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Conserved domains on  [gi|767970735|ref|XP_011541355|]
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centrosomal protein of 295 kDa isoform X16 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ALMS_motif super family cl21154
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
1980-2091 1.07e-06

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


The actual alignment was detected with superfamily member pfam15309:

Pssm-ID: 464634  Cd Length: 131  Bit Score: 49.68  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767970735  1980 SLQEAFIKRKKSFMERSHQRQKeiRNKIHVSE-------NSQIKTVKEKPSISSSVSRLKGVNKVRASFPEDRKTTQALR 2052
Cdd:pfam15309    5 SLQEALEMHRPDFISRSRERLK--RLELLVEErklqevlQRERERLFNKPIPRTNKRQQTVPLPDNLFKPRRRAISKKEM 82
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 767970735  2053 HQRGLRLYNQLAEVKQQKEEKTKQEAYAQNRARAKEFHK 2091
Cdd:pfam15309   83 IARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKK 121
 
Name Accession Description Interval E-value
ALMS_motif pfam15309
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
1980-2091 1.07e-06

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


Pssm-ID: 464634  Cd Length: 131  Bit Score: 49.68  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767970735  1980 SLQEAFIKRKKSFMERSHQRQKeiRNKIHVSE-------NSQIKTVKEKPSISSSVSRLKGVNKVRASFPEDRKTTQALR 2052
Cdd:pfam15309    5 SLQEALEMHRPDFISRSRERLK--RLELLVEErklqevlQRERERLFNKPIPRTNKRQQTVPLPDNLFKPRRRAISKKEM 82
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 767970735  2053 HQRGLRLYNQLAEVKQQKEEKTKQEAYAQNRARAKEFHK 2091
Cdd:pfam15309   83 IARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKK 121
 
Name Accession Description Interval E-value
ALMS_motif pfam15309
ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), ...
1980-2091 1.07e-06

ALMS motif; This domain is found at the C-terminus of Alstrom syndrome protein 1 (ALMS1), KIAA1731 and C10orf90.


Pssm-ID: 464634  Cd Length: 131  Bit Score: 49.68  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767970735  1980 SLQEAFIKRKKSFMERSHQRQKeiRNKIHVSE-------NSQIKTVKEKPSISSSVSRLKGVNKVRASFPEDRKTTQALR 2052
Cdd:pfam15309    5 SLQEALEMHRPDFISRSRERLK--RLELLVEErklqevlQRERERLFNKPIPRTNKRQQTVPLPDNLFKPRRRAISKKEM 82
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 767970735  2053 HQRGLRLYNQLAEVKQQKEEKTKQEAYAQNRARAKEFHK 2091
Cdd:pfam15309   83 IARSKRIYEQLPEVKKKKEEEKRKAEYKSNRLKAQLFKK 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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