lysosomal membrane ascorbate-dependent ferrireductase CYB561A3 isoform X1 [Homo sapiens]
cytochrome b family protein( domain architecture ID 10171794)
cytochrome b family protein such as formate dehydrogenase subunit gamma or cytochrome b, a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
Cyt_b561_CYBASC3 | cd08762 | Vertebrate cytochrome b(561), CYBASC3 gene product; Cytochrome b ascorbate-dependent 3, as ... |
36-205 | 3.11e-99 | ||||
Vertebrate cytochrome b(561), CYBASC3 gene product; Cytochrome b ascorbate-dependent 3, as found in vertebrates, which might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. : Pssm-ID: 176492 Cd Length: 179 Bit Score: 288.30 E-value: 3.11e-99
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Name | Accession | Description | Interval | E-value | ||||
Cyt_b561_CYBASC3 | cd08762 | Vertebrate cytochrome b(561), CYBASC3 gene product; Cytochrome b ascorbate-dependent 3, as ... |
36-205 | 3.11e-99 | ||||
Vertebrate cytochrome b(561), CYBASC3 gene product; Cytochrome b ascorbate-dependent 3, as found in vertebrates, which might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. Pssm-ID: 176492 Cd Length: 179 Bit Score: 288.30 E-value: 3.11e-99
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Cytochrom_B561 | pfam03188 | Eukaryotic cytochrome b561; Cytochrome b561 is a secretory vesicle-specific electron transport ... |
63-199 | 2.19e-49 | ||||
Eukaryotic cytochrome b561; Cytochrome b561 is a secretory vesicle-specific electron transport protein. It is an integral membrane protein, that binds two heme groups non-covalently. This is a eukaryotic family. Members of the 'prokaryotic cytochrome b561' family can be found in Pfam: PF01292. Pssm-ID: 427188 Cd Length: 137 Bit Score: 159.69 E-value: 2.19e-49
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PLN02680 | PLN02680 | carbon-monoxide oxygenase |
40-232 | 5.07e-38 | ||||
carbon-monoxide oxygenase Pssm-ID: 215365 Cd Length: 232 Bit Score: 133.77 E-value: 5.07e-38
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B561 | smart00665 | Cytochrome b-561 / ferric reductase transmembrane domain; Cytochrome b-561 recycles ascorbate ... |
63-192 | 3.61e-34 | ||||
Cytochrome b-561 / ferric reductase transmembrane domain; Cytochrome b-561 recycles ascorbate for the generation of norepinephrine by dopamine-beta-hydroxylase in the chromaffin vesicles of the adrenal gland. It is a transmembrane heme protein with the two heme groups being bound to conserved histidine residues. A cytochrome b-561 homologue, termed Dcytb, is an iron-regulated ferric reductase in the duodenal mucosa. Other homologues of these are also likely to be ferric reductases. SDR2 is proposed to be important in regulating the metabolism of iron in the onset of neurodegenerative disorders. Pssm-ID: 214769 Cd Length: 129 Bit Score: 120.41 E-value: 3.61e-34
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Name | Accession | Description | Interval | E-value | ||||
Cyt_b561_CYBASC3 | cd08762 | Vertebrate cytochrome b(561), CYBASC3 gene product; Cytochrome b ascorbate-dependent 3, as ... |
36-205 | 3.11e-99 | ||||
Vertebrate cytochrome b(561), CYBASC3 gene product; Cytochrome b ascorbate-dependent 3, as found in vertebrates, which might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. Pssm-ID: 176492 Cd Length: 179 Bit Score: 288.30 E-value: 3.11e-99
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Cyt_b561_CG1275_like | cd08764 | Non-vertebrate eumetazoan cytochrome b(561); Cytochrome b(561), as found in non-vertebrate ... |
38-256 | 2.48e-69 | ||||
Non-vertebrate eumetazoan cytochrome b(561); Cytochrome b(561), as found in non-vertebrate eumetazoans, similar to the Drosophila melanogaster CG1275 gene product. This protein might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. Pssm-ID: 176494 Cd Length: 214 Bit Score: 213.35 E-value: 2.48e-69
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Cytochrom_B561 | pfam03188 | Eukaryotic cytochrome b561; Cytochrome b561 is a secretory vesicle-specific electron transport ... |
63-199 | 2.19e-49 | ||||
Eukaryotic cytochrome b561; Cytochrome b561 is a secretory vesicle-specific electron transport protein. It is an integral membrane protein, that binds two heme groups non-covalently. This is a eukaryotic family. Members of the 'prokaryotic cytochrome b561' family can be found in Pfam: PF01292. Pssm-ID: 427188 Cd Length: 137 Bit Score: 159.69 E-value: 2.19e-49
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Cyt_b561_CYBRD1 | cd08765 | Vertebrate cytochrome b(561), CYBRD1 gene product; Duodenal cytochrome b or ferric-chelate ... |
51-202 | 7.05e-46 | ||||
Vertebrate cytochrome b(561), CYBRD1 gene product; Duodenal cytochrome b or ferric-chelate reductase 3, a cytochrome b(561), as found in vertebrates, which might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. This protein is expressed at the brush border of duodenal enterocytes and may play a role in the uptake of dietary Fe(3+), facilitating its transport into the mucosal cells. It may also be involved in the recycling of extracellular ascorbate in erythrocyte membranes, and act as a ferrireductase in epithelial cells of the respiratory system. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. Pssm-ID: 176495 Cd Length: 153 Bit Score: 151.59 E-value: 7.05e-46
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Cyt_b561 | cd08554 | Eukaryotic cytochrome b(561); Cytochrome b(561) is a family of endosomal or secretory ... |
60-192 | 2.85e-42 | ||||
Eukaryotic cytochrome b(561); Cytochrome b(561) is a family of endosomal or secretory vesicle-specific electron transport proteins. They are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. This is an exclusively eukaryotic family. Members of the prokaryotic cytochrome b561 family are not deemed homologous. Pssm-ID: 176489 Cd Length: 131 Bit Score: 141.27 E-value: 2.85e-42
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PLN02680 | PLN02680 | carbon-monoxide oxygenase |
40-232 | 5.07e-38 | ||||
carbon-monoxide oxygenase Pssm-ID: 215365 Cd Length: 232 Bit Score: 133.77 E-value: 5.07e-38
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Cyt_b561_ACYB-1_like | cd08766 | Plant cytochrome b(561), including the carbon monoxide oxygenase ACYB-1; Cytochrome b(561), as ... |
61-198 | 5.46e-37 | ||||
Plant cytochrome b(561), including the carbon monoxide oxygenase ACYB-1; Cytochrome b(561), as found in plants, similar to the Arabidopsis thaliana ACYB-1 gene product, a cytochrome b561 isoform localized to the tonoplast. This protein might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), and might be capable of trans-membrane electron transport from intracellular ascorbate to extracellular ferric chelates. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. Pssm-ID: 176496 Cd Length: 144 Bit Score: 128.19 E-value: 5.46e-37
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Cyt_b561_CYB561 | cd08763 | Vertebrate cytochrome b(561), CYB561 gene product; Cytochrome b(561), as found in vertebrates, ... |
54-198 | 5.71e-37 | ||||
Vertebrate cytochrome b(561), CYB561 gene product; Cytochrome b(561), as found in vertebrates, which might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. Pssm-ID: 176493 Cd Length: 143 Bit Score: 128.01 E-value: 5.71e-37
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B561 | smart00665 | Cytochrome b-561 / ferric reductase transmembrane domain; Cytochrome b-561 recycles ascorbate ... |
63-192 | 3.61e-34 | ||||
Cytochrome b-561 / ferric reductase transmembrane domain; Cytochrome b-561 recycles ascorbate for the generation of norepinephrine by dopamine-beta-hydroxylase in the chromaffin vesicles of the adrenal gland. It is a transmembrane heme protein with the two heme groups being bound to conserved histidine residues. A cytochrome b-561 homologue, termed Dcytb, is an iron-regulated ferric reductase in the duodenal mucosa. Other homologues of these are also likely to be ferric reductases. SDR2 is proposed to be important in regulating the metabolism of iron in the onset of neurodegenerative disorders. Pssm-ID: 214769 Cd Length: 129 Bit Score: 120.41 E-value: 3.61e-34
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PLN02810 | PLN02810 | carbon-monoxide oxygenase |
44-239 | 5.53e-31 | ||||
carbon-monoxide oxygenase Pssm-ID: 178406 Cd Length: 231 Bit Score: 115.30 E-value: 5.53e-31
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PLN02351 | PLN02351 | cytochromes b561 family protein |
64-238 | 5.40e-16 | ||||
cytochromes b561 family protein Pssm-ID: 215201 Cd Length: 242 Bit Score: 75.33 E-value: 5.40e-16
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Cyt_b561_FRRS1_like | cd08760 | Eukaryotic cytochrome b(561), including the FRRS1 gene product; Cytochrome b(561), as found in ... |
47-192 | 1.62e-11 | ||||
Eukaryotic cytochrome b(561), including the FRRS1 gene product; Cytochrome b(561), as found in eukaryotes, similar to and including the human FRRS1 gene product (ferric-chelate reductase 1), also called SDR-2 (stromal cell-derived receptor 2). This family comprises a variety of domain architectures, many of which contain dopamine beta-monooxygenase (DOMON) domains. The protein might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. Pssm-ID: 176490 Cd Length: 191 Bit Score: 61.98 E-value: 1.62e-11
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Cyt_b561_CYB561D2_like | cd08761 | Eukaryotic cytochrome b(561), including the CYB561D2 gene product; Cytochrome b(561), as found ... |
51-197 | 2.21e-09 | ||||
Eukaryotic cytochrome b(561), including the CYB561D2 gene product; Cytochrome b(561), as found in eukaryotes, similar to and including the human CYB561D2 gene product. CYB561D2 is a candidate tumor suppressor. The protein might act as a ferric-chelate reductase, catalyzing the reduction of Fe(3+) to Fe(2+), such as associated with the transport of iron from the endosome to the cytoplasm. It is assumed that this protein uses ascorbate as the electron donor. Belongs to the cytochrome b(561) family, which are secretory vesicle-specific electron transport proteins. Cytochromes b(561) are integral membrane proteins that bind two heme groups non-covalently, and may have six alpha-helical trans-membrane segments. Pssm-ID: 176491 Cd Length: 183 Bit Score: 55.76 E-value: 2.21e-09
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Blast search parameters | ||||
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