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Conserved domains on  [gi|1034675746|ref|XP_016885479|]
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armadillo repeat-containing X-linked protein 2 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


:

Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034675746 543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 super family cl35530
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07003:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003  379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003  520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593

                  ..
gi 1034675746 278 VP 279
Cdd:PRK07003  594 VQ 595
 
Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034675746 543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003  379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003  520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593

                  ..
gi 1034675746 278 VP 279
Cdd:PRK07003  594 VQ 595
VATPase_H cd00256
VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the ...
388-455 1.68e-03

VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The topology is that of a superhelical spiral, in part the geometry is similar to superhelices composed of armadillo repeat motifs, as found in importins for example.


Pssm-ID: 238159 [Multi-domain]  Cd Length: 429  Bit Score: 41.23  E-value: 1.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034675746 388 LRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
Cdd:cd00256   355 LKILIHLLETSVDPIILAVACHDIGEYVRhYPRGKDVVEQLGGKQRVMRLLNHEDPNVRYEALLAVQKL 423
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
420-456 2.33e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.87  E-value: 2.33e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1034675746  420 NQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLS 456
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
KLF9_13_N-like cd21975
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ...
164-290 8.54e-03

Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.


Pssm-ID: 409240 [Multi-domain]  Cd Length: 163  Bit Score: 37.36  E-value: 8.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 164 AEAPREAETSRAAVPPG----TVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESP 239
Cdd:cd21975    31 AAGLDVRATREVAKGPGppgpAWKPDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESGDADMGSDSDVAPASGAAA 110
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1034675746 240 GTSgsprtavvPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:cd21975   111 STS--------PESSSDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRR 153
 
Name Accession Description Interval E-value
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
383-601 6.58e-116

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 344.78  E-value: 6.58e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 383 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQ 462
Cdd:pfam04826   1 LEPQELDKLLALLKSSEDPFIHEIALITLGNSAAYPFNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVENQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 463 GRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDML 542
Cdd:pfam04826  81 KKIKVYVNQVCKDIVSSPLNSEVQLAGLKLLTNLSVTNDYHHLVVSYIRDFFSLLSQGNEKTKFQVLKVLLNLSENPAMT 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034675746 543 KKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAE--VFNYREFNKGSLFYLCT 601
Cdd:pfam04826 161 RELLSAQVPSSLLSLFNSKEAKENLLRALTIFENINFHLKKEakLFVKEHFTKGSLFSIFR 221
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
39-279 2.00e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 57.55  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  39 AKPKNRAVAGTGARARAGLRAGftidlgsgfspPTPVRAEAEDRAQDEASAldtVGAEAVAPAASSAEAQSGAgsqaqEA 118
Cdd:PRK07003  379 AVPAPGARAAAAVGASAVPAVT-----------AVTGAAGAALAPKAAAAA---AATRAEAPPAAPAPPATAD-----RG 439
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 119 DGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPR-EAETSRAAVPPGTVVPTEAAAPTEVTEGP 197
Cdd:PRK07003  440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfEPAPRAAAPSAATPAAVPDARAPAAASRE 519
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 198 GVAAPTKVAeAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRtavvpGTSAAKKATPGAHTGAIPKATSATGA 277
Cdd:PRK07003  520 DAPAAAAPP-APEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDR-----GARAAAAAKPAAAPAAAPKPAAPRVA 593

                  ..
gi 1034675746 278 VP 279
Cdd:PRK07003  594 VQ 595
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
49-280 9.31e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 55.24  E-value: 9.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  49 TGARARAGLR----AGFTIDL---------------GSGFSPPTPVRA--EAEDRAQDEASALDTVGAEAVAPAASSAEA 107
Cdd:PRK07003  332 TVGRGELGLApdeyAGFTMTLlrmlafepavtgggaPGGGVPARVAGAvpAPGARAAAAVGASAVPAVTAVTGAAGAALA 411
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 108 QSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEA 187
Cdd:PRK07003  412 PKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFE 491
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 188 AAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATP--GAHT 265
Cdd:PRK07003  492 PAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSdrGARA 571
                         250
                  ....*....|....*
gi 1034675746 266 GAIPKATSATGAVPK 280
Cdd:PRK07003  572 AAAAKPAAAPAAAPK 586
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
59-272 2.44e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 53.73  E-value: 2.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  59 AGFTIDL-----------GSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKA 127
Cdd:PRK12323  351 AGFTMTLlrmlafrpgqsGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAP 430
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 128 ESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEV---TEGPG-VAAPT 203
Cdd:PRK12323  431 EALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPppwEELPPeFASPA 510
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034675746 204 KVAEAPGVAsPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKAT 272
Cdd:PRK12323  511 PAQPDAAPA-GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFD 578
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
97-282 3.15e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 53.70  E-value: 3.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  97 AVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPG-VTEALGAAEAPAMAGAPKVAEAPREA----- 170
Cdd:PRK07003  357 AFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGaAGAALAPKAAAAAAATRAEAPPAAPAppata 436
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 171 -ETSRAAVPPGTVvPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAV 249
Cdd:PRK07003  437 dRGDDAADGDAPV-PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAA 515
                         170       180       190
                  ....*....|....*....|....*....|...
gi 1034675746 250 VPGTSAAKKATPGAHTGAIPKATSATGAVPKGG 282
Cdd:PRK07003  516 ASREDAPAAAAPPAPEARPPTPAAAAPAARAGG 548
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
35-271 1.69e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 51.14  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  35 KKRMAKPKNRAVAGTGARARAGLRAGFT--IDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAvAPAASSAEAQSGAG 112
Cdd:PRK07764  558 ARRFASPGNAEVLVTALAEELGGDWQVEavVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPA-APAAPAPAGAAAAP 636
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 113 SQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagapkvAEAPREAETSRAAVPPGTVVPTEAAAPTE 192
Cdd:PRK07764  637 AEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAK---------------AGGAAPAAPPPAPAPAAPAAPAGAAPAQP 701
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034675746 193 VTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKA 271
Cdd:PRK07764  702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
PHA03247 PHA03247
large tegument protein UL36; Provisional
71-281 1.40e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 1.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQ------EADGAGVGPKAESVVGAAMASAIAPPPG 144
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSArprapvDDRGDPRGPAPPSPLPPDTHAPDPPPPS 2630
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  145 VTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGpgvaaPTKVAEAPGVASPTEAAEAPvpa 224
Cdd:PHA03247  2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQR-----PRRRAARPTVGSLTSLADPP--- 2702
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034675746  225 tptgaaAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKG 281
Cdd:PHA03247  2703 ------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG 2753
PHA03247 PHA03247
large tegument protein UL36; Provisional
11-280 1.94e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746   11 AAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPKNRAVA-GTGARARAGLR------AGFTIDLGSGFSPPTPVRAEAEDRA 83
Cdd:PHA03247  2633 PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRlGRAAQASSPPQrprrraARPTVGSLTSLADPPPPPPTPEPAP 2712
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746   84 QDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKV 163
Cdd:PHA03247  2713 HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA------------GPP 2780
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  164 AEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPvpatptgaaaPTGAAESPGTSG 243
Cdd:PHA03247  2781 RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTA----------PPPPPGPPPPSL 2850
                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1034675746  244 SPRTAVVPGTSAAKKATPGAhtgaiPKATSATGAVPK 280
Cdd:PHA03247  2851 PLGGSVAPGGDVRRRPPSRS-----PAAKPAAPARPP 2882
PHA03247 PHA03247
large tegument protein UL36; Provisional
71-282 3.11e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 3.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVG-----PKAESVVGAAMASAIAPPPGV 145
Cdd:PHA03247  2627 PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrprrRAARPTVGSLTSLADPPPPPP 2706
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  146 TEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEV--------TEGPG--------VAAPTKVAEAP 209
Cdd:PHA03247  2707 TPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGParparpptTAGPPapappaapAAGPPRRLTRP 2786
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034675746  210 GVASPTEAAEA-PVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKGG 282
Cdd:PHA03247  2787 AVASLSESRESlPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG 2860
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
83-223 1.04e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 45.48  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  83 AQDEASALDTV-----------GAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVtealga 151
Cdd:PRK14951  347 APDEYAALTMVllrllafkpaaAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAA------ 420
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 152 aeapamagapkVAEAPREAETSRAAVPPGTVVPTEAA---APTEVTEGPGVAAPTKVAEAPGVASPTEA-----AEAPVP 223
Cdd:PRK14951  421 -----------APPAPVAAPAAAAPAAAPAAAPAAVAlapAPPAQAAPETVAIPVRVAPEPAVASAAPApaaapAAARLT 489
rne PRK10811
ribonuclease E; Reviewed
72-247 2.14e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 44.65  E-value: 2.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746   72 PTPVRAEAEDRAQDEASALDTVGAEAVAPAA-----SSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPpgVT 146
Cdd:PRK10811   848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAvepvvSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAP--VT 925
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  147 EALGAAEApamagapkvAEAPREAETSRAAVPPGTVVP-TEAAAPTEVTEGPGVAAPTKVAEAPGVA---SPTEAAEAPV 222
Cdd:PRK10811   926 EQPQVITE---------SDVAVAQEVAEHAEPVVEPQDeTADIEEAAETAEVVVAEPEVVAQPAAPVvaeVAAEVETVTA 996
                          170       180
                   ....*....|....*....|....*
gi 1034675746  223 PATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK10811   997 VEPEVAPAQVPEATVEHNHATAPMT 1021
rne PRK10811
ribonuclease E; Reviewed
71-221 2.35e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 44.26  E-value: 2.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746   71 PPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPppgVTEAlg 150
Cdd:PRK10811   878 AVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEP---VVEP-- 952
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034675746  151 aaeapamagAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPgVAAPTKVAEAPGVASPTEA------AEAP 221
Cdd:PRK10811   953 ---------QDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAE-VETVTAVEPEVAPAQVPEAtvehnhATAP 1019
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
134-284 2.70e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.79  E-value: 2.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 134 AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAET--SRAAVPPGTVvpteAAAPTEVTEGPG--VAAPTKVAEAP 209
Cdd:PTZ00436  203 AAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAapAKAAAAPAKA----AAPPAKAAAPPAkaAAPPAKAAAPP 278
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034675746 210 GVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSA---AKKATPGAHTGAIPKATSATGAVPKGGGK 284
Cdd:PTZ00436  279 AKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAappAKAATPPAKAAAPPAKAAAAPVGKKAGGK 356
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
94-290 2.96e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.10  E-value: 2.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  94 GAEAVAPAASSAEAQSGAGSQAQEAdgAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETS 173
Cdd:PRK12323  370 GGAGPATAAAAPVAQPAPAAAAPAA--AAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 174 R--AAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVAS------PTEAAEAPVPATPTGAAAPTGAAESPGTSGSP 245
Cdd:PRK12323  448 PapAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPapadddPPPWEELPPEFASPAPAQPDAAPAGWVAESIP 527
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1034675746 246 RTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:PRK12323  528 DPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
41-279 3.59e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 3.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  41 PKNRAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADG 120
Cdd:PRK07764  435 PAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRE 514
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 121 ------AGVG-------------PKAESVVG---------AAMASAIAPPPG---VTEALGAAEAPAMAGAPKVAEAPRE 169
Cdd:PRK07764  515 rwpeilAAVPkrsrktwaillpeATVLGVRGdtlvlgfstGGLARRFASPGNaevLVTALAEELGGDWQVEAVVGPAPGA 594
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 170 AETSRAAVPPGTVVPTEAAAPTEVT--EGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK07764  595 AGGEGPPAPASSGPPEEAARPAAPAapAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAG 674
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1034675746 248 AVVPgTSAAKKATPGAHTGAIPKATSATGAVP 279
Cdd:PRK07764  675 GAAP-AAPPPAPAPAAPAAPAGAAPAQPAPAP 705
PHA03247 PHA03247
large tegument protein UL36; Provisional
71-280 3.91e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 3.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746   71 PPTPVRAEAEDRAQDEASALDTV----GAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAiAPPPGVT 146
Cdd:PHA03247  2702 PPPPPTPEPAPHALVSATPLPPGpaaaRQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA-APAAGPP 2780
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  147 EALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEA--------- 217
Cdd:PHA03247  2781 RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlggsvapgg 2860
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  218 -------AEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPK 280
Cdd:PHA03247  2861 dvrrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ 2930
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
9-243 5.65e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 5.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746   9 CVAAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPkNRAVAGTGARARAGLRAGftiDLGSGFSPPTPVRAEAEDRAQDEAS 88
Cdd:PRK07764  586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAP-AAPAAPAAPAPAGAAAAP---AEASAAPAPGVAAPEHHPKHVAVPD 661
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  89 ALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAEsvvgAAMASAIAPPPGVTEALGAAEAPAmagapkvAEAPR 168
Cdd:PRK07764  662 ASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQP----APAPAATPPAGQADDPAAQPPQAA-------QGASA 730
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034675746 169 EAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSG 243
Cdd:PRK07764  731 PSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVA 805
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
51-222 9.03e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 9.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  51 ARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQE-ADGAGVGPKAES 129
Cdd:PRK12323  405 APAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPvAAAAAAAPARAA 484
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 130 VVGAAMASAIAPPPgvTEALGAAEAPAMAGAPKVAEAPREAETS--------RAAVPPGTVVPTEAAAPTEVTEGPGVAA 201
Cdd:PRK12323  485 PAAAPAPADDDPPP--WEELPPEFASPAPAQPDAAPAGWVAESIpdpatadpDDAFETLAPAPAAAPAPRAAAATEPVVA 562
                         170       180
                  ....*....|....*....|.
gi 1034675746 202 PTKVAEAPGVASPTEAAEAPV 222
Cdd:PRK12323  563 PRPPRASASGLPDMFDGDWPA 583
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
44-242 1.04e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  44 RAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRA---EAEDRAQDEASALDTVGAEAVAPA-ASSAEAQSGAGSQAQEAD 119
Cdd:PRK12323  376 TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAApaaAAAARAVAAAPARRSPAPEALAAArQASARGPGGAPAPAPAPA 455
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 120 GAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAetsrAAVPPGTVVPTEAAAPTEVTEGPGV 199
Cdd:PRK12323  456 AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEF----ASPAPAQPDAAPAGWVAESIPDPAT 531
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1034675746 200 AAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTS 242
Cdd:PRK12323  532 ADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLP 574
VATPase_H cd00256
VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the ...
388-455 1.68e-03

VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The topology is that of a superhelical spiral, in part the geometry is similar to superhelices composed of armadillo repeat motifs, as found in importins for example.


Pssm-ID: 238159 [Multi-domain]  Cd Length: 429  Bit Score: 41.23  E-value: 1.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034675746 388 LRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
Cdd:cd00256   355 LKILIHLLETSVDPIILAVACHDIGEYVRhYPRGKDVVEQLGGKQRVMRLLNHEDPNVRYEALLAVQKL 423
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
76-221 1.68e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.09  E-value: 1.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  76 RAEAEDRAQDEASALDTVGAEAVAPAAS-SAEAQSGAGSQAQEADGAGVGPKAESV-VGAAMASAIAPPPGVTEALGAAE 153
Cdd:PTZ00436  187 RARREDAAAAAAAKQKAAAKKAAAPSGKkSAKAAAPAKAAAAPAKAAAPPAKAAAApAKAAAAPAKAAAPPAKAAAPPAK 266
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034675746 154 APAMAGAPKVAEAPREAETSRAAVPPGTVvpteAAAPTEVTEGPG--VAAPTKVAEAPG--VASPTEAAEAP 221
Cdd:PTZ00436  267 AAAPPAKAAAPPAKAAAPPAKAAAPPAKA----AAAPAKAAAAPAkaAAAPAKAAAPPAkaAAPPAKAATPP 334
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
93-221 2.20e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  93 VGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPgvtealgaaeapaMAGAPKVAEAPREAET 172
Cdd:PRK07764  386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPA-------------PAPAPPSPAGNAPAGG 452
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1034675746 173 SRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAP 221
Cdd:PRK07764  453 APSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPA 501
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
420-456 2.33e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.87  E-value: 2.33e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1034675746  420 NQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLS 456
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
rne PRK10811
ribonuclease E; Reviewed
100-279 2.60e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.18  E-value: 2.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  100 PAASSAEAQSGAGSQAQEADGAgvgPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKVAEAP--REAETSRAAV 177
Cdd:PRK10811   846 PVVRPQDVQVEEQREAEEVQVQ---PVVAEVPVAAAVEPVVSAPVVEAV------------AEVVEEPvvVAEPQPEEVV 910
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  178 PPGTVVPTEAAAPteVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAK 257
Cdd:PRK10811   911 VVETTHPEVIAAP--VTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVA 988
                          170       180
                   ....*....|....*....|..
gi 1034675746  258 KATPGAHTGAIPKATSATGAVP 279
Cdd:PRK10811   989 AEVETVTAVEPEVAPAQVPEAT 1010
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
47-220 3.14e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 40.35  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  47 AGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRA--------QDEASALDTvGAEAVAPAASSAEAQSGAGSQAQEA 118
Cdd:PRK13108  275 APKGREAPGALRGSEYVVDEALEREPAELAAAAVASAasavgpvgPGEPNQPDD-VAEAVKAEVAEVTDEVAAESVVQVA 353
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 119 DGagVGPKAESVVGAAMASAIAPPPGVTEAlgaaeapamagaPKVAEAPREAETSRAAvppgtvvPTEAAA-PTEVTEGP 197
Cdd:PRK13108  354 DR--DGESTPAVEETSEADIEREQPGDLAG------------QAPAAHQVDAEAASAA-------PEEPAAlASEAHDET 412
                         170       180
                  ....*....|....*....|...
gi 1034675746 198 GVAAPTKVAEAPGVASPTEAAEA 220
Cdd:PRK13108  413 EPEVPEKAAPIPDPAKPDELAVA 435
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
136-262 3.18e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 136 ASAIAPPPGVTEALGAAEAPAmagAPKVAEAPREAETSRAAVPPGTVVPTeAAAPTEVTEGPGVAAPTKVAEAPGVASPT 215
Cdd:PRK14951  368 AAAEAAAPAEKKTPARPEAAA---PAAAPVAQAAAAPAPAAAPAAAASAP-AAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1034675746 216 EAAEAPVPATPTGA-AAPTGAAESPGTSGSPRTAVVPGTSAAKKATPG 262
Cdd:PRK14951  444 AVALAPAPPAQAAPeTVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
168-279 3.18e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 168 REAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRT 247
Cdd:PRK07764  383 RRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAP 462
                          90       100       110
                  ....*....|....*....|....*....|..
gi 1034675746 248 AVVPGTSAAKKATPGAHTGAIPKATSATGAVP 279
Cdd:PRK07764  463 SAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAP 494
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
40-189 5.51e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.70  E-value: 5.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  40 KPKNRAVAGTGARARAGLRAgftidlgsgfSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAeAQSGAGSQAQEAD 119
Cdd:PRK14951  365 KPAAAAEAAAPAEKKTPARP----------EAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAA-APPAPVAAPAAAA 433
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034675746 120 GAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTV----VPTEAAA 189
Cdd:PRK14951  434 PAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVwhatVQQLAAA 507
PRK12727 PRK12727
flagellar biosynthesis protein FlhF;
71-224 7.01e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 237182 [Multi-domain]  Cd Length: 559  Bit Score: 39.59  E-value: 7.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  71 PPTPVRAEAEDRAQDEASALDTVgaeavapaASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASA----IAPPPGVT 146
Cdd:PRK12727   79 PAAPVHAPLKLSANANMSQRQRV--------ASAAEDMIAAMALRQPVSVPRQAPAAAPVRAASIPSPaaqaLAHAAAVR 150
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034675746 147 EALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTeAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPA 224
Cdd:PRK12727  151 TAPRQEHALSAVPEQLFADFLTTAPVPRAPVQAPVVAAP-APVPAIAAALAAHAAYAQDDDEQLDDDGFDLDDALPQI 227
KLF9_13_N-like cd21975
Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like ...
164-290 8.54e-03

Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins, called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. KLF9, KLF10, KLF11, KLF13, KLF14, and KLF16 share a conserved alpha-helical motif AA/VXXL that mediates their binding to Sin3A and their activities as transcriptional repressors. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the related N-terminal domains of KLF9, KLF13, KLF14, KLF16, and similar proteins.


Pssm-ID: 409240 [Multi-domain]  Cd Length: 163  Bit Score: 37.36  E-value: 8.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 164 AEAPREAETSRAAVPPG----TVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESP 239
Cdd:cd21975    31 AAGLDVRATREVAKGPGppgpAWKPDGADSPGLVTAAPHLLAANVLAPLRGPSVEGSSLESGDADMGSDSDVAPASGAAA 110
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1034675746 240 GTSgsprtavvPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSR 290
Cdd:cd21975   111 STS--------PESSSDAASSPSPLSLLHPGEAGLEPERPRPRVRRGVRRR 153
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
70-214 9.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.06  E-value: 9.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  70 SPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASS----AEAQSGAGSQAQEADGAGVGPKAESVvGAAMASAIAPPPGV 145
Cdd:PRK07003  483 DAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASredaPAAAAPPAPEARPPTPAAAAPAARAG-GAAAALDVLRNAGM 561
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034675746 146 TeaLGAAEAPAMAGAPKVAEAPREAETSrAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASP 214
Cdd:PRK07003  562 R--VSSDRGARAAAAAKPAAAPAAAPKP-AAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPP 627
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
82-263 9.66e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 38.81  E-value: 9.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746  82 RAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPkAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAP 161
Cdd:PRK13108  277 KGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGP-GEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADR 355
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675746 162 KVAEAPREAETSRAAVppgtvvptEAAAPTEvTEGPGVAAPtKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGT 241
Cdd:PRK13108  356 DGESTPAVEETSEADI--------EREQPGD-LAGQAPAAH-QVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPD 425
                         170       180
                  ....*....|....*....|..
gi 1034675746 242 SGSPRTAVVPGTSAAKKATPGA 263
Cdd:PRK13108  426 PAKPDELAVAGPGDDPAEPDGI 447
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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