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Conserved domains on  [gi|767963189|ref|XP_011538221|]
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centrosomal protein of 55 kDa isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
EABR pfam12180
TSG101 and ALIX binding domain of CEP55; This domain family is found in eukaryotes, and is ...
2-35 4.96e-08

TSG101 and ALIX binding domain of CEP55; This domain family is found in eukaryotes, and is approximately 40 amino acids in length. This domain is the active domain of CEP55. CEP55 is a protein involved in cytokinesis, specifically in abscission of the plasma membrane at the midbody. To perform this function, CEP55 complexes with ESCRT-I (by a Proline rich sequence in its TSG101 domain) and ALIX. This is the domain on CEP55 which binds to both TSG101 and ALIX. It also acts as a hinge between the N and C termini. This domain is called EABR.


:

Pssm-ID: 463486 [Multi-domain]  Cd Length: 34  Bit Score: 48.26  E-value: 4.96e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 767963189    2 EIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFE 35
Cdd:pfam12180   1 KQQVADVLELNQQWQVYDQSREEYVRGLLARLKE 34
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
61-227 1.58e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 1.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189    61 QEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFR-------RKYEETQKEVHNLNQL---LYSQRRADVQHLEDDRH 130
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEELRlevseleEEIEELQKELYALANEisrLEQQKQILRERLANLER 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189   131 KTEKIQKLREENDIARGKLEEEKKRSEELLSQVQFLYTSLLKQQEEQTRV-ALLEQQMQACTLDFENEKLDRQHVQHQLH 209
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAElEELESRLEELEEQLETLRSKVAQLELQIA 396
                          170
                   ....*....|....*...
gi 767963189   210 VILKELRKARNQITQLES 227
Cdd:TIGR02168  397 SLNNEIERLEARLERLED 414
 
Name Accession Description Interval E-value
EABR pfam12180
TSG101 and ALIX binding domain of CEP55; This domain family is found in eukaryotes, and is ...
2-35 4.96e-08

TSG101 and ALIX binding domain of CEP55; This domain family is found in eukaryotes, and is approximately 40 amino acids in length. This domain is the active domain of CEP55. CEP55 is a protein involved in cytokinesis, specifically in abscission of the plasma membrane at the midbody. To perform this function, CEP55 complexes with ESCRT-I (by a Proline rich sequence in its TSG101 domain) and ALIX. This is the domain on CEP55 which binds to both TSG101 and ALIX. It also acts as a hinge between the N and C termini. This domain is called EABR.


Pssm-ID: 463486 [Multi-domain]  Cd Length: 34  Bit Score: 48.26  E-value: 4.96e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 767963189    2 EIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFE 35
Cdd:pfam12180   1 KQQVADVLELNQQWQVYDQSREEYVRGLLARLKE 34
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
61-227 1.58e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 1.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189    61 QEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFR-------RKYEETQKEVHNLNQL---LYSQRRADVQHLEDDRH 130
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEELRlevseleEEIEELQKELYALANEisrLEQQKQILRERLANLER 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189   131 KTEKIQKLREENDIARGKLEEEKKRSEELLSQVQFLYTSLLKQQEEQTRV-ALLEQQMQACTLDFENEKLDRQHVQHQLH 209
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAElEELESRLEELEEQLETLRSKVAQLELQIA 396
                          170
                   ....*....|....*...
gi 767963189   210 VILKELRKARNQITQLES 227
Cdd:TIGR02168  397 SLNNEIERLEARLERLED 414
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
60-255 2.53e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 2.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  60 LQEEKQKcYNDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLR 139
Cdd:COG1196  237 LEAELEE-LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189 140 EEndiargkLEEEKKRSEELLSQVQFLYTSLLKQQEEQtrvALLEQQMQACTLDFENEKLDRQHVQHQLHVILKELRKAR 219
Cdd:COG1196  316 ER-------LEELEEELAELEEELEELEEELEELEEEL---EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 767963189 220 NQITQLESLKQLHEFAITEPLVTFQGETENREKVAA 255
Cdd:COG1196  386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421
PTZ00121 PTZ00121
MAEBL; Provisional
35-267 3.31e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.97  E-value: 3.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189   35 ELEKKTETAAHSLPQQTKKPESEGYLQEEKQKcyndLLASAKKDLEVERQTITQLSFELSEFRRKYEETQK-EVHNLNQL 113
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK----IKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKaEEENKIKA 1663
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  114 LYSQRRADVQHL---------EDDRHKTEKIQKLREENDIA---RGKLEEEKKRSEEL--LSQVQFLYTSLLKQQEEQTR 179
Cdd:PTZ00121 1664 AEEAKKAEEDKKkaeeakkaeEDEKKAAEALKKEAEEAKKAeelKKKEAEEKKKAEELkkAEEENKIKAEEAKKEAEEDK 1743
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  180 VALLEQQMQactldfENEKLDRQHVQHQLHVILKELRKARNQITQlESLKQLHEFAITEPLVTFQGETENREKVAASPKS 259
Cdd:PTZ00121 1744 KKAEEAKKD------EEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816

                  ....*...
gi 767963189  260 PTAALNES 267
Cdd:PTZ00121 1817 GNLVINDS 1824
 
Name Accession Description Interval E-value
EABR pfam12180
TSG101 and ALIX binding domain of CEP55; This domain family is found in eukaryotes, and is ...
2-35 4.96e-08

TSG101 and ALIX binding domain of CEP55; This domain family is found in eukaryotes, and is approximately 40 amino acids in length. This domain is the active domain of CEP55. CEP55 is a protein involved in cytokinesis, specifically in abscission of the plasma membrane at the midbody. To perform this function, CEP55 complexes with ESCRT-I (by a Proline rich sequence in its TSG101 domain) and ALIX. This is the domain on CEP55 which binds to both TSG101 and ALIX. It also acts as a hinge between the N and C termini. This domain is called EABR.


Pssm-ID: 463486 [Multi-domain]  Cd Length: 34  Bit Score: 48.26  E-value: 4.96e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 767963189    2 EIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFE 35
Cdd:pfam12180   1 KQQVADVLELNQQWQVYDQSREEYVRGLLARLKE 34
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
61-227 1.58e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 1.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189    61 QEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFR-------RKYEETQKEVHNLNQL---LYSQRRADVQHLEDDRH 130
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEELRlevseleEEIEELQKELYALANEisrLEQQKQILRERLANLER 316
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189   131 KTEKIQKLREENDIARGKLEEEKKRSEELLSQVQFLYTSLLKQQEEQTRV-ALLEQQMQACTLDFENEKLDRQHVQHQLH 209
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAElEELESRLEELEEQLETLRSKVAQLELQIA 396
                          170
                   ....*....|....*...
gi 767963189   210 VILKELRKARNQITQLES 227
Cdd:TIGR02168  397 SLNNEIERLEARLERLED 414
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
60-255 2.53e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 2.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  60 LQEEKQKcYNDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLR 139
Cdd:COG1196  237 LEAELEE-LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189 140 EEndiargkLEEEKKRSEELLSQVQFLYTSLLKQQEEQtrvALLEQQMQACTLDFENEKLDRQHVQHQLHVILKELRKAR 219
Cdd:COG1196  316 ER-------LEELEEELAELEEELEELEEELEELEEEL---EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 767963189 220 NQITQLESLKQLHEFAITEPLVTFQGETENREKVAA 255
Cdd:COG1196  386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
69-230 3.66e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 3.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  69 NDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLySQRRADVQHLEDDRHKTEK-IQKLREENDIARG 147
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAeLAELEKEIAELRA 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189 148 KLEEEKKRSEELLSQVQFL----YTSLLKQQEE----QTRVALLEQQMQACTLDFENEKLDRQHVQHQLHVILKELRKAR 219
Cdd:COG4942   98 ELEAQKEELAELLRALYRLgrqpPLALLLSPEDfldaVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
                        170
                 ....*....|.
gi 767963189 220 NQITQLESLKQ 230
Cdd:COG4942  178 ALLAELEEERA 188
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
4-226 3.81e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 3.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189     4 QLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEVER 83
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE 788
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189    84 QTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREEndiARGKLEEEKKRSEELLSQV 163
Cdd:TIGR02168  789 AQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ---IEELSEDIESLAAEIEELE 865
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767963189   164 QFLYTSLLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLHVILKELRKARNQITQLE 226
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
72-240 4.61e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.85  E-value: 4.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  72 LASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEE 151
Cdd:COG1196  234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189 152 EKKRSEELLSQvqflytsllkQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLHVILKELRKARNQITQLESLKQL 231
Cdd:COG1196  314 LEERLEELEEE----------LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                 ....*....
gi 767963189 232 HEFAITEPL 240
Cdd:COG1196  384 LAEELLEAL 392
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
26-166 1.25e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 40.23  E-value: 1.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  26 VKGL-LAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCyndllasAKKDLEVERqtitqLSFELSEFRRKYEETQ 104
Cdd:COG2433  373 IRGLsIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEI-------RRLEEQVER-----LEAEVEELEAELEEKD 440
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767963189 105 KEVHNLNQLLYSQRRADVQHLEDDRhkteKIQKLREENDIARGKLEEEKKRSEELLSQVQFL 166
Cdd:COG2433  441 ERIERLERELSEARSEERREIRKDR----EISRLDREIERLERELEEERERIEELKRKLERL 498
PTZ00121 PTZ00121
MAEBL; Provisional
35-267 3.31e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.97  E-value: 3.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189   35 ELEKKTETAAHSLPQQTKKPESEGYLQEEKQKcyndLLASAKKDLEVERQTITQLSFELSEFRRKYEETQK-EVHNLNQL 113
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK----IKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKaEEENKIKA 1663
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  114 LYSQRRADVQHL---------EDDRHKTEKIQKLREENDIA---RGKLEEEKKRSEEL--LSQVQFLYTSLLKQQEEQTR 179
Cdd:PTZ00121 1664 AEEAKKAEEDKKkaeeakkaeEDEKKAAEALKKEAEEAKKAeelKKKEAEEKKKAEELkkAEEENKIKAEEAKKEAEEDK 1743
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  180 VALLEQQMQactldfENEKLDRQHVQHQLHVILKELRKARNQITQlESLKQLHEFAITEPLVTFQGETENREKVAASPKS 259
Cdd:PTZ00121 1744 KKAEEAKKD------EEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816

                  ....*...
gi 767963189  260 PTAALNES 267
Cdd:PTZ00121 1817 GNLVINDS 1824
PTZ00121 PTZ00121
MAEBL; Provisional
37-251 8.38e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 37.81  E-value: 8.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189   37 EKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYS 116
Cdd:PTZ00121 1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA 1508
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  117 QRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRSEEL-----LSQVQFLYTSLLKQQEEQTRVALLEQQMQACT 191
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELkkaeeLKKAEEKKKAEEAKKAEEDKNMALRKAEEAKK 1588
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767963189  192 LDFENEKLDRQHVQHQLHVILKELRKARNQITQLESLKQLHEFAITEPLVTFQGETENRE 251
Cdd:PTZ00121 1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK 1648
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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