peroxisomal membrane protein PEX14 isoform X4 [Homo sapiens]
Protein Classification
peroxisomal membrane protein PEX14( domain architecture ID 6533)
peroxisomal membrane protein PEX14 is a receptor-docking protein which is located on the cytoplasmic surface of the peroxisomal membrane and binds peroxisomal targeting signal (PTS) receptors carrying proteins bound for the peroxisomal matrix.
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Pex14_N super family | cl04682 | Pex14 N-terminal domain; Family of peroxisomal membrane anchor proteins which bind the PTS1 ... |
24-57 | 6.66e-09 | ||
Pex14 N-terminal domain; Family of peroxisomal membrane anchor proteins which bind the PTS1 (peroxisomal targeting signal) receptor and are required for the import of PTS1-containing proteins into peroxisomes. Loss of functional Pex14p results in defects in both the PTS1 and PTS2-dependent import pathways. Deletion analysis of this conserved region implicates it in selective peroxisome degradation. In the majority of members this region is situated at the N-terminus of the protein. The actual alignment was detected with superfamily member pfam04695: Pssm-ID: 461395 [Multi-domain] Cd Length: 46 Bit Score: 51.02 E-value: 6.66e-09
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| Name | Accession | Description | Interval | E-value | ||
| Pex14_N | pfam04695 | Pex14 N-terminal domain; Family of peroxisomal membrane anchor proteins which bind the PTS1 ... |
24-57 | 6.66e-09 | ||
Pex14 N-terminal domain; Family of peroxisomal membrane anchor proteins which bind the PTS1 (peroxisomal targeting signal) receptor and are required for the import of PTS1-containing proteins into peroxisomes. Loss of functional Pex14p results in defects in both the PTS1 and PTS2-dependent import pathways. Deletion analysis of this conserved region implicates it in selective peroxisome degradation. In the majority of members this region is situated at the N-terminus of the protein. Pssm-ID: 461395 [Multi-domain] Cd Length: 46 Bit Score: 51.02 E-value: 6.66e-09
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| Name | Accession | Description | Interval | E-value | ||
| Pex14_N | pfam04695 | Pex14 N-terminal domain; Family of peroxisomal membrane anchor proteins which bind the PTS1 ... |
24-57 | 6.66e-09 | ||
Pex14 N-terminal domain; Family of peroxisomal membrane anchor proteins which bind the PTS1 (peroxisomal targeting signal) receptor and are required for the import of PTS1-containing proteins into peroxisomes. Loss of functional Pex14p results in defects in both the PTS1 and PTS2-dependent import pathways. Deletion analysis of this conserved region implicates it in selective peroxisome degradation. In the majority of members this region is situated at the N-terminus of the protein. Pssm-ID: 461395 [Multi-domain] Cd Length: 46 Bit Score: 51.02 E-value: 6.66e-09
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