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Conserved domains on  [gi|767902478|ref|XP_011539031|]
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collagen alpha-1(XVI) chain isoform X15 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TSPN smart00210
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of ...
50-231 5.08e-59

Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of thrombospondin


:

Pssm-ID: 214560  Cd Length: 184  Bit Score: 200.66  E-value: 5.08e-59
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478     50 GFNLIHRLSLM-KTSAIKKIRNPKGP-LILRLG-AAPVTQPTRRVFPRGLPEEFALVLTLLLKKhthQKTWYLFQVTDAN 126
Cdd:smart00210    1 GQDLLQVFDLPsLSFAIRQVVGPEPGsPAYRLGdPALVPQPTRDLFPSGLPEDFSLLTTFRQTP---KSRGVLFAIYDAQ 77
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478    127 GYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRR--PMRPVG 204
Cdd:smart00210   78 NVRQFGLEVDGRANTLLLRYQGVDGKQHTVSFRNLPLADGQWHKLALSVSGSSATLYVDCNEIDSRPLDRPGqpPIDTDG 157
                           170       180
                    ....*....|....*....|....*..
gi 767902478    205 HVFLGLDAEQGKPVSFDLQQVHIYCDP 231
Cdd:smart00210  158 IEVRGAQAADRKPFQGDLQQLKIVCDP 184
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
512-802 5.31e-19

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 91.12  E-value: 5.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  512 TLPEGFQNFVGlpgkPGPKGEPGdPVPARGDPGIQGIKGEKGEPclscssvvgaqhlvsstgasgdvgspgfGLPGLPGR 591
Cdd:NF038329  105 ELDEGLQQLKG----DGEKGEPG-PAGPAGPAGEQGPRGDRGET----------------------------GPAGPAGP 151
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  592 AGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGK 671
Cdd:NF038329  152 PGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG 231
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  672 QGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDgctacpslqgtvTDMAGRPGQPGPKGEQG 751
Cdd:NF038329  232 DGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGP------------VGPAGKDGQNGKDGLPG 299
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767902478  752 PEgvGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLP 802
Cdd:NF038329  300 KD--GKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKTPEVP 348
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
739-875 2.09e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 83.03  E-value: 2.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  739 GRPGQPGPKGEQGPEG-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPpgrgvQGPQGEPGAPGLPGIQGLPGPRGPPGPT 817
Cdd:NF038329  117 GEKGEPGPAGPAGPAGeQGPRGDRGETGPAGPAGPPGPQGERGEKGP-----AGPQGEAGPQGPAGKDGEAGAKGPAGEK 191
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767902478  818 GEKGAQGSPGVKGATGPVGPPGASVS---------------------GPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGE 875
Cdd:NF038329  192 GPQGPRGETGPAGEQGPAGPAGPDGEagpagedgpagpagdgqqgpdGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGP 270
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
337-605 4.61e-15

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 78.79  E-value: 4.61e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  337 GGKGERGLPGPPGSKGEKGARGNDcvrispdaplqcaeGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKP 416
Cdd:NF038329  117 GEKGEPGPAGPAGPAGEQGPRGDR--------------GETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEA 182
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  417 GRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGppglpgppgiglpgtpgdpggppgpkgdkgssgiPGKEGPGGKPGK 496
Cdd:NF038329  183 GAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDG----------------------------------EAGPAGEDGPAG 228
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  497 PGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPArGDPGIQGIKGEKGEPCLSCSSvvGAQHLVSSTGASG 576
Cdd:NF038329  229 PAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPD-GPDGKDGERGPVGPAGKDGQN--GKDGLPGKDGKDG 305
                         250       260
                  ....*....|....*....|....*....
gi 767902478  577 DVGSPgfGLPGLPGRAGVPGLKGEKGNFG 605
Cdd:NF038329  306 QNGKD--GLPGKDGKDGQPGKDGLPGKDG 332
 
Name Accession Description Interval E-value
TSPN smart00210
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of ...
50-231 5.08e-59

Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of thrombospondin


Pssm-ID: 214560  Cd Length: 184  Bit Score: 200.66  E-value: 5.08e-59
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478     50 GFNLIHRLSLM-KTSAIKKIRNPKGP-LILRLG-AAPVTQPTRRVFPRGLPEEFALVLTLLLKKhthQKTWYLFQVTDAN 126
Cdd:smart00210    1 GQDLLQVFDLPsLSFAIRQVVGPEPGsPAYRLGdPALVPQPTRDLFPSGLPEDFSLLTTFRQTP---KSRGVLFAIYDAQ 77
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478    127 GYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRR--PMRPVG 204
Cdd:smart00210   78 NVRQFGLEVDGRANTLLLRYQGVDGKQHTVSFRNLPLADGQWHKLALSVSGSSATLYVDCNEIDSRPLDRPGqpPIDTDG 157
                           170       180
                    ....*....|....*....|....*..
gi 767902478    205 HVFLGLDAEQGKPVSFDLQQVHIYCDP 231
Cdd:smart00210  158 IEVRGAQAADRKPFQGDLQQLKIVCDP 184
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
512-802 5.31e-19

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 91.12  E-value: 5.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  512 TLPEGFQNFVGlpgkPGPKGEPGdPVPARGDPGIQGIKGEKGEPclscssvvgaqhlvsstgasgdvgspgfGLPGLPGR 591
Cdd:NF038329  105 ELDEGLQQLKG----DGEKGEPG-PAGPAGPAGEQGPRGDRGET----------------------------GPAGPAGP 151
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  592 AGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGK 671
Cdd:NF038329  152 PGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG 231
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  672 QGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDgctacpslqgtvTDMAGRPGQPGPKGEQG 751
Cdd:NF038329  232 DGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGP------------VGPAGKDGQNGKDGLPG 299
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767902478  752 PEgvGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLP 802
Cdd:NF038329  300 KD--GKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKTPEVP 348
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
739-875 2.09e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 83.03  E-value: 2.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  739 GRPGQPGPKGEQGPEG-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPpgrgvQGPQGEPGAPGLPGIQGLPGPRGPPGPT 817
Cdd:NF038329  117 GEKGEPGPAGPAGPAGeQGPRGDRGETGPAGPAGPPGPQGERGEKGP-----AGPQGEAGPQGPAGKDGEAGAKGPAGEK 191
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767902478  818 GEKGAQGSPGVKGATGPVGPPGASVS---------------------GPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGE 875
Cdd:NF038329  192 GPQGPRGETGPAGEQGPAGPAGPDGEagpagedgpagpagdgqqgpdGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGP 270
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
337-605 4.61e-15

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 78.79  E-value: 4.61e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  337 GGKGERGLPGPPGSKGEKGARGNDcvrispdaplqcaeGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKP 416
Cdd:NF038329  117 GEKGEPGPAGPAGPAGEQGPRGDR--------------GETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEA 182
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  417 GRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGppglpgppgiglpgtpgdpggppgpkgdkgssgiPGKEGPGGKPGK 496
Cdd:NF038329  183 GAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDG----------------------------------EAGPAGEDGPAG 228
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  497 PGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPArGDPGIQGIKGEKGEPCLSCSSvvGAQHLVSSTGASG 576
Cdd:NF038329  229 PAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPD-GPDGKDGERGPVGPAGKDGQN--GKDGLPGKDGKDG 305
                         250       260
                  ....*....|....*....|....*....
gi 767902478  577 DVGSPgfGLPGLPGRAGVPGLKGEKGNFG 605
Cdd:NF038329  306 QNGKD--GLPGKDGKDGQPGKDGLPGKDG 332
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
374-717 7.03e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.25  E-value: 7.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  374 EGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPgppg 453
Cdd:NF038329  116 DGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEK---- 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  454 lpgppgiglpgtpgdpggppgpkgdkgssgipgkegpggkpgkpgvkGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEP 533
Cdd:NF038329  192 -----------------------------------------------GPQGPRGETGPAGEQGPAGPAGPDGEAGPAGED 224
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  534 GDPVPA-RGDPGIQGIKGEKGEpclscssvvgaqhlvssTGASGDVgspgfglpGLPGRAGVPGLKGEKGNFGEagpags 612
Cdd:NF038329  225 GPAGPAgDGQQGPDGDPGPTGE-----------------DGPQGPD--------GPAGKDGPRGDRGEAGPDGP------ 273
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  613 pgppgpvgpagiKGAKGEPCEPCPALSNLQDGDvrvVALPGPSGekgepgppgfglpgKQGKAGERGLKGQKGDAGNPGD 692
Cdd:NF038329  274 ------------DGKDGERGPVGPAGKDGQNGK---DGLPGKDG--------------KDGQNGKDGLPGKDGKDGQPGK 324
                         330       340
                  ....*....|....*....|....*
gi 767902478  693 PGTPGTTGRPGLSGEPGVQGPAGPK 717
Cdd:NF038329  325 DGLPGKDGKDGQPGKPAPKTPEVPQ 349
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
672-874 3.38e-07

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 54.27  E-value: 3.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  672 QGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKG---EKGDGCTACPSLQGTVTDMAGRPGQPGP-- 746
Cdd:COG5164    51 QGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQNQGGTRPAGNTGgttPAGDGGATGPPDDGGATGPPDDGGSTTPps 130
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  747 KGEQGPEGVG--RPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQG 824
Cdd:COG5164   131 GGSTTPPGDGgsTPPGPGSTGPGGSTTPPGDGGSTTPPGPGGSTTPPDDGGSTTPPNKGETGTDIPTGGTPRQGPDGPVK 210
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 767902478  825 SPGVKGATGPvgppgasvsgPPGRDGQQGQTGLRGTPGEKGPRGEKGEPG 874
Cdd:COG5164   211 KDDKNGKGNP----------PDDRGGKTGPKDQRPKTNPIERRGPERPEA 250
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
738-1035 4.83e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 4.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  738 AGRPGQPGPKGEQGPEG-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPG 815
Cdd:NF038329  122 PGPAGPAGPAGEQGPRGdRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGpQGPAGKDGEAGAKGPAGEKGPQGPRGETG 201
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  816 PTGEKGAQGSPGVKGATGPVGPPGASvsGPPGrDGQQGQTGLRGTPGEKGPRGEKGEPGEcscpsqgdlifsgmpgapgl 895
Cdd:NF038329  202 PAGEQGPAGPAGPDGEAGPAGEDGPA--GPAG-DGQQGPDGDPGPTGEDGPQGPDGPAGK-------------------- 258
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  896 wmgsswqpgpqgppgipgppgppgvpglqgvPGNNGLPGQPGLtaelgslpieqhllksicgdcvQGQRahpgylvekGE 975
Cdd:NF038329  259 -------------------------------DGPRGDRGEAGP----------------------DGPD---------GK 276
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  976 KGDQGIPGVPGldncaqcflslerpraeeargdnsegdpgcvgspglpgppgLPGQRGEE 1035
Cdd:NF038329  277 DGERGPVGPAG-----------------------------------------KDGQNGKD 295
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
742-803 3.43e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 45.18  E-value: 3.43e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767902478   742 GQPGPKGEQGPegvgrpgkPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPG 803
Cdd:pfam01391    1 GPPGPPGPPGP--------PGPPGPPGPPGPPGPPGPPGEPGPPGpPGPPGPPGPPGAPGAPG 55
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
295-423 1.38e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.75  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  295 GRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGndcvrispdaplqcae 374
Cdd:NF038329  233 GQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDG---------------- 296
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 767902478  375 gPKGEKGESGALGPSGLPGSTGEKGQKGEkgdggiKGVPGKPGRDGRPG 423
Cdd:NF038329  297 -LPGKDGKDGQNGKDGLPGKDGKDGQPGK------DGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
775-1034 2.20e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.90  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  775 LKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGasvsgPPGRDGQQGQ 854
Cdd:NF038329  107 DEGLQQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAG-----PQGPAGKDGE 181
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  855 TGLRGTPGEKGPRGEKGEPGEcscpsqgdlifSGMPGAPGLwmgsswqpgpqgppgipgppgppgvpglqgvPGNNGLPG 934
Cdd:NF038329  182 AGAKGPAGEKGPQGPRGETGP-----------AGEQGPAGP-------------------------------AGPDGEAG 219
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  935 QPGLTAELGSlpieqhllksiCGDCVQGQRAHPGylvEKGEKGDQGIPGVPGLDncaqcflslerpraeeargdnsegdp 1014
Cdd:NF038329  220 PAGEDGPAGP-----------AGDGQQGPDGDPG---PTGEDGPQGPDGPAGKD-------------------------- 259
                         250       260
                  ....*....|....*....|
gi 767902478 1015 gcvgspglpgppglpGQRGE 1034
Cdd:NF038329  260 ---------------GPRGD 264
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
747-936 3.34e-04

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 44.64  E-value: 3.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  747 KGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGrgvqgPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSP 826
Cdd:COG5164     1 TGLYGPGKTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAG-----NTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  827 GVKGATGPVGPPGASV-SGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGP 905
Cdd:COG5164    76 QNQGGTTPAQNQGGTRpAGNTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGGS 155
                         170       180       190
                  ....*....|....*....|....*....|.
gi 767902478  906 QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQP 936
Cdd:COG5164   156 TTPPGDGGSTTPPGPGGSTTPPDDGGSTTPP 186
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
706-881 6.01e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 6.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  706 GEPGVQGPAGPKGEKGDGCTACPSlqgtvtdmagRPGQPGPKGeqGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPP 785
Cdd:PRK07764  590 PAPGAAGGEGPPAPASSGPPEEAA----------RPAAPAAPA--APAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHV 657
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  786 GRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKG 865
Cdd:PRK07764  658 AVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD 737
                         170
                  ....*....|....*.
gi 767902478  866 PRGEKGEPGECSCPSQ 881
Cdd:PRK07764  738 PVPLPPEPDDPPDPAG 753
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
378-433 1.89e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.47  E-value: 1.89e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767902478   378 GEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQ 433
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
819-869 3.34e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 36.70  E-value: 3.34e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 767902478   819 EKGAQGSPGVKGATGPVGPPGAS-VSGPPGRDGQQGQTGLRGTPGEKGPRGE 869
Cdd:pfam01391    5 PPGPPGPPGPPGPPGPPGPPGPPgPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
 
Name Accession Description Interval E-value
TSPN smart00210
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of ...
50-231 5.08e-59

Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of thrombospondin


Pssm-ID: 214560  Cd Length: 184  Bit Score: 200.66  E-value: 5.08e-59
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478     50 GFNLIHRLSLM-KTSAIKKIRNPKGP-LILRLG-AAPVTQPTRRVFPRGLPEEFALVLTLLLKKhthQKTWYLFQVTDAN 126
Cdd:smart00210    1 GQDLLQVFDLPsLSFAIRQVVGPEPGsPAYRLGdPALVPQPTRDLFPSGLPEDFSLLTTFRQTP---KSRGVLFAIYDAQ 77
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478    127 GYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRR--PMRPVG 204
Cdd:smart00210   78 NVRQFGLEVDGRANTLLLRYQGVDGKQHTVSFRNLPLADGQWHKLALSVSGSSATLYVDCNEIDSRPLDRPGqpPIDTDG 157
                           170       180
                    ....*....|....*....|....*..
gi 767902478    205 HVFLGLDAEQGKPVSFDLQQVHIYCDP 231
Cdd:smart00210  158 IEVRGAQAADRKPFQGDLQQLKIVCDP 184
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
512-802 5.31e-19

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 91.12  E-value: 5.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  512 TLPEGFQNFVGlpgkPGPKGEPGdPVPARGDPGIQGIKGEKGEPclscssvvgaqhlvsstgasgdvgspgfGLPGLPGR 591
Cdd:NF038329  105 ELDEGLQQLKG----DGEKGEPG-PAGPAGPAGEQGPRGDRGET----------------------------GPAGPAGP 151
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  592 AGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGK 671
Cdd:NF038329  152 PGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAG 231
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  672 QGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDgctacpslqgtvTDMAGRPGQPGPKGEQG 751
Cdd:NF038329  232 DGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGP------------VGPAGKDGQNGKDGLPG 299
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767902478  752 PEgvGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLP 802
Cdd:NF038329  300 KD--GKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKTPEVP 348
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
739-875 2.09e-16

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 83.03  E-value: 2.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  739 GRPGQPGPKGEQGPEG-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPpgrgvQGPQGEPGAPGLPGIQGLPGPRGPPGPT 817
Cdd:NF038329  117 GEKGEPGPAGPAGPAGeQGPRGDRGETGPAGPAGPPGPQGERGEKGP-----AGPQGEAGPQGPAGKDGEAGAKGPAGEK 191
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767902478  818 GEKGAQGSPGVKGATGPVGPPGASVS---------------------GPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGE 875
Cdd:NF038329  192 GPQGPRGETGPAGEQGPAGPAGPDGEagpagedgpagpagdgqqgpdGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGP 270
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
337-605 4.61e-15

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 78.79  E-value: 4.61e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  337 GGKGERGLPGPPGSKGEKGARGNDcvrispdaplqcaeGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKP 416
Cdd:NF038329  117 GEKGEPGPAGPAGPAGEQGPRGDR--------------GETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEA 182
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  417 GRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGppglpgppgiglpgtpgdpggppgpkgdkgssgiPGKEGPGGKPGK 496
Cdd:NF038329  183 GAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDG----------------------------------EAGPAGEDGPAG 228
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  497 PGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPArGDPGIQGIKGEKGEPCLSCSSvvGAQHLVSSTGASG 576
Cdd:NF038329  229 PAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPD-GPDGKDGERGPVGPAGKDGQN--GKDGLPGKDGKDG 305
                         250       260
                  ....*....|....*....|....*....
gi 767902478  577 DVGSPgfGLPGLPGRAGVPGLKGEKGNFG 605
Cdd:NF038329  306 QNGKD--GLPGKDGKDGQPGKDGLPGKDG 332
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
374-717 7.03e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.25  E-value: 7.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  374 EGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPgppg 453
Cdd:NF038329  116 DGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEK---- 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  454 lpgppgiglpgtpgdpggppgpkgdkgssgipgkegpggkpgkpgvkGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEP 533
Cdd:NF038329  192 -----------------------------------------------GPQGPRGETGPAGEQGPAGPAGPDGEAGPAGED 224
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  534 GDPVPA-RGDPGIQGIKGEKGEpclscssvvgaqhlvssTGASGDVgspgfglpGLPGRAGVPGLKGEKGNFGEagpags 612
Cdd:NF038329  225 GPAGPAgDGQQGPDGDPGPTGE-----------------DGPQGPD--------GPAGKDGPRGDRGEAGPDGP------ 273
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  613 pgppgpvgpagiKGAKGEPCEPCPALSNLQDGDvrvVALPGPSGekgepgppgfglpgKQGKAGERGLKGQKGDAGNPGD 692
Cdd:NF038329  274 ------------DGKDGERGPVGPAGKDGQNGK---DGLPGKDG--------------KDGQNGKDGLPGKDGKDGQPGK 324
                         330       340
                  ....*....|....*....|....*
gi 767902478  693 PGTPGTTGRPGLSGEPGVQGPAGPK 717
Cdd:NF038329  325 DGLPGKDGKDGQPGKPAPKTPEVPQ 349
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
672-874 3.38e-07

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 54.27  E-value: 3.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  672 QGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKG---EKGDGCTACPSLQGTVTDMAGRPGQPGP-- 746
Cdd:COG5164    51 QGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQNQGGTRPAGNTGgttPAGDGGATGPPDDGGATGPPDDGGSTTPps 130
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  747 KGEQGPEGVG--RPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQG 824
Cdd:COG5164   131 GGSTTPPGDGgsTPPGPGSTGPGGSTTPPGDGGSTTPPGPGGSTTPPDDGGSTTPPNKGETGTDIPTGGTPRQGPDGPVK 210
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 767902478  825 SPGVKGATGPvgppgasvsgPPGRDGQQGQTGLRGTPGEKGPRGEKGEPG 874
Cdd:COG5164   211 KDDKNGKGNP----------PDDRGGKTGPKDQRPKTNPIERRGPERPEA 250
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
738-1035 4.83e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 4.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  738 AGRPGQPGPKGEQGPEG-VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPG 815
Cdd:NF038329  122 PGPAGPAGPAGEQGPRGdRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGpQGPAGKDGEAGAKGPAGEKGPQGPRGETG 201
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  816 PTGEKGAQGSPGVKGATGPVGPPGASvsGPPGrDGQQGQTGLRGTPGEKGPRGEKGEPGEcscpsqgdlifsgmpgapgl 895
Cdd:NF038329  202 PAGEQGPAGPAGPDGEAGPAGEDGPA--GPAG-DGQQGPDGDPGPTGEDGPQGPDGPAGK-------------------- 258
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  896 wmgsswqpgpqgppgipgppgppgvpglqgvPGNNGLPGQPGLtaelgslpieqhllksicgdcvQGQRahpgylvekGE 975
Cdd:NF038329  259 -------------------------------DGPRGDRGEAGP----------------------DGPD---------GK 276
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  976 KGDQGIPGVPGldncaqcflslerpraeeargdnsegdpgcvgspglpgppgLPGQRGEE 1035
Cdd:NF038329  277 DGERGPVGPAG-----------------------------------------KDGQNGKD 295
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
742-803 3.43e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 45.18  E-value: 3.43e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767902478   742 GQPGPKGEQGPegvgrpgkPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGLPG 803
Cdd:pfam01391    1 GPPGPPGPPGP--------PGPPGPPGPPGPPGPPGPPGEPGPPGpPGPPGPPGPPGAPGAPG 55
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
295-423 1.38e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.75  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  295 GRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGndcvrispdaplqcae 374
Cdd:NF038329  233 GQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDG---------------- 296
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 767902478  375 gPKGEKGESGALGPSGLPGSTGEKGQKGEkgdggiKGVPGKPGRDGRPG 423
Cdd:NF038329  297 -LPGKDGKDGQNGKDGLPGKDGKDGQPGK------DGLPGKDGKDGQPG 338
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
687-874 5.88e-05

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 47.31  E-value: 5.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478   687 AGNPGDPGTPGTTGRPGLSGEPGVQGPAGPK------GEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVgrPGK 760
Cdd:pfam09606  111 GQQMGGPGTASNLLASLGRPQMPMGGAGFPSqmsrvgRMQPGGQAGGMMQPSSGQPGSGTPNQMGPNGGPGQGQA--GGM 188
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478   761 PGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATG------P 834
Cdd:pfam09606  189 NGGQQGPMGGQMPPQMGVPGMPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGInqmqqmP 268
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 767902478   835 VGPPGASVSGPPGRDGQQGQTGlrgtPGEKGPRGEKGEPG 874
Cdd:pfam09606  269 QGVGGGAGQGGPGQPMGPPGQQ----PGAMPNVMSIGDQN 304
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
775-1034 2.20e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.90  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  775 LKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGasvsgPPGRDGQQGQ 854
Cdd:NF038329  107 DEGLQQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAG-----PQGPAGKDGE 181
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  855 TGLRGTPGEKGPRGEKGEPGEcscpsqgdlifSGMPGAPGLwmgsswqpgpqgppgipgppgppgvpglqgvPGNNGLPG 934
Cdd:NF038329  182 AGAKGPAGEKGPQGPRGETGP-----------AGEQGPAGP-------------------------------AGPDGEAG 219
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  935 QPGLTAELGSlpieqhllksiCGDCVQGQRAHPGylvEKGEKGDQGIPGVPGLDncaqcflslerpraeeargdnsegdp 1014
Cdd:NF038329  220 PAGEDGPAGP-----------AGDGQQGPDGDPG---PTGEDGPQGPDGPAGKD-------------------------- 259
                         250       260
                  ....*....|....*....|
gi 767902478 1015 gcvgspglpgppglpGQRGE 1034
Cdd:NF038329  260 ---------------GPRGD 264
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
747-936 3.34e-04

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 44.64  E-value: 3.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  747 KGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGrgvqgPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSP 826
Cdd:COG5164     1 TGLYGPGKTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAG-----NTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  827 GVKGATGPVGPPGASV-SGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGP 905
Cdd:COG5164    76 QNQGGTTPAQNQGGTRpAGNTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGGS 155
                         170       180       190
                  ....*....|....*....|....*....|.
gi 767902478  906 QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQP 936
Cdd:COG5164   156 TTPPGDGGSTTPPGPGGSTTPPDDGGSTTPP 186
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
706-881 6.01e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 6.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  706 GEPGVQGPAGPKGEKGDGCTACPSlqgtvtdmagRPGQPGPKGeqGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPP 785
Cdd:PRK07764  590 PAPGAAGGEGPPAPASSGPPEEAA----------RPAAPAAPA--APAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHV 657
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  786 GRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKG 865
Cdd:PRK07764  658 AVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD 737
                         170
                  ....*....|....*.
gi 767902478  866 PRGEKGEPGECSCPSQ 881
Cdd:PRK07764  738 PVPLPPEPDDPPDPAG 753
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
644-849 1.60e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  644 GDVRVVALPGP-SGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGD 722
Cdd:PRK07764  580 GDWQVEAVVGPaPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAV 659
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  723 gctacPSLQGTVTDMAGRPGQPGPKG-EQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGL 801
Cdd:PRK07764  660 -----PDASDGGDGWPAKAGGAAPAApPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPA 734
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 767902478  802 PGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRD 849
Cdd:PRK07764  735 ADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEE 782
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
378-433 1.89e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.47  E-value: 1.89e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767902478   378 GEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQ 433
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
PHA03169 PHA03169
hypothetical protein; Provisional
698-877 2.26e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 41.88  E-value: 2.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  698 TTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKG 777
Cdd:PHA03169   77 EESRHGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHN 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  778 vqGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGL 857
Cdd:PHA03169  157 --PSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHE 234
                         170       180
                  ....*....|....*....|
gi 767902478  858 RGTPGEKGPRGEKGEPGECS 877
Cdd:PHA03169  235 DEPTEPEREGPPFPGHRSHS 254
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
819-869 3.34e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 36.70  E-value: 3.34e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 767902478   819 EKGAQGSPGVKGATGPVGPPGAS-VSGPPGRDGQQGQTGLRGTPGEKGPRGE 869
Cdd:pfam01391    5 PPGPPGPPGPPGPPGPPGPPGPPgPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
375-424 3.58e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 36.70  E-value: 3.58e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 767902478   375 GPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGE 424
Cdd:pfam01391    4 GPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGA 53
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
334-403 7.87e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 35.55  E-value: 7.87e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478   334 GPKGGKGERGLPGPPGSKGEKGARGNDcvrispdaplqcaeGPKGEKGESGALGPSGLPGSTGEKGQKGE 403
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPP--------------GPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
687-875 9.35e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 9.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  687 AGNPGDPGTPGTTGRPGLSGEP-GVQGPAGPKGEKGDGCTACPSLQGTvtdmAGRPGQPGPKGEQGPEGVGRPGKPGQPG 765
Cdd:PRK07764  594 AAGGEGPPAPASSGPPEEAARPaAPAAPAAPAAPAPAGAAAAPAEASA----APAPGVAAPEHHPKHVAVPDASDGGDGW 669
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767902478  766 LPGVQGPPGLK---GVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGP--PGPTGEKGAQGSPGVKGATGPVGPPGA 840
Cdd:PRK07764  670 PAKAGGAAPAApppAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQppQAAQGASAPSPAADDPVPLPPEPDDPP 749
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767902478  841 SVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGE 875
Cdd:PRK07764  750 DPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEE 784
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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