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Conserved domains on  [gi|1039749675|ref|XP_017172275|]
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tetratricopeptide repeat protein 23-like isoform X1 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-427 9.65e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 9.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 131 AQALANLAYGYLTlRGLPAQAKKHAEKARNtlltwkrnttSDKDKKEILETLVRLYYTLGvawllqnhgkqayiHLQKAE 210
Cdd:COG2956    42 VEAHLALGNLYRR-RGEYDRAIRIHQKLLE----------RDPDRAEALLELAQDYLKAG--------------LLDRAE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 211 RNMKELKELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvildkgHNTSELISLYEEIAQIEQLRKNH 290
Cdd:COG2956    97 ELLEKLLELDPDDA--------EALRLLAEIYEQEGDWEKAIEVLERLL--------KLGPENAHAYCELAELYLEQGDY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 291 KQAIQYLQQAYsicvssfsEVSPQTAEASALLAKAYAMSGasEYRDAVEIyfirsistYQTLGSEDYETLTAIEDFCTWL 370
Cdd:COG2956   161 DEAIEALEKAL--------KLDPDCARALLLLAELYLEQG--DYEEAIAA--------LERALEQDPDYLPALPRLAELY 222

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039749675 371 IENGEKQEAYRLLKSTLNSGNFgdcgkkvAETFYNMGSICFAKGELGEAIELLSKCL 427
Cdd:COG2956   223 EKLGDPEEALELLRKALELDPS-------DDLLLALADLLERKEGLEAALALLERQL 272
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-427 9.65e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 9.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 131 AQALANLAYGYLTlRGLPAQAKKHAEKARNtlltwkrnttSDKDKKEILETLVRLYYTLGvawllqnhgkqayiHLQKAE 210
Cdd:COG2956    42 VEAHLALGNLYRR-RGEYDRAIRIHQKLLE----------RDPDRAEALLELAQDYLKAG--------------LLDRAE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 211 RNMKELKELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvildkgHNTSELISLYEEIAQIEQLRKNH 290
Cdd:COG2956    97 ELLEKLLELDPDDA--------EALRLLAEIYEQEGDWEKAIEVLERLL--------KLGPENAHAYCELAELYLEQGDY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 291 KQAIQYLQQAYsicvssfsEVSPQTAEASALLAKAYAMSGasEYRDAVEIyfirsistYQTLGSEDYETLTAIEDFCTWL 370
Cdd:COG2956   161 DEAIEALEKAL--------KLDPDCARALLLLAELYLEQG--DYEEAIAA--------LERALEQDPDYLPALPRLAELY 222

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039749675 371 IENGEKQEAYRLLKSTLNSGNFgdcgkkvAETFYNMGSICFAKGELGEAIELLSKCL 427
Cdd:COG2956   223 EKLGDPEEALELLRKALELDPS-------DDLLLALADLLERKEGLEAALALLERQL 272
TPR_12 pfam13424
Tetratricopeptide repeat;
272-341 6.66e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.92  E-value: 6.66e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 272 ELISLYEEIAQIEQLRKNHKQAIQYLQQAYSICVSSFSEVSPQTAEASALLAKAYAMSGasEYRDAVEIY 341
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELG--RYEEALELL 68
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 256-341 8.64e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 41.72  E-value: 8.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 256 EKAIcDVI-----LDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSicvssfseVSPQTAEASALLAKAYAMSG 330
Cdd:PRK11788  158 QKAI-DVAerlekLGGDSLRVEIAHFYCELAQQALARGDLDAARALLKKALA--------ADPQCVRASILLGDLALAQG 228

                          90
                  ....*....|.
gi 1039749675 331 asEYRDAVEIY 341
Cdd:PRK11788  229 --DYAAAIEAL 237
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-427 9.65e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 9.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 131 AQALANLAYGYLTlRGLPAQAKKHAEKARNtlltwkrnttSDKDKKEILETLVRLYYTLGvawllqnhgkqayiHLQKAE 210
Cdd:COG2956    42 VEAHLALGNLYRR-RGEYDRAIRIHQKLLE----------RDPDRAEALLELAQDYLKAG--------------LLDRAE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 211 RNMKELKELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvildkgHNTSELISLYEEIAQIEQLRKNH 290
Cdd:COG2956    97 ELLEKLLELDPDDA--------EALRLLAEIYEQEGDWEKAIEVLERLL--------KLGPENAHAYCELAELYLEQGDY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 291 KQAIQYLQQAYsicvssfsEVSPQTAEASALLAKAYAMSGasEYRDAVEIyfirsistYQTLGSEDYETLTAIEDFCTWL 370
Cdd:COG2956   161 DEAIEALEKAL--------KLDPDCARALLLLAELYLEQG--DYEEAIAA--------LERALEQDPDYLPALPRLAELY 222

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039749675 371 IENGEKQEAYRLLKSTLNSGNFgdcgkkvAETFYNMGSICFAKGELGEAIELLSKCL 427
Cdd:COG2956   223 EKLGDPEEALELLRKALELDPS-------DDLLLALADLLERKEGLEAALALLERQL 272
TPR_12 pfam13424
Tetratricopeptide repeat;
272-341 6.66e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.92  E-value: 6.66e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 272 ELISLYEEIAQIEQLRKNHKQAIQYLQQAYSICVSSFSEVSPQTAEASALLAKAYAMSGasEYRDAVEIY 341
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELG--RYEEALELL 68
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 186-427 1.59e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.65  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 186 YYTLGVAWLLQNHGKQAYIHLQKAErnmkelkELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvild 265
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEAL-------ELDPETV--------EAHLALGNLYRRRGEYDRAIRIHQKLL------ 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 266 kgHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAysicvssfSEVSPQTAEASALLAKAYAMSGasEYRDAVEIYfiRS 345
Cdd:COG2956    70 --ERDPDRAEALLELAQDYLKAGLLDRAEELLEKL--------LELDPDDAEALRLLAEIYEQEG--DWEKAIEVL--ER 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 346 ISTYQTLGSEDYETLTAIedfctwLIENGEKQEAYRLLKSTLNSgnfgdcGKKVAETFYNMGSICFAKGELGEAIELLSK 425
Cdd:COG2956   136 LLKLGPENAHAYCELAEL------YLEQGDYDEAIEALEKALKL------DPDCARALLLLAELYLEQGDYEEAIAALER 203


                  ..
gi 1039749675 426 CL 427
Cdd:COG2956   204 AL 205
COG3899 COG3899
Predicted ATPase [General function prediction only];
264-429 6.85e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 45.62  E-value: 6.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675  264 LDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSICvssfSEVSPQTAEASALLAKAYAMSGASEYRDAVEIY-F 342
Cdd:COG3899    695 LNRAGERDRAARLLLRAARRALARGAYAEALRYLERALELL----PPDPEEEYRLALLLELAEALYLAGRFEEAEALLeR 770

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675  343 IRSISTYQTLGSEDYETLTAIEDFCTWL--IENGEKQEAYRLLKSTLNSGNFGDCGKKVAETFYNMGSICFAKGELGEAI 420
Cdd:COG3899    771 ALAARALAALAALRHGNPPASARAYANLglLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREAL 850


                   ....*....
gi 1039749675  421 ELLSKCLMI 429
Cdd:COG3899    851 ELLREALEA 859
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
131-341 2.04e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.07  E-value: 2.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 131 AQALANLAYGYLTLrGLPAQAKKHAEKARntlltwkrnttsdkdkkEILETLVRLYYTLGVAWLLQNHGKQAYIHLQKA- 209
Cdd:COG0457     8 AEAYNNLGLAYRRL-GRYEEAIEDYEKAL-----------------ELDPDDAEALYNLGLAYLRLGRYEEALADYEQAl 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 210 ERNMKELKELNNgnicgiqvsekdltiaLGRASLAMHRMNLALAYFEKAIcdvILDkghntSELISLYEEIAQIEQLRKN 289
Cdd:COG0457    70 ELDPDDAEALNN----------------LGLALQALGRYEEALEDYDKAL---ELD-----PDDAEALYNLGLALLELGR 125

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1039749675 290 HKQAIQYLQQAYSIcvssfsevSPQTAEASALLAKAYAMSGasEYRDAVEIY 341
Cdd:COG0457   126 YDEAIEAYERALEL--------DPDDADALYNLGIALEKLG--RYEEALELL 167
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 238-341 2.77e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.76  E-value: 2.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 238 LGRASLAMHRMNLALAYFEKAICdviLDKGHntselISLYEEIAQIEQLRKNHKQAIQYLQQAYSIcvssfsevSPQTAE 317
Cdd:COG4235    23 LGRAYLRLGRYDEALAAYEKALR---LDPDN-----ADALLDLAEALLAAGDTEEAEELLERALAL--------DPDNPE 86

                          90       100
                  ....*....|....*....|....
gi 1039749675 318 ASALLAKAYAMSGasEYRDAVEIY 341
Cdd:COG4235    87 ALYLLGLAAFQQG--DYAEAIAAW 108
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 238-425 5.42e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 5.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 238 LGRASLAMHRMNLALAY-----FEKAIcDVILDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYsicvssfsEVS 312
Cdd:COG2956     2 LLPVAAALGWYFKGLNYllngqPDKAI-DLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLL--------ERD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 313 PQTAEASALLAKAYAMSGasEYRDAVEIyfirsistYQTLGSEDYETLTAIEDFCTWLIENGEKQEAYRLLKSTLNSgnf 392
Cdd:COG2956    73 PDRAEALLELAQDYLKAG--LLDRAEEL--------LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL--- 139

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1039749675 393 gdcGKKVAETFYNMGSICFAKGELGEAIELLSK 425
Cdd:COG2956   140 ---GPENAHAYCELAELYLEQGDYDEAIEALEK 169
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 130-339 6.71e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.29  E-value: 6.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 130 CAQALANLAYGYLTLRGLPAQAKKHAEKARntlltwkrnttsdkdkkEILETLVRLYYTLGVAWLLQNHGKQAYIHLQKA 209
Cdd:COG3914    76 LLAALLELAALLLQALGRYEEALALYRRAL-----------------ALNPDNAEALFNLGNLLLALGRLEEALAALRRA 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 210 ErnmkelkELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAICdviLDKGHntselISLYEEIAQIEQLRKN 289
Cdd:COG3914   139 L-------ALNPDFA--------EAYLNLGEALRRLGRLEEAIAALRRALE---LDPDN-----AEALNNLGNALQDLGR 195

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1039749675 290 HKQAIQYLQQAYSIcvssfsevSPQTAEASALLAKAYAMSGASEYRDAVE 339
Cdd:COG3914   196 LEEAIAAYRRALEL--------DPDNADAHSNLLFALRQACDWEVYDRFE 237
TPR_12 pfam13424
Tetratricopeptide repeat;
238-303 7.15e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 7.15e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039749675 238 LGRASLAMHRMNLALAYFEKA--ICDVILDKGHNtsELISLYEEIAQIEQLRKNHKQAIQYLQQAYSI 303
Cdd:pfam13424   9 LAAVLRRLGRYDEALELLEKAleIARRLLGPDHP--LTATTLLNLGRLYLELGRYEEALELLERALAL 74
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 256-341 8.64e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 41.72  E-value: 8.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 256 EKAIcDVI-----LDKGHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSicvssfseVSPQTAEASALLAKAYAMSG 330
Cdd:PRK11788  158 QKAI-DVAerlekLGGDSLRVEIAHFYCELAQQALARGDLDAARALLKKALA--------ADPQCVRASILLGDLALAQG 228

                          90
                  ....*....|.
gi 1039749675 331 asEYRDAVEIY 341
Cdd:PRK11788  229 --DYAAAIEAL 237
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
277-430 1.13e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.76  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 277 YEEIAQIEQLRKNHKQAIQYLQQAYSIcvssfsevSPQTAEASALLAKAYAMSGasEYRDAVEiYFIRSIStyqtLGSED 356
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLG--RYEEALA-DYEQALE----LDPDD 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039749675 357 YETLTAIEdfcTWLIENGEKQEAYRLLKSTLnsgnfgDCGKKVAETFYNMGSICFAKGELGEAIELLSKCLMIQ 430
Cdd:COG0457    76 AEALNNLG---LALQALGRYEEALEDYDKAL------ELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
238-467 1.15e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.76  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 238 LGRASLAMHRMNLALAYFEKAIcdvILDKGHntselISLYEEIAQIEQLRKNHKQAIQYLQQAYSIcvssfsevSPQTAE 317
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKAL---ELDPDD-----AEALYNLGLAYLRLGRYEEALADYEQALEL--------DPDDAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 318 ASALLAKAYAMSGasEYRDAVEiYFIRSIStyqtLGSEDYETLTAIEDFctwLIENGEKQEAYRLLKSTLnsgnfgDCGK 397
Cdd:COG0457    78 ALNNLGLALQALG--RYEEALE-DYDKALE----LDPDDAEALYNLGLA---LLELGRYDEAIEAYERAL------ELDP 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 398 KVAETFYNMGSICFAKGELGEAIELLSKCLMIQSLVYGSEHIKSIETKSLLSLLQRWRLKETLEKNRKEA 467
Cdd:COG0457   142 DDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKL 211
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 130-300 1.24e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.02  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 130 CAQALANLAYGYLtLRGLPAQAKKHAEKARNTlltwkrnttsDKDKKEILETLVRLYYTLGvawllqnhgkqayiHLQKA 209
Cdd:COG4783     3 CAEALYALAQALL-LAGDYDEAEALLEKALEL----------DPDNPEAFALLGEILLQLG--------------DLDEA 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 210 ERNMKELKELNNGNIcgiqvsekDLTIALGRASLAMHRMNLALAYFEKAIcdvILDKGHntselISLYEEIAQIEQLRKN 289
Cdd:COG4783    58 IVLLHEALELDPDEP--------EARLNLGLALLKAGDYDEALALLEKAL---KLDPEH-----PEAYLRLARAYRALGR 121

                         170
                  ....*....|.
gi 1039749675 290 HKQAIQYLQQA 300
Cdd:COG4783   122 PDEAIAALEKA 132
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
182-341 1.45e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.38  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 182 LVRLYYTLGVAWLLQNHGKQAYIHLQKA-ERNMKELKELNNgnicgiqvsekdltiaLGRASLAMHRMNLALAYFEKAIc 260
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKAlELDPDDAEALYN----------------LGLAYLRLGRYEEALADYEQAL- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 261 dvildkgHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYSIcvssfsevSPQTAEASALLAKAYAMSGasEYRDAVEI 340
Cdd:COG0457    70 -------ELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL--------DPDDAEALYNLGLALLELG--RYDEAIEA 132


                  .
gi 1039749675 341 Y 341
Cdd:COG0457   133 Y 133
TPR_12 pfam13424
Tetratricopeptide repeat;
399-453 3.79e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.21  E-value: 3.79e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039749675 399 VAETFYNMGSICFAKGELGEAIELLSKCLMIQSLVYGSEHIKSIETKSLLSLLQR 453
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYL 56
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 227-341 4.13e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.02  E-value: 4.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 227 IQVSEKDLTIALGRASLAMHRMNLALAYFEKAIcdvILDKGHntselISLYEEIAQIEQLRKNHKQAIQYLQQAYSIcvs 306
Cdd:COG5010    49 KLAKAFAIESPSDNLYNKLGDFEESLALLEQAL---QLDPNN-----PELYYNLALLYSRSGDKDEAKEYYEKALAL--- 117

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1039749675 307 sfsevSPQTAEASALLAKAYAMSGasEYRDAVEIY 341
Cdd:COG5010   118 -----SPDNPNAYSNLAALLLSLG--QDDEAKAAL 145
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 236-341 4.86e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 4.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 236 IALGRASLAMHRMNLALAYFEKAIcdvildkgHNTSELISLYEEIAQIEQLRKNHKQAIQYLQQAYsicvssfsEVSPQT 315
Cdd:COG4783     8 YALAQALLLAGDYDEAEALLEKAL--------ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEAL--------ELDPDE 71

                          90       100
                  ....*....|....*....|....*.
gi 1039749675 316 AEASALLAKAYAMSGasEYRDAVEIY 341
Cdd:COG4783    72 PEARLNLGLALLKAG--DYDEALALL 95
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 271-427 5.66e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.09  E-value: 5.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749675 271 SELISLYEEIAQIEQLRKNHKQAIQYLQQAYsicvssfsEVSPQTAEASALLAKAYAMSGasEYRDAVEiYFIRSIStyq 350
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKAL--------ELDPDNPEAFALLGEILLQLG--DLDEAIV-LLHEALE--- 66

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039749675 351 tLGSEDYETLTAIedfCTWLIENGEKQEAYRLLKSTLnsgnfgDCGKKVAETFYNMGSICFAKGELGEAIELLSKCL 427
Cdd:COG4783    67 -LDPDEPEARLNL---GLALLKAGDYDEALALLEKAL------KLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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