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Conserved domains on  [gi|767924680|ref|XP_011532571|]
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transcription cofactor vestigial-like protein 4 isoform X4 [Homo sapiens]

Protein Classification

VGLL4 and TDU domain-containing protein( domain architecture ID 10633645)

VGLL4 and TDU domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
VGLL4 pfam15245
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
1-165 1.18e-73

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


:

Pssm-ID: 464585  Cd Length: 216  Bit Score: 222.81  E-value: 1.18e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767924680    1 MEPGDEDLDcDNDHVSKMSRIFNPHLNKtANGDCRRDPRERSRSPIERAVAPTMSLHGSHLYTSLPSLGLEQPLALTKNS 80
Cdd:pfam15245  56 GEQGDDDFD-DNEHVAKMSRLFATQLGK-SNGDYRQEHFSRSRSPIERATAPSTSLHPNHLYASPPSYAMDQPLALTKNS 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767924680   81 L-DASRPAGLSPTLTPGERQQNRPSVITCASAGARNCNLSHCPIahSGCAAPgPASYRRPPSAATTCDPVVEEHFRRSLG 159
Cdd:pfam15245 134 MkDSARTAEISPTSGAVERQQNRPSVITCAPASNRNCNLSHCPV--NGCPSL-PPDYRRSSSTNTACDPVIEEHFRRSLG 210

                  ....*.
gi 767924680  160 KNYKEP 165
Cdd:pfam15245 211 KNYKEP 216
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
175-190 4.85e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


:

Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.30  E-value: 4.85e-04
                           10
                   ....*....|....*.
gi 767924680   175 TGSVDDHFAKALGDTW 190
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
 
Name Accession Description Interval E-value
VGLL4 pfam15245
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
1-165 1.18e-73

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


Pssm-ID: 464585  Cd Length: 216  Bit Score: 222.81  E-value: 1.18e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767924680    1 MEPGDEDLDcDNDHVSKMSRIFNPHLNKtANGDCRRDPRERSRSPIERAVAPTMSLHGSHLYTSLPSLGLEQPLALTKNS 80
Cdd:pfam15245  56 GEQGDDDFD-DNEHVAKMSRLFATQLGK-SNGDYRQEHFSRSRSPIERATAPSTSLHPNHLYASPPSYAMDQPLALTKNS 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767924680   81 L-DASRPAGLSPTLTPGERQQNRPSVITCASAGARNCNLSHCPIahSGCAAPgPASYRRPPSAATTCDPVVEEHFRRSLG 159
Cdd:pfam15245 134 MkDSARTAEISPTSGAVERQQNRPSVITCAPASNRNCNLSHCPV--NGCPSL-PPDYRRSSSTNTACDPVIEEHFRRSLG 210

                  ....*.
gi 767924680  160 KNYKEP 165
Cdd:pfam15245 211 KNYKEP 216
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
147-162 3.72e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.69  E-value: 3.72e-04
                           10
                   ....*....|....*.
gi 767924680   147 DPVVEEHFRRSLGKNY 162
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
175-190 4.85e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.30  E-value: 4.85e-04
                           10
                   ....*....|....*.
gi 767924680   175 TGSVDDHFAKALGDTW 190
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
 
Name Accession Description Interval E-value
VGLL4 pfam15245
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
1-165 1.18e-73

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


Pssm-ID: 464585  Cd Length: 216  Bit Score: 222.81  E-value: 1.18e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767924680    1 MEPGDEDLDcDNDHVSKMSRIFNPHLNKtANGDCRRDPRERSRSPIERAVAPTMSLHGSHLYTSLPSLGLEQPLALTKNS 80
Cdd:pfam15245  56 GEQGDDDFD-DNEHVAKMSRLFATQLGK-SNGDYRQEHFSRSRSPIERATAPSTSLHPNHLYASPPSYAMDQPLALTKNS 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767924680   81 L-DASRPAGLSPTLTPGERQQNRPSVITCASAGARNCNLSHCPIahSGCAAPgPASYRRPPSAATTCDPVVEEHFRRSLG 159
Cdd:pfam15245 134 MkDSARTAEISPTSGAVERQQNRPSVITCAPASNRNCNLSHCPV--NGCPSL-PPDYRRSSSTNTACDPVIEEHFRRSLG 210

                  ....*.
gi 767924680  160 KNYKEP 165
Cdd:pfam15245 211 KNYKEP 216
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
147-162 3.72e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.69  E-value: 3.72e-04
                           10
                   ....*....|....*.
gi 767924680   147 DPVVEEHFRRSLGKNY 162
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
175-190 4.85e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.30  E-value: 4.85e-04
                           10
                   ....*....|....*.
gi 767924680   175 TGSVDDHFAKALGDTW 190
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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