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Conserved domains on  [gi|768015934|ref|XP_011526855|]
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WAP four-disulfide core domain protein 3 isoform X1 [Homo sapiens]

Protein Classification

WAP domain-containing protein( domain architecture ID 10442762)

WAP domain-containing protein similar to whey acidic protein (WAP) that could be a protease inhibitor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 81-119 5.94e-04

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


:

Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 36.63  E-value: 5.94e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 768015934   81 DCPRVIRKQSCLKRCITDETCPGVKKCCTLGCNKSCVVP 119
Cdd:pfam00095   4 CCPRLGARGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 35-73 1.28e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


:

Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.48  E-value: 1.28e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 768015934   35 KEGECPPHKNP--CKELCQGDELCPAEQKCCTTGCGRICRD 73
Cdd:pfam00095   1 KPGCCPRLGARgcCRSCCSSDDDCPGRQKCCSNGCGSVCVP 41
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 174-212 1.48e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


:

Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.48  E-value: 1.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 768015934  174 GDCPKVLV-GLCIVGCVMDENCQAGEKCCKSGCGRFCVPP 212
Cdd:pfam00095   3 GCCPRLGArGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 130-165 4.42e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


:

Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 34.32  E-value: 4.42e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 768015934  130 GECPA--DPLPCEELCDGDASCPQGHKCCSTGCGRTCL 165
Cdd:pfam00095   3 GCCPRlgARGCCRSCCSSDDDCPGRQKCCSNGCGSVCV 40
 
Name Accession Description Interval E-value
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 81-119 5.94e-04

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 36.63  E-value: 5.94e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 768015934   81 DCPRVIRKQSCLKRCITDETCPGVKKCCTLGCNKSCVVP 119
Cdd:pfam00095   4 CCPRLGARGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 35-73 1.28e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.48  E-value: 1.28e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 768015934   35 KEGECPPHKNP--CKELCQGDELCPAEQKCCTTGCGRICRD 73
Cdd:pfam00095   1 KPGCCPRLGARgcCRSCCSSDDDCPGRQKCCSNGCGSVCVP 41
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 174-212 1.48e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.48  E-value: 1.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 768015934  174 GDCPKVLV-GLCIVGCVMDENCQAGEKCCKSGCGRFCVPP 212
Cdd:pfam00095   3 GCCPRLGArGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 130-165 4.42e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 34.32  E-value: 4.42e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 768015934  130 GECPA--DPLPCEELCDGDASCPQGHKCCSTGCGRTCL 165
Cdd:pfam00095   3 GCCPRlgARGCCRSCCSSDDDCPGRQKCCSNGCGSVCV 40
 
Name Accession Description Interval E-value
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 81-119 5.94e-04

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 36.63  E-value: 5.94e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 768015934   81 DCPRVIRKQSCLKRCITDETCPGVKKCCTLGCNKSCVVP 119
Cdd:pfam00095   4 CCPRLGARGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 35-73 1.28e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.48  E-value: 1.28e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 768015934   35 KEGECPPHKNP--CKELCQGDELCPAEQKCCTTGCGRICRD 73
Cdd:pfam00095   1 KPGCCPRLGARgcCRSCCSSDDDCPGRQKCCSNGCGSVCVP 41
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 174-212 1.48e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 35.48  E-value: 1.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 768015934  174 GDCPKVLV-GLCIVGCVMDENCQAGEKCCKSGCGRFCVPP 212
Cdd:pfam00095   3 GCCPRLGArGCCRSCCSSDDDCPGRQKCCSNGCGSVCVPP 42
WAP pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or ...
 130-165 4.42e-03

WAP-type (Whey Acidic Protein) 'four-disulfide core'; WAP belongs to the group of Elafin or elastase-specific inhibitors.


Pssm-ID: 459672 [Multi-domain]  Cd Length: 42  Bit Score: 34.32  E-value: 4.42e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 768015934  130 GECPA--DPLPCEELCDGDASCPQGHKCCSTGCGRTCL 165
Cdd:pfam00095   3 GCCPRlgARGCCRSCCSSDDDCPGRQKCCSNGCGSVCV 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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