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Conserved domains on  [gi|1034580524|ref|XP_016875106|]
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heme transporter HRG1 isoform X3 [Homo sapiens]

Protein Classification

HRG domain-containing protein( domain architecture ID 11246531)

HRG domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HRG pfam16954
Haem-transporter, endosomal/lysosomal, haem-responsive gene; HRG1 is a family of conserved, ...
 72-122 4.73e-13

Haem-transporter, endosomal/lysosomal, haem-responsive gene; HRG1 is a family of conserved, membrane-bound permeases that reside in distinct intracellular compartments and bind and transport haem in metazoa. These proteins carry four transmembrane domains, 4xTMs, modelled here in two pairs, the two N-terminal and the two more C-terminal.


:

Pssm-ID: 465321  Cd Length: 51  Bit Score: 59.66  E-value: 4.73e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1034580524  72 RGFFFVGVLFSAVSIAAFCTFLVLAITRHQSLTDPTSYYLSSVWSFISFKW 122
Cdd:pfam16954   1 RFRIAYGIFGSLLGLSAFLVWLVLAIYRKQGLTDPRSLYLSAVWSLMTLKW 51
 
Name Accession Description Interval E-value
HRG pfam16954
Haem-transporter, endosomal/lysosomal, haem-responsive gene; HRG1 is a family of conserved, ...
 72-122 4.73e-13

Haem-transporter, endosomal/lysosomal, haem-responsive gene; HRG1 is a family of conserved, membrane-bound permeases that reside in distinct intracellular compartments and bind and transport haem in metazoa. These proteins carry four transmembrane domains, 4xTMs, modelled here in two pairs, the two N-terminal and the two more C-terminal.


Pssm-ID: 465321  Cd Length: 51  Bit Score: 59.66  E-value: 4.73e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1034580524  72 RGFFFVGVLFSAVSIAAFCTFLVLAITRHQSLTDPTSYYLSSVWSFISFKW 122
Cdd:pfam16954   1 RFRIAYGIFGSLLGLSAFLVWLVLAIYRKQGLTDPRSLYLSAVWSLMTLKW 51
 
Name Accession Description Interval E-value
HRG pfam16954
Haem-transporter, endosomal/lysosomal, haem-responsive gene; HRG1 is a family of conserved, ...
 72-122 4.73e-13

Haem-transporter, endosomal/lysosomal, haem-responsive gene; HRG1 is a family of conserved, membrane-bound permeases that reside in distinct intracellular compartments and bind and transport haem in metazoa. These proteins carry four transmembrane domains, 4xTMs, modelled here in two pairs, the two N-terminal and the two more C-terminal.


Pssm-ID: 465321  Cd Length: 51  Bit Score: 59.66  E-value: 4.73e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1034580524  72 RGFFFVGVLFSAVSIAAFCTFLVLAITRHQSLTDPTSYYLSSVWSFISFKW 122
Cdd:pfam16954   1 RFRIAYGIFGSLLGLSAFLVWLVLAIYRKQGLTDPRSLYLSAVWSLMTLKW 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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