NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1039761998|ref|XP_017174758|]
View 

opioid growth factor receptor isoform X1 [Mus musculus]

Protein Classification

OGFr_N and KLF9_13_N-like domain-containing protein( domain architecture ID 12056876)

OGFr_N and KLF9_13_N-like domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 55-262 5.35e-152

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


:

Pssm-ID: 461383  Cd Length: 208  Bit Score: 435.99  E-value: 5.35e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  55 DCNGDMCNLSFYKNEICFQPNGFLIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRE 134
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 135 RLVRAYELMLGFYGIQLEDRNTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHK 214
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1039761998 215 LPSVRQSALDYFLFAVRCRHQRRELVHFAWEHFKPRREFVWGPRDKLR 262
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 414-612 4.40e-14

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 75.88  E-value: 4.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 414 AEGDGVASNTQVQASALSPTPSE--CPESQKDGNGPEDPksqvGP--EDPKSQVgPEDPKSQVGPEDPKSqvgPEDPKgq 489
Cdd:PTZ00449  523 APGDKEGEEGEHEDSKESDEPKEggKPGETKEGEVGKKP----GPakEHKPSKI-PTLSKKPEFPKDPKH---PKDPE-- 592

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 490 vEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQS 569
Cdd:PTZ00449  593 -EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1039761998 570 QVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP 612
Cdd:PTZ00449  672 KEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
PHA03169 super family cl27451
hypothetical protein; Provisional
 263-527 4.92e-04

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PHA03169:

Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.04  E-value: 4.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 263 RFRPQTISRPLMGLGQADKDEGPgdPSQEAGTQGRtcgsgRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQRHEAKSPSPK 342
Cdd:PHA03169   34 GRRRGTAARAAKPAPPAPTTSGP--QVRAVAEQGH-----RQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPS 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 343 ESKKRKLEGNrqeqvpgEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEQPclvarvanevrkrRKVEEGAEGDGVASN 422
Cdd:PHA03169  107 PSGSAEELAS-------GLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAP-------------PESHNPSPNQQPSSF 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 423 TQVQASAlSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEdPKSQVGPEDPKGQVEPEDPKGQVGPE 502
Cdd:PHA03169  167 LQPSHED-SPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPT-PQQAPSPNTQQAVEHEDEPTEPEREG 244

                         250       260
                  ....*....|....*....|....*
gi 1039761998 503 DPkgQVGPEDPKGQVGPEDPKSQVG 527
Cdd:PHA03169  245 PP--FPGHRSHSYTVVGWKPSTRPG 267
 
Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 55-262 5.35e-152

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


Pssm-ID: 461383  Cd Length: 208  Bit Score: 435.99  E-value: 5.35e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  55 DCNGDMCNLSFYKNEICFQPNGFLIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRE 134
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 135 RLVRAYELMLGFYGIQLEDRNTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHK 214
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1039761998 215 LPSVRQSALDYFLFAVRCRHQRRELVHFAWEHFKPRREFVWGPRDKLR 262
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 414-612 4.40e-14

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 75.88  E-value: 4.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 414 AEGDGVASNTQVQASALSPTPSE--CPESQKDGNGPEDPksqvGP--EDPKSQVgPEDPKSQVGPEDPKSqvgPEDPKgq 489
Cdd:PTZ00449  523 APGDKEGEEGEHEDSKESDEPKEggKPGETKEGEVGKKP----GPakEHKPSKI-PTLSKKPEFPKDPKH---PKDPE-- 592

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 490 vEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQS 569
Cdd:PTZ00449  593 -EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1039761998 570 QVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP 612
Cdd:PTZ00449  672 KEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 424-588 4.64e-13

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 72.11  E-value: 4.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 424 QVQASALSPTPSECPESQKDG----NGPEDPKSQVGP--EDPKSQVG--PEDPKSQVGP--EDPKSQVG--PEDPKGQV- 490
Cdd:NF033839  309 EVKPEPETPKPEVKPQLEKPKpevkPQPEKPKPEVKPqlETPKPEVKpqPEKPKPEVKPqpEKPKPEVKpqPETPKPEVk 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 491 -EPEDPKGQVGP--EDPKGQVGP--EDPKGQVGP--EDPKSQVGP--EDPKSQV--EPEDPKSQVEPedpksQVEPEDPK 559
Cdd:NF033839  389 pQPEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVkpQPEKPKPEVKP-----QPETPKPE 463

                         170       180
                  ....*....|....*....|....*....
gi 1039761998 560 SQVGPEDPQSQVGPEQAASKSLGEDPDSD 588
Cdd:NF033839  464 VKPQPEKPKPEVKPQPEKPKPDNSKPQAD 492
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 470-586 6.24e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 58.38  E-value: 6.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 470 SQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSqvePEDPKSQVEPEDP 549
Cdd:NF038329  111 QQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQG---PAGKDGEAGAKGP 187

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1039761998 550 KSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPD 586
Cdd:NF038329  188 AGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGED 224
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 424-578 8.79e-08

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 55.16  E-value: 8.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 424 QVQASALSPTPSECPEsqkdgngPEDPKSQVGP--EDPKSQVGP--EDPKSQVGP--EDPKSQVGP--EDPKGQV--EPE 493
Cdd:NF033839  364 EVKPQPEKPKPEVKPQ-------PETPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVkpQPE 436

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 494 DPKGQVGP--EDPKGQVGPedpkgQVGPEDPKSQVGPEDPKSQVEPEDPKsqvePEDPKSQVEPEDPKSQVGPEDPQSQV 571
Cdd:NF033839  437 KPKPEVKPqpEKPKPEVKP-----QPETPKPEVKPQPEKPKPEVKPQPEK----PKPDNSKPQADDKKPSTPNNLSKDKQ 507


                  ....*..
gi 1039761998 572 GPEQAAS 578
Cdd:NF033839  508 PSNQAST 514
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 448-612 1.76e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 47.84  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 448 EDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPkGQVEPEDPKGQVGPEDPkgqvgPEDPKGQVGPEDPKSQVG 527
Cdd:NF033839  249 DNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEP-GNKKPSAPKPGMQPSPQ-----PEKKEVKPEPETPKPEVK 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 528 PEDPKSQVEPEDpksqvEPEDPKSQV-------------EPEDPKSQVGP--EDPQSQVGPEQAASKSlGEDPDSDTTGT 592
Cdd:NF033839  323 PQLEKPKPEVKP-----QPEKPKPEVkpqletpkpevkpQPEKPKPEVKPqpEKPKPEVKPQPETPKP-EVKPQPEKPKP 396

                         170       180
                  ....*....|....*....|
gi 1039761998 593 SMSESEELARIEASVEPPKP 612
Cdd:NF033839  397 EVKPQPEKPKPEVKPQPEKP 416
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
411-612 1.98e-05

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 47.37  E-value: 1.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 411 EEGAEGDGVASNTQVQASALSPTP------SECPESQKDGNGPEDPkSQVGPEDPKSQVGPEDPKSQVGPEDPKS----- 479
Cdd:pfam03546  31 ESDSEEETPAAKTPLQAKPSGKTPqvraasAPAKESPRKGAPPVPP-GKTGPAAAQAQAGKPEEDSESSSEESDSdgetp 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 480 ----------QVGPEDPKGQVEP-----EDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQV 544
Cdd:pfam03546 110 aaatlttspaQVKPLGKNSQVRPastvgKGPSGKGANPAPPGKAGSAAPLVQVGKKEEDSESSSEESDSEGEAPPAATQA 189

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039761998 545 EPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSmSESEELARIEASVEPPKP 612
Cdd:pfam03546 190 KPSGKILQVRPASGPAKGAAPAPPQKAGPVATQVKAERSKEDSESSEES-SDSEEEAPAAATPAQAKP 256
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 254-570 7.71e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 45.76  E-value: 7.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  254 VWGPRDKLRRFRPQTISRPLMGLGQADKDEGPGDPS-QEAGTQGRTCGSGRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQ 332
Cdd:TIGR00927  610 LWVKEQLSRRPVAKVMALGDLSKGDVAEAEHTGERTgEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAER 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  333 RHEAKSPSPKESKKRKLEGnrqEQVPGEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEqpclvarvaNEVRKRRKVEe 412
Cdd:TIGR00927  690 KGEQEGEGEIEAKEADHKG---ETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGE---------GEAEGKHEVE- 756

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  413 gAEGDGVASNTQVQASALSPTPSECPESQKDGNGpeDPKSQVGPEDPKSQVGPEDPKSQV-GPEDPKSQVGPEDPKGQVE 491
Cdd:TIGR00927  757 -TEGDRKETEHEGETEAEGKEDEDEGEIQAGEDG--EMKGDEGAEGKVEHEGETEAGEKDeHEGQSETQADDTEVKDETG 833

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039761998  492 PEDPKGQVGPEDPKGQVGPEDPKGQVGPEDpksqvgpEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQ 570
Cdd:TIGR00927  834 EQELNAENQGEAKQDEKGVDGGGGSDGGDS-------EEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 366-496 1.61e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 44.62  E-value: 1.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 366 VSEVEKIALNLEGCALSPTSQEPREAEqpclVARVANEVRKRRKVEEGAEGDGVASNTQVQASALSPTPSECPESQKDGN 445
Cdd:NF033838  358 VKEEAKEPRNEEKIKQAKAKVESKKAE----ATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAP 433

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1039761998 446 GPEDPKSQVGPEDPKSQVGPEDpKSQVGPEDPK--SQVGPEDPKGQVEPEDPK 496
Cdd:NF033838  434 KPEKPAEQPKAEKPADQQAEED-YARRSEEEYNrlTQQQPPKTEKPAQPSTPK 485
PHA03169 PHA03169
hypothetical protein; Provisional
 263-527 4.92e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.04  E-value: 4.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 263 RFRPQTISRPLMGLGQADKDEGPgdPSQEAGTQGRtcgsgRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQRHEAKSPSPK 342
Cdd:PHA03169   34 GRRRGTAARAAKPAPPAPTTSGP--QVRAVAEQGH-----RQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPS 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 343 ESKKRKLEGNrqeqvpgEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEQPclvarvanevrkrRKVEEGAEGDGVASN 422
Cdd:PHA03169  107 PSGSAEELAS-------GLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAP-------------PESHNPSPNQQPSSF 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 423 TQVQASAlSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEdPKSQVGPEDPKGQVEPEDPKGQVGPE 502
Cdd:PHA03169  167 LQPSHED-SPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPT-PQQAPSPNTQQAVEHEDEPTEPEREG 244

                         250       260
                  ....*....|....*....|....*
gi 1039761998 503 DPkgQVGPEDPKGQVGPEDPKSQVG 527
Cdd:PHA03169  245 PP--FPGHRSHSYTVVGWKPSTRPG 267
 
Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 55-262 5.35e-152

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


Pssm-ID: 461383  Cd Length: 208  Bit Score: 435.99  E-value: 5.35e-152
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  55 DCNGDMCNLSFYKNEICFQPNGFLIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRE 134
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 135 RLVRAYELMLGFYGIQLEDRNTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHK 214
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDEKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1039761998 215 LPSVRQSALDYFLFAVRCRHQRRELVHFAWEHFKPRREFVWGPRDKLR 262
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKLQ 208
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 414-612 4.40e-14

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 75.88  E-value: 4.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 414 AEGDGVASNTQVQASALSPTPSE--CPESQKDGNGPEDPksqvGP--EDPKSQVgPEDPKSQVGPEDPKSqvgPEDPKgq 489
Cdd:PTZ00449  523 APGDKEGEEGEHEDSKESDEPKEggKPGETKEGEVGKKP----GPakEHKPSKI-PTLSKKPEFPKDPKH---PKDPE-- 592

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 490 vEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQS 569
Cdd:PTZ00449  593 -EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1039761998 570 QVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP 612
Cdd:PTZ00449  672 KEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 424-588 4.64e-13

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 72.11  E-value: 4.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 424 QVQASALSPTPSECPESQKDG----NGPEDPKSQVGP--EDPKSQVG--PEDPKSQVGP--EDPKSQVG--PEDPKGQV- 490
Cdd:NF033839  309 EVKPEPETPKPEVKPQLEKPKpevkPQPEKPKPEVKPqlETPKPEVKpqPEKPKPEVKPqpEKPKPEVKpqPETPKPEVk 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 491 -EPEDPKGQVGP--EDPKGQVGP--EDPKGQVGP--EDPKSQVGP--EDPKSQV--EPEDPKSQVEPedpksQVEPEDPK 559
Cdd:NF033839  389 pQPEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVkpQPEKPKPEVKP-----QPETPKPE 463

                         170       180
                  ....*....|....*....|....*....
gi 1039761998 560 SQVGPEDPQSQVGPEQAASKSLGEDPDSD 588
Cdd:NF033839  464 VKPQPEKPKPEVKPQPEKPKPDNSKPQAD 492
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 382-611 5.16e-12

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 68.95  E-value: 5.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 382 SPTSQEPREAEQPclvarvanevrkrRKVEEGAEGDGVASNTQVQASALsPTPSECPESQKDGNGPEDPKSqvgPEDPKS 461
Cdd:PTZ00449  537 SKESDEPKEGGKP-------------GETKEGEVGKKPGPAKEHKPSKI-PTLSKKPEFPKDPKHPKDPEE---PKKPKR 599

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 462 QVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPK--------- 532
Cdd:PTZ00449  600 PRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKfkekfyddy 679

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 533 ------------------------SQVEPEDPKSQ---------VEPEDPKSQVEP-EDPKSQvGPEDPQSQVGPEQAAS 578
Cdd:PTZ00449  680 ldaaaksketkttvvldesfesilKETLPETPGTPfttprplppKLPRDEEFPFEPiGDPDAE-QPDDIEFFTPPEEERT 758

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1039761998 579 ---KSLGEDPDSDTTGTSMSESEELARIEASVEPPK 611
Cdd:PTZ00449  759 ffhETPADTPLPDILAEEFKEEDIHAETGEPDEAMK 794
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 470-586 6.24e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 58.38  E-value: 6.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 470 SQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSqvePEDPKSQVEPEDP 549
Cdd:NF038329  111 QQLKGDGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQG---PAGKDGEAGAKGP 187

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1039761998 550 KSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPD 586
Cdd:NF038329  188 AGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGED 224
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 424-578 8.79e-08

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 55.16  E-value: 8.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 424 QVQASALSPTPSECPEsqkdgngPEDPKSQVGP--EDPKSQVGP--EDPKSQVGP--EDPKSQVGP--EDPKGQV--EPE 493
Cdd:NF033839  364 EVKPQPEKPKPEVKPQ-------PETPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVKPqpEKPKPEVkpQPE 436

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 494 DPKGQVGP--EDPKGQVGPedpkgQVGPEDPKSQVGPEDPKSQVEPEDPKsqvePEDPKSQVEPEDPKSQVGPEDPQSQV 571
Cdd:NF033839  437 KPKPEVKPqpEKPKPEVKP-----QPETPKPEVKPQPEKPKPEVKPQPEK----PKPDNSKPQADDKKPSTPNNLSKDKQ 507


                  ....*..
gi 1039761998 572 GPEQAAS 578
Cdd:NF033839  508 PSNQAST 514
PHA03169 PHA03169
hypothetical protein; Provisional
 405-612 1.46e-06

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 50.74  E-value: 1.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 405 RKRRKVEEGAEGDGVASNTQVQASAL---SPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQV 481
Cdd:PHA03169   38 GTAARAAKPAPPAPTTSGPQVRAVAEqghRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASG 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 482 GPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDP-----KGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQvEPE 556
Cdd:PHA03169  118 LSPENTSGSSPESPASHSPPPSPPSHPGPHEPappesHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPP-QSE 196

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039761998 557 DPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEAsvEPPKP 612
Cdd:PHA03169  197 TPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGP--PFPGH 250
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 448-612 1.76e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 47.84  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 448 EDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPkGQVEPEDPKGQVGPEDPkgqvgPEDPKGQVGPEDPKSQVG 527
Cdd:NF033839  249 DNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEP-GNKKPSAPKPGMQPSPQ-----PEKKEVKPEPETPKPEVK 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 528 PEDPKSQVEPEDpksqvEPEDPKSQV-------------EPEDPKSQVGP--EDPQSQVGPEQAASKSlGEDPDSDTTGT 592
Cdd:NF033839  323 PQLEKPKPEVKP-----QPEKPKPEVkpqletpkpevkpQPEKPKPEVKPqpEKPKPEVKPQPETPKP-EVKPQPEKPKP 396

                         170       180
                  ....*....|....*....|
gi 1039761998 593 SMSESEELARIEASVEPPKP 612
Cdd:NF033839  397 EVKPQPEKPKPEVKPQPEKP 416
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
411-612 1.98e-05

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 47.37  E-value: 1.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 411 EEGAEGDGVASNTQVQASALSPTP------SECPESQKDGNGPEDPkSQVGPEDPKSQVGPEDPKSQVGPEDPKS----- 479
Cdd:pfam03546  31 ESDSEEETPAAKTPLQAKPSGKTPqvraasAPAKESPRKGAPPVPP-GKTGPAAAQAQAGKPEEDSESSSEESDSdgetp 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 480 ----------QVGPEDPKGQVEP-----EDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQV 544
Cdd:pfam03546 110 aaatlttspaQVKPLGKNSQVRPastvgKGPSGKGANPAPPGKAGSAAPLVQVGKKEEDSESSSEESDSEGEAPPAATQA 189

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039761998 545 EPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSmSESEELARIEASVEPPKP 612
Cdd:pfam03546 190 KPSGKILQVRPASGPAKGAAPAPPQKAGPVATQVKAERSKEDSESSEES-SDSEEEAPAAATPAQAKP 256
PHA03169 PHA03169
hypothetical protein; Provisional
 411-591 2.26e-05

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 47.27  E-value: 2.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 411 EEGAEGDGVASNTQVQASALSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPksqvGPEDPKSQVGPEDPKGQV 490
Cdd:PHA03169   92 PSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEP----APPESHNPSPNQQPSSFL 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 491 EPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQvEPEDPKSQVEPEDPKSQVGPEDPQS- 569
Cdd:PHA03169  168 QPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQ-QAPSPNTQQAVEHEDEPTEPEREGPp 246

                         170       180
                  ....*....|....*....|..
gi 1039761998 570 QVGPEQAASKSLGEDPDSDTTG 591
Cdd:PHA03169  247 FPGHRSHSYTVVGWKPSTRPGG 268
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 447-573 7.27e-05

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 43.66  E-value: 7.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 447 PEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQV 526
Cdd:pfam15140  49 PLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEMKPLGTAENILPLEAAREIHPLEAVGKIEPLQLVETI 128

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1039761998 527 GPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGP 573
Cdd:pfam15140 129 PKENESPEIHPLEGSQEIEPLEPVQLIEPLGEVEQIQPLETVPKENP 175
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 254-570 7.71e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 45.76  E-value: 7.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  254 VWGPRDKLRRFRPQTISRPLMGLGQADKDEGPGDPS-QEAGTQGRTCGSGRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQ 332
Cdd:TIGR00927  610 LWVKEQLSRRPVAKVMALGDLSKGDVAEAEHTGERTgEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAER 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  333 RHEAKSPSPKESKKRKLEGnrqEQVPGEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEqpclvarvaNEVRKRRKVEe 412
Cdd:TIGR00927  690 KGEQEGEGEIEAKEADHKG---ETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGE---------GEAEGKHEVE- 756

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  413 gAEGDGVASNTQVQASALSPTPSECPESQKDGNGpeDPKSQVGPEDPKSQVGPEDPKSQV-GPEDPKSQVGPEDPKGQVE 491
Cdd:TIGR00927  757 -TEGDRKETEHEGETEAEGKEDEDEGEIQAGEDG--EMKGDEGAEGKVEHEGETEAGEKDeHEGQSETQADDTEVKDETG 833

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039761998  492 PEDPKGQVGPEDPKGQVGPEDPKGQVGPEDpksqvgpEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQ 570
Cdd:TIGR00927  834 EQELNAENQGEAKQDEKGVDGGGGSDGGDS-------EEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQ 905
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 447-579 1.08e-04

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 43.28  E-value: 1.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 447 PEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQV 526
Cdd:pfam15140  40 DLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEMKPLGTAENILPLEAAREIHPLEAVGKI 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1039761998 527 GPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASK 579
Cdd:pfam15140 120 EPLQLVETIPKENESPEIHPLEGSQEIEPLEPVQLIEPLGEVEQIQPLETVPK 172
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 366-496 1.61e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 44.62  E-value: 1.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 366 VSEVEKIALNLEGCALSPTSQEPREAEqpclVARVANEVRKRRKVEEGAEGDGVASNTQVQASALSPTPSECPESQKDGN 445
Cdd:NF033838  358 VKEEAKEPRNEEKIKQAKAKVESKKAE----ATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAP 433

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1039761998 446 GPEDPKSQVGPEDPKSQVGPEDpKSQVGPEDPK--SQVGPEDPKGQVEPEDPK 496
Cdd:NF033838  434 KPEKPAEQPKAEKPADQQAEED-YARRSEEEYNrlTQQQPPKTEKPAQPSTPK 485
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 379-602 2.30e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 2.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 379 CALSPTSQEPREAEQPCLVARVANEVRKRRKVEEGAEGD-----GVASNTQVQASALSPTPSECPESQKDGNGPEDPKSQ 453
Cdd:PRK07764  586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPaapapAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 454 VGPEDPKsqVGPEDPKSQVGPEDPKSQVGPEDPKGQvePEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKS 533
Cdd:PRK07764  666 GDGWPAK--AGGAAPAAPPPAPAPAAPAAPAGAAPA--QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPL 741

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039761998 534 QVEPEDPKsqvEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTgTSMSESEELAR 602
Cdd:PRK07764  742 PPEPDDPP---DPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDD-EDRRDAEEVAM 806
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 456-612 3.23e-04

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 41.73  E-value: 3.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 456 PEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQV 535
Cdd:pfam15140   4 PSRPTSEIQPLKGVREIEPPQPGGKDDPLGAEEKKKDLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEI 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039761998 536 EPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDSDTTGTSMSESEELARIEASVEPPKP 612
Cdd:pfam15140  84 EPPQAASEMKPLGTAENILPLEAAREIHPLEAVGKIEPLQLVETIPKENESPEIHPLEGSQEIEPLEPVQLIEPLGE 160
PHA03169 PHA03169
hypothetical protein; Provisional
 263-527 4.92e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.04  E-value: 4.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 263 RFRPQTISRPLMGLGQADKDEGPgdPSQEAGTQGRtcgsgRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQRHEAKSPSPK 342
Cdd:PHA03169   34 GRRRGTAARAAKPAPPAPTTSGP--QVRAVAEQGH-----RQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPS 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 343 ESKKRKLEGNrqeqvpgEPDPQGVSEVEKIALNLEGCALSPTSQEPREAEQPclvarvanevrkrRKVEEGAEGDGVASN 422
Cdd:PHA03169  107 PSGSAEELAS-------GLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAP-------------PESHNPSPNQQPSSF 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 423 TQVQASAlSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEdPKSQVGPEDPKGQVEPEDPKGQVGPE 502
Cdd:PHA03169  167 LQPSHED-SPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPT-PQQAPSPNTQQAVEHEDEPTEPEREG 244

                         250       260
                  ....*....|....*....|....*
gi 1039761998 503 DPkgQVGPEDPKGQVGPEDPKSQVG 527
Cdd:PHA03169  245 PP--FPGHRSHSYTVVGWKPSTRPG 267
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 434-580 7.86e-04

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 40.58  E-value: 7.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 434 PSECPESQKDGN-GPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPED 512
Cdd:pfam15140  17 VREIEPPQPGGKdDPLGAEEKKKDLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEMKPLG 96

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039761998 513 PKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKS 580
Cdd:pfam15140  97 TAENILPLEAAREIHPLEAVGKIEPLQLVETIPKENESPEIHPLEGSQEIEPLEPVQLIEPLGEVEQI 164
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 446-574 8.66e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.38  E-value: 8.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  446 GPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQ 525
Cdd:PRK10263   365 GPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAG 444

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039761998  526 vGPEDPKSQVEPEDPKSQVEPEDPKSQ-VEPEDPKSQVGPEDPQSQVGPE 574
Cdd:PRK10263   445 -NAWQAEEQQSTFAPQSTYQTEQTYQQpAAQEPLYQQPQPVEQQPVVEPE 493
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 410-592 2.99e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 40.35  E-value: 2.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 410 VEEGAEGDGVASNTQVQASALSPTPsecPESQKDGNGPEDPKSQVGPEDPK-SQVGPEDPKSQVGPEDPKSQVGPEDPKg 488
Cdd:PRK13108  292 VDEALEREPAELAAAAVASAASAVG---PVGPGEPNQPDDVAEAVKAEVAEvTDEVAAESVVQVADRDGESTPAVEETS- 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 489 qvEPEDPKGQvgPEDPKGQvGPEDPKgqvgPEDPKSQVGPEDPKSQvEPEDPkSQVEPEDPksqvEPEDPKSQVGPEDPQ 568
Cdd:PRK13108  368 --EADIEREQ--PGDLAGQ-APAAHQ----VDAEAASAAPEEPAAL-ASEAH-DETEPEVP----EKAAPIPDPAKPDEL 432

                         170       180
                  ....*....|....*....|....
gi 1039761998 569 SQVGPEQAASKSLGEDPDSDTTGT 592
Cdd:PRK13108  433 AVAGPGDDPAEPDGIRRQDDFSSR 456
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 447-578 3.88e-03

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 38.65  E-value: 3.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 447 PEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQV 526
Cdd:pfam15140  13 PLKGVREIEPPQPGGKDDPLGAEEKKKDLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIEPPQAASEM 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1039761998 527 GPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAAS 578
Cdd:pfam15140  93 KPLGTAENILPLEAAREIHPLEAVGKIEPLQLVETIPKENESPEIHPLEGSQ 144
DUF4573 pfam15140
Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins ...
 430-578 5.48e-03

Domain of unknown function (DUF4573); This family of proteins is found in eukaryotes. Proteins in this family are typically approximately 360 amino acids in length.


Pssm-ID: 434493 [Multi-domain]  Cd Length: 176  Bit Score: 38.27  E-value: 5.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 430 LSPTPSECPESQKDGNGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVG 509
Cdd:pfam15140   5 SRPTSEIQPLKGVREIEPPQPGGKDDPLGAEEKKKDLRAVTEVEPLKGVAEIEPLGPVSEIQPLRAVSERDPLGAVEEIE 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039761998 510 PEDPKGQVGPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAAS 578
Cdd:pfam15140  85 PPQAASEMKPLGTAENILPLEAAREIHPLEAVGKIEPLQLVETIPKENESPEIHPLEGSQEIEPLEPVQ 153
FAM47 pfam14642
FAM47 family; The function of this Chordate family of proteins is not known.
 465-562 5.98e-03

FAM47 family; The function of this Chordate family of proteins is not known.


Pssm-ID: 405345 [Multi-domain]  Cd Length: 257  Bit Score: 39.09  E-value: 5.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 465 PEDPKSQVgpEDPKSQVGPEdpKGQVEPEDPK----GQVGPEDPKGQVG--PEDPkgqvgPEDPKSQVGPEDPK---SQV 535
Cdd:pfam14642 152 PLDPERKL--EDAGSCEGQE--KTTDEPTEPGkypcGEFSPRPPETRVSclPPEP-----PKTPVSSLRPEPPEtgvSHL 222

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1039761998 536 EPEDPKSQVE------PEDPKSQVEPEDPKSQV 562
Cdd:pfam14642 223 RPQPPKTQVSslhlepPETGVSHLRPEPPKTQV 255
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 432-612 8.44e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 39.38  E-value: 8.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  432 PTPSECPESQKDGNGPEDPKS--QVGPEDPKSQVGPEDPKSQVGPEDPKSQVGPEDPKGQVEPEDPK--GQVGPEDPKGQ 507
Cdd:PHA03307    73 PGPGTEAPANESRSTPTWSLStlAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRpvGSPGPPPAASP 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998  508 VGPEDPKGQVgPEDPKSQVGPEDPKSQVEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQVGPEQAASKSLGEDPDS 587
Cdd:PHA03307   153 PAAGASPAAV-ASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADD 231

                          170       180
                   ....*....|....*....|....*
gi 1039761998  588 DTTGTSMSESEELARIEASVEPPKP 612
Cdd:PHA03307   232 AGASSSDSSSSESSGCGWGPENECP 256
NESP55 pfam06390
Neuroendocrine-specific golgi protein P55 (NESP55); This family consists of several mammalian ...
 412-570 9.48e-03

Neuroendocrine-specific golgi protein P55 (NESP55); This family consists of several mammalian neuroendocrine-specific golgi protein P55 (NESP55) sequences. NESP55 is a novel member of the chromogranin family and is a soluble, acidic, heat-stable secretory protein that is expressed exclusively in endocrine and nervous tissues, although less widely than chromogranins.


Pssm-ID: 115071 [Multi-domain]  Cd Length: 261  Bit Score: 38.31  E-value: 9.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761998 412 EGAEGDGVASNTQVQASALSPtpsECPESQKDGNGPEDPKSQvgpeDPKSQVGPEDpKSQVGPEDPKSQVGPEDPkgQVE 491
Cdd:pfam06390  82 EPSEPESDHEDEDFEPELARP---ECLEYDEDDFDTETDSET----EPESDIESET-EFETEPETEPDTAPTTEP--ETE 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039761998 492 PEDPKGQVGPEDPKGQVGPEDPKGQVGPEDPKSQVGPEDPKSQvEPEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQSQ 570
Cdd:pfam06390 152 PEDEPGPVVPKGATFHQSLTERLHALKLQSADASPRRAPPSTQ-EPESAREGEEPERGPLDKDPRDPEEEEEEKEEEKQ 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH