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Conserved domains on  [gi|767993474|ref|XP_011522590|]
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putative sodium-coupled neutral amino acid transporter 10 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SLC5-6-like_sbd super family cl00456
Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the ...
 6-388 1.33e-52

Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporters or solute sodium symporters), SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporters or Na+/Cl--dependent transporters), and nucleobase-cation-symport-1 (NCS1) transporters. SLC5s co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. SLC6s include Na+/Cl--dependent plasma membrane transporters for the monoamine neurotransmitters serotonin, dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. Members of this superfamily are important in human physiology and disease. They contain a functional core of 10 transmembrane helices (TMs): an inverted structural repeat, TMs1-5 and TMs6-10; TMs numbered to conform to the SLC6 Aquifex aeolicus LeuT.


The actual alignment was detected with superfamily member pfam01490:

Pssm-ID: 444915  Cd Length: 410  Bit Score: 190.59  E-value: 1.33e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474     6 ASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLGeapspqa 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLG------- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474    81 FHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS 159
Cdd:pfam01490   76 YRLLGPKGRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILS 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   160 -FSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIF 237
Cdd:pfam01490  153 lLAAVSSLYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKIL 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   238 ASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGT 316
Cdd:pfam01490  233 LTAIIIATVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAP 309

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767993474   317 FAAGGYMPP---LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 388
Cdd:pfam01490  310 FGASGKNNPkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 538-991 1.69e-08

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 58.84  E-value: 1.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  538 APGVQGQMAPPLPDSER-EKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 616
Cdd:PRK07764  364 LPSASDDERGLLARLERlERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPS 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  617 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAedsdhggkpPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLE- 695
Cdd:PRK07764  444 PAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPT---------AAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRe 514

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  696 --AEIKKIVAEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkpr 761
Cdd:PRK07764  515 rwPEILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE------ 585

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  762 qVEVHQEPGAAVPRGQEAPEGKARETvenlpPLPLDPVLRAPGGRPAPSQDlnQRSLEHSEGPVGRDPAGPPdgGPDTEP 841
Cdd:PRK07764  586 -AVVGPAPGAAGGEGPPAPASSGPPE-----EAARPAAPAAPAAPAAPAPA--GAAAAPAEASAAPAPGVAA--PEHHPK 655

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  842 RAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERlaeefPGQSQDVTGGSQDRKKPGKEVAATGTSI 921
Cdd:PRK07764  656 HVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA-----PAPAATPPAGQADDPAAQPPQAAQGASA 730

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  922 LKEANWlVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHR 991
Cdd:PRK07764  731 PSPAAD-DPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 6-388 1.33e-52

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 190.59  E-value: 1.33e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474     6 ASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLGeapspqa 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLG------- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474    81 FHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS 159
Cdd:pfam01490   76 YRLLGPKGRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILS 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   160 -FSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIF 237
Cdd:pfam01490  153 lLAAVSSLYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKIL 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   238 ASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGT 316
Cdd:pfam01490  233 LTAIIIATVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAP 309

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767993474   317 FAAGGYMPP---LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 388
Cdd:pfam01490  310 FGASGKNNPkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
 14-373 8.23e-24

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 106.49  E-value: 8.23e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   14 NIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLGEApspqafhAYGKAGKMLVE 93
Cdd:PTZ00206   68 NIASSTVGAGIVGLPSAANSSGLVMAMIYLIIITAMTIFSIYALGVAADKTNIRTYEGVARV-------LLGPWGSYYVA 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   94 TSMIGLMLGTCIAFYVVIGDL------GSNffARLFGFQVGGTfrMFLLFAVSLCIVLPLSLQRNMmASIQSFSAMALLF 167
Cdd:PTZ00206  141 ATRAFHGFSACVAYVISVGDIlsatlkGTN--APDFLKQKSGN--RLLTSLMWLCFMLPLVIPRHI-DSLRYVSTIAVSF 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  168 YTVFMFVIVLSSLKHGLfsGQWLRRVSY--------VRWEGVFRCIP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSI 236
Cdd:PTZ00206  216 MVYLVIVIVVHSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLA 293

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  237 FASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHF-PSNLVTEMLR-VGFMMSVAVGFPMMILPCRQALSTLLCEQQQKD 314
Cdd:PTZ00206  294 STIAMGMCFTMYVLTAFFGYMDFGRNVTGSVLLMYdPVNEPAIMVGfVGVLVKLFVSYALLGMACRNALYDVIGWDARKV 373

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767993474  315 GTFAAGgympplrFKALTLSVVFgtMVGGILIPNVETILGLTGATMGSLICFICPALIY 373
Cdd:PTZ00206  374 AFWKHC-------IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 538-991 1.69e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 58.84  E-value: 1.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  538 APGVQGQMAPPLPDSER-EKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 616
Cdd:PRK07764  364 LPSASDDERGLLARLERlERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPS 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  617 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAedsdhggkpPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLE- 695
Cdd:PRK07764  444 PAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPT---------AAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRe 514

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  696 --AEIKKIVAEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkpr 761
Cdd:PRK07764  515 rwPEILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE------ 585

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  762 qVEVHQEPGAAVPRGQEAPEGKARETvenlpPLPLDPVLRAPGGRPAPSQDlnQRSLEHSEGPVGRDPAGPPdgGPDTEP 841
Cdd:PRK07764  586 -AVVGPAPGAAGGEGPPAPASSGPPE-----EAARPAAPAAPAAPAAPAPA--GAAAAPAEASAAPAPGVAA--PEHHPK 655

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  842 RAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERlaeefPGQSQDVTGGSQDRKKPGKEVAATGTSI 921
Cdd:PRK07764  656 HVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA-----PAPAATPPAGQADDPAAQPPQAAQGASA 730

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  922 LKEANWlVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHR 991
Cdd:PRK07764  731 PSPAAD-DPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 406-731 8.73e-04

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 43.51  E-value: 8.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  406 EEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQD---------PVVAVAEDGREKPKL-PKEREELEQAQIKGPVDVPGR 475
Cdd:COG5180   160 PILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKdspekldrpKVEVKDEAQEEPPDLtGGADHPRPEAASSPKVDPPST 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  476 EDGKEAPeeaqLDRPGQGIAVPVGEAHRHEPPVPHDKvvvDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSERE 555
Cdd:COG5180   240 SEARSRP----ATVDAQPEMRPPADAKERRRAAIGDT---PAAEPPGLPVLEAGSEPQSDAPEAETARPIDVKGVASAPP 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  556 KQEPEQGEVGKRPGQAQALEEAGdlpEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKG 635
Cdd:COG5180   313 ATRPVRPPGGARDPGTPRPGQPT---ERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  636 GPPPGN---AAGDTGQPAED-----SDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEAEIKKIVAEAGR 707
Cdd:COG5180   390 APQPGLgrrGAPGPPMGAGDlvqaaLDGGGRETASLGGAAGGAGQGPKADFVPGDAESVSGPAGLADQAGAAASTAMADF 469

                         330       340
                  ....*....|....*....|....
gi 767993474  708 AEMLDHAVLLQVIKEQQVQQKRLL 731
Cdd:COG5180   470 VAPVTDATPVDVADVLGVRPDAIL 493
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 539-687 9.42e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 39.75  E-value: 9.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  539 PGVQGQMAPPLPDSEREKQEPEQG--EVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 616
Cdd:NF040712  170 PGAHGGTVTALDDEARWLIDPDFGrpLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRR 249

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767993474  617 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPG-PGLPPEPREQRDVERAGG 687
Cdd:NF040712  250 AGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPaAPAAPEAEEPARPEPPPA 321
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 6-388 1.33e-52

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 190.59  E-value: 1.33e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474     6 ASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLGeapspqa 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLG------- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474    81 FHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS 159
Cdd:pfam01490   76 YRLLGPKGRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILS 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   160 -FSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIF 237
Cdd:pfam01490  153 lLAAVSSLYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKIL 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   238 ASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGT 316
Cdd:pfam01490  233 LTAIIIATVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAP 309

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767993474   317 FAAGGYMPP---LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 388
Cdd:pfam01490  310 FGASGKNNPkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
 14-373 8.23e-24

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 106.49  E-value: 8.23e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   14 NIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLGEApspqafhAYGKAGKMLVE 93
Cdd:PTZ00206   68 NIASSTVGAGIVGLPSAANSSGLVMAMIYLIIITAMTIFSIYALGVAADKTNIRTYEGVARV-------LLGPWGSYYVA 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474   94 TSMIGLMLGTCIAFYVVIGDL------GSNffARLFGFQVGGTfrMFLLFAVSLCIVLPLSLQRNMmASIQSFSAMALLF 167
Cdd:PTZ00206  141 ATRAFHGFSACVAYVISVGDIlsatlkGTN--APDFLKQKSGN--RLLTSLMWLCFMLPLVIPRHI-DSLRYVSTIAVSF 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  168 YTVFMFVIVLSSLKHGLfsGQWLRRVSY--------VRWEGVFRCIP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSI 236
Cdd:PTZ00206  216 MVYLVIVIVVHSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLA 293

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  237 FASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHF-PSNLVTEMLR-VGFMMSVAVGFPMMILPCRQALSTLLCEQQQKD 314
Cdd:PTZ00206  294 STIAMGMCFTMYVLTAFFGYMDFGRNVTGSVLLMYdPVNEPAIMVGfVGVLVKLFVSYALLGMACRNALYDVIGWDARKV 373

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767993474  315 GTFAAGgympplrFKALTLSVVFgtMVGGILIPNVETILGLTGATMGSLICFICPALIY 373
Cdd:PTZ00206  374 AFWKHC-------IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 538-991 1.69e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 58.84  E-value: 1.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  538 APGVQGQMAPPLPDSER-EKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 616
Cdd:PRK07764  364 LPSASDDERGLLARLERlERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPS 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  617 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAedsdhggkpPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLE- 695
Cdd:PRK07764  444 PAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPT---------AAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRe 514

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  696 --AEIKKIVAEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkpr 761
Cdd:PRK07764  515 rwPEILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE------ 585

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  762 qVEVHQEPGAAVPRGQEAPEGKARETvenlpPLPLDPVLRAPGGRPAPSQDlnQRSLEHSEGPVGRDPAGPPdgGPDTEP 841
Cdd:PRK07764  586 -AVVGPAPGAAGGEGPPAPASSGPPE-----EAARPAAPAAPAAPAAPAPA--GAAAAPAEASAAPAPGVAA--PEHHPK 655

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  842 RAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERlaeefPGQSQDVTGGSQDRKKPGKEVAATGTSI 921
Cdd:PRK07764  656 HVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA-----PAPAATPPAGQADDPAAQPPQAAQGASA 730

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  922 LKEANWlVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHR 991
Cdd:PRK07764  731 PSPAAD-DPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 524-692 1.42e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 1.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  524 PEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPA-VQPAKED 602
Cdd:PRK07764  606 SGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAApAAPPPAP 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  603 LGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDV 682
Cdd:PRK07764  686 APAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPA 765

                         170
                  ....*....|
gi 767993474  683 ERAGGNQAAS 692
Cdd:PRK07764  766 PAAAPAAAPP 775
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
771-981 1.76e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 45.61  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  771 AAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPsQDLNQRSLEHSEGPVGRdPAGPPDGGPDTEPRAAQAKLrd 850
Cdd:PRK07003  374 ARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAP-KAAAAAAATRAEAPPAA-PAPPATADRGDDAADGDAPV-- 449

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  851 gQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDvtggsqdrkkpgkEVAATGTSILKEANWLVA 930
Cdd:PRK07003  450 -PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAA-------------APSAATPAAVPDARAPAA 515

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767993474  931 GPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISD 981
Cdd:PRK07003  516 ASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSD 566
PHA03169 PHA03169
hypothetical protein; Provisional
 455-677 1.88e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 45.35  E-value: 1.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  455 PKEREELEQAQIKGPVDVPGREDGKEAPEEaqldRPGQGIAVPVGE--AHRHEPPVPHDKVVVDEGQDREVPEENKP--P 530
Cdd:PHA03169   56 PQVRAVAEQGHRQTESDTETAEESRHGEKE----ERGQGGPSGSGSesVGSPTPSPSGSAEELASGLSPENTSGSSPesP 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  531 SRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQaqalEEAGDLPEDPQKVPEADGQPAVQ-PAKEDLGP-GDR 608
Cdd:PHA03169  132 ASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSH----EDSPEEPEPPTSEPEPDSPGPPQsETPTSSPPpQSP 207

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767993474  609 GLHPRPQavlseqqnglavgGGEKAKGGPPPgnaagDTGQPAEDSDHggkpplPAEKPAPGPGlPPEPR 677
Cdd:PHA03169  208 PDEPGEP-------------QSPTPQQAPSP-----NTQQAVEHEDE------PTEPEREGPP-FPGHR 251
PHA03247 PHA03247
large tegument protein UL36; Provisional
 455-945 2.01e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 2.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  455 PKEREELEQAQIKGPvDVPGREDGKEAPEEAQLDRPGQGIAVPVgeahrhePPVPHdkvvvdegqdrevPEENKPPSRHA 534
Cdd:PHA03247 2575 PRPSEPAVTSRARRP-DAPPQSARPRAPVDDRGDPRGPAPPSPL-------PPDTH-------------APDPPPPSPSP 2633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  535 GGKAPGVQGQMAPPLPdsEREKQEPEQGEVgKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQP--AKEDLGPGDRGLHP 612
Cdd:PHA03247 2634 AANEPDPHPPPTVPPP--ERPRDDPAPGRV-SRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltSLADPPPPPPTPEP 2710

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  613 RPQAVLSEQQNGLAVGGGEKAKGGPP----PGNAAGDTGQPAEDSdHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGN 688
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPALPaapaPPAVPAGPATPGGPA-RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  689 QAASQLEAEIKKIVAEAGRAEMLDHAVllqvikeqqvqqkrlldqqekllavieeqhkeihqqrqedeedkprqvevhQE 768
Cdd:PHA03247 2790 SLSESRESLPSPWDPADPPAAVLAPAA---------------------------------------------------AL 2818

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  769 PGAAVPRGQEAPEGKARETVENLPPLPLDPVLrAPGGRPAPSQDLNQRSlehsegpvgrdPAGPPDGGPDTEPRAAQAKL 848
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRP-----------PSRSPAAKPAAPARPPVRRL 2886

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  849 rdgQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATG-TSILKEANW 927
Cdd:PHA03247 2887 ---ARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGePSGAVPQPW 2963

                         490
                  ....*....|....*...
gi 767993474  928 LVAGPGAETGDPRMKPKQ 945
Cdd:PHA03247 2964 LGALVPGRVAVPRFRVPQ 2981
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 439-889 2.05e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.85  E-value: 2.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  439 DPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGE---AHRHEPPVPHDKVVV 515
Cdd:PRK10263  370 EPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQpyyAPAPEQPVAGNAWQA 449

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  516 DEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPlPDSEREKQEPEQGEVGKRPGQAQA--LEEAGDLPEDPQKVPEADGQ 593
Cdd:PRK10263  450 EEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQ-PVEQQPVVEPEPVVEETKPARPPLyyFEEVEEKRAREREQLAAWYQ 528

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  594 PAVQPAKEDLgPGDRGLHPRPQAVLSEQQNGLAVGG-GEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPlPAEKPAPGPGL 672
Cdd:PRK10263  529 PIPEPVKEPE-PIKSSLKAPSVAAVPPVEAAAAVSPlASGVKKATLATGAAATVAAPVFSLANSGGPR-PQVKEGIGPQL 606

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  673 PPEPREQRDVER---AGGNQAASQLEAEIKKIVAEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIH 749
Cdd:PRK10263  607 PRPKRIRVPTRRelaSYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPV 686

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  750 QQRQED---EEDKPRQVEVHQE-------PGAAVPRGQEAPE-GKARETVENLPPLPLDPVLRAPGGRPApSQDLNQRSL 818
Cdd:PRK10263  687 NAEDADaaaEAELARQFAQTQQqrysgeqPAGANPFSLDDFEfSPMKALLDDGPHEPLFTPIVEPVQQPQ-QPVAPQQQY 765

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  819 EHSEGPVG--------RDPAGPP-DGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPE---QVPVPDPAREaggPE 886
Cdd:PRK10263  766 QQPQQPVApqpqyqqpQQPVAPQpQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQ---PQ 842


                  ...
gi 767993474  887 ERL 889
Cdd:PRK10263  843 DTL 845
PHA03169 PHA03169
hypothetical protein; Provisional
 509-683 6.14e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.42  E-value: 6.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  509 PHDKVVVDEGQDR-EVPEENKPPSRHAGGKAPGVQGqmapPLPDSEREKQEPEQGEVGKRPGQAQALE--------EAGD 579
Cdd:PHA03169   56 PQVRAVAEQGHRQtESDTETAEESRHGEKEERGQGG----PSGSGSESVGSPTPSPSGSAEELASGLSpentsgssPESP 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  580 LPEDPQKVPEADGQPAVQPAKEDLGP-----GDRGLHPRPQAVLSEqqnglavggGEKAKGGPPPGNAAGDTGQPAEDSD 654
Cdd:PHA03169  132 ASHSPPPSPPSHPGPHEPAPPESHNPspnqqPSSFLQPSHEDSPEE---------PEPPTSEPEPDSPGPPQSETPTSSP 202

                         170       180       190
                  ....*....|....*....|....*....|
gi 767993474  655 HGGKPP-LPAEKPAPGPGLPPEPREQRDVE 683
Cdd:PHA03169  203 PPQSPPdEPGEPQSPTPQQAPSPNTQQAVE 232
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 406-731 8.73e-04

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 43.51  E-value: 8.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  406 EEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQD---------PVVAVAEDGREKPKL-PKEREELEQAQIKGPVDVPGR 475
Cdd:COG5180   160 PILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKdspekldrpKVEVKDEAQEEPPDLtGGADHPRPEAASSPKVDPPST 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  476 EDGKEAPeeaqLDRPGQGIAVPVGEAHRHEPPVPHDKvvvDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSERE 555
Cdd:COG5180   240 SEARSRP----ATVDAQPEMRPPADAKERRRAAIGDT---PAAEPPGLPVLEAGSEPQSDAPEAETARPIDVKGVASAPP 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  556 KQEPEQGEVGKRPGQAQALEEAGdlpEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKG 635
Cdd:COG5180   313 ATRPVRPPGGARDPGTPRPGQPT---ERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  636 GPPPGN---AAGDTGQPAED-----SDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEAEIKKIVAEAGR 707
Cdd:COG5180   390 APQPGLgrrGAPGPPMGAGDlvqaaLDGGGRETASLGGAAGGAGQGPKADFVPGDAESVSGPAGLADQAGAAASTAMADF 469

                         330       340
                  ....*....|....*....|....
gi 767993474  708 AEMLDHAVLLQVIKEQQVQQKRLL 731
Cdd:COG5180   470 VAPVTDATPVDVADVLGVRPDAIL 493
PHA03321 PHA03321
tegument protein VP11/12; Provisional
 475-676 1.01e-03

tegument protein VP11/12; Provisional


Pssm-ID: 223041 [Multi-domain]  Cd Length: 694  Bit Score: 43.41  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  475 REDgkEAPEEAQLDRPGQGIAVPVgEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQM---APPLPD 551
Cdd:PHA03321  437 RRD--NDPPPPPRARPGSTPACAR-RARAQRARDAGPEYVDPLGALRRLPAGAAPPPEPAAAPSPATYYTRmggGPPRLP 513

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  552 SeREKQEPEQgevgkRPGQAQALEEAGDLPEDPQKVPEADGQPAvqpakEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGE 631
Cdd:PHA03321  514 P-RNRATETL-----RPDWGPPAAAPPEQMEDPYLEPDDDRFDR-----RDGAAAAATSHPREAPAPDDDPIYEGVSDSE 582

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767993474  632 ---------------------KAKGGPPPGNAAGDTGQPAEDSDHG------GKPPLPAEKPAPGPGLPPEP 676
Cdd:PHA03321  583 epvyeeiptprvyqnplprpmEGAGEPPDLDAPTSPWVEEENPIYGwgdsplFSPPPAARFPPPDPALSPEP 654
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 403-681 1.43e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.85  E-value: 1.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  403 SVSEEVPEDLAEEAPG---GRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGK 479
Cdd:PHA03307   26 ATPGDAADDLLSGSQGqlvSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGS 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  480 EAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQ-GQMAPPLPDSEREKQE 558
Cdd:PHA03307  106 PTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASsRQAALPLSSPEETARA 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  559 PEQGEVGKRPGQAQALEEAGDLPEDPqkvPEADGQPAVQPAkeDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPP 638
Cdd:PHA03307  186 PSSPPAEPPPSTPPAAASPRPPRRSS---PISASASSPAPA--PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRP 260

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 767993474  639 PGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRD 681
Cdd:PHA03307  261 APITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
677-765 2.95e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 41.40  E-value: 2.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  677 REQRDVERAggnQAASQLEAEIKKIVAEAgraemldhAVLLQ-VIKEQQVQQKRLLDQQEKllaVIEEQHKEIHQQRQED 755
Cdd:COG2268   241 EAEAELAKK---KAEERREAETARAEAEA--------AYEIAeANAEREVQRQLEIAERER---EIELQEKEAEREEAEL 306

                          90
                  ....*....|
gi 767993474  756 EEDKPRQVEV 765
Cdd:COG2268   307 EADVRKPAEA 316
dnaA PRK14086
chromosomal replication initiator protein DnaA;
546-689 4.26e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 40.96  E-value: 4.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  546 APPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPqkvPEADGQPAVQPAKEDLGPGDR-GLHPRPQAVLSEQQNG 624
Cdd:PRK14086   95 PAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGL---PRQDQLPTARPAYPAYQQRPEpGAWPRAADDYGWQQQR 171

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767993474  625 LavgggekakgGPPPGNaagDTGQPAEDSdhggkPPLPAEKPAPGPGLPPEPREQRDVERAGGNQ 689
Cdd:PRK14086  172 L----------GFPPRA---PYASPASYA-----PEQERDREPYDAGRPEYDQRRRDYDHPRPDW 218
PHA03247 PHA03247
large tegument protein UL36; Provisional
 440-670 4.51e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 4.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  440 PVVAVAEDGREKPKLPKEREELEQaqikgPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKV---VVD 516
Cdd:PHA03247 2784 TRPAVASLSESRESLPSPWDPADP-----PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggsVAP 2858

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  517 EGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEvgKRPGQAQAleeagdlPEDPQKVPEADGQPAV 596
Cdd:PHA03247 2859 GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQP--ERPPQPQA-------PPPPQPQPQPPPPPQP 2929

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767993474  597 QPAKEDlgpgdrglHPRPQAVLSEQQNglAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGP 670
Cdd:PHA03247 2930 QPPPPP--------PPRPQPPLAPTTD--PAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASST 2993
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
528-691 4.99e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.99  E-value: 4.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  528 KPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGD 607
Cdd:PRK07003  386 RAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDE 465

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  608 RGLHPRPQAVLSEQQNGLAVGGGEKAKgGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLP----PEPREQRDVE 683
Cdd:PRK07003  466 RDAQPPADSGSASAPASDAPPDAAFEP-APRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPearpPTPAAAAPAA 544


                  ....*...
gi 767993474  684 RAGGNQAA 691
Cdd:PRK07003  545 RAGGAAAA 552
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 494-683 5.21e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 5.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  494 IAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPG----VQGQMAPPLPDSEREKQEPEQGEVGKRP- 568
Cdd:PRK07764  588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAapaeASAAPAPGVAAPEHHPKHVAVPDASDGGd 667

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  569 GQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEK---AKGGPPPGNAAGD 645
Cdd:PRK07764  668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPspaADDPVPLPPEPDD 747

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 767993474  646 TGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVE 683
Cdd:PRK07764  748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEM 785
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 756-893 5.62e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 5.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  756 EEDKPRQVEVHQEPGAAVPRGQEAPEGKAREtvenlpplpldpvlrAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDG 835
Cdd:PRK07764  679 AAPPPAPAPAAPAAPAGAAPAQPAPAPAATP---------------PAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP 743

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767993474  836 GPDTEPRAAQAKLRDGQKDAAPRAAGTVKELP---KGPEQVPVPDPAREAGGPEERLAEEF 893
Cdd:PRK07764  744 EPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPpspPSEEEEMAEDDAPSMDDEDRRDAEEV 804
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 419-698 6.67e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 6.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  419 GRLGEAEGLMKVEAARLSAQDPVVAVAEDGReKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPV 498
Cdd:PRK07764  562 ASPGNAEVLVTALAEELGGDWQVEAVVGPAP-GAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEAS 640

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  499 GEAHRHEPPVPHDKVVVDEGqdrevPEENKPPSRHAGGKAPGVQGQMAPPLPDSerekQEPEQGEVGKRPGQAQALEEAG 578
Cdd:PRK07764  641 AAPAPGVAAPEHHPKHVAVP-----DASDGGDGWPAKAGGAAPAAPPPAPAPAA----PAAPAGAAPAQPAPAPAATPPA 711

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  579 DLPEDPQKVPEADGQPAVQPAkeDLGPGDRGLHPRPqavlSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAedsdhggk 658
Cdd:PRK07764  712 GQADDPAAQPPQAAQGASAPS--PAADDPVPLPPEP----DDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPS-------- 777

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 767993474  659 PPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEAEI 698
Cdd:PRK07764  778 PPSEEEEMAEDDAPSMDDEDRRDAEEVAMELLEEELGAKK 817
rne PRK10811
ribonuclease E; Reviewed
 544-763 7.05e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 40.79  E-value: 7.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  544 QMAPPLPDSEREKQEPEQgevgkrPGQAqaleeAGDLPEDPQKVPEAdgQPAVQPAKEDlgpgdrglhPRPQAVLSEQQN 623
Cdd:PRK10811  509 AMALPSEEEFAERKRPEQ------PALA-----TFAMPDVPPAPTPA--EPAAPVVAAA---------PKAAAATPPAQP 566

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  624 GL----------AVGGGEKAKGGPPPGNAAGDTGQPAEDS---------DHGGKPPLPAEKPAPgpglppEPREQRDVER 684
Cdd:PRK10811  567 GLlsrffgalkaLFSGGEETKPQEQPAPKAEAKPERQQDRrkprqnnrrDRNERRDTRDNRTRR------EGRENREENR 640

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  685 AGGNQAASQLEAEIKKIVAEAGRAEmldhavllqviKEQQVQQ--------------KRLLDQQEKLLAVIEEQHKEihq 750
Cdd:PRK10811  641 RNRRQAQQQTAETRESQQAEVTEKA-----------RTQDEQQqaprrerqrrrndeKRQAQQEAKALNVEEQSVQE--- 706

                         250
                  ....*....|...
gi 767993474  751 qrqEDEEDKPRQV 763
Cdd:PRK10811  707 ---TEQEERVQQV 716
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 688-789 8.75e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 39.79  E-value: 8.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  688 NQAASQLEAEIKKIVAEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAviEEQHKEIHQQRQEDEEDKPRQVEV-- 765
Cdd:PRK09510   69 QQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQA--EEAAKQAALKQKQAEEAAAKAAAAak 146

                          90       100
                  ....*....|....*....|....*...
gi 767993474  766 ----HQEPGAAVPRGQEAPEGKARETVE 789
Cdd:PRK09510  147 akaeAEAKRAAAAAKKAAAEAKKKAEAE 174
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 539-687 9.42e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 39.75  E-value: 9.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993474  539 PGVQGQMAPPLPDSEREKQEPEQG--EVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 616
Cdd:NF040712  170 PGAHGGTVTALDDEARWLIDPDFGrpLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRR 249

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767993474  617 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPG-PGLPPEPREQRDVERAGG 687
Cdd:NF040712  250 AGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPaAPAAPEAEEPARPEPPPA 321
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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