|
Name |
Accession |
Description |
Interval |
E-value |
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
575-1057 |
1.78e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.07 E-value: 1.78e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 575 RLKLEVEEKKQAMLLLQRALA---QQRDLTARRVKETEKALsRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAV 651
Cdd:COG1196 278 ELELELEEAQAEEYELLAELArleQDIARLEERRRELEERL-EELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 652 VAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEvtvrglepEIQKLIARHKQEVRRLKS 731
Cdd:COG1196 357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE--------ALLERLERLEEELEELEE 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 732 LHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQA 811
Cdd:COG1196 429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 812 ARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQ----MELNTLKQQLELERQAwEAGRTRKERMSPQEAWLL 887
Cdd:COG1196 509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQnivvEDDEVAAAAIEYLKAA-KAGRATFLPLDKIRARAA 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 888 NREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAE 967
Cdd:COG1196 588 LAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 968 GENLRLQGLVRQKERALEDAQAVNEQLSSE----RSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEGED 1043
Cdd:COG1196 668 RELLAALLEAEAELEELAERLAEEELELEEallaEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747
|
490
....*....|....
gi 767994123 1044 SPREEGGGREQPPD 1057
Cdd:COG1196 748 LEEEALEELPEPPD 761
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
765-1054 |
5.95e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.06 E-value: 5.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 765 ALGQQERERARQRFQQHLE--QEQWALQQQRQRlysEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEK 842
Cdd:COG1196 217 ELKEELKELEAELLLLKLRelEAELEELEAELE---ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 843 GRE----EQERRHQME----LNTLKQQLELERQAWEAGR----TRKERMSPQEAWLLNREQELREEIRKGRDKEIELVIH 910
Cdd:COG1196 294 LAElarlEQDIARLEErrreLEERLEELEEELAELEEELeeleEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 911 RLEAdmaLAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAV 990
Cdd:COG1196 374 LAEA---EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767994123 991 NEQLSSERSNLAQVIRQEfEDRLAASEEETRQAKAELATLQARQQLELEEGEDSPREEGGGREQ 1054
Cdd:COG1196 451 EAELEEEEEALLELLAEL-LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
577-1054 |
1.36e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 75.95 E-value: 1.36e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 577 KLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELK 656
Cdd:PTZ00121 1244 KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKK 1323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 657 QEDQRCTERVAQAQAQhelEIKKLKELMSATEKARREKwiSEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAE 736
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAE---EAKKAAEAAKAEAEAAADE--AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK 1398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 737 LLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEV---AEERERLGQ--QA 811
Cdd:PTZ00121 1399 KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAkkkAEEAKKADEakKK 1478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 812 ARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMelntlKQQLELERQAWEAGRTRKERMSPQEawllNREQ 891
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE-----AKKADEAKKAEEAKKADEAKKAEEK----KKAD 1549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 892 ELR--EEIRKGRDKEIELVIHRLEAD--MALAK-EESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKgQLGEA 966
Cdd:PTZ00121 1550 ELKkaEELKKAEEKKKAEEAKKAEEDknMALRKaEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE-ELKKA 1628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 967 EGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASE----EETRQAKAELATLQARQQLELEEGE 1042
Cdd:PTZ00121 1629 EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEakkaEEDEKKAAEALKKEAEEAKKAEELK 1708
|
490
....*....|..
gi 767994123 1043 DSPREEGGGREQ 1054
Cdd:PTZ00121 1709 KKEAEEKKKAEE 1720
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
718-1043 |
1.74e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 1.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 718 LIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALgQQERERARQRFQQHLEQEQwALQQQRQRL- 796
Cdd:COG1196 231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL-ELELEEAQAEEYELLAELA-RLEQDIARLe 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 797 --YSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKgrEEQERRHQMELNTLKQQLELERQAWEAGRT 874
Cdd:COG1196 309 erRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA--EAELAEAEEALLEAEAELAEAEEELEELAE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 875 RKERMSPQEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQE 954
Cdd:COG1196 387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 955 RCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSS---ERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQ 1031
Cdd:COG1196 467 ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvkAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAA 546
|
330
....*....|..
gi 767994123 1032 ARQQLELEEGED 1043
Cdd:COG1196 547 ALQNIVVEDDEV 558
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
606-1048 |
9.02e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.58 E-value: 9.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 606 KETEKALS-RQLQRQREHYEATIQrhLAFIDQLIEDKKVLsekcEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELM 684
Cdd:COG1196 207 RQAEKAERyRELKEELKELEAELL--LLKLRELEAELEEL----EAELEELEAELEELEAELAELEAELEELRLELEELE 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 685 SATEKARREkwISEKTKKIKEvtvrgLEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRclRQAEELREQLEREKE 764
Cdd:COG1196 281 LELEEAQAE--EYELLAELAR-----LEQDIARLEERRRELEERLEELEEELAELEEELEELE--EELEELEEELEEAEE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 765 AlgqqererarqrfqqhLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGR 844
Cdd:COG1196 352 E----------------LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 845 EEQERRHQMELNTLKQQLELERQAWEAGRTRkermspQEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESE 924
Cdd:COG1196 416 LERLEEELEELEEALAELEEEEEEEEEALEE------AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 925 KAAESRIKRLRDKYEAELSE-LEQSERKLQERCSELKGQLG------EAEGENLRLQGLVRQKERALEDAQAVNEQLSSE 997
Cdd:COG1196 490 AARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIgveaayEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 767994123 998 RSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEGEDSPREE 1048
Cdd:COG1196 570 KAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
567-1031 |
1.90e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 68.63 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 567 SEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHyeatiqrhlafIDQLIEDKKVLSE 646
Cdd:PTZ00121 1374 EEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----------KKKADEAKKKAEE 1442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 647 KCEAVVAELKQEDQRCTERvAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEV 726
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEE-AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEA 1521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 727 RRLKSLHEAE-------LLQSDERASQRCLRQAEELREQLEREK--EALGQQERERARQRFQQHLEQEQWALQQQRQRLY 797
Cdd:PTZ00121 1522 KKADEAKKAEeakkadeAKKAEEKKKADELKKAEELKKAEEKKKaeEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 798 SEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKG-----REEQERRHQMELNTLKQQLELERQAWEAG 872
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKkaeelKKAEEENKIKAAEEAKKAEEDKKKAEEAK 1681
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 873 RTRKERMSPQEAwlLNREQELREEIRKGRDKEielvihrleadmalaKEESEKAAESRIKRLRDKYEAElsELEQSERKL 952
Cdd:PTZ00121 1682 KAEEDEKKAAEA--LKKEAEEAKKAEELKKKE---------------AEEKKKAEELKKAEEENKIKAE--EAKKEAEED 1742
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767994123 953 QERCSELKGQlgeaEGENLRLQGLVRQKERALEDAQAVNEQLSSERsnlaqvIRQEFEDRLAASEEETRQAKAELATLQ 1031
Cdd:PTZ00121 1743 KKKAEEAKKD----EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE------LDEEDEKRRMEVDKKIKDIFDNFANII 1811
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
698-1033 |
8.27e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.62 E-value: 8.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 698 EKTKKIKEVT--VRGLEPEIQKLiarhKQEVRRLKslHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERAR 775
Cdd:TIGR02168 674 ERRREIEELEekIEELEEKIAEL----EKALAELR--KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 776 QRFQQHLEQEQwaLQQQRQRLYSEVAEERERLgqqaarqrAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMEL 855
Cdd:TIGR02168 748 RIAQLSKELTE--LEAEIEELEERLEEAEEEL--------AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 856 NTLKQQLELERQAWEAGRTRkermspqeawllnREQELREEIRKGRDKEIELVIHRLEaDMALAKEESEKAAESrikrlr 935
Cdd:TIGR02168 818 EAANLRERLESLERRIAATE-------------RRLEDLEEQIEELSEDIESLAAEIE-ELEELIEELESELEA------ 877
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 936 dkYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAA 1015
Cdd:TIGR02168 878 --LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE 955
|
330
....*....|....*...
gi 767994123 1016 SEEETRQAKAELATLQAR 1033
Cdd:TIGR02168 956 AEALENKIEDDEEEARRR 973
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
638-1007 |
1.83e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.47 E-value: 1.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 638 IEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKK----LKELMSATEKARREK-----WISEKTKKIKEVTV 708
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKreyeGYELLKEKEALERQKeaierQLASLEEELEKLTE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 709 R--GLEPEIQKLIARHKQEVRRLKSLHEAELL--QSDERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQ 784
Cdd:TIGR02169 259 EisELEKRLEEIEQLLEELNKKIKDLGEEEQLrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEI 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 785 EQWALQQQRQRLysevaeERERLGQQAARQRAELEELRQQLEESSSALtRALRAEFEKGREEQERrHQMELNTLKQqlEL 864
Cdd:TIGR02169 339 EELEREIEEERK------RRDKLTEEYAELKEELEDLRAELEEVDKEF-AETRDELKDYREKLEK-LKREINELKR--EL 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 865 ERQAWEAGRTRKERmspqeawllnreQELREEIRKGRDKEIELVIHRLEADMALAKEESEKaaeSRIKRLRDKYEAELSE 944
Cdd:TIGR02169 409 DRLQEELQRLSEEL------------ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL---EQLAADLSKYEQELYD 473
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767994123 945 LEQSERKLQERCSELKGQLGEAEGEnlrlqglVRQKERALEDAQAVNEQLSSERSNLAQVIRQ 1007
Cdd:TIGR02169 474 LKEEYDRVEKELSKLQRELAEAEAQ-------ARASEERVRGGRAVEEVLKASIQGVHGTVAQ 529
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
676-1044 |
1.92e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.09 E-value: 1.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 676 EIKKLKELMSATEKARREkwisektkkIKEVTVRglEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQaeel 755
Cdd:TIGR02169 161 EIAGVAEFDRKKEKALEE---------LEEVEEN--IERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEG---- 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 756 rEQLEREKEALGQQERERARQRfqQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEE----LRQQLEESSSA 831
Cdd:TIGR02169 226 -YELLKEKEALERQKEAIERQL--ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAE 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 832 LTRALRAEFEKGREEQ---ERRHQMELNTLKQQLELERQAWEAGRTRKERMSpqeawLLNREQELREEIRKGRDKeielv 908
Cdd:TIGR02169 303 IASLERSIAEKERELEdaeERLAKLEAEIDKLLAEIEELEREIEEERKRRDK-----LTEEYAELKEELEDLRAE----- 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 909 IHRLEADMALAKEESeKAAESRIkrlrDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQ 988
Cdd:TIGR02169 373 LEEVDKEFAETRDEL-KDYREKL----EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA 447
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767994123 989 AVNEQLSSERSNLAQV---IRQEFEDR---LAASEEETRQAKAELATLQARQQLELEEGEDS 1044
Cdd:TIGR02169 448 LEIKKQEWKLEQLAADlskYEQELYDLkeeYDRVEKELSKLQRELAEAEAQARASEERVRGG 509
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
605-899 |
7.19e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 7.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 605 VKETEKALSRqLQRQREHYEATIQ-----RHLAfIDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHEleikK 679
Cdd:TIGR02168 195 LNELERQLKS-LERQAEKAERYKElkaelRELE-LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE----K 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 680 LKELMSatEKARREKWISEKTKKIKEVT--VRGLEPEIQKLIARHKQEVRRLKSLhEAELLQSDERASQRCLRQAEELRE 757
Cdd:TIGR02168 269 LEELRL--EVSELEEEIEELQKELYALAneISRLEQQKQILRERLANLERQLEEL-EAQLEELESKLDELAEELAELEEK 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 758 QLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERerlgQQAARQRAELEELRQQLEESSSALTRA-- 835
Cdd:TIGR02168 346 LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE----LQIASLNNEIERLEARLERLEDRRERLqq 421
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767994123 836 -LRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELREEIRK 899
Cdd:TIGR02168 422 eIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
712-914 |
7.94e-10 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 63.40 E-value: 7.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 712 EPEIQKLIARHKQEVRRLKSLHEAELlqsDERASQRCLRQAEELREQLEREKEALGQQERERAR------QRFQQHLEQE 785
Cdd:COG4913 220 EPDTFEAADALVEHFDDLERAHEALE---DAREQIELLEPIRELAERYAAARERLAELEYLRAAlrlwfaQRRLELLEAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 786 QWALQQQRQRLysevAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERR------HQMELNTLK 859
Cdd:COG4913 297 LEELRAELARL----EAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERerrrarLEALLAALG 372
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767994123 860 QQLELERQAWEAGR----TRKERMSPQEAWLLNREQELREEIRKGRD--KEIELVIHRLEA 914
Cdd:COG4913 373 LPLPASAEEFAALRaeaaALLEALEEELEALEEALAEAEAALRDLRRelRELEAEIASLER 433
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
680-1016 |
8.03e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.15 E-value: 8.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 680 LKELMSATEKARREkwiSEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAEL-LQSDERASQRCLRQAEELREQ 758
Cdd:TIGR02168 195 LNELERQLKSLERQ---AEKAERYKELKAELRELELALLVLRLEELREELEELQEELKeAEEELEELTAELQELEEKLEE 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 759 LEREKEALgQQERERARQRFQQH------LEQEQWALQQQRQRL---YSEVAEERERLGQQ-------AARQRAELEELR 822
Cdd:TIGR02168 272 LRLEVSEL-EEEIEELQKELYALaneisrLEQQKQILRERLANLerqLEELEAQLEELESKldelaeeLAELEEKLEELK 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 823 QQLEESSSALT--RALRAEFEKGREEQERrhqmELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELREEIRKG 900
Cdd:TIGR02168 351 EELESLEAELEelEAELEELESRLEELEE----QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEL 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 901 RDKEIELVIHRLEADMALAKEESEKAAESRIKRlrdkyEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQK 980
Cdd:TIGR02168 427 LKKLEEAELKELQAELEELEEELEELQEELERL-----EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501
|
330 340 350
....*....|....*....|....*....|....*....
gi 767994123 981 ERALEDAQAV---NEQLSSERSNLAQVIRQEFEDRLAAS 1016
Cdd:TIGR02168 502 EGFSEGVKALlknQSGLSGILGVLSELISVDEGYEAAIE 540
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
575-940 |
2.80e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.49 E-value: 2.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 575 RLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAV--V 652
Cdd:COG1196 372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAeeE 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 653 AELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRG----LEPEIQKLIARHKQEVRR 728
Cdd:COG1196 452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaaLLLAGLRGLAGAVAVLIG 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 729 LKSLHEAEL-----------LQSDERASQRC--------------LRQAEELREQLEREKEALGQQERERARQRFQQHLE 783
Cdd:COG1196 532 VEAAYEAALeaalaaalqniVVEDDEVAAAAieylkaakagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 784 QEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLE 863
Cdd:COG1196 612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 864 LERQAWEAGRTRKERMSPQEAWLLNREQELREEIRKGRDKEIELVIHRLE----------ADMALAKEESEKAAESRIKR 933
Cdd:COG1196 692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELleeeelleeeALEELPEPPDLEELERELER 771
|
....*..
gi 767994123 934 LRDKYEA 940
Cdd:COG1196 772 LEREIEA 778
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
776-1047 |
4.05e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 4.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 776 QRFQQHLEQEQWALQQQRqrlYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRaLRAEFEKGREEQERR----- 850
Cdd:TIGR02168 216 KELKAELRELELALLVLR---LEELREELEELQEELKEAEEELEELTAELQELEEKLEE-LRLEVSELEEEIEELqkely 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 851 -HQMELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELREEIrkgrdKEIELVIHRLEADMALAKEESEKAaes 929
Cdd:TIGR02168 292 aLANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEEL-----AELEEKLEELKEELESLEAELEEL--- 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 930 rikrlrdkyEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEF 1009
Cdd:TIGR02168 364 ---------EAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE 434
|
250 260 270
....*....|....*....|....*....|....*...
gi 767994123 1010 EDRLAASEEETRQAKAELATLQARQQLELEEGEDSPRE 1047
Cdd:TIGR02168 435 LKELQAELEELEEELEELQEELERLEEALEELREELEE 472
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
784-1029 |
1.63e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.85 E-value: 1.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 784 QEQWALQQQRQRLYSEVAEERERLgQQAARQRAELEELRQQLEESSSALTRALRAefekgREEQERRHQMELNTLKQQLE 863
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKEL-AALKKEEKALLKQLAALERRIAALARRIRA-----LEQELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 864 LERQAWEAgrtRKERMSPQeawllnreqeLREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELS 943
Cdd:COG4942 94 ELRAELEA---QKEELAEL----------LRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 944 ELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQvIRQEFEDRLAASEEETRQA 1023
Cdd:COG4942 161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQ-EAEELEALIARLEAEAAAA 239
|
....*.
gi 767994123 1024 KAELAT 1029
Cdd:COG4942 240 AERTPA 245
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
584-1036 |
2.20e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.24 E-value: 2.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 584 KQAMLLLQRALAQQRDLTARRVKETEKALsRQLQRQREHYEATIQRhLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCT 663
Cdd:COG4717 52 EKEADELFKPQGRKPELNLKELKELEEEL-KEAEEKEEEYAELQEE-LEELEEELEELEAELEELREELEKLEKLLQLLP 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 664 ERVAQAQAQHELE--IKKLKELmsateKARREKWISektkkiKEVTVRGLEPEIQKLiARHKQEVRRLKSLHEAELLQSD 741
Cdd:COG4717 130 LYQELEALEAELAelPERLEEL-----EERLEELRE------LEEELEELEAELAEL-QEELEELLEQLSLATEEELQDL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 742 ERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQ--RLYSEVAEERERLGQQAARQRAELE 819
Cdd:COG4717 198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllLIAAALLALLGLGGSLLSLILTIAG 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 820 ELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQlelERQAWEAGRTRKERMSPQEA-WLLNREQELREEIR 898
Cdd:COG4717 278 VLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEE---ELEELLAALGLPPDLSPEELlELLDRIEELQELLR 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 899 KGRDKEIELVIHRLE----ADMALAKEESEKAAESRIKRLRdKYEAELSELEQSERKLQERCSELKGQLGEAEGENL--R 972
Cdd:COG4717 355 EAEELEEELQLEELEqeiaALLAEAGVEDEEELRAALEQAE-EYQELKEELEELEEQLEELLGELEELLEALDEEELeeE 433
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767994123 973 LQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQL 1036
Cdd:COG4717 434 LEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKL 497
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
631-1033 |
2.46e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.24 E-value: 2.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 631 LAFIDQLIEDKkvlsekCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREkwISEKTKKIKEVtvRG 710
Cdd:COG4717 40 LAFIRAMLLER------LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEE--LEELEEELEEL--EA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 711 LEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALgqQERERARQRFQQHLEQEQWALQ 790
Cdd:COG4717 110 ELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEEL--EELEAELAELQEELEELLEQLS 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 791 QQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTR------------------------------------ 834
Cdd:COG4717 188 LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQleneleaaaleerlkearlllliaaallallglggs 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 835 -------------------ALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTR---KERMSPQEA-WLLNREQ 891
Cdd:COG4717 268 llsliltiagvlflvlgllALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAlglPPDLSPEELlELLDRIE 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 892 ELREEIRKGRDKEIELVIHRLE----ADMALAKEESEKAAESRIKRLRdKYEAELSELEQSERKLQERCSELKGQLGEAE 967
Cdd:COG4717 348 ELQELLREAEELEEELQLEELEqeiaALLAEAGVEDEEELRAALEQAE-EYQELKEELEELEEQLEELLGELEELLEALD 426
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767994123 968 GENLRLQglVRQKERALEDAQAVNEQLSSERSNLAQVIRQ-EFEDRLAASEEETRQAKAELATLQAR 1033
Cdd:COG4717 427 EEELEEE--LEELEEELEELEEELEELREELAELEAELEQlEEDGELAELLQELEELKAELRELAEE 491
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
604-907 |
3.72e-08 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 57.44 E-value: 3.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 604 RVKETEKALSRQLQRQREHYEATIQRHLAFIDQ--LIEDKKVLSEKCEAVVAELKQED-QRCTERVAQAQAQheLEIKKL 680
Cdd:pfam17380 300 RLRQEKEEKAREVERRRKLEEAEKARQAEMDRQaaIYAEQERMAMERERELERIRQEErKRELERIRQEEIA--MEISRM 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 681 KEL----MSATEKARREKWISEKTKKIKEvtvrgLEPEIQKLIARHKQEVRRLKSLHE---AELLQSDERASQRCLRQAE 753
Cdd:pfam17380 378 RELerlqMERQQKNERVRQELEAARKVKI-----LEEERQRKIQQQKVEMEQIRAEQEearQREVRRLEEERAREMERVR 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 754 ELREQLEREKEALGQQERERARQRFQQHLEQEQWAL-QQQRQRLYSEVAEERERLGQQAARQRAELEelrQQLEESSSAL 832
Cdd:pfam17380 453 LEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRaEEQRRKILEKELEERKQAMIEEERKRKLLE---KEMEERQKAI 529
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767994123 833 TralraefekgrEEQERRHQMELNTLKQQLELERQAWEAGRTRKERMSPQEAwlLNREQELREEIRKGRDKEIEL 907
Cdd:pfam17380 530 Y-----------EEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEA--MEREREMMRQIVESEKARAEY 591
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
537-1048 |
4.08e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 4.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 537 DEMEKSGQDQLDSQQEGWVPEAGPGPLELGSEVSTSvmrlklevEEKKQAMLLLQRALAQQRDLTARRVKETEKAL-SRQ 615
Cdd:PTZ00121 1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKA--------EEAKKKAEDARKAEEARKAEDARKAEEARKAEdAKR 1153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 616 LQRQREHYEAtiqrHLAFIDQLIEDKKVLSEKCEAVVAElKQEDQRCTERVAQAQAQHELE-IKKLKELMSATEKARREK 694
Cdd:PTZ00121 1154 VEIARKAEDA----RKAEEARKAEDAKKAEAARKAEEVR-KAEELRKAEDARKAEAARKAEeERKAEEARKAEDAKKAEA 1228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 695 WISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERA 774
Cdd:PTZ00121 1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAK 1308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 775 RQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRA-LRAEFEKGREEQERRHQM 853
Cdd:PTZ00121 1309 KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAeKKKEEAKKKADAAKKKAE 1388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 854 ElntLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKR 933
Cdd:PTZ00121 1389 E---KKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 934 LRDKYEAELSELEQSERKlqeRCSELKGQLGEAEGENLRLQGLVRQKERAlEDAQAVNEQLSSERSNLAQVIRQEFEDRL 1013
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAK---KADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAKKADEAKK 1541
|
490 500 510
....*....|....*....|....*....|....*
gi 767994123 1014 AaseEETRQAKAELATLQARQQLELEEGEDSPREE 1048
Cdd:PTZ00121 1542 A---EEKKKADELKKAEELKKAEEKKKAEEAKKAE 1573
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
772-1040 |
4.45e-08 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 57.44 E-value: 4.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 772 ERARQRFQQHLEQEQwaLQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRAL---RAEFEKGREEQE 848
Cdd:pfam17380 286 ERQQQEKFEKMEQER--LRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMEREReleRIRQEERKRELE 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 849 RRHQMELNT-LKQQLELERQAWEAGRTRKERMSPQEAwllNREQELREEIRKGRDKEielvihrLEADMALAKEESEKAA 927
Cdd:pfam17380 364 RIRQEEIAMeISRMRELERLQMERQQKNERVRQELEA---ARKVKILEEERQRKIQQ-------QKVEMEQIRAEQEEAR 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 928 ESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSER-------SN 1000
Cdd:pfam17380 434 QREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERkqamieeER 513
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 767994123 1001 LAQVIRQEFEDRLAASEEETRQAKAElatLQARQQLELEE 1040
Cdd:pfam17380 514 KRKLLEKEMEERQKAIYEEERRREAE---EERRKQQEMEE 550
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
729-928 |
8.11e-08 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 56.32 E-value: 8.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 729 LKSLHEAELLQSDERAsQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLysevaEERErlg 808
Cdd:PRK12704 25 RKKIAEAKIKEAEEEA-KRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRL-----LQKE--- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 809 QQAARQRAELEELRQQLEESSSALTRaLRAEFEKGREEQERRHQmelntlKQQLELERQAweagrtrkeRMSPQEAwlln 888
Cdd:PRK12704 96 ENLDRKLELLEKREEELEKKEKELEQ-KQQELEKKEEELEELIE------EQLQELERIS---------GLTAEEA---- 155
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 767994123 889 rEQELREEIRKGRDKEIELVIHRLEADmalAKEESEKAAE 928
Cdd:PRK12704 156 -KEILLEKVEEEARHEAAVLIKEIEEE---AKEEADKKAK 191
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1043 |
9.86e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 56.23 E-value: 9.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 610 KALSRQLQRQREHYEATIQRHlAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAqhelEIKKLKELMSATEK 689
Cdd:PRK03918 168 GEVIKEIKRRIERLEKFIKRT-ENIEELIKEKEKELEEVLREINEISSELPELREELEKLEK----EVKELEELKEEIEE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 690 ARREKWISEKTKKIKEVTVRGLEPEIQKLIARHK---QEVRRLKSLHEAEllqsderasqrclrqaeelreqlerekeal 766
Cdd:PRK03918 243 LEKELESLEGSKRKLEEKIRELEERIEELKKEIEeleEKVKELKELKEKA------------------------------ 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 767 gqqERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLgQQAARQRAELEELRQQLEesssaltralraEFEKGREE 846
Cdd:PRK03918 293 ---EEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI-KELEEKEERLEELKKKLK------------ELEKRLEE 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 847 QERRHQmELNTLKQQL-ELERQAWEAGRTRKERMSPQEAWLLNREQELREEIRKGRDKEIELviHRLEADMALAKEESEK 925
Cdd:PRK03918 357 LEERHE-LYEEAKAKKeELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGEL--KKEIKELKKAIEELKK 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 926 A-----------AESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERAledaqavnEQL 994
Cdd:PRK03918 434 AkgkcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELA--------EQL 505
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 767994123 995 SSERSNLAQVIRQEFEdrlaASEEETRQAKAELATLQARQQL---ELEEGED 1043
Cdd:PRK03918 506 KELEEKLKKYNLEELE----KKAEEYEKLKEKLIKLKGEIKSlkkELEKLEE 553
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
576-1049 |
1.93e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.46 E-value: 1.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 576 LKLEVEEKKQAMLLLQ-RALAQQRDLTARRVKETEKALSrQLQRQREHYEATIQRHLAFIDQL----------------- 637
Cdd:TIGR02169 216 LLKEKREYEGYELLKEkEALERQKEAIERQLASLEEELE-KLTEEISELEKRLEEIEQLLEELnkkikdlgeeeqlrvke 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 638 -IEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQ---HELEIKKLKELMsATEKARREKWISEKTKKIKEVTVrgLEP 713
Cdd:TIGR02169 295 kIGELEAEIASLERSIAEKERELEDAEERLAKLEAEidkLLAEIEELEREI-EEERKRRDKLTEEYAELKEELED--LRA 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 714 EIQKLIARHKQEVRRLKSLHEA-ELLQSDERASQRCLRQAEELREQLEREKEALgQQERERARQR---FQQHLEQEQWAL 789
Cdd:TIGR02169 372 ELEEVDKEFAETRDELKDYREKlEKLKREINELKRELDRLQEELQRLSEELADL-NAAIAGIEAKineLEEEKEDKALEI 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 790 QQQRQRLySEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMEL---------NTLKQ 860
Cdd:TIGR02169 451 KKQEWKL-EQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvhGTVAQ 529
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 861 QLELERQ-----------------------AWEAGRTRKERMSPQEAWL-LNREQELREEIRKGR--------------D 902
Cdd:TIGR02169 530 LGSVGERyataievaagnrlnnvvveddavAKEAIELLKRRKAGRATFLpLNKMRDERRDLSILSedgvigfavdlvefD 609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 903 KEIE----------LVIHRLEADMALAKE-----------ESEKAAESRIKRLRDKYEAELSELEQSERkLQERCSELKG 961
Cdd:TIGR02169 610 PKYEpafkyvfgdtLVVEDIEAARRLMGKyrmvtlegelfEKSGAMTGGSRAPRGGILFSRSEPAELQR-LRERLEGLKR 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 962 QLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQ------EFEDRLAASEEETRQAKAELATLQAR-- 1033
Cdd:TIGR02169 689 ELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKlkerleELEEDLSSLEQEIENVKSELKELEARie 768
|
570 580
....*....|....*....|....
gi 767994123 1034 --------QQLELEEGEDSPREEG 1049
Cdd:TIGR02169 769 eleedlhkLEEALNDLEARLSHSR 792
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
770-1037 |
6.11e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 53.69 E-value: 6.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 770 ERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQER 849
Cdd:pfam12128 269 SDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQ 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 850 ----RHQMEL--NTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELREEIRKGRDKEielvihRLEADMALAKEES 923
Cdd:pfam12128 349 lpswQSELENleERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQ------LAVAEDDLQALES 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 924 EkaaesrikrLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLvRQKERALEDAQAVNEQLSSERSNLAQ 1003
Cdd:pfam12128 423 E---------LREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQL-ENFDERIERAREEQEAANAEVERLQS 492
|
250 260 270
....*....|....*....|....*....|....
gi 767994123 1004 VIRQEFEDRLAASEeetRQAKAELATLQARQQLE 1037
Cdd:pfam12128 493 ELRQARKRRDQASE---ALRQASRRLEERQSALD 523
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
764-1040 |
7.50e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 53.58 E-value: 7.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 764 EALGQQERERARQRFQQHlEQEQWALQQQRQRLYSE---VAEERERLGQQAARQRAELEELRQQLEESSSALTRALRaef 840
Cdd:pfam15921 259 ELLLQQHQDRIEQLISEH-EVEITGLTEKASSARSQansIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELR--- 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 841 ekgreEQERRHQMELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELREEIrkgrdkeielviHRLEADMALAK 920
Cdd:pfam15921 335 -----EAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADL------------HKREKELSLEK 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 921 EESekaaesriKRLRDKYEAELSELEQSERKLQERCSE-------LKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQ 993
Cdd:pfam15921 398 EQN--------KRLWDRDTGNSITIDHLRRELDDRNMEvqrlealLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQ 469
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767994123 994 LSSERSNLAQVIRQ--------EFEDR----LAASEEETRQA----KAELATLQARQQLELEE 1040
Cdd:pfam15921 470 LESTKEMLRKVVEEltakkmtlESSERtvsdLTASLQEKERAieatNAEITKLRSRVDLKLQE 532
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
568-955 |
8.46e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.44 E-value: 8.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 568 EVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEK 647
Cdd:pfam02463 633 ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEEL 712
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 648 CEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVR 727
Cdd:pfam02463 713 KKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEK 792
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 728 RLKSLHEAELLQSDERASQRclrQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERErl 807
Cdd:pfam02463 793 EEKLKAQEEELRALEEELKE---EAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE-- 867
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 808 gqqaarQRAELEELRQQLEESssaltRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKERMSPQEAWLL 887
Cdd:pfam02463 868 ------LLQELLLKEEELEEQ-----KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEE 936
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767994123 888 NREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQER 955
Cdd:pfam02463 937 PEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEK 1004
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
568-863 |
9.93e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.14 E-value: 9.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 568 EVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQR-----HLAFIDQLIEDKK 642
Cdd:TIGR02168 702 ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIeeleeRLEEAEEELAEAE 781
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 643 VLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARH 722
Cdd:TIGR02168 782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 723 KQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQER---ERARQRFQQHLEQEQWALQ---QQRQRL 796
Cdd:TIGR02168 862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRselRRELEELREKLAQLELRLEgleVRIDNL 941
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 797 YSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRA----------EFEkgrEEQERR----HQME-LNTLKQQ 861
Cdd:TIGR02168 942 QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaaieEYE---ELKERYdfltAQKEdLTEAKET 1018
|
..
gi 767994123 862 LE 863
Cdd:TIGR02168 1019 LE 1020
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
580-1037 |
1.04e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 580 VEEKKQAMLLLQ-RALAQQRDLTARRVKETEKALSR----QLQRQREHYEATIQRHLAFIDQLIEDKkvlsEKCEAVVAE 654
Cdd:COG4913 245 EDAREQIELLEPiRELAERYAAARERLAELEYLRAAlrlwFAQRRLELLEAELEELRAELARLEAEL----ERLEARLDA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 655 LKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKW--ISEKTKKIkEVTVRGLEPEIQKLIARHKQEVRRLKSL 732
Cdd:COG4913 321 LREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRarLEALLAAL-GLPLPASAEEFAALRAEAAALLEALEEE 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 733 HEAelLQSDERASQRCLRQAEELREQLEREKEALGQ------QERERARQRFQQHL------------------EQEQW- 787
Cdd:COG4913 400 LEA--LEEALAEAEAALRDLRRELRELEAEIASLERrksnipARLLALRDALAEALgldeaelpfvgelievrpEEERWr 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 788 -----ALQQQRQRL------YSEVAE--ERERLGQ------------QAARQRAELEELRQQLEESSSALTRALRAEFEK 842
Cdd:COG4913 478 gaierVLGGFALTLlvppehYAAALRwvNRLHLRGrlvyervrtglpDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGR 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 843 GR-------EEQERRHQMELnTLKQQLELERQAWEAGRTRKERmspqEAWLL---NREQ--ELREEIRkgrdkEIELVIH 910
Cdd:COG4913 558 RFdyvcvdsPEELRRHPRAI-TRAGQVKGNGTRHEKDDRRRIR----SRYVLgfdNRAKlaALEAELA-----ELEEELA 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 911 RLEADMALAKEESE----------------------KAAESRIKRLRDKYEA------ELSELEQSERKLQERCSELKGQ 962
Cdd:COG4913 628 EAEERLEALEAELDalqerrealqrlaeyswdeidvASAEREIAELEAELERldassdDLAALEEQLEELEAELEELEEE 707
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767994123 963 LGEAEGENLRLQglvRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLE 1037
Cdd:COG4913 708 LDELKGEIGRLE---KELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALR 779
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
714-1048 |
1.43e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.76 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 714 EIQKLIARHKQEVRRLKSlHEAELLQSDERASQRclrqaeelreQLEREKEALGQQERERARQRFQQHLEQEQWALQQQR 793
Cdd:TIGR02169 685 GLKRELSSLQSELRRIEN-RLDELSQELSDASRK----------IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 794 QRLYSEVAEERERLgqqaARQRAELEELRQQLEEsssaltraLRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAgr 873
Cdd:TIGR02169 754 ENVKSELKELEARI----EELEEDLHKLEEALND--------LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQ-- 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 874 tRKERMSPQEAWLLNREQELREEIR--KGRDKEIELVIHRLEADMAlAKEESEKAAESRIKRLRDKY---EAELSELEQS 948
Cdd:TIGR02169 820 -KLNRLTLEKEYLEKEIQELQEQRIdlKEQIKSIEKEIENLNGKKE-ELEEELEELEAALRDLESRLgdlKKERDELEAQ 897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 949 ERKLQERCSELKGQLGEAEGENLRLQ---GLVRQKERALEDAQAVNEQLSSERSNLAQV--IRQEFEDRLAASEEETRQA 1023
Cdd:TIGR02169 898 LRELERKIEELEAQIEKKRKRLSELKaklEALEEELSEIEDPKGEDEEIPEEELSLEDVqaELQRVEEEIRALEPVNMLA 977
|
330 340
....*....|....*....|....*
gi 767994123 1024 KAELATLQARqQLELEEGEDSPREE 1048
Cdd:TIGR02169 978 IQEYEEVLKR-LDELKEKRAKLEEE 1001
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
576-1048 |
1.71e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.28 E-value: 1.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 576 LKLEVEEKKQamLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAEL 655
Cdd:TIGR00618 158 LKAKSKEKKE--LLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREAL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 656 KQEDQrctervAQAQAQHELEikklkelmSATEKARREKWISEKTKKIKEVtvRGLEPEIQKLIARHKQEVRRLKSLHEA 735
Cdd:TIGR00618 236 QQTQQ------SHAYLTQKRE--------AQEEQLKKQQLLKQLRARIEEL--RAQEAVLEETQERINRARKAAPLAAHI 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 736 ELLQSDERASQRCLRQaeelreqlerekeaLGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQR 815
Cdd:TIGR00618 300 KAVTQIEQQAQRIHTE--------------LQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVAT 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 816 AELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELRE 895
Cdd:TIGR00618 366 SIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAA 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 896 EIRKGRDKEIELVIHRLEADMAL-AKEESEKAAES---RIKRLRDKYEAELSELEQSERKLQERCSELKG---QLGEAEG 968
Cdd:TIGR00618 446 AITCTAQCEKLEKIHLQESAQSLkEREQQLQTKEQihlQETRKKAVVLARLLELQEEPCPLCGSCIHPNParqDIDNPGP 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 969 ENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFE--DRLAASEEETRQAKAELATLQARQQLELEEGEDSPR 1046
Cdd:TIGR00618 526 LTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEiqQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSE 605
|
..
gi 767994123 1047 EE 1048
Cdd:TIGR00618 606 AE 607
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
799-1033 |
1.97e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 51.96 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 799 EVAEERErlgQQAARQRAELEELRQQLEESSSALTRALRAEfekgreEQERRhqmeLNTLKQQLELERQAWEAGRTRKER 878
Cdd:PRK02224 468 ETIEEDR---ERVEELEAELEDLEEEVEEVEERLERAEDLV------EAEDR----IERLEERREDLEELIAERRETIEE 534
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 879 MSPQEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAA-ESRIKRLrDKYEAELSELEQSERKLQERCS 957
Cdd:PRK02224 535 KRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAElKERIESL-ERIRTLLAAIADAEDEIERLRE 613
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767994123 958 ELKGQlgeAEGENLRLQGLVRQKERALEDAQAVNEqlssERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQAR 1033
Cdd:PRK02224 614 KREAL---AELNDERRERLAEKRERKRELEAEFDE----ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAE 682
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
795-1056 |
1.99e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.99 E-value: 1.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 795 RLYSEVAEERERLGQ---QAARQRAELEELRQQLEESSSALTRA--------LRAEFEKGREEQERRHQMELNTLKQQLE 863
Cdd:TIGR02169 671 SEPAELQRLRERLEGlkrELSSLQSELRRIENRLDELSQELSDAsrkigeieKEIEQLEQEEEKLKERLEELEEDLSSLE 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 864 LERQAWEAGRTRKE-RMSPQEAWLLNREQELREEIRKGRDKEIELVIHRLEadmalAKEESEKAAESRIKRLRDKYEAEL 942
Cdd:TIGR02169 751 QEIENVKSELKELEaRIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS-----KLEEEVSRIEARLREIEQKLNRLT 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 943 SELEQSERK---LQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRqEFEDRLAASEEE 1019
Cdd:TIGR02169 826 LEKEYLEKEiqeLQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD-ELEAQLRELERK 904
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 767994123 1020 TRQAKAELATLQARQ-----QLELEEGEDSPREEGGGREQPP 1056
Cdd:TIGR02169 905 IEELEAQIEKKRKRLselkaKLEALEEELSEIEDPKGEDEEI 946
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
595-1054 |
2.84e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 51.71 E-value: 2.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 595 AQQRDLTARRVKETEKaLSRQLQRQREHYEATI----QRHLAFIDQLIED------KKVLSEKCEAVVAELKQEDQRCTE 664
Cdd:pfam01576 316 AAQQELRSKREQEVTE-LKKALEEETRSHEAQLqemrQKHTQALEELTEQleqakrNKANLEKAKQALESENAELQAELR 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 665 RVAQAQAQHELEIKK----LKELMSATEKARREKW-ISEKTKKIKEV--TVRGLEPEIQKLIARHKQEVRRLKS-LHEA- 735
Cdd:pfam01576 395 TLQQAKQDSEHKRKKlegqLQELQARLSESERQRAeLAEKLSKLQSEleSVSSLLNEAEGKNIKLSKDVSSLESqLQDTq 474
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 736 ELLQSDERASQRCLRQAEELREQLEREKEALgqQERERARQRFQQHLEQEQWALQQQRQRLySEVAEERERLGQQAARQR 815
Cdd:pfam01576 475 ELLQEETRQKLNLSTRLRQLEDERNSLQEQL--EEEEEAKRNVERQLSTLQAQLSDMKKKL-EEDAGTLEALEEGKKRLQ 551
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 816 AELEELRQQLEESSSALTRAlraefekgrEEQERRHQMELNTLKQQLELERQ---AWEAGRTRKERMSPQEAWLLNREQE 892
Cdd:pfam01576 552 RELEALTQQLEEKAAAYDKL---------EKTKNRLQQELDDLLVDLDHQRQlvsNLEKKQKKFDQMLAEEKAISARYAE 622
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 893 LREEI-RKGRDKEIE-LVIHRLEADMALAKEESEKAAesriKRLRDKYEAELS----------ELEQSERKLQERCSELK 960
Cdd:pfam01576 623 ERDRAeAEAREKETRaLSLARALEEALEAKEELERTN----KQLRAEMEDLVSskddvgknvhELERSKRALEQQVEEMK 698
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 961 GQLGEAEGE-------NLRL----QGLVRQKERaleDAQAVNEQLSSERSNLAQVIRQefedrLAASEEETRQAKAELAT 1029
Cdd:pfam01576 699 TQLEELEDElqatedaKLRLevnmQALKAQFER---DLQARDEQGEEKRRQLVKQVRE-----LEAELEDERKQRAQAVA 770
|
490 500
....*....|....*....|....*
gi 767994123 1030 LQARQQLELEEGEDSPREEGGGREQ 1054
Cdd:pfam01576 771 AKKKLELDLKELEAQIDAANKGREE 795
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
652-1035 |
3.22e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 51.59 E-value: 3.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 652 VAELKQEDQRCT---ERVAQAQAQHELEIKKL--KELMSATEKARREKWISEKTKKIKEVTvrGLEPEIQKLIARHKQEV 726
Cdd:TIGR00606 669 ITQLTDENQSCCpvcQRVFQTEAELQEFISDLqsKLRLAPDKLKSTESELKKKEKRRDEML--GLAPGRQSIIDLKEKEI 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 727 RRLKslheaELLQSDERASQRclrqaeelreqlerEKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERER 806
Cdd:TIGR00606 747 PELR-----NKLQKVNRDIQR--------------LKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERK 807
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 807 LGQQAARQRA-----ELEELRQQLEESSSALTRALRAEFEKGREEQERRHQME-LNTLKQQLELERQAWEAGRTRKERMS 880
Cdd:TIGR00606 808 IAQQAAKLQGsdldrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQhLKSKTNELKSEKLQIGTNLQRRQQFE 887
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 881 PQEAWLLNREQELREEIRKGRDKEIELV-----IHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQER 955
Cdd:TIGR00606 888 EQLVELSTEVQSLIREIKDAKEQDSPLEtflekDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDG 967
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 956 CSE-LKGQLGEAEGENLRLQGLVRQKERALED----AQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATL 1030
Cdd:TIGR00606 968 KDDyLKQKETELNTVNAQLEECEKHQEKINEDmrlmRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQM 1047
|
....*
gi 767994123 1031 QARQQ 1035
Cdd:TIGR00606 1048 QVLQM 1052
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
574-1054 |
4.31e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.94 E-value: 4.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 574 MRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFI-------DQLIEDKKVLSE 646
Cdd:pfam01576 80 LESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDIllledqnSKLSKERKLLEE 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 647 KCEAVVAELKQEDQRcTERVAQAQAQHELEIKKLKELMSATEKARREkwiSEKTKKIKEvtvrGLEPEIQKLIARHKQEV 726
Cdd:pfam01576 160 RISEFTSNLAEEEEK-AKSLSKLKNKHEAMISDLEERLKKEEKGRQE---LEKAKRKLE----GESTDLQEQIAELQAQI 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 727 RRLKslheAELLQSDERasqrcLRQAEELREQLEREKEALGQQERErarqrFQQHLEQEQWALQQQRQrlYSEVAEERER 806
Cdd:pfam01576 232 AELR----AQLAKKEEE-----LQAALARLEEETAQKNNALKKIRE-----LEAQISELQEDLESERA--ARNKAEKQRR 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 807 -LGQQAARQRAELE----------ELRQQLEESSSALTRALRAE---FEKGREEQERRHQMELNTLKQQLELERQAweag 872
Cdd:pfam01576 296 dLGEELEALKTELEdtldttaaqqELRSKREQEVTELKKALEEEtrsHEAQLQEMRQKHTQALEELTEQLEQAKRN---- 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 873 rtrKERMSPQEAWLLNREQELREEIRKgrdkeielvihrleadMALAKEESE---KAAESRIKRLRDKY-EAELSELEQS 948
Cdd:pfam01576 372 ---KANLEKAKQALESENAELQAELRT----------------LQQAKQDSEhkrKKLEGQLQELQARLsESERQRAELA 432
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 949 ER--KLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDR------LAASEEET 1020
Cdd:pfam01576 433 EKlsKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERnslqeqLEEEEEAK 512
|
490 500 510
....*....|....*....|....*....|....*....
gi 767994123 1021 RQAKAELATLQA-----RQQLELEEGEDSPREEGGGREQ 1054
Cdd:pfam01576 513 RNVERQLSTLQAqlsdmKKKLEEDAGTLEALEEGKKRLQ 551
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
763-1054 |
5.01e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 50.73 E-value: 5.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 763 KEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQR--AELEELRQQLEESSSAltRALRAEF 840
Cdd:PRK04863 300 RQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERyqADLEELEERLEEQNEV--VEEADEQ 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 841 EKGREEQERRHQMELNTLKQQLELERQAWEAGRTR-------KERMSPQEAWLLNREQE---LREEIRKGRDKEIELVIH 910
Cdd:PRK04863 378 QEENEARAEAAEEEVDELKSQLADYQQALDVQQTRaiqyqqaVQALERAKQLCGLPDLTadnAEDWLEEFQAKEQEATEE 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 911 RLEADMAL-----AKEESEKAAESrIKRLRDkyEAELSELEQSERKLQERCSELKGQLGeaegenlRLQGLvRQKERALE 985
Cdd:PRK04863 458 LLSLEQKLsvaqaAHSQFEQAYQL-VRKIAG--EVSRSEAWDVARELLRRLREQRHLAE-------QLQQL-RMRLSELE 526
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767994123 986 daQAVNEQLSSERsnlaqvIRQEFEDRLAASEeetrQAKAELATLQARQQLELEEGEDSPREEGGGREQ 1054
Cdd:PRK04863 527 --QRLRQQQRAER------LLAEFCKRLGKNL----DDEDELEQLQEELEARLESLSESVSEARERRMA 583
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
764-1039 |
5.15e-06 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 50.72 E-value: 5.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 764 EALGQQErerARQRFQQHLEQEQWALQQQRQRLySEVAEERERLGQQAARQRAELEELRQQLEESSSAL----TRA---- 835
Cdd:COG3096 341 TALRQQE---KIERYQEDLEELTERLEEQEEVV-EEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALdvqqTRAiqyq 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 836 -----------------LRAEFEKGREEQERRHQMELNT----LKQQL----------------------ELER-QAWEA 871
Cdd:COG3096 417 qavqalekaralcglpdLTPENAEDYLAAFRAKEQQATEevleLEQKLsvadaarrqfekayelvckiagEVERsQAWQT 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 872 GRTRKERMSPQEAwLLNREQELREEIRkgrdkEIELVIHRLEADMALAKEESEKAAESR-----IKRLRDKYEAELSELE 946
Cdd:COG3096 497 ARELLRRYRSQQA-LAQRLQQLRAQLA-----ELEQRLRQQQNAERLLEEFCQRIGQQLdaaeeLEELLAELEAQLEELE 570
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 947 QSERKLQERCSELKGQLGEAEGENLRLqglvRQKERALEDAQAVNEQLSSERS----NLAQVirQEFEDRLAASEEETRQ 1022
Cdd:COG3096 571 EQAAEAVEQRSELRQQLEQLRARIKEL----AARAPAWLAAQDALERLREQSGealaDSQEV--TAAMQQLLEREREATV 644
|
330
....*....|....*..
gi 767994123 1023 AKAELAtlQARQQLELE 1039
Cdd:COG3096 645 ERDELA--ARKQALESQ 659
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
576-1040 |
5.34e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 50.74 E-value: 5.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 576 LKLEVEEKKQAMLLLQRALAQQRDLTARRvkeTEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAE- 654
Cdd:TIGR00618 403 DILQREQATIDTRTSAFRDLQGQLAHAKK---QQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKe 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 655 --LKQEDQRCTERVAQAQAQHELEiKKLKELMSATEKARREKWISEKTKKI---KEVTVRGLEPEIQKLIARHKQEVRRL 729
Cdd:TIGR00618 480 qiHLQETRKKAVVLARLLELQEEP-CPLCGSCIHPNPARQDIDNPGPLTRRmqrGEQTYAQLETSEEDVYHQLTSERKQR 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 730 KSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQ-----QERERARQRFQQHLEQEQWALQQQRQRLYSEVAEER 804
Cdd:TIGR00618 559 ASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQdltekLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCS 638
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 805 ERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAgrTRKERMSPQEA 884
Cdd:TIGR00618 639 QELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTL--LRELETHIEEY 716
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 885 WLLNREQELREEIRK----GRDKEIELVIHRLEADMALAKEESEKAAESRIKRL--RDKYEAELSELEQSERKLQERCSE 958
Cdd:TIGR00618 717 DREFNEIENASSSLGsdlaAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVtaALQTGAELSHLAAEIQFFNRLREE 796
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 959 LKGQLGEAEGENLR-----LQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDrlaaseEETRQAKAELATLQAR 1033
Cdd:TIGR00618 797 DTHLLKTLEAEIGQeipsdEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKY------EECSKQLAQLTQEQAK 870
|
....*..
gi 767994123 1034 QQLELEE 1040
Cdd:TIGR00618 871 IIQLSDK 877
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
603-1047 |
7.22e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 7.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 603 RRVKETEKALSR--QLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRcTERVAQAQAQHEL---EI 677
Cdd:PRK03918 176 RRIERLEKFIKRteNIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL-KEEIEELEKELESlegSK 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 678 KKLKELMSATEKARRE--KWISEKTKKIKEVT-VRGLEPEIQKLIARHKQEVRRLKSLH-EAELLQSDERASQRCLRQAE 753
Cdd:PRK03918 255 RKLEEKIRELEERIEElkKEIEELEEKVKELKeLKEKAEEYIKLSEFYEEYLDELREIEkRLSRLEEEINGIEERIKELE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 754 ELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYS----------------------EVAEERERLGQQA 811
Cdd:PRK03918 335 EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKrltgltpeklekeleelekakeEIEEEISKITARI 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 812 ARQRAELEELRQQLEESSSALTRAL---RAEFEKGREEQERRHQMELNTLKQQL----ELERQAWEagRTRKERMSPQEA 884
Cdd:PRK03918 415 GELKKEIKELKKAIEELKKAKGKCPvcgRELTEEHRKELLEEYTAELKRIEKELkeieEKERKLRK--ELRELEKVLKKE 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 885 WLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAA--ESRIKRLRDK------YEAELSELEQSERKLQERC 956
Cdd:PRK03918 493 SELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIklKGEIKSLKKElekleeLKKKLAELEKKLDELEEEL 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 957 SELKGQLGE------------------AEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQV-------------I 1005
Cdd:PRK03918 573 AELLKELEElgfesveeleerlkelepFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETekrleelrkeleeL 652
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 767994123 1006 RQEF-EDRLAASEEETRQAKAELATLQARqqleLEEGEDSPRE 1047
Cdd:PRK03918 653 EKKYsEEEYEELREEYLELSRELAGLRAE----LEELEKRREE 691
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
769-960 |
7.88e-06 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 50.01 E-value: 7.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 769 QERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALT--RALRAEFEKGREE 846
Cdd:PHA02562 194 QQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNklNTAAAKIKSKIEQ 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 847 QERRHQM-----ELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELRE---EIRKGRDKEIELV--IHRLEADM 916
Cdd:PHA02562 274 FQKVIKMyekggVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEimdEFNEQSKKLLELKnkISTNKQSL 353
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 767994123 917 ALAKEESeKAAESRIKRLRDK---YEAELSELEQSERKLQERCSELK 960
Cdd:PHA02562 354 ITLVDKA-KKVKAAIEELQAEfvdNAEELAKLQDELDKIVKTKSELV 399
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
604-1043 |
8.47e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 50.12 E-value: 8.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 604 RVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKV----LSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKK 679
Cdd:pfam15921 239 RIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVeitgLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 680 LKELMSATEKARREKwisEKTKKIKEVTVRGLEPEIQkLIARHKQEVRRLKSLHEAELLQSDERAsQRCLRQAEELREQL 759
Cdd:pfam15921 319 LSDLESTVSQLRSEL---REAKRMYEDKIEELEKQLV-LANSELTEARTERDQFSQESGNLDDQL-QKLLADLHKREKEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 760 EREKEALGQ-QERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSaLTRALRA 838
Cdd:pfam15921 394 SLEKEQNKRlWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSS-LTAQLES 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 839 EFEKGRE--EQERRHQMELNT-------LKQQLELERQAWEAG-------RTRKERMSPQEAWLLNREQELR------EE 896
Cdd:pfam15921 473 TKEMLRKvvEELTAKKMTLESsertvsdLTASLQEKERAIEATnaeitklRSRVDLKLQELQHLKNEGDHLRnvqtecEA 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 897 IR---KGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYE-----AELSELEQSERKLQERCSELKGQLGEAEG 968
Cdd:pfam15921 553 LKlqmAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEindrrLELQEFKILKDKKDAKIRELEARVSDLEL 632
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 969 ENLRLQGLVRQKERALEDAQAVNEQLSSE----RSNLA------QVIRQEFEDRLAASEEETRQAKAELATLQA-----R 1033
Cdd:pfam15921 633 EKVKLVNAGSERLRAVKDIKQERDQLLNEvktsRNELNslsedyEVLKRNFRNKSEEMETTTNKLKMQLKSAQSeleqtR 712
|
490
....*....|
gi 767994123 1034 QQLELEEGED 1043
Cdd:pfam15921 713 NTLKSMEGSD 722
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
567-1012 |
8.59e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 8.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 567 SEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLtarrvkETEKALSRQLQRQREHYEAtIQRHLAFIDQLIEDKKVLSE 646
Cdd:COG4717 98 EELEEELEELEAELEELREELEKLEKLLQLLPLY------QELEALEAELAELPERLEE-LEERLEELRELEEELEELEA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 647 KCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSA--TEKARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQ 724
Cdd:COG4717 171 ELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAEleEELEEAQEELEELEEELEQLENELEAAALEERLKEARL 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 725 EVRRLKSLHEAELLQSDERASQR--------CLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWAlqqqrqrl 796
Cdd:COG4717 251 LLLIAAALLALLGLGGSLLSLILtiagvlflVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELE-------- 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 797 ysevaEERERLGQQAARQRAELEELRQQLEEsssaltraLRAEFEKGREEQERRHQMELNTLKQQLelerqaWEAGRTRK 876
Cdd:COG4717 323 -----ELLAALGLPPDLSPEELLELLDRIEE--------LQELLREAEELEEELQLEELEQEIAAL------LAEAGVED 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 877 ERMSPQEAWLLNREQELREEIrkgrdkeiELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERC 956
Cdd:COG4717 384 EEELRAALEQAEEYQELKEEL--------EELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREEL 455
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 767994123 957 SELKGQLGEAEGENlRLQGLVRQKERALEDAQAVNEQLSSER--SNLAQVIRQEFEDR 1012
Cdd:COG4717 456 AELEAELEQLEEDG-ELAELLQELEELKAELRELAEEWAALKlaLELLEEAREEYREE 512
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
567-1042 |
8.76e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.06 E-value: 8.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 567 SEVSTSVMRLKLEVEEKKQAMLLLQRAL----AQQRDLTaRRVKETEKALsRQLQRQREHYEATIQRHLAFIDQLIEDKK 642
Cdd:TIGR02168 263 QELEEKLEELRLEVSELEEEIEELQKELyalaNEISRLE-QQKQILRERL-ANLERQLEELEAQLEELESKLDELAEELA 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 643 VLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELmsaTEKARREKWISEKTKKIKEvTVRGLEPEIQKLIARH 722
Cdd:TIGR02168 341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL---ETLRSKVAQLELQIASLNN-EIERLEARLERLEDRR 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 723 KQEVRRLKSlHEAELLQSDERASQRCLRQAEELREQLEREKEALgQQERERARQRFQQhLEQEQWALQQQRQRLYSEVAE 802
Cdd:TIGR02168 417 ERLQQEIEE-LLKKLEEAELKELQAELEELEEELEELQEELERL-EEALEELREELEE-AEQALDAAERELAQLQARLDS 493
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 803 ERERLGQQAARQRAELEELRQQL----------------EESSSALTRALRA-----------------EFEKgREEQER 849
Cdd:TIGR02168 494 LERLQENLEGFSEGVKALLKNQSglsgilgvlselisvdEGYEAAIEAALGGrlqavvvenlnaakkaiAFLK-QNELGR 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 850 RHQMELNTLKQQL----ELERQAWEAG--------RTRKERMSPQEAWLLNR---EQELREEIRKGRDKEIELVIHRLEA 914
Cdd:TIGR02168 573 VTFLPLDSIKGTEiqgnDREILKNIEGflgvakdlVKFDPKLRKALSYLLGGvlvVDDLDNALELAKKLRPGYRIVTLDG 652
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 915 DMALAK----EESEKAAESRIKRlrdkyEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAV 990
Cdd:TIGR02168 653 DLVRPGgvitGGSAKTNSSILER-----RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 767994123 991 NEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEGE 1042
Cdd:TIGR02168 728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
699-1054 |
3.12e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.84 E-value: 3.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 699 KTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALgqQERERARQRF 778
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY--QELEALEAEL 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 779 QQhlEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQmELNTL 858
Cdd:COG4717 142 AE--LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEE-ELEEA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 859 KQQLELERQAWEAGRTRKERMSPQEAWLLNRE-------------QELREEIRKGRDKEIELVIHRLEADMALAKEESEK 925
Cdd:COG4717 219 QEELEELEEELEQLENELEAAALEERLKEARLllliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKA 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 926 AAESRIKRLRDkyEAELSELEQSERKLQERCSELKGQLGEAEGENL-----RLQGLVRQKERALEDAQAvnEQLSSERSN 1000
Cdd:COG4717 299 SLGKEAEELQA--LPALEELEEEELEELLAALGLPPDLSPEELLELldrieELQELLREAEELEEELQL--EELEQEIAA 374
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 767994123 1001 LAQVIRQEFEDRLAASEEETRQAKAELATL-QARQQLELEEGEDSPREEGGGREQ 1054
Cdd:COG4717 375 LLAEAGVEDEEELRAALEQAEEYQELKEELeELEEQLEELLGELEELLEALDEEE 429
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
855-1048 |
3.34e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 3.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 855 LNTLKQQLE-LERQAWEAgrtrkermspqeawllNREQELREEIRkgrDKEIELVIHRLEA--DMALAKEESEKAAESRI 931
Cdd:TIGR02168 195 LNELERQLKsLERQAEKA----------------ERYKELKAELR---ELELALLVLRLEElrEELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 932 KRLR---DKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQViRQE 1008
Cdd:TIGR02168 256 EELTaelQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK-LDE 334
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 767994123 1009 FEDRLAASEEETRQAKAELATLQAR------QQLELEEGEDSPREE 1048
Cdd:TIGR02168 335 LAEELAELEEKLEELKEELESLEAEleeleaELEELESRLEELEEQ 380
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
794-965 |
3.97e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.07 E-value: 3.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 794 QRLYSEVAEERERLGqqaaRQRAELEELRQQLEESSSALTrALRAEFEKGREEQeRRHQMELNTLKQQLELERQAWEAGR 873
Cdd:COG1579 13 QELDSELDRLEHRLK----ELPAELAELEDELAALEARLE-AAKTELEDLEKEI-KRLELEIEEVEARIKKYEEQLGNVR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 874 TRKERMSpqeawLLNREQELREEIRKGRDKEIELV--IHRLEADMALAKEEsEKAAESRIKRLRDKYEAELSELEQSERK 951
Cdd:COG1579 87 NNKEYEA-----LQKEIESLKRRISDLEDEILELMerIEELEEELAELEAE-LAELEAELEEKKAELDEELAELEAELEE 160
|
170
....*....|....
gi 767994123 952 LQERCSELKGQLGE 965
Cdd:COG1579 161 LEAEREELAAKIPP 174
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
578-959 |
4.05e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 4.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 578 LEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALS------RQLQRQREhyeaTIQRHLAFIDQLIEDKKVLSEKCEAV 651
Cdd:TIGR02169 677 QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSdasrkiGEIEKEIE----QLEQEEEKLKERLEELEEDLSSLEQE 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 652 VAELKQEDQRCTERVaqaqAQHELEIKKLKELMSATEKARREKWISEKTKKIKEvtvrgLEPEIQKLIARHKQEVRRLKS 731
Cdd:TIGR02169 753 IENVKSELKELEARI----EELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK-----LEEEVSRIEARLREIEQKLNR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 732 LHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERErarqRFQQHLEQEQWALQQQRQRLySEVAEERERLgqqa 811
Cdd:TIGR02169 824 LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE----ELEEELEELEAALRDLESRL-GDLKKERDEL---- 894
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 812 arqRAELEELRQQLEESSSALtralraefekgreEQERRHQMELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQ 891
Cdd:TIGR02169 895 ---EAQLRELERKIEELEAQI-------------EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQA 958
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767994123 892 ELReeirkgrdkEIELVIHRLEADMALAKEESEKAAESrikrlRDKYEAELSELEQSERKLQERCSEL 959
Cdd:TIGR02169 959 ELQ---------RVEEEIRALEPVNMLAIQEYEEVLKR-----LDELKEKRAKLEEERKAILERIEEY 1012
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
725-1038 |
1.02e-04 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 46.61 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 725 EVRRLKSLHE-AELLQSDERAS--QRCLRQAEELREQLEREKEALgqqereRARQRFQQHL-------EQEQWALQQQRQ 794
Cdd:COG5022 737 EDMRDAKLDNiATRIQRAIRGRylRRRYLQALKRIKKIQVIQHGF------RLRRLVDYELkwrlfikLQPLLSLLGSRK 810
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 795 RLYSEVAE--------ERERLGQQAARQRAEL--EELRQQLEESSSALTRALR------AEFEKGREEQERRHQMEL--- 855
Cdd:COG5022 811 EYRSYLACiiklqktiKREKKLRETEEVEFSLkaEVLIQKFGRSLKAKKRFSLlkketiYLQSAQRVELAERQLQELkid 890
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 856 ----NTLKQQ-LELERQAWEAGRTRKERMSPQEAWLLNREQELrEEIRKGRDKEIELVIHRLEADmalaKEESEKAAESR 930
Cdd:COG5022 891 vksiSSLKLVnLELESEIIELKKSLSSDLIENLEFKTELIARL-KKLLNNIDLEEGPSIEYVKLP----ELNKLHEVESK 965
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 931 IKRLRDKYEAELSELEQSERKLQERCSELKG---QLGEAEGENLRLQ---GLVRQKERALEDAQAVNEQLSSERSNLAQv 1004
Cdd:COG5022 966 LKETSEEYEDLLKKSTILVREGNKANSELKNfkkELAELSKQYGALQestKQLKELPVEVAELQSASKIISSESTELSI- 1044
|
330 340 350
....*....|....*....|....*....|....
gi 767994123 1005 iRQEFEDRLAASEEETRQAKAELATLQARQQLEL 1038
Cdd:COG5022 1045 -LKPLQKLKGLLLLENNQLQARYKALKLRRENSL 1077
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
666-896 |
1.15e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 666 VAQAQAQHELEiKKLKELMSatEKARREKWISEKTKKIKEvtvrgLEPEIQKLIARHKQEVRRLKSLheaellQSDERAS 745
Cdd:COG4942 16 AAQADAAAEAE-AELEQLQQ--EIAELEKELAALKKEEKA-----LLKQLAALERRIAALARRIRAL------EQELAAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 746 QRCLRQAEELREQLEREKEALGQQ--ERERARQRFQQH------LEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAE 817
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEElaELLRALYRLGRQpplallLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 818 LEELRQQLEESSSALTRALRAEFEKGR--EEQERRHQMELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELRE 895
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAalEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
.
gi 767994123 896 E 896
Cdd:COG4942 242 R 242
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
593-1035 |
1.71e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 45.71 E-value: 1.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 593 ALAQQRDLTARRVKETeKALSRQLQRQREHYEATIQRHLAFidqliedkkVLSEKCEAVVAELKQEDQRCTERVAQAQA- 671
Cdd:COG3096 789 ELRAERDELAEQYAKA-SFDVQKLQRLHQAFSQFVGGHLAV---------AFAPDPEAELAALRQRRSELERELAQHRAq 858
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 672 --QHELEIKKLKELMSAtekarrekwisektkkikevtVRGLEPEIQKLIARHKQEvrRLKSLHE-AELLQSDERASQRC 748
Cdd:COG3096 859 eqQLRQQLDQLKEQLQL---------------------LNKLLPQANLLADETLAD--RLEELREeLDAAQEAQAFIQQH 915
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 749 LRQAEELREQLEREKEALGQQERerarqrFQQHLEQEQWALQQQRQRLY--SEVAEERERLGQQAArqraeleelrQQLE 826
Cdd:COG3096 916 GKALAQLEPLVAVLQSDPEQFEQ------LQADYLQAKEQQRRLKQQIFalSEVVQRRPHFSYEDA----------VGLL 979
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 827 ESSSALTRALRAEFEKGrEEQERRHQMELNTLKQQLELERQAWEAGRTRKErmspqeawllNREQELREEIRkgrdkeie 906
Cdd:COG3096 980 GENSDLNEKLRARLEQA-EEARREAREQLRQAQAQYSQYNQVLASLKSSRD----------AKQQTLQELEQ-------- 1040
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 907 lvihRLEADMALAKEESEKAAESRikrlRDKYEAELSELEQserklqeRCSELKGQLGEAEGENLRLQGLVRQKERaleD 986
Cdd:COG3096 1041 ----ELEELGVQADAEAEERARIR----RDELHEELSQNRS-------RRSQLEKQLTRCEAEMDSLQKRLRKAER---D 1102
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 767994123 987 AQAVNEQLSSERSNLAQVIRqefedRLAASEEETRQAKAELATLQARQQ 1035
Cdd:COG3096 1103 YKQEREQVVQAKAGWCAVLR-----LARDNDVERRLHRRELAYLSADEL 1146
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
903-1005 |
2.06e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 45.46 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 903 KEIELVIHRLEADMALAKEESEKAAESRIKRLRDKY---EAELSELE---QSERKLQERCSELKGQLGEAEGENLRLQGL 976
Cdd:COG0542 414 DELERRLEQLEIEKEALKKEQDEASFERLAELRDELaelEEELEALKarwEAEKELIEEIQELKEELEQRYGKIPELEKE 493
|
90 100 110
....*....|....*....|....*....|
gi 767994123 977 VRQKERALEDAQA-VNEQLSSErsNLAQVI 1005
Cdd:COG0542 494 LAELEEELAELAPlLREEVTEE--DIAEVV 521
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
792-982 |
2.69e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.11 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 792 QRQRLYSEVAEERERLGQQAARQRAELEELRQQLEesssaltrALRAEFEKGREEQErrhqMELNTLKQQLELERQAWEA 871
Cdd:pfam15921 643 ERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE--------VLKRNFRNKSEEME----TTTNKLKMQLKSAQSELEQ 710
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 872 GRTRKERMSPQEAWLLNREQELREEI--RKGRDKEIELVIHRLEADMALA-------KEESEKAAE--SRIKRLRDKYEA 940
Cdd:pfam15921 711 TRNTLKSMEGSDGHAMKVAMGMQKQItaKRGQIDALQSKIQFLEEAMTNAnkekhflKEEKNKLSQelSTVATEKNKMAG 790
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 767994123 941 ELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKER 982
Cdd:pfam15921 791 ELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQ 832
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
770-922 |
3.02e-04 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 44.56 E-value: 3.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 770 ERERARQRFQQHLEQEQwalQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQE- 848
Cdd:pfam15709 351 ERKRREQEEQRRLQQEQ---LERAEKMREELELEQQRRFEEIRLRKQRLEEERQRQEEEERKQRLQLQAAQERARQQQEe 427
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767994123 849 -RRHQMELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEE 922
Cdd:pfam15709 428 fRRKLQELQRKKQQEEAERAEAEKQRQKELEMQLAEEQKRLMEMAEEERLEYQRQKQEAEEKARLEAEERRQKEE 502
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
789-983 |
3.17e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 3.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 789 LQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEE--SSSALTRAlrAEFEKGREEQERRHQMELNTLKQQLELER 866
Cdd:COG3206 162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDL--SEEAKLLLQQLSELESQLAEARAELAEAE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 867 QAWEAGRTRKERMSPQEAWLLN--REQELREEIRKGRDKEIEL---------VIHRLEADMAlakeESEKAAESRIKRLR 935
Cdd:COG3206 240 ARLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELsarytpnhpDVIALRAQIA----ALRAQLQQEAQRIL 315
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 767994123 936 DKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERA 983
Cdd:COG3206 316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVA 363
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
768-937 |
3.32e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 44.46 E-value: 3.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 768 QQERERARQRFQQHLEQEQWALQQQRQRLYSEVaeerERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQ 847
Cdd:COG2433 390 LPEEEPEAEREKEHEERELTEEEEEIRRLEEQV----ERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRKDR 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 848 E-RRHQMELNTLKQQLELERQAWEAGRTRKERMspQEAWLLNREQELR--EEIRKGRDKEIElvihRLEADMALAK---- 920
Cdd:COG2433 466 EiSRLDREIERLERELEEERERIEELKRKLERL--KELWKLEHSGELVpvKVVEKFTKEAIR----RLEEEYGLKEgdvv 539
|
170
....*....|....*....
gi 767994123 921 --EESEKAAESRIKRLRDK 937
Cdd:COG2433 540 ylRDASGAGRSTAELLAEA 558
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
579-1027 |
4.80e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.44 E-value: 4.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 579 EVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQ---LQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAEL 655
Cdd:pfam12128 277 RQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAAdaaVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSEL 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 656 KQEDQRC---TERVAQAQAQHELEIKKLKElmsatEKARREKWISEKTKKIKEVTVRG--------------LEPEIQKL 718
Cdd:pfam12128 357 ENLEERLkalTGKHQDVTAKYNRRRSKIKE-----QNNRDIAGIKDKLAKIREARDRQlavaeddlqaleseLREQLEAG 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 719 IARHKQEVRRLKS-LHEAELLQSDERASQRCLRQAEELREQLEREKEALG---------QQERERARQRFQQ-------- 780
Cdd:pfam12128 432 KLEFNEEEYRLKSrLGELKLRLNQATATPELLLQLENFDERIERAREEQEaanaeverlQSELRQARKRRDQasealrqa 511
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 781 --HLEQEQWALQQQRQRLY-----------SEVAEERERLGQQAARQ---RAELE------------------------- 819
Cdd:pfam12128 512 srRLEERQSALDELELQLFpqagtllhflrKEAPDWEQSIGKVISPEllhRTDLDpevwdgsvggelnlygvkldlkrid 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 820 -----ELRQQLEESSSALTRALRAEFEKGREEQERRHQM--ELNTLKQQLELERQAWEAGRTRKERMSPQEAWL------ 886
Cdd:pfam12128 592 vpewaASEEELRERLDKAEEALQSAREKQAAAEEQLVQAngELEKASREETFARTALKNARLDLRRLFDEKQSEkdkknk 671
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 887 -LNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGE 965
Cdd:pfam12128 672 aLAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKA 751
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 966 AEGENLR------------------LQGLVRQKERALEDAQAV-------NEQLSSERSNLAQVIRQ------EFEDRLA 1014
Cdd:pfam12128 752 LETWYKRdlaslgvdpdviaklkreIRTLERKIERIAVRRQEVlryfdwyQETWLQRRPRLATQLSNieraisELQQQLA 831
|
570
....*....|...
gi 767994123 1015 ASEEETRQAKAEL 1027
Cdd:pfam12128 832 RLIADTKLRRAKL 844
|
|
| MARTX_Nterm |
NF012221 |
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ... |
780-1022 |
5.45e-04 |
|
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.
Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 44.44 E-value: 5.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 780 QHLEQEQWAlqqQRQRLYSEVAEE-RERLGQQAARQRAELEELRQQLEESS-SALTRALRAEFEKGREEQeRRHQMELNT 857
Cdd:NF012221 1549 KHAKQDDAA---QNALADKERAEAdRQRLEQEKQQQLAAISGSQSQLESTDqNALETNGQAQRDAILEES-RAVTKELTT 1624
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 858 LKQQLE-LERQAWEAGRTRKERMSPQEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKaaesrikrlrd 936
Cdd:NF012221 1625 LAQGLDaLDSQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAK----------- 1693
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 937 kyeaelSE--LEQSERKLQErcSELKGQLGEAEGENLRLQGLVRQKE---------RALEDAQAVNEQLSSERSNLAQVI 1005
Cdd:NF012221 1694 ------SEagVAQGEQNQAN--AEQDIDDAKADAEKRKDDALAKQNEaqqaesdanAAANDAQSRGEQDASAAENKANQA 1765
|
250
....*....|....*...
gi 767994123 1006 RQEFED-RLAASEEETRQ 1022
Cdd:NF012221 1766 QADAKGaKQDESDKPNRQ 1783
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
788-930 |
6.70e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 43.59 E-value: 6.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 788 ALQQQRQRLYSEVAEERERLGQQAARQRAEL----EELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTlkqqlE 863
Cdd:pfam09731 295 EIDQLSKKLAELKKREEKHIERALEKQKEELdklaEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRT-----E 369
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767994123 864 LERQAWEAGRTRKERMSPQEAwLLNRE--QELREEIRKGRDKEIELVihrleADMALAKEESEKAAESR 930
Cdd:pfam09731 370 LERQAEAHEEHLKDVLVEQEI-ELQREflQDIKEKVEEERAGRLLKL-----NELLANLKGLEKATSSH 432
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
575-1040 |
8.20e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 8.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 575 RLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQRehyeatiqrhlafidqliedkkvlsEKCEAVVAE 654
Cdd:COG4913 266 AARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAEL-------------------------ERLEARLDA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 655 LKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKW--ISEKTKKIkEVTVRGLEPEIQKLIARHKQEVRRLKSL 732
Cdd:COG4913 321 LREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRarLEALLAAL-GLPLPASAEEFAALRAEAAALLEALEEE 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 733 HEAelLQSDERASQRCLRQAEELREQLEREKEALGQ------QERERARQRFQQHL------------------EQEQW- 787
Cdd:COG4913 400 LEA--LEEALAEAEAALRDLRRELRELEAEIASLERrksnipARLLALRDALAEALgldeaelpfvgelievrpEEERWr 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 788 -----ALQQQRQRL------YSEVAE--ERERLGQ------------QAARQRAELEELRQQLEESSSALTRALRAEFEK 842
Cdd:COG4913 478 gaierVLGGFALTLlvppehYAAALRwvNRLHLRGrlvyervrtglpDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGR 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 843 GR-------EEQERRHQMELnTLKQQLELERQAWEAGRTRKERmspqEAWLL---NREQ--ELREEIRkgrdkEIELVIH 910
Cdd:COG4913 558 RFdyvcvdsPEELRRHPRAI-TRAGQVKGNGTRHEKDDRRRIR----SRYVLgfdNRAKlaALEAELA-----ELEEELA 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 911 RLEADMALAKEESEkaaesRIKRLRDKYE--AELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQ 988
Cdd:COG4913 628 EAEERLEALEAELD-----ALQERREALQrlAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELE 702
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 767994123 989 AVNEQLssersNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEE 1040
Cdd:COG4913 703 ELEEEL-----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
809-1033 |
1.14e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 43.24 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 809 QQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRhqMELNTLKQQLELERQAWEAgrtrkeRMSPQEawllN 888
Cdd:pfam01576 22 QKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMR--ARLAARKQELEEILHELES------RLEEEE----E 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 889 REQELREEIRKGRDKEIELVIHRLEADMALAKEESEK-AAESRIKRLRDK---YEAELSELEQSERKLQERCSELKGQLG 964
Cdd:pfam01576 90 RSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKvTTEAKIKKLEEDillLEDQNSKLSKERKLLEERISEFTSNLA 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767994123 965 EAEGENLRLQGLVRQKERALEDAQavneqlssERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQAR 1033
Cdd:pfam01576 170 EEEEKAKSLSKLKNKHEAMISDLE--------ERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQ 230
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
567-840 |
1.36e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 567 SEVSTSVMRLKLEVEEKKQAMLLLQRA---LAQQRDLTARRVKETEKALSRQLQrQREHYEATIQRHLAFIDQLIEDKKV 643
Cdd:TIGR02168 729 SALRKDLARLEAEVEQLEERIAQLSKElteLEAEIEELEERLEEAEEELAEAEA-EIEELEAQIEQLKEELKALREALDE 807
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 644 LsekcEAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREkwISEKTKKIKEVTVRGLEPEIQ---KLIA 720
Cdd:TIGR02168 808 L----RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED--IESLAAEIEELEELIEELESEleaLLNE 881
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 721 RHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALgQQERERARQRFQQHLEQ--EQWAL--------- 789
Cdd:TIGR02168 882 RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL-ELRLEGLEVRIDNLQERlsEEYSLtleeaeale 960
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767994123 790 -------QQQRQRL--------------------YSEVAEERERLgqqaARQRAELEELRQQLEESSSALTRALRAEF 840
Cdd:TIGR02168 961 nkieddeEEARRRLkrlenkikelgpvnlaaieeYEELKERYDFL----TAQKEDLTEAKETLEEAIEEIDREARERF 1034
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
635-1001 |
1.49e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 42.85 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 635 DQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAqAQAQHELEIKKLKELMSATEKARRE--KWISEKTKKIKEVtVRGLE 712
Cdd:pfam01576 738 EQGEEKRRQLVKQVRELEAELEDERKQRAQAVA-AKKKLELDLKELEAQIDAANKGREEavKQLKKLQAQMKDL-QRELE 815
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 713 PEIQ---KLIARHKQEVRRLKSLhEAELLQSDER--ASQRCLRQAeelreqlerekealgQQERERARQRFQQHLEQEqw 787
Cdd:pfam01576 816 EARAsrdEILAQSKESEKKLKNL-EAELLQLQEDlaASERARRQA---------------QQERDELADEIASGASGK-- 877
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 788 alqqqrqrlySEVAEERERLGQQAARQRAELEELRQQLEESSsaltralraefekgreEQERRHQMELNTLKQQLELERQ 867
Cdd:pfam01576 878 ----------SALQDEKRRLEARIAQLEEELEEEQSNTELLN----------------DRLRKSTLQVEQLTTELAAERS 931
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 868 AWEAGRTRKERMSPQEAWLLNREQELREEIRKgrdkEIELVIHRLEADMA-----LAKEESEKAAESRIKRLRDKYEAEL 942
Cdd:pfam01576 932 TSQKSESARQQLERQNKELKAKLQEMEGTVKS----KFKSSIAALEAKIAqleeqLEQESRERQAANKLVRRTEKKLKEV 1007
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 943 SELEQSER-----------KLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNL 1001
Cdd:pfam01576 1008 LLQVEDERrhadqykdqaeKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTL 1077
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
795-1034 |
2.05e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.80 E-value: 2.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 795 RLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREeqerrhqmelntLKQQLELERQAWEAGRT 874
Cdd:pfam07888 48 QAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEE------------LEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 875 RKERMSPQEAWLLNREQELREEIR----KGRDKEIELVIHRLEADMALAKEESEKAAesrikrlRDKYEAELSELEQSER 950
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEDIKtltqRVLERETELERMKERAKKAGAQRKEEEAE-------RKQLQAKLQQTEEELR 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 951 KLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQ---AVNEQLSSERSNLaqvirqefEDRLAASEEETRQAKAEL 1027
Cdd:pfam07888 189 SLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHrkeAENEALLEELRSL--------QERLNASERKVEGLGEEL 260
|
....*..
gi 767994123 1028 ATLQARQ 1034
Cdd:pfam07888 261 SSMAAQR 267
|
|
| GBP_C |
cd16269 |
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
799-907 |
2.98e-03 |
|
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.
Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 41.02 E-value: 2.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 799 EVAEERERlGQQAARQRAELEELRQQLEESssaltralraefekgREEQERRHQMELNTLKQQLELERQaweagRTRKEr 878
Cdd:cd16269 199 EIEAERAK-AEAAEQERKLLEEQQRELEQK---------------LEDQERSYEEHLRQLKEKMEEERE-----NLLKE- 256
|
90 100
....*....|....*....|....*....
gi 767994123 879 mspQEAWLLNREQELREEIRKGRDKEIEL 907
Cdd:cd16269 257 ---QERALESKLKEQEALLEEGFKEQAEL 282
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
768-947 |
3.10e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.87 E-value: 3.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 768 QQERERARQRFQQHLEQeQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELRQQLEesssaltralraefekgreeq 847
Cdd:PRK04863 532 QQRAERLLAEFCKRLGK-NLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLE--------------------- 589
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 848 errhqmELNTLKQQLELERQAWEAGRTRKERMSPQEAWLLNREQELREEIRKGRDKEIELVIHRLEAdmalakEESEKAA 927
Cdd:PRK04863 590 ------QLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDEL------AARKQAL 657
|
170 180
....*....|....*....|
gi 767994123 928 ESRIKRLRDKYEAELSELEQ 947
Cdd:PRK04863 658 DEEIERLSQPGGSEDPRLNA 677
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
886-1040 |
3.74e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.29 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 886 LLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESR-IKRLRDKYEAELSELEQSERKLQERCSELKGQLG 964
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAeLQEELEELEEELEELEAELEELREELEKLEKLLQ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 965 -------------EAEGENLRLQGLvRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQ 1031
Cdd:COG4717 127 llplyqelealeaELAELPERLEEL-EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQ 205
|
....*....
gi 767994123 1032 ARQQLELEE 1040
Cdd:COG4717 206 QRLAELEEE 214
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
533-1047 |
4.01e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.25 E-value: 4.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 533 MSFLDEMEKSGQDQLDSQ---QEGWVPEAGPGPLELGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDLTARrvKETE 609
Cdd:pfam05483 259 LTFLLEESRDKANQLEEKtklQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEE--KEAQ 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 610 KALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCT---ERVAQAQAQHELEIKKLKELMSA 686
Cdd:pfam05483 337 MEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSselEEMTKFKNNKEVELEELKKILAE 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 687 TEKARREKwisEKTKKIKEvTVRGLEPEIQKLIARHKQEVrrlkslHEAEL-LQSDERASQRCLRQAEELREQleREKEA 765
Cdd:pfam05483 417 DEKLLDEK---KQFEKIAE-ELKGKEQELIFLLQAREKEI------HDLEIqLTAIKTSEEHYLKEVEDLKTE--LEKEK 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 766 LGQQERERARQRfqqhLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRAELEELrQQLEESSSALTRAL---RAEFEK 842
Cdd:pfam05483 485 LKNIELTAHCDK----LLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQI-ENLEEKEMNLRDELesvREEFIQ 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 843 GREE--------QERRHQMELNTLKQQLELERQAWEAGRTRKErMSPQEAWLLNREQELREEIRKG--RDKEI---ELVI 909
Cdd:pfam05483 560 KGDEvkckldksEENARSIEYEVLKKEKQMKILENKCNNLKKQ-IENKNKNIEELHQENKALKKKGsaENKQLnayEIKV 638
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 910 HRLEADMALAKEESEKaaesrikrLRDKYEAELSELEQSERKLQERCSELKGQLGEA----EGENLRLQGLVRQKERALE 985
Cdd:pfam05483 639 NKLELELASAKQKFEE--------IIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAvklqKEIDKRCQHKIAEMVALME 710
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767994123 986 DAQAVNEQLSSERSN---LAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEEGEDSPRE 1047
Cdd:pfam05483 711 KHKHQYDKIIEERDSelgLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKME 775
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
819-1040 |
4.47e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.11 E-value: 4.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 819 EELRQQLEESS--SALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKERMspqeawLLNREQELREE 896
Cdd:pfam02463 152 PERRLEIEEEAagSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQ------LKEKLELEEEY 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 897 IRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGL 976
Cdd:pfam02463 226 LLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKL 305
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767994123 977 VRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEE 1040
Cdd:pfam02463 306 ERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLE 369
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
818-1033 |
4.62e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.65 E-value: 4.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 818 LEELRQQLEESSSALTRALRAEFEKGREEQERRHQMEL----NTLKQQLELERQAWEAGRTRKERmspQEAWLLNREQEL 893
Cdd:pfam07888 9 LEEESHGEEGGTDMLLVVPRAELLQNRLEECLQERAELlqaqEAANRQREKEKERYKRDREQWER---QRRELESRVAEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 894 REEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIkrlRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRL 973
Cdd:pfam07888 86 KEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQ---RAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKA 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 974 QGLVRQKERALEDAQAVNEQLSSERSNLAQVIrQEFEDRLAASEEETRQAKAELATLQAR 1033
Cdd:pfam07888 163 GAQRKEEEAERKQLQAKLQQTEEELRSLSKEF-QELRNSLAQRDTQVLQLQDTITTLTQK 221
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
593-1032 |
4.69e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.10 E-value: 4.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 593 ALAQQRDLTARRVkETEKALSRQLQRQREHYEATIQRHLAFidqliedkkVLSEKCEAVVAELKQEDQRCTERVAQAQA- 671
Cdd:PRK04863 790 QLRAEREELAERY-ATLSFDVQKLQRLHQAFSRFIGSHLAV---------AFEADPEAELRQLNRRRVELERALADHESq 859
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 672 --QHELEIKKLKELMSATEKARREKWISEKTKKIKEVtvRGLEPEIQKL------IARHKQEVRRLKSLheAELLQSDer 743
Cdd:PRK04863 860 eqQQRSQLEQAKEGLSALNRLLPRLNLLADETLADRV--EEIREQLDEAeeakrfVQQHGNALAQLEPI--VSVLQSD-- 933
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 744 asqrclrqaeelreqlerekealgQQERERARQRFQQhlEQEQWALQQQRQRLYSEVAEERERLGQQAARQR----AEL- 818
Cdd:PRK04863 934 ------------------------PEQFEQLKQDYQQ--AQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMlaknSDLn 987
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 819 EELRQQLEESSSALTRAlraefekgrEEQERRHQMELNTLKQQLelerQAWEAGRTRKERMSpqeawllnreQELREEIr 898
Cdd:PRK04863 988 EKLRQRLEQAEQERTRA---------REQLRQAQAQLAQYNQVL----ASLKSSYDAKRQML----------QELKQEL- 1043
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 899 kgrdkeielvihrleADMAL-AKEESEKAAESRikrlRDKYEAELSEleqserkLQERCSELKGQLGEAEGEnlrLQGLV 977
Cdd:PRK04863 1044 ---------------QDLGVpADSGAEERARAR----RDELHARLSA-------NRSRRNQLEKQLTFCEAE---MDNLT 1094
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 767994123 978 RQKERALEDAQAVNEQLSSERSNLAQVIRqefedRLAASEEETRQAKAELATLQA 1032
Cdd:PRK04863 1095 KKLRKLERDYHEMREQVVNAKAGWCAVLR-----LVKDNGVERRLHRRELAYLSA 1144
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
611-705 |
4.79e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 40.97 E-value: 4.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 611 ALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQrctERVAQAQAQHELEIKKLKELMSATEKA 690
Cdd:PRK00409 527 ELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQ---QAIKEAKKEADEIIKELRQLQKGGYAS 603
|
90
....*....|....*
gi 767994123 691 RREKWISEKTKKIKE 705
Cdd:PRK00409 604 VKAHELIEARKRLNK 618
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
903-1022 |
4.86e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 4.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 903 KEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAEL----SELEQSERKLQERCSELKGQLGEAEGENLRLQglvr 978
Cdd:PRK12704 38 EEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELrerrNELQKLEKRLLQKEENLDRKLELLEKREEELE---- 113
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 767994123 979 QKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQ 1022
Cdd:PRK12704 114 KKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAKE 157
|
|
| CHASE3 |
COG5278 |
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms]; |
714-1054 |
6.01e-03 |
|
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 40.66 E-value: 6.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 714 EIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQR 793
Cdd:COG5278 94 ELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLLALALAALLLAAA 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 794 QRL-----YSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQA 868
Cdd:COG5278 174 ALLllllaLAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLAL 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 869 WEAGRTRKERMSPQEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQS 948
Cdd:COG5278 254 LAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALAL 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 949 ERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELA 1028
Cdd:COG5278 334 ATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAA 413
|
330 340
....*....|....*....|....*.
gi 767994123 1029 TLQARQQLELEEGEDSPREEGGGREQ 1054
Cdd:COG5278 414 AAASAAEALELAEALAEALALAEEEA 439
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
573-1037 |
7.29e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.42 E-value: 7.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 573 VMRLKLEVEEKKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQR-QREHYEATIQRHLAFIDQLIEDKKVLSEKCEAV 651
Cdd:TIGR00606 441 TIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERElSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKL 520
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 652 VAELKQEDQRCTER-----VAQAQAQHELEIKKLK-----ELMSAT----EKARREKWISEKTKKIK--EVTVRGLEPEI 715
Cdd:TIGR00606 521 DQEMEQLNHHTTTRtqmemLTKDKMDKDEQIRKIKsrhsdELTSLLgyfpNKKQLEDWLHSKSKEINqtRDRLAKLNKEL 600
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 716 QKLIARHKQEVRRLKSLHEAELLQSDErasqrclrqaeelreqlerEKEALGQQERERARQRFQQHLEQ--EQWALQQQR 793
Cdd:TIGR00606 601 ASLEQNKNHINNELESKEEQLSSYEDK-------------------LFDVCGSQDEESDLERLKEEIEKssKQRAMLAGA 661
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 794 QRLYSEVAEERER-------LGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELER 866
Cdd:TIGR00606 662 TAVYSQFITQLTDenqsccpVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDL 741
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 867 QAWEAGRTRKERMSpqeawlLNRE-QELREEIRKgRDKEIELVihrleadmaLAKEESEKAAESRIKRLRDKYEaelsEL 945
Cdd:TIGR00606 742 KEKEIPELRNKLQK------VNRDiQRLKNDIEE-QETLLGTI---------MPEEESAKVCLTDVTIMERFQM----EL 801
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 946 EQSERKLQERCSELKGQLGEAEgenlrlqglVRQKERALEDAQAVNEQLSSERSNLAQVI--RQEFEDRLAASEEETRQA 1023
Cdd:TIGR00606 802 KDVERKIAQQAAKLQGSDLDRT---------VQQVNQEKQEKQHELDTVVSKIELNRKLIqdQQEQIQHLKSKTNELKSE 872
|
490
....*....|....*
gi 767994123 1024 KAELAT-LQARQQLE 1037
Cdd:TIGR00606 873 KLQIGTnLQRRQQFE 887
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
652-868 |
7.49e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.28 E-value: 7.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 652 VAELKQEDQRCTERVAQAQAQheleIKKLKELMSATEKaRREKWISEKTKKIKEVTVRGLEPEIQKLiarhKQEVRRLks 731
Cdd:COG4913 612 LAALEAELAELEEELAEAEER----LEALEAELDALQE-RREALQRLAEYSWDEIDVASAEREIAEL----EAELERL-- 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 732 lheaellqsdeRASQRCLRQAEELReqlEREKEALGQQERERARqrfqqhLEQEQWALQQQRQRLYSEVAEERERLGQ-- 809
Cdd:COG4913 681 -----------DASSDDLAALEEQL---EELEAELEELEEELDE------LKGEIGRLEKELEQAEEELDELQDRLEAae 740
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767994123 810 --QAARQRAELEELRQQLEEssSALTRALRAEFEKGREEQERRhqmeLNTLKQQLELERQA 868
Cdd:COG4913 741 dlARLELRALLEERFAAALG--DAVERELRENLEERIDALRAR----LNRAEEELERAMRA 795
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
712-867 |
7.79e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 38.73 E-value: 7.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 712 EPEIQKLIARHKQEVRRLKSLheaellqsderasqrcLRQAeelreqlerekealgqQERERARQRFQQHLEQEQWALQQ 791
Cdd:pfam15619 55 ESELPQLIARHNEEVRVLRER----------------LRRL----------------QEKERDLERKLKEKEAELLRLRD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 792 QRQRLYSEVAE----ERERLGQQAARQRAELEE-------LRQQLEESSSALTRALRAEFEKGREEQE--RRHQMELNTL 858
Cdd:pfam15619 103 QLKRLEKLSEDknlaEREELQKKLEQLEAKLEDkdekiqdLERKLELENKSFRRQLAAEKKKHKEAQEevKILQEEIERL 182
|
170
....*....|
gi 767994123 859 KQQL-ELERQ 867
Cdd:pfam15619 183 QQKLkEKERE 192
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
779-1023 |
8.20e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.28 E-value: 8.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 779 QQHLEQEQWALQQqrqrlyseVAEERERLGQQAARQRAELEELRQQLEEsSSALTRALRAEFEK-----GREEQERRHQM 853
Cdd:PRK11281 51 QKLLEAEDKLVQQ--------DLEQTLALLDKIDRQKEETEQLKQQLAQ-APAKLRQAQAELEAlkddnDEETRETLSTL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 854 ELNTLKQQLE---LERQAWEAG-----------RTRKERMSPQEAWLLNREQELREEIRKGRDKEIELVIHRleadmala 919
Cdd:PRK11281 122 SLRQLESRLAqtlDQLQNAQNDlaeynsqlvslQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQ-------- 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 920 keesekaaesrikrlRDKYEAELSELEQserKLQERCSELKGqlgeaegeNLRLQGLVrQKERALEDAQAvnEQLSSERS 999
Cdd:PRK11281 194 ---------------RVLLQAEQALLNA---QNDLQRKSLEG--------NTQLQDLL-QKQRDYLTARI--QRLEHQLQ 244
|
250 260
....*....|....*....|....
gi 767994123 1000 NLAQVIRQEfedRLAASEEETRQA 1023
Cdd:PRK11281 245 LLQEAINSK---RLTLSEKTVQEA 265
|
|
| PHA03252 |
PHA03252 |
DNA packaging tegument protein UL25; Provisional |
906-1017 |
8.64e-03 |
|
DNA packaging tegument protein UL25; Provisional
Pssm-ID: 223024 Cd Length: 589 Bit Score: 40.08 E-value: 8.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 906 ELVIHRLEADMALA-KEESEKAAESRIKRLRDKyeaelSELEQSERKLQERCSELKGQLGEAegENLRLQGLVRQKERAL 984
Cdd:PHA03252 28 EEDLRRLRDDSALRlRRYREDLLRDRLLRRRLG-----EELDDLQKRLQTECEDLRSRVSEA--EALLLHDASGGEGGGA 100
|
90 100 110
....*....|....*....|....*....|...
gi 767994123 985 EDAQAVNEQLSSERSNLAQVIRQEFEDRLAASE 1017
Cdd:PHA03252 101 TNGGEVNVDGGADRTWLAQSPERPADGGPSGER 133
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
893-1033 |
8.64e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 39.56 E-value: 8.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767994123 893 LREEIrKGRDKEIELVIHRLeADMA--LAKEESEKAA-ESRIKRLRdkyeAELSELEqSERklqercSELKGQLGEAEGE 969
Cdd:PRK09039 44 LSREI-SGKDSALDRLNSQI-AELAdlLSLERQGNQDlQDSVANLR----ASLSAAE-AER------SRLQALLAELAGA 110
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767994123 970 NLRLQGLVRQKERALEDAQAV-----------NEQLSSERSNLAQVirqefEDRLAASEEETRQAKAELATLQAR 1033
Cdd:PRK09039 111 GAAAEGRAGELAQELDSEKQVsaralaqvellNQQIAALRRQLAAL-----EAALDASEKRDRESQAKIADLGRR 180
|
|
| |
