTDYSGR-GE----LSARQMHL 245
Cdd:COG0468  108 --AKKLGVD----IDNLLVSQPDTGEQALEIA----ETLVRSGAVDLIVvDSVAALVpKAEIEGEmGDshvgLQARLMSQ 177
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 246 ArfLRMLLRLADEFGVAVVITNQVVAQVDgaAMFaADPKKPIGGNIIAHASTTRLYLRKG 305
Cdd:COG0468  178 A--LRKLTGAISKSNTTVIFINQLREKIG--VMF-GNPETTTGGNALKFYASVRLDIRRI 232
XRCC2 cd19490
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ...
120-268 1.99e-14

XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.


Pssm-ID: 410898 [Multi-domain]  Cd Length: 226  Bit Score: 71.61  E-value: 1.99e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 120 GSITEMFGEFRTGKTQICHTLAVTCQLP-----IDRGGGEGKAMYIDTEGTFRPERLLAVAERY-------GLSGSDV-- 185
Cdd:cd19490    1 GDVIEITGPSGSGKTELLYHLAARCILPsswggVPLGGLEAAVVFIDTDGRFDILRLRSILEARiraaiqaANSSDDEed 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 186 --------LDNVAYARAFNTDHQTQLLYQASAMMVESRY----ALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLL 253
Cdd:cd19490   81 veeiarecLQRLHIFRCHSSLQLLATLLSLENYLLSLSAnpelGLLLIDSISAFYWQDRFSAELARAAPLLQEAALRAIL 160
                        170
                 ....*....|....*....
gi 767984892 254 ----RLADEFGVAVVITNQ 268
Cdd:cd19490  161 relrRLRRRFQLVVIATKQ 179
RAD55 COG0467
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
102-282 1.19e-11

RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];


Pssm-ID: 440235 [Multi-domain]  Cd Length: 221  Bit Score: 63.40  E-value: 1.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVtcqlpidRGGGEG-KAMYIDTEgtFRPERLLAVAERYGL 180
Cdd:COG0467    2 VPTGIPGLDELLGGGLPRGSSTLLSGPPGTGKTTLALQFLA-------EGLRRGeKGLYVSFE--ESPEQLLRRAESLGL 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 181 SGSDVLDN--VAYARAFNTDHQT---QLLYQASAMMVESRYALLIVDSATALYRtdysgrgeLSARQMHLARFLRMLLRL 255
Cdd:COG0467   73 DLEEYIESglLRIIDLSPEELGLdleELLARLREAVEEFGAKRVVIDSLSGLLL--------ALPDPERLREFLHRLLRY 144
                        170       180       190
                 ....*....|....*....|....*....|.
gi 767984892 256 ADEFGVAVVITNQV----VAQVDGAAMFAAD 282
Cdd:COG0467  145 LKKRGVTTLLTSETggleDEATEGGLSYLAD 175
RepA COG3598
RecA-family ATPase [Replication, recombination and repair];
112-310 2.75e-11

RecA-family ATPase [Replication, recombination and repair];


Pssm-ID: 442817 [Multi-domain]  Cd Length: 313  Bit Score: 63.38  E-value: 2.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 112 LLQGGIETGSITEMFGEFRTGKT----QIChtLAVTCQLP-IDRGGGEGKAMYIDTEGTFRP--ERLLAVAERYGLSGSD 184
Cdd:COG3598    5 LVPGLLPEGGVTLLAGPPGTGKSflalQLA--AAVAAGGPwLGRRVPPGKVLYLAAEDDRGElrRRLKALGADLGLPFAD 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 185 VLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDysgrgELSARQMhlARFLRMLLRLADEFGVAVV 264
Cdd:COG3598   83 LDGRLRLLSLAGDLDDTDDLEALERAIEEEGPDLVVIDPLARVFGGD-----ENDAEEM--RAFLNPLDRLAERTGAAVL 155
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 767984892 265 ItnqvVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETR 310
Cdd:COG3598  156 L----VHHTGKGGAGKDSGDRARGSSALRGAARSVLVLSREKGEDL 197
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
102-305 3.08e-10

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 59.49  E-value: 3.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLL-QGGIETGSITEMFGEFRTGKTqichTLAVTCQLPIDRGGgeGKAMYIDTEGTFRPErllaVAERYGL 180
Cdd:cd00983    5 IPTGSLSLDIALgIGGLPRGRIIEIYGPESSGKT----TLALHAIAEAQKLG--GTAAFIDAEHALDPE----YAKKLGV 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 181 SgsdvLDNVAYARAfntDHQTQLLYQASAMMVESRYALLIVDSATALY-RTDYSgrGELSARQMHL-AR----FLRMLLR 254
Cdd:cd00983   75 D----IDNLLVSQP---DTGEQALEIADTLIRSGAVDLIVVDSVAALVpKAEIE--GEMGDSHVGLqARlmsqALRKLTG 145
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767984892 255 LADEFGVAVVITNQVVAQVdgAAMFAAdPKKPIGGNIIAHASTTRLYLRKG 305
Cdd:cd00983  146 SLSKSKTTVIFINQLREKI--GVMFGN-PETTTGGNALKFYASVRLDIRRI 193
HHH_5 pfam14520
Helix-hairpin-helix domain;
32-80 3.17e-08

Helix-hairpin-helix domain;


Pssm-ID: 434010 [Multi-domain]  Cd Length: 57  Bit Score: 49.41  E-value: 3.17e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 767984892   32 GINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAK 80
Cdd:pfam14520   9 GIGPKTALALLSAGIGTVEDLAEADVDELAEIPGIGEKTAQRIILELRD 57
AAA_25 pfam13481
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
88-266 6.82e-08

AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.


Pssm-ID: 463892 [Multi-domain]  Cd Length: 193  Bit Score: 52.00  E-value: 6.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   88 TATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTC-----QLPIDRGGGEGKAMYIDT 162
Cdd:pfam13481   1 TAEPLELLDVLADGLAAPPPPRRWLIKGLLPAGGLGLLAGAPGTGKTTLALDLAAAVatgkpWLGGPRVPEQGKVLYVSA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  163 EGTFR--PERLLAVAERYGLSGS-DVLDNVAYARAFNTDHQTQLLYQASAMMVES-----RYALLIVDSATALYrtdysG 234
Cdd:pfam13481  81 EGPADelRRRLRAAGADLDLPARlLFLSLVESLPLFFLDRGGPLLDADVDALEAAleeveDPDLVVIDPLARAL-----G 155
                         170       180       190
                  ....*....|....*....|....*....|..
gi 767984892  235 RGELSARQMhlARFLRMLLRLADEFGVAVVIT 266
Cdd:pfam13481 156 GDENSNSDV--GRLVKALDRLARRTGATVLLV 185
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
94-304 4.03e-07

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 50.48  E-value: 4.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892   94 QRRSEIIQITTGSKELDKLLQ-GGIETGSITEMFGEFRTGKTQIchTLAVTCQlpIDRGGgeGKAMYIDTEGTFRPerll 172
Cdd:pfam00154  25 EKKLDVETISTGSLALDIALGiGGYPKGRIIEIYGPESSGKTTL--ALHAIAE--AQKAG--GTAAFIDAEHALDP---- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  173 AVAERYGLSgsdvLDNVAYARAfntDHQTQLLYQASAMMVESRYALLIVDSATALY-RTDYSGR-GE----LSARQMHLA 246
Cdd:pfam00154  95 VYAKKLGVD----IDNLLVSQP---DTGEQALEIADMLVRSGAIDLIVVDSVAALVpKAEIEGEmGDshvgLQARLMSQA 167
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767984892  247 rfLRMLLRLADEFGVAVVITNQVVAQVdgAAMFaADPKKPIGGNIIAHASTTRLYLRK 304
Cdd:pfam00154 168 --LRKLTGSISKSNTTVIFINQIREKI--GVMF-GNPETTTGGRALKFYASVRLDIRR 220
PRK06067 PRK06067
flagellar accessory protein FlaH; Validated
102-266 3.91e-06

flagellar accessory protein FlaH; Validated


Pssm-ID: 180381  Cd Length: 234  Bit Score: 47.27  E-value: 3.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTqichtlaVTCQLPIDRGGGEGKAM-YIDTEGTFRpeRLLAVAERYGL 180
Cdd:PRK06067   7 ISTGNEELDRKLGGGIPFPSLILIEGDHGTGKS-------VLSQQFVYGALKQGKKVyVITTENTSK--SYLKQMESVKI 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 181 sgsDVLDNVA--YARAF---------NTDHQTQLLYQASAMMVESRYALLIVDSATALyrTDYsgrgelsARQMHLARFL 249
Cdd:PRK06067  78 ---DISDFFLwgYLRIFplntegfewNSTLANKLLELIIEFIKSKREDVIIIDSLTIF--ATY-------AEEDDILNFL 145
                        170
                 ....*....|....*..
gi 767984892 250 RMLLRLADEfGVAVVIT 266
Cdd:PRK06067 146 TEAKNLVDL-GKTILIT 161
RadA_SMS_N cd01121
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ...
97-269 8.88e-05

bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.


Pssm-ID: 410866 [Multi-domain]  Cd Length: 268  Bit Score: 43.29  E-value: 8.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892  97 SEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKT----QICHTLAvtcqlpidrgGGEGKAMYIDTEGTfrPERLL 172
Cdd:cd01121   59 EEEERISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKStlllQVAARLA----------QRGGKVLYVSGEES--LSQIK 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 173 AVAERYGLSGSDV-------LDNVAyarafntdhqtqllyqasAMMVESRYALLIVDSATALYRTDYSG--------RgE 237
Cdd:cd01121  127 LRAERLGLGSDNLyllaetnLEAIL------------------AEIEELKPSLVVIDSIQTVYSPELTSspgsvsqvR-E 187
                        170       180       190
                 ....*....|....*....|....*....|..
gi 767984892 238 LSARqmhlarflrmLLRLADEFGVAVVITNQV 269
Cdd:cd01121  188 CAAE----------LLRLAKETGIPVFLVGHV 209
RepA_RSF1010_like cd01125
Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family ...
155-265 4.53e-04

Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family includes the homo-hexameric replicative helicase RepA encoded by plasmid RSF1010. RSF1010 is found in most Gram-negative bacteria and some Gram-positive bacteria . The RepA protein of Plasmid RSF1010 is a 5'-3' DNA helicase which can utilize ATP, dATP, GTP and dGTP (and CTP and dCTP to a lesser extent).


Pssm-ID: 410870  Cd Length: 238  Bit Score: 41.21  E-value: 4.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 155 GKAMYIDTEGTFR--PERLLAVAERYGLSGSDVLDN--VAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSataLYRT 230
Cdd:cd01125   40 GRVVYLAAEDPRDglRRRLKAIGAHLGDEDAALAENlvIENLRGKPVSIDAEAPELERIIEELEGVRLIIIDT---LARV 116
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 767984892 231 DYSGRgELSARQMhlARFLRMLLRLADEFGVAVVI 265
Cdd:cd01125  117 LHGGD-ENDAADM--GAFVAGLDRIARETGAAVLL 148
PRK09302 PRK09302
circadian clock protein KaiC; Reviewed
88-163 4.78e-04

circadian clock protein KaiC; Reviewed


Pssm-ID: 236461 [Multi-domain]  Cd Length: 509  Bit Score: 41.79  E-value: 4.78e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767984892  88 TATEFHQRRSEIIqITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQI-CHTLAVTCQlpidrgGGEgKAMYIDTE 163
Cdd:PRK09302 242 TAMRLTQRSSNER-ISSGVPDLDEMLGGGFFRGSIILVSGATGTGKTLLaSKFAEAACR------RGE-RCLLFAFE 310
KaiC-like cd01124
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ...
102-310 5.03e-04

Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.


Pssm-ID: 410869 [Multi-domain]  Cd Length: 222  Bit Score: 40.71  E-value: 5.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTcQLPIDrgggeGKAMYIDTEGTfrPERLLAVAERYG-- 179
Cdd:cd01124    1 VKTGIPGLDELLGGGIPKGSVTLLTGGPGTGKTLFGLQFLYA-GAKNG-----EPGLFFTFEES--PERLLRNAKSFGwd 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767984892 180 LSGSDVLDNVAYARAFNTDHQTQLLYQASAMM---VES-RYALLIVDSATALYRtdysgrgeLSARQMHLARFLRMLLRL 255
Cdd:cd01124   73 FDEMEDEGKLIIVDAPPTEAGRFSLDELLSRIlsiIKSfKAKRVVIDSLSGLRR--------AKEDQMRARRIVIALLNE 144
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767984892 256 ADEFGVAVVITNQV------VAQVDGAAMFAADpkkpiggNIIahasttRLYLRKGRGETR 310
Cdd:cd01124  145 LRAAGVTTIFTSEMrsflssESAGGGDVSFIVD-------GVI------LLRYVEIEGELR 192
MUS81 COG1948
ERCC4-type crossover junction endonuclease [Replication, recombination and repair];
41-74 6.36e-04

ERCC4-type crossover junction endonuclease [Replication, recombination and repair];


Pssm-ID: 441551 [Multi-domain]  Cd Length: 214  Bit Score: 40.54  E-value: 6.36e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 767984892  41 LEEagFHTVEAVAYAPKKELINIKGISEAKADKI 74
Cdd:COG1948  172 LEH--FGSVEAVFNASEEELMKVEGIGEKTAERI 203
nusA_Cterm_rpt TIGR01954
transcription termination factor NusA, C-terminal duplication; NusA is a bacterial ...
33-78 8.20e-04

transcription termination factor NusA, C-terminal duplication; NusA is a bacterial transcription termination factor. It is named for its interaction with phage lambda protein N, as part of the N utilization substance. Some members of the NusA family have a long C-terminal extension. This model represents an acidic 50-residue region found in two copies toward the C-terminus of most Proteobacterial NusA proteins, spaced about 26 residues apart. Analogous C-terminal extensions in some other bacterial lineages lack apparent homology but appear similarly acidic. [Transcription, Transcription factors]


Pssm-ID: 273894 [Multi-domain]  Cd Length: 50  Bit Score: 36.90  E-value: 8.20e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 767984892   33 INANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEA 78
Cdd:TIGR01954   1 INEEIAQLLVEEGFTTVEDLAYVPIDELLSIEGFDEETAKELINRA 46
FlaH COG2874
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];
102-137 1.22e-03

Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];


Pssm-ID: 442121  Cd Length: 230  Bit Score: 39.82  E-value: 1.22e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 767984892 102 ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQIC 137
Cdd:COG2874    3 ISTGNDELDKRLGGGIPLGSLVLIEGENGTGKSVLS 38
PRK08533 PRK08533
flagellar accessory protein FlaH; Reviewed
98-141 6.16e-03

flagellar accessory protein FlaH; Reviewed


Pssm-ID: 181459  Cd Length: 230  Bit Score: 37.74  E-value: 6.16e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 767984892  98 EIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLA 141
Cdd:PRK08533   2 ELAKIELSRDELHKRLGGGIPAGSLILIEGDESTGKSILSQRLA 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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