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Conserved domains on  [gi|1191076457|ref|XP_020917161|]
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LOW QUALITY PROTEIN: uncharacterized protein LOC110254495 [Exaiptasia diaphana]

Protein Classification

ankyrin repeat domain-containing protein( domain architecture ID 11429852)

ankyrin repeat domain-containing protein; ANK proteins mediate specific protein-protein interactions without necessarily recognizing specific primary sequences which allows for one ankyrin repeat domain to recognize and bind to a variety of intracellular substrates and may be involved in a wide array of functions

Gene Ontology:  GO:0005515
PubMed:  17176038
SCOP:  4000366

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
68-237 3.52e-18

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 83.46  E-value: 3.52e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457  68 MILLDAVSKCRLRQLRLLLDAGINVNSKDfNTGQTALIRATYLEDSKLrricTAMLINYGAKVKVADHMKRTALSWAcll 147
Cdd:COG0666    89 TLLHAAARNGDLEIVKLLLEAGADVNARD-KDGETPLHLAAYNGNLEI----VKLLLEAGADVNAQDNDGNTPLHLA--- 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457 148 ARENSLKIFQskpELdLAY----DSVDSDGNTNLLLACMSGNVNVVRTIAKsfhrNRLDVNRKNNQGETALSVAVKQANR 223
Cdd:COG0666   161 AANGNLEIVK---LL-LEAgadvNARDNDGETPLHLAAENGHLEIVKLLLE----AGADVNAKDNDGKTALDLAAENGNL 232

                         170
                  ....*....|....
gi 1191076457 224 DMIIILIDIAHVTN 237
Cdd:COG0666   233 EIVKLLLEAGADLN 246
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
68-237 3.52e-18

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 83.46  E-value: 3.52e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457  68 MILLDAVSKCRLRQLRLLLDAGINVNSKDfNTGQTALIRATYLEDSKLrricTAMLINYGAKVKVADHMKRTALSWAcll 147
Cdd:COG0666    89 TLLHAAARNGDLEIVKLLLEAGADVNARD-KDGETPLHLAAYNGNLEI----VKLLLEAGADVNAQDNDGNTPLHLA--- 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457 148 ARENSLKIFQskpELdLAY----DSVDSDGNTNLLLACMSGNVNVVRTIAKsfhrNRLDVNRKNNQGETALSVAVKQANR 223
Cdd:COG0666   161 AANGNLEIVK---LL-LEAgadvNARDNDGETPLHLAAENGHLEIVKLLLE----AGADVNAKDNDGKTALDLAAENGNL 232

                         170
                  ....*....|....
gi 1191076457 224 DMIIILIDIAHVTN 237
Cdd:COG0666   233 EIVKLLLEAGADLN 246
Ank_2 pfam12796
Ankyrin repeats (3 copies);
123-207 3.40e-06

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 44.72  E-value: 3.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457 123 LINYGAKVKVADHMKRTALSWACLLARENSLKIFQSKPELDlaydsVDSDGNTNLLLACMSGNVNVVRTIAKsfhrNRLD 202
Cdd:pfam12796  16 LLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVN-----LKDNGRTALHYAARSGHLEIVKLLLE----KGAD 86


                  ....*
gi 1191076457 203 VNRKN 207
Cdd:pfam12796  87 INVKD 91
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 99-230 8.83e-04

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 41.01  E-value: 8.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457  99 TGQTALiratYLEDSKLRRICTAMLINYGAKVKVADHMKRTALsWACLLARENslKIFQSkpeldLAYDSVDSDGNTN-- 176
Cdd:PLN03192  557 KGRTPL----HIAASKGYEDCVLVLLKHACNVHIRDANGNTAL-WNAISAKHH--KIFRI-----LYHFASISDPHAAgd 624

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1191076457 177 -LLLACMSGNVNVVRTIAKsfhrNRLDVNRKNNQGETALSVAVKQANRDMIIILI 230
Cdd:PLN03192  625 lLCTAAKRNDLTAMKELLK----QGLNVDSEDHQGATALQVAMAEDHVDMVRLLI 675
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
68-237 3.52e-18

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 83.46  E-value: 3.52e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457  68 MILLDAVSKCRLRQLRLLLDAGINVNSKDfNTGQTALIRATYLEDSKLrricTAMLINYGAKVKVADHMKRTALSWAcll 147
Cdd:COG0666    89 TLLHAAARNGDLEIVKLLLEAGADVNARD-KDGETPLHLAAYNGNLEI----VKLLLEAGADVNAQDNDGNTPLHLA--- 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457 148 ARENSLKIFQskpELdLAY----DSVDSDGNTNLLLACMSGNVNVVRTIAKsfhrNRLDVNRKNNQGETALSVAVKQANR 223
Cdd:COG0666   161 AANGNLEIVK---LL-LEAgadvNARDNDGETPLHLAAENGHLEIVKLLLE----AGADVNAKDNDGKTALDLAAENGNL 232

                         170
                  ....*....|....
gi 1191076457 224 DMIIILIDIAHVTN 237
Cdd:COG0666   233 EIVKLLLEAGADLN 246
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
68-243 1.05e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 79.23  E-value: 1.05e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457  68 MILLDAVSKCRLRQLRLLLDAGINVNSKDFNtGQTALIRATYLEDSKLRRictaMLINYGAKVKVADHMKRTALSWAcll 147
Cdd:COG0666    56 LLLLAAALAGDLLVALLLLAAGADINAKDDG-GNTLLHAAARNGDLEIVK----LLLEAGADVNARDKDGETPLHLA--- 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457 148 ARENSLKIFqskpELDLAY----DSVDSDGNTNLLLACMSGNVNVVRTIAKsfhrNRLDVNRKNNQGETALSVAVKQANR 223
Cdd:COG0666   128 AYNGNLEIV----KLLLEAgadvNAQDNDGNTPLHLAAANGNLEIVKLLLE----AGADVNARDNDGETPLHLAAENGHL 199

                         170       180
                  ....*....|....*....|....
gi 1191076457 224 DMIIILI----DIAHVTNVGSYPI 243
Cdd:COG0666   200 EIVKLLLeagaDVNAKDNDGKTAL 223
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
87-208 1.25e-07

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 52.26  E-value: 1.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457  87 DAGINVNSKDfNTGQTALIRATYLEDSKLrricTAMLINYGAKVKVADHMKRTALSWACLLARENSLKIFQSKPELDLAy 166
Cdd:COG0666   174 EAGADVNARD-NDGETPLHLAAENGHLEI----VKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNA- 247

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1191076457 167 dsVDSDGNTNLLLACMSGNVNVVRTIAKSFHRNRLDVNRKNN 208
Cdd:COG0666   248 --KDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLT 287
Ank_2 pfam12796
Ankyrin repeats (3 copies);
123-207 3.40e-06

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 44.72  E-value: 3.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457 123 LINYGAKVKVADHMKRTALSWACLLARENSLKIFQSKPELDlaydsVDSDGNTNLLLACMSGNVNVVRTIAKsfhrNRLD 202
Cdd:pfam12796  16 LLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVN-----LKDNGRTALHYAARSGHLEIVKLLLE----KGAD 86


                  ....*
gi 1191076457 203 VNRKN 207
Cdd:pfam12796  87 INVKD 91
Ank_2 pfam12796
Ankyrin repeats (3 copies);
141-231 4.60e-06

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 44.34  E-value: 4.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457 141 LSWAcllARENSLKIFQSKPELDLAYDSVDSDGNTNLLLACMSGNVNVVRTIAKSFHRNRldvnrkNNQGETALSVAVKQ 220
Cdd:pfam12796   1 LHLA---AKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNL------KDNGRTALHYAARS 71

                          90
                  ....*....|.
gi 1191076457 221 ANRDMIIILID 231
Cdd:pfam12796  72 GHLEIVKLLLE 82
Ank_4 pfam13637
Ankyrin repeats (many copies);
173-230 7.26e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 42.65  E-value: 7.26e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1191076457 173 GNTNLLLACMSGNVNVVRTIAKsfhrNRLDVNRKNNQGETALSVAVKQANRDMIIILI 230
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLLLE----KGADINAVDGNGETALHFAASNGNVEVLKLLL 54
Ank_2 pfam12796
Ankyrin repeats (3 copies);
177-240 1.73e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 40.10  E-value: 1.73e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1191076457 177 LLLACMSGNVNVVrtiaKSFHRNRLDVNRKNNQGETALSVAVKQANRDMIIILIDIAHVTNVGS 240
Cdd:pfam12796   1 LHLAAKNGNLELV----KLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNLKDN 60
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 99-230 8.83e-04

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 41.01  E-value: 8.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1191076457  99 TGQTALiratYLEDSKLRRICTAMLINYGAKVKVADHMKRTALsWACLLARENslKIFQSkpeldLAYDSVDSDGNTN-- 176
Cdd:PLN03192  557 KGRTPL----HIAASKGYEDCVLVLLKHACNVHIRDANGNTAL-WNAISAKHH--KIFRI-----LYHFASISDPHAAgd 624

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1191076457 177 -LLLACMSGNVNVVRTIAKsfhrNRLDVNRKNNQGETALSVAVKQANRDMIIILI 230
Cdd:PLN03192  625 lLCTAAKRNDLTAMKELLK----QGLNVDSEDHQGATALQVAMAEDHVDMVRLLI 675
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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