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Conserved domains on  [gi|767903353|ref|XP_011539393|]
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calmodulin-binding transcription activator 1 isoform X16 [Homo sapiens]

Protein Classification

calmodulin-binding transcription activator( domain architecture ID 10660838)

calmodulin-binding transcription activator may act as a tumor suppressor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CG-1 smart01076
CG-1 domains are highly conserved domains of about 130 amino-acid residues; The domains ...
 67-183 2.85e-75

CG-1 domains are highly conserved domains of about 130 amino-acid residues; The domains contain a predicted bipartite NLS and are named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein. CG-1 domains are associated with CAMTA proteins (for CAlModulin -binding Transcription Activator) that are transcription factors containing a calmodulin -binding domain and ankyrins (ANK) motifs.


:

Pssm-ID: 198144  Cd Length: 118  Bit Score: 242.31  E-value: 2.85e-75
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767903353    67 LPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKY-RKDGYCWKKRKDGKTTREDHMKLKVQGV 145
Cdd:smart01076   1 LPEAKHRWLTPEEIAAILINFDKHTEWLTTSPPTRPKSGSLFLFNRKKLKYfRKDGYNWKKKKDGKTVREDHEKLKVGGI 80

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 767903353   146 ECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYLNVP 183
Cdd:smart01076  81 ECLHCYYAHSEINPTFHRRCYWLLQNPDIVLVHYLNVP 118
TIG pfam01833
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
 873-952 1.74e-08

IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.


:

Pssm-ID: 460355 [Multi-domain]  Cd Length: 84  Bit Score: 52.45  E-value: 1.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767903353  873 VTDYSPEWSYPEGGVKVLITGP-WQEASNNYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNN-QIISNSVVF 950
Cdd:pfam01833   3 ITSISPSSGPASGGTTITITGSnFGTDSSDLKVTIGGTPCTVISVSSTTIVCTTPPGTSGLVNVSVTVGGgGISSSPLTF 82


                  ..
gi 767903353  951 EY 952
Cdd:pfam01833  83 TY 84
 
Name Accession Description Interval E-value
CG-1 smart01076
CG-1 domains are highly conserved domains of about 130 amino-acid residues; The domains ...
 67-183 2.85e-75

CG-1 domains are highly conserved domains of about 130 amino-acid residues; The domains contain a predicted bipartite NLS and are named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein. CG-1 domains are associated with CAMTA proteins (for CAlModulin -binding Transcription Activator) that are transcription factors containing a calmodulin -binding domain and ankyrins (ANK) motifs.


Pssm-ID: 198144  Cd Length: 118  Bit Score: 242.31  E-value: 2.85e-75
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767903353    67 LPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKY-RKDGYCWKKRKDGKTTREDHMKLKVQGV 145
Cdd:smart01076   1 LPEAKHRWLTPEEIAAILINFDKHTEWLTTSPPTRPKSGSLFLFNRKKLKYfRKDGYNWKKKKDGKTVREDHEKLKVGGI 80

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 767903353   146 ECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYLNVP 183
Cdd:smart01076  81 ECLHCYYAHSEINPTFHRRCYWLLQNPDIVLVHYLNVP 118
CG-1 pfam03859
CG-1 domain; CG-1 domains are highly conserved domains of about 130 amino-acid residues ...
 71-182 1.34e-57

CG-1 domain; CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein. CG-1 domains are associated with CAMTA proteins (for CAlModulin -binding Transcription Activator) that are transcription factors containing a calmodulin -binding domain and ankyrins (ANK) motifs.


Pssm-ID: 461077  Cd Length: 114  Bit Score: 193.25  E-value: 1.34e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767903353   71 RHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKY-RKDGYCWKKRKDGKTTREDHMKLKVQGVECLY 149
Cdd:pfam03859   1 KTRWLKPQEILAILLNYDPYGFCITPEPPPRPPSGSLFLFDRKKLRYfRKDGHNWRKKKDGKTVREDHEKLKVGGVEAIH 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767903353  150 GCYVHSSIIPTFHRRCYWLLQNP-DIVLVHYLNV 182
Cdd:pfam03859  81 CYYAHSEDNPTFQRRIYWLLDSDyHIVLVHYLNV 114
TIG pfam01833
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
 873-952 1.74e-08

IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.


Pssm-ID: 460355 [Multi-domain]  Cd Length: 84  Bit Score: 52.45  E-value: 1.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767903353  873 VTDYSPEWSYPEGGVKVLITGP-WQEASNNYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNN-QIISNSVVF 950
Cdd:pfam01833   3 ITSISPSSGPASGGTTITITGSnFGTDSSDLKVTIGGTPCTVISVSSTTIVCTTPPGTSGLVNVSVTVGGgGISSSPLTF 82


                  ..
gi 767903353  951 EY 952
Cdd:pfam01833  83 TY 84
 
Name Accession Description Interval E-value
CG-1 smart01076
CG-1 domains are highly conserved domains of about 130 amino-acid residues; The domains ...
 67-183 2.85e-75

CG-1 domains are highly conserved domains of about 130 amino-acid residues; The domains contain a predicted bipartite NLS and are named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein. CG-1 domains are associated with CAMTA proteins (for CAlModulin -binding Transcription Activator) that are transcription factors containing a calmodulin -binding domain and ankyrins (ANK) motifs.


Pssm-ID: 198144  Cd Length: 118  Bit Score: 242.31  E-value: 2.85e-75
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767903353    67 LPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKY-RKDGYCWKKRKDGKTTREDHMKLKVQGV 145
Cdd:smart01076   1 LPEAKHRWLTPEEIAAILINFDKHTEWLTTSPPTRPKSGSLFLFNRKKLKYfRKDGYNWKKKKDGKTVREDHEKLKVGGI 80

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 767903353   146 ECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYLNVP 183
Cdd:smart01076  81 ECLHCYYAHSEINPTFHRRCYWLLQNPDIVLVHYLNVP 118
CG-1 pfam03859
CG-1 domain; CG-1 domains are highly conserved domains of about 130 amino-acid residues ...
 71-182 1.34e-57

CG-1 domain; CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein. CG-1 domains are associated with CAMTA proteins (for CAlModulin -binding Transcription Activator) that are transcription factors containing a calmodulin -binding domain and ankyrins (ANK) motifs.


Pssm-ID: 461077  Cd Length: 114  Bit Score: 193.25  E-value: 1.34e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767903353   71 RHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKY-RKDGYCWKKRKDGKTTREDHMKLKVQGVECLY 149
Cdd:pfam03859   1 KTRWLKPQEILAILLNYDPYGFCITPEPPPRPPSGSLFLFDRKKLRYfRKDGHNWRKKKDGKTVREDHEKLKVGGVEAIH 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767903353  150 GCYVHSSIIPTFHRRCYWLLQNP-DIVLVHYLNV 182
Cdd:pfam03859  81 CYYAHSEDNPTFQRRIYWLLDSDyHIVLVHYLNV 114
TIG pfam01833
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
 873-952 1.74e-08

IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.


Pssm-ID: 460355 [Multi-domain]  Cd Length: 84  Bit Score: 52.45  E-value: 1.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767903353  873 VTDYSPEWSYPEGGVKVLITGP-WQEASNNYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNN-QIISNSVVF 950
Cdd:pfam01833   3 ITSISPSSGPASGGTTITITGSnFGTDSSDLKVTIGGTPCTVISVSSTTIVCTTPPGTSGLVNVSVTVGGgGISSSPLTF 82


                  ..
gi 767903353  951 EY 952
Cdd:pfam01833  83 TY 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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