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Conserved domains on  [gi|1034632653|ref|XP_016861678|]
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golgin subfamily B member 1 isoform X2 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1901-2773 2.36e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.36e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1901 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1970
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1971 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2043
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2044 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2120
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2121 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2198
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2199 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2276
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2277 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2353
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2354 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2425
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2426 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2505
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2506 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2585
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2586 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2665
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2666 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2741
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1034632653 2742 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2773
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1353-2180 2.47e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.47e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1353 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1432
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1433 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1509
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1510 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1589
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1590 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1669
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1670 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1749
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1750 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1829
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1830 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1903
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1904 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1983
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1984 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2062
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2063 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2142
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1034632653 2143 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2180
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 759-1533 6.62e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.62e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  759 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 838
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  839 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 918
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  919 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 998
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  999 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1077
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1078 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1143
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1144 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1199
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1200 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1250
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1251 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1325
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1326 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1395
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1396 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1463
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632653 1464 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1533
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1019 3.53e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 3.53e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  190 QQLQEKEEFISTLQAQLSQTQAEQAaqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLV 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL-----REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  270 GRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQF 349
Cdd:TIGR02168  288 KE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  350 EQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQ 429
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  430 KSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQIT 509
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  510 LLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEA 569
Cdd:TIGR02168  493 SLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNE 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  570 QEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTS 649
Cdd:TIGR02168  570 LGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  650 EEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQL 724
Cdd:TIGR02168  643 PGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  725 IEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIE 804
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEE 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  805 AKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLE 884
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  885 KKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ 961
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEV 936

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653  962 NYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1019
Cdd:TIGR02168  937 RIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2454-3187 2.09e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2454 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2523
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2524 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2597
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2598 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2660
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2661 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2724
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2725 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2796
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2797 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2876
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2877 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2956
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2957 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3036
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 3037 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3116
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632653 3117 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3187
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1901-2773 2.36e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.36e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1901 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1970
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1971 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2043
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2044 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2120
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2121 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2198
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2199 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2276
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2277 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2353
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2354 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2425
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2426 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2505
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2506 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2585
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2586 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2665
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2666 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2741
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1034632653 2742 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2773
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1353-2180 2.47e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.47e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1353 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1432
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1433 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1509
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1510 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1589
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1590 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1669
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1670 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1749
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1750 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1829
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1830 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1903
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1904 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1983
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1984 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2062
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2063 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2142
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1034632653 2143 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2180
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 759-1533 6.62e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.62e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  759 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 838
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  839 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 918
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  919 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 998
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  999 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1077
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1078 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1143
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1144 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1199
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1200 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1250
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1251 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1325
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1326 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1395
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1396 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1463
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632653 1464 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1533
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1019 3.53e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 3.53e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  190 QQLQEKEEFISTLQAQLSQTQAEQAaqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLV 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL-----REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  270 GRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQF 349
Cdd:TIGR02168  288 KE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  350 EQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQ 429
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  430 KSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQIT 509
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  510 LLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEA 569
Cdd:TIGR02168  493 SLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNE 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  570 QEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTS 649
Cdd:TIGR02168  570 LGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  650 EEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQL 724
Cdd:TIGR02168  643 PGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  725 IEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIE 804
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEE 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  805 AKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLE 884
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  885 KKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ 961
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEV 936

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653  962 NYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1019
Cdd:TIGR02168  937 RIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1834-2379 1.32e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.32e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1834 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1913
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1914 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1993
Cdd:COG1196    310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1994 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2073
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2074 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2149
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2150 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2229
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2230 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2302
Cdd:COG1196    629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653 2303 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2379
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1370-1937 2.13e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1370 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1449
Cdd:COG1196    218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1450 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1529
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1530 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1609
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1683
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1684 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1753
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1754 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1828
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1829 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1908
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1034632653 1909 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1937
Cdd:COG1196    773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2454-3187 2.09e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2454 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2523
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2524 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2597
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2598 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2660
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2661 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2724
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2725 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2796
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2797 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2876
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2877 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2956
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2957 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3036
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 3037 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3116
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632653 3117 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3187
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 759-1120 3.42e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  759 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 838
Cdd:COG1196    195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  839 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 918
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  919 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 998
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  999 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1078
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1034632653 1079 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1120
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1495-2088 1.54e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1495 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1571
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1572 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1642
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1643 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1722
Cdd:PRK03918   323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1723 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1797
Cdd:PRK03918   384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1798 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1876
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1877 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1956
Cdd:PRK03918   534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1957 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 2035
Cdd:PRK03918   603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 2036 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2088
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 635-1230 4.73e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 4.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  635 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 714
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  715 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 794
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  795 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 867
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  868 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 947
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  948 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 1003
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1004 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1080
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1081 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1160
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1161 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1230
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1839-2339 1.14e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.31  E-value: 1.14e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1839 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1918
Cdd:PRK03918   230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1919 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1992
Cdd:PRK03918   309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1993 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2060
Cdd:PRK03918   388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2061 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2140
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2141 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2210
Cdd:PRK03918   541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2211 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2290
Cdd:PRK03918   621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632653 2291 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2339
Cdd:PRK03918   662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1301-2179 5.03e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 5.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1301 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1380
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1381 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1460
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1461 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1540
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1541 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1620
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1621 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1700
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1701 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1780
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1781 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1860
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1861 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1939
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1940 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 2019
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2020 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2099
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2100 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2179
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2638-2941 9.13e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 9.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2638 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2709
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2710 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2782
Cdd:COG1196    260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2783 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2858
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2859 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2938
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                   ...
gi 1034632653 2939 RQE 2941
Cdd:COG1196    500 EAD 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-643 1.13e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 1.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653   48 EDVQERLAyaeqlvvELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:COG1196    182 EATEENLE-------RLEDILGELERQL----EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  208 QTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQ 287
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  288 RNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALE 367
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  368 QKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT----------IQQLEDQLQQKSKEISQF 437
Cdd:COG1196    491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAalaaalqnivVEDDEVAAAAIEYLKAAK 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  438 LNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRT 517
Cdd:COG1196    571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  518 GEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKE 597
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1034632653  598 MKQMEgegIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTE 643
Cdd:COG1196    731 EAERE---ELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
PTZ00121 PTZ00121
MAEBL; Provisional
 702-1229 2.70e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  702 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 779
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  780 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 852
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  853 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 928
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  929 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1008
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1009 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1088
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1089 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1168
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632653 1169 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1229
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1947-2688 8.46e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 8.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1947 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2026
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2027 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2106
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2107 SNKESVKSQMKQKDEdlerrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEnldstvtq 2186
Cdd:pfam02463  332 KEKEEIEELEKELKE-----LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-------- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2187 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES 2266
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2267 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2346
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2347 ADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIV 2426
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2427 LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRivgdyQQLEERHLSIILEKDQLIQEAAAENN 2506
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAES-----ELAKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2507 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDL 2586
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2587 RRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrLSALFSSSQKRIAELEEELVCVQ 2666
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK---LEKLAEEELERLEEEITKEELLQ 870

                          730       740
                   ....*....|....*....|..
gi 1034632653 2667 KEAAKKVGEIEDKLKKELKHLH 2688
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKE 892
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 155-425 5.44e-06

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 52.53  E-value: 5.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  155 EKEELISTLQAQLTQAQAEQPAQSSTEMEEfvMMKQQL-QEKEEF---ISTLQAQLSQTQAEQAAQQVVREKDArFETQV 230
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADKERAE--ADRQRLeQEKQQQlaaISGSQSQLESTDQNALETNGQAQRDA-ILEES 1615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  231 RLHEDELlqlvtqadveTEMQQKLRVLQRKLEEHEES-------LVGRaqVVDLLQQELTAAeqrNQILSQQL----QQM 299
Cdd:NF012221  1616 RAVTKEL----------TTLAQGLDALDSQATYAGESgdqwrnpFAGG--LLDRVQEQLDDA---KKISGKQLadakQRH 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  300 EAEHNTLRNTVetereeskillEKMELEVAErklSFHNLQEEmhhlleqfEQAG-QAQAELESRYS-ALEQKHKAEMEEK 377
Cdd:NF012221  1681 VDNQQKVKDAV-----------AKSEAGVAQ---GEQNQANA--------EQDIdDAKADAEKRKDdALAKQNEAQQAES 1738

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1034632653  378 TSHILSlqktgQELQSAcdalKDQNSKLLQDKNEQAVQSAQTIQQLED 425
Cdd:NF012221  1739 DANAAA-----NDAQSR----GEQDASAAENKANQAQADAKGAKQDES 1777
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1824-2062 5.66e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1824 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1903
Cdd:NF012221  1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1904 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1979
Cdd:NF012221  1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1980 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2051
Cdd:NF012221  1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|.
gi 1034632653 2052 SQKDLEITKEN 2062
Cdd:NF012221  1765 AQADAKGAKQD 1775
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 172-1048 3.35e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 3.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  172 AEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQ 251
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  252 QKLRVLQRKLEEHEESL-VGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAE 330
Cdd:pfam02463  262 KEEEKLAQVLKENKEEEkEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  331 RKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKT--GQELQSACDALKDQNSKLLQD 408
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElkSEEEKEAQLLLELARQLEDLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  409 KNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEgtqaVTEENIASLQKRVVELENEKGALL 488
Cdd:pfam02463  422 KEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL----LKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  489 LSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKE 568
Cdd:pfam02463  498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  569 AQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQmegeGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRT 648
Cdd:pfam02463  578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLD----KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVS 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  649 SEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEF 728
Cdd:pfam02463  654 LEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  729 KKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSK 808
Cdd:pfam02463  734 INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  809 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRD 888
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  889 VETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSP 968
Cdd:pfam02463  894 KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  969 AG------QISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE 1042
Cdd:pfam02463  974 KVnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAELRLEDP 1053


                   ....*.
gi 1034632653 1043 NKEYSE 1048
Cdd:pfam02463 1054 DDPFSG 1059
mukB PRK04863
chromosome partition protein MukB;
234-436 4.84e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 4.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  234 EDELLQLVTQADVETE----MQQKLRVLQRKLEEHEESL---------VGRAQVVDLLQQELTAAEQRnQILSQQLQQME 300
Cdd:PRK04863   441 EDWLEEFQAKEQEATEellsLEQKLSVAQAAHSQFEQAYqlvrkiageVSRSEAWDVARELLRRLREQ-RHLAEQLQQLR 519

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  301 AEHNTLRNTVETEREESKILLE-KMELEVAErkLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQkhkaEMEEKTS 379
Cdd:PRK04863   520 MRLSELEQRLRQQQRAERLLAEfCKRLGKNL--DDEDELEQLQEELEARLESLSESVSEARERRMALRQ----QLEQLQA 593

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653  380 HILSLQKTGQELQSACDALKDqnsklLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 436
Cdd:PRK04863   594 RIQRLAARAPAWLAAQDALAR-----LREQSGEEFEDSQDVTEYMQQLLERERELTV 645
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2037-2206 6.81e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 6.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2037 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2112
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2113 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2169
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1034632653 2170 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2206
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1901-2773 2.36e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.36e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1901 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1970
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1971 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2043
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2044 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2120
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2121 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2198
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2199 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2276
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2277 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2353
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2354 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2425
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2426 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2505
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2506 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2585
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2586 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2665
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2666 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2741
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1034632653 2742 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2773
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1353-2180 2.47e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.47e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1353 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1432
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1433 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1509
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1510 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1589
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1590 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1669
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1670 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1749
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1750 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1829
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1830 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1903
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1904 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1983
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1984 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2062
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2063 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2142
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1034632653 2143 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2180
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1302-2087 4.78e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.05  E-value: 4.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1302 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQ 1380
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1381 iaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1457
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1458 QVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARGTIERLTKSLADVESQ 1526
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1527 VSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL--------------------------- 1579
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievaagnrln 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1580 ---TEDKEKLVKEIESLKSSKIAEST-----EWQEKHKELQKEYE-----ILL------QSYENVSNEAERIQHVVEAVr 1640
Cdd:TIGR02169  551 nvvVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEdgvigFAVdlvefdPKYEPAFKYVFGDTLVVEDI- 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1641 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMrkFAKSKQQKILELEEENDRLRAEVhpagdtakecmetllss 1720
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGIL--FSRSEPAELQRLRERLEGLKREL----------------- 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1721 nASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEatekhdnqtnvteegtqsipgetEEQ 1800
Cdd:TIGR02169  691 -SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-----------------------EDL 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1801 DSLSmstrptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTllSQISTK 1880
Cdd:TIGR02169  747 SSLE----------------------------QEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEI 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1881 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKN 1960
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1961 LKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR---------- 2030
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeels 952

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2031 ---YQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDT 2087
Cdd:TIGR02169  953 ledVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 759-1533 6.62e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.62e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  759 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 838
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  839 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 918
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  919 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 998
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  999 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1077
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1078 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1143
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1144 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1199
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1200 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1250
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1251 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1325
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1326 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1395
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1396 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1463
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632653 1464 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1533
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 763-1646 1.81e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 1.81e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  763 RAQVKQLEMNLAEAERQ-RRLDYESQTAHDNL-LTEQIHSLSIEAKSKDvkIEVLQNELDDVQLQFSEQSTLIRSLQSQL 840
Cdd:TIGR02168  185 RENLDRLEDILNELERQlKSLERQAEKAERYKeLKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  841 QNKESEvlegaervrhisskveelsqaLSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEE 920
Cdd:TIGR02168  263 QELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  921 KFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALI 1000
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1001 NRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDL 1080
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQEEL 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1081 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKP 1160
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDE 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1161 ELEEKILALekekeqLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIGDQL 1233
Cdd:TIGR02168  534 GYEAAIEAA------LGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAKDL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1234 RQLQIQVRESIDGKLpstdqqescsSTPGLEEPLFKATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQIKA 1309
Cdd:TIGR02168  608 VKFDPKLRKALSYLL----------GGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1310 QLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE 1389
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1390 lqpkldELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhtqlemqakehDERIKQLQVELCEMKqkpE 1469
Cdd:TIGR02168  758 ------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL-----------REALDELRAELTLLN---E 817

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1470 EIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERD 1549
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1550 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEstewqekhkELQKEYEILLQSYENVSNEA 1629
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIEDDE 967

                          890
                   ....*....|....*..
gi 1034632653 1630 ERIQHVVEAVRQEKQEL 1646
Cdd:TIGR02168  968 EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2016-2784 2.07e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 2.07e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2016 EKQQEVKQLQKDC----IRYQEKISALERTVKALEFVQTESQkdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2091
Cdd:TIGR02168  199 ERQLKSLERQAEKaeryKELKAELRELELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2092 ARVLADNLKLKKELQSnkesvksqMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2171
Cdd:TIGR02168  277 SELEEEIEELQKELYA--------LANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2172 EVQQLQENLDStvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEirlkedncSVLKDQLRQMSIHMEELK 2251
Cdd:TIGR02168  345 KLEELKEELES---LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2252 INISRLEHDKQIWESKAQ-TEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEK 2330
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2331 CKEQKGNLEGIIRQQEADIQN-SKFSY------EQLETDLQASRELTSRLHEEINM-------KEQKIISLLSgKEEAIQ 2396
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNqSGLSGilgvlsELISVDEGYEAAIEAALGGRLQAvvvenlnAAKKAIAFLK-QNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2397 VAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETL--KTIKKENIQQKAQL--------------- 2459
Cdd:TIGR02168  573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELakklrpgyrivtldg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2460 -------------DSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSEN 2526
Cdd:TIGR02168  653 dlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2527 AKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQN-------------KELENKYAKLEEKLKESEEANEDLRRSFNAL 2593
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2594 QEEKQDLSKEIESLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqkeaaKKV 2673
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERR--LEDLEEQIEELSEDIESLAAEIEELEELIEELESEL--------EAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2674 GEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFgrsmssLQNSRDHANEE 2753
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL------QERLSEEYSLT 952

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1034632653 2754 LDELKRKYDASLKELAQLKEQ-GLLNRERDAL 2784
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRlKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1306-2187 7.04e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.11  E-value: 7.04e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1306 QIKAQLKEIE-----AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1380
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1381 IAGLEH-LRELQPKLDELQKLISKKEEdvsylsgQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQv 1459
Cdd:TIGR02168  297 ISRLEQqKQILRERLANLERQLEELEA-------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE- 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1460 elcEMKQKPEEigeesrakqqiqrkLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESqvsaqnkekdtvlg 1539
Cdd:TIGR02168  369 ---ELESRLEE--------------LEEQLETLRSKVAQ---LELQIASLNNEIERLEARLERLED-------------- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1540 RLALLQEERDKLITEMDRSllENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQkEYEILL 1619
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1620 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1699
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1700 RAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLkhqiegnvsKQANLEATEKH 1779
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL---------DNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1780 DNQTNVTEEGTQSIPGETeeqdslsmstrptcsesvpSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKN 1859
Cdd:TIGR02168  643 PGYRIVTLDGDLVRPGGV-------------------ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1860 KEFSQTLENEKNTLLSQISTKDGELKMLQEEV----TKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNG 1935
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLarleAEVEQLEERIAQLSKELTELEAEIEELEERLEE-AEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1936 SIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLK 2015
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2016 EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-------KENLAQAVEHRKKAQAELASFKVLLDDTQ 2088
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2089 SEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ---------AEEKHLKEKKN-MQEKLDALRREKVHLEET 2158
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKERYDfLTAQKEDLTEAKETLEEA 1022

                          890       900       910
                   ....*....|....*....|....*....|
gi 1034632653 2159 IGEI-QVTLNKKDKEVQQLQENLDSTVTQL 2187
Cdd:TIGR02168 1023 IEEIdREARERFKDTFDQVNENFQRVFPKL 1052
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2119-2955 7.79e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 7.79e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2119 KDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLN------KKDKEVQQLQENLDSTvtQLAAF 2190
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELREL--ELALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2191 TKSMSSLQDDRDRVIDEAKKWERKFSDA---IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK 2267
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2268 AQTEVQLQQKVCDTLQgenkELLSQLEETrhlyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2347
Cdd:TIGR02168  311 LANLERQLEELEAQLE----ELESKLDEL-------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2348 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ----VAIAELRQQHDKEIKELENLLSQEeee 2423
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeAELKELQAELEELEEELEELQEEL--- 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2424 nivleeenkkavdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiilekdqlIQEAAA 2503
Cdd:TIGR02168  457 ---------------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG------------FSEGVK 509

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2504 ENNKLKEEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEA 2582
Cdd:TIGR02168  510 ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGN 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2583 NEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQV-------TALQ-----------------------------EEGT 2626
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldNALElakklrpgyrivtldgdlvrpggvitggsAKTN 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2627 LGLYHAQLKVKE--EEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETAEER 2704
Cdd:TIGR02168  670 SSILERRREIEEleEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2705 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDAL 2784
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2785 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqr 2864
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS-------- 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2865 saaqpstspAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhpLKAQLQEYQDKTKAFQIMQEELRQENLS 2944
Cdd:TIGR02168  901 ---------EELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEE 969

                          890
                   ....*....|.
gi 1034632653 2945 WQHELHQLRME 2955
Cdd:TIGR02168  970 ARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1304-2173 2.70e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.19  E-value: 2.70e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1304 VAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQgLEIESLKTVSHEAEVHA-----ESLQQKLESSQ 1378
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYEllkekEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1379 LQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-EAALTKIQTEIIEQEDLIKALHTQL---EMQAKEHDER 1453
Cdd:TIGR02169  244 RQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIaekERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1454 IKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEalkenkslqeELSLARGTIERLTKSLADVESQVSAQNKE 1533
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE----------ELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1534 KDTvlgrlalLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDkeklVKEIESLKSSKIAESTEWQEKHKELQK 1613
Cdd:TIGR02169  394 LEK-------LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK----INELEEEKEDKALEIKKQEWKLEQLAA 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1614 EYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1693
Cdd:TIGR02169  463 DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1694 -EENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVqDLKHQIEgNVSKQA- 1771
Cdd:TIGR02169  543 vAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLV-EFDPKYE-PAFKYVf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1772 -------NLEATEKH-DNQTNVTEEGtqsipgeteeqDSLSMSTRPTCSESVPSAKSANPAvskdfsshdeinNYLQQID 1843
Cdd:TIGR02169  621 gdtlvveDIEAARRLmGKYRMVTLEG-----------ELFEKSGAMTGGSRAPRGGILFSR------------SEPAELQ 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1844 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLS-------QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1916
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQelsdasrKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1917 EEKDDLEERlmnqLAELNGSIGNYCQDVTDaqIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 1996
Cdd:TIGR02169  758 SELKELEAR----IEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1997 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAE 2076
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2077 LASFKVLLDDTQsEAARVLADNLK----LKKELQSNKESVKS--QMKQKDEDLERRLEQAE----------EKHLKEKKN 2140
Cdd:TIGR02169  912 IEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnmlaiqeyEEVLKRLDE 990

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1034632653 2141 MQEKLDALRREKVHLEETIGEiqvtLNKKDKEV 2173
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEE----YEKKKREV 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1832-2529 3.97e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.97e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1832 HDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKL 1911
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1912 KETAEEEKDDLEERLMNQLAELNGS---IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1988
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1989 EYLE-KIQGAQKEPGNKSHAKELQELLK-EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTEsqkdLEITKENLAQA 2066
Cdd:TIGR02168  398 LNNEiERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2067 VEHRKKAQAELASFKVLLDDTQSEAARVL-----ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK----E 2137
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEgfsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2138 KKNMQEK-LDALRREKVH----LEETI---GEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL------QDDRDR 2203
Cdd:TIGR02168  554 NLNAAKKaIAFLKQNELGrvtfLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2204 VIDEAKKW-----------------------ERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLE-- 2258
Cdd:TIGR02168  634 ALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEee 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2259 ---------------HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTD 2323
Cdd:TIGR02168  714 leqlrkeleelsrqiSALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2324 LSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLlsgkeeaiQVAIAELR 2403
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL--------AAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2404 QQHDKEIKELENLLSQEEEENIVLEEENKKAvdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2483
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1034632653 2484 EERhlsiILEKDQLIQEAAAEN-NKLKEEIRGLRSHMDDLNSENAKL 2529
Cdd:TIGR02168  942 QER----LSEEYSLTLEEAEALeNKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1019 3.53e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 3.53e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  190 QQLQEKEEFISTLQAQLSQTQAEQAaqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLV 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL-----REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  270 GRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQF 349
Cdd:TIGR02168  288 KE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  350 EQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQ 429
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  430 KSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQIT 509
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  510 LLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEA 569
Cdd:TIGR02168  493 SLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNE 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  570 QEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTS 649
Cdd:TIGR02168  570 LGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  650 EEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQL 724
Cdd:TIGR02168  643 PGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  725 IEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIE 804
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEE 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  805 AKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLE 884
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  885 KKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ 961
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEV 936

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653  962 NYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1019
Cdd:TIGR02168  937 RIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1838-2621 1.19e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 1.19e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1838 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEE 1917
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1918 EKDDLEerlmNQLAELNGSIgnycqdvtdaqiknELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEylekiqgA 1997
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEEL-------E 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1998 QKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqTESQKDLEITKENLAQAVEHRKKA-QAE 2076
Cdd:TIGR02168  365 AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2077 LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKS------QMKQKDEDLERRLEQAEEKHLKEKKNMQEKLD---- 2146
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2147 -ALRREKVH--------LEETIGE-----IQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRD---------- 2202
Cdd:TIGR02168  522 lGVLSELISvdegyeaaIEAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDReilkniegfl 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2203 RVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkDQLRQM------------------SIHMEELKINISRLEHDKQIW 2264
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL-ELAKKLrpgyrivtldgdlvrpggVITGGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2265 ESKAQtevqlqqkvCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ 2344
Cdd:TIGR02168  681 ELEEK---------IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2345 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2424
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI--------EQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2425 IVLEEENKKAVDKTNQLMETLKTIKKENIQQK---AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---I 2498
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIEslaAEIEELEELIEELESELEALLNERASLEEALALLRSELEELseeL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2499 QEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLN--QVITIKDSQQKQLLEVQLQQN-----KELENKYAK 2571
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeYSLTLEEAEALENKIEDDEEEarrrlKRLENKIKE 983

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2572 LEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2621
Cdd:TIGR02168  984 LGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1834-2379 1.32e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.32e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1834 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1913
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1914 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1993
Cdd:COG1196    310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1994 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2073
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2074 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2149
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2150 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2229
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2230 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2302
Cdd:COG1196    629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653 2303 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2379
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1370-1937 2.13e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1370 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1449
Cdd:COG1196    218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1450 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1529
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1530 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1609
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1683
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1684 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1753
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1754 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1828
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1829 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1908
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1034632653 1909 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1937
Cdd:COG1196    773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 794-1764 7.22e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 7.22e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  794 LTEQIHSLSIEAKsKDVKIEVLQNELDDVQLQFSEQStlIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKEL 873
Cdd:TIGR02168  198 LERQLKSLERQAE-KAERYKELKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  874 EITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDN 953
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  954 EVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETE 1033
Cdd:TIGR02168  351 EELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL----QQE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1034 RGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQA 1113
Cdd:TIGR02168  423 IEELLKKLEEAELKE-------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1114 EISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKPELEEKILALekekeqLQKKLQEALTSRKAILKK 1193
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDEGYEAAIEAA------LGGRLQAVVVENLNAAKK 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1194 AQEkerhlreelkqqkddynrlqeqFDEQSKenenigdqLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLfkateq 1273
Cdd:TIGR02168  561 AIA----------------------FLKQNE--------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA------ 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1274 hhtqpvleSNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTseltkkseevfqlqEQINKQGLei 1353
Cdd:TIGR02168  605 --------KDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDG--------------DLVRPGGV-- 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1354 eslkTVSHEAEVHAESLQQKLEssqlqiaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQE 1433
Cdd:TIGR02168  661 ----ITGGSAKTNSSILERRRE-----------IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1434 DLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrKEALKENKSLQEELSLARGTI 1513
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-------AEAEAEIEELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1514 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESL 1593
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1594 ksskiaestewQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeqemee 1673
Cdd:TIGR02168  879 -----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE------------ 935

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1674 mkekmrkfakskqqkiLELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM--------------EYETLS 1739
Cdd:TIGR02168  936 ----------------VRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELK 999

                          970       980
                   ....*....|....*....|....*
gi 1034632653 1740 KKFQSLMSEKDSLSEEVQDLKHQIE 1764
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTEAKETLEEAIE 1024
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1306-1595 7.45e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 7.45e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1306 QIKAQLKEIEAEKVELELKvssttsELTKKSEEvfqLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL- 1384
Cdd:COG1196    217 ELKEELKELEAELLLLKLR------ELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAq 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1385 EHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1464
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1465 KQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALL 1544
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034632653 1545 QEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS 1595
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2454-3187 2.09e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.09e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2454 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2523
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2524 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2597
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2598 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2660
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2661 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2724
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2725 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2796
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2797 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2876
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2877 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2956
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2957 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3036
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 3037 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3116
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632653 3117 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3187
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1965-2789 2.36e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 2.36e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1965 VSELEEEKQQLVKEKTKVESEIRKEYL---EKIQGAQKEPGNKSHAKELQELLKEKQQ-EVKQLQKDCIRYQEKISALER 2040
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2041 TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAsfkvllDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKD 2120
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK------DLGEEEQLRVKEKIGELEAEIASLERSIAEK-EREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2121 EDLERRLEQAEE---KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK-------KDKEVQQLQENLDSTVTQLAAF 2190
Cdd:TIGR02169  318 EDAEERLAKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDlraeleeVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2191 TKSMSSLQDDRDRVIDEAKKWERKFSDAiqskEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQT 2270
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADL----NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2271 EVQLQQKVCDTLQGENKElLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ---------KGNLEGI 2341
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRE-LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaaGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2342 IRQQEADIQN----------SKFSYEQLeTDLQASRELTSRLHE-----------EINMKEQKII-----------SLLS 2389
Cdd:TIGR02169  553 VVEDDAVAKEaiellkrrkaGRATFLPL-NKMRDERRDLSILSEdgvigfavdlvEFDPKYEPAFkyvfgdtlvveDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2390 GKEEAIQVAIAELrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEniqqkaqLDSFVKSMSSL 2469
Cdd:TIGR02169  632 ARRLMGKYRMVTL----EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRE-------LSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2470 QNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE---EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITI 2546
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEleeDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2547 KDSQQKQLLEVQLQqnkELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-- 2624
Cdd:TIGR02169  781 LNDLEARLSHSRIP---EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEie 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2625 ---GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKELKHLhhdaGIMRNETETA 2701
Cdd:TIGR02169  858 nlnGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL----RELERKIEELEAQIEKKRKRL----SELKAKLEAL 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2702 EERVAELARDLVEMEQKLLMVTKENKgLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEqgllnrER 2781
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE------ER 1002


                   ....*...
gi 1034632653 2782 DALLSETA 2789
Cdd:TIGR02169 1003 KAILERIE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1570-2378 9.54e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 9.54e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1570 ESLKLALegLTEDKEKLVKEIESLKSSKIAESTEW---QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQEL 1646
Cdd:TIGR02168  223 RELELAL--LVLRLEELREELEELQEELKEAEEELeelTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1647 YGKLRSTEANKKETEKQLQEAEQEMEEMkekmrkfakskQQKILELEEENDRLRAEVhpagDTAKECMETLLSSNASMKE 1726
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEEL-----------ESKLDELAEELAELEEKL----EELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1727 ELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEAtEKHDNQTNVTEEGTQSIPGETEEQDSLSMS 1806
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED-RRERLQQEIEELLKKLEEAELKELQAELEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1807 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ----QIDQLKERIAGLEEEKQKNKEFSQTLENEKN----------T 1872
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDaaerELAQLQARLDSLERLQENLEGFSEGVKALLKnqsglsgilgV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1873 LLSQISTKDG---------ELKMLQEEVTKMNLLNQQI----QEELSRVTKLKETAEEEkDDLEERLMNQLAELNGSIGn 1939
Cdd:TIGR02168  525 LSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIaflkQNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1940 YCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA---------KEL 2010
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2011 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvlLDDTQSE 2090
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2091 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2170
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2171 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWerkfSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2250
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2251 KINISRL-EHDKQIWESKAQTEVQLQQkvcdTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN--- 2326
Cdd:TIGR02168  914 RRELEELrEKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnl 989

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 2327 -SLEKCKEQKGNLEgIIRQQEADIQNSKFSYEQLETDLqaSRELTSRLHEEIN 2378
Cdd:TIGR02168  990 aAIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEI--DREARERFKDTFD 1039
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1165-1988 1.32e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 1.32e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1165 KILALEKEKEQLQKKLQEALTSRKAILKKAQEKErhlrEELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsi 1244
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-- 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1245 dgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASAlqggtSVAQIKAQLKEIEAEKVELELK 1324
Cdd:TIGR02168  307 --------LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE-----ELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1325 VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKK 1404
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1405 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMqAKEHDERIKQLQVELCEMKQKPEEI-GEESRAKQQIQR 1483
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLsGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1484 K--------------LQAALISRKEALKENKSLQEELSLARGTIERLT-KSLADVESQVSAQNKEKDTVLGRLALLQEER 1548
Cdd:TIGR02168  532 DegyeaaieaalggrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDsIKGTEIQGNDREILKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1549 DKLITEMDRSLlenqSLSSSCESLKLALEGL----------TEDKEKL---------VKEIESLKSSKIAESTEWQEKHK 1609
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAkklrpgyrivTLDGDLVrpggvitggSAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI 1689
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1690 LELEEENDRLrAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvsk 1769
Cdd:TIGR02168  768 ERLEEAEEEL-AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----- 841

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1770 qanlEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptcsesvpsaksanpavskdfssHDEINNYLQQIDQLKERI 1849
Cdd:TIGR02168  842 ----DLEEQIEELSEDIESLAAEIEELEELIEEL----------------------------ESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1850 AGLEEEKQKnkefsqtLENEKNTLLSQISTKDGELKMLQEEVTKMNL----LNQQIQEELSRVTKLKETAEEEKDDLEER 1925
Cdd:TIGR02168  890 ALLRSELEE-------LSEELRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYSLTLEEAEALENK 962

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 1926 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1988
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 809-1650 1.99e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 1.99e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  809 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEvLEGAERVRHISSKVEELSQALSQKELEitKMDQLLLEKKRD 888
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKE--ALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  889 VETLQQTIEEKDQQVTEISFSMTEKMVQLNE-----------EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSS 957
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  958 GLKQNYDEMspagQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESK---KEIPLSETER 1034
Cdd:TIGR02169  326 KLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdyrEKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1035 GEVEEDKENKEYSEKCVTSKCQEIEIYLKQtISEKEVELQHIRKDLEEKLAAEE----QFQALVKQMNQTLQDKTNQIDL 1110
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAG-IEAKINELEEEKEDKALEIKKQEwkleQLAADLSKYEQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1111 LQAEISENQAIIQKLITSNTDASD--GDSVALVKETVVISPPCTGSSEHWKPELEEKILALEK-----------EKEQLQ 1177
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEErvRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVaagnrlnnvvvEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1178 KKLQEALTSRKA------ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE--NENIGDQL--------RQLQIQVR 1241
Cdd:TIGR02169  561 KEAIELLKRRKAgratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafKYVFGDTLvvedieaaRRLMGKYR 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1242 E-SIDGKLpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESnLCPDWPSHSEDASALQGGTS-----VAQIKAQLKEIE 1315
Cdd:TIGR02169  641 MvTLEGEL----FEKSGAMTGGSRAPRGGILFSRSEPAELQR-LRERLEGLKRELSSLQSELRrienrLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1316 AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlRELQPKLD 1395
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-RLSHSRIP 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1396 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEES 1475
Cdd:TIGR02169  795 EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI----DLKEQIKSIEKEIENLNGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1476 RAKQQIQRKLQAALISRKealKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERdklitem 1555
Cdd:TIGR02169  871 EELEAALRDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK------- 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1556 dRSLLENQSLSSSCESLKLALEGLTEDKEKL----VKEIESLKSSKiAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1631
Cdd:TIGR02169  941 -GEDEEIPEEELSLEDVQAELQRVEEEIRALepvnMLAIQEYEEVL-KRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018

                          890       900
                   ....*....|....*....|
gi 1034632653 1632 I-QHVVEAVRQEKQELYGKL 1650
Cdd:TIGR02169 1019 VfMEAFEAINENFNEIFAEL 1038
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2007-2607 2.51e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.97  E-value: 2.51e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2007 AKELQELLKEKQQEVKQLQKDciRYQEKISALERTVKALEfvqtesqkdleitkENLAQAVEHRKKAQAELASFKVLLDD 2086
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR--ELEAELEELEAELEELE--------------AELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2087 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV 2164
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2165 TLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRvideakkwerkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMS 2244
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2245 IHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDL 2324
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2325 SNSLEKCKEQKGNLE-GIIRQQEADIQNSKFSYEQ-LETDLQASRELTSRLHEEInmkEQKIISLLSGKEEAiQVAIAEL 2402
Cdd:COG1196    504 EGFLEGVKAALLLAGlRGLAGAVAVLIGVEAAYEAaLEAALAAALQNIVVEDDEV---AAAAIEYLKAAKAG-RATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2403 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLktikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2482
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL----LGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2483 LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQN 2562
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1034632653 2563 KELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESL 2607
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 759-1120 3.42e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  759 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 838
Cdd:COG1196    195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  839 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 918
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  919 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 998
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  999 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1078
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1034632653 1079 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1120
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1495-2088 1.54e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1495 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1571
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1572 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1642
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1643 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1722
Cdd:PRK03918   323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1723 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1797
Cdd:PRK03918   384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1798 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1876
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1877 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1956
Cdd:PRK03918   534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1957 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 2035
Cdd:PRK03918   603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 2036 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2088
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 683-1256 1.68e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  683 QDELERLKSQILELElnfhKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKelsmvtEL 762
Cdd:COG1196    238 EAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  763 RAQVKQLEMNLAEAERQRrldyESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN 842
Cdd:COG1196    308 EERRRELEERLEELEEEL----AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  843 KESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKF 922
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  923 SLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEelqhefdllkKENEQRKRKLQAALInr 1002
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA----------ALLLAGLRGLAGAVA-- 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1003 kELLQRVSRLEEELANLKDESKKEIPLSETERGE--VEEDKENKEysekcvtskcqeieiyLKQTISEKEVELQHIRKDL 1080
Cdd:COG1196    528 -VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaIEYLKAAKA----------------GRATFLPLDKIRARAALAA 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1081 EEKLAAEEQFQALVKQMNQTLQDK-TNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWK 1159
Cdd:COG1196    591 ALARGAIGAAVDLVASDLREADARyYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1160 PELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQ 1239
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                          570
                   ....*....|....*..
gi 1034632653 1240 VRESIDGKLPSTDQQES 1256
Cdd:COG1196    751 EALEELPEPPDLEELER 767
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1842-2624 3.20e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 3.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1842 IDQLKERIAGLEEEKQKNKEFSQTLE-----------NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTK 1910
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKekreyegyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1911 LKETAEEEKDDLEERLMNQLaelngsignycqdvtdaQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEy 1990
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1991 lekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHR 2070
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-------KEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2071 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsQMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRR 2150
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWK----LEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2151 EKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRV---IDEAKKWERKFSDAIQS------ 2221
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVaagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2222 -----------KEEEIRLKEDNCS--------VLKDQLRQMSIHMEE--LKINISRLEHDKQ-------------IWESK 2267
Cdd:TIGR02169  550 nnvvveddavaKEAIELLKRRKAGratflplnKMRDERRDLSILSEDgvIGFAVDLVEFDPKyepafkyvfgdtlVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2268 AQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2347
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2348 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQqhdkEIKELENLLSQEEEenivl 2427
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL--------SSLEQEIENVKS----ELKELEARIEELEE----- 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2428 eeenkkavdKTNQLMETLKTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---IQEAAAE 2504
Cdd:TIGR02169  773 ---------DLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2505 NNKLKEEIRGLRSHMDDLNSENAKLDAELiqyredlnqvitikdsqqkqllevqlqqnKELENKYAKLEEKLKESEEANE 2584
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLNGKKEELEEEL-----------------------------EELEAALRDLESRLGDLKKERD 892

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1034632653 2585 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2624
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 635-1230 4.73e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 4.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  635 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 714
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  715 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 794
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  795 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 867
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  868 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 947
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  948 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 1003
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1004 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1080
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1081 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1160
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1161 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1230
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 48-925 4.97e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 4.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653   48 EDVQERLAYAEQLVVELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQpaqsstemEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI--------SRLEQQKQILRERLANLERQLEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  208 QTQAEQAAQqvvREKDARFETQVRLHEDELLQLVTQADVE-TEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAE 286
Cdd:TIGR02168  323 AQLEELESK---LDELAEELAELEEKLEELKEELESLEAElEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  287 QRNQILSQQLQQMEAEHNTLRNTVETEREE-SKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSA 365
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  366 LEQKHKAEMEEKTShILSLQKTGQELQSACDALKDQNSKLLQDKN------------EQAVQSA--QTIQQLEDQLQQKS 431
Cdd:TIGR02168  480 AERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvdegyEAAIEAAlgGRLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  432 KEISQFLnrlplQQHETASQTSFPdvynegtqaVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI--- 508
Cdd:TIGR02168  559 KKAIAFL-----KQNELGRVTFLP---------LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgg 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  509 -----TLLEAQNRTGEADREVSEISIV-DIANKRSSSAEESGQDVLeNTFSQKhKELSVLLLEMKEAQEEIAFLKLQLQg 582
Cdd:TIGR02168  625 vlvvdDLDNALELAKKLRPGYRIVTLDgDLVRPGGVITGGSAKTNS-SILERR-REIEELEEKIEELEEKIAELEKALA- 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  583 kRAEEADHEVLDQKEMKQMEGEGIapikmkvfledtgqdfplmpNEESSLPAVEKEQASTEHQSRTSEEISLndagvelk 662
Cdd:TIGR02168  702 -ELRKELEELEEELEQLRKELEEL--------------------SRQISALRKDLARLEAEVEQLEERIAQL-------- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  663 stkqdgdkslsavpdigqchQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFTAL 742
Cdd:TIGR02168  753 --------------------SKELTELEAEIEELEERLEEAEE----ELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  743 SEErdqlLSQVKELsmVTELRAQVKQLEMNLAEAERQ-RRLDYESQTahdnlLTEQIHSLSIEAKSKDVKIEVLQNELDD 821
Cdd:TIGR02168  809 RAE----LTLLNEE--AANLRERLESLERRIAATERRlEDLEEQIEE-----LSEDIESLAAEIEELEELIEELESELEA 877

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  822 VQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKR----DVETLQQTIE 897
Cdd:TIGR02168  878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTLEEAE 957

                          890       900
                   ....*....|....*....|....*...
gi 1034632653  898 EKDQQVTEISFSMTEKMVQLNEEKFSLG 925
Cdd:TIGR02168  958 ALENKIEDDEEEARRRLKRLENKIKELG 985
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 756-1487 7.94e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 7.94e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  756 LSMVTELRAQVKQLEMNLAEAER-----QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVlQNELDDVQLQFSEQS 830
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEeleklTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-KEKIGELEAEIASLE 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  831 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEisfsM 910
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE----T 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  911 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQnydemspagqiSKEELQHEFDLLKKENEQ 990
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  991 RKRKLQAALINRKELLQRVSRLEEELANLKDE---SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS 1067
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEYDRVEKElskLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1068 EKE-----VE------LQHIRKDLEEKLAAEEQFQALVK----------QMNQTLQDKT---------NQIDLL----QA 1113
Cdd:TIGR02169  533 VGEryataIEvaagnrLNNVVVEDDAVAKEAIELLKRRKagratflplnKMRDERRDLSilsedgvigFAVDLVefdpKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1114 EISENQAIIQKLITSNTDASD--GDSVALVK---ETVVISPPCTGSS------EHWKPELEEKILALEKEKEQLQKKLQE 1182
Cdd:TIGR02169  613 EPAFKYVFGDTLVVEDIEAARrlMGKYRMVTlegELFEKSGAMTGGSraprggILFSRSEPAELQRLRERLEGLKRELSS 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1183 ALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKlpsTDQQESCSSTPG 1262
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK---SELKELEARIEE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1263 LEEPLFKATEQhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQL 1342
Cdd:TIGR02169  770 LEEDLHKLEEA------------------LNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1343 QEqinkqglEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAA 1421
Cdd:TIGR02169  832 EK-------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653 1422 LTKIQTEIIEQEDLIKALHTQLEMQAkehdERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQA 1487
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1839-2339 1.14e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.31  E-value: 1.14e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1839 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1918
Cdd:PRK03918   230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1919 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1992
Cdd:PRK03918   309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1993 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2060
Cdd:PRK03918   388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2061 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2140
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2141 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2210
Cdd:PRK03918   541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2211 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2290
Cdd:PRK03918   621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632653 2291 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2339
Cdd:PRK03918   662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2220-2771 1.21e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.21e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2220 QSKEEEIRLKEDNCSVLKDQLRQMSIhmEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2299
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2300 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2379
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2380 KEQKIISLLSGKEEA-------------IQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLK 2446
Cdd:COG1196    370 AEAELAEAEEELEELaeellealraaaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2447 TIKK---ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSII-LEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2522
Cdd:COG1196    450 EEAEleeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2523 NSENAKLDAELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2601
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2602 KEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLK 2681
Cdd:COG1196    610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2682 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2761
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                          570
                   ....*....|
gi 1034632653 2762 DASLKELAQL 2771
Cdd:COG1196    770 ERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2051-2662 1.73e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2051 ESQKDLEITKENLAQA----VEHRK-----KAQAELAsfkvllddtqsEAARVLADNLKLKK-ELQSNKESVKSQMKQKD 2120
Cdd:COG1196    176 EAERKLEATEENLERLedilGELERqleplERQAEKA-----------ERYRELKEELKELEaELLLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2121 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAftksmssLQDD 2200
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE-------LEER 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2201 RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2280
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2281 TLQgENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE 2360
Cdd:COG1196    398 LAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2361 TDLQASRELTSRLHEEINMKEQkIISLLSGKEEAIQvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2440
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLE-AEADYEGFLEGVK-AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2441 LMETLKTIKKENIQQKAQLDSF-----VKSMSSLQNDRDRIVGDYQQLEERHLSIILE-KDQLIQEAAAENNKLKEEIRG 2514
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFlpldkIRARAALAAALARGAIGAAVDLVASDLREADaRYYVLGDTLLGRTLVAARLEA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2515 LRSHMDDLNSENAKLDAELIQyREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2594
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEG-GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653 2595 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRlsalfSSSQKRIAELEEEL 2662
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLEREI 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1833-2617 2.20e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 2.20e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1833 DEINNYLQQIDQLKERIAGLEEEKQKN-KEFSQTLENEKNTLLSQISTKDGELKMLQEEVTK-----------MNLLNQQ 1900
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKleaeidkllaeIEELERE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1901 IQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKT 1980
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELED-LRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1981 KVESEIrkeylEKIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEItK 2060
Cdd:TIGR02169  424 DLNAAI-----AGIEAKINE--LEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-A 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2061 ENLAQAVEHRkkaQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ----KDEDL---------ERRL 2127
Cdd:TIGR02169  496 EAQARASEER---VRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvvEDDAVakeaiellkRRKA 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2128 EQAEEKHLKEKKNMQEKLDALRREKVHleetigEIQVTLNKKDKEVQQ----------LQENLDSTVTQLAAFtkSMSSL 2197
Cdd:TIGR02169  573 GRATFLPLNKMRDERRDLSILSEDGVI------GFAVDLVEFDPKYEPafkyvfgdtlVVEDIEAARRLMGKY--RMVTL 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2198 QDD----RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiNISRLEHDKQIWESKAQTEVQ 2273
Cdd:TIGR02169  645 EGElfekSGAMTGGSRAPRGGILFSRSEPAELQRLRER----LEGLKRELSSLQSELR-RIENRLDELSQELSDASRKIG 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2274 LQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEadIQNSK 2353
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2354 FSYEQLETDLQASRELTSRLHEEINMKEQKiisllsgkeeaiqvaiaelRQQHDKEIKELENLLsqeeEENIVLEEENKK 2433
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLE-------------------KEYLEKEIQELQEQR----IDLKEQIKSIEK 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2434 AVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAENNKLKEEIR 2513
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLE---SRLGDLKKERDELEAQLRELERK-----------IEELEAQIEKKRKRLS 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2514 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK-QLLEVQLQQNKELENKYAKLEeklkeseeanEDLRRSFNA 2592
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNMLAIQEY----------EEVLKRLDE 990

                          810       820
                   ....*....|....*....|....*
gi 1034632653 2593 LQEEKQDLSKEIESLKVSISQLTRQ 2617
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1627-2402 3.59e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 3.59e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1627 NEAERIQHVVEAVRQ-EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHP 1705
Cdd:TIGR02169  208 EKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1706 AGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDnqtnv 1785
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL----- 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1786 tEEGTQSIPGETEEQDSLSMSTRptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1865
Cdd:TIGR02169  363 -KEELEDLRAELEEVDKEFAETR------------------------DELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1866 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlaelngsignycqdvt 1945
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY------------------- 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1946 daqiknELLESEMKNLKKCVSELEEEKQQLVKEKT--KVESEIRKEYLEKIQGAQKEPG--NKSHAKELQELLKEKQQEV 2021
Cdd:TIGR02169  479 ------DRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGTVAQLGsvGERYATAIEVAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2022 ----KQLQKDCIRYQEKISALERTVKALEFVQTEsQKDLEITKEN-----LAQAVEHRKKAQaelASFKVLLDDT----Q 2088
Cdd:TIGR02169  553 vvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEDgvigfAVDLVEFDPKYE---PAFKYVFGDTlvveD 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2089 SEAARVLADNLKL--------------------KKELQSNKESVKSQMKQKDEDLErRLEQAEEKHLKEKKNMQEKLDAL 2148
Cdd:TIGR02169  629 IEAARRLMGKYRMvtlegelfeksgamtggsraPRGGILFSRSEPAELQRLRERLE-GLKRELSSLQSELRRIENRLDEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2149 RREKVHLEETIGEIQvtlnkkdKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQSKEEEIRL 2228
Cdd:TIGR02169  708 SQELSDASRKIGEIE-------KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR----IEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2229 KEDNCSVLKDQLRQMSI-----HMEELKINISRLE----HDKQIWESKAQTEVQLQQKVcDTLQGENKELLSQLEETRHL 2299
Cdd:TIGR02169  777 LEEALNDLEARLSHSRIpeiqaELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEI-QELQEQRIDLKEQIKSIEKE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2300 YHSSQNELAKLESELKSLKDQLTDLSnslekckEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2379
Cdd:TIGR02169  856 IENLNGKKEELEEELEELEAALRDLE-------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          810       820
                   ....*....|....*....|...
gi 1034632653 2380 KEQKIISLLSGKEEAIQVAIAEL 2402
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEEL 951
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 555-1245 4.02e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 4.02e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  555 KHKELSVLLLEMKEAQEEIAFLKLQLqgkraEEADHEVLDQKEMKQMEGEGIAPIKMKVFledtgqdfplmpneesslpa 634
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEEL-----KEAEEELEELTAELQELEEKLEELRLEVS-------------------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  635 vEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYE--- 708
Cdd:TIGR02168  278 -ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelk 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  709 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaERQRRLDYESQ 787
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  788 TAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ- 866
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGf 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  867 -----ALSQKELEITKMDQLLLEK-------KRDVET-----LQQTIEEKDQQVTEISFSMTEK-----------MVQLN 918
Cdd:TIGR02168  505 segvkALLKNQSGLSGILGVLSELisvdegyEAAIEAalggrLQAVVVENLNAAKKAIAFLKQNelgrvtflpldSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  919 EEKFSLGVEIKTLKEQLNLLSRAEEAKK----------------EQVEEDNEVSSGLKQNY-------DEMSPAGQISKE 975
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGVITGG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  976 ELQHEFDLLK-----KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKC 1050
Cdd:TIGR02168  665 SAKTNSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1051 VTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAE---EQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLit 1127
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL-- 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1128 SNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREE 1204
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLeeaLALLRSELEELSEE 902

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1034632653 1205 LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESID 1245
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2170-2923 4.36e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 4.36e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2170 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERkfSDAIQSKEEEIRLKEdncsvLKDQLRQMSIHMEE 2249
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2250 LKINISRLEhdkqiwESKAQTEVQLQQKVCDTlqGENKELLSQLEEtrHLYHSSQNELAKLESELKSLKDQLTDLSNSLE 2329
Cdd:TIGR02169  242 IERQLASLE------EELEKLTEEISELEKRL--EEIEQLLEELNK--KIKDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2330 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSgKEEAIQVAIAELRQQHDKE 2409
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-ELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2410 IKELENL-----------------LSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQND 2472
Cdd:TIGR02169  391 REKLEKLkreinelkreldrlqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2473 RDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENA---KLDAELIQYRED---------- 2539
Cdd:TIGR02169  471 LYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2540 --LNQVITIKDSQQKQLLEVqLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQ 2617
Cdd:TIGR02169  547 nrLNNVVVEDDAVAKEAIEL-LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2618 VTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSqkRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNE 2697
Cdd:TIGR02169  626 VEDIEAARRLMGKYRMVTLEGELFEKSGAMTGGS--RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2698 TETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKrkydaslKELAQLKEQglL 2777
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE-------ARIEELEED--L 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2778 NRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2857
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2858 SEEG----KQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQE 2923
Cdd:TIGR02169  855 EIENlngkKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA 924
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1832-2545 8.75e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 61.99  E-value: 8.75e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1832 HDEINNYLQQIDQL-KERIAGLEEEKQKNKEFSQTLENEKNTLLSQIS----TKDGELKMlQEEVTKMN----LLNQQIQ 1902
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNfddfGKEENIKY-ADEINKIKddikNLDQKID 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1903 EELSRVTKLKETAEEEKDDLEERLmnqlaelngsigNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK------QQLV 1976
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQI------------NDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKniydeiKKLL 1196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1977 KEKTKVESEirKEYLEKIQGAqkepgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERTVKALEFVQTESQKD 2055
Cdd:TIGR01612 1197 NEIAEIEKD--KTSLEEVKGI-----NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAyIEDLDEIKEKSPEIENEMGIE 1269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2056 LEITKENLAQAVEHRKKAQAELASFK--VLLDDTQSEAARVLADNLK------LKKELQSNKesvkSQMKQKDEDLERRL 2127
Cdd:TIGR01612 1270 MDIKAEMETFNISHDDDKDHHIISKKhdENISDIREKSLKIIEDFSEesdindIKKELQKNL----LDAQKHNSDINLYL 1345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2128 EQ-AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDstvtqLAAFTKSMSSLQDDRDrvID 2206
Cdd:TIGR01612 1346 NEiANIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN-----LEECKSKIESTLDDKD--ID 1418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2207 EAKKWERKFSDAIQSKEEEI-----RLKEDNCSVLK-----DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEvqlQQ 2276
Cdd:TIGR01612 1419 ECIKKIKELKNHILSEESNIdtyfkNADENNENVLLlfkniEMADNKSQHILKIKKDNATNDHDFNINELKEHID---KS 1495

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2277 KVCDTLQGENKEllsQLEETRHLYHSSQNELAKL-----ESELKSLKDQLTDLSNSL-EKCKEQKGNL---EGIIRQQEA 2347
Cdd:TIGR01612 1496 KGCKDEADKNAK---AIEKNKELFEQYKKDVTELlnkysALAIKNKFAKTKKDSEIIiKEIKDAHKKFileAEKSEQKIK 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2348 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISllsgkeeaiqvaIAELRQQHDKEIKELENLLSQEEE----E 2423
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK------------ISDIKKKINDCLKETESIEKKISSfsidS 1640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2424 NIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQqleerhLSIIlekDQLIQEAAA 2503
Cdd:TIGR01612 1641 QDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYE------IGII---EKIKEIAIA 1711

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1034632653 2504 ENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVIT 2545
Cdd:TIGR01612 1712 NKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNT 1753
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 683-1211 1.07e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 1.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  683 QDELERLKSQILELELNFHKAQE---IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SM 758
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAeeyELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELeEE 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  759 VTELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlltEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 838
Cdd:COG1196    346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  839 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM-TEKMVQL 917
Cdd:COG1196    422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlLLLEAEA 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  918 NEEKFSLGVEIKTLKEQLNLLSRA------EEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISkeelqhefDLLKKENEQR 991
Cdd:COG1196    502 DYEGFLEGVKAALLLAGLRGLAGAvavligVEAAYEAALEAALAAALQNIVVEDDEVAAAAI--------EYLKAAKAGR 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  992 KRKLQAALINRKELLQRVSRLEEEL-------ANLKDESKKEIPLSETERGE--VEEDKENKEYSEKCVTSKCQEIEIYL 1062
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGaavdlvaSDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLEG 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1063 KQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVK 1142
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653 1143 ETVVISPPCTGSSEHwkPELEEKILALEKEKEQLQKKLQEALTSRK--------AILKKAQEKERHlrEELKQQKDD 1211
Cdd:COG1196    734 REELLEELLEEEELL--EEEALEELPEPPDLEELERELERLEREIEalgpvnllAIEEYEELEERY--DFLSEQRED 806
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1842-2157 1.09e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 1.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1842 IDQLKERIAGLEEEKQKNKEFsQTLENEKNTL-----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1916
Cdd:COG1196    195 LGELERQLEPLERQAEKAERY-RELKEELKELeaellLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1917 EEKDDLEERLmnqlaelngsignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 1996
Cdd:COG1196    274 LELEELELEL------------------EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1997 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITK---ENLAQAVEHRKKA 2073
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaqlEELEEAEEALLER 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2074 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2153
Cdd:COG1196    416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495


                   ....
gi 1034632653 2154 HLEE 2157
Cdd:COG1196    496 LLEA 499
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2304-2773 1.12e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.19  E-value: 1.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2304 QNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE--EINMKE 2381
Cdd:TIGR04523  151 EKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISElkKQNNQL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2382 QKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDS 2461
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2462 FVKSmsSLQNDRDRIVGDYQQLEERHLSIilekdqliqeaaaenNKLKEEIRGLRSHMDDLNSENAKLDAELiqyREDLN 2541
Cdd:TIGR04523  311 ELKS--ELKNQEKKLEEIQNQISQNNKII---------------SQLNEQISQLKKELTNSESENSEKQREL---EEKQN 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2542 QVITIKDSQQKQLlevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2621
Cdd:TIGR04523  371 EIEKLKKENQSYK-----QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2622 QEEGTlglyhaqlkVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETA 2701
Cdd:TIGR04523  446 TNQDS---------VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-EKELKKLNEEKKELEEKVKDL 515

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632653 2702 EERVAELARDLVEMEQKLLMVTKENKGLTAQIQS--FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2773
Cdd:TIGR04523  516 TKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 866-1763 1.84e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 60.76  E-value: 1.84e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  866 QALSQKELEITKMDQLL---LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKfslgVEIKTLKEQLNLLSRAE 942
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAagsRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKE----QAKKALEYYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  943 EAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 1022
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1023 SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS--EKEVELQHIRKDLEEKLAAEEQFQALVKQMNQT 1100
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKEleIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1101 LQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDsvalvketvvisppctgssEHWKPELEEKILALEKEKEQLQKKL 1180
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL-------------------EDLLKEEKKEELEILEEEEESIELK 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1181 QEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSST 1260
Cdd:pfam02463  443 QGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1261 PGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVF 1340
Cdd:pfam02463  523 RIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1341 QLQEQINKQGLEIESLKTVSHEAEVHAESLQQK--LESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVS--YLSGQLS 1416
Cdd:pfam02463  603 LNLAQLDKATLEADEDDKRAKVVEGILKDTELTklKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKelLEIQELQ 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1417 EKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL 1496
Cdd:pfam02463  683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1497 KENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLAL 1576
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE----LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1577 EGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERiqhvvEAVRQEKQELYGKLRSTEAN 1656
Cdd:pfam02463  839 ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE-----KEKEEKKELEEESQKLNLLE 913

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1657 KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpaGDTAKECMETLLSSNASMKEELERVKMEYE 1736
Cdd:pfam02463  914 EKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER--NKRLLLAKEELGKVNLMAIEEFEEKEERYN 991

                          890       900
                   ....*....|....*....|....*..
gi 1034632653 1737 TLSKKFQSLMSEKDSLSEEVQDLKHQI 1763
Cdd:pfam02463  992 KDELEKERLEEEKKKLIRAIIEETCQR 1018
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1829-2046 1.91e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 1.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1829 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEvtkMNLLNQQIQEELSRV 1908
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE---LAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1909 TKLKETAEEEKDDLEERL-----MNQLAELNGSIGNycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1983
Cdd:COG4942     93 AELRAELEAQKEELAELLralyrLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 1984 SEiRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2046
Cdd:COG4942    171 AE-RAELEALLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
PTZ00121 PTZ00121
MAEBL; Provisional
 1588-2382 2.04e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 2.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1588 KEIESLKSSKIAESTEWQEKHKELQKEYEilLQSYENVsNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1667
Cdd:PTZ00121  1164 RKAEEARKAEDAKKAEAARKAEEVRKAEE--LRKAEDA-RKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE 1240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1668 EQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERV---------KMEYETL 1738
Cdd:PTZ00121  1241 EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKAdeakkkaeeAKKADEA 1320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1739 SKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQanleatEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTcSESVPSA 1818
Cdd:PTZ00121  1321 KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA------EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK-AEEKKKA 1393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1819 KSANPAVSKDFSSHDEINNYL---QQIDQLK---ERIAGLEEEKQKNKEFSQTLENEKNtllSQISTKDGELKMLQEEVT 1892
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAaakKKADEAKkkaEEKKKADEAKKKAEEAKKADEAKKK---AEEAKKAEEAKKKAEEAK 1470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1893 KMNLLNQQiQEELSRVTKLKETAEEEKDDLEErlmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK 1972
Cdd:PTZ00121  1471 KADEAKKK-AEEAKKADEAKKKAEEAKKKADE------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAE 1543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1973 QQLVKEKTKVESEIRK-EYLEKIQGAQKEpgnkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTE 2051
Cdd:PTZ00121  1544 EKKKADELKKAEELKKaEEKKKAEEAKKA-------EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE 1616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2052 SQKdleITKENLAQAVEHRKKaqAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK---ESVKSQMKQKDEDLERRLE 2128
Cdd:PTZ00121  1617 EAK---IKAEELKKAEEEKKK--VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKaeeDKKKAEEAKKAEEDEKKAA 1691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2129 QAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD---KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVI 2205
Cdd:PTZ00121  1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEeakKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2206 DEAKKWERKFSDAIQSKEEEIRLKEDNcsVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDtlqgE 2285
Cdd:PTZ00121  1772 EIRKEKEAVIEEELDEEDEKRRMEVDK--KIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLE----E 1845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2286 NKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQA 2365
Cdd:PTZ00121  1846 ADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYI 1925

                          810
                   ....*....|....*..
gi 1034632653 2366 SRELTSRLHEEINMKEQ 2382
Cdd:PTZ00121  1926 KRDAEETREEIIKISKK 1942
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1161-1652 2.04e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 2.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1161 ELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKerhlREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1240
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1241 ---RESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpDWPSHSEDASALQGgtSVAQIKAQLKEIEAE 1317
Cdd:PRK02224   289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV--AAQAHNEEAESLRE--DADDLEERAEELREE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1318 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDE 1396
Cdd:PRK02224   365 AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1397 LQKL---------------------ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKA------LHTQLEMQAK- 1448
Cdd:PRK02224   445 AEALleagkcpecgqpvegsphvetIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedrierLEERREDLEEl 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1449 --EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVES- 1525
Cdd:PRK02224   525 iaERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1526 ---------QVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN-----QSLSSSCESLKLALEGLTEDKEKLVKEIE 1591
Cdd:PRK02224   605 edeierlreKREALAELNDERRERLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIG 684

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632653 1592 SLKSSkIAESTEWQEKHKELQKEYEILLQSYENVSneaeriqhvveavrqEKQELYGKLRS 1652
Cdd:PRK02224   685 AVENE-LEELEELRERREALENRVEALEALYDEAE---------------ELESMYGDLRA 729
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2213-2773 2.05e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 2.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2213 RKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQiwesKAQTEVQLQQKvcdTLQGENKELLSQ 2292
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLA---ELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2293 LEETRHLyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSR 2372
Cdd:COG1196    308 EERRREL----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2373 LHEEINMKEQKIISLLSGKEEAIQV--AIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKK 2450
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAeeALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2451 ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD 2530
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLE------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2531 AELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKV 2609
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2610 SISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHH 2689
Cdd:COG1196    618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2690 DAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG---------------------RSMSSLQNSRD 2748
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEelleeealeelpeppdleeleRELERLEREIE 777

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1034632653 2749 H-------ANEELDELKRKYDASLKELAQLKE 2773
Cdd:COG1196    778 AlgpvnllAIEEYEELEERYDFLSEQREDLEE 809
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1415-1934 4.19e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 4.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1415 LSEKEAALTKIQTEI--IEQEDLIKALHTqLEMQAKEHDERIKQLQVE---LCEMKQKPEEIGEESRAKQQIQRKLQAAL 1489
Cdd:PRK02224   182 LSDQRGSLDQLKAQIeeKEEKDLHERLNG-LESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1490 ----ISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSL 1565
Cdd:PRK02224   261 edlrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1566 SSSCESLK---LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1642
Cdd:PRK02224   341 NEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1643 KQELYGKLRSTEANKKETEKQLQEAEQEMEE----------MKEKMRKFAKSKQQKILELEEENDRLRAEVhpagdtake 1712
Cdd:PRK02224   421 RDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV--------- 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1713 cmetllssnASMKEELERVKMEYETlSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANL-EATEKHDNQTNVTEEGTQ 1791
Cdd:PRK02224   492 ---------EEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELrERAAELEAEAEEKREAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1792 SIPGETEEqdslSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN 1871
Cdd:PRK02224   562 EAEEEAEE----AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653 1872 TLLSQIStkDGELKMLQEEvtkmnllNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQLAELN 1934
Cdd:PRK02224   638 ELEAEFD--EARIEEARED-------KERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELE 694
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1161-1702 4.27e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 4.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1161 ELEEKILALEKEKEQLQK--KLQEALTSRKAILKKAqeKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQI 1238
Cdd:COG1196    197 ELERQLEPLERQAEKAERyrELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1239 QVRESIDgklpstdqqescsstpgleeplfkateqhhtqpvlesnlcpdwpshsedasalqggtSVAQIKAQLKEIEAEK 1318
Cdd:COG1196    275 ELEELEL---------------------------------------------------------ELEEAQAEEYELLAEL 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1319 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlrelqpKLDELQ 1398
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE------ALLEAE 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1399 KLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAK 1478
Cdd:COG1196    372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1479 QQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS 1558
Cdd:COG1196    452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1559 LLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS-----------SKIAESTEWQEKHKELQKEYEILLQSYENVSN 1627
Cdd:COG1196    532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1702
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1301-2179 5.03e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 5.03e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1301 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1380
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1381 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1460
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1461 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1540
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1541 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1620
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1621 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1700
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1701 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1780
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1781 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1860
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1861 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1939
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1940 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 2019
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2020 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2099
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2100 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2179
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1059-1924 6.32e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 6.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1059 EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDAsDGDSV 1138
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL-QKELY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1139 ALVKEtvvisppctgssehwKPELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQ 1218
Cdd:TIGR02168  292 ALANE---------------ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1219 FDEQSKENENIGDQLRQLQIQVREsidgklpstDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpSHSEDasal 1298
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEE---------LEEQLETLRSKVAQLELQIASLNNEIERLEARL-----ERLED---- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1299 qggtSVAQIKAQLKEIEAEKVELELKVSSTtsELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQ 1378
Cdd:TIGR02168  415 ----RRERLQQEIEELLKKLEEAELKELQA--ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1379 LQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-------EAALtkiqtEIIEQEDLIKALHTQLE--MQAKE 1449
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAI-----EAALGGRLQAVVVENLNaaKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1450 HDERIKQLQVELCEMKQKPEeigeesrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1529
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKG---------TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1530 QNKEK-------------DTVLGRLALLQ--EERDKLITEMDRSLLENQS----LSSSCESLKLALEGLTEDKEKLVKEI 1590
Cdd:TIGR02168  635 LELAKklrpgyrivtldgDLVRPGGVITGgsAKTNSSILERRREIEELEEkieeLEEKIAELEKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1591 ESLKSSKIAESTewqeKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeQE 1670
Cdd:TIGR02168  715 EQLRKELEELSR----QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE-------AE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1671 MEEMKEKMRKFAKSKQQKILELEEENDRLRAevhpagdtakecmetLLSSNASMKEELERVKMEYETLSKKFQSLMSEKD 1750
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTL---------------LNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1751 SLSEEVQDLKHQIEGNVSKQANLE-ATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKdf 1829
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELEsELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ-- 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1830 sSHDEINNYLQQIDQLKERIAgleEEKQKNKEFSQTLENEKNTLLSQIstkDGELKMLQEEVTKMNLLNQQIQEELSRVT 1909
Cdd:TIGR02168  927 -LELRLEGLEVRIDNLQERLS---EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLAAIEEYEELK 999

                          890
                   ....*....|....*
gi 1034632653 1910 KLKETAEEEKDDLEE 1924
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTE 1014
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1433-2178 6.84e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 6.84e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1433 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1509
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfylRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1510 RGT-IERLTKSLADVESQVSAqnkekdtVLGRLALLQEERDKLITEMDR-SLLENQSLSSSCESLKLALEgltedkeklv 1587
Cdd:pfam15921  168 SNTqIEQLRKMMLSHEGVLQE-------IRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKILRELD---------- 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1588 KEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEnvsneaERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1667
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEII 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1668 EQEMEEMKEKMrkfakskQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLms 1747
Cdd:pfam15921  305 QEQARNQNSMY-------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1748 eKDSLSEEVQDL-KHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVS 1826
Cdd:pfam15921  376 -DDQLQKLLADLhKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1827 KDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM----NLLNQQIQ 1902
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1903 EELSRVTKLKETAEE---------EKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1973
Cdd:pfam15921  535 HLKNEGDHLRNVQTEcealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1974 QLVKEKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKE---KQQEVKQLQKDC----IRYQEKISALERTV 2042
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2043 KALEFVQTESQKDLEITKENL-------AQAVEHRKKAQAELASFKVLLDDTQSEaarvladnLKLKKELQSNKESVKSQ 2115
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSK--------IQFLEEAMTNANKEKHF 766

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 2116 MKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQE 2178
Cdd:pfam15921  767 LKEEKNKLSQELSTVA----TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2638-2941 9.13e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 9.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2638 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2709
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2710 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2782
Cdd:COG1196    260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2783 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2858
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2859 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2938
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                   ...
gi 1034632653 2939 RQE 2941
Cdd:COG1196    500 EAD 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-643 1.13e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 1.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653   48 EDVQERLAyaeqlvvELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:COG1196    182 EATEENLE-------RLEDILGELERQL----EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  208 QTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQ 287
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  288 RNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALE 367
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  368 QKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT----------IQQLEDQLQQKSKEISQF 437
Cdd:COG1196    491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAalaaalqnivVEDDEVAAAAIEYLKAAK 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  438 LNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRT 517
Cdd:COG1196    571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  518 GEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKE 597
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1034632653  598 MKQMEgegIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTE 643
Cdd:COG1196    731 EAERE---ELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 546-1436 1.44e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 1.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  546 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQkemkqmegegiapikmkvfledtgqdfplm 625
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS------------------------------ 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  626 pneesslpavEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHK 702
Cdd:TIGR02168  278 ----------ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  703 AQEIYE---KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaER 778
Cdd:TIGR02168  342 LEEKLEelkEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  779 QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHIS 858
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  859 SKVEELSQalsqkeleITKMDQLLLEKKRDVETLQQTIEEKdqqvteISFsmtekmvqlnEEKFSLGVEIkTLKEQLN-L 937
Cdd:TIGR02168  496 RLQENLEG--------FSEGVKALLKNQSGLSGILGVLSEL------ISV----------DEGYEAAIEA-ALGGRLQaV 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  938 LSRAEEAKKEQVEEDNEVSSG------LKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1011
Cdd:TIGR02168  551 VVENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1012 LEEELANLKDESKKEIPLSE-----TERGEVEEDKENKEYSekcVTSKCQEIEIyLKQTISEKEVELQHIRKDLEEKLAA 1086
Cdd:TIGR02168  631 LDNALELAKKLRPGYRIVTLdgdlvRPGGVITGGSAKTNSS---ILERRREIEE-LEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1087 EEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVisppctgssEHWKPELEEKI 1166
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL---------EERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1167 LALEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1243
Cdd:TIGR02168  778 AEAEAEIEELEaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES- 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1244 idgklpSTDQQEScsstpgLEEPLFKATEQHHtqpvlesnlcpdwpSHSEDASALQggTSVAQIKAQLKEIEAEKVELEL 1323
Cdd:TIGR02168  857 ------LAAEIEE------LEELIEELESELE--------------ALLNERASLE--EALALLRSELEELSEELRELES 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1324 KVSSTTSELTKKSEEVFQLQEQINKQGLEIESLK-TVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKL- 1400
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQeRLSEEYSLTLEEAEALENKIEDDEEEARrRLKRLENKIKELGPVn 988

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 1034632653 1401 ------ISKKEEDVSYLSGQLSEKEAALTKIQtEIIEQEDLI 1436
Cdd:TIGR02168  989 laaieeYEELKERYDFLTAQKEDLTEAKETLE-EAIEEIDRE 1029
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1387-1603 1.58e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.70  E-value: 1.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1387 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1466
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1467 KPEEIGEESRAKQQIQRKLQAALI----SRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLA 1542
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632653 1543 LLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1603
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PTZ00121 PTZ00121
MAEBL; Provisional
 1305-1861 1.98e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1305 AQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsHEAEVHAESLQQKLESSQLQIAGL 1384
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK--EEAKKKADAAKKKAEEKKKADEAK 1397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1385 EHLRELQPKLDELQKLIS--KKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelc 1462
Cdd:PTZ00121  1398 KKAEEDKKKADELKKAAAakKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD---- 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1463 EMKQKPEEI--GEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1540
Cdd:PTZ00121  1474 EAKKKAEEAkkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1541 LALLQEERDKLITEMDRSLLENQSLSS-SCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILL 1619
Cdd:PTZ00121  1554 AEELKKAEEKKKAEEAKKAEEDKNMALrKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1620 QSYENVSNEAERIQHvVEAVRQEKQELYGKlRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1699
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKK-AEELKKAEEENKIK-AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1700 RAEVHPAGDTAKECMETLL-SSNASMKEELERVKMEY----ETLSKKFQSLMSEKDSLSEEVQDLKHQI------EGNVS 1768
Cdd:PTZ00121  1712 AEEKKKAEELKKAEEENKIkAEEAKKEAEEDKKKAEEakkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVieeeldEEDEK 1791

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1769 KQANLEATEK--HDNQTNVTEEGTQSIP----------GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEIN 1836
Cdd:PTZ00121  1792 RRMEVDKKIKdiFDNFANIIEGGKEGNLvindskemedSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFN 1871

                          570       580
                   ....*....|....*....|....*
gi 1034632653 1837 NYLQQIDQLKERIAGLEEEKQKNKE 1861
Cdd:PTZ00121  1872 KEKDLKEDDEEEIEEADEIEKIDKD 1896
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1315-1978 2.16e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.95  E-value: 2.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1315 EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL-EHLRELQPK 1393
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1394 LDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEhderIKQLQVELCEMKQKPEEIGE 1473
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ----KEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT 1553
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1554 EMDRSLLEnqslsssCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTewQEKHKELQKEYEILLQSYENVSNEAERIQ 1633
Cdd:TIGR04523  268 QLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1634 HVVEAVRQEKQELYGKLRSTEANKKETEKqlqeaeqemeemkekmrkfaksKQQKILELEEENDRLraevhpagdtaKEC 1713
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEKQRELEE----------------------KQNEIEKLKKENQSY-----------KQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1714 METLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLeatEKHDNQTNVTEEGTQSI 1793
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL---TNQDSVKELIIKNLDNT 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1794 PGETEEQDSlsmstrpTCSESVPSAKSANPAVSKDFSSH-DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNT 1872
Cdd:TIGR04523  463 RESLETQLK-------VLSRSINKIKQNLEQKQKELKSKeKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKE 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1873 LLSQISTKDGELKMLQEEVTKMNL------LNQQIQEELSRVTKLKETAEEEKDDLEER------LMNQLAELNGSIGNY 1940
Cdd:TIGR04523  536 KESKISDLEDELNKDDFELKKENLekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKekekkdLIKEIEEKEKKISSL 615

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1034632653 1941 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1978
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
PTZ00121 PTZ00121
MAEBL; Provisional
 702-1229 2.70e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  702 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 779
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  780 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 852
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  853 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 928
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  929 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1008
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1009 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1088
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1089 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1168
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632653 1169 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1229
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-955 3.55e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.61  E-value: 3.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQkdeaLQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVlptepq 127
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLER----LRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI------ 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  128 sEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEfvmmkqqlqekeefistLQAQLs 207
Cdd:TIGR02169  243 -ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGE-----------------LEAEI- 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  208 qtqaeqaaqqvvrekdARFETQVRLHEDELLQLVTQadvETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQ 287
Cdd:TIGR02169  304 ----------------ASLERSIAEKERELEDAEER---LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  288 RNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESRYSALE 367
Cdd:TIGR02169  365 ELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN-----------ELKRELDRLQEELQRLSEELADLNAAIAGIE 433

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  368 QKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLPLQQHE 447
Cdd:TIGR02169  434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAEAEAQARASEER 505

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  448 TASQTSFPDVYNEGTQAV---TEENIASLQKRVVELENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGEAdrev 524
Cdd:TIGR02169  506 VRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGRA---- 575

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  525 SEISIVDIANKRSSSAEESGQDVLentfsqkhkELSVLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEMKQMEG 603
Cdd:TIGR02169  576 TFLPLNKMRDERRDLSILSEDGVI---------GFAVDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRMVTLEG 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  604 EGIAP---IKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQ 680
Cdd:TIGR02169  647 ELFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  681 CHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKElsmvt 760
Cdd:TIGR02169  727 QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS----- 801

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  761 ELRAQVKQLEMNLAEAERQ-RRLDYESQTAHDnllteqihslsiEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQ 839
Cdd:TIGR02169  802 KLEEEVSRIEARLREIEQKlNRLTLEKEYLEK------------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE 869

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  840 LQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEkMVQLNE 919
Cdd:TIGR02169  870 LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-DEEIPE 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1034632653  920 EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 955
Cdd:TIGR02169  949 EELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEV 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 989-1593 5.95e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  989 EQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENkeysekcvtskcqeieiyLKQTISE 1068
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEEL----EAELAELEAELEE------------------LRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1069 KEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSntdasdgdsvalvketvvis 1148
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE-------------------- 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1149 ppctgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQ----------KDDYNRLQEQ 1218
Cdd:COG1196    339 ----------LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlealraaaelAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1219 FDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASAL 1298
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL--------LEAALA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1299 QGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKK-----SEEVFQLQEQINKQGLEIE-----SLKTVSHEAEVHAE 1368
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglAGAVAVLIGVEAAYEAALEaalaaALQNIVVEDDEVAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1369 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK 1448
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1449 EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS 1528
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 1529 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQslssscESLKLALEGLTEDKEKLVKEIESL 1593
Cdd:COG1196    721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEE------LPEPPDLEELERELERLEREIEAL 779
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1580-2157 6.28e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 6.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1580 TEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIqhvvEAVRQEKQELYGKLRSTEANKKE 1659
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1660 TEKQLQEAEQEMEEMKEKM----------------RKFAKSKQQKILELEEENDRLRAEVhpagdtakECMETLLSSNAS 1723
Cdd:PRK03918   264 LEERIEELKKEIEELEEKVkelkelkekaeeyiklSEFYEEYLDELREIEKRLSRLEEEI--------NGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1724 MKEELERVKMEYETLSKKFQSLmSEKDSLSEEVQDLKHQIEGNVSKQANL---EATEKHDNQTNVTEEGTQSIPGETEEQ 1800
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITARI 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1801 DSLS--MSTRPTCSESVPSAKSANPAVSKDFSSHDE---INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN---T 1872
Cdd:PRK03918   415 GELKkeIKELKKAIEELKKAKGKCPVCGRELTEEHRkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKkesE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1873 LLSQISTKDgELKMLQEEVTKMNLlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNgsignycqdvtdaqiKNE 1952
Cdd:PRK03918   495 LIKLKELAE-QLKELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELE---------------KLE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1953 LLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIqgaqkepgnkshaKELQELLKEkQQEVKQLQKDCIRYQ 2032
Cdd:PRK03918   553 ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL-------------KELEPFYNE-YLELKDAEKELEREE 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2033 EKISALERTVKALEFVQTESQKDLEITKENLAQAveHRKKAQAELASFKVLLDDTQSEAARVLADnlklKKELQSNKESV 2112
Cdd:PRK03918   619 KELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAE----LEELEKRREEI 692

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1034632653 2113 KSQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEE 2157
Cdd:PRK03918   693 KKTLEKLKEELEEREKAKKELEKLEKalERVEELREKVKKYKALLKE 739
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1947-2688 8.46e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 8.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1947 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2026
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2027 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2106
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2107 SNKESVKSQMKQKDEdlerrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEnldstvtq 2186
Cdd:pfam02463  332 KEKEEIEELEKELKE-----LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-------- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2187 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES 2266
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2267 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2346
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2347 ADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIV 2426
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2427 LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRivgdyQQLEERHLSIILEKDQLIQEAAAENN 2506
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAES-----ELAKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2507 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDL 2586
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2587 RRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrLSALFSSSQKRIAELEEELVCVQ 2666
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK---LEKLAEEELERLEEEITKEELLQ 870

                          730       740
                   ....*....|....*....|..
gi 1034632653 2667 KEAAKKVGEIEDKLKKELKHLH 2688
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKE 892
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 322-1137 8.47e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 8.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  322 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHkaemEEKTSHILSLQKTGQELQSACDALKdq 401
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKELYALA-- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  402 nsKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQtsfpdvynEGTQAVTEENIASLQKRVVELE 481
Cdd:TIGR02168  295 --NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL--------EEKLEELKEELESLEAELEELE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  482 NEKGALLLSSIELEElkaENEKLSSQITLLEAQNRTGEADREVSEISIVDIA---NKRSSSAEESGQDVLENTFSQKHKE 558
Cdd:TIGR02168  365 AELEELESRLEELEE---QLETLRSKVAQLELQIASLNNEIERLEARLERLEdrrERLQQEIEELLKKLEEAELKELQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  559 LSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEgEGIAPIKMKVFLEDTGQDFPlmpneESSLPAVEKE 638
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFS-----EGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  639 QASTEHQSRTSEEISLnDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKsqilelELNFHKAQEIYEKNLDEKAKEI 718
Cdd:TIGR02168  516 SGLSGILGVLSELISV-DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK------QNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  719 SNLNQL--IEEFKKNADNNSSAFTALSEERDQLLSQVKelsMVTelraqvkqlemNLAEAERQRRLDYESQtahdNLLTE 796
Cdd:TIGR02168  589 NDREILknIEGFLGVAKDLVKFDPKLRKALSYLLGGVL---VVD-----------DLDNALELAKKLRPGY----RIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  797 QIHSLSIE------AKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVlegaervrhisskvEELSQALSQ 870
Cdd:TIGR02168  651 DGDLVRPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL--------------EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  871 KELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQlnllsraeEAKKEQVE 950
Cdd:TIGR02168  717 LRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA--------EAEIEELE 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  951 EDNEVSSGLKQNYDEMSpagqiskEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkdesKKEIPLS 1030
Cdd:TIGR02168  789 AQIEQLKEELKALREAL-------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL----SEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1031 ETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL---VKQMNQTLQDKTNQ 1107
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELrekLAQLELRLEGLEVR 937

                          810       820       830
                   ....*....|....*....|....*....|
gi 1034632653 1108 IDLLQAEISENQAIIQKLITSNTDASDGDS 1137
Cdd:TIGR02168  938 IDNLQERLSEEYSLTLEEAEALENKIEDDE 967
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1416-2909 1.04e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.06  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1416 SEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAAL--ISRK 1493
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELE----EENEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIknISDK 615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1494 -EALKENKSLQEELSLARGTIERLTK-SLADVESQVSAQNKEKDTVLGRLA-LLQEERDKLITEMDRSLLENQSLSssce 1570
Cdd:TIGR01612  616 nEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSkIYEDDIDALYNELSSIVKENAIDN---- 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1571 slklaleglTEDKEKLvkeiESLKSSKIAESTEWQEKHKELQKEYeilLQSYENVSNEAERIqhVVEAVRQEKQELYGKL 1650
Cdd:TIGR01612  692 ---------TEDKAKL----DDLKSKIDKEYDKIQNMETATVELH---LSNIENKKNELLDI--IVEIKKHIHGEINKDL 753

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1651 RSTEANKKETEKQLQEAEQEMEEMKEKMRKFakskQQKILELEEE-NDRLR------AEVHPAGDTAKECMETLLSSNAS 1723
Cdd:TIGR01612  754 NKILEDFKNKEKELSNKINDYAKEKDELNKY----KSKISEIKNHyNDQINidnikdEDAKQNYDKSKEYIKTISIKEDE 829

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1724 MKEELERVK-MEYETLSK-----KFQSLMSEK-DSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIpge 1796
Cdd:TIGR01612  830 IFKIINEMKfMKDDFLNKvdkfiNFENNCKEKiDSEHEQFAELTNKIKAEISDDKLNDYEKKFNDSKSLINEINKSI--- 906

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1797 teEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQ-IDQLKEriAGLEEEKQKNKeFSQTLENEKNTL-- 1873
Cdd:TIGR01612  907 --EEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKnIDTIKE--SNLIEKSYKDK-FDNTLIDKINELdk 981

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1874 ------LSQISTKDGEL----KMLQEEV--TKMNLLNQQIQEELSRVTKLketaEEEKDDLEERLMNQLAELNGSIGNYC 1941
Cdd:TIGR01612  982 afkdasLNDYEAKNNELikyfNDLKANLgkNKENMLYHQFDEKEKATNDI----EQKIEDANKNIPNIEIAIHTSIYNII 1057

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1942 QDVTDAQIKN-ELLESE-MKNLKKCVSELEEEKQQL----VKEKTKVESEIRKEYLEKIQGAQKEPGNK--SHAKELQEL 2013
Cdd:TIGR01612 1058 DEIEKEIGKNiELLNKEiLEEAEINITNFNEIKEKLkhynFDDFGKEENIKYADEINKIKDDIKNLDQKidHHIKALEEI 1137

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2014 LKEKQQEVKQLQKdciryqeKISALERTVKALefVQTESQKDLEITKENLAQAVEHRKKAQAELasfKVLLddtqSEAAR 2093
Cdd:TIGR01612 1138 KKKSENYIDEIKA-------QINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEI---KKLL----NEIAE 1201

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2094 VLADNLKLKK----ELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV--T 2165
Cdd:TIGR01612 1202 IEKDKTSLEEvkgiNLSYGKNLGKLFLEKIDEEKKKseHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETfnI 1281

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2166 LNKKDKEVQQLQENLDSTVTQLAafTKSMSSLQDD-RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkdqlrqms 2244
Cdd:TIGR01612 1282 SHDDDKDHHIISKKHDENISDIR--EKSLKIIEDFsEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANI-------- 1351

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2245 ihmeelkINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLtdl 2324
Cdd:TIGR01612 1352 -------YNILKLNKIKKIID-------------------EVKEYTKEIEENNK---NIKDELDKSEKLIKKIKDDI--- 1399

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2325 snSLEKCKEQkgnLEGIIRQQEAD--IQNSKFSYEQL---ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAI 2399
Cdd:TIGR01612 1400 --NLEECKSK---IESTLDDKDIDecIKKIKELKNHIlseESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKK 1474

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2400 AELRQQHDKEIKELENLLSQEEEENIVLEEeNKKAVDKTNQLMETLKTIKKENIQQKAQLdSFVKSMSSLQNDRDRIVgd 2479
Cdd:TIGR01612 1475 DNATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIII-- 1550

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2480 yQQLEERHLSIILE------------KDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDaeliQYREDLNQVITI 2546
Cdd:TIGR01612 1551 -KEIKDAHKKFILEaekseqkikeikKEKFrIEDDAAKNDKSNKAAIDIQLSLENFENKFLKIS----DIKKKINDCLKE 1625

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2547 KDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEdlRRSFNALQEEKQDLSKEIESLKVSISQLTRQVtalqEE 2624
Cdd:TIGR01612 1626 TESIEKKIssFSIDSQDTELKENGDNLNSLQEFLESLKDQ--KKNIEDKKKELDELDSEIEKIEIDVDQHKKNY----EI 1699

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2625 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEER 2704
Cdd:TIGR01612 1700 GIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKE 1779

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2705 ---VAELARDLVEMEQKLLMVTKENKGLTA-----QIQSFGRSMSSLQNSRDHAN----EELDELKRKYDASLKELAQLK 2772
Cdd:TIGR01612 1780 pitYDEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVNdkftKEYSKINEGFDDISKSIENVK 1859

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2773 EQ-------GLLNRERDAL---------------------LSETAFSMNSTEENS--LSHLEKLNQQLLSkdeqllHLSS 2822
Cdd:TIGR01612 1860 NStdenllfDILNKTKDAYagiigkkyysykdeaekifinISKLANSINIQIQNNsgIDLFDNINIAILS------SLDS 1933

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2823 QLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSA---------AQPSTSPAEVQSLKKAMSSLQNDRDRL 2893
Cdd:TIGR01612 1934 EKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQdtlniifenQQLYEKIQASNELKDTLSDLKYKKEKI 2013

                         1610
                   ....*....|....*.
gi 1034632653 2894 LKELKNLQQQYLQINQ 2909
Cdd:TIGR01612 2014 LNDVKLLLHKFDELNK 2029
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1306-2153 1.11e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 1.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1306 QIKAQLKEIEAEKvELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLES----SQLQI 1381
Cdd:TIGR00606  225 QITSKEAQLESSR-EIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1382 AGLEH-----LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTK-------IQTEIIEQEDLIKALHTQLEMQAKE 1449
Cdd:TIGR00606  304 NDLYHnhqrtVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqlqadrHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1450 HDERIKQLQVELCEMKQKPEEigEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESQvsa 1529
Cdd:TIGR00606  384 RGPFSERQIKNFHTLVIERQE--DEAKTAAQLCADLQSKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEE--- 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1530 qnkekdtvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALE-GLTEDKEKLVKEIESLKSSKIAESTEWQEKH 1608
Cdd:TIGR00606  456 -----------LKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKnSLTETLKKEVKSLQNEKADLDRKLRKLDQEM 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1609 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLrSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQk 1688
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLL-GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1689 ileLEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEE--LERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGN 1766
Cdd:TIGR00606  603 ---LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEEsdLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1767 VSKQANLEATEKHDNQ-TNVTEEGTQSIPGETEEQDSLSMSTRptcsesvpsaKSANPAVSKDFSSHDEINNYLQQIDQL 1845
Cdd:TIGR00606  680 CPVCQRVFQTEAELQEfISDLQSKLRLAPDKLKSTESELKKKE----------KRRDEMLGLAPGRQSIIDLKEKEIPEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1846 KERIAGLEEEKQKNKEFSQtlenEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE--------- 1916
Cdd:TIGR00606  750 RNKLQKVNRDIQRLKNDIE----EQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsdldrtvq 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1917 ------EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1990
Cdd:TIGR00606  826 qvnqekQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIK 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKEN-------- 2062
Cdd:TIGR00606  906 DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETelntvnaq 985

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2063 LAQAVEHRKKAQAELASFKVLLdDTQSEAARVLADNLKLKK---ELQSNKESVKSQMKQKDEDLERRLEQAEEKhlkekk 2139
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQDI-DTQKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQVLQMKQEHQK------ 1058

                          890
                   ....*....|....
gi 1034632653 2140 nMQEKLDALRREKV 2153
Cdd:TIGR00606 1059 -LEENIDLIKRNHV 1071
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1308-1918 1.27e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 1.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1308 KAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHL 1387
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1388 RELQPKLDELQKLISKKeedVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1467
Cdd:TIGR04523  203 LSNLKKKIQKNKSLESQ---ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1468 PEEIGEESRAKQQIQRKLQAAlisrkealkENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtvlgRLALLQEE 1547
Cdd:TIGR04523  280 NKKIKELEKQLNQLKSEISDL---------NNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNK-------IISQLNEQ 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1548 RDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKiaestewqekhkelqKEYEILLQSYENVSN 1627
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQI---------------NDLESKIQNQEKLNQ 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKIleleeendrlraevhpag 1707
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL------------------ 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1708 dtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTnvte 1787
Cdd:TIGR04523  471 -------KVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK---- 539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1788 egTQSIPGETEEQDSlsmstrptcsesvpsaksanpaVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1867
Cdd:TIGR04523  540 --ISDLEDELNKDDF----------------------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKE 595

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034632653 1868 NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEE 1918
Cdd:TIGR04523  596 KEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1295-1531 2.29e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 2.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1295 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKL 1374
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1375 ESSQLQIAGLEHlrELQPKLDELQKLISKKEEDV---SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHD 1451
Cdd:COG4942     93 AELRAELEAQKE--ELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1452 ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELslaRGTIERLTKSLADVESQVSAQN 1531
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAAAAERTPAAG 247
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1327-2258 3.28e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 3.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1327 STTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEE 1406
Cdd:TIGR00606  166 SEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYEN 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1407 DVSYLSGQLSEKEAALTKIQteiiEQEDLIKALH-TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKL 1485
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIM----KLDNEIKALKsRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1486 QAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT------------ 1553
Cdd:TIGR00606  322 VDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErqiknfhtlvie 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1554 -EMDRSLLENQSLSSSCESLKLALEGLTE--------------DKEKLVKEIESLKSSK------IAESTEWQEKHKELQ 1612
Cdd:TIGR00606  402 rQEDEAKTAAQLCADLQSKERLKQEQADEirdekkglgrtielKKEILEKKQEELKFVIkelqqlEGSSDRILELDQELR 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1613 KEYEILLQSYENVSNEAERIQhvVEAVRQEKQELYGKLRSTEanKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILEL 1692
Cdd:TIGR00606  482 KAERELSKAEKNSLTETLKKE--VKSLQNEKADLDRKLRKLD--QEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSR 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1693 EEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1772
Cdd:TIGR00606  558 HSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1773 LEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptCSESVPSAKSANPAVSKDFSSHDEINNYlqqIDQLKERIAGL 1852
Cdd:TIGR00606  638 ESDLERLKEEIEKSSKQRAMLAGATAVYSQF-------ITQLTDENQSCCPVCQRVFQTEAELQEF---ISDLQSKLRLA 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1853 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDL--EERLMNQL 1930
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEESAKVC 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1931 AELNGSIGNYCQDVTDAQIKNELLESEMK--NLKKCVSELEEEKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPG 2002
Cdd:TIGR00606  788 LTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLKSKTN 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2003 N-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAElasfk 2081
Cdd:TIGR00606  868 ElKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK----- 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2082 vlLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALrrEKVHLEETIGE 2161
Cdd:TIGR00606  943 --VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQERWLQ 1018

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2162 IQVTLNKKDKEVQQLQENLDSTVTQLAAF-TKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEI-----RLKEDNCSV 2235
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMqVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIkhfkkELREPQFRD 1098

                          970       980
                   ....*....|....*....|...
gi 1034632653 2236 LKDQLRQMSIHMEELKINISRLE 2258
Cdd:TIGR00606 1099 AEEKYREMMIVMRTTELVNKDLD 1121
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2351-3009 3.42e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 3.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2351 NSKFSYEQLETDLQaSRELTSRLHEEINMKEQKiisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEE 2430
Cdd:TIGR02169  208 EKAERYQALLKEKR-EYEGYELLKEKEALERQK---------EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2431 NKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2510
Cdd:TIGR02169  278 NKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2511 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEAnEDLRRSF 2590
Cdd:TIGR02169  358 EYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI-AGIEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2591 NALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-----GTLGLYHAQLKVKEEEVHRLSALFSSSQKR----------- 2654
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydlkEEYDRVEKELSKLQRELAEAEAQARASEERvrggraveevl 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2655 ----------IAEL------------------------EEELV---CVQKEAAKKVG----------------------- 2674
Cdd:TIGR02169  517 kasiqgvhgtVAQLgsvgeryataievaagnrlnnvvvEDDAVakeAIELLKRRKAGratflplnkmrderrdlsilsed 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2675 ----------EIEDKLKKELKHLHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLMVTKENKG- 2728
Cdd:TIGR02169  597 gvigfavdlvEFDPKYEPAFKYVFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAe 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2729 ---LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL-KEQGLLNRERDALLSETafsmnsteENSLSHLE 2804
Cdd:TIGR02169  676 lqrLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL--------EELEEDLS 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2805 KLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHlwnelEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMS 2884
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-----SRIPEIQAELSKLEEEVSRIEARLREIEQKLN 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2885 SLQNDRDRLLKELKNLQQQYL----QINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE 2960
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIdlkeQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2961 IHERRMKEQY----------LMAISDKDQQLSHLQNLIRELRSSSSQTQPL-KVQYQRQA 3009
Cdd:TIGR02169  903 RKIEELEAQIekkrkrlselKAKLEALEEELSEIEDPKGEDEEIPEEELSLeDVQAELQR 962
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1379-1654 3.69e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 52.62  E-value: 3.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1379 LQIAGLEhlRELQPKLDELQKL-----ISKKEED----VSYLSGQLSEKEAALTKIQTeIIEQEDLIKALhtQLEMQAKE 1449
Cdd:PRK05771     9 VLIVTLK--SYKDEVLEALHELgvvhiEDLKEELsnerLRKLRSLLTKLSEALDKLRS-YLPKLNPLREE--KKKVSVKS 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1450 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQaaliSRKEALKENKSLQEELSLAR---------GTI-----ER 1515
Cdd:PRK05771    84 LEELIKDVEEELEKIEKEIKELEEEISELENEIKELE----QEIERLEPWGNFDLDLSLLLgfkyvsvfvGTVpedklEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1516 LTKSLADVESQVSAQNKEKDTVLgrLALLQEERDKLITEMDRSLLENQSLSSScESLKLALEGLTEDKEKLVKEIESLKs 1595
Cdd:PRK05771   160 LKLESDVENVEYISTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESLL- 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632653 1596 SKIAESTEwqekhkelqKEYEILLQSYENVSNEAERiqhvveavrqekQELYGKLRSTE 1654
Cdd:PRK05771   236 EELKELAK---------KYLEELLALYEYLEIELER------------AEALSKFLKTD 273
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 155-425 5.44e-06

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 52.53  E-value: 5.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  155 EKEELISTLQAQLTQAQAEQPAQSSTEMEEfvMMKQQL-QEKEEF---ISTLQAQLSQTQAEQAAQQVVREKDArFETQV 230
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADKERAE--ADRQRLeQEKQQQlaaISGSQSQLESTDQNALETNGQAQRDA-ILEES 1615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  231 RLHEDELlqlvtqadveTEMQQKLRVLQRKLEEHEES-------LVGRaqVVDLLQQELTAAeqrNQILSQQL----QQM 299
Cdd:NF012221  1616 RAVTKEL----------TTLAQGLDALDSQATYAGESgdqwrnpFAGG--LLDRVQEQLDDA---KKISGKQLadakQRH 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  300 EAEHNTLRNTVetereeskillEKMELEVAErklSFHNLQEEmhhlleqfEQAG-QAQAELESRYS-ALEQKHKAEMEEK 377
Cdd:NF012221  1681 VDNQQKVKDAV-----------AKSEAGVAQ---GEQNQANA--------EQDIdDAKADAEKRKDdALAKQNEAQQAES 1738

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1034632653  378 TSHILSlqktgQELQSAcdalKDQNSKLLQDKNEQAVQSAQTIQQLED 425
Cdd:NF012221  1739 DANAAA-----NDAQSR----GEQDASAAENKANQAQADAKGAKQDES 1777
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-526 5.96e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 5.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653   47 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTvlpTEP 126
Cdd:COG1196    360 LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL---EEE 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  127 QSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQL 206
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  207 SQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLeeheeslvGRAQVVDLLQQELTAAE 286
Cdd:COG1196    517 AGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKA--------GRATFLPLDKIRARAAL 588

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  287 QRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEkmELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSAL 366
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLG--RTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGS 666

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  367 EQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQH 446
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  447 ETASQTSFPDVynegtqavTEENIASLQKRVVELENEKGAL----LLSSIELEELKAENEKLSSQI-TLLEA----QNRT 517
Cdd:COG1196    747 LLEEEALEELP--------EPPDLEELERELERLEREIEALgpvnLLAIEEYEELEERYDFLSEQReDLEEAretlEEAI 818


                   ....*....
gi 1034632653  518 GEADREVSE 526
Cdd:COG1196    819 EEIDRETRE 827
PTZ00121 PTZ00121
MAEBL; Provisional
 940-1644 6.45e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  940 RAEEAKK-EQVEEDNEVSSGLK-------QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1011
Cdd:PTZ00121  1177 KAEAARKaEEVRKAEELRKAEDarkaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK 1256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1012 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE-QF 1090
Cdd:PTZ00121  1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAaKK 1336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1091 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNtDASDGDSVALVKETVVISPPCTGSSEHWKPELEE--KILA 1168
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkKAAA 1415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1169 LEKEKEQLQKKLQEAltsRKAILKKAQEKERHLREELKQQKDDYNRLQEQfdEQSKENENIGDQLRQLQIQVRESIDGKL 1248
Cdd:PTZ00121  1416 AKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAEEAKKADEAKK 1490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1249 PSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESnlcpDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVElelkvsst 1328
Cdd:PTZ00121  1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELK-------- 1558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1329 TSELTKKSEEVFQLQEQINKQGLEIESLKTVshEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELqklisKKEEDV 1408
Cdd:PTZ00121  1559 KAEEKKKAEEAKKAEEDKNMALRKAEEAKKA--EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL-----KKAEEE 1631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1409 SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQ--RKLQ 1486
Cdd:PTZ00121  1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelKKKE 1711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1487 AALISRKEALK------------------ENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRlaLLQEER 1548
Cdd:PTZ00121  1712 AEEKKKAEELKkaeeenkikaeeakkeaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE--ELDEED 1789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1549 DKLITEMDRSLLENQSLSSSCES----LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEN 1624
Cdd:PTZ00121  1790 EKRRMEVDKKIKDIFDNFANIIEggkeGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869

                          730       740
                   ....*....|....*....|
gi 1034632653 1625 VSNEAERIQHVVEAVRQEKQ 1644
Cdd:PTZ00121  1870 FNKEKDLKEDDEEEIEEADE 1889
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1390-1935 6.66e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 6.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1390 LQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT--EIIEQ----------------EDLIKALHTQLEMQAKEHD 1451
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSqlEIIQEqarnqnsmymrqlsdlESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1452 ERIKQLQ-------VELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL----KENKSLQEELSLARGTIERLTKSL 1520
Cdd:pfam15921  342 DKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRREL 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1521 ADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE 1600
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1601 STEWQEKHK----------ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ---EA 1667
Cdd:pfam15921  502 TASLQEKERaieatnaeitKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQH 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1668 EQEMEEMKEKMRKFAKSKQQKILELEE-------ENDRLRAEVHPAGDTAKECMEtLLSSNASMKEELERVKMEYETLSK 1740
Cdd:pfam15921  582 GRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKVK-LVNAGSERLRAVKDIKQERDQLLN 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1741 KFQSLMSEKDSLSEEVQDLKHQIEGNvskqanleaTEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKS 1820
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLKRNFRNK---------SEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMG 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1821 ANPAVSKDFSSHDEINNYLQQIDQL-----KERiAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMN 1895
Cdd:pfam15921  732 MQKQITAKRGQIDALQSKIQFLEEAmtnanKEK-HFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1034632653 1896 LLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1935
Cdd:pfam15921  811 VALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2110-2792 6.77e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 6.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2110 ESVKSQMKQKDEDLERRLEQAEEKHLKEK--------------KNMQEKLDAL----RREKVHLEETIGEIQVTLNKKDK 2171
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsvidlqtklQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2172 EVQQLQENLDSTVTQLAAFTKSMSS----LQDDRDRVIDEAKKWERKFSDAIQSKEEEIRlkeDNCSVLKDQLRQMSIHM 2247
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLShegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---SLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2248 EELKINISRLEHDKQIWESKAQTEVQL----QQKVCDTLQGENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLTD 2323
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKAS---SARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2324 lSNSLEKCkeQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ-----ASRELTSRLHEEINMKE---------QKIISLLS 2389
Cdd:pfam15921  311 -QNSMYMR--QLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERDQFSQesgnlddqlQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2390 GKEEAIQ-----------------VAIAELRQQHDK---EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIK 2449
Cdd:pfam15921  388 KREKELSlekeqnkrlwdrdtgnsITIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLT 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2450 KENIQQKAQLDSFVKSMSSLQ---NDRDRIVGDYQqleerhlSIILEKDQLIQEAAAENNKLK-------EEIRGLRSHM 2519
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKmtlESSERTVSDLT-------ASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2520 DDLNSENAKLDAELIQYREDlNQVITIKDSQQKQLLEVQLQQNKELenkyAKLEEKLKESEEANEDLRRSFNALQEEKQD 2599
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEK-DKVIEILRQQIENMTQLVGQHGRTA----GAMQVEKAQLEKEINDRRLELQEFKILKDK 615

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2600 LSKEIESLKVSISQLTRQVTALQEEGTLGLyHAQLKVKEEEVHRLSALfSSSQKRIAELEEELVCVQKEAAKKVGEIE-- 2677
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMEtt 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2678 -DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2756
Cdd:pfam15921  694 tNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1034632653 2757 LKRKYDASLKELAQLKEQGLLNRERDALLSETAFSM 2792
Cdd:pfam15921  774 LSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2496-2904 7.24e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 7.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2496 QLIQEAAAENNKLKEEIRGLrshmDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELEnkyakleek 2575
Cdd:TIGR02169  146 DFISMSPVERRKIIDEIAGV----AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--------- 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2576 lkeseeanedlrrsFNALQEEKQD-----LSKEIESLKVSISQLTRQVTALqeegtlglyhaqlkvkEEEVHRLSALFSS 2650
Cdd:TIGR02169  213 --------------YQALLKEKREyegyeLLKEKEALERQKEAIERQLASL----------------EEELEKLTEEISE 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2651 SQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHhdagimrNETETAEERVAELARDLVEMEQKLLMVTKENKGLT 2730
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2731 AQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAfsmnsteENSLSHLEKLNQQL 2810
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL-------EKLKREINELKREL 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2811 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKfrksEEGKQRSAAqpstspAEVQSLKKAMSSLQNDR 2890
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK----QEWKLEQLA------ADLSKYEQELYDLKEEY 478

                          410
                   ....*....|....
gi 1034632653 2891 DRLLKELKNLQQQY 2904
Cdd:TIGR02169  479 DRVEKELSKLQREL 492
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
219-379 8.78e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 8.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  219 VREKDARFEtQVRLHEDELLQLVTQADVETEmQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQ-----RNQILS 293
Cdd:COG4913    257 IRELAERYA-AARERLAELEYLRAALRLWFA-QRRLELLEAELEELRAELARLEAELERLEARLDALREeldelEAQIRG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  294 ---QQLQQMEAEHNTL---RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQ----AGQAQAELESRY 363
Cdd:COG4913    335 nggDRLEQLEREIERLereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEeleaLEEALAEAEAAL 414

                          170
                   ....*....|....*.
gi 1034632653  364 SALEQKHKAEMEEKTS 379
Cdd:COG4913    415 RDLRRELRELEAEIAS 430
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2293-3057 9.17e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 9.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2293 LEETRHLYHSSQ---NELAKLESELK-SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2368
Cdd:pfam15921   80 LEEYSHQVKDLQrrlNESNELHEKQKfYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKC 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2369 LTSRLHEEINMKEQKIISLLSGKE---EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETl 2445
Cdd:pfam15921  160 LKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2446 KTIKKENIQQKAQLDSFVKSMSSLQNDRDRIvgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNS- 2524
Cdd:pfam15921  239 RIFPVEDQLEALKSESQNKIELLLQQHQDRI----EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSm 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2525 ---ENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2601
Cdd:pfam15921  315 ymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2602 KEIESLKVSISQLTRQVTalqeegTLGLYHAQLKVKEEEVHRLSALFSSSQKRI-AELEEELVCVQ--KEAAKKVGEIED 2678
Cdd:pfam15921  395 LEKEQNKRLWDRDTGNSI------TIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQgkNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2679 KLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSlqnsrdhANEELDELK 2758
Cdd:pfam15921  469 QL------------------ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEA-------TNAEITKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2759 RKYDASLKELAQLKEQGllnrerDALlsetafsmnsteENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAM 2838
Cdd:pfam15921  524 SRVDLKLQELQHLKNEG------DHL------------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTA 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2839 ASLQNERDHLWNELE---------KFRKSEEGKQRSAAQPSTSPAEVQSLK---------KAMSSLQNDRDRLLKELKNL 2900
Cdd:pfam15921  586 GAMQVEKAQLEKEINdrrlelqefKILKDKKDAKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTS 665

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2901 QQQYLQINQEITELHplkaqlQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE---IHERRMKEQYLMAISDK 2977
Cdd:pfam15921  666 RNELNSLSEDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAK 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2978 DQQLSHLQNLIR---ELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSN 3054
Cdd:pfam15921  740 RGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819


                   ...
gi 1034632653 3055 FSQ 3057
Cdd:pfam15921  820 FAE 822
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 237-453 9.49e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 9.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  237 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR---NTVETE 313
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  314 REESKILLEKMELEVAE--RKLSFHNLQEEMHHLL-----EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQK 386
Cdd:COG4942     92 IAELRAELEAQKEELAEllRALYRLGRQPPLALLLspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632653  387 TGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLE------DQLQQKSKEISQFLNRLPLQQHETASQTS 453
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAelaaelAELQQEAEELEALIARLEAEAAAAAERTP 244
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1302-1460 1.12e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 1.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1302 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLktvsheaevhaESLQQKLESSQLQI 1381
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEV-----------EARIKKYEEQLGNV 85

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632653 1382 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1460
Cdd:COG1579     86 RNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
702-907 1.13e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.17  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  702 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADnnssaFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQr 780
Cdd:COG3206    175 KALEFLEEQLPELRKELEEAEAALEEFRQKNG-----LVDLSEEAKLLLQQLSELeSQLAEARAELAEAEARLAALRAQ- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  781 rLDYESQTAHDNLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH---- 856
Cdd:COG3206    249 -LGSGPDALPELLQSPVIQQLRAQ-------LAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAslea 320

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653  857 ----ISSKVEELSQALSQKELEITKMDQL---LLEKKRDVETLQQTIEEKDQQVTEIS 907
Cdd:COG3206    321 eleaLQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2391-3100 1.23e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2391 KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQ 2470
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELE---KLTEEIS 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2471 NDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQ 2550
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2551 QKQLLEVQLQQNK------ELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLtrQVTALQEE 2624
Cdd:TIGR02169  342 EREIEEERKRRDKlteeyaELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL--QEELQRLS 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2625 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKelkhlhhdagiMRNETETAEER 2704
Cdd:TIGR02169  420 EELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL----EQLAADLSKYEQELYD-----------LKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2705 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRdhanEELDELKRKYDASLkELAQLKEQGLLNRERDAL 2784
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTV----AQLGSVGERYATAI-EVAAGNRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2785 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQV---QSFSKA----------MASLQNERDHLWN- 2850
Cdd:TIGR02169  560 AKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVefdPKYEPAfkyvfgdtlvVEDIEAARRLMGKy 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2851 -----ELEKFRKS------EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH---- 2915
Cdd:TIGR02169  640 rmvtlEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkig 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2916 PLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLR--MEKSSWEIHERRMK-EQYLMAISDKDQQLSH--------- 2983
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKseLKELEARIEELEEDlHKLEEALNDLEARLSHsripeiqae 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2984 LQNLIRELRSSSSQTQPLKVQYQRQASPETSASpDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKN 3063
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE-KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 1034632653 3064 TLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQEL 3100
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1831-2533 1.69e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.99  E-value: 1.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1831 SHDEINNYLQQIDQlkerIAGLEEEKQKnkefSQTLENEKNTLLSQIStkdgELKMLQEEVTKMNLlnqQIQEELSRVTK 1910
Cdd:pfam12128  219 NRQQVEHWIRDIQA----IAGIMKIRPE----FTKLQQEFNTLESAEL----RLSHLHFGYKSDET---LIASRQEERQE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1911 LKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvSELEEEKQQLVKEKTkVESEIrkEY 1990
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPS-WQSEL--EN 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL----QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2066
Cdd:pfam12128  359 LEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIagikDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2067 VEHRKKAQAELasfKVLLDDTQSEaarvladnlklkKELQSNKESVKSQMKQKDEDLERR---LEQAEEKHLKEKKNMQE 2143
Cdd:pfam12128  439 EYRLKSRLGEL---KLRLNQATAT------------PELLLQLENFDERIERAREEQEAAnaeVERLQSELRQARKRRDQ 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2144 KLDALRREKVHLEETIGEIqvtlnkkdkevQQLQENLDSTVTQLAAFTKSMSSL-QDDRDRVIDEAKKWErkfSDAIQSK 2222
Cdd:pfam12128  504 ASEALRQASRRLEERQSAL-----------DELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLHR---TDLDPEV 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2223 EEEIRLKEDNCSVLKDQLRQMSI-----HMEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETR 2297
Cdd:pfam12128  570 WDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAEEALQ----SAREKQAAAEEQLVQANGELEKASREETFAR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2298 HLYHSSQNELAKLESELKSLKDQLTD-LSNSLEKCKEQKGNLEGIIRQQEADIQNSkfsyeqletdLQASRELTSRLHEE 2376
Cdd:pfam12128  646 TALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAW----------LEEQKEQKREARTE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2377 INMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKeNIQQK 2456
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAV-RRQEV 794

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653 2457 AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKdqLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAEL 2533
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLAR--LIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 993-1870 1.71e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  993 RKLQAALinrkELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE-NKEYSEKCVTSKCQEIEIYLKQ------T 1065
Cdd:TIGR02169  170 RKKEKAL----EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQkeaierQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1066 ISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKT-NQIDLLQAEISENQAIIQKLITSNTDASDgdSVALVKET 1144
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGeEEQLRVKEKIGELEAEIASLERSIAEKER--ELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1145 VVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKE---RHLREELKQQKDDYNRLQEQFDE 1221
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDkefAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1222 QSKENENIGDQLRQLQIQVREsIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQ 1299
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELAD-LNAAIAGIEAKinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1300 GGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEE-----VFQLQEQINKQGLEIES-----LKTVSHEAEVHAES 1369
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtVAQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1370 LQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKI---QTEIIEQEDLIKALHTQLEMQ 1446
Cdd:TIGR02169  563 AIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYvfgDTLVVEDIEAARRLMGKYRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1447 AKEHDERIK---------QLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLT 1517
Cdd:TIGR02169  643 TLEGELFEKsgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1518 KSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1597
Cdd:TIGR02169  723 KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE--------------LEARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1598 IAEstEWQEKHKELQKEYEIlLQSYENVSNEAERI----QHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAeqemee 1673
Cdd:TIGR02169  789 SHS--RIPEIQAELSKLEEE-VSRIEARLREIEQKlnrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------ 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1674 mkekmrkfakskQQKILELEEENDRLRAEVhpagdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1753
Cdd:TIGR02169  860 ------------NGKKEELEEELEELEAAL-----------RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1754 EEVQDLKHQIEGNVSKQANLEATEKHDnqtnvteegtQSIPGETEEQDSLSMsTRPTCSESVPSAKSANpavskdFSSHD 1833
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGED----------EEIPEEELSLEDVQA-ELQRVEEEIRALEPVN------MLAIQ 979

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 1034632653 1834 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEK 1870
Cdd:TIGR02169  980 EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1583-2911 1.90e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 50.82  E-value: 1.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1583 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYE-------ILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTeA 1655
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEeenedsiHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1656 NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRaevhpagdtakecmetllssnASMKEELERV-KME 1734
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIY---------------------STIKSELSKIyEDD 672

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1735 YETLSKKFQSLMSEKDSLSEE----VQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1810
Cdd:TIGR01612  673 IDALYNELSSIVKENAIDNTEdkakLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKD 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1811 CSESVPSAKSANPAVSKDFSSH----DEINNYLQQIDQLKERIAG-LEEEKQKNKEFSQTLENEKNtLLSQISTKDGELK 1885
Cdd:TIGR01612  753 LNKILEDFKNKEKELSNKINDYakekDELNKYKSKISEIKNHYNDqINIDNIKDEDAKQNYDKSKE-YIKTISIKEDEIF 831

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1886 MLQEEVTKMNllnqqiQEELSRVTKLKETAEEEKDDLEERlMNQLAELNGSIGNycqdvtdaQIKNELLESEMKNLKKCV 1965
Cdd:TIGR01612  832 KIINEMKFMK------DDFLNKVDKFINFENNCKEKIDSE-HEQFAELTNKIKA--------EISDDKLNDYEKKFNDSK 896

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1966 SELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKE--LQELLKEKQQEVKQLQKDCIRYQ--------EKI 2035
Cdd:TIGR01612  897 SLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQniLKEILNKNIDTIKESNLIEKSYKdkfdntliDKI 976

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2036 SALERTVKALEFVQTESQKDLEIT-----KENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKL--KKELQSN 2108
Cdd:TIGR01612  977 NELDKAFKDASLNDYEAKNNELIKyfndlKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIaiHTSIYNI 1056

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2109 KESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvtlnKKDKEVQQLQENLDSTVTQLA 2188
Cdd:TIGR01612 1057 IDEIEKEIGKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDFGKEENI--------KYADEINKIKDDIKNLDQKID 1128

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2189 AFTKSMSSLQDDRDRVIDEAK----KWERKFSDAIQSKE-EEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQI 2263
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKaqinDLEDVADKAISNDDpEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS 1208

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2264 WESKAQTEVQLQQKVcdtlqgeNKELLSQLEEtrhlyhssqnELAKLESELKSLKDQLTDLSNSLEKCKEQKgNLEGIIR 2343
Cdd:TIGR01612 1209 LEEVKGINLSYGKNL-------GKLFLEKIDE----------EKKKSEHMIKAMEAYIEDLDEIKEKSPEIE-NEMGIEM 1270

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2344 QQEADIQNSKFSYEQLETDLQASRELTSRLhEEINMKEQKIISLLSGK------EEAIQVAIAElRQQHDKEIKELENLL 2417
Cdd:TIGR01612 1271 DIKAEMETFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEEsdindiKKELQKNLLD-AQKHNSDINLYLNEI 1348

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2418 SQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKEnIQQKAQLDSFVKSMSSLQNDRDRIVG--DYQQLEERHLSIILE 2493
Cdd:TIGR01612 1349 ANIYNILKLNKIKKiiDEVKEYTKEIEENNKNIKDE-LDKSEKLIKKIKDDINLEECKSKIEStlDDKDIDECIKKIKEL 1427

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2494 KDQLIQEAAAENNKLKEEirglrshmdDLNSENAKLDAELIQYREDLNQ-VITIKDSQQKQLLEV---QLQQNKELENKY 2569
Cdd:TIGR01612 1428 KNHILSEESNIDTYFKNA---------DENNENVLLLFKNIEMADNKSQhILKIKKDNATNDHDFninELKEHIDKSKGC 1498

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2570 AKLEEKLKESEEANEDLRRSFNalQEEKQDLSKEIE-SLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEevhrlsalf 2648
Cdd:TIGR01612 1499 KDEADKNAKAIEKNKELFEQYK--KDVTELLNKYSAlAIKNKFAKTKKDSEIIIKE--IKDAHKKFILEAE--------- 1565

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2649 sSSQKRIAELEEELVCVQKEAAK-------------KVGEIEDKLKKeLKHLHHDAGIMRNETETAEERVAELARDLVEM 2715
Cdd:TIGR01612 1566 -KSEQKIKEIKKEKFRIEDDAAKndksnkaaidiqlSLENFENKFLK-ISDIKKKINDCLKETESIEKKISSFSIDSQDT 1643

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2716 EqkllmvTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL--------------KRKYDASLKElaQLKEQGLLNRER 2781
Cdd:TIGR01612 1644 E------LKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELdseiekieidvdqhKKNYEIGIIE--KIKEIAIANKEE 1715

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2782 dalLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMAS--------------LQNERDH 2847
Cdd:TIGR01612 1716 ---IESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGcletvskepitydeIKNTRIN 1792

                         1370      1380      1390      1400      1410      1420
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 2848 LWNELEKFRKSEegKQRSAAQPSTSPAEVQSLKKAM-SSLQNDRDRLLKELKNLQQQYLQINQEI 2911
Cdd:TIGR01612 1793 AQNEFLKIIEIE--KKSKSYLDDIEAKEFDRIINHFkKKLDHVNDKFTKEYSKINEGFDDISKSI 1855
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2349-2904 2.15e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 2.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2349 IQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI--ISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQEEEENIV 2426
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLreINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELES 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2427 LEEENKKAVDKTNQLMETLKTIKKEniqqKAQLDSFVKSMSSLQNDRDRivgdYQQLEERHLSIILEKDQLIQEAAaenn 2506
Cdd:PRK03918   250 LEGSKRKLEEKIRELEERIEELKKE----IEELEEKVKELKELKEKAEE----YIKLSEFYEEYLDELREIEKRLS---- 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2507 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK----QLLEVQLQQNKELENKYAKL--EEKLKESE 2580
Cdd:PRK03918   318 RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeaKAKKEELERLKKRLTGLTPEklEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2581 EANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT----------RQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSS 2650
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2651 SQKRIAELEEEL-----VCVQKEAAKKVGEIEDKLKK-----------ELKHLHHDAGIMRNETETAE---ERVAELARD 2711
Cdd:PRK03918   478 LRKELRELEKVLkkeseLIKLKELAEQLKELEEKLKKynleelekkaeEYEKLKEKLIKLKGEIKSLKkelEKLEELKKK 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2712 LVEMEQKLLMVTKENKGLTAQIQSFGRSmsslqnSRDHANEELDELKRKYDA--SLKELAQLKEQGLLNRERDALLSETA 2789
Cdd:PRK03918   558 LAELEKKLDELEEELAELLKELEELGFE------SVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLEEELDKA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2790 FSMNSTEENSLSHLEKLNQQLLSKDEQLLHlssqlEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQP 2869
Cdd:PRK03918   632 FEELAETEKRLEELRKELEELEKKYSEEEY-----EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1034632653 2870 STSPAEVQSLKKAMSSLQNDRDRlLKELKNLQQQY 2904
Cdd:PRK03918   707 EKAKKELEKLEKALERVEELREK-VKKYKALLKER 740
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1576-2182 2.20e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 2.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1576 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEIL---LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1652
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIdkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNL 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1653 TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ------KILELEEENDRLRAEVHPAGD----------TAKECMET 1716
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKnkslesQISELKKQNNQLKDNIEKKQQeinektteisNTQTQLNQ 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1717 LLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGE 1796
Cdd:TIGR04523  258 LKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1797 TEEQDSLSmstrptcsesvpsaksanpAVSKDFSSHDEINNYLQ-QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1875
Cdd:TIGR04523  338 SQLNEQIS-------------------QLKKELTNSESENSEKQrELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1876 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAELNGSIGNYCQDVTDAQIKNELLE 1955
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLS 474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1956 SEMKNLKkcvSELEEEKQQLVKEktkvESEIRKEYLEKIQGAQKepgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKI 2035
Cdd:TIGR04523  475 RSINKIK---QNLEQKQKELKSK----EKELKKLNEEKKELEEK-------VKDLTKKISSLKEKIEKLESEKKEKESKI 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2036 SALERTVKALEFvqtesqkdlEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ 2115
Cdd:TIGR04523  541 SDLEDELNKDDF---------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653 2116 MKQKDEDLErRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2182
Cdd:TIGR04523  612 ISSLEKELE-KAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1164-1393 2.43e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1164 EKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1243
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1244 idgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTS------VAQIKAQLKEIEAE 1317
Cdd:COG4942     95 ---------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAparreqAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653 1318 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPK 1393
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
46 PHA02562
endonuclease subunit; Provisional
 1833-1993 3.14e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.63  E-value: 3.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1833 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLK 1912
Cdd:PHA02562   227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIK 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1913 E---------TAEEEKDDLEERLMNQLA-------ELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLV 1976
Cdd:PHA02562   306 DklkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQ 385

                          170
                   ....*....|....*..
gi 1034632653 1977 KEKTKVESEIRKEYLEK 1993
Cdd:PHA02562   386 DELDKIVKTKSELVKEK 402
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2238-2854 3.65e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 3.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2238 DQLRQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHlyHSSQNELAKLESELK 2315
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2316 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ-EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEA 2394
Cdd:COG4913    313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF--------AA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2395 IQVAIAELRQQHDKEIKELENLLSQEEEENivleeenKKAVDKTNQLMETLKTIKkeniQQKAQLDSFVKSM-----SSL 2469
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAAL-------RDLRRELRELEAEIASLE----RRKSNIPARLLALrdalaEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2470 QNDRD--RIVGDYQQLEERH---------------LSIILEKDQLIQEAAA-ENNKLKEEIRGLRSHMDDLNSENAKLDA 2531
Cdd:COG4913    454 GLDEAelPFVGELIEVRPEEerwrgaiervlggfaLTLLVPPEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2532 EliqyreDLNQVITIKDSQQKQLLEVQLQqnkelenkyakleeklkeseeanedlrRSFNALQEEkqdlskeieslkvSI 2611
Cdd:COG4913    534 D------SLAGKLDFKPHPFRAWLEAELG---------------------------RRFDYVCVD-------------SP 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2612 SQLTRQVTALQEEGTL-GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKkVGEIEDKLKKELKHLH-- 2688
Cdd:COG4913    568 EELRRHPRAITRAGQVkGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAE-AEERLEALEAELDALQer 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2689 HDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAqiqsfgrsmssLQNSRDHANEELDELKRKYDASLKEL 2768
Cdd:COG4913    647 REALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA-----------LEEQLEELEAELEELEEELDELKGEI 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2769 AQL-KEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLsKDEQLLHLSSQLEDSYnqvqsfskamASLQNERDH 2847
Cdd:COG4913    716 GRLeKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL-GDAVERELRENLEERI----------DALRARLNR 784


                   ....*..
gi 1034632653 2848 LWNELEK 2854
Cdd:COG4913    785 AEEELER 791
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1831-2348 3.91e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.73  E-value: 3.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1831 SHDEINNYLQQ-IDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQistkdgeLKMLQEEVTKMN-LLNQQIQEELSRV 1908
Cdd:pfam15921  254 SQNKIELLLQQhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQ-------LEIIQEQARNQNsMYMRQLSDLESTV 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1909 TKLKETAEEEKDDLEERLmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLkkcvselEEEKQQLVKEKTKVESEIRK 1988
Cdd:pfam15921  327 SQLRSELREAKRMYEDKI----EELEKQLVLANSELTEARTERDQFSQESGNL-------DDQLQKLLADLHKREKELSL 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1989 EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEV-------KQLQKDCI-RYQEKISALERTVKALEFVQTESQKdLEITK 2060
Cdd:pfam15921  396 EKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVqrleallKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQ-LESTK 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2061 ENLAQAVEHRKKAQAELASFKVLLDD--------------TQSEAARVLAD-NLKLK------------KELQSNKESVK 2113
Cdd:pfam15921  475 EMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNAEITKLRSRvDLKLQelqhlknegdhlRNVQTECEALK 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2114 SQMKQKDEDLERrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK----KDKEVQQLQEnLDSTVTQLAA 2189
Cdd:pfam15921  555 LQMAEKDKVIEI-LRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIRE-LEARVSDLEL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2190 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHME--------ELKINISRLEHDK 2261
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnklkmQLKSAQSELEQTR 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2262 QIWESKA-------------QTEVQLQQKVCDTLQGENK---ELLSQLEETRHLYHSSQNELAK---------------- 2309
Cdd:pfam15921  713 NTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQelstvateknkmagel 792

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1034632653 2310 --LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEAD 2348
Cdd:pfam15921  793 evLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1308-1516 4.04e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1308 KAQLKEIEAEKVELELKVSsttsELTKKSEEVFQLQEQINKQGLEIESLKTVShEAEVHAESLQQKLESSQLQiagLEHL 1387
Cdd:COG4913    609 RAKLAALEAELAELEEELA----EAEERLEALEAELDALQERREALQRLAEYS-WDEIDVASAEREIAELEAE---LERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1388 RELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEmKQK 1467
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLE-ERF 755

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632653 1468 PEEIGEESRakQQIQRKLQAALisrkealkenKSLQEELSLARGTIERL 1516
Cdd:COG4913    756 AAALGDAVE--RELRENLEERI----------DALRARLNRAEEELERA 792
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 919-1637 4.53e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.58  E-value: 4.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  919 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEfDLLKKENEQRKRKLQAA 998
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK-REAQEEQLKKQQLLKQL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  999 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRK 1078
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1079 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHW 1158
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1159 KPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDdynrlQEQFDEQSKENENIGDQLRQLQI 1238
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1239 QVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEK 1318
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--------DVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1319 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE----------SLQQKLESSQLQIAGLEHLR 1388
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdvrlHLQQCSQELALKLTALHALQ 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1389 ELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL--IKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1466
Cdd:TIGR00618  653 LTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGS 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1467 kpeEIGEESRAKQQIQRKLQAaliSRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1546
Cdd:TIGR00618  733 ---DLAAREDALNQSLKELMH---QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1547 ERDklitemdrsllenqslssscESLKLALEGLTEDKEKLVKEIESLKsSKIAESTEWQEKHKELQKEYEILLQSYENVS 1626
Cdd:TIGR00618  807 EIG--------------------QEIPSDEDILNLQCETLVQEEEQFL-SRLEEKSATLGEITHQLLKYEECSKQLAQLT 865

                          730
                   ....*....|.
gi 1034632653 1627 NEAERIQHVVE 1637
Cdd:TIGR00618  866 QEQAKIIQLSD 876
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 151-1015 4.66e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 4.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  151 HKLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEFVmmkQQLQEKEEFISTLQAQLSQTQAEQAAQqvVREKDARFETQV 230
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEEL-EKLTEEISELE---KRLEEIEQLLEELNKKIKDLGEEEQLR--VKEKIGELEAEI 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  231 RLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGR----AQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTL 306
Cdd:TIGR02169  304 ASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREieeeRKRRDKLTEEYAELKEELEDLRAELEEVDKEFAET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  307 RNTVETEREESKILLEKMElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQK 386
Cdd:TIGR02169  384 RDELKDYREKLEKLKREIN-----------ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  387 TGQELQSACDALKDQNSKLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAV- 465
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVh 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  466 --TEENIASLQKRVVELENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGEAdrevSEISIVDIANKRSSSAEES 543
Cdd:TIGR02169  525 gtVAQLGSVGERYATAIEVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGRA----TFLPLNKMRDERRDLSILS 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  544 GQDVLEntfsqkhkeLSVLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEMKQMEGEgiapikmkvFLEDTGqdf 622
Cdd:TIGR02169  595 EDGVIG---------FAVDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRMVTLEGE---------LFEKSG--- 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  623 pLMPNEESSLPAVEKEQASTEHQSRtseeislndagvELKSTKQDGDKSLSAVpdigqchQDELERLKSQILELELNFHK 702
Cdd:TIGR02169  654 -AMTGGSRAPRGGILFSRSEPAELQ------------RLRERLEGLKRELSSL-------QSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  703 AqeiyEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQRR 781
Cdd:TIGR02169  714 A----SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeARIEELEEDLHKLEEALNDLEARLS 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  782 LDYESQtahdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKV 861
Cdd:TIGR02169  790 HSRIPE------IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  862 EELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEekfsLGVEIKTLKEQLNLLSRA 941
Cdd:TIGR02169  864 EELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSE----LKAKLEALEEELSEIEDP 939

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653  942 EEAKKEQVEED---NEVSSGLKQNYDEMSPAGQISKEELQhEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE 1015
Cdd:TIGR02169  940 KGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAIQ-EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1824-2062 5.66e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1824 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1903
Cdd:NF012221  1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1904 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1979
Cdd:NF012221  1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1980 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2051
Cdd:NF012221  1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|.
gi 1034632653 2052 SQKDLEITKEN 2062
Cdd:NF012221  1765 AQADAKGAKQD 1775
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1384-2026 6.12e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 6.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1384 LEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDerikqlqvELCE 1463
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1464 MKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSladvesqvsaqnkekdtvlgrlal 1543
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK------------------------ 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1544 lQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLtedkEKLVKEIESLKSskiaESTEWQEKHKELQKEYEILlqsye 1623
Cdd:PRK03918   292 -AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERIKELEEKEE----RLEELKKKLKELEKRLEEL----- 357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1624 nvsneaeriqhvveavrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSK-QQKILELEEENDRLRAE 1702
Cdd:PRK03918   358 -----------------EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEiEEEISKITARIGELKKE 420

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1703 VhpagDTAKECMETLLSSNAS--------MKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1774
Cdd:PRK03918   421 I----KELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1775 ATEKHDNQTNVTEEGTQSIPGETEEQDslsmstrptcSESVPSAKSANPAVSKDFSShdeINNYLQQIDQLKERIAGLEE 1854
Cdd:PRK03918   497 KLKELAEQLKELEEKLKKYNLEELEKK----------AEEYEKLKEKLIKLKGEIKS---LKKELEKLEELKKKLAELEK 563

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1855 EKQKNKEFSQTLENEKNTL----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQL 1930
Cdd:PRK03918   564 KLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAE-TEKRL 642

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1931 AELNGSIGNYCQDVTDAQIKNelLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR--KEYLEKIQGAQKEPGNKSHAK 2008
Cdd:PRK03918   643 EELRKELEELEKKYSEEEYEE--LREEYLELSRELAGLRAELEELEKRREEIKKTLEklKEELEEREKAKKELEKLEKAL 720

                          650
                   ....*....|....*...
gi 1034632653 2009 ELQELLKEKQQEVKQLQK 2026
Cdd:PRK03918   721 ERVEELREKVKKYKALLK 738
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1766-2182 6.28e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.13  E-value: 6.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1766 NVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTC-SESVPSAKSANPAVSKDFSSHDEINNYLQQIDQ 1844
Cdd:PLN02939    41 GFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1845 LKERIAGLEEEkqknkEFSQTLEN-EKNTLLsqistkdgelkmlqeevtkMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1923
Cdd:PLN02939   121 DGEQLSDFQLE-----DLVGMIQNaEKNILL-------------------LNQARLQALEDLEKILTEKEALQGKINILE 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1924 ERLMNQLAELNGSignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEkiqgaqkepgn 2003
Cdd:PLN02939   177 MRLSETDARIKLA--------AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENML----------- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2004 kshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL----EITKENLAQAVEhrkkaqaelaS 2079
Cdd:PLN02939   238 ---LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsklsPLQYDCWWEKVE----------N 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2080 FKVLLDDTQSE---AARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHLKEKKNMQEKLDAlrre 2151
Cdd:PLN02939   305 LQDLLDRATNQvekAALVLDQNQDLRDKVDKLEASLKEANVSKFssykvELLQQKLKLLEERLQASDHEIHSYIQL---- 380

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1034632653 2152 kvhLEETIGEIQVTLNK--KDKEVQQLQENLDS 2182
Cdd:PLN02939   381 ---YQESIKEFQDTLSKlkEESKKRSLEHPADD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2007-2225 6.31e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 6.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2007 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDD 2086
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2087 TQSEAARVLADNLKLkkelqSNKESVKSQMKQKD-EDLERR---LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEI 2162
Cdd:COG4942    102 QKEELAELLRALYRL-----GRQPPLALLLSPEDfLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 2163 QVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2225
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2301-2538 7.31e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 7.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2301 HSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMK 2380
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2381 EQKIISLlsgKEEAIQVAIAELRQQHDKEIKELenLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLD 2460
Cdd:COG4942     96 RAELEAQ---KEELAELLRALYRLGRQPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653 2461 SFVKSMSSLQNDRdrivgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE 2538
Cdd:COG4942    171 AERAELEALLAEL-------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 827-1069 8.20e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 8.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  827 SEQSTLIRSLQSQ--LQNKESEVLEGAERVRHISSKVEELSQALSQ----KELEITKMDQLLLEKKRDVETLQQTIEEKD 900
Cdd:PRK05771    16 SYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKlrsyLPKLNPLREEKKKVSVKSLEELIKDVEEEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  901 QQVTEISFSMTEKMVQLNEEKFSL-------------GVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSG-----LKQN 962
Cdd:PRK05771    96 EKIEKEIKELEEEISELENEIKELeqeierlepwgnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVenveyISTD 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  963 YDEMSPAGQISKEELQHEFDLLKKENEQRKRklqaaLINRKELLQRVSRLEEELANLKDeskkeiplsetERGEVEED-- 1040
Cdd:PRK05771   176 KGYVYVVVVVLKELSDEVEEELKKLGFERLE-----LEEEGTPSELIREIKEELEEIEK-----------ERESLLEElk 239

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1034632653 1041 KENKEYSEKCVTSKC------QEIEIYLKQTISEK 1069
Cdd:PRK05771   240 ELAKKYLEELLALYEyleielERAEALSKFLKTDK 274
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2596-3189 9.56e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 9.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2596 EKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGE 2675
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELT---------AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2676 IEdKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELD 2755
Cdd:TIGR02168  304 KQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2756 ELKRKYdaslkelAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDsynqvqsfs 2835
Cdd:TIGR02168  383 TLRSKV-------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELE--------- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2836 KAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH 2915
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2916 PLKAQLQEYQ-----------------DKTKAFQImQEELRQENLSWQH--ELHQLRMEKSSWEIHERRMK-EQYLMAIS 2975
Cdd:TIGR02168  527 ELISVDEGYEaaieaalggrlqavvveNLNAAKKA-IAFLKQNELGRVTflPLDSIKGTEIQGNDREILKNiEGFLGVAK 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2976 DKDQQLSHLQNLIRELRSSSS------QTQPLKVQYQRQASPET----SASPDGSQN----------LVYETEL--LRTQ 3033
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTldgdLVRPGGVITggsaktnssiLERRREIeeLEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 3034 LNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAVSKEKgpLNID 3113
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL--EAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 3114 VAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERD---------------------QRVAA 3172
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerleslerriaaterRLEDL 843

                          650
                   ....*....|....*..
gi 1034632653 3173 ENALSVAEEQIRRLEHS 3189
Cdd:TIGR02168  844 EEQIEELSEDIESLAAE 860
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 711-905 1.05e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  711 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELS-MVTELRAQVKQLEMNLAEAERQRRLDYESQTA 789
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALArRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  790 HDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 869
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632653  870 QKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTE 905
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1940-2677 1.16e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 1.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1940 YCQDVTDAQIK----NELLESEMKNLKKCVSELEEEKQQLVKEKTKVeSEIRKEYLEKIQGAQKEPGNKSH----AKELQ 2011
Cdd:pfam15921   83 YSHQVKDLQRRlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHeleaAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2012 E-LLKEKQQEVKQLQKDCIRYQEKISALERTVkaLEFVQTESQKdleITKENLAQAVEHRKKAQAelasFKVLLDDTQSE 2090
Cdd:pfam15921  162 EdMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL--VDFEEASGKK---IYEHDSMSTMHFRSLGSA----ISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2091 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2170
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2171 KEVQQLQENLDSTVTQLaaftksMSSLQDDRDRVIDEAKKWERKFSDAiQSKEEEIRLKEDNCSV----LKDQLRQM--S 2244
Cdd:pfam15921  313 SMYMRQLSDLESTVSQL------RSELREAKRMYEDKIEELEKQLVLA-NSELTEARTERDQFSQesgnLDDQLQKLlaD 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2245 IHMEELKINISRlEHDKQIWESKAQTEVQLQ-------------QKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLE 2311
Cdd:pfam15921  386 LHKREKELSLEK-EQNKRLWDRDTGNSITIDhlrrelddrnmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS 464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2312 SELKSLKDQLTDLSNSLEKCKEQKGNLEgiirQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGK 2391
Cdd:pfam15921  465 SLTAQLESTKEMLRKVVEELTAKKMTLE----SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2392 E---------EAIQVAIAE-------LRQQhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQ 2455
Cdd:pfam15921  541 DhlrnvqtecEALKLQMAEkdkvieiLRQQ----IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKK 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2456 KAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQE---AAAENNKLKEEI----RGLRSHMDDLNSENAK 2528
Cdd:pfam15921  617 DAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTTNK 696

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2529 LDAELIQYREDLNQVITIKDSQQK---QLLEVQLQQNKELENKYAKLEEKLKESEEANEDL---RRSFNALQEEKQDLSK 2602
Cdd:pfam15921  697 LKMQLKSAQSELEQTRNTLKSMEGsdgHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMtnaNKEKHFLKEEKNKLSQ 776

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632653 2603 EIESLKVSISQLTRQVTALQEEgtlglyHAQLKVK----EEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIE 2677
Cdd:pfam15921  777 ELSTVATEKNKMAGELEVLRSQ------ERRLKEKvanmEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2285-2505 1.21e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2285 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ 2364
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2365 ASRE-LTSRLHEEINMKEQKIISLLSGKEEAIQVA-----IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2438
Cdd:COG4942    101 AQKEeLAELLRALYRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653 2439 NQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAEN 2505
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
674-1125 1.28e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  674 AVPDIGQCHQDELERLKSQILELE-LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLlsq 752
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  753 vkelsmvTELRAQVKQLEMNLAEAERQRR-LDYESQTAHDNLLT--EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 829
Cdd:PRK02224   254 -------ETLEAEIEDLRETIAETEREREeLAEEVRDLRERLEEleEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  830 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV------ 903
Cdd:PRK02224   327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvd 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  904 ----TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK----EQVEEDNEVSSGLKQNYDEmspagqisKE 975
Cdd:PRK02224   407 lgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIEEDRER--------VE 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  976 ELQHEFDLLKKENEQRKRKLQAAlINRKELLQRVSRLEEELANLKDeskkeipLSETERGEVEEDKEnkeysekcvtsKC 1055
Cdd:PRK02224   479 ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE-------LIAERRETIEEKRE-----------RA 539

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653 1056 QEieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLL------QAEISENQAIIQKL 1125
Cdd:PRK02224   540 EE----LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLerirtlLAAIADAEDEIERL 611
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1848-2384 1.30e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.15  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1848 RIAGLEEEKQKNKEFSQT-LENEKNTLLSQIS-TKDGELKMLQEEVTKMNLLNQQIQ-EELSRVTKLKETAE----EEKD 1920
Cdd:COG5022    870 YLQSAQRVELAERQLQELkIDVKSISSLKLVNlELESEIIELKKSLSSDLIENLEFKtELIARLKKLLNNIDleegPSIE 949

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1921 DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE-------SEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK--EYL 1991
Cdd:COG5022    950 YVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVregnkanSELKNFKKELAELSKQYGALQESTKQLKELPVEvaELQ 1029

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1992 EKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-KENLAQAVEHR 2070
Cdd:COG5022   1030 SASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINvKDLEVTNRNLV 1109

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2071 KKAQAE----LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDeDLERRLEQAEEKHLKEKKNMQEK-L 2145
Cdd:COG5022   1110 KPANVLqfivAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEA-NLEALPSPPPFAALSEKRLYQSAlY 1188

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2146 DALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ---SK 2222
Cdd:COG5022   1189 DEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSllnSI 1268

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2223 EEEIRLKEDNCSVLKDQLRQMSIHMEELKINisRLEHDKQIWESKAQTEVQLQQKVCDT--LQGENKEL---LSQLEETR 2297
Cdd:COG5022   1269 DNLLSSYKLEEEVLPATINSLLQYINVGLFN--ALRTKASSLRWKSATEVNYNSEELDDwcREFEISDVdeeLEELIQAV 1346

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2298 HLYHSSQNELAKLESELKSLKDQLTDLSNSLeKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEI 2377
Cdd:COG5022   1347 KVLQLLKDDLNKLDELLDACYSLNPAEIQNL-KSRYDPADKENNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIF 1425


                   ....*..
gi 1034632653 2378 NMKEQKI 2384
Cdd:COG5022   1426 SEEKSLI 1432
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
700-952 1.57e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  700 FHKAQeiyeknldeKAKEISNLNQLIEEF-------KKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 772
Cdd:COG4913    197 LHKTQ---------SFKPIGDLDDFVREYmleepdtFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  773 LAEAERQRRLD-----YESQTAHDnLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 847
Cdd:COG4913    268 RERLAELEYLRaalrlWFAQRRLE-LLEAELEELRAE-------LARLEAELERLEARLDALREELDELEAQIRGNGGDR 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  848 LEGAER--------VRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE 919
Cdd:COG4913    340 LEQLEReierlereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR 419

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1034632653  920 EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEED 952
Cdd:COG4913    420 ELRELEAEIASLERRKSNIPARLLALRDALAEA 452
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1987-2417 1.75e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1987 RKEYLEKIQGaQKEPGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERTVKALEFVQTESQKDLEITK--ENLA 2064
Cdd:COG4717     54 EADELFKPQG-RKPELNLKELKELEEELKEAEEKEEEYAEL----QEELEELEEELEELEAELEELREELEKLEklLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2065 QAVEHRKKAQAELASFKVLLDDTQSEAARVladnlklkKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2144
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2145 LDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN--------------------------------LDSTVTQLAAFTK 2192
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENEleaaaleerlkearlllliaaallallglggsLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2193 SMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDN-CSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTE 2271
Cdd:COG4717    281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2272 VQLQQKVcdtLQGENKELLSQL----EETRHLYHSSQNELAKLESELKSLKDQLTdlsnslekckEQKGNLEGIIRQQEA 2347
Cdd:COG4717    361 EELQLEE---LEQEIAALLAEAgvedEEELRAALEQAEEYQELKEELEELEEQLE----------ELLGELEELLEALDE 427

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2348 DIQNSKfsYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEeaiqvaIAELRQQHDKEIKELENLL 2417
Cdd:COG4717    428 EELEEE--LEELEEELEELEEELEELREELAELEAELEQLEEDGE------LAELLQELEELKAELRELA 489
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1468-1707 2.18e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 2.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1468 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1547
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1548 RDKLITEMDRSLLENQSLSSScESLKLALEGltEDKEKLVKEIESLKSSkiaestewQEKHKELQKEYEILLQSYENVSN 1627
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQ-PPLALLLSP--EDFLDAVRRLQYLKYL--------APARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1707
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
PTZ00121 PTZ00121
MAEBL; Provisional
 699-1243 2.19e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 2.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  699 NFHKAQEIYEKNLDEKAKEISNlnqlIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMV---TELRAQVKQLEMNLAE 775
Cdd:PTZ00121  1210 EERKAEEARKAEDAKKAEAVKK----AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFArrqAAIKAEEARKADELKK 1285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  776 AERQRRLDyESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAE 852
Cdd:PTZ00121  1286 AEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  853 RvrhisSKVEELSQALSQKELEITKMDQlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlneekfslgvEIKTLK 932
Cdd:PTZ00121  1365 K-----AEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAKK------------KADEAK 1424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  933 EQLNLLSRAEEAKKEQveEDNEVSSGLKQNYDEMSPAGQISKE-ELQHEFDLLKKENEQRKRKLQAalinrKELLQRVSR 1011
Cdd:PTZ00121  1425 KKAEEKKKADEAKKKA--EEAKKADEAKKKAEEAKKAEEAKKKaEEAKKADEAKKKAEEAKKADEA-----KKKAEEAKK 1497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1012 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQfq 1091
Cdd:PTZ00121  1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED-- 1575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1092 alvKQMNQTLQDKTNQIDllQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISppctGSSEHWKPELEEKILALEK 1171
Cdd:PTZ00121  1576 ---KNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK----AEEEKKKVEQLKKKEAEEK 1646

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632653 1172 EKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1243
Cdd:PTZ00121  1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 157-441 2.24e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.25  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  157 EELISTLQAQLTQAQAEQPAQSSTEMEefvmMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQ------- 229
Cdd:COG3096    835 EAELAALRQRRSELERELAQHRAQEQQ----LRQQLDQLKEQLQLLNKLLPQANLLADETLADRLEELREELDaaqeaqa 910

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  230 -VRLHEDELLQLVTQADVetemqqklrvLQRKLEEHEEslvgraqvvdlLQQELTAAEQRNQILSQQLQQME-----AEH 303
Cdd:COG3096    911 fIQQHGKALAQLEPLVAV----------LQSDPEQFEQ-----------LQADYLQAKEQQRRLKQQIFALSevvqrRPH 969

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  304 NTLRNTVETeREESKILLEKME--LEVAERKLSfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKtshi 381
Cdd:COG3096    970 FSYEDAVGL-LGENSDLNEKLRarLEQAEEARR--EAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQEL---- 1042

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632653  382 lslqktgQELQSACDALKDQNSKLLQDK-NEQAVQSAQTIQQLEDQLQQKSKEISQFLNRL 441
Cdd:COG3096   1043 -------EELGVQADAEAEERARIRRDElHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRL 1096
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
682-1045 2.33e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 2.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  682 HQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVT 760
Cdd:PRK02224   354 LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELrEREA 429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  761 ELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEakSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSqL 840
Cdd:PRK02224   430 ELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRERVEELEAELEDLEEEVEEVEERLERAED-L 504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  841 QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDqlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEE 920
Cdd:PRK02224   505 VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  921 KFSLGVEIKTLKEQLNLLSRAEEAKkEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFD----LLKKENEQRKRKLQ 996
Cdd:PRK02224   581 LAELKERIESLERIRTLLAAIADAE-DEIERLREKREALAELNDE-------RRERLAEKRErkreLEAEFDEARIEEAR 652

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632653  997 AALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1045
Cdd:PRK02224   653 EDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERRE 701
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1844-2175 2.65e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.66  E-value: 2.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1844 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQIST-KDGELKMLQEEVTKMNLLNQQIQEELSRVTKlketaEEEKDDL 1922
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKaRQAEMDRQAAIYAEQERMAMERERELERIRQ-----EERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1923 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepg 2002
Cdd:pfam17380  363 ERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQ------- 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2003 nkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALErtvkalefvqtesQKDLEITKENLAQAVEHRKKAQAELASFKV 2082
Cdd:pfam17380  435 -----REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKEKRDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2083 LLDDTQSEAARVLADNLK---LKKELQSNKESVKSQMKQKDEDLERRleqaEEKHLKEKKNMQEKLDALRREKVHLEETI 2159
Cdd:pfam17380  497 LEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRLEAME 572

                          330
                   ....*....|....*.
gi 1034632653 2160 GEIQVTLNKKDKEVQQ 2175
Cdd:pfam17380  573 REREMMRQIVESEKAR 588
PLN02939 PLN02939
transferase, transferring glycosyl groups
 626-993 2.99e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 2.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  626 PNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDeleRLKSQILELelNFHKAQE 705
Cdd:PLN02939    40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHN---RASMQRDEA--IAAIDNE 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  706 IYEKNLDEKakEISNLNqlIEEFKKNADNNSSAFTALSEERDQLLSQV-KELSMVTELRAQVKQLEMNLAEAERQRRLDY 784
Cdd:PLN02939   115 QQTNSKDGE--QLSDFQ--LEDLVGMIQNAEKNILLLNQARLQALEDLeKILTEKEALQGKINILEMRLSETDARIKLAA 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  785 ESQtAHDNLLTEQI----HSLSIEAKSKDVKIEVLQNELDDVQlqfsEQSTLIRSLQSQLQNKESEVLEGAERV------ 854
Cdd:PLN02939   191 QEK-IHVEILEEQLeklrNELLIRGATEGLCVHSLSKELDVLK----EENMLLKDDIQFLKAELIEVAETEERVfkleke 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  855 -RHISSKVEELSQALSQKELEITKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMT-----EKMVQLNEEKFSLGVE 927
Cdd:PLN02939   266 rSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEkVENLQDLLDRATNQVEKAALVLDqnqdlRDKVDKLEASLKEANV 345

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653  928 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFDLLKKENEQRKR 993
Cdd:PLN02939   346 SKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSL 404
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 172-1048 3.35e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 3.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  172 AEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQ 251
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  252 QKLRVLQRKLEEHEESL-VGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAE 330
Cdd:pfam02463  262 KEEEKLAQVLKENKEEEkEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  331 RKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKT--GQELQSACDALKDQNSKLLQD 408
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElkSEEEKEAQLLLELARQLEDLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  409 KNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEgtqaVTEENIASLQKRVVELENEKGALL 488
Cdd:pfam02463  422 KEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL----LKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  489 LSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKE 568
Cdd:pfam02463  498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  569 AQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQmegeGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRT 648
Cdd:pfam02463  578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLD----KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVS 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  649 SEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEF 728
Cdd:pfam02463  654 LEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  729 KKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSK 808
Cdd:pfam02463  734 INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  809 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRD 888
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  889 VETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSP 968
Cdd:pfam02463  894 KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  969 AG------QISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE 1042
Cdd:pfam02463  974 KVnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAELRLEDP 1053


                   ....*.
gi 1034632653 1043 NKEYSE 1048
Cdd:pfam02463 1054 DDPFSG 1059
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 277-514 3.48e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  277 LLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEkmELEVAERKLSfhNLQEEMHHLLEQFEQAGQAQ 356
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLK--QLAALERRIA--ALARRIRALEQELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  357 AELESRYSALEQKHKAEMEEKTSHILSLQKTGQelQSACDALkdqnskLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 436
Cdd:COG4942     86 AELEKEIAELRAELEAQKEELAELLRALYRLGR--QPPLALL------LSPEDFLDAVRRLQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653  437 FLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQ 514
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 35-616 3.58e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.65  E-value: 3.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653   35 HQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEM 114
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  115 KAQG--------------------------------GTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-LQEKEELIS 161
Cdd:pfam15921  155 EAAKclkedmledsntqieqlrkmmlshegvlqeirSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiLRELDTEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  162 TLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK-EEFISTLQAQL-----------SQTQAEQAAQQVVREKDARFETQ 229
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRiEQLISEHEVEItgltekassarSQANSIQSQLEIIQEQARNQNSM 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  230 VRLHEDELLQLVTQadVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 309
Cdd:pfam15921  315 YMRQLSDLESTVSQ--LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  310 VETEREESKILLEK-----MELEVAERKLSFHNLQ-EEMHHLLEQFEQagQAQAELESRYSALEQKHKAeMEEKTSHILS 383
Cdd:pfam15921  393 LSLEKEQNKRLWDRdtgnsITIDHLRRELDDRNMEvQRLEALLKAMKS--ECQGQMERQMAAIQGKNES-LEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  384 LQKTGQELQSACDALKDQnsKLLQDKNEQAVQS-AQTIQQLEDQLQQKSKEISQFLNRLPLQ----QHETASQTSFPDVY 458
Cdd:pfam15921  470 LESTKEMLRKVVEELTAK--KMTLESSERTVSDlTASLQEKERAIEATNAEITKLRSRVDLKlqelQHLKNEGDHLRNVQ 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  459 NE---------GTQAVTE---ENIASLQKRVVELENEKGALLLSS-----------IELEELKAENEKLSSQITLLEAQn 515
Cdd:pfam15921  548 TEcealklqmaEKDKVIEilrQQIENMTQLVGQHGRTAGAMQVEKaqlekeindrrLELQEFKILKDKKDAKIRELEAR- 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  516 rtgEADREVSEISIVDIANKRSSSAEESGQ--DVLENTFSQKHKELSVLLLEM---------KEAQEEIAFLKLQLQGKR 584
Cdd:pfam15921  627 ---VSDLELEKVKLVNAGSERLRAVKDIKQerDQLLNEVKTSRNELNSLSEDYevlkrnfrnKSEEMETTTNKLKMQLKS 703

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1034632653  585 AEEADHEVldQKEMKQMEGEGIAPIKMKVFLE 616
Cdd:pfam15921  704 AQSELEQT--RNTLKSMEGSDGHAMKVAMGMQ 733
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
973-1603 5.37e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  973 SKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkDESKKEIPLSETERGEVEEDKENKEysekcvt 1052
Cdd:PRK03918   187 RTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKLE------- 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1053 SKCQEIEIYLKQTISEKEvELQHIRKDLEEKLAAEEQFQALVKQMNQTLqDKTNQIDLLQAEISENQAIIQKLITSNTda 1132
Cdd:PRK03918   259 EKIRELEERIEELKKEIE-ELEEKVKELKELKEKAEEYIKLSEFYEEYL-DELREIEKRLSRLEEEINGIEERIKELE-- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1133 sdgdsvalvketvvisppctgSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDY 1212
Cdd:PRK03918   335 ---------------------EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1213 NRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCsstPGLEEPLfkaTEQHhtqpvlESNLCPDWPSHS 1292
Cdd:PRK03918   394 EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKC---PVCGREL---TEEH------RKELLEEYTAEL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1293 EDASAlqggtSVAQIKAQLKEIEAEKVELElKVSSTTSELTKKSEEVFQLQEQINK-QGLEIESLKTVSHEAEVHAESLQ 1371
Cdd:PRK03918   462 KRIEK-----ELKEIEEKERKLRKELRELE-KVLKKESELIKLKELAEQLKELEEKlKKYNLEELEKKAEEYEKLKEKLI 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1372 qKLESSQLQIAG-LEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEH 1450
Cdd:PRK03918   536 -KLKGEIKSLKKeLEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKEL 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1451 DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrkEALKENKSlQEELSLARGTIERLTKSLADVESQVSAQ 1530
Cdd:PRK03918   615 EREEKELKKLEEELDKAFEELAETEKRLEELRKEL--------EELEKKYS-EEEYEELREEYLELSRELAGLRAELEEL 685

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 1531 NKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1603
Cdd:PRK03918   686 EKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTE 758
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1903-2419 5.94e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 5.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1903 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELNgsignYCQDVTD---AQIKNELLESEMKNLKKCVSELEE 1970
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELE-----YLRAALRlwfAQRRLELLEAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1971 EKQQLVKEKTKVESEIR--KEYLEKIQGAQKEpgnkshakELQELLKEKQQEVKQLQKDCIRYQEKISALERTV----KA 2044
Cdd:COG4913    310 ELERLEARLDALREELDelEAQIRGNGGDRLE--------QLEREIERLERELEERERRRARLEALLAALGLPLpasaEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2045 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL- 2123
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2124 -----------ERRLEQA--------------EEKHLK------EKKNMQEKLDALR-REKVHLEET--------IGEIQ 2163
Cdd:COG4913    462 fvgelievrpeEERWRGAiervlggfaltllvPPEHYAaalrwvNRLHLRGRLVYERvRTGLPDPERprldpdslAGKLD 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2164 VTLNKKDKEVQQ-LQENLD----STVTQLAAFTKSMSSL----QDDRDRVIDEAKKWERK----FS--DAIQSKEEEIRL 2228
Cdd:COG4913    542 FKPHPFRAWLEAeLGRRFDyvcvDSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRyvlgFDnrAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2229 KEDNCSVLKDQLRQMSIHMEELKINISRLEH-DKQIWESKAQTEVQLQqkvcdtlqgenkelLSQLEETRHLYHSSQNEL 2307
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAERE--------------IAELEAELERLDASSDDL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2308 AKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE--TDLQASRELTSRLHEEINMKEQKII 2385
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlARLELRALLEERFAAALGDAVEREL 767

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1034632653 2386 SllsgkeEAIQVAIAELRQQHDKEIKELENLLSQ 2419
Cdd:COG4913    768 R------ENLEERIDALRARLNRAEEELERAMRA 795
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1161-1646 5.99e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 5.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1161 ELEEKILALEKEKEQLQK---KLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1237
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1238 IQVREsidgklpsTDQQESCSSTPGLEEPLFKATEQhhtqpvlesnlcpdwpshsedasalqggtsVAQIKAQLKEIEAE 1317
Cdd:TIGR04523  295 SEISD--------LNNQKEQDWNKELKSELKNQEKK------------------------------LEEIQNQISQNNKI 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1318 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsheaevHAESLQQKLESSQLQIaglehlRELQPKLDEL 1397
Cdd:TIGR04523  337 ISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK-------ENQSYKQEIKNLESQI------NDLESKIQNQ 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1398 QKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH---TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE 1474
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTnqdSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1475 SRAKQQ---IQRKLQAALISRKEALKEN-KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRL--ALLQEER 1548
Cdd:TIGR04523  484 LEQKQKelkSKEKELKKLNEEKKELEEKvKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkkENLEKEI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1549 DKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES---LKSSKIAESTEWQEKHKELQKEYEILLQSYENV 1625
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEkekKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643

                          490       500
                   ....*....|....*....|.
gi 1034632653 1626 SNEAERIQHVVEAVRQEKQEL 1646
Cdd:TIGR04523  644 KQEVKQIKETIKEIRNKWPEI 664
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 858-1107 6.16e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  858 SSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKFSLGVEIKTLKEQLNL 937
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  938 LSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELA 1017
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1018 NLKDESKKEiplsETERGEVEEDKENKEysekcvtskcqeieiylkQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQM 1097
Cdd:COG4942    175 ELEALLAEL----EEERAALEALKAERQ------------------KLLARLEKELAELAAELAELQQEAEELEALIARL 232

                          250
                   ....*....|
gi 1034632653 1098 NQTLQDKTNQ 1107
Cdd:COG4942    233 EAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2678-2903 6.38e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2678 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL 2757
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2758 KRKYDASLKELAQLKEQGLLNrerdALLSETAFsmnSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKA 2837
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA----LLLSPEDF---LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653 2838 MASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2903
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
PRK12704 PRK12704
phosphodiesterase; Provisional
 2069-2231 6.84e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.15  E-value: 6.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2069 HRKKAQAELASFKVLLDDTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR--LEQAEEKHLKEKKNMQEKLD 2146
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2147 ALRREKVHLEETIGEiqvtLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDD--RDRVIDEAK-KWERKFSDAIQSKE 2223
Cdd:PRK12704   104 LLEKREEELEKKEKE----LEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEeEARHEAAVLIKEIE 179


                   ....*...
gi 1034632653 2224 EEIRLKED 2231
Cdd:PRK12704   180 EEAKEEAD 187
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1307-1774 6.98e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 6.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1307 IKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKtvSHEAEVHAESLQQKLESSQlqiaglEH 1386
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQE------KK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1387 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQVELCEMKQ 1466
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1467 KPEEIGEESrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1546
Cdd:TIGR04523  399 KIQNQEKLN---QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1547 ERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKEL-QKEYEILLQSYENV 1625
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIsDLEDELNKDDFELK 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1626 SNEaeriqhvVEAVRQEKQELYGKLRSTEANKKETEKQlqeaeqemeemkekmrkfaksKQQKILELEEENDRLRAEVhp 1705
Cdd:TIGR04523  556 KEN-------LEKEIDEKNKEIEELKQTQKSLKKKQEE---------------------KQELIDQKEKEKKDLIKEI-- 605

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632653 1706 agdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1774
Cdd:TIGR04523  606 ---------EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEII 665
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1368-1597 7.03e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 7.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1368 ESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALtkIQTEIIEQEDLIKALHTQLEmqa 1447
Cdd:COG4913    238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELE--- 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1448 kEHDERIKQLQVELCEMKQKPEEIGeeSRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1527
Cdd:COG4913    313 -RLEARLDALREELDELEAQIRGNG--GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1528 SAqnkekdtvlgRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1597
Cdd:COG4913    390 AA----------LLEALEEELEALEEALAE--------------AEAALRDLRRELRELEAEIASLERRK 435
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2100-2685 7.04e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 7.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2100 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVH-------LEETIGEIQVTLNKKD 2170
Cdd:PRK03918   193 ELIKEKEKELEEVLREINEISSELPELREELEklEKEVKELEELKEEIEELEKELESlegskrkLEEKIRELEERIEELK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2171 KEVQQLQENLDStVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2250
Cdd:PRK03918   273 KEIEELEEKVKE-LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2251 KINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyHSSQNELAKLESELKSLKDQLTDLSNSLEK 2330
Cdd:PRK03918   351 EKRLEELEERHELYE-------------------EAKAKKEELERLKK--RLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2331 CKEQKGNLEGIIRQQEADIQNSKFSYEQLETdlqASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRqqhdKEI 2410
Cdd:PRK03918   410 ITARIGELKKEIKELKKAIEELKKAKGKCPV---CGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLR----KEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2411 KELENLLSqeeeeNIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQldsfvksmsslqndrdrivgDYQQLEERhlSI 2490
Cdd:PRK03918   483 RELEKVLK-----KESELIKLKELAEQLKELEEKLKKYNLEELEKKAE--------------------EYEKLKEK--LI 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2491 ILEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQyredlnqvitiKDSQQKQLLEVQLQQNKELENKY 2569
Cdd:PRK03918   536 KLKGEIKsLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE-----------LGFESVEELEERLKELEPFYNEY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2570 AKLEEKLKESeeanEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEegtlglyhaqlKVKEEEVHRLSALFS 2649
Cdd:PRK03918   605 LELKDAEKEL----EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK-----------KYSEEEYEELREEYL 669

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1034632653 2650 SSQKRIAELEEELvcvqKEAAKKVGEIE---DKLKKELK 2685
Cdd:PRK03918   670 ELSRELAGLRAEL----EELEKRREEIKktlEKLKEELE 704
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1056-1518 7.22e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 7.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1056 QEIEIYLKQTISEKEVELQHIrKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDG 1135
Cdd:COG4717     53 KEADELFKPQGRKPELNLKEL-KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1136 DSVALVKETVVISPPCtgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRL 1215
Cdd:COG4717    132 QELEALEAELAELPER-------LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1216 QEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESN---------- 1283
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlg 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1284 -LCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKS-EEVFQLQEQINKQGLEIESLKtvsH 1361
Cdd:COG4717    285 lLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELE---E 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1362 EAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEdlikalHT 1441
Cdd:COG4717    362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE------LE 435

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653 1442 QLEMQAKEHDERIKQLQVELCEMKQKPEEIgEESRAKQQIQRKLQAALISRKEALKENKSLQeelsLARGTIERLTK 1518
Cdd:COG4717    436 ELEEELEELEEELEELREELAELEAELEQL-EEDGELAELLQELEELKAELRELAEEWAALK----LALELLEEARE 507
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1305-1776 7.53e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 7.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1305 AQIKAQLKEIEAEKVELELK---VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQI 1381
Cdd:PRK03918   203 EEVLREINEISSELPELREElekLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1382 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDlikalhtqLEMQAKEHDERIKQLQVEL 1461
Cdd:PRK03918   283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE--------KEERLEELKKKLKELEKRL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1462 CEMKQKPEEIgEESRAKQQIQRKLQAALISR---------KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNK 1532
Cdd:PRK03918   355 EELEERHELY-EEAKAKKEELERLKKRLTGLtpeklekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1533 EKDT--VLGRLaLLQEERDKLITEMDRSLLE-NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE------ 1603
Cdd:PRK03918   434 AKGKcpVCGRE-LTEEHRKELLEEYTAELKRiEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKeleekl 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1604 ---WQEKHKELQKEYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677
Cdd:PRK03918   513 kkyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEkleELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1678 MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKEcMETLLSSNASMKEELERVKMEYETLSKKF-----QSLMSEKDSL 1752
Cdd:PRK03918   593 RLKELEPFYNEYLELKDAEKELEREEKELKKLEEE-LDKAFEELAETEKRLEELRKELEELEKKYseeeyEELREEYLEL 671

                          490       500
                   ....*....|....*....|....
gi 1034632653 1753 SEEVQDLKHQIEGNVSKQANLEAT 1776
Cdd:PRK03918   672 SRELAGLRAELEELEKRREEIKKT 695
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1309-1772 8.41e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 8.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1309 AQLKEIEAEKVELElkvsSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQiaglEHLR 1388
Cdd:COG4717     71 KELKELEEELKEAE----EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE----AELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1389 ELQPKLDELQ---KLISKKEEDVSYLSGQLSEKEAALTKI--QTEIIEQEDLIKAL--HTQLEMQAKEHDERIKQLQVEL 1461
Cdd:COG4717    143 ELPERLEELEerlEELRELEEELEELEAELAELQEELEELleQLSLATEEELQDLAeeLEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1462 CEMKQKPEEIGEESRAKQQIQR----KLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtv 1537
Cdd:COG4717    223 EELEEELEQLENELEAAALEERlkeaRLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK----- 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1538 lgrlALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSS-KIAESTEWQEKHKELQKEYE 1616
Cdd:COG4717    298 ----ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIA 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1617 ILLQSYeNVSNEAERIQHVVEAvrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRkfAKSKQQKILELEEEN 1696
Cdd:COG4717    374 ALLAEA-GVEDEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEEL 448

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653 1697 DRLRAEVhpagDTAKECMETLLSSN--ASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1772
Cdd:COG4717    449 EELREEL----AELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 793-1024 8.78e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 8.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  793 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 872
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  873 LEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEI----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 942
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  943 EAKKEQVEEDNEVSSGLKQNYDEMspagqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 1022
Cdd:COG4942    170 EAERAELEALLAELEEERAALEAL-------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                   ..
gi 1034632653 1023 SK 1024
Cdd:COG4942    243 TP 244
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1445-1734 9.26e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.28  E-value: 9.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1445 MQAKEHDERIKQLQVE-LCEMKQKPEE-IGEESRAKQQIQRKLQAALiSRKEAL-KENKSLQEELSLARGTIERLTKSLA 1521
Cdd:PLN02939   116 QTNSKDGEQLSDFQLEdLVGMIQNAEKnILLLNQARLQALEDLEKIL-TEKEALqGKINILEMRLSETDARIKLAAQEKI 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1522 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKE---KLVKEIESLKSS-- 1596
Cdd:PLN02939   195 HVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEErvfKLEKERSLLDASlr 274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1597 ----KIAESTEWQEKHKELQkeYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETekqlqeaeq 1669
Cdd:PLN02939   275 elesKFIVAQEDVSKLSPLQ--YDCWWEKVENLQDLLDRATNQVEkaaLVLDQNQDLRDKVDKLEASLKEA--------- 343

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 1670 emeEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKME 1734
Cdd:PLN02939   344 ---NVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2285-2662 9.56e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 9.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2285 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFS--YEQLETD 2362
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2363 LQASREL---TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD---KEIKELENLLSQEEEENIVLEEeNKKAVD 2436
Cdd:COG4717    155 LEELRELeeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELEelqQRLAELEEELEEAQEELEELEE-ELEQLE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2437 KTNQLMETLKTIKKENIQQKA------------QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAE 2504
Cdd:COG4717    234 NELEAAALEERLKEARLLLLIaaallallglggSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2505 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKElenkyakleEKLKESEEANE 2584
Cdd:COG4717    314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---------ALLAEAGVEDE 384

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653 2585 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEEL 2662
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL 462
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2100-2614 9.78e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 9.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2100 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQ 2177
Cdd:PRK02224   199 KEEKDLHERLNGLESELAELDEEIERYEEQREqaRETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2178 EnldstvtQLAAFTKSMSSLQDDRDRVIDEAKkwerkFSDA-IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISR 2256
Cdd:PRK02224   279 E-------EVRDLRERLEELEEERDDLLAEAG-----LDDAdAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAES 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2257 LEHDKQIWESKAqtevqlqqkvcDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK-------DQLTDLSNSLE 2329
Cdd:PRK02224   347 LREDADDLEERA-----------EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgdapVDLGNAEDFLE 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2330 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSrlheeinmkEQKIisllsgKEEAIQVAIAELRQQHDKE 2409
Cdd:PRK02224   416 ELREERDELREREAELEATLRTARERVEEAEALLEAGKCPEC---------GQPV------EGSPHVETIEEDRERVEEL 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2410 IKELENLLSQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH 2487
Cdd:PRK02224   481 EAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2488 LSIILEKDQLIQEAAAENNKL---KEEIRGLRSHMDDLnSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQNKE 2564
Cdd:PRK02224   561 AEAEEEAEEAREEVAELNSKLaelKERIESLERIRTLL-AAIADAEDEIERLREKREALAELND-ERRERLAEKRERKRE 638

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 2565 LENKYAKLEEKLKESEEAN-----EDLRRSFNALQEEKQDLSKEIESLKVSISQL 2614
Cdd:PRK02224   639 LEAEFDEARIEEAREDKERaeeylEQVEEKLDELREERDDLQAEIGAVENELEEL 693
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2007-2531 9.86e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 9.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2007 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERtvkalefvqtesqkdleiTKENLAQAVEHRKKAQAELASFKVLLDD 2086
Cdd:PRK02224   201 EKDLHERLNGLESELAELDEEIERYEEQREQARE------------------TRDEADEVLEEHEERREELETLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2087 TQSEAARVladnlklKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK--EKKNMQEKLDALRREKVHLEETIGEIQV 2164
Cdd:PRK02224   263 LRETIAET-------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDdaDAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2165 TLNKKDKEVQQLQENLDstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMS 2244
Cdd:PRK02224   336 AAQAHNEEAESLREDAD----DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2245 IHMEELKINISRLEhdkqiwESKAQTEVQLQQkVCDTLQgENKELLSQ---------LEETRHL--YHSSQNELAKLESE 2313
Cdd:PRK02224   412 DFLEELREERDELR------EREAELEATLRT-ARERVE-EAEALLEAgkcpecgqpVEGSPHVetIEEDRERVEELEAE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2314 LKSLKDQLTDLSNSL-------------EKCKEQKGNLEGIIRQQEADIQNSKFSYEQ-------LETDLQASRELTSRL 2373
Cdd:PRK02224   484 LEDLEEEVEEVEERLeraedlveaedriERLEERREDLEELIAERRETIEEKRERAEElreraaeLEAEAEEKREAAAEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2374 HEEINMKEQKIISLlsgkeEAIQVAIAELRQQHDKeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENI 2453
Cdd:PRK02224   564 EEEAEEAREEVAEL-----NSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653 2454 QQKAQLDSfvKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLkEEIRGLRSHMDDLNSENAKLDA 2531
Cdd:PRK02224   638 ELEAEFDE--ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-EELEELRERREALENRVEALEA 712
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1330-1762 1.01e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1330 SELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEedv 1408
Cdd:COG4717     49 ERLEKEADELFKPQGRKPELNLkELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL--- 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1409 sylsgQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQLQVELCEMKQKPEEIGEESRAkqQIQRKLQAA 1488
Cdd:COG4717    126 -----QLLPLYQELEALEAELAELPERLEELEERLE-ELRELEEELEELEAELAELQEELEELLEQLSL--ATEEELQDL 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1489 LISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDT--------VLGRLALLQEERDKLITEMDRSLL 1560
Cdd:COG4717    198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLkearllllIAAALLALLGLGGSLLSLILTIAG 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1561 ENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVR 1640
Cdd:COG4717    278 VLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1641 QEKQELygklrsteaNKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLlsS 1720
Cdd:COG4717    358 ELEEEL---------QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL--D 426

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1034632653 1721 NASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQ 1762
Cdd:COG4717    427 EEELEEELEELEEELEELEEELEELREELAELEAELEQLEED 468
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2891-3186 1.06e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2891 DRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKE-- 2968
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRErl 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2969 -----QYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdgsqnlvyETELLRTQLNDSLKEIHQ 3043
Cdd:TIGR02168  312 anlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA---------------ELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 3044 KELRIQQLNSNFSQLLEEKNTLSIQLcdtsQSLRENQQHygdllnhcavLEKQVQELQavskekgplnidvapgapQEKN 3123
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEI----ERLEARLER----------LEDRRERLQ------------------QEIE 424

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 3124 GVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRL 3186
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1816-2051 1.14e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.53  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1816 PSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK-----EFSQTLENEKNTLLSQISTKDGELKMLQEE 1890
Cdd:PRK05771    36 LKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELEKIEKEIKELEEEISELENE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1891 VTKmnllnqqIQEELSRVTKLKETAEEEKDDLEERLMNQLAelnGSI--GNYCQDVTDAQIKNELLESEMKN-------- 1960
Cdd:PRK05771   116 IKE-------LEQEIERLEPWGNFDLDLSLLLGFKYVSVFV---GTVpeDKLEELKLESDVENVEYISTDKGyvyvvvvv 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1961 LKKCVSELEEE--KQQLVKEKTKVE---SEIRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQ--- 2032
Cdd:PRK05771   186 LKELSDEVEEElkKLGFERLELEEEgtpSELIREIKEELEEIEKE------RESLLEELKELAKKYLEELLALYEYLeie 259

                          250       260
                   ....*....|....*....|
gi 1034632653 2033 -EKISALERTVKALEFVQTE 2051
Cdd:PRK05771   260 lERAEALSKFLKTDKTFAIE 279
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1576-1988 1.17e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1576 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEillqSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1655
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE----EYAELQEELEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1656 NKKETEKQLQEAEQEMEEMKEKMR-KFAKSKQQKILELEEENDRLRAEVHpagDTAKECMETLLSSNASMKEELERVKME 1734
Cdd:COG4717    124 LLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELA---ELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1735 YETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTN----------VTEEGTQSIPGETEEQDSLS 1804
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallaLLGLGGSLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1805 MSTRPTCSESVPSAKSANPAVSK----DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLEnEKNTLLSQISTK 1880
Cdd:COG4717    281 LVLGLLALLFLLLAREKASLGKEaeelQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEEL 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1881 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEM 1958
Cdd:COG4717    360 EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELeeLEEQLEELLGELEELLEALDEEELEEELEELEE 439

                          410       420       430
                   ....*....|....*....|....*....|
gi 1034632653 1959 KnlkkcVSELEEEKQQLVKEKTKVESEIRK 1988
Cdd:COG4717    440 E-----LEELEEELEELREELAELEAELEQ 464
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
683-1115 1.19e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  683 QDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADN-------NSSAFTALSEERDQLLSQVKE 755
Cdd:PRK02224   250 REELETLEAEIEDLRETIAET----EREREELAEEVRDLRERLEELEEERDDllaeaglDDADAEAVEARREELEDRDEE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  756 L-SMVTELRAQVKQLEmNLAEAERQRRLDYESQTAHdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 834
Cdd:PRK02224   326 LrDRLEECRVAAQAHN-EEAESLREDADDLEERAEE---LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  835 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKK-----RDVE--TLQQTIEEKDQQVTEis 907
Cdd:PRK02224   402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEgsPHVETIEEDRERVEE-- 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  908 fsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK--EQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 985
Cdd:PRK02224   480 ---------LEAELEDLEEEVEEVEERLERAEDLVEAEDriERLEERREDLEELIAERRETIEEKRERAEELRERAAELE 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  986 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKD--ESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLK 1063
Cdd:PRK02224   551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA 630

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 1064 QT---ISEKEVELQHIRkdLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEI 1115
Cdd:PRK02224   631 EKrerKRELEAEFDEAR--IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEI 683
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2014-2225 1.21e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2014 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2093
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2094 VLADNLKLKKELQS-------NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2166
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632653 2167 NKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2225
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
46 PHA02562
endonuclease subunit; Provisional
 1845-2134 1.33e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1845 LKERIAGLEEEkqknkefSQTLENEKNTLLSQISTKdgelKMLQEEVTKMNllNQQIQEELSRVTKLKETAEEEKDDLEE 1924
Cdd:PHA02562   172 NKDKIRELNQQ-------IQTLDMKIDHIQQQIKTY----NKNIEEQRKKN--GENIARKQNKYDELVEEAKTIKAEIEE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1925 rLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEE------KQQLVKEKTKVESeirkeylekiqgaq 1998
Cdd:PHA02562   239 -LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITK-------------- 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1999 kepgNKSHAKELQ---ELLKEKQQEVKQLqkdciryqeKISALERTVKALEFvqtesQKDLEITKENLAQAVEHRKKAQA 2075
Cdd:PHA02562   304 ----IKDKLKELQhslEKLDTAIDELEEI---------MDEFNEQSKKLLEL-----KNKISTNKQSLITLVDKAKKVKA 365

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034632653 2076 ELAsfkvllddtqseaarvladnlKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKH 2134
Cdd:PHA02562   366 AIE---------------------ELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKY 403
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2800-3088 1.63e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 1.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2800 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaevqsL 2879
Cdd:COG1196    231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR----------L 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2880 KKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhplKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSW 2959
Cdd:COG1196    301 EQDIARLEERRRELEERLEELEEELAELEEELEEL---EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2960 EIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPdgsqnlvyETELLRTQLNDSLK 3039
Cdd:COG1196    378 EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE--------EEEEEEEALEEAAE 449

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1034632653 3040 EIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLN 3088
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2443-2661 1.82e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2443 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2522
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2523 NSENAKLDAELIQ-----YREDLNQVITIKDSQQ------------KQLLEVQLQQNKELENKYAKLEEKLKESEEANED 2585
Cdd:COG4942     96 RAELEAQKEELAEllralYRLGRQPPLALLLSPEdfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653 2586 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEE 2661
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELA---------AELAELQQEAEELEALIARLEAEAAAAAER 242
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1333-1760 1.82e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 1.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1333 TKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE-SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYL 1411
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAK 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1412 SGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelcEMKQKpeeiGEESRAKQQIQRKLQAALIS 1491
Cdd:pfam15921  488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ----HLKNE----GDHLRNVQTECEALKLQMAE 559

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1492 RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLlenqslsSSCES 1571
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARV-------SDLEL 632

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1572 LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1651
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1652 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpagdtakecmeTLLSSNASMKEELERV 1731
Cdd:pfam15921  713 NTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH-----------FLKEEKNKLSQELSTV 781

                          410       420
                   ....*....|....*....|....*....
gi 1034632653 1732 KMEYETLSKKFQSLMSEKDSLSEEVQDLK 1760
Cdd:pfam15921  782 ATEKNKMAGELEVLRSQERRLKEKVANME 810
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2266-2475 1.85e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2266 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2345
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2346 EADIQ-NSKFSYEQL----ETDLQASRELtsRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQE 2420
Cdd:COG4942    110 LRALYrLGRQPPLALllspEDFLDAVRRL--QYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEE 186

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 2421 EEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDR 2475
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1493-2261 1.90e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1493 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1572
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1573 KLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1652
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1653 TEAN----KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTaKECMETLLSSNASMKEEL 1728
Cdd:pfam02463  336 EIEElekeLKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEE-LELKSEEEKEAQLLLELA 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1729 ERVKMEYETLSKK-------------FQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHdnqtNVTEEGTQSIPG 1795
Cdd:pfam02463  415 RQLEDLLKEEKKEeleileeeeesieLKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ----LVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1796 ETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1875
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1876 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLK------ETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQI 1949
Cdd:pfam02463  571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQldkatlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1950 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCI 2029
Cdd:pfam02463  651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2030 RYQEKISALERTVKALEFVQTEsqkDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK 2109
Cdd:pfam02463  731 QDKINEELKLLKQKIDEEEEEE---EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2110 ESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvTLNKKDKEVQQLQENLDSTVTQLAA 2189
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELE-----RLEEEITKEELLQELLLKEEELEEQ 882

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632653 2190 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDK 2261
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENN 954
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1062-1246 1.98e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1062 LKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL---ITSNTDASDGDSV 1138
Cdd:COG4942     32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELraeLEAQKEELAELLR 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1139 ALVKETVVISPPCTGSSEHWK-------------PELEEKILALEKEKEQLQkKLQEALTSRKAILKKAQEKERHLREEL 1205
Cdd:COG4942    112 ALYRLGRQPPLALLLSPEDFLdavrrlqylkylaPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEEERAAL 190

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1034632653 1206 KQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1246
Cdd:COG4942    191 EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1311-1778 2.33e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 2.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1311 LKEIEAEKVELElkvssttsELTKKSEEVfqlQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLREl 1390
Cdd:PRK03918   171 IKEIKRRIERLE--------KFIKRTENI---EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE- 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1391 qpKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhTQLEMQAKEH-------------------- 1450
Cdd:PRK03918   239 --EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYiklsefyeeyldelreiekr 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1451 ----DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqAALISRKEALKENKSLQEEL-----SLARGTIERLTKSLA 1521
Cdd:PRK03918   316 lsrlEEEINGIEERIKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELerlkkRLTGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1522 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqsLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIA-E 1600
Cdd:PRK03918   395 ELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEkE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1601 STEWQEKHKELQKEyeilLQSYENVSNEAERIQHVVEAVRQEKqELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK 1680
Cdd:PRK03918   468 LKEIEEKERKLRKE----LRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1681 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLK 1760
Cdd:PRK03918   543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELK 622

                          490
                   ....*....|....*...
gi 1034632653 1761 HQIEGNVSKQANLEATEK 1778
Cdd:PRK03918   623 KLEEELDKAFEELAETEK 640
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1833-2066 2.34e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1833 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKmnlLNQQIQEelsRVTKLK 1912
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAE---AEAEIEE---RREELG 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1913 ETAEEEKddLEERLMNQLAELNGSignycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEirkeyLE 1992
Cdd:COG3883     90 ERARALY--RSGGSVSYLDVLLGS-----ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK-----LA 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632653 1993 KIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2066
Cdd:COG3883    158 ELEALKAE--LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 279-1084 2.43e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  279 QQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEvaerklsfhnlQEEMHHLLEQFEQAGQAQAE 358
Cdd:pfam02463  215 LKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKE-----------EEKLAQVLKENKEEEKEKKL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  359 LESRYSALEQKHKAEMEEKTSHILSLQKTGQELQsacdALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFL 438
Cdd:pfam02463  284 QEEELKLLAKEEEELKSELLKLERRKVDDEEKLK----ESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  439 NRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTG 518
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  519 EADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEM 598
Cdd:pfam02463  440 ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDG 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  599 KQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDI 678
Cdd:pfam02463  520 VGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  679 GQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK------------AKEISNLNQLIEEFKKNADNNSSAFTALSEER 746
Cdd:pfam02463  600 DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTklkesakakesgLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  747 DQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQF 826
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  827 SEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQT-IEEKDQQVTE 905
Cdd:pfam02463  760 EEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkIKEEELEELA 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  906 ISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 985
Cdd:pfam02463  840 LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  986 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDES-KKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQ 1064
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEeEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKER 999

                          810       820
                   ....*....|....*....|
gi 1034632653 1065 TISEKEVELQHIRKDLEEKL 1084
Cdd:pfam02463 1000 LEEEKKKLIRAIIEETCQRL 1019
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2696-2923 2.46e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2696 NETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQg 2775
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2776 lLNRERDALlsetafsmnsteENSLSHLEKLNQQllsKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKF 2855
Cdd:COG4942     99 -LEAQKEEL------------AELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034632653 2856 RKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKEL----KNLQQQYLQINQEITELHPLKAQLQE 2923
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLekelAELAAELAELQQEAEELEALIARLEA 234
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1840-2079 2.52e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1840 QQIDQLKERIAGLEEE----KQKNKEFSqtLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRvtKLKETA 1915
Cdd:COG3206    182 EQLPELRKELEEAEAAleefRQKNGLVD--LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS--GPDALP 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1916 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQiknelleSEMKNLKkcvSELEEEKQQLVKEKTKVESEIRKEYLekiq 1995
Cdd:COG3206    258 ELLQSPVIQQLRAQLAELEAELAELSARYTPNH-------PDVIALR---AQIAALRAQLQQEAQRILASLEAELE---- 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1996 gaqkepGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERtvkalefvqtesqkDLEITKENLAQAVEHRKKAQA 2075
Cdd:COG3206    324 ------ALQAREASLQAQLAQLEARLAELPEL----EAELRRLER--------------EVEVARELYESLLQRLEEARL 379


                   ....
gi 1034632653 2076 ELAS 2079
Cdd:COG3206    380 AEAL 383
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
249-436 2.68e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  249 EMQQKLRVLQRKLEEH--EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMEL 326
Cdd:COG3206    186 ELRKELEEAEAALEEFrqKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVI 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  327 EVAERKLSfhNLQEEMHHLLEQF----EQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN 402
Cdd:COG3206    266 QQLRAQLA--ELEAELAELSARYtpnhPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARL 343

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632653  403 SKLLQDKNEQAV--QSAQTIQQLEDQLQQKSKEISQ 436
Cdd:COG3206    344 AELPELEAELRRleREVEVARELYESLLQRLEEARL 379
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2305-2930 2.70e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.47  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2305 NELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI 2384
Cdd:TIGR04523   40 KKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQK 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2385 ISLlsgkeeaiqvaiaelrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVK 2464
Cdd:TIGR04523  120 NKL-------------------EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2465 SMSSLQNDRDRIVGDYQQLEERhLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2544
Cdd:TIGR04523  181 EKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2545 TIKDSQQKQLLEVQLQQNKElenkyakleeklkeseeanedlrrsfnalQEEKQDLSKEIESLKVSISQLTRQvtalQEE 2624
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQN-----------------------------NKKIKELEKQLNQLKSEISDLNNQ----KEQ 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2625 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEiEDKLKKELKHLHHDAGIMRNETETAEER 2704
Cdd:TIGR04523  307 DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2705 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK-EQGLLNRERDA 2783
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKElIIKNLDNTRES 465

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2784 L---LSETAFSMNSTEENslshLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL-------- 2852
Cdd:TIGR04523  466 LetqLKVLSRSINKIKQN----LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekeskis 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2853 ---EKFRKSEEGKQRSA--AQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDK 2927
Cdd:TIGR04523  542 dleDELNKDDFELKKENleKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEK 621


                   ...
gi 1034632653 2928 TKA 2930
Cdd:TIGR04523  622 AKK 624
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 832-1235 2.82e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 2.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  832 LIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKM------DQLLLEKKRDVETLQQTIEEKDQQVTE 905
Cdd:pfam05483  364 LLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIF 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  906 ISFSMTEKMVQLNEEKFSLGV-EIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLL 984
Cdd:pfam05483  444 LLQAREKEIHDLEIQLTAIKTsEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDII 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  985 --KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYL 1062
Cdd:pfam05483  524 ncKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQI 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1063 KQTISEKEvELQHIRKDLEEKLAAEE--------QFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASd 1134
Cdd:pfam05483  604 ENKNKNIE-ELHQENKALKKKGSAENkqlnayeiKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAK- 681

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1135 gdsvALVKETVVISPPCTGSSEHwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKER---HLREELKQQKDD 1211
Cdd:pfam05483  682 ----AIADEAVKLQKEIDKRCQH---KIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSakaALEIELSNIKAE 754

                          410       420
                   ....*....|....*....|....
gi 1034632653 1212 YNRLQEQFDEQSKENENIGDQLRQ 1235
Cdd:pfam05483  755 LLSLKKQLEIEKEEKEKLKMEAKE 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2403-2620 2.95e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2403 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDY-- 2480
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELae 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2481 -----QQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdaeliqyrEDLNQVITIKDSQQKQLL 2555
Cdd:COG4942    109 llralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 2556 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTA 2620
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2107-2719 2.98e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.67  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2107 SNKESVKSQMKQKDEDLERRLEqaEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQvTLNKKDKEVQQLQENLDSTV-T 2185
Cdd:pfam12128  207 EDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLS-HLHFGYKSDETLIASRQEERqE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2186 QLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKD-----------QLRQMSIHMEELKINI 2254
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDadietaaadqeQLPSWQSELENLEERL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2255 SRLEHDKQIWESKAQTEVQLQQKVC-DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKS-LKDQLTDLSNSLEKCK 2332
Cdd:pfam12128  364 KALTGKHQDVTAKYNRRRSKIKEQNnRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREqLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2333 EQKGNLEGIIRQQEADiqnskfsyEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKE 2412
Cdd:pfam12128  444 SRLGELKLRLNQATAT--------PELLLQLENFDERIERAREEQEAANAEV--------ERLQSELRQARKRRDQASEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2413 LENLLSQEEEENIVLEEENKKAVDKTNQLMETLKtikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHL-SII 2491
Cdd:pfam12128  508 LRQASRRLEERQSALDELELQLFPQAGTLLHFLR---KEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLyGVK 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2492 LEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYredlnqvitikdsqqkqllevqlqqNKELENKYA 2570
Cdd:pfam12128  585 LDLKRIdVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQA-------------------------NGELEKASR 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2571 KLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLK----VSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLS- 2645
Cdd:pfam12128  640 EETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKdsanERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAy 719

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653 2646 --ALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDagimrnetetaEERVAELARDLVEMEQKL 2719
Cdd:pfam12128  720 wqVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVD-----------PDVIAKLKREIRTLERKI 784
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 660-1236 3.03e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 43.50  E-value: 3.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  660 ELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAqeIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAF 739
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  740 TALSE-ERDQL-LSQVKELSMVTELRAQVKQLEmNLAEAERQRRLDYESQTAH----DNLLTEQIHSLSIEAKSKDVK-- 811
Cdd:TIGR01612 1197 NEIAEiEKDKTsLEEVKGINLSYGKNLGKLFLE-KIDEEKKKSEHMIKAMEAYiedlDEIKEKSPEIENEMGIEMDIKae 1275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  812 IEVLQNELDDVQLQFSEQSTLIRSLqSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVET 891
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNI 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  892 LQ-QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLlsRAEEAKKEQVEEDNEVSsGLKQNYDEMSPAG 970
Cdd:TIGR01612 1355 LKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL--EECKSKIESTLDDKDID-ECIKKIKELKNHI 1431

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  971 QISKEELQHEFDLLKKENEQrkrklqaALINRKELLQRVSRLEEELANLKDESKKEIPLSetergeVEEDKENKEYSEKC 1050
Cdd:TIGR01612 1432 LSEESNIDTYFKNADENNEN-------VLLLFKNIEMADNKSQHILKIKKDNATNDHDFN------INELKEHIDKSKGC 1498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1051 VTskcqEIEIYLKQTISEKEVELQHiRKDLEE------KLAAEEQFQALVKQMNQTL---QDKTNQIdLLQAEISENQ-- 1119
Cdd:TIGR01612 1499 KD----EADKNAKAIEKNKELFEQY-KKDVTEllnkysALAIKNKFAKTKKDSEIIIkeiKDAHKKF-ILEAEKSEQKik 1572

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1120 AIIQKLITSNTDASDGD--SVALVKETVVISPpctgssehwkpeLEEKILALEkekeQLQKKLQEALTSRKAILKKAQEK 1197
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDksNKAAIDIQLSLEN------------FENKFLKIS----DIKKKINDCLKETESIEKKISSF 1636

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1034632653 1198 ERHLRE-ELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1236
Cdd:TIGR01612 1637 SIDSQDtELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 458-1245 3.10e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  458 YNEGTQAVTEENIASLQKRVVELENEKGALLLS----SIELEELKAENEKLSSQITLLEAQNrtGEADREVSEIsivdia 533
Cdd:TIGR02168  215 YKELKAELRELELALLVLRLEELREELEELQEElkeaEEELEELTAELQELEEKLEELRLEV--SELEEEIEEL------ 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  534 nkrsssaeesgQDVLENTfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEgiapikmkv 613
Cdd:TIGR02168  287 -----------QKELYAL-ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK--------- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  614 fLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTsEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQI 693
Cdd:TIGR02168  346 -LEELKEELESLEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  694 LELELNFHKAQ-EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 772
Cdd:TIGR02168  424 EELLKKLEEAElKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  773 LAEAERQRRLDYESQTAHDNLLTEQIH-----SLSIEA----KSKDVKIEVLQNELDDVQLQFSEQS------------- 830
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISvdegyEAAIEAalggRLQAVVVENLNAAKKAIAFLKQNELgrvtflpldsikg 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  831 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdvETLQQTIEEKDQQVTEISFSM 910
Cdd:TIGR02168  584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDGDLVRPGGVI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  911 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEdnevSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQ 990
Cdd:TIGR02168  662 TGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  991 RKRKLQAalinrkeLLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIyLKQTISEKE 1070
Cdd:TIGR02168  738 LEAEVEQ-------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA-LREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1071 VELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPP 1150
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1151 CTGSSEhwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1230
Cdd:TIGR02168  890 ALLRSE--LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967

                          810
                   ....*....|....*
gi 1034632653 1231 DQLRQLQIQVRESID 1245
Cdd:TIGR02168  968 EEARRRLKRLENKIK 982
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1957-2389 3.29e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.53  E-value: 3.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1957 EMKNLKKCVSEL--EEEKQQLVKEKTKVESEIRKEYLekIQGAQKEPGNKSHAKEL--QELLKEKQQEVKQLQKDCIRYQ 2032
Cdd:COG5022    811 EYRSYLACIIKLqkTIKREKKLRETEEVEFSLKAEVL--IQKFGRSLKAKKRFSLLkkETIYLQSAQRVELAERQLQELK 888

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2033 E---KISALERTVKALEFVQTESQKDLEitkENLAQAVEHRKKAQAELasfKVLLDDTQSEaarvladnlklkkeLQSNK 2109
Cdd:COG5022    889 IdvkSISSLKLVNLELESEIIELKKSLS---SDLIENLEFKTELIARL---KKLLNNIDLE--------------EGPSI 948

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2110 ESVKSQMKQKDEDLERRLEQAEEkhlkEKKNMQEKLDALRREkvhleetigeiqvtLNKKDKEVQQLQENLDSTVTQLAA 2189
Cdd:COG5022    949 EYVKLPELNKLHEVESKLKETSE----EYEDLLKKSTILVRE--------------GNKANSELKNFKKELAELSKQYGA 1010

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2190 FTKSMSSLQDdRDRVIDEAKKWERKFSDaiQSKEEEIRLKEDNC-SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKA 2268
Cdd:COG5022   1011 LQESTKQLKE-LPVEVAELQSASKIISS--ESTELSILKPLQKLkGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLE 1087

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2269 QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESElKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ---- 2344
Cdd:COG5022   1088 STENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEIS-KFLSQLVNTLEPVFQKLSVLQLELDGLFWEanle 1166

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1034632653 2345 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLS 2389
Cdd:COG5022   1167 ALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALFS 1211
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1161-1237 3.49e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 3.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1161 ELEEKILALEKEKEQLQKKLQEALTSRKAILKK----AQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1236
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDelaeLEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494


                   .
gi 1034632653 1237 Q 1237
Cdd:COG0542    495 A 495
PRK09039 PRK09039
peptidoglycan -binding protein;
2693-2827 3.77e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.65  E-value: 3.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2693 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK 2772
Cdd:PRK09039    43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELA 122

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034632653 2773 EQglLNRERDalLSETAfsmnsteensLSHLEKLNQQLLSKDEQLLHLSSQLEDS 2827
Cdd:PRK09039   123 QE--LDSEKQ--VSARA----------LAQVELLNQQIAALRRQLAALEAALDAS 163
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1914-2145 3.84e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 3.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1914 TAEEEKDDLEERLMN----QLAELNGSIGNYcqdvtdaqiKNELLESEMKNLKKCVSELEEEKQqlvKEKTKVESEIRKE 1989
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNE---------RLRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1990 YLEKIQGAQKEPGNKShakELQELLKEKQQEVKQLQKDCIRYQEKISALE---------------RTVKA---------- 2044
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlslllgfKYVSVfvgtvpedkl 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2045 LEFVQTESQKDLEITKEN-------LAQAVEHRKKAQAELASFKVLLDDTQSE--AARVLADNLKLKKELQSNKESVKSQ 2115
Cdd:PRK05771   158 EELKLESDVENVEYISTDkgyvyvvVVVLKELSDEVEEELKKLGFERLELEEEgtPSELIREIKEELEEIEKERESLLEE 237

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1034632653 2116 MKQKDEDLERRLEQAEEK--HLKEKKNMQEKL 2145
Cdd:PRK05771   238 LKELAKKYLEELLALYEYleIELERAEALSKF 269
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1380-1561 3.97e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 3.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1380 QIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQV 1459
Cdd:COG1579      5 DLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIK----RLELEIEEVEARIKKYEE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1460 ELcEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlg 1539
Cdd:COG1579     81 QL-GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA--- 156

                          170       180
                   ....*....|....*....|..
gi 1034632653 1540 RLALLQEERDKLITEMDRSLLE 1561
Cdd:COG1579    157 ELEELEAEREELAAKIPPELLA 178
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 689-1480 3.99e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  689 LKSQILELELNFHKAQEIYEKNLDEkAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQ 768
Cdd:TIGR00606  222 IRDQITSKEAQLESSREIVKSYENE-LDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTD 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  769 LEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV- 847
Cdd:TIGR00606  301 EQLNDLYHNHQRTVREKERELVD--CQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLe 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  848 LEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQtieekdQQVTEISFSMTEKMVQLNEEKFSLGVE 927
Cdd:TIGR00606  379 LDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQ------EQADEIRDEKKGLGRTIELKKEILEKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  928 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ--NYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINR-KE 1004
Cdd:TIGR00606  453 QEELKFVIKELQQLEGSSDRILELDQELRKAERElsKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHhTT 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1005 LLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY------LKQTISEKEVELQHIRK 1078
Cdd:TIGR00606  533 TRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTrdrlakLNKELASLEQNKNHINN 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1079 DLEEKLAAEEQFQALVKQMNQTlQDKTNQIDLLQAEIsENQAIIQKLITSNTDASDGDSVALVKETVVISPPC------T 1152
Cdd:TIGR00606  613 ELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEI-EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCqrvfqtE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1153 GSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQ 1232
Cdd:TIGR00606  691 AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1233 LRQLqiqvrESIDGKLPSTdqqESCSSTPGLEEPLFKATEQHHTQpvlesnlcpdWPSHSEDASALQGGTSVAQIKAQLK 1312
Cdd:TIGR00606  771 ETLL-----GTIMPEEESA---KVCLTDVTIMERFQMELKDVERK----------IAQQAAKLQGSDLDRTVQQVNQEKQ 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1313 EIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE-LQ 1391
Cdd:TIGR00606  833 EKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEqDS 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1392 PKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE----IIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1467
Cdd:TIGR00606  913 PLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKvkniHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKH 992

                          810
                   ....*....|...
gi 1034632653 1468 PEEIGEESRAKQQ 1480
Cdd:TIGR00606  993 QEKINEDMRLMRQ 1005
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 709-1246 4.06e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 4.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  709 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELsmvtelRAQVKQLEMNLAEAERQRrLDYESQT 788
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL------KKQKEELENELNLLEKEK-LNIQKNI 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  789 AHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL 868
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  869 SQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---------------SLGVEIKTLKE 933
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLeeiqnqisqnnkiisQLNEQISQLKK 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  934 QLNLLSRAEEAKKEQVEEDNEVSSGLK---QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 1010
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1011 RLEEELANLKDESKkeiplsetergeveeDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQF 1090
Cdd:TIGR04523  430 RLKETIIKNNSEIK---------------DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1091 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL----ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEE-- 1164
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEElk 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1165 -KILALEKEKEQLQKKLQEALTSRKAILKKAQEKERhLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1243
Cdd:TIGR04523  575 qTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEK-KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653


                   ...
gi 1034632653 1244 IDG 1246
Cdd:TIGR04523  654 IKE 656
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
276-533 4.13e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  276 DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSfhnlqeemhHLLEQFEQAGQA 355
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS---------ELESQLAEARAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  356 QAELESRYSALEQKHKAEMEEKTSHILS--LQKTGQELQSAcDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKE 433
Cdd:COG3206    235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAEL-EAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQR 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  434 ISQFLnrlplqqhetasqtsfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEklSSQITLLEA 513
Cdd:COG3206    314 ILASL---------------------EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVE--VARELYESL 370

                          250       260
                   ....*....|....*....|....
gi 1034632653  514 QNRTGEAD----REVSEISIVDIA 533
Cdd:COG3206    371 LQRLEEARlaeaLTVGNVRVIDPA 394
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2584-2994 4.15e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 4.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2584 EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhaqlkvKEEEVHRLSALFSSSQKRIAELEEELv 2663
Cdd:COG4717     84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--------------KLLQLLPLYQELEALEAELAELPERL- 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2664 cvqkeaakkvgeieDKLKKELKHLHHdagiMRNETETAEERVAELARDLVEMEQKLLMVTKEnkgltaQIQSFGRSMSSL 2743
Cdd:COG4717    149 --------------EELEERLEELRE----LEEELEELEAELAELQEELEELLEQLSLATEE------ELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2744 QNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQ 2823
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2824 LEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE--EGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2901
Cdd:COG4717    285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEEleELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2902 QQYLQINQE----------ITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYL 2971
Cdd:COG4717    365 LEELEQEIAallaeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEEL 444

                          410       420
                   ....*....|....*....|....
gi 1034632653 2972 MA-ISDKDQQLSHLQNLIRELRSS 2994
Cdd:COG4717    445 EEeLEELREELAELEAELEQLEED 468
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2283-2914 4.37e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 4.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2283 QGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLegiiRQQEADIQNSKFSYEQLETD 2362
Cdd:PRK01156   137 QGEMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKL----KSSNLELENIKKQIADDEKS 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2363 LQASRELTSRLHEEINMKEQKIISLLSGKEEAIqvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2442
Cdd:PRK01156   213 HSITLKEIERLSIEYNNAMDDYNNLKSALNELS--SLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPV 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2443 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDrdrivgdyqqleerhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2522
Cdd:PRK01156   291 YKNRNYINDYFKYKNDIENKKQILSNIDAE-------------------INKYHAIIKKLSVLQKDYNDYIKKKSRYDDL 351

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2523 NSENAKLDAELIQYREDLNQVITIKDSQQkqllevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2602
Cdd:PRK01156   352 NNQILELEGYEMDYNSYLKSIESLKKKIE--------EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2603 EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKV-----KEEEVHRLSALFSSSQKRiaeLEEELVCVQKEAAKkvgeIE 2677
Cdd:PRK01156   424 KVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVcgttlGEEKSNHIINHYNEKKSR---LEEKIREIEIEVKD----ID 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2678 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVtKENKGLTAQIQSFGRSMsslqnsrdhaneELDEL 2757
Cdd:PRK01156   497 EKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINEL-KDKHDKYEEIKNRYKSL------------KLEDL 563

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2758 KRKYDASLKELAQLKEQGLLN-----RERDALLSETAFSMNSTEENsLSHLEKLNQQLLSKDEQLLHLssqLEDSYNQVQ 2832
Cdd:PRK01156   564 DSKRTSWLNALAVISLIDIETnrsrsNEIKKQLNDLESRLQEIEIG-FPDDKSYIDKSIREIENEANN---LNNKYNEIQ 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2833 SFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT 2912
Cdd:PRK01156   640 ENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRIN 719


                   ..
gi 1034632653 2913 EL 2914
Cdd:PRK01156   720 DI 721
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1295-1488 4.41e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1295 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLeieslktvsheaevhaeslqQKL 1374
Cdd:COG4913    281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG--------------------DRL 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1375 ESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDER 1453
Cdd:COG4913    341 EQLEREIERLErELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632653 1454 IKQLQVELCEMKQKPEEIGEES-RAKQQIQRKLQAA 1488
Cdd:COG4913    421 LRELEAEIASLERRKSNIPARLlALRDALAEALGLD 456
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1303-1503 4.57e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 4.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1303 SVAQIKAQLKEIEAEKVELELKVSS--TTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1380
Cdd:COG3206    176 ALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1381 IAGLEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQ 1456
Cdd:COG3206    256 LPELLQSPVIQQLRAQLAELEAELAE----LSARYTPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREAS 331

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034632653 1457 LQVELCEMKQKPEEIGEESRAKQQIQRKLQAA------LISRKEALKENKSLQ 1503
Cdd:COG3206    332 LQAQLAQLEARLAELPELEAELRRLEREVEVArelyesLLQRLEEARLAEALT 384
PTZ00121 PTZ00121
MAEBL; Provisional
 1971-2510 4.73e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 4.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1971 EKQQLVKEKTKVESEIRKEylEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQT 2050
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2051 ESQKDLEITK----------ENLAQAVEHRKKAQA--ELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ 2118
Cdd:PTZ00121  1299 EEKKKADEAKkkaeeakkadEAKKKAEEAKKKADAakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2119 KDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEiqvTLNKKDKEVQQLQEnLDSTVTQLAAFTKSMSSLQ 2198
Cdd:PTZ00121  1379 KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD---EAKKKAEEKKKADE-AKKKAEEAKKADEAKKKAE 1454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2199 DDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiniSRLEHDKQIWESKAQTEVQLQQKV 2278
Cdd:PTZ00121  1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE----AKKKAEEAKKKADEAK---KAAEAKKKADEAKKAEEAKKADEA 1527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2279 CDTLQGENKELLSQLEETRhlyhsSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQ 2358
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKK-----KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2359 LETDLQASReltSRLHEEINMKEQKIisllsGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2438
Cdd:PTZ00121  1603 EEKKMKAEE---AKKAEEAKIKAEEL-----KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034632653 2439 NQLMETLKT--IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2510
Cdd:PTZ00121  1675 KKAEEAKKAeeDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
mukB PRK04863
chromosome partition protein MukB;
234-436 4.84e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 4.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  234 EDELLQLVTQADVETE----MQQKLRVLQRKLEEHEESL---------VGRAQVVDLLQQELTAAEQRnQILSQQLQQME 300
Cdd:PRK04863   441 EDWLEEFQAKEQEATEellsLEQKLSVAQAAHSQFEQAYqlvrkiageVSRSEAWDVARELLRRLREQ-RHLAEQLQQLR 519

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  301 AEHNTLRNTVETEREESKILLE-KMELEVAErkLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQkhkaEMEEKTS 379
Cdd:PRK04863   520 MRLSELEQRLRQQQRAERLLAEfCKRLGKNL--DDEDELEQLQEELEARLESLSESVSEARERRMALRQ----QLEQLQA 593

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034632653  380 HILSLQKTGQELQSACDALKDqnsklLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 436
Cdd:PRK04863   594 RIQRLAARAPAWLAAQDALAR-----LREQSGEEFEDSQDVTEYMQQLLERERELTV 645
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 831-1045 5.36e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  831 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 910
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  911 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNydemspagQISKEELQHEFDLLKKENE 989
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAK--------KAELEAKLAELEALKAELE 167

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034632653  990 QRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1045
Cdd:COG3883    168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2515-2717 5.46e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 5.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2515 LRSHMDDLNSENAKLDAELIQYREDLNQvitikdsqqkqlLEVQLQQNKElENKYAKLEEKLKESEEANEDLRRSFNALQ 2594
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEE------------AEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEAR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2595 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVG 2674
Cdd:COG3206    233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1034632653 2675 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2717
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
402-527 5.63e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 5.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  402 NSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLplQQHETASQTSFPDVynegtqavteeNIASLQKRVVELE 481
Cdd:COG4913    608 NRAKLAALEAELAELEEELAEAEERLEALEAELDALQERR--EALQRLAEYSWDEI-----------DVASAEREIAELE 674

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1034632653  482 NEKGALLLSSIELEELKAENEKLSSQITllEAQNRTGEADREVSEI 527
Cdd:COG4913    675 AELERLDASSDDLAALEEQLEELEAELE--ELEEELDELKGEIGRL 718
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1451-1703 5.67e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 5.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1451 DERIKQLQ----VELCEMKQkpEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGT-----IERLTKSLA 1521
Cdd:PRK05771    19 DEVLEALHelgvVHIEDLKE--ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKsleelIKDVEEELE 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1522 DVESQVSAQNKEkdtvlgrLALLQEERDKLITEMDR-SLLENQSLS----SSCESLKLALEGLTEDKEKLVKEIESLKSS 1596
Cdd:PRK05771    97 KIEKEIKELEEE-------ISELENEIKELEQEIERlEPWGNFDLDlsllLGFKYVSVFVGTVPEDKLEELKLESDVENV 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1597 KIAESTEwqEK-------HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrstEANKKETEKQLqeaeq 1669
Cdd:PRK05771   170 EYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL-------EEIEKERESLL----- 235

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1034632653 1670 emeemkEKMRKFAKSKQQKILELEE--ENDRLRAEV 1703
Cdd:PRK05771   236 ------EELKELAKKYLEELLALYEylEIELERAEA 265
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2220-2980 5.87e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 5.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2220 QSKEEEIRLKEDNCSVLKDQLRQMsihmEELKINISRLEHDKQIWESkaqTEVQLQQKVCDTLQGENKELLSQLEETRHL 2299
Cdd:TIGR00606  234 ESSREIVKSYENELDPLKNRLKEI----EHNLSKIMKLDNEIKALKS---RKKQMEKDNSELELKMEKVFQGTDEQLNDL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2300 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEgiIRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEEINM 2379
Cdd:TIGR00606  307 YHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL--VEQGRLQLQADRHQEHIRARDSLI---QSLATRLELDG 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2380 KEQKIISllsgkEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2459
Cdd:TIGR00606  382 FERGPFS-----ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2460 DSFVKSMSSLQNDRDRIVGDYQQL--EERHLSIiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE----- 2532
Cdd:TIGR00606  457 KFVIKELQQLEGSSDRILELDQELrkAERELSK-AEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrt 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2533 ----LIQYREDLNQVITIKDSQQKQLLEVQL---QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIE 2605
Cdd:TIGR00606  536 qmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2606 SLKVSISQLTRQV----TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKeAAKKVGEIEDKLK 2681
Cdd:TIGR00606  616 SKEEQLSSYEDKLfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCP-VCQRVFQTEAELQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2682 KELKHLHHDAGIMRNETETAEERVAELARD------LVEMEQKLL-MVTKENKGLTAQIQSFGRSMSSLQNSRDHANEEL 2754
Cdd:TIGR00606  695 EFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlgLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2755 D------ELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEEnslshLEKLNQQLLSKDEQLLHLSSQLEDSY 2828
Cdd:TIGR00606  775 GtimpeeESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRT-----VQQVNQEKQEKQHELDTVVSKIELNR 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2829 NQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-I 2907
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEElI 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2908 NQEITELHPLKAQLQEYQDKTKA--------FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQ 2979
Cdd:TIGR00606  930 SSKETSNKKAQDKVNDIKEKVKNihgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDT 1009


                   .
gi 1034632653 2980 Q 2980
Cdd:TIGR00606 1010 Q 1010
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1058-1237 5.99e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 5.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1058 IEIYLKQTISEK-----------EVELQHIRKDLEEKLAAEEQFQA---------LVKQMNQTLQDKTNQIDLLQAEISE 1117
Cdd:COG3206    158 AEAYLEQNLELRreearkaleflEEQLPELRKELEEAEAALEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1118 NQAIIQKLitSNTDASDGDSVALVKETVVISppctgssehwkpELEEKILALEKEKEQ--------------LQKKLQEA 1183
Cdd:COG3206    238 AEARLAAL--RAQLGSGPDALPELLQSPVIQ------------QLRAQLAELEAELAElsarytpnhpdviaLRAQIAAL 303

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1034632653 1184 LTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1237
Cdd:COG3206    304 RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
46 PHA02562
endonuclease subunit; Provisional
 2538-2774 6.16e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 6.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2538 EDL--NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQD----LSKEIESLKVSI 2611
Cdd:PHA02562   157 EDLldISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKTIKAEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2612 SQLTRQVTALQEEGtlGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVC------------VQKEAAKKVGEIEDK 2679
Cdd:PHA02562   237 EELTDELLNLVMDI--EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCptctqqisegpdRITKIKDKLKELQHS 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2680 LKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQsfgrsmsSLQNSRDHANEELDELKR 2759
Cdd:PHA02562   315 LEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQD 386

                          250
                   ....*....|....*
gi 1034632653 2760 KYDASLKELAQLKEQ 2774
Cdd:PHA02562   387 ELDKIVKTKSELVKE 401
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2037-2206 6.81e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 6.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2037 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2112
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2113 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2169
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1034632653 2170 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2206
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 694-1408 6.89e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.35  E-value: 6.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  694 LELELNFHKAQEIYEKnLDEKAKEISNLNQLIEEFKKNADNNSSAFTA----LSEERDQLLSQVKElSMVTELRAQVKQL 769
Cdd:TIGR01612 1005 LKANLGKNKENMLYHQ-FDEKEKATNDIEQKIEDANKNIPNIEIAIHTsiynIIDEIEKEIGKNIE-LLNKEILEEAEIN 1082

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  770 EMNLAE-AERQRRLDYESQTAHDNL-LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 847
Cdd:TIGR01612 1083 ITNFNEiKEKLKHYNFDDFGKEENIkYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA 1162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  848 LEGaERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdVETLQQTIEEkdqqVTEISFSMTEKM-----VQLNEEKF 922
Cdd:TIGR01612 1163 ISN-DDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAE-IEKDKTSLEE----VKGINLSYGKNLgklflEKIDEEKK 1236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  923 SLGVEIKTLKEQLNLLsraEEAKKEQVEEDNEVSSGLKQNyDEMSPAgQISKEELQHEFDLLKKENEQRKRKLQAALinr 1002
Cdd:TIGR01612 1237 KSEHMIKAMEAYIEDL---DEIKEKSPEIENEMGIEMDIK-AEMETF-NISHDDDKDHHIISKKHDENISDIREKSL--- 1308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1003 kELLQRVSRlEEELANLKDESKKEIplsetergeVEEDKENkeysekcvtskcQEIEIYLKQTISEKEV-ELQHIRKDLE 1081
Cdd:TIGR01612 1309 -KIIEDFSE-ESDINDIKKELQKNL---------LDAQKHN------------SDINLYLNEIANIYNIlKLNKIKKIID 1365

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1082 EKlaaeEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAI--IQKLITSNTDASDGDSV---ALVKETVVISPPcTGSSE 1156
Cdd:TIGR01612 1366 EV----KEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeCKSKIESTLDDKDIDECikkIKELKNHILSEE-SNIDT 1440

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1157 HWK--PELEEKILALEKEKEQLQKKLQEALTSRKailKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLR 1234
Cdd:TIGR01612 1441 YFKnaDENNENVLLLFKNIEMADNKSQHILKIKK---DNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFE 1517

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1235 QLQIQVRESIDgKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLES-------NLCPDWPSHSEDASALQGGTSVAQI 1307
Cdd:TIGR01612 1518 QYKKDVTELLN-KYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAekseqkiKEIKKEKFRIEDDAAKNDKSNKAAI 1596

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1308 KAQLKEIEAEKVELELkvssttSELTKKSEEVFQLQEQINKQ--GLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE 1385
Cdd:TIGR01612 1597 DIQLSLENFENKFLKI------SDIKKKINDCLKETESIEKKisSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIE 1670

                          730       740
                   ....*....|....*....|...
gi 1034632653 1386 hlrELQPKLDELQKLISKKEEDV 1408
Cdd:TIGR01612 1671 ---DKKKELDELDSEIEKIEIDV 1690
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 242-921 7.37e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.34  E-value: 7.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  242 TQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNtlrntvetereesKILL 321
Cdd:TIGR00606  409 TAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSD-------------RILE 475

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  322 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELqSACDALKDQ 401
Cdd:TIGR00606  476 LDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKM-DKDEQIRKI 554

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  402 NSKLLQDKNEQAVQSAQTiQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEE---------NIAS 472
Cdd:TIGR00606  555 KSRHSDELTSLLGYFPNK-KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQlssyedklfDVCG 633

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  473 LQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQN--------RTGEADREVSEIsIVDIANKRSSSAEEsg 544
Cdd:TIGR00606  634 SQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENqsccpvcqRVFQTEAELQEF-ISDLQSKLRLAPDK-- 710

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  545 QDVLENTFSQKHKELSVLLL-------EMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLED 617
Cdd:TIGR00606  711 LKSTESELKKKEKRRDEMLGlapgrqsIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTD 790

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  618 TGqdfpLMPNEESSLPAVEKEqasTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIG--------------QCHQ 683
Cdd:TIGR00606  791 VT----IMERFQMELKDVERK---IAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIelnrkliqdqqeqiQHLK 863

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  684 DELERLKSQILELELNFHKAQEiYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELR 763
Cdd:TIGR00606  864 SKTNELKSEKLQIGTNLQRRQQ-FEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK 942

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  764 AQ---------------------------VKQLEMNLA-----------------EAERQRRLDYESQTAHDNLLTEQIH 799
Cdd:TIGR00606  943 VNdikekvknihgymkdienkiqdgkddyLKQKETELNtvnaqleecekhqekinEDMRLMRQDIDTQKIQERWLQDNLT 1022

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  800 SLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKmd 879
Cdd:TIGR00606 1023 LRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE-- 1100

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1034632653  880 qlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 921
Cdd:TIGR00606 1101 ----EKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMK 1138
46 PHA02562
endonuclease subunit; Provisional
 2431-2676 7.62e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 7.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2431 NKKAVDKTNQLMETLkTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2510
Cdd:PHA02562   172 NKDKIRELNQQIQTL-DMKIDHIQQ--QIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVM 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2511 EIRGLRSHMDDLNSENAKLDAELIQYREDlnqvitIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSF 2590
Cdd:PHA02562   249 DIEDPSAALNKLNTAAAKIKSKIEQFQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAI 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2591 NALQE---EKQDLSKEIESLKVSISQLTRQVTAlqeegtlglYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2667
Cdd:PHA02562   323 DELEEimdEFNEQSKKLLELKNKISTNKQSLIT---------LVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK 393


                   ....*....
gi 1034632653 2668 EAAKKVGEI 2676
Cdd:PHA02562   394 TKSELVKEK 402
PRK12704 PRK12704
phosphodiesterase; Provisional
 222-363 7.84e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 7.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  222 KDARFETQVRLHE------DELLQLVTQADVE-TEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQ 294
Cdd:PRK12704    45 EEAKKEAEAIKKEalleakEEIHKLRNEFEKElRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQ 124

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034632653  295 QLQQMEAEHNTLRNTVETE--------REESK-ILLEKMELEvaerklsfhnLQEEMHHLLEQFEQAGQAQAELESRY 363
Cdd:PRK12704   125 ELEKKEEELEELIEEQLQElerisgltAEEAKeILLEKVEEE----------ARHEAAVLIKEIEEEAKEEADKKAKE 192
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1840-1993 7.95e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 7.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1840 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKE------ 1913
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1914 ---TAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1990
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1034632653 1991 LEK 1993
Cdd:COG1579    177 LAL 179
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1847-2383 8.06e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 8.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1847 ERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1926
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1927 MNQLAELNGsignycqdvtdAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSH 2006
Cdd:pfam01576   85 EEEEERSQQ-----------LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2007 AKELQEL-------LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAS 2079
Cdd:pfam01576  154 RKLLEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAE 233

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2080 FKVLLDDTQSEAARVLA---DNLKLKKELQSNKESVKSQMKQKDEDLERRlEQAEEKHLKEKKNMQEKLDALRREKVHLE 2156
Cdd:pfam01576  234 LRAQLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2157 ETIGEIQVTLNKKDKEVQQLQENLDSTV----TQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEE-------E 2225
Cdd:pfam01576  313 DTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqaE 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2226 IRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE---SKAQTEVQ-------LQQKVCDTLQGENKELLSQLEE 2295
Cdd:pfam01576  393 LRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELEsvssllnEAEGKNIKLSKDVSSLESQLQD 472

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2296 TRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE 2375
Cdd:pfam01576  473 TQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQR 552


                   ....*...
gi 1034632653 2376 EINMKEQK 2383
Cdd:pfam01576  553 ELEALTQQ 560
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
811-1214 8.08e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 8.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  811 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELS--QALSQKELEITKMDQLLLEKKRD 888
Cdd:PRK03918   232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELRE 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  889 VETLQQTIEEKDQQVTEisfsmteKMVQLNEEKfslgVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSP 968
Cdd:PRK03918   312 IEKRLSRLEEEINGIEE-------RIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKR 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  969 AGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKdESKKEIPLSETERGEVEEDKENKEYse 1048
Cdd:PRK03918   381 LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK-KAKGKCPVCGRELTEEHRKELLEEY-- 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1049 kcvTSKCQEIEIYLKqTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQ--TLQDKTNQIDL--LQAEISENQAIIQK 1124
Cdd:PRK03918   458 ---TAELKRIEKELK-EIEEKERKLRKELRELEKVLKKESELIKLKELAEQlkELEEKLKKYNLeeLEKKAEEYEKLKEK 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 1125 LITSntdasDGDSVALVKETvvisppctgssehwkpeleEKILALEKEKEQLQKKLQEALTSRKAILKKAQEK----ERH 1200
Cdd:PRK03918   534 LIKL-----KGEIKSLKKEL-------------------EKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEE 589

                          410
                   ....*....|....
gi 1034632653 1201 LREELKQQKDDYNR 1214
Cdd:PRK03918   590 LEERLKELEPFYNE 603
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2471-2757 8.73e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 8.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2471 NDRDRIVGDY-------QQLEErhlsiileKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdAELIQYREDLNQV 2543
Cdd:COG4913    593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2544 itikDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2621
Cdd:COG4913    664 ----ASAEREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653 2622 QEEGTLGLyHAQLkvkeeEVHRLSALFSSSQKRIAE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2700
Cdd:COG4913    740 EDLARLEL-RALL-----EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034632653 2701 AEERVAELAR----DLVEMEQKLLMVTKENkgltaQIQSFGRSMSSLQNSRDHANEELDEL 2757
Cdd:COG4913    814 LPEYLALLDRleedGLPEYEERFKELLNEN-----SIEFVADLLSKLRRAIREIKERIDPL 869
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
811-1001 9.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  811 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN--KESEVLEGAERVRHISSKVEELSQALSQKELEITKmdqlLLEKKRD 888
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  889 VETLQQTIEEKDQQVTEisfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEE-DNEVSSGLKQNYDEMS 967
Cdd:COG4913    687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERF 755

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034632653  968 PAGQISK--EELQHEFDLLKKENEQRKRKLQAALIN 1001
Cdd:COG4913    756 AAALGDAveRELRENLEERIDALRARLNRAEEELER 791
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 243-353 9.96e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.86  E-value: 9.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034632653  243 QADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR-NTVETEREeskill 321
Cdd:PRK11448   140 PENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQeKAAETSQE------ 213

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1034632653  322 EKMEL-EVAERKLSFHNLQEEMHHLL--EQFEQAG 353
Cdd:PRK11448   214 RKQKRkEITDQAAKRLELSEEETRILidQQLRKAG 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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