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Conserved domains on  [gi|767978270|ref|XP_011533616|]
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epithelial-stromal interaction protein 1 isoform X4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
cdk7 super family cl31015
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions ...
 53-202 8.18e-03

CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions are known are cyclin dependent protein kinases that are components of TFIIH, a complex that is involved in nucleotide excision repair and transcription initiation. Also known as MAT1 (menage a trois 1). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


The actual alignment was detected with superfamily member TIGR00570:

Pssm-ID: 129661 [Multi-domain]  Cd Length: 309  Bit Score: 36.71  E-value: 8.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978270   53 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEH------RRVNNAFLDRLQGKSQPGGLEQSGGCW 126
Cdd:TIGR00570 124 TYQKENKDVIQKNKEKSTREQEELEEALEFEKEEEEQRRLLLQKEEEeqqmnkRKNKQALLDELETSTLPAAELIAQHKK 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978270  127 NmnsgnswgsllvfSRHLRVYEKILTPIWPS--STDLEKPHEMLFLNV-----ILFSLTVFTLISTAH---TLDRAVRSD 196
Cdd:TIGR00570 204 N-------------SVKLEMQVEKPKPEKPNtfSTGIKMGYQISLVPVqkseeALYPYQPLNIETEGPpvpTLEELVRQG 270


                  ....*.
gi 767978270  197 WLLLVL 202
Cdd:TIGR00570 271 YLNHVR 276
 
Name Accession Description Interval E-value
cdk7 TIGR00570
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions ...
 53-202 8.18e-03

CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions are known are cyclin dependent protein kinases that are components of TFIIH, a complex that is involved in nucleotide excision repair and transcription initiation. Also known as MAT1 (menage a trois 1). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129661 [Multi-domain]  Cd Length: 309  Bit Score: 36.71  E-value: 8.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978270   53 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEH------RRVNNAFLDRLQGKSQPGGLEQSGGCW 126
Cdd:TIGR00570 124 TYQKENKDVIQKNKEKSTREQEELEEALEFEKEEEEQRRLLLQKEEEeqqmnkRKNKQALLDELETSTLPAAELIAQHKK 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978270  127 NmnsgnswgsllvfSRHLRVYEKILTPIWPS--STDLEKPHEMLFLNV-----ILFSLTVFTLISTAH---TLDRAVRSD 196
Cdd:TIGR00570 204 N-------------SVKLEMQVEKPKPEKPNtfSTGIKMGYQISLVPVqkseeALYPYQPLNIETEGPpvpTLEELVRQG 270


                  ....*.
gi 767978270  197 WLLLVL 202
Cdd:TIGR00570 271 YLNHVR 276
 
Name Accession Description Interval E-value
cdk7 TIGR00570
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions ...
 53-202 8.18e-03

CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions are known are cyclin dependent protein kinases that are components of TFIIH, a complex that is involved in nucleotide excision repair and transcription initiation. Also known as MAT1 (menage a trois 1). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129661 [Multi-domain]  Cd Length: 309  Bit Score: 36.71  E-value: 8.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978270   53 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEH------RRVNNAFLDRLQGKSQPGGLEQSGGCW 126
Cdd:TIGR00570 124 TYQKENKDVIQKNKEKSTREQEELEEALEFEKEEEEQRRLLLQKEEEeqqmnkRKNKQALLDELETSTLPAAELIAQHKK 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978270  127 NmnsgnswgsllvfSRHLRVYEKILTPIWPS--STDLEKPHEMLFLNV-----ILFSLTVFTLISTAH---TLDRAVRSD 196
Cdd:TIGR00570 204 N-------------SVKLEMQVEKPKPEKPNtfSTGIKMGYQISLVPVqkseeALYPYQPLNIETEGPpvpTLEELVRQG 270


                  ....*.
gi 767978270  197 WLLLVL 202
Cdd:TIGR00570 271 YLNHVR 276
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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