NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1034595921|ref|XP_016879140|]
View 

Golgi apparatus membrane protein TVP23 homolog A isoform X2 [Homo sapiens]

Protein Classification

DUF846 domain-containing protein( domain architecture ID 10530749)

DUF846 domain-containing protein similar to Saccharomyces cerevisiae Golgi apparatus membrane protein TVP23 that is involved in vesicular trafficking

Gene Ontology:  GO:0016020|GO:0016192|GO:0009306

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF846 pfam05832
Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown ...
 1-107 1.58e-44

Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown function from a variety of eukaryotic organizms.


:

Pssm-ID: 461754  Cd Length: 139  Bit Score: 142.71  E-value: 1.58e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034595921   1 MVLLLLSLDFWSVKNVTGRLLVGLRWWNQIDEDGKSHWIFEARkvsPNSIAATEAEARIFWLGLIICPMIWIVFFFSTLF 80
Cdd:pfam05832  36 IVILLLALDFWTVKNITGRLLVGLRWWNEVDEDGESTWVFESR---DPKRPVNAIDSKLFWLSLYVTPLIWILLLIVAII 112

                          90       100
                  ....*....|....*....|....*..
gi 1034595921  81 SLKLKWLALVVAGISLQAANLYGYILC 107
Cdd:pfam05832 113 SLKFFWLLLVIIALVLNGTNLYGFYKC 139
 
Name Accession Description Interval E-value
DUF846 pfam05832
Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown ...
 1-107 1.58e-44

Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown function from a variety of eukaryotic organizms.


Pssm-ID: 461754  Cd Length: 139  Bit Score: 142.71  E-value: 1.58e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034595921   1 MVLLLLSLDFWSVKNVTGRLLVGLRWWNQIDEDGKSHWIFEARkvsPNSIAATEAEARIFWLGLIICPMIWIVFFFSTLF 80
Cdd:pfam05832  36 IVILLLALDFWTVKNITGRLLVGLRWWNEVDEDGESTWVFESR---DPKRPVNAIDSKLFWLSLYVTPLIWILLLIVAII 112

                          90       100
                  ....*....|....*....|....*..
gi 1034595921  81 SLKLKWLALVVAGISLQAANLYGYILC 107
Cdd:pfam05832 113 SLKFFWLLLVIIALVLNGTNLYGFYKC 139
 
Name Accession Description Interval E-value
DUF846 pfam05832
Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown ...
 1-107 1.58e-44

Eukaryotic protein of unknown function (DUF846); This family consists of several of unknown function from a variety of eukaryotic organizms.


Pssm-ID: 461754  Cd Length: 139  Bit Score: 142.71  E-value: 1.58e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034595921   1 MVLLLLSLDFWSVKNVTGRLLVGLRWWNQIDEDGKSHWIFEARkvsPNSIAATEAEARIFWLGLIICPMIWIVFFFSTLF 80
Cdd:pfam05832  36 IVILLLALDFWTVKNITGRLLVGLRWWNEVDEDGESTWVFESR---DPKRPVNAIDSKLFWLSLYVTPLIWILLLIVAII 112

                          90       100
                  ....*....|....*....|....*..
gi 1034595921  81 SLKLKWLALVVAGISLQAANLYGYILC 107
Cdd:pfam05832 113 SLKFFWLLLVIIALVLNGTNLYGFYKC 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH