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Conserved domains on  [gi|767932077|ref|XP_011530322|]
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kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X3 [Homo sapiens]

Protein Classification

PLP-dependent aminotransferase family protein( domain architecture ID 11439382)

pyridoxal phosphate (PLP)-dependent aminotransferase family protein may catalyze the reversible exchange of an amino group from one molecule with a keto group from another molecule

CATH:  3.40.640.10
Gene Ontology:  GO:0030170
PubMed:  17109392
SCOP:  4000670

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 9-310 5.35e-82

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


:

Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 255.52  E-value: 5.35e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPedaknpqkntpKFLYTVPNGNNP 88
Cdd:COG1167  186 ALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVDEDGLDLDALEAALRRHRP-----------RAVYVTPSHQNP 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  89 TGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIER 168
Cdd:COG1167  255 TGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAPGRVIYIGSFSKTLAPGLRLGYLVAPGRLIER 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 169 VILHIQVSTLHPSTFNQLMISQLLhewgEEG-FMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKV-K 246
Cdd:COG1167  335 LARLKRATDLGTSPLTQLALAEFL----ESGhYDRHLRRLRREYRARRDLLLAALARHLPDGLRVTGPPGGLHLWLELpE 410

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767932077 247 GINDVKelIEEKAVKMGVLMLPGNAFYVDsSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL 310
Cdd:COG1167  411 GVDAEA--LAAAALARGILVAPGSAFSAD-GPPRNGLRLGFGAPSEEELEEALRRLAELLRELA 471
 
Name Accession Description Interval E-value
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 9-310 5.35e-82

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 255.52  E-value: 5.35e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPedaknpqkntpKFLYTVPNGNNP 88
Cdd:COG1167  186 ALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVDEDGLDLDALEAALRRHRP-----------RAVYVTPSHQNP 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  89 TGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIER 168
Cdd:COG1167  255 TGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAPGRVIYIGSFSKTLAPGLRLGYLVAPGRLIER 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 169 VILHIQVSTLHPSTFNQLMISQLLhewgEEG-FMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKV-K 246
Cdd:COG1167  335 LARLKRATDLGTSPLTQLALAEFL----ESGhYDRHLRRLRREYRARRDLLLAALARHLPDGLRVTGPPGGLHLWLELpE 410

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767932077 247 GINDVKelIEEKAVKMGVLMLPGNAFYVDsSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL 310
Cdd:COG1167  411 GVDAEA--LAAAALARGILVAPGSAFSAD-GPPRNGLRLGFGAPSEEELEEALRRLAELLRELA 471
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 9-304 1.56e-60

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 196.41  E-value: 1.56e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDIlsrwkpEDAKNPQkntPKFLYTVpNGNNP 88
Cdd:cd00609   75 LLRALLNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELL------EAAKTPK---TKLLYLN-NPNNP 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  89 TGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIIS-SGLRIGFLTGPKP-LI 166
Cdd:cd00609  145 TGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALALLDAYERVIVLRSFSKTFGlPGLRIGYLIAPPEeLL 224

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 167 ERVILHIQVSTLHPSTFNQLMISQLLHEWGEegfmaHVDRVIDFYSNQKDAILAAADKWltGLAEWHVPAAGMFLWIKVK 246
Cdd:cd00609  225 ERLKKLLPYTTSGPSTLSQAAAAAALDDGEE-----HLEELRERYRRRRDALLEALKEL--GPLVVVKPSGGFFLWLDLP 297

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767932077 247 GINDvKELIEEKAVKMGVLMLPGNAFYvdsSAPSPYLRASFSSaSPEQMDVAFQVLAQ 304
Cdd:cd00609  298 EGDD-EEFLERLLLEAGVVVRPGSAFG---EGGEGFVRLSFAT-PEEELEEALERLAE 350
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
12-302 5.43e-18

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 83.12  E-value: 5.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   12 MIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVA---SDESGIVPDSLRDILsrwkpedaknpqKNTPKFLYtVPNGNNP 88
Cdd:pfam00155  82 LLANPGDAILVPAPTYASYIRIARLAGGEVVRYPlydSNDFHLDFDALEAAL------------KEKPKVVL-HTSPHNP 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   89 TGNSLTSERKKEIYELARKYDFLIIEDDPY---YFLQFNKFRVPTFLSMDVDGRVIRadSFSKIISS-GLRIGFLTGPKP 164
Cdd:pfam00155 149 TGTVATLEELEKLLDLAKEHNILLLVDEAYagfVFGSPDAVATRALLAEGPNLLVVG--SFSKAFGLaGWRVGYILGNAA 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  165 LIERVIlhIQVSTLHPSTFNQLMISQLLHewgeegfmaHVDRVIDFYSNQKDAILAAADKWLTGLAE----WHVPAAGMF 240
Cdd:pfam00155 227 VISQLR--KLARPFYSSTHLQAAAAAALS---------DPLLVASELEEMRQRIKERRDYLRDGLQAaglsVLPSQAGFF 295

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767932077  241 LWIKVKGINDV---KELIEEKavkmGVLMLPGNAFYVDSSapspyLRASFSSASPEQMDVAFQVL 302
Cdd:pfam00155 296 LLTGLDPETAKelaQVLLEEV----GVYVTPGSSPGVPGW-----LRITVAGGTEEELEELLEAI 351
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
74-307 3.69e-16

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 78.06  E-value: 3.69e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  74 NTPkflytvpngNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKF-RVPTFLS-MDVDGRVIRADSFSKIIS 151
Cdd:PRK06108 165 NSP---------NNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGgRAPSFLDiAEPDDRIIFVNSFSKNWA 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 152 -SGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQlmisqllhewgeEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLA 230
Cdd:PRK06108 236 mTGWRLGWLVAPPALGQVLEKLIEYNTSCVAQFVQ------------RAAVAALDEGEDFVAELVARLRRSRDHLVDALR 303

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 231 -----EWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFyvdssAP--SPYLRASFSSaSPEQMDVAFQVLA 303
Cdd:PRK06108 304 alpgvEVAKPDGAMYAFFRIPGVTDSLALAKRLVDEAGLGLAPGTAF-----GPggEGFLRWCFAR-DPARLDEAVERLR 377


                 ....
gi 767932077 304 QLIK 307
Cdd:PRK06108 378 RFLA 381
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
 7-295 8.56e-10

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 59.28  E-value: 8.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077    7 EKVFEMIINPGDNVLLDEPAYS--GTLQSLHPLGCNIINVASDES-GIVPDSLRDILSrwkpedaknpqKNTPKFLytVP 83
Cdd:TIGR01265 110 EICIEALANPGANILVPRPGFPlyDTRAAFSGLEVRLYDLLPEKDwEIDLDGLESLAD-----------EKTVAIV--VI 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   84 NGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfrvPTFLSMDVDGR---VIRADSFSK-IISSGLRIGFL 159
Cdd:TIGR01265 177 NPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGD---APFIPMASFASivpVLSLGGISKrWVVPGWRLGWI 253

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  160 T--GPKPLIERVILH--IQVS--TLHPSTFNQLMISQLLHEWGEEGFmahvDRVIDFYSNQKDaILAAADKWLTGLAEWH 233
Cdd:TIGR01265 254 IihDPHGIFRDTVLQglKNLLqrILGPATIVQGALPDILENTPQEFF----DGKISVLKSNAE-LCYEELKDIPGLVCPK 328

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767932077  234 vPAAGMFLWIKV-----KGINDVKELIEEKAVKMGVLMLPGNAFyvdsSAPSpYLRASFssASPEQM 295
Cdd:TIGR01265 329 -PEGAMYLMVKLelelfPEIKDDVDFCEKLAREESVICLPGSAF----GLPN-WVRITI--TVPESM 387
 
Name Accession Description Interval E-value
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 9-310 5.35e-82

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 255.52  E-value: 5.35e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPedaknpqkntpKFLYTVPNGNNP 88
Cdd:COG1167  186 ALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVDEDGLDLDALEAALRRHRP-----------RAVYVTPSHQNP 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  89 TGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIER 168
Cdd:COG1167  255 TGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAPGRVIYIGSFSKTLAPGLRLGYLVAPGRLIER 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 169 VILHIQVSTLHPSTFNQLMISQLLhewgEEG-FMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKV-K 246
Cdd:COG1167  335 LARLKRATDLGTSPLTQLALAEFL----ESGhYDRHLRRLRREYRARRDLLLAALARHLPDGLRVTGPPGGLHLWLELpE 410

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767932077 247 GINDVKelIEEKAVKMGVLMLPGNAFYVDsSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL 310
Cdd:COG1167  411 GVDAEA--LAAAALARGILVAPGSAFSAD-GPPRNGLRLGFGAPSEEELEEALRRLAELLRELA 471
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 9-304 1.56e-60

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 196.41  E-value: 1.56e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDIlsrwkpEDAKNPQkntPKFLYTVpNGNNP 88
Cdd:cd00609   75 LLRALLNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELL------EAAKTPK---TKLLYLN-NPNNP 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  89 TGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIIS-SGLRIGFLTGPKP-LI 166
Cdd:cd00609  145 TGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALALLDAYERVIVLRSFSKTFGlPGLRIGYLIAPPEeLL 224

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 167 ERVILHIQVSTLHPSTFNQLMISQLLHEWGEegfmaHVDRVIDFYSNQKDAILAAADKWltGLAEWHVPAAGMFLWIKVK 246
Cdd:cd00609  225 ERLKKLLPYTTSGPSTLSQAAAAAALDDGEE-----HLEELRERYRRRRDALLEALKEL--GPLVVVKPSGGFFLWLDLP 297

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767932077 247 GINDvKELIEEKAVKMGVLMLPGNAFYvdsSAPSPYLRASFSSaSPEQMDVAFQVLAQ 304
Cdd:cd00609  298 EGDD-EEFLERLLLEAGVVVRPGSAFG---EGGEGFVRLSFAT-PEEELEEALERLAE 350
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 9-308 6.91e-39

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 141.04  E-value: 6.91e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESgivpdslrdilSRWKPEDAKNPQKNTPK---FLYTVPng 85
Cdd:COG0436  106 ALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEE-----------NGFLPDPEALEAAITPRtkaIVLNSP-- 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  86 NNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSM-DVDGRVIRADSFSKIIS-SGLRIGFLTGPK 163
Cdd:COG0436  173 NNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLpGLKDRTIVINSFSKSYAmTGWRIGYAVGPP 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 164 PLIERVILHIQVSTLHPSTFNQLMISQLLhewgeEGFMAHVDRVIDFYSNQKDAILAAADKwlTGLaEWHVPAAGMFLWI 243
Cdd:COG0436  253 ELIAALLKLQSNLTSCAPTPAQYAAAAAL-----EGPQDYVEEMRAEYRRRRDLLVEGLNE--IGL-SVVKPEGAFYLFA 324

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 244 KVKGIND-----VKELIEEKavkmGVLMLPGNAFYvdsSAPSPYLRASFsSASPEQMDVAFQVLAQLIKE 308
Cdd:COG0436  325 DVPELGLdseefAERLLEEA----GVAVVPGSAFG---PAGEGYVRISY-ATSEERLEEALERLARFLER 386
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
12-302 5.43e-18

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 83.12  E-value: 5.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   12 MIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVA---SDESGIVPDSLRDILsrwkpedaknpqKNTPKFLYtVPNGNNP 88
Cdd:pfam00155  82 LLANPGDAILVPAPTYASYIRIARLAGGEVVRYPlydSNDFHLDFDALEAAL------------KEKPKVVL-HTSPHNP 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   89 TGNSLTSERKKEIYELARKYDFLIIEDDPY---YFLQFNKFRVPTFLSMDVDGRVIRadSFSKIISS-GLRIGFLTGPKP 164
Cdd:pfam00155 149 TGTVATLEELEKLLDLAKEHNILLLVDEAYagfVFGSPDAVATRALLAEGPNLLVVG--SFSKAFGLaGWRVGYILGNAA 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  165 LIERVIlhIQVSTLHPSTFNQLMISQLLHewgeegfmaHVDRVIDFYSNQKDAILAAADKWLTGLAE----WHVPAAGMF 240
Cdd:pfam00155 227 VISQLR--KLARPFYSSTHLQAAAAAALS---------DPLLVASELEEMRQRIKERRDYLRDGLQAaglsVLPSQAGFF 295

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767932077  241 LWIKVKGINDV---KELIEEKavkmGVLMLPGNAFYVDSSapspyLRASFSSASPEQMDVAFQVL 302
Cdd:pfam00155 296 LLTGLDPETAKelaQVLLEEV----GVYVTPGSSPGVPGW-----LRITVAGGTEEELEELLEAI 351
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
74-307 3.69e-16

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 78.06  E-value: 3.69e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  74 NTPkflytvpngNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKF-RVPTFLS-MDVDGRVIRADSFSKIIS 151
Cdd:PRK06108 165 NSP---------NNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGgRAPSFLDiAEPDDRIIFVNSFSKNWA 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 152 -SGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQlmisqllhewgeEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLA 230
Cdd:PRK06108 236 mTGWRLGWLVAPPALGQVLEKLIEYNTSCVAQFVQ------------RAAVAALDEGEDFVAELVARLRRSRDHLVDALR 303

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 231 -----EWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFyvdssAP--SPYLRASFSSaSPEQMDVAFQVLA 303
Cdd:PRK06108 304 alpgvEVAKPDGAMYAFFRIPGVTDSLALAKRLVDEAGLGLAPGTAF-----GPggEGFLRWCFAR-DPARLDEAVERLR 377


                 ....
gi 767932077 304 QLIK 307
Cdd:PRK06108 378 RFLA 381
avtA PRK09440
valine--pyruvate transaminase; Provisional
 86-308 7.25e-16

valine--pyruvate transaminase; Provisional


Pssm-ID: 236517  Cd Length: 416  Bit Score: 77.20  E-value: 7.25e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  86 NNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYF----LQFNKFRvPTFlsmdvDGRVIRADSFSKIISSGLRIGFLTG 161
Cdd:PRK09440 189 TNPTGNVLTDEELEKLDALARQHNIPLLIDNAYGPpfpgIIFSEAT-PLW-----NPNIILCMSLSKLGLPGVRCGIVIA 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 162 PKPLIErVILHIQ-VSTLHPSTFNQLMISQLLhewgEEGFMAHV-DRVI-DFYSNQKDAILAAADKWLTGLaEW--HVPA 236
Cdd:PRK09440 263 DEEIIE-ALSNMNgIISLAPGRLGPAIAAEMI----ESGDLLRLsETVIrPFYRQKVQLAIALLRRYLPDE-PCliHKPE 336

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767932077 237 AGMFLWIKVKG--INDvKELIEE-KAVkmGVLMLPGNAFYVDSSAPSPY----LRASFsSASPEQMDVAFQVLAQLIKE 308
Cdd:PRK09440 337 GAIFLWLWFKDlpITT-EELYQRlKAR--GVLVVPGHYFFPGLDEDWPHahqcIRMNY-VQDDEEIEKGIAILAEEVEK 411
PRK05764 PRK05764
aspartate aminotransferase; Provisional
 9-287 6.98e-15

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 74.39  E-value: 6.98e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESG---IVPDSLRDILsrwkpedaknpqknTPK---FLYTV 82
Cdd:PRK05764 107 AFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPTGEENgfkLTVEQLEAAI--------------TPKtkaLILNS 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  83 PNgnNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSM--DVDGRVIRADSFSKIIS-SGLRIGFL 159
Cdd:PRK05764 173 PS--NPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTSIASLspELRDRTITVNGFSKAYAmTGWRLGYA 250

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 160 TGPKPLIeRVILHIQV-STLHPSTFNQlmisqllheWGE----EGFMAHVDRVIDFYSNQKDAILAAADKwLTGLaewHV 234
Cdd:PRK05764 251 AGPKELI-KAMSKLQShSTSNPTSIAQ---------YAAvaalNGPQDEVEEMRQAFEERRDLMVDGLNE-IPGL---EC 316

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767932077 235 PAA-GMF-LWIKVKGIND---------VKELIEEKavkmGVLMLPGNAFyvdssAPSPYLRASF 287
Cdd:PRK05764 317 PKPeGAFyVFPNVSKLLGksitdslefAEALLEEA----GVAVVPGIAF-----GAPGYVRLSY 371
PRK07777 PRK07777
putative succinyldiaminopimelate transaminase DapC;
16-305 2.09e-14

putative succinyldiaminopimelate transaminase DapC;


Pssm-ID: 236095 [Multi-domain]  Cd Length: 387  Bit Score: 72.76  E-value: 2.09e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  16 PGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESG----IVPDSLRDilsrwkpedAKNPQK-----NTPkflytvpngN 86
Cdd:PRK07777 108 PGDEVLLIEPYYDSYAAVIAMAGAHRVPVPLVPDGrgfaLDLDALRA---------AVTPRTralivNSP---------H 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  87 NPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFR---VPTFLSMdvDGRVIRADSFSKIIS-SGLRIGFLTGP 162
Cdd:PRK07777 170 NPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARhlpLATLPGM--RERTVTISSAAKTFNvTGWKIGWACGP 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 163 KPLIERVILHIQVSTLHPSTFNQLMISQLLhewgeegfmAHVDrviDFYSNQKDAILAAADKWLTGLAEW----HVPAAG 238
Cdd:PRK07777 248 APLIAAVRAAKQYLTYVGGAPFQPAVAHAL---------DHED---AWVAALRDSLQAKRDRLAAGLAEAgfevHDSAGT 315

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767932077 239 MFLWIKVKGIND------VKELIEekavKMGVLMLPGNAFYVDSSAPSPYLRASFSSaSPEQMDVAFQVLAQL 305
Cdd:PRK07777 316 YFLCADPRPLGYddgtefCRALPE----RVGVAAIPMSVFYDPADAWNHLVRFAFCK-RDDTLDEAIRRLRAL 383
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
13-221 1.27e-13

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 70.65  E-value: 1.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYS---GTLQSLhplGCNIINVASD-ESGIVPDSLRDILSRWKPedaknpqkNTPKFLYTvpNGNNP 88
Cdd:PRK07568 108 ICDPGDEILVPEPFYAnynGFATSA---GVKIVPVTTKiEEGFHLPSKEEIEKLITP--------KTKAILIS--NPGNP 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  89 TGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSM-DVDGRVIRADSFSKIISS-GLRIGFL-TGPKPL 165
Cdd:PRK07568 175 TGVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLKYTSALSLeGLEDRVIIIDSVSKRYSAcGARIGCLiSKNKEL 254

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767932077 166 IERVILHIQvSTLHPSTFNQLMISQLLhEWGEEGFmahvDRVIDFYSNQKDAILAA 221
Cdd:PRK07568 255 IAAAMKLCQ-ARLSPPTLEQIGAAALL-DTPESYF----DEVREEYKKRRDILYEE 304
PRK08361 PRK08361
aspartate aminotransferase; Provisional
 10-305 6.67e-13

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 68.37  E-value: 6.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  10 FEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESG---IVPDSLRDILSrwkpedaknpqKNTPKFLYTVPNgn 86
Cdd:PRK08361 110 FESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREENefqPDPDELLELIT-----------KRTRMIVINYPN-- 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  87 NPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDgRVIRADSFSKIIS-SGLRIGFLTGPKPL 165
Cdd:PRK08361 177 NPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPMIKYAPD-NTILANSFSKTFAmTGWRLGFVIAPEQV 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 166 IERVI-LHIQVSTlHPSTFNQLMISQLLHEwgEEGFMAhVDRVIDFYSNQKDAILaaadKWLTGLAEWHV--PAAGMFLW 242
Cdd:PRK08361 256 IKDMIkLHAYIIG-NVASFVQIAGIEALRS--KESWKA-VEEMRKEYNERRKLVL----KRLKEMPHIKVfePKGAFYVF 327

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 243 IKVKGIN----DVKELIEEKAvkmGVLMLPGNAFyvdSSAPSPYLRASFSSASP---EQMDVAFQVLAQL 305
Cdd:PRK08361 328 ANIDETGmsseDFAEWLLEKA---RVVVIPGTAF---GKAGEGYIRISYATSKEkliEAMERMEKALEEL 391
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
 14-272 1.48e-12

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 67.24  E-value: 1.48e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  14 INPGDNVLLDEPAY----SGTL------QSLhPLgcniinvaSDESGIVPDsLRDIlsrwkPEDAKNPQK----NTPkfl 79
Cdd:PRK09276 114 VNPGDVVLVPDPGYpvykIGTIfaggepYFM-PL--------KEENGFLPD-LDAI-----PEDVAKKAKlmfiNYP--- 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  80 ytvpngNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLS----MDVdgrVIRADSFSKIIS-SGL 154
Cdd:PRK09276 176 ------NNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDGYKPPSFLEvpgaKDV---GIEFHSLSKTYNmTGW 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 155 RIGFLTGPKPLIE---RVilhiqVSTLHPSTFN--QLM-ISQLlhewgeEGFMAHVDRVIDFYSNQKDAILAAADKwlTG 228
Cdd:PRK09276 247 RIGFAVGNADLIAglgKV-----KSNVDSGVFQaiQEAgIAAL------NGPQEVVEELRKIYQERRDILVEGLRK--LG 313

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 767932077 229 LaEWHVPAAGMFLWIKV-KGIND---VKELIEekavKMGVLMLPGNAF 272
Cdd:PRK09276 314 L-EVEPPKATFYVWAPVpKGYTSaefATLLLD----KAGVVVTPGNGF 356
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
9-272 2.24e-12

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 67.05  E-value: 2.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVAS---DESGIVPDSLRDILSrwkpEDAKNPQKNTPkflytvpng 85
Cdd:PRK06348 105 ALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETyeeDGFQINVKKLEALIT----SKTKAIILNSP--------- 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  86 NNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVP--TFLSMdvDGRVIRADSFSKIIS-SGLRIGFLTGP 162
Cdd:PRK06348 172 NNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFYEDFVPmaTLAGM--PERTITFGSFSKDFAmTGWRIGYVIAP 249

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 163 KPLIERV-ILHIQVSTLHPSTFNQLMISQLLHewgeegFMAHVDRVIDFYsnqKDAILAAAD--KWLTGLAEwHVPAAGM 239
Cdd:PRK06348 250 DYIIETAkIINEGICFSAPTISQRAAIYALKH------RDTIVPLIKEEF---QKRLEYAYKriESIPNLSL-HPPKGSI 319

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 767932077 240 FLWIKVK--GINDV---KELIEEKAvkmgVLMLPGNAF 272
Cdd:PRK06348 320 YAFINIKktGLSSVefcEKLLKEAH----VLVIPGKAF 353
PRK08363 PRK08363
alanine aminotransferase; Validated
 9-183 3.12e-11

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 63.67  E-value: 3.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYsgtlqslhPLGCNIInvasDESGIVPDSLRDI-LSRWKPE--DAKNPQKNTPKFLyTVPNG 85
Cdd:PRK08363 109 IFGALLDPGDEILIPGPSY--------PPYTGLV----KFYGGVPVEYRTIeEEGWQPDidDIRKKITEKTKAI-AVINP 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  86 NNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFN-KFRVPTFLSMDVDgrVIRADSFSKI-ISSGLRIGF--LTG 161
Cdd:PRK08363 176 NNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEgKHVSPGSLTKDVP--VIVMNGLSKVyFATGWRLGYiyFVD 253

                        170       180
                 ....*....|....*....|....*...
gi 767932077 162 PKPLIERV------ILHIQVSTLHPSTF 183
Cdd:PRK08363 254 PEGKLAEVreaidkLARIRLCPNTPAQF 281
PRK06290 PRK06290
LL-diaminopimelate aminotransferase;
14-166 4.30e-11

LL-diaminopimelate aminotransferase;


Pssm-ID: 235772  Cd Length: 410  Bit Score: 63.13  E-value: 4.30e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  14 INPGDNVLLDEPAYSGTLQSLHPLGCNIINVA-SDESGIVPDsLRDIlsrwkPEDAknpqKNTPKFLY-TVPngNNPTGN 91
Cdd:PRK06290 127 INPGDVTLMTVPGYPVTGTHTKYYGGEVYNLPlLEENNFLPD-LDSI-----PKDI----KEKAKLLYlNYP--NNPTGA 194

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767932077  92 SLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfRVPTFLSMDVDGRV-IRADSFSKIIS-SGLRIGFLTGpKPLI 166
Cdd:PRK06290 195 VATKEFYEEVVDFAKENNIIVVQDAAYAALTFDG-KPLSFLSVPGAKEVgVEIHSLSKAYNmTGWRLAFVVG-NELI 269
PRK07324 PRK07324
transaminase; Validated
 9-272 4.95e-11

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 62.65  E-value: 4.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYsgtlQSLHPlgcniinvasdesgiVPDSLRDILSRWKPEDAKN--PQKN------TPKF-L 79
Cdd:PRK07324  96 VLYALVEPGDHVISVYPTY----QQLYD---------------IPESLGAEVDYWQLKEENGwlPDLDelrrlvRPNTkL 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  80 YTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYyfLQFNKfrVPTFLSM-DVDGRVIRADSFSKIIS-SGLRIG 157
Cdd:PRK07324 157 ICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVY--RPLDE--DGSTPSIaDLYEKGISTNSMSKTYSlPGIRVG 232

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 158 FLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLhewgeegfmAHVDRVIDfySNQKdaI----LAAADKWLTG--LAE 231
Cdd:PRK07324 233 WIAANEEVIDILRKYRDYTMICAGVFDDMLASLAL---------EHRDAILE--RNRK--IvrtnLAILDEWVAKepRVS 299

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 767932077 232 WHVPAAGMFLWIKVkginDVKELIEEKAVKM----GVLMLPGNAF 272
Cdd:PRK07324 300 YVKPKAVSTSFVKL----DVDMPSEDFCLKLlketGVLLVPGNRF 340
PRK07682 PRK07682
aminotransferase;
13-298 1.98e-10

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 60.90  E-value: 1.98e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSgtlqSLHPLgcniINVASDESGIVPDSLRDilsRWKPEDAKNPQKNTPK---FLYTVPNgnNPT 89
Cdd:PRK07682 101 IINPGDEVLIVEPSFV----SYAPL----VTLAGGVPVPVATTLEN---EFKVQPAQIEAAITAKtkaILLCSPN--NPT 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  90 GNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfrvpTFLSM-DVDG---RVIRADSFSKIIS-SGLRIGFLTGPKP 164
Cdd:PRK07682 168 GAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDE----AYTSFaSIKGmreRTILISGFSKGFAmTGWRLGFIAAPVY 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 165 LIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEgfmahVDRVIDFYSNQKDAILAAADKwlTGLaEWHVPAAGMFLWIK 244
Cdd:PRK07682 244 FSEAMLKIHQYSMMCAPTMAQFAALEALRAGNDD-----VIRMRDSYRKRRNFFVTSFNE--IGL-TCHVPGGAFYAFPS 315

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767932077 245 VKGINDVKE------LIEEKavkmgVLMLPGNAFyvdssAPS--PYLRASFSSaSPEQMDVA 298
Cdd:PRK07682 316 ISSTGLSSEefaeqlLLEEK-----VAVVPGSVF-----GESgeGFIRCSYAT-SLEQLQEA 366
PRK05942 PRK05942
aspartate aminotransferase; Provisional
 14-304 6.30e-10

aspartate aminotransferase; Provisional


Pssm-ID: 180317  Cd Length: 394  Bit Score: 59.35  E-value: 6.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  14 INPGDNVLLDEPAYSGTLQ-------SLHPLgcniinVASDESGIVPDsLRDIlsrwkPED-AKNPqkntpKFLY-TVPN 84
Cdd:PRK05942 118 VNPGDVVLVPSPAYPAHFRgpliagaQIYPI------ILKPENDWLID-LSSI-----PEEvAQQA-----KILYfNYPS 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  85 gnNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRvPTFLSMDVDGRVIRAD--SFSKIIS-SGLRIGFLTG 161
Cdd:PRK05942 181 --NPTTATAPREFFEEIVAFARKYEIMLVHDLCYAELAFDGYQ-PTSLLEIPGAKDIGVEfhTLSKTYNmAGWRVGFVVG 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 162 PKPLIERviLHIQVSTLHPSTFNQLmisQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAaadkwltGLAE--WHVPA--A 237
Cdd:PRK05942 258 NRHIIQG--LRTLKTNLDYGIFSAL---QKAAETALQLPDSYLQQVQERYRTRRDFLIQ-------GLGElgWNIPPtkA 325

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767932077 238 GMFLWIKVK-GINDVK---ELIEekavKMGVLMLPGNAFyvdSSAPSPYLRASFsSASPEQMDVAFQVLAQ 304
Cdd:PRK05942 326 TMYLWVPCPvGMGSTDfalNVLQ----KTGVVVTPGNAF---GEGGEGYVRISL-IADCDRLGEALDRLKQ 388
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
4-272 7.88e-10

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 59.43  E-value: 7.88e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   4 AHKEKVFemiINPGDNVLLDEPAYSGTLQSLHPLGCNIINVA-SDESGIVPDsLRDIlsrwkPEDAKNPQK----NTPkf 78
Cdd:PRK07681 107 VHLPMVY---ANPGDIILVPDPGYTAYETGIQMAGATSYYMPlKKENDFLPD-LELI-----PEEIADKAKmmilNFP-- 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  79 lytvpngNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRV-IRADSFSKIIS-SGLRI 156
Cdd:PRK07681 176 -------GNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVgVEINSLSKSYSlAGSRI 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 157 GFLTGPKPLIERviLHIQVSTLHPSTFnqLMISQLLHEWGEEGfmahvdrvIDFYSNQKDAILAAADKWLTGLAE--WHV 234
Cdd:PRK07681 249 GYMIGNEEIVRA--LTQFKSNTDYGVF--LPIQKAACAALRNG--------AAFCEKNRGIYQERRDTLVDGFRTfgWNV 316

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 767932077 235 --PAAGMFLWIKV----KGINDVKELIEekavKMGVLMLPGNAF 272
Cdd:PRK07681 317 dkPAGSMFVWAEIpkgwTSLSFAYALMD----RANVVVTPGHAF 356
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
 7-295 8.56e-10

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 59.28  E-value: 8.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077    7 EKVFEMIINPGDNVLLDEPAYS--GTLQSLHPLGCNIINVASDES-GIVPDSLRDILSrwkpedaknpqKNTPKFLytVP 83
Cdd:TIGR01265 110 EICIEALANPGANILVPRPGFPlyDTRAAFSGLEVRLYDLLPEKDwEIDLDGLESLAD-----------EKTVAIV--VI 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   84 NGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfrvPTFLSMDVDGR---VIRADSFSK-IISSGLRIGFL 159
Cdd:TIGR01265 177 NPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGD---APFIPMASFASivpVLSLGGISKrWVVPGWRLGWI 253

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  160 T--GPKPLIERVILH--IQVS--TLHPSTFNQLMISQLLHEWGEEGFmahvDRVIDFYSNQKDaILAAADKWLTGLAEWH 233
Cdd:TIGR01265 254 IihDPHGIFRDTVLQglKNLLqrILGPATIVQGALPDILENTPQEFF----DGKISVLKSNAE-LCYEELKDIPGLVCPK 328

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767932077  234 vPAAGMFLWIKV-----KGINDVKELIEEKAVKMGVLMLPGNAFyvdsSAPSpYLRASFssASPEQM 295
Cdd:TIGR01265 329 -PEGAMYLMVKLelelfPEIKDDVDFCEKLAREESVICLPGSAF----GLPN-WVRITI--TVPESM 387
PRK08068 PRK08068
transaminase; Reviewed
 13-272 1.12e-09

transaminase; Reviewed


Pssm-ID: 181219  Cd Length: 389  Bit Score: 58.78  E-value: 1.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAY----SGTLQS-----LHPLgcniinvaSDESGIVPDslrdiLSRWKPEDAKnpqknTPKFLY-TV 82
Cdd:PRK08068 114 LMNPGDTILVPDPGYpdylSGVALAraqfeTMPL--------IAENNFLPD-----YTKIPEEVAE-----KAKLMYlNY 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  83 PNgnNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRV-IRADSFSKIIS-SGLRIGFLT 160
Cdd:PRK08068 176 PN--NPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFDGQKPVSFLQTPGAKDVgIELYTLSKTFNmAGWRVAFAV 253

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 161 GPKPLIERVIL---HIQVStLHPStFNQLMISQLLhewgeeGFMAHVDRVIDFYSNQKDAILAAADKwltglAEWHV--P 235
Cdd:PRK08068 254 GNESVIEAINLlqdHLFVS-LFGA-IQDAAIEALL------SDQSCVAELVARYESRRNAFISACRE-----IGWEVdaP 320

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 767932077 236 AAGMFLWIKV-KGIN--DVKELIEEKAvkmGVLMLPGNAF 272
Cdd:PRK08068 321 KGSFFAWMPVpKGYTseQFADLLLEKA---HVAVAPGNGF 357
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
13-170 1.48e-09

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 58.20  E-value: 1.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIV--PDSLRDILSRwKPEDAKNPQKNTPkflytvpngNNPTG 90
Cdd:PRK07309 111 ILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENDFVltPEMLEKAILE-QGDKLKAVILNYP---------ANPTG 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  91 NSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDgRVIRADSFSKIIS-SGLRIGFLTGPKPLIERV 169
Cdd:PRK07309 181 VTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHVSIAEYLPD-QTILINGLSKSHAmTGWRIGLIFAPAEFTAQL 259


                 .
gi 767932077 170 I 170
Cdd:PRK07309 260 I 260
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
 16-310 1.62e-09

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 58.52  E-value: 1.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  16 PGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILsrwkpedaknpqKNTPKFLYTVPNGNNPTGNSLTS 95
Cdd:PRK15481 164 PGDSVAVEDPCFLSSINMLRYAGFSASPVSVDAEGMQPEKLERAL------------AQGARAVILTPRAHNPTGCSLSA 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  96 ERKKEIYELARKY-DFLIIEDDPYYFLQfnkfRVPTFLSMDVDGR---VIRadSFSKIISSGLRIGFLTGPKPLIERVIL 171
Cdd:PRK15481 232 RRAAALRNLLARYpQVLVIIDDHFALLS----SSPYHSVIPQTTQrwaLIR--SVSKALGPDLRLAFVASDSATSARLRL 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 172 HIQVSTLHPSTFNQLMISQLLHewgEEGFMAHVDRVIDFYSNQKDAILAAADKwlTGLAEwHVPAAGMFLWIKVKGinDV 251
Cdd:PRK15481 306 RLNSGTQWVSHLLQDLVYACLT---DPEYQARLAQARLFYAQRRQKLARALQQ--YGIAI-PSPGDGLNLWLPLDT--DS 377

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767932077 252 KELIEEKAvKMGVLMLPGNAFYVdsSAPSPYLRASFSSASPEQMdvafQVLAQLIKESL 310
Cdd:PRK15481 378 QATALTLA-KSGWLVREGEAFGV--SAPSHGLRITLSTLNDAEI----NRLAADLHQAL 429
PRK08636 PRK08636
LL-diaminopimelate aminotransferase;
13-265 3.08e-09

LL-diaminopimelate aminotransferase;


Pssm-ID: 236316  Cd Length: 403  Bit Score: 57.41  E-value: 3.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSGTLQSLHPLGCNIINV--------ASDESGIVPDSLRDIlsrwkpeDAKNPQkntPKFLyTVPN 84
Cdd:PRK08636 115 ITNPGDVAIVPDPAYPIHSQAFILAGGNVHKMpleynedfELDEDQFFENLEKAL-------RESSPK---PKYV-VVNF 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  85 GNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSmdVDG-RVIRADSF--SKIIS-SGLRIGFLT 160
Cdd:PRK08636 184 PHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGYKTPSILE--VEGaKDVAVESYtlSKSYNmAGWRVGFVV 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 161 GPKPLIErVILHIQvSTLHPSTFNQLMISQLLhewGEEGFMAHVDRVIDFYSNQKDAILAAADKwltglAEWHV--PAAG 238
Cdd:PRK08636 262 GNKKLVG-ALKKIK-SWLDYGMFTPIQVAATI---ALDGDQSCVEEIRETYRKRRDVLIESFAN-----AGWELqkPRAS 331

                        250       260
                 ....*....|....*....|....*..
gi 767932077 239 MFLWIKvkgindvkelIEEKAVKMGVL 265
Cdd:PRK08636 332 MFVWAK----------IPEPARHLGSL 348
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
13-307 8.71e-09

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 55.91  E-value: 8.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSGTLQSLHPLGCNIINVA--SDESG--IVPDSLRDilsrwkpedakNPQKNTpKFLYTVpNGNNP 88
Cdd:PRK06225 103 FLSPGDNAVTPDPGYLIIDNFASRFGAEVIEVPiySEECNykLTPELVKE-----------NMDENT-RLIYLI-DPLNP 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  89 TGNSLTSERKKEIYELARKYDFLIIEDDPYyflqfNKFRVPTFLSMDVD-GRVIRADSFSKIIS-SGLRIGFLTGPKPLI 166
Cdd:PRK06225 170 LGSSYTEEEIKEFAEIARDNDAFLLHDCTY-----RDFAREHTLAAEYApEHTVTSYSFSKIFGmAGLRIGAVVATPDLI 244

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 167 ErVILHIQVSTLHPSTFNQLMISQLLH---EWgeegfmahVDRVIDFYSNQKDAILAAADKwLTGLAEWHVPAAGMFLWI 243
Cdd:PRK06225 245 E-VVKSIVINDLGTNVIAQEAAIAGLKvkdEW--------IDRIRRTTFKNQKLIKEAVDE-IEGVFLPVYPSHGNMMVI 314

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767932077 244 KVKGINDVKELIEEKAVKMGVLMLPGNafYVDSSAPSPYLRASFsSASPEQMDV---AF-QVLAQLIK 307
Cdd:PRK06225 315 DISEAGIDPEDLVEYLLERKIFVRQGT--YTSKRFGDRYIRVSF-SIPREQVEVfceEFpDVVETLRT 379
PRK06107 PRK06107
aspartate transaminase;
75-290 2.02e-08

aspartate transaminase;


Pssm-ID: 180403  Cd Length: 402  Bit Score: 55.13  E-value: 2.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  75 TPKFLYTVPNG-NNPTGNSLTSERKKEIYE-LARKYDFLIIEDDPYYFLQFNKFRVPTFLSM--DVDGRVIRADSFSKII 150
Cdd:PRK06107 164 TPRTRWLILNApSNPTGAVYSRAELRALADvLLRHPHVLVLTDDIYDHIRFDDEPTPHLLAAapELRDRVLVTNGVSKTY 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 151 S-SGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHewGEEGFMAHVDRVidfYSNQKDAILAAADKwLTGL 229
Cdd:PRK06107 244 AmTGWRIGYAAGPADLIAAINKLQSQSSSCPSSISQAAAAAALN--GDQSFVTESVAV---YKQRRDYALALLNA-IPGL 317

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767932077 230 aEWHVPAAGMFLWIKVKGI------------ND---VKELIEEKavkmGVLMLPGNAFYVdssapSPYLRASFSSA 290
Cdd:PRK06107 318 -SCLVPDGAFYLYVNCAGLigkttpegkvleTDqdvVLYLLDSA----GVAVVQGTAYGL-----SPYFRLSIATS 383
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
 9-305 6.09e-08

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 53.21  E-value: 6.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSgtlqsLHPL-----GCNIINVASDES-GIVPDSLRDILsrwkpedaknpqKNTPKFLYtV 82
Cdd:COG0079   81 LARAFLGPGDEVLVPEPTFS-----EYPIaaraaGAEVVEVPLDEDfSLDLDALLAAI------------TERTDLVF-L 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  83 PNGNNPTGNSLTSERKKEIYELARKYDFLIIeDDPYY-FlqfnkfrVPTFLSM--DVDGR----VIRadSFSKIIS-SGL 154
Cdd:COG0079  143 CNPNNPTGTLLPREELEALLEALPADGLVVV-DEAYAeF-------VPEEDSAlpLLARYpnlvVLR--TFSKAYGlAGL 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 155 RIGFLTGPKPLIE---RVILHIQVSTLhpstfnqlmiSQLLhewgeeGFMAHVDRviDFYSNQKDAILAAADKWLTGLAE 231
Cdd:COG0079  213 RLGYAIASPELIAalrRVRGPWNVNSL----------AQAA------ALAALEDR--AYLEETRARLRAERERLAAALRA 274

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767932077 232 --WHV-PAAGMFLWIKVKGinDVKELiEEKAVKMGVLMLPGNAFYVDSsapspYLRasFSSASPEQMDVAFQVLAQL 305
Cdd:COG0079  275 lgLTVyPSQANFVLVRVPE--DAAEL-FEALLERGILVRDFSSFGLPD-----YLR--ITVGTPEENDRLLAALKEI 341
PLN00145 PLN00145
tyrosine/nicotianamine aminotransferase; Provisional
 84-271 6.11e-08

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 215074 [Multi-domain]  Cd Length: 430  Bit Score: 53.62  E-value: 6.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  84 NGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQF--NKFrVPtflsMDVDGR---VIRADSFSK-IISSGLRIG 157
Cdd:PLN00145 198 NPNNPCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTFgsKPF-VP----MGVFGEvapVLTLGSISKrWVVPGWRLG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 158 FLTGPKP--------LIERVILHIQVSTlHPSTFNQLMISQLLHEWGEEGFmahvDRVIDFYSNQKDaILAAADKWLTGL 229
Cdd:PLN00145 273 WIATCDPngilketkVVDSIRNYLNIST-DPATFVQGAIPQIIANTKEEFF----TKTLGLLKETAD-ICYEKIKEIKCI 346

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 767932077 230 AEWHVPAAGMFLWIKV-----KGINDVKELIEEKAVKMGVLMLPGNA 271
Cdd:PLN00145 347 TCPHKPEGSMFVMVKLdlsclSGIKDDMDFCCKLAKEESVVVLPGSA 393
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
 13-305 1.09e-07

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 52.66  E-value: 1.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   13 IINPGDNVLLDEPAYSgtlqsLHPLGCNIINVASDESGIVPDSLRDilsrwkPEDAKNPQKNTPKFLYtVPNGNNPTGNS 92
Cdd:TIGR01141  92 FLEPGDAVLVPPPTYS-----MYEISAKIHGAEVVKVPLDEDGQLD------LEDILVAIDDKPKLVF-LCSPNNPTGNL 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   93 LTSERKKEIYELARKyDFLIIEDDPYYflQFNKFRVPTFLSMDVDGRVI-RadSFSKIIS-SGLRIGFLTGPKPLIE--- 167
Cdd:TIGR01141 160 FSRGDIEAVLERTPG-DALVVVDEAYG--EFSGEPSTLPLLAEYPNLIVlR--TLSKAFGlAGLRIGYAIANAEIIDaln 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  168 RVILHIQVSTLhpstfNQLMISQLLHEWGEegFMAHVDRVIdfysNQKDAILAAADKwLTGLaEWhVPAAGMFLWIKVKG 247
Cdd:TIGR01141 235 KVRAPFNLSRL-----AQAAAIAALRDDDF--IEATVEEIN----AERERLYDGLKK-LPGL-EV-YPSDANFVLIRFPG 300

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 767932077  248 inDVKELIEEkAVKMGVLMLPGNAFyvdSSAPSPYLRASFssASPEQMDVAFQVLAQL 305
Cdd:TIGR01141 301 --DADALFEA-LLEKGIIVRDLNSY---PGLLPNCLRITV--GTREENDRFLAALREI 350
PRK07550 PRK07550
aminotransferase;
16-305 1.31e-07

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 52.27  E-value: 1.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  16 PGDNVLLDEPAYSGTLQSLHPLGCNIINVASDE-SGIVPDslrdilsrwkPEDAKnpQKNTPK---FLYTVPNgnNPTGN 91
Cdd:PRK07550 113 AGDEVILPLPWYFNHKMWLDMLGIRPVYLPCDEgPGLLPD----------PAAAE--ALITPRtraIALVTPN--NPTGV 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  92 SLTSERKKEIYELARKYDFLIIEDDPYyflqfNKFRVPT------FLSMDVDGRVIRADSFSKIIS-SGLRIGFLTGPKP 164
Cdd:PRK07550 179 VYPPELLHELYDLARRHGIALILDETY-----RDFDSGGgaphdlFADPDWDDTLVHLYSFSKSYAlTGHRVGAVVASPA 253

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 165 LIERvILHIQvSTLhpsTFNQLMISQLLHEWGeegfMAHVDrviDFYSNQKDAILAAADKW---LTGLAEWHVPAAG-MF 240
Cdd:PRK07550 254 RIAE-IEKFM-DTV---AICAPRIGQIAVAWG----LPNLA---DWRAGNRAEIARRRDAFravFARLPGWELLASGaYF 321

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767932077 241 LWIK--VKGINDVkELIEEKAVKMGVLMLPGNAFyvdSSAPSPYLRASFSSASPEQMDVAFQVLAQL 305
Cdd:PRK07550 322 AYVRhpFPDRPSR-EVARRLAKEAGILCLPGTMF---GPGQEGYLRLAFANADVAGIGELVERLRAF 384
PRK08175 PRK08175
aminotransferase; Validated
 13-245 1.78e-07

aminotransferase; Validated


Pssm-ID: 181268 [Multi-domain]  Cd Length: 395  Bit Score: 52.02  E-value: 1.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSgtlqsLHPLGCNIINVASDESGIVPDSlrDILSRWkpEDAKNPQKNTPKFLytVPN-GNNPTGN 91
Cdd:PRK08175 111 TLDHGDTVLVPNPSYP-----IHIYGAVIAGAQVRSVPLVEGV--DFFNEL--ERAIRESYPKPKMM--ILGfPSNPTAQ 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  92 SLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFlsMDVDG-RVIRADSFSKIIS---SGLRIGFLTGPKPLIE 167
Cdd:PRK08175 180 CVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSI--MQVPGaKDVAVEFFTLSKSynmAGWRIGFMVGNPELVS 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 168 rVILHIQvSTLHPSTFNQLMISQLLhewGEEGFMAHVDRVIDFYSNQKDAIlaaadkwLTGLAE--WHV--PAAGMFLWI 243
Cdd:PRK08175 258 -ALARIK-SYHDYGTFTPLQVAAIA---ALEGDQQCVRDIAEQYKRRRDVL-------VKGLHEagWMVemPKASMYVWA 325


                 ..
gi 767932077 244 KV 245
Cdd:PRK08175 326 KI 327
PRK05957 PRK05957
pyridoxal phosphate-dependent aminotransferase;
13-308 2.62e-07

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235654  Cd Length: 389  Bit Score: 51.61  E-value: 2.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESgivpdslrdilsrWKPEDAKNPQKNTPKFLYTV---PngNNPT 89
Cdd:PRK05957 109 ITDPGDEIILNTPYYFNHEMAITMAGCQPILVPTDDN-------------YQLQPEAIEQAITPKTRAIVtisP--NNPT 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  90 GNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfrVPTF--LSM-DVDGRVIRADSFSKIIS-SGLRIGFLTGPKPL 165
Cdd:PRK05957 174 GVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDG--VKHFspGSIpGSGNHTISLYSLSKAYGfASWRIGYMVIPIHL 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 166 IErVILHIQVSTL-HPSTFNQLMISQLLHEwGEEGFMAHVDRVIDFYSNQKDAILAaadkwLTGLAEWHVPAAGMFLWIK 244
Cdd:PRK05957 252 LE-AIKKIQDTILiCPPVVSQYAALGALQV-GKSYCQQHLPEIAQVRQILLKSLGQ-----LQDRCTLHPANGAFYCFLK 324

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767932077 245 VK-GIND---VKELIEEkavkMGVLMLPGNAFYVDSSApspYLRASFSSASPEQMDVAFQVLAQLIKE 308
Cdd:PRK05957 325 VNtDLNDfelVKQLIRE----YRVAVIPGTTFGMKNGC---YLRIAYGALQKATAKEGIERLVQGLKT 385
PRK07337 PRK07337
pyridoxal phosphate-dependent aminotransferase;
13-178 2.99e-07

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180937  Cd Length: 388  Bit Score: 51.21  E-value: 2.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYsgtlqslhPLGCNIINVASDESGIVPDSL--RDILSRWKPEDAKNPqkNTPKFLYTVPngNNPTG 90
Cdd:PRK07337 110 LVERGDEVLMPDPSY--------PCNRHFVAAAEGRPVLVPSGPaeRFQLTAADVEAAWGE--RTRGVLLASP--SNPTG 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  91 NSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVpTFLSMDVDgrVIRADSFSKIIS-SGLRIGFLTGPKPL---I 166
Cdd:PRK07337 178 TSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAPV-SALSLGDD--VITINSFSKYFNmTGWRLGWLVVPEALvgtF 254

                        170
                 ....*....|....
gi 767932077 167 ERVI--LHIQVSTL 178
Cdd:PRK07337 255 EKLAqnLFICASAL 268
PRK07683 PRK07683
aminotransferase A; Validated
 10-170 5.04e-07

aminotransferase A; Validated


Pssm-ID: 236075  Cd Length: 387  Bit Score: 50.49  E-value: 5.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  10 FEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIvpdslrdILSRWKPEDAKNPQKNTpkflYTVPNGNNPT 89
Cdd:PRK07683 106 FRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTRSTGF-------RLTAEALENAITEKTRC----VVLPYPSNPT 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  90 GNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNK--FRVPTFLSMDVDGRVIraDSFSKIIS-SGLRIGFLTGPKPLI 166
Cdd:PRK07683 175 GVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQphTSIAHFPEMREKTIVI--NGLSKSHSmTGWRIGFLFAPSYLA 252


                 ....
gi 767932077 167 ERVI 170
Cdd:PRK07683 253 KHIL 256
PRK05839 PRK05839
succinyldiaminopimelate transaminase;
86-269 2.00e-06

succinyldiaminopimelate transaminase;


Pssm-ID: 180281  Cd Length: 374  Bit Score: 48.92  E-value: 2.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  86 NNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfRVPTFL--SMDVDGR----VIRADSFSKIISS-GLRIGF 158
Cdd:PRK05839 165 NNPTGRTLSLEELIEWVKLALKHDFILINDECYSEIYENT-PPPSLLeaSILVGNEsfknVLVINSISKRSSApGLRSGF 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 159 LTGPKPLIERVILHiqvstlhpSTFNQLMISQLLHE-----WGEegfMAHVDRVIDFYSNQkdaiLAAADKWLtglaEWH 233
Cdd:PRK05839 244 IAGDASILKKYKAY--------RTYLGCASPLPLQKaaavaWLD---DEHAEFFRNIYAKN----LKLAREIL----GIT 304

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 767932077 234 VPAAGMFLWIKVK-GINDVKELIEEKavkmGVLMLPG 269
Cdd:PRK05839 305 IPPATFYVWLPVDnDEEFTKKLYQNE----GIKVLPG 337
PLN02656 PLN02656
tyrosine transaminase
 84-300 2.82e-06

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 48.38  E-value: 2.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  84 NGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNkfRVPtFLSMDVDGR---VIRADSFSK-IISSGLRIGFL 159
Cdd:PLN02656 177 NPGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFG--SNP-FVPMGVFGSivpVLTLGSLSKrWIVPGWRLGWF 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 160 TGPKP--------LIERVILHIQVSTlHPSTFNQLMISQLLHEWGEEGFmahvDRVIDFYSNQKDaILAAADKWLTGLAE 231
Cdd:PLN02656 254 VTTDPsgsfrdpkIVERIKKYFDILG-GPATFIQAAVPTILEQTDESFF----KKTINILKQSSD-ICCDRIKEIPCITC 327

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767932077 232 WHVPAAGMFLWIK-----VKGINDVKELIEEKAVKMGVLMLPGNAFYVDSsapspYLRASFsSASPEQMDVAFQ 300
Cdd:PLN02656 328 PHKPEGSMAVMVKlnlslLEDISDDIDFCFKLAREESVIILPGTAVGLKN-----WLRITF-AADPSSLEEALG 395
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
 11-272 4.36e-06

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 47.86  E-value: 4.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   11 EMIINPGDNVLLDEPAYS--GTLQSLHPLGCNIINVASDES-GIVPDSLRDILSrwkpedaknpqKNTPKFLytVPNGNN 87
Cdd:TIGR01264 113 AALANAGQNILVPRPGFPlyETLAESMGIEVKLYNLLPDKSwEIDLKQLESLID-----------EKTAALI--VNNPSN 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   88 PTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSK-IISSGLRIG--------- 157
Cdd:TIGR01264 180 PCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGATFEPLASLSSTVPILSCGGLAKrWLVPGWRLGwiiihdrrg 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  158 ----FLTGPKPLIERVilhiqvstLHPSTFNQLMISQLLHEWGEEGFMAHVDrVIDFYSNQKDAILAAadkwLTGLAEwH 233
Cdd:TIGR01264 260 ilrdIRDGLVKLSQRI--------LGPCTIVQGALPSILLRTPQEYFDGTLS-VLESNAMLCYGALAA----VPGLRP-V 325

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 767932077  234 VPAAGMFLWIKV------KGINDV---KELIEEKAVKmgvlMLPGNAF 272
Cdd:TIGR01264 326 MPSGAMYMMVGIemehfpEFKNDVeftERLVAEQSVF----CLPGSCF 369
PRK07366 PRK07366
LL-diaminopimelate aminotransferase;
13-272 5.84e-06

LL-diaminopimelate aminotransferase;


Pssm-ID: 180947  Cd Length: 388  Bit Score: 47.37  E-value: 5.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSGTLQSLHPLGCNIINVA-SDESGIVPDsLRDIlsrwkPEDAKNPQKntpkfLYTVPNGNNPTGN 91
Cdd:PRK07366 112 VLNPGDFALLLDPGYPSHAGGVYLAGGQIYPMPlRAENDFLPV-FADI-----PTEVLAQAR-----LMVLSYPHNPTTA 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  92 SLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFR-VPTFLSMDVDGRV-IRADSFSKIIS-SGLRIGFLTGPKPLIeR 168
Cdd:PRK07366 181 IAPLSFFQEAVAFCQQHDLVLVHDFPYVDLVFDGEVePPSILQADPEKSVsIEFFTLSKSYNmGGFRIGFAIGNAQLI-Q 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 169 VILHIQVSTlhpsTFNQLM------ISQLlhewgeEGFMAHVDRVIDFYSNQKDAILAAADKwltglAEWHV--PAAGMF 240
Cdd:PRK07366 260 ALRQVKAVV----DFNQYRgilngaIAAL------TGPQATVQQTVQIFRQRRDAFINALHQ-----IGWPVplPEATMY 324

                        250       260       270
                 ....*....|....*....|....*....|....
gi 767932077 241 LWIKVKGI--NDVKELIEEKAVKMGVLMLPGNAF 272
Cdd:PRK07366 325 VWAKLPEPwqGNSVEFCTQLVAQTGVAASPGSGF 358
PRK09147 PRK09147
succinyldiaminopimelate transaminase; Provisional
 86-269 6.82e-06

succinyldiaminopimelate transaminase; Provisional


Pssm-ID: 236393  Cd Length: 396  Bit Score: 47.18  E-value: 6.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  86 NNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLsMDVDGRVIRAD--------SFSKiiSS---GL 154
Cdd:PRK09147 176 GNPTGAVLPLDDWKKLFALSDRYGFVIASDECYSEIYFDEAAPPLGL-LEAAAELGRDDfkrlvvfhSLSK--RSnvpGL 252

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 155 RIGFLTGPKPLIERVILHiqvSTLHPSTFNqlMISQL--LHEWGEEgfmAHVDRVIDFYSNQKDAILAAadkwLTGLAEW 232
Cdd:PRK09147 253 RSGFVAGDAALLKKFLLY---RTYHGCAMP--PAVQAasIAAWNDE---AHVRENRALYREKFDAVTPI----LAPVLDV 320

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 767932077 233 HVPAAGMFLWIKVKGiND---VKELIEEKAVKmgvlMLPG 269
Cdd:PRK09147 321 QLPDAGFYLWAKVPG-DDtefARRLYADYNVT----VLPG 355
PRK06207 PRK06207
pyridoxal phosphate-dependent aminotransferase;
78-207 7.54e-06

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235742  Cd Length: 405  Bit Score: 47.07  E-value: 7.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  78 FLYTVPNgnNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDG-RVIRADSFSKIIS-SGLR 155
Cdd:PRK06207 182 FLFSNPN--NPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDGTSYTHLRALPIDPeNVITIMGPSKTESlSGYR 259

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767932077 156 IGFLTGPKPLIERVILHIQVSTLHPSTFNQlmisQLLHEWGEE--GFMAhvDRV 207
Cdd:PRK06207 260 LGVAFGSPAIIDRMEKLQAIVSLRAAGYSQ----AVLRTWFSEpdGWMK--DRI 307
PLN00175 PLN00175
aminotransferase family protein; Provisional
 13-287 7.72e-06

aminotransferase family protein; Provisional


Pssm-ID: 215089 [Multi-domain]  Cd Length: 413  Bit Score: 47.17  E-value: 7.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSGTLQSLHPLGCNI--INVASDESGIVPDSLRDILSrwkpedaknpqKNTPKFLYTVPNgnNPTG 90
Cdd:PLN00175 135 LINPGDEVILFAPFYDSYEATLSMAGAKIktVTLRPPDFAVPEDELKAAFT-----------SKTRAILINTPH--NPTG 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  91 NSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVptflSM-DVDG---RVIRADSFSKIIS-SGLRIGFLTGPKPL 165
Cdd:PLN00175 202 KMFTREELELIASLCKENDVLAFTDEVYDKLAFEGDHI----SMaSLPGmyeRTVTMNSLGKTFSlTGWKIGWAIAPPHL 277

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 166 IERVILHIQVSTLHPSTFNQlmisqllheWGEEGFMAHVDrviDFYSNQKDAILAAADKWLTGLAE--WHV-PAAGMFlW 242
Cdd:PLN00175 278 TWGVRQAHSFLTFATATPMQ---------WAAVAALRAPE---SYYEELKRDYSAKKDILVEGLKEvgFKVyPSSGTY-F 344

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767932077 243 IKVK----GI-NDV---KELIEEkavkMGVLMLPGNAFYVDSSAPSPYLRASF 287
Cdd:PLN00175 345 VMVDhtpfGFeNDIafcEYLIEE----VGVAAIPPSVFYLNPEDGKNLVRFAF 393
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
9-288 4.96e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 44.41  E-value: 4.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEP------AYSGTlqslHplGCNIINVASDESGIVPDsLRDIlsrwkpEDAKNPQK-----NTPk 77
Cdd:PRK06836 112 ALKAILNPGDEVIVFAPyfveyrFYVDN----H--GGKLVVVPTDTDTFQPD-LDAL------EAAITPKTkaviiNSP- 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  78 flytvpngNNPTGNSLTSERKKEIYELARK------YDFLIIEDDPYYFLQFNKFRVPTFLSMdVDgRVIRADSFSKIIS 151
Cdd:PRK06836 178 --------NNPTGVVYSEETLKALAALLEEkskeygRPIYLISDEPYREIVYDGAEVPYIFKY-YD-NSIVVYSFSKSLS 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 152 -SGLRIGFL------TGPKPLIE------RVILHIQVstlhPSTFnQLMISQLLHEwgeegfmaHVDrvIDFYSNQKDAI 218
Cdd:PRK06836 248 lPGERIGYIavnpemEDADDLVAalvfanRILGFVNA----PALM-QRVVAKCLDA--------TVD--VSIYKRNRDLL 312

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767932077 219 LAAadkwLTGLA-EWHVPAAGMFLWIKVKGINDVKELieEKAVKMGVLMLPGNAFyvdsSAPSpYLRASFS 288
Cdd:PRK06836 313 YDG----LTELGfECVKPQGAFYLFPKSPEEDDVAFC--EKAKKHNLLLVPGSGF----GCPG-YFRLSYC 372
PLN00143 PLN00143
tyrosine/nicotianamine aminotransferase; Provisional
 7-288 2.48e-04

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 165711 [Multi-domain]  Cd Length: 409  Bit Score: 42.31  E-value: 2.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   7 EKVFEMIINPGDNVLLDEPAYSgtlqsLHPLGCNIINVASDESGIVPDSlrdilsRWKPE-DAKNPQKNTPKFLYTVPNG 85
Cdd:PLN00143 111 EIIIKVLARPEANILLPRPGFP-----DVETYAIFHHLEIRHFDLLPEK------GWEVDlDAVEAIADENTIAMVIINP 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  86 NNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfrvPTFLSMDVDGR---VIRADSFSK-IISSGLRIGFLTG 161
Cdd:PLN00143 180 GNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGS---KPFVPMGLFASivpVITLGSISKrWMIPGWGLGWLVT 256

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077 162 PKPL-------IERVILHIQVSTLHPSTFNQLMISQLLHEWGEegfmahvdrviDFYSNQKDAILAAADKWLTGLAEW-- 232
Cdd:PLN00143 257 CDPSgllqiceIADSIKKALNPAPFPPTFIQAAIPEILEKTTE-----------DFFSKTINILRAALAFCYDKLKEIpc 325

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767932077 233 ----HVPAAGMFLWIK-----VKGINDVKELIEEKAVKMGVLMLPGNAFYVDSsapspYLRASFS 288
Cdd:PLN00143 326 imcpQKAEGAFFALVKlnlllLEDIEDDMEFCLKLAKEESLIILPGVTVGLKN-----WLRITFA 385
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 13-118 1.00e-03

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 40.49  E-value: 1.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYsgtlqslhPLGCNIINVASdesGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVP-NGNNPTGN 91
Cdd:PRK13355 228 LLDDGDEVLIPSPDY--------PLWTACVNLAG---GTAVHYRCDEQSEWYPDIDDIRSKITSRTKAIVIiNPNNPTGA 296

                         90       100
                 ....*....|....*....|....*..
gi 767932077  92 SLTSERKKEIYELARKYDFLIIEDDPY 118
Cdd:PRK13355 297 LYPREVLQQIVDIAREHQLIIFSDEIY 323
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
 9-189 1.11e-03

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 40.33  E-value: 1.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMII-NPGDNVLL---DEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILsrwkpEDAKNpQKNTPKFLyTVPN 84
Cdd:PTZ00377 154 LLQLLIgDPSDGVMIpipQYPLYSAAITLLGGKQVPYYLDEEKGWSLDQEELEEAY-----EQAVR-NGITPRAL-VVIN 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  85 GNNPTGNSLTSERKKEIYELARKYDFLIIEDDPY----Y-----FLQFNKFRvptfLSMDVDGRV----IRADSFSKII- 150
Cdd:PTZ00377 227 PGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYqeniYdgekpFISFRKVL----LELPAEYNTdvelVSFHSTSKGIi 302

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 767932077 151 -SSGLRIGF--LTGPKPLIERVILHIQVSTLHPSTFNQLMIS 189
Cdd:PTZ00377 303 gECGRRGGYfeLTNIPPEVREQIYKLASINLCSNVVGQLMTG 344
AAT_I cd01494
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ...
 9-118 1.71e-03

Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).


Pssm-ID: 99742 [Multi-domain]  Cd Length: 170  Bit Score: 38.52  E-value: 1.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077   9 VFEMIINPGDNVLLDEPAYSGTLQS-LHPLGCNIINVASDESGIVPDSLrDILSRWKPEDaknpqknTPKFLYTVPNGNN 87
Cdd:cd01494   33 ALLALLGPGDEVIVDANGHGSRYWVaAELAGAKPVPVPVDDAGYGGLDV-AILEELKAKP-------NVALIVITPNTTS 104

                         90       100       110
                 ....*....|....*....|....*....|.
gi 767932077  88 PTGNsltsERKKEIYELARKYDFLIIEDDPY 118
Cdd:cd01494  105 GGVL----VPLKEIRKIAKEYGILLLVDAAS 131
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
13-185 6.78e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 37.73  E-value: 6.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  13 IINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEdaknpqknTPKFLYTVPngNNPTGNS 92
Cdd:PRK08960 112 LVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSRYQLTPALVERHWNAD--------TVGALVASP--ANPTGTL 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932077  93 LTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfRVPTFLSMDVDGRVIraDSFSKIIS-SGLRIGFLTGPKPLIERVIL 171
Cdd:PRK08960 182 LSRDELAALSQALRARGGHLVVDEIYHGLTYGV-DAASVLEVDDDAFVL--NSFSKYFGmTGWRLGWLVAPPAAVPELEK 258

                        170
                 ....*....|....
gi 767932077 172 HIQVSTLHPSTFNQ 185
Cdd:PRK08960 259 LAQNLYISASTPAQ 272
PRK06855 PRK06855
pyridoxal phosphate-dependent aminotransferase;
84-140 7.79e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180734  Cd Length: 433  Bit Score: 37.62  E-value: 7.79e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767932077  84 NGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKfRVPTFLSmDVDGRV 140
Cdd:PRK06855 179 NPDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNG-KKTVPLS-EVIGDV 233
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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