interleukin-4 receptor subunit alpha isoform X3 [Homo sapiens]
IL4Ra_N and FN3 domain-containing protein( domain architecture ID 10283511)
IL4Ra_N and FN3 domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||
IL4Ra_N super family | cl07754 | Interleukin-4 receptor alpha chain, N-terminal; Members of this family are related in overall ... |
1-32 | 3.35e-14 | |||
Interleukin-4 receptor alpha chain, N-terminal; Members of this family are related in overall topology to fibronectin type III modules and fold into a sandwich comprising seven antiparallel beta sheets arranged in a three-strand and a four-strand beta-pleated sheet. They are required for binding of interleukin-4 to the receptor alpha chain, which is a crucial event for the generation of a Th2-dominated early immune response. The actual alignment was detected with superfamily member pfam09238: Pssm-ID: 462720 Cd Length: 94 Bit Score: 68.55 E-value: 3.35e-14
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FN3 | cd00063 | Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
34-130 | 1.69e-06 | |||
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases. : Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 46.72 E-value: 1.69e-06
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Name | Accession | Description | Interval | E-value | |||
IL4Ra_N | pfam09238 | Interleukin-4 receptor alpha chain, N-terminal; Members of this family are related in overall ... |
1-32 | 3.35e-14 | |||
Interleukin-4 receptor alpha chain, N-terminal; Members of this family are related in overall topology to fibronectin type III modules and fold into a sandwich comprising seven antiparallel beta sheets arranged in a three-strand and a four-strand beta-pleated sheet. They are required for binding of interleukin-4 to the receptor alpha chain, which is a crucial event for the generation of a Th2-dominated early immune response. Pssm-ID: 462720 Cd Length: 94 Bit Score: 68.55 E-value: 3.35e-14
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FN3 | cd00063 | Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
34-130 | 1.69e-06 | |||
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases. Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 46.72 E-value: 1.69e-06
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FN3 | smart00060 | Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
34-114 | 1.01e-05 | |||
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins. Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.14 E-value: 1.01e-05
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fn3 | pfam00041 | Fibronectin type III domain; |
36-127 | 1.83e-03 | |||
Fibronectin type III domain; Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 37.78 E-value: 1.83e-03
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Name | Accession | Description | Interval | E-value | |||
IL4Ra_N | pfam09238 | Interleukin-4 receptor alpha chain, N-terminal; Members of this family are related in overall ... |
1-32 | 3.35e-14 | |||
Interleukin-4 receptor alpha chain, N-terminal; Members of this family are related in overall topology to fibronectin type III modules and fold into a sandwich comprising seven antiparallel beta sheets arranged in a three-strand and a four-strand beta-pleated sheet. They are required for binding of interleukin-4 to the receptor alpha chain, which is a crucial event for the generation of a Th2-dominated early immune response. Pssm-ID: 462720 Cd Length: 94 Bit Score: 68.55 E-value: 3.35e-14
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FN3 | cd00063 | Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
34-130 | 1.69e-06 | |||
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases. Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 46.72 E-value: 1.69e-06
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FN3 | smart00060 | Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
34-114 | 1.01e-05 | |||
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins. Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.14 E-value: 1.01e-05
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fn3 | pfam00041 | Fibronectin type III domain; |
36-127 | 1.83e-03 | |||
Fibronectin type III domain; Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 37.78 E-value: 1.83e-03
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Blast search parameters | ||||
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