|
Name |
Accession |
Description |
Interval |
E-value |
| CAP_GLY |
pfam01302 |
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ... |
205-269 |
5.94e-36 |
|
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 460154 [Multi-domain] Cd Length: 65 Bit Score: 129.83 E-value: 5.94e-36
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1207177222 205 VGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKV 269
Cdd:pfam01302 1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
|
|
| CAP_GLY |
smart01052 |
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ... |
205-269 |
5.28e-29 |
|
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 214997 [Multi-domain] Cd Length: 68 Bit Score: 110.37 E-value: 5.28e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207177222 205 VGDRVLVGGT-KTGVVRYVGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCPPKFGLFAPIHKV 269
Cdd:smart01052 1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKV 67
|
|
| CAP_GLY |
pfam01302 |
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ... |
74-138 |
6.09e-28 |
|
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 460154 [Multi-domain] Cd Length: 65 Bit Score: 107.10 E-value: 6.09e-28
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1207177222 74 VGERVWVNGVKPGVIAYLGETQFSPGQWAGVVLNDLVGKNDGSVNGVRYFECQALQGIFTRPSKL 138
Cdd:pfam01302 1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
|
|
| CAP_GLY |
smart01052 |
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ... |
74-139 |
9.46e-25 |
|
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 214997 [Multi-domain] Cd Length: 68 Bit Score: 98.04 E-value: 9.46e-25
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207177222 74 VGERVWVNG-VKPGVIAYLGETQFSPGQWAGVVL-NDLVGKNDGSVNGVRYFECQALQGIFTRPSKLT 139
Cdd:smart01052 1 VGDRVEVGGgGRRGTVRYVGPTPFAPGVWVGVELdEPLRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
345-886 |
5.86e-16 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 83.24 E-value: 5.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 345 LKEKQQHIEQLLAERDLE------RAEVAKATSHICEVEKELAALKAR-----HLQYATETESNLQQVRAMLASTQK--- 410
Cdd:pfam15921 262 LQQHQDRIEQLISEHEVEitglteKASSARSQANSIQSQLEIIQEQARnqnsmYMRQLSDLESTVSQLRSELREAKRmye 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 411 DKMElanqlEEEKRKV----EDLQFRVEEESITKGDLEVRGRLQPTPTRLGKSVKQTTVEEKTR-------------VMQ 473
Cdd:pfam15921 342 DKIE-----ELEKQLVlansELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNkrlwdrdtgnsitIDH 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 474 LEEELALRKAEVEELQVRFQRGSSGSATDAEDGEPGITSETlvlreqllsvgrERREESSQLRERYEASLSTSQKEIERL 553
Cdd:pfam15921 417 LRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKN------------ESLEKVSSLTAQLESTKEMLRKVVEEL 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 554 ---KAITERQGQEISDLKQRLQQATREnMEMMDSWKAKLDALVGDHQRALEELKA------SLTTDCGSGEINGGEGEGS 624
Cdd:pfam15921 485 takKMTLESSERTVSDLTASLQEKERA-IEATNAEITKLRSRVDLKLQELQHLKNegdhlrNVQTECEALKLQMAEKDKV 563
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 625 LPEMRAALEGLKmehqleleNLKAKHEIDAAVMAKEREDLRSRLQELRDQLEDseenWKIQVETKSNQhtleIKEVSEKL 704
Cdd:pfam15921 564 IEILRQQIENMT--------QLVGQHGRTAGAMQVEKAQLEKEINDRRLELQE----FKILKDKKDAK----IRELEARV 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 705 QKAELRIVDLDKSQEEREKVNQLLKEQ--LMLAEKKMV---------DYEALQKAEAQSRAEILSLQEKLRVTENRLQAv 773
Cdd:pfam15921 628 SDLELEKVKLVNAGSERLRAVKDIKQErdQLLNEVKTSrnelnslseDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQS- 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 774 EADHTTQDVNMIENNDNSDEKVKLKQnveetlekltkrEKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRL 853
Cdd:pfam15921 707 ELEQTRNTLKSMEGSDGHAMKVAMGM------------QKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKL 774
|
570 580 590
....*....|....*....|....*....|....
gi 1207177222 854 EAELETMTKKSHDASGQL-VNISQELLKKERSLN 886
Cdd:pfam15921 775 SQELSTVATEKNKMAGELeVLRSQERRLKEKVAN 808
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
341-976 |
3.88e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.49 E-value: 3.88e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 341 LQEALKEKQQHIEQLLAERDLERAEVAKAtshicevEKELAALKARhlqyATETESNLQQVRAMLASTQKDKMELANQLE 420
Cdd:TIGR02168 335 LAEELAELEEKLEELKEELESLEAELEEL-------EAELEELESR----LEELEEQLETLRSKVAQLELQIASLNNEIE 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 421 EEKRKVEDLQFRVEEESITKGDLE---VRGRLQPTPTRLGKsVKQTTVEEKTRVMQLEEELALRKAEVEELQVRFQ---- 493
Cdd:TIGR02168 404 RLEARLERLEDRRERLQQEIEELLkklEEAELKELQAELEE-LEEELEELQEELERLEEALEELREELEEAEQALDaaer 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 494 --RGSSGSATDAEDGE-----PGITSETLVLREQLLSVGRERREESSQLRERYEASLSTSQKeiERLKAIT----ERQGQ 562
Cdd:TIGR02168 483 elAQLQARLDSLERLQenlegFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALG--GRLQAVVvenlNAAKK 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 563 EISDLKQrlQQATRENMEMMDSWKAKLDALVGDHQRALEELKASLTTDCGSGEinggegegslPEMRAALEGLkmehqle 642
Cdd:TIGR02168 561 AIAFLKQ--NELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD----------PKLRKALSYL------- 621
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 643 LENLKAKHEIDAAVMAKEREDLRSRLQELRDQL---------EDSEENWKIQvETKSnqhtlEIKEVSEKLQKAELRIVD 713
Cdd:TIGR02168 622 LGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLvrpggvitgGSAKTNSSIL-ERRR-----EIEELEEKIEELEEKIAE 695
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 714 LDKSQEEREKVNQLLKEQLMLAEKKMVDYE----ALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENND 789
Cdd:TIGR02168 696 LEKALAELRKELEELEEELEQLRKELEELSrqisALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 790 NSDEKVKLKQNVEETLEKLtkrEKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASG 869
Cdd:TIGR02168 776 ELAEAEAEIEELEAQIEQL---KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 870 QLVNISQELLKKERSLNElrvllLESPRHSAGVDRDlSREVHRAEWRMKEQKLQDDIKTLREKLLLLGRERLSPDHRRys 949
Cdd:TIGR02168 853 DIESLAAEIEELEELIEE-----LESELEALLNERA-SLEEALALLRSELEELSEELRELESKRSELRRELEELREKL-- 924
|
650 660
....*....|....*....|....*..
gi 1207177222 950 mmdpSASDTEVARLRQRLLNTEDALRN 976
Cdd:TIGR02168 925 ----AQLELRLEGLEVRIDNLQERLSE 947
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
203-263 |
7.02e-15 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 79.34 E-value: 7.02e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1207177222 203 LKVGDRVLVGGTKtGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLF 263
Cdd:COG5244 4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
74-135 |
2.33e-12 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 70.87 E-value: 2.33e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1207177222 74 VGERVWVNGVKpGVIAYLGETQFSPGQWAGVVLNDLVGKNDGSVNGVRYFECQALQGIFTRP 135
Cdd:COG5244 6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
340-967 |
7.01e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.97 E-value: 7.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 340 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATEtesnLQQVRAMLASTQKDKMELANQL 419
Cdd:COG1196 243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE----LARLEQDIARLEERRRELEERL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 420 EEEKRKVEDLQFRVEEEsitkgdlevrgrlqptptrlgksvKQTTVEEKTRVMQLEEELALRKAEVEELQvrfqrgssgs 499
Cdd:COG1196 319 EELEEELAELEEELEEL------------------------EEELEELEEELEEAEEELEEAEAELAEAE---------- 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 500 atdaedgepgitsetlvlrEQLLSVGRERREESSQLRERYEASLSTSQKEIERLKAITERQgQEISDLKQRLQQATRENM 579
Cdd:COG1196 365 -------------------EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE-EAEEALLERLERLEEELE 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 580 EMMDSWKAKLDALVGDHQRALEELKAslttdcgsgeinggegegslpemRAALEGLKMEHQLELENLKAKHEIDAAVMAK 659
Cdd:COG1196 425 ELEEALAELEEEEEEEEEALEEAAEE-----------------------EAELEEEEEALLELLAELLEEAALLEAALAE 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 660 EREDLRSRLQELRDQLEDSEENWKIQVETKSNQHTLEIKEVSEKLqkAELRIVDLDKSQEEREKVNQLLKEQLMLAEKKM 739
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV--AVLIGVEAAYEAALEAALAAALQNIVVEDDEVA 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 740 VDYEALQKAEAQSRAEILSLqEKLRVTENRLQAVEADHTTQDVNMIEnNDNSDEKVKLKQNVEETLEKltkrekevSTLT 819
Cdd:COG1196 560 AAAIEYLKAAKAGRATFLPL-DKIRARAALAAALARGAIGAAVDLVA-SDLREADARYYVLGDTLLGR--------TLVA 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 820 TQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLLLESPRHS 899
Cdd:COG1196 630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207177222 900 AGVDRDLSREVHRAEwRMKEQKLQDDIKTLREKLLLLGRERLSPDHRRYSMMDPSASDTEVARLRQRL 967
Cdd:COG1196 710 AEAEEERLEEELEEE-ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
344-929 |
7.90e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.58 E-value: 7.90e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 344 ALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLqyatETESNLQQVRAMLASTQKDKMELANQLEEEK 423
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE----ELELELEEAQAEEYELLAELARLEQDIARLE 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 424 RKVEDLQFRVEEESITKGDLEVRGRLQptptrlgksvKQTTVEEKTRVMQLEEELALRKAEVEELQVRFQRGSSGSATDA 503
Cdd:COG1196 309 ERRRELEERLEELEEELAELEEELEEL----------EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 504 EdgepgitsETLVLREQLLSVGRERREESSQLRERyEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATRENMEMmD 583
Cdd:COG1196 379 E--------ELEELAEELLEALRAAAELAAQLEEL-EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA-A 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 584 SWKAKLDALVGDHQRALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVMAKERED 663
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 664 LRSRLQELRDQLEDSEENWKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEkkMVDYE 743
Cdd:COG1196 529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV--DLVAS 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 744 ALQKAEAQSRAEILSLQEKLRVTENRLQAVEAdhttqdvnmIENNDNSDEKVKLKQNVEETLEKLTKREKEvstltTQVD 823
Cdd:COG1196 607 DLREADARYYVLGDTLLGRTLVAARLEAALRR---------AVTLAGRLREVTLEGEGGSAGGSLTGGSRR-----ELLA 672
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 824 ALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLLLESPRH-SAGV 902
Cdd:COG1196 673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELlEEEA 752
|
570 580
....*....|....*....|....*..
gi 1207177222 903 DRDLSREVHRAEWRMKEQKLQDDIKTL 929
Cdd:COG1196 753 LEELPEPPDLEELERELERLEREIEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
339-863 |
2.51e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.04 E-value: 2.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 339 TALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQKDKMELANQ 418
Cdd:COG1196 284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 419 LEEEKRKVEDLQFRVEE-ESITKGDLEVRGRLQPTPTRLGKSVKQTTVEEKTRVMQLEEELALRKAEVEELQVRFQRGSS 497
Cdd:COG1196 364 EEALLEAEAELAEAEEElEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 498 GSATDAEDGEpgITSETLVLREQLLSVGRERREESSQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATRE 577
Cdd:COG1196 444 LEEAAEEEAE--LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 578 NME---MMDSWKAKLDALVGDhqRALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDA 654
Cdd:COG1196 522 LAGavaVLIGVEAAYEAALEA--ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 655 AVMA----KEREDLRSRLQELRDQLEDSEENWKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKE 730
Cdd:COG1196 600 AVDLvasdLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 731 QLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENNDnsDEKVKLKQNVEETLEKLTK 810
Cdd:COG1196 680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL--EELLEEEELLEEEALEELP 757
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1207177222 811 REKEVSTLTTQVDALKTQITAL---------------EEKVRLGEKTADgLIKEKTRLE---AELETMTKK 863
Cdd:COG1196 758 EPPDLEELERELERLEREIEALgpvnllaieeyeeleERYDFLSEQRED-LEEARETLEeaiEEIDRETRE 827
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
329-891 |
1.02e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 65.86 E-value: 1.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 329 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKArHLQYATETESNLQQVRAMLAST 408
Cdd:PRK03918 179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE-LKEEIEELEKELESLEGSKRKL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 409 QKDKMELANQLEEEKRKVEDLQFRVEE-ESITKGDLEVRgrlqptptRLGKSVKQTTVEEKtrvmQLEEELALRKAEVEE 487
Cdd:PRK03918 258 EEKIRELEERIEELKKEIEELEEKVKElKELKEKAEEYI--------KLSEFYEEYLDELR----EIEKRLSRLEEEING 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 488 LQVRFQRGSSGSATDAEdgepgITSETLVLREQLlsvgrERREESSQLRERYEASLstsqKEIERLKAitERQGQEISDL 567
Cdd:PRK03918 326 IEERIKELEEKEERLEE-----LKKKLKELEKRL-----EELEERHELYEEAKAKK----EELERLKK--RLTGLTPEKL 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 568 KQRLQQATRENMEMMD------SWKAKLDALVGDHQRALEELKASlttdcgsgeinggegEGSLPEMRAALEglkmEHql 641
Cdd:PRK03918 390 EKELEELEKAKEEIEEeiskitARIGELKKEIKELKKAIEELKKA---------------KGKCPVCGRELT----EE-- 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 642 ELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLEDSEENWKIQVETKSNQHTLE-IKEVSEKLQKAELRivDLDKSQEE 720
Cdd:PRK03918 449 HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEqLKELEEKLKKYNLE--ELEKKAEE 526
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 721 REKVNQL---LKEQLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAV------EADHTTQDVNMIENNDNS 791
Cdd:PRK03918 527 YEKLKEKlikLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesveELEERLKELEPFYNEYLE 606
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 792 ------------DEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITalEEKVRLGEKTADGLIKEKTRLEAELET 859
Cdd:PRK03918 607 lkdaekelereeKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEE 684
|
570 580 590
....*....|....*....|....*....|..
gi 1207177222 860 MTKKSHDASGQLVNISQELLKKERSLNELRVL 891
Cdd:PRK03918 685 LEKRREEIKKTLEKLKEELEEREKAKKELEKL 716
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
332-889 |
2.16e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.16 E-value: 2.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 332 ARKISGTTALQEALKEKQqhiEQLLAERDLERAEVAK-ATSHICEVEKELAALKARHLQYATETESNLQQVRA--MLAST 408
Cdd:PTZ00121 1223 AKKAEAVKKAEEAKKDAE---EAKKAEEERNNEEIRKfEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAdeAKKAE 1299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 409 QKDKMELANQLEEEKRKVEDLQFRVEE-----ESITKGDLEVRGRLQPTPTRLGKSVKQT-TVEEKTRVMQLEEELALRK 482
Cdd:PTZ00121 1300 EKKKADEAKKKAEEAKKADEAKKKAEEakkkaDAAKKKAEEAKKAAEAAKAEAEAAADEAeAAEEKAEAAEKKKEEAKKK 1379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 483 AEVEELQVRFQRGSSGSATDAEdgEPGITSETLVLREQLLSVGRERREESSQLRERYEASLSTSQK---EIERLKAITER 559
Cdd:PTZ00121 1380 ADAAKKKAEEKKKADEAKKKAE--EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAkkaDEAKKKAEEAK 1457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 560 QGQEI---SDLKQRLQQATRENMEMMDSWKAKLDAlvGDHQRALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLK 636
Cdd:PTZ00121 1458 KAEEAkkkAEEAKKADEAKKKAEEAKKADEAKKKA--EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK 1535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 637 MEHQLELENLKAKHEIDAAVMAKEREDLRsRLQELRDQLEDSEENWKI-----QVETKSNQHTLEIKEVSEKLQKAELRi 711
Cdd:PTZ00121 1536 ADEAKKAEEKKKADELKKAEELKKAEEKK-KAEEAKKAEEDKNMALRKaeeakKAEEARIEEVMKLYEEEKKMKAEEAK- 1613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 712 vdldKSQEEREKVNQLLKEQlmlAEKKMVDYEALQKAEAQSRAEILSLQEKlrvtENRLQAveadhtTQDVNMIENNDNS 791
Cdd:PTZ00121 1614 ----KAEEAKIKAEELKKAE---EEKKKVEQLKKKEAEEKKKAEELKKAEE----ENKIKA------AEEAKKAEEDKKK 1676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 792 DEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQL 871
Cdd:PTZ00121 1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756
|
570
....*....|....*...
gi 1207177222 872 VNISQELLKKERSLNELR 889
Cdd:PTZ00121 1757 KKIAHLKKEEEKKAEEIR 1774
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
526-979 |
9.86e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 62.75 E-value: 9.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 526 RERREESSQLRERYEASlstsQKEIERLKAiterqgqEISDLKQRLQQATREnmemmdswKAKLDALVGDHQRALEELKA 605
Cdd:PRK02224 233 RETRDEADEVLEEHEER----REELETLEA-------EIEDLRETIAETERE--------REELAEEVRDLRERLEELEE 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 606 SLTtDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKA---KHEIDAAVMAKEREDLRSRLQELRDQ---LEDSE 679
Cdd:PRK02224 294 ERD-DLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVaaqAHNEEAESLREDADDLEERAEELREEaaeLESEL 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 680 ENWKIQVETKSNqhtlEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLmlaekkmvdyEALQKAEAQSRAEILSL 759
Cdd:PRK02224 373 EEAREAVEDRRE----EIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER----------DELREREAELEATLRTA 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 760 QEKLRVTENRLQAVEADHTTQDVN---MIENNDNSDEKV--------KLKQNVE------ETLEKLTKREKEVSTLTTQV 822
Cdd:PRK02224 439 RERVEEAEALLEAGKCPECGQPVEgspHVETIEEDRERVeeleaeleDLEEEVEeveerlERAEDLVEAEDRIERLEERR 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 823 DALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELrvlllESPRHSAGV 902
Cdd:PRK02224 519 EDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL-----KERIESLER 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 903 DRDLSREVHRAEwrmkeqklqDDIKTLREKLLLLG------RERLSPDHRRYSMMDPSASDTEVARLRQRLLNTEDALRN 976
Cdd:PRK02224 594 IRTLLAAIADAE---------DEIERLREKREALAelnderRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQ 664
|
...
gi 1207177222 977 ALE 979
Cdd:PRK02224 665 VEE 667
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
332-921 |
1.79e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.08 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 332 ARKISGTTALQEALK-EKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATETEsNLQQVRAMLASTQK 410
Cdd:PTZ00121 1145 ARKAEDAKRVEIARKaEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAE-EERKAEEARKAEDA 1223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 411 DKMELANQLEEEKRKVEDLQfRVEEEsitKGDLEVRGRLQPTPTRLGKSVKQTTVEEKTRVMQLEEELALRKAEvEELQV 490
Cdd:PTZ00121 1224 KKAEAVKKAEEAKKDAEEAK-KAEEE---RNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKA 1298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 491 RFQRGSSGSATDAEDGEPGitsetlvlrEQLLSVGRERREESSQLRERYEASlstsQKEIERLKAITERQGQEISDLKQR 570
Cdd:PTZ00121 1299 EEKKKADEAKKKAEEAKKA---------DEAKKKAEEAKKKADAAKKKAEEA----KKAAEAAKAEAEAAADEAEAAEEK 1365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 571 LQQATRENMEMmdswKAKLDALV--GDHQRALEELKASLTTDCGSGEINGGEGEGslpEMRAALEGLKMEHQLELENLKA 648
Cdd:PTZ00121 1366 AEAAEKKKEEA----KKKADAAKkkAEEKKKADEAKKKAEEDKKKADELKKAAAA---KKKADEAKKKAEEKKKADEAKK 1438
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 649 KHEidaavMAKEREDLRSRLQELR---DQLEDSEENWKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREKVN 725
Cdd:PTZ00121 1439 KAE-----EAKKADEAKKKAEEAKkaeEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKAD 1513
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 726 QLLK-------EQLMLAEKKMvDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIE---------NND 789
Cdd:PTZ00121 1514 EAKKaeeakkaDEAKKAEEAK-KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALrkaeeakkaEEA 1592
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 790 NSDEKVKLKQNVEETLEKLTKREKEVSTLTTQV---DALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHD 866
Cdd:PTZ00121 1593 RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE 1672
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 1207177222 867 ASGQlvniSQELLKKE---RSLNELRVLLLESPRHSAGVDRDLSREVHRAEWRMKEQK 921
Cdd:PTZ00121 1673 DKKK----AEEAKKAEedeKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE 1726
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
378-883 |
2.70e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.94 E-value: 2.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 378 KELAALKARhLQYATETESNLQQVRAMLASTQKDKMELANQLEEEKRKVEDLQFRVEEESITKGDLEVRGRLQPTPTRLg 457
Cdd:COG4717 71 KELKELEEE-LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERL- 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 458 ksvkQTTVEEKTRVMQLEEELALRKAEVEELQvrfqrgssgsatdaedgepgitsetlvlreqllsvgRERREESSQLRE 537
Cdd:COG4717 149 ----EELEERLEELRELEEELEELEAELAELQ------------------------------------EELEELLEQLSL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 538 RYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATREnmemMDSWKAKLdaLVGDHQRALEELK-----ASLTTDCG 612
Cdd:COG4717 189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE----LEQLENEL--EAAALEERLKEARlllliAAALLALL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 613 SGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAavmakEREDLRSRLQELRDQledSEENWKIQVETKSNQ 692
Cdd:COG4717 263 GLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA-----EELQALPALEELEEE---ELEELLAALGLPPDL 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 693 HTLEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRaEILSLQEKLRVTENRLQA 772
Cdd:COG4717 335 SPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAE-EYQELKEELEELEEQLEE 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 773 VEADhttqdvnmIENNDNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLGEktadgLIKEKTR 852
Cdd:COG4717 414 LLGE--------LEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAE-----LLQELEE 480
|
490 500 510
....*....|....*....|....*....|...
gi 1207177222 853 LEAELETMTKK--SHDASGQLVNISQELLKKER 883
Cdd:COG4717 481 LKAELRELAEEwaALKLALELLEEAREEYREER 513
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
526-879 |
3.66e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 3.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 526 RERREESsqlreryEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATR--ENMEMMDSWKAKLDALvgdHQRALEEL 603
Cdd:COG1196 171 KERKEEA-------ERKLEATEENLERLEDILGELERQLEPLERQAEKAERyrELKEELKELEAELLLL---KLRELEAE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 604 KASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAK----HEIDAAVMAKERE-----DLRSRLQELRDQ 674
Cdd:COG1196 241 LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAqaeeYELLAELARLEQDiarleERRRELEERLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 675 LEDSEENWKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRA 754
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 755 EILSLQEKLRVTENRLQAVEADHTTQDVNMIENNdnsDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEE 834
Cdd:COG1196 401 QLEELEEAEEALLERLERLEEELEELEEALAELE---EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1207177222 835 KVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELL 879
Cdd:COG1196 478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
323-974 |
1.24e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.96 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 323 LLTETSSRYARKISGTTALQEALKEK----QQHIEQLLAERDLER--AEVAKATSHIcEVEKELAALKARHLQYATETES 396
Cdd:pfam05483 159 LLKETCARSAEKTKKYEYEREETRQVymdlNNNIEKMILAFEELRvqAENARLEMHF-KLKEDHEKIQHLEEEYKKEIND 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 397 NLQQVRAMLAstqkdkmelanQLEEEKRKVEDLQFRVEEESITKGDLEVRGRLQptptrlgksvkqttveeKTRVMQLEE 476
Cdd:pfam05483 238 KEKQVSLLLI-----------QITEKENKMKDLTFLLEESRDKANQLEEKTKLQ-----------------DENLKELIE 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 477 ELALRKAEVEELQVRFQRGSSGSATDAEDGEpgITSETLVlreQLLSVGRERREESSQLRERYEASLSTSQKEIERLKAI 556
Cdd:pfam05483 290 KKDHLTKELEDIKMSLQRSMSTQKALEEDLQ--IATKTIC---QLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEL 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 557 TERQGQEISDLKQRLQQATREnMEMMDSWKAKLDALVGDHQRALEELKASLTTD--CGSGEINGGEGEGSLPEMRAALEG 634
Cdd:pfam05483 365 LRTEQQRLEKNEDQLKIITME-LQKKSSELEEMTKFKNNKEVELEELKKILAEDekLLDEKKQFEKIAEELKGKEQELIF 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 635 LKMEHQLELENLkakhEIDAAVMAKEREDLRSRLQELRDQLEDsEENWKIQVETKSNQHTLEIKEVSeklQKAELRIVDL 714
Cdd:pfam05483 444 LLQAREKEIHDL----EIQLTAIKTSEEHYLKEVEDLKTELEK-EKLKNIELTAHCDKLLLENKELT---QEASDMTLEL 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 715 DKSQEErekVNQLLKEQlmlaEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAvEADHTTQDVNMIENNDNSDEK 794
Cdd:pfam05483 516 KKHQED---IINCKKQE----ERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKC-KLDKSEENARSIEYEVLKKEK 587
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 795 -VKLKQNVEETLEK-LTKREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTkKSHDASGQLV 872
Cdd:pfam05483 588 qMKILENKCNNLKKqIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEII-DNYQKEIEDK 666
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 873 NISQELLKKErsLNELRVLLLESPRHSAGVDRDLSREVHRAEWRMKEQKLQDDiKTLREKLLLLGrerLSPDHRRYSMMD 952
Cdd:pfam05483 667 KISEEKLLEE--VEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYD-KIIEERDSELG---LYKNKEQEQSSA 740
|
650 660
....*....|....*....|..
gi 1207177222 953 PSASDTEVARLRQRLLNTEDAL 974
Cdd:pfam05483 741 KAALEIELSNIKAELLSLKKQL 762
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
343-944 |
3.26e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 58.06 E-value: 3.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 343 EALKEKQQHIEQLlAERDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAM---LASTQKDKMELANQL 419
Cdd:pfam02463 339 ELEKELKELEIKR-EAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELkseEEKEAQLLLELARQL 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 420 EEEKRKVEDLQFRVEEESITKGDLEVR----GRLQPTPTRLGKSVKQTTVEEKTRVMQLEEELALRKAEVEELQVRFQRG 495
Cdd:pfam02463 418 EDLLKEEKKEELEILEEEEESIELKQGklteEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 496 SSGSATDAEDGEPGITSETLVLREQLLSVGRERREESSQLRERYEASLSTS-QKEIERLKAITERQGQEISDLKQRLQQA 574
Cdd:pfam02463 498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAvIVEVSATADEVEERQKLVRALTELPLGA 577
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 575 TRENMEMMDSWKAKLDALVGDHQRALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDA 654
Cdd:pfam02463 578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEG 657
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 655 AVMAKEREDLRSRLQELRDQLEDSEENWKIQVETKSNQHTLEIKEVSEKLQKAELRivdlDKSQEEREKVNQLLKEQLML 734
Cdd:pfam02463 658 LAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELK----KLKLEAEELLADRVQEAQDK 733
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 735 AEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNmIENNDNSDEKVKLKQNVEETLEKLTKREKE 814
Cdd:pfam02463 734 INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK-TEKLKVEEEKEEKLKAQEEELRALEEELKE 812
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 815 VSTLTTQVDALKTQITALEEKVRLGEKTadgLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLLLE 894
Cdd:pfam02463 813 EAELLEEEQLLIEQEEKIKEEELEELAL---ELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 1207177222 895 SPRHSAGVDRDLSREVHRAEWRMKEQKLQDDIKTLREKLLLLGRERLSPD 944
Cdd:pfam02463 890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEE 939
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
659-863 |
7.76e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 56.57 E-value: 7.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 659 KEREDLRSRLQELRDQLEdsEENWKIQVETKSNQhtleikEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEK- 737
Cdd:TIGR04523 349 KELTNSESENSEKQRELE--EKQNEIEKLKKENQ------SYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQe 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 738 ---KMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMienNDNSDEKVKLKQNVEETLEKLTKREKE 814
Cdd:TIGR04523 421 kelLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL---KVLSRSINKIKQNLEQKQKELKSKEKE 497
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1207177222 815 VSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKK 863
Cdd:TIGR04523 498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE 546
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
651-996 |
1.29e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.71 E-value: 1.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 651 EIDAAVMAKEREDLRSRLQELRDQLEdseenwkiQVETKSNQHTLEIKEVSEKLQKAELRIvdldksQEEREKVNQLLKE 730
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELE--------ELEAELEELEAELAELEAELEELRLEL------EELELELEEAQAE 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 731 qlmlaekkmvdYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDvnmienndnsDEKVKLKQNVEETLEKLTK 810
Cdd:COG1196 290 -----------EYELLAELARLEQDIARLEERRRELEERLEELEEELAELE----------EELEELEEELEELEEELEE 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 811 REKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRV 890
Cdd:COG1196 349 AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 891 LLLESprhsagVDRDLSREVHRAEWRMKEQKLQDDIKTLREKLLLLGRERLSPDhrrysmmdpsASDTEVARLRQRLLNT 970
Cdd:COG1196 429 ALAEL------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE----------AALAELLEELAEAAAR 492
|
330 340
....*....|....*....|....*.
gi 1207177222 971 EDALRNALEHNQHVDQLVQAMRTRPD 996
Cdd:COG1196 493 LLLLLEAEADYEGFLEGVKAALLLAG 518
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
324-774 |
1.67e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.46 E-value: 1.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 324 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQY--ATETESNLQQV 401
Cdd:PRK03918 298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYeeAKAKKEELERL 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 402 RAMLASTQKDKMElaNQLEEEKRKVEDLQFRVEEESITKGDLEVRGRLQPTPTRLGKSVKQT--------TVEEKTRVMQ 473
Cdd:PRK03918 378 KKRLTGLTPEKLE--KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLE 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 474 --------LEEELALRKAEVEELQVRFQRgssgsatdaedgepgitSETLVLREQLLSVGRERREESSQLRERYEA---- 541
Cdd:PRK03918 456 eytaelkrIEKELKEIEEKERKLRKELRE-----------------LEKVLKKESELIKLKELAEQLKELEEKLKKynle 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 542 SLSTSQKEIERLKAITERQGQEISDLKQRLqqatrENMEMMDSWKAKLDALVGDHQRALEELKASLTTDCGSGEINGGEG 621
Cdd:PRK03918 519 ELEKKAEEYEKLKEKLIKLKGEIKSLKKEL-----EKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEER 593
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 622 EGSL-PEMRAALEGLKMEHQLELENLKAKHEIDAAVMA-KEREDLRSRLQELRDQLEDSEENW-KIQVETKSNQHTleik 698
Cdd:PRK03918 594 LKELePFYNEYLELKDAEKELEREEKELKKLEEELDKAfEELAETEKRLEELRKELEELEKKYsEEEYEELREEYL---- 669
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 699 EVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEKKMVDYEALQKAeaqsRAEILSLQEKLR-----VTENRLQAV 773
Cdd:PRK03918 670 ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKA----LERVEELREKVKkykalLKERALSKV 745
|
.
gi 1207177222 774 E 774
Cdd:PRK03918 746 G 746
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
536-837 |
2.28e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.07 E-value: 2.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 536 RERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATRENMEMMDSWKAKLdalvgdhQRALEELKASLTTdCGSGE 615
Cdd:TIGR02169 239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-------KEKIGELEAEIAS-LERSI 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 616 INGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEidaaVMAKEREDLRSRLQELRDQLEDSEEnwKIQVETKSNQHTL 695
Cdd:TIGR02169 311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIE----EERKRRDKLTEEYAELKEELEDLRA--ELEEVDKEFAETR 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 696 EikEVSEKLQKaelrivdLDKSQEERekvNQLLKEQLMLAEKKmvdyEALQKAEAQSRAEILSLQEKLRVTENRLQAVEA 775
Cdd:TIGR02169 385 D--ELKDYREK-------LEKLKREI---NELKRELDRLQEEL----QRLSEELADLNAAIAGIEAKINELEEEKEDKAL 448
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1207177222 776 DHTTQDVNMIEnndNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVR 837
Cdd:TIGR02169 449 EIKKQEWKLEQ---LAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVR 507
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
395-930 |
2.53e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 55.12 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 395 ESNLQQVRAMLASTQKDKMELAnqLEEEKRKVEDLQFRVEEESitkgDLEVRGRLQptptrlgksVKQTTVEEKTRVMQL 474
Cdd:pfam15921 58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN----ELHEKQKFY---------LRQSVIDLQTKLQEM 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 475 EEElalRKAEVEelqvrFQRGSSGSATDaedgepgitsetlvLREQLLSVGRERrEESSQLRERYeasLSTSQKEIERL- 553
Cdd:pfam15921 123 QME---RDAMAD-----IRRRESQSQED--------------LRNQLQNTVHEL-EAAKCLKEDM---LEDSNTQIEQLr 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 554 KAITERQG--QEISDLKQRLQQATRENMEMMDSWKA-KLDALVGDHQRALEELKASLTTDCGSGEINGGEGEGSLPEMRA 630
Cdd:pfam15921 177 KMMLSHEGvlQEIRSILVDFEEASGKKIYEHDSMSTmHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQN 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 631 ALEGLKMEHQLELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLEdseenwkIQVETKSNQHTLEIKEVSEKLQKAELR 710
Cdd:pfam15921 257 KIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLE-------IIQEQARNQNSMYMRQLSDLESTVSQL 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 711 IVDLDKSQEEREKVNQLLKEQLMLAEKKMvdyealqkaeAQSRAEILSLQEKLRVTENRLQAVEAD-HTTQDVNMIENND 789
Cdd:pfam15921 330 RSELREAKRMYEDKIEELEKQLVLANSEL----------TEARTERDQFSQESGNLDDQLQKLLADlHKREKELSLEKEQ 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 790 NS---DEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHD 866
Cdd:pfam15921 400 NKrlwDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRK 479
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1207177222 867 ASGQLVNISQELLKKERSLNELRVLLLESPRHSAGVDRDLSREVHRAEWRMKE-QKLQDDIKTLR 930
Cdd:pfam15921 480 VVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQElQHLKNEGDHLR 544
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
343-807 |
2.73e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 2.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 343 EALKEKQQHIEQLLAERdlERAEVAKATSHicEVEK-ELAALKARHLQYATETESNLQQVR----AMLASTQKDKMELAN 417
Cdd:PTZ00121 1401 EEDKKKADELKKAAAAK--KKADEAKKKAE--EKKKaDEAKKKAEEAKKADEAKKKAEEAKkaeeAKKKAEEAKKADEAK 1476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 418 QLEEEKRKVEDLQFRVEEESITKGDLEVRGRLQPTPTRLGKSVKQTTVEEKTRVMQLEEELALRKAE----VEELQvrfq 493
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEekkkADELK---- 1552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 494 rgssgSATDAEDGEPGITSETLVLREQLLSVGRERREESSQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQ 573
Cdd:PTZ00121 1553 -----KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 574 ATRENMEMMDSWKAKldalvGDHQRALEELKASLTTDCGSGEINGGEGEGslpEMRAALEGLKMEhqlELENLKAKHEID 653
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKE-----AEEKKKAEELKKAEEENKIKAAEEAKKAEE---DKKKAEEAKKAE---EDEKKAAEALKK 1696
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 654 AAVMAKEREDLRSRLQELR---DQLEDSEENWKIQVETksnqhtLEIKEVSEKLQKAELRivdldKSQEEREKVNQLLKE 730
Cdd:PTZ00121 1697 EAEEAKKAEELKKKEAEEKkkaEELKKAEEENKIKAEE------AKKEAEEDKKKAEEAK-----KDEEEKKKIAHLKKE 1765
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 731 QLMLAEKKMVDYEALQKAEAQSraeilslqeklrvtENRLQAVEADHTTQDV-----NMIENNDNSDEKVKLKQNVEETL 805
Cdd:PTZ00121 1766 EEKKAEEIRKEKEAVIEEELDE--------------EDEKRRMEVDKKIKDIfdnfaNIIEGGKEGNLVINDSKEMEDSA 1831
|
..
gi 1207177222 806 EK 807
Cdd:PTZ00121 1832 IK 1833
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
340-813 |
5.44e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.91 E-value: 5.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 340 ALQEALKEKQQHIEQLLAE-RDLEraEVAKATSHICEVEKELAALKARHLQYATE------TESNLQQVRAMLASTQKDK 412
Cdd:PRK03918 256 KLEEKIRELEERIEELKKEiEELE--EKVKELKELKEKAEEYIKLSEFYEEYLDElreiekRLSRLEEEINGIEERIKEL 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 413 MELANQLEEEKRKVEDLQFRVEEesiTKGDLEVRGRLQPTPTRLGKSVKQTTVEEKTRVMQLEEELALRKAEVEELQVRF 492
Cdd:PRK03918 334 EEKEERLEELKKKLKELEKRLEE---LEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKI 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 493 QRGSSGSATDAEDGEPGItSETLVLREQLLSVGRERREE-SSQLRERYEASLSTSQKEIERLKAiterqgqEISDLKQRL 571
Cdd:PRK03918 411 TARIGELKKEIKELKKAI-EELKKAKGKCPVCGRELTEEhRKELLEEYTAELKRIEKELKEIEE-------KERKLRKEL 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 572 qqatrENMEMMDSWKAKLDAL--VGDHQRALEE-LKASLTTDCGSGEINGGEGEGSLPEMRAALEGLK--MEHQLELENL 646
Cdd:PRK03918 483 -----RELEKVLKKESELIKLkeLAEQLKELEEkLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKkeLEKLEELKKK 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 647 KAKHEIDAAVMAKEREDLRSRL--------QELRDQLEDSEENWKIQVETKSNQHTLEIKEvsEKLQKAELRIVDLDKSQ 718
Cdd:PRK03918 558 LAELEKKLDELEEELAELLKELeelgfesvEELEERLKELEPFYNEYLELKDAEKELEREE--KELKKLEEELDKAFEEL 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 719 EEREKVNQLLKEQLMLAEKKMVD--YEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTtqdvNMIENNDNSDEKVK 796
Cdd:PRK03918 636 AETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLE----KLKEELEEREKAKK 711
|
490
....*....|....*...
gi 1207177222 797 LKQNVEETLEKLTK-REK 813
Cdd:PRK03918 712 ELEKLEKALERVEElREK 729
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
654-892 |
6.40e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 6.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 654 AAVMAKEREDLRSRLQELRDQLEdseenwkiQVETKSNQHTLEIKEVSEKLQKAELRIVDLdksqeerEKVNQLLKEQLM 733
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIA--------ELEKELAALKKEEKALLKQLAALERRIAAL-------ARRIRALEQELA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 734 LAEKKMvdyEALQKAEAQSRAEILSLQEKLRvteNRLQAVEADHTTQDVNMIENNDNSDEKVKLKQNVEETLEkltKREK 813
Cdd:COG4942 80 ALEAEL---AELEKEIAELRAELEAQKEELA---ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP---ARRE 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207177222 814 EVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLL 892
Cdd:COG4942 151 QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
526-858 |
6.66e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 6.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 526 RERREESsqlreryEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATR--------ENMEMmDSWKAKLDALVgDHQ 597
Cdd:TIGR02168 171 KERRKET-------ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykelkaelRELEL-ALLVLRLEELR-EEL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 598 RALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQ------LELENLKAKHEIDAAVMAKEREDLRSRLQEL 671
Cdd:TIGR02168 242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEelqkelYALANEISRLEQQKQILRERLANLERQLEEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 672 RDQLEDSEENwKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLmlaekkmvdyEALQKAEAQ 751
Cdd:TIGR02168 322 EAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----------ETLRSKVAQ 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 752 SRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENNDNSDE--KVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQI 829
Cdd:TIGR02168 391 LELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaeLKELQAELEELEEELEELQEELERLEEALEELREEL 470
|
330 340
....*....|....*....|....*....
gi 1207177222 830 TALEEKVRLGEKTADGLIKEKTRLEAELE 858
Cdd:TIGR02168 471 EEAEQALDAAERELAQLQARLDSLERLQE 499
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
625-1000 |
7.12e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.57 E-value: 7.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 625 LPEMRAALEGLKMEHQLELENlKAKHEIDAAVMAKERE----DLRSRLQELRDQLEDSEENWKIQVETksnqhtleIKEV 700
Cdd:pfam05483 217 LKEDHEKIQHLEEEYKKEIND-KEKQVSLLLIQITEKEnkmkDLTFLLEESRDKANQLEEKTKLQDEN--------LKEL 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 701 SEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLA--------EKKMVDYEALQKAEA-------QSRAEILSLQEKLRV 765
Cdd:pfam05483 288 IEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIAtkticqltEEKEAQMEELNKAKAahsfvvtEFEATTCSLEELLRT 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 766 TENRLQAVEADHTTQDVNMIENNDNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQvdalKTQITALEEKVRLGEKTADG 845
Cdd:pfam05483 368 EQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDE----KKQFEKIAEELKGKEQELIF 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 846 LI----KEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNEL----RVLLLESPRHSAGVDrDLSREV------- 910
Cdd:pfam05483 444 LLqareKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELtahcDKLLLENKELTQEAS-DMTLELkkhqedi 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 911 ---HRAEWRM---------KEQKLQDDIKTLREKLLLLGRE-RLSPDHRRYSMMDPSASDTEVARLRQRLLNTEDALRNA 977
Cdd:pfam05483 523 incKKQEERMlkqienleeKEMNLRDELESVREEFIQKGDEvKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQ 602
|
410 420
....*....|....*....|....
gi 1207177222 978 LEH-NQHVDQLVQAMRTRPDKNQA 1000
Cdd:pfam05483 603 IENkNKNIEELHQENKALKKKGSA 626
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
339-608 |
1.43e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 339 TALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYA---TETESNLQQVRAMLASTQKDKMEL 415
Cdd:TIGR02168 694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEeriAQLSKELTELEAEIEELEERLEEA 773
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 416 ANQLEEEKRKVEDLQFRVEE-----ESITKGDLEVRGRLQPTPTRLG------KSVKQTTVEEKTRVMQLEEELALRKAE 484
Cdd:TIGR02168 774 EEELAEAEAEIEELEAQIEQlkeelKALREALDELRAELTLLNEEAAnlrerlESLERRIAATERRLEDLEEQIEELSED 853
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 485 VEELqvrfqrgsSGSATDAEDGEPGITSETLVLREQLLSVGRERREESSQLRERyEASLSTSQKEIERLKAITERQGQEI 564
Cdd:TIGR02168 854 IESL--------AAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKL 924
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1207177222 565 SDLKQRLQQATRE--------------NMEMMDSWKAKLDALVGDHQRALEELKASLT 608
Cdd:TIGR02168 925 AQLELRLEGLEVRidnlqerlseeyslTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
391-932 |
1.47e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 391 ATETESNLQQVRAMLASTQKDKMELANQLEEEKRKVEDLQfRVEE----ESITKGDLEVRGRLQPTPTRLGKSVKQTTVE 466
Cdd:PTZ00121 1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDAR-KAEEarkaEDARKAEEARKAEDAKRVEIARKAEDARKAE 1167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 467 EKTRVMQLEEELALRKAEveelQVRfqrgssgSATDAEDGEPGITSETLVLREQLLSVGRERREESSQLRERYEASLSTS 546
Cdd:PTZ00121 1168 EARKAEDAKKAEAARKAE----EVR-------KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAK 1236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 547 QKEIERLKAITERQGQEISDLKQ-RLQQATRENMEMMDSWKAKLDAL-VGDHQRALEELKASLTTDCGSGEINGGEGEGS 624
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEaRMAHFARRQAAIKAEEARKADELkKAEEKKKADEAKKAEEKKKADEAKKKAEEAKK 1316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 625 LPEMRAALEGLKM---EHQLELENLKAKHEIDAAVMAKEREDLR-SRLQELRDQLEDSEENWKIQVETKSNQHTLEIKEV 700
Cdd:PTZ00121 1317 ADEAKKKAEEAKKkadAAKKKAEEAKKAAEAAKAEAEAAADEAEaAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 701 SEKLQKAELRIVDLDKSQEEREKVNQLLK---------EQLMLAEKKMVDYEALQKAEAQSRAEILS--LQEKLRVTENR 769
Cdd:PTZ00121 1397 KKKAEEDKKKADELKKAAAAKKKADEAKKkaeekkkadEAKKKAEEAKKADEAKKKAEEAKKAEEAKkkAEEAKKADEAK 1476
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 770 LQAVEADHTTQDVNMIENNDNSDEKVKLKQNVEETLEKLTKRE--KEVSTLTTQVDALKTQITALEEKVRLGE--KTADG 845
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEeaKKADEAKKAEEAKKADEAKKAEEKKKADelKKAEE 1556
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 846 LIKEKTRLEAEletMTKKSHDASGQLVNISQELLKKERS-LNELRVLLLESPRHSAGVDRDLSREVHRAEWRMKEQKLQD 924
Cdd:PTZ00121 1557 LKKAEEKKKAE---EAKKAEEDKNMALRKAEEAKKAEEArIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633
|
....*...
gi 1207177222 925 DIKTLREK 932
Cdd:PTZ00121 1634 KVEQLKKK 1641
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
517-967 |
2.06e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 51.67 E-value: 2.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 517 LREQLLSVGRERREESSQLRERYEASLSTSQKEIERLKAITERqgqeISDLKQRL---QQATRENMEMMDSWKAKLDALV 593
Cdd:pfam05557 14 LQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKR----IRLLEKREaeaEEALREQAELNRLKKKYLEALN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 594 G------DHQRALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENlkakheidaavmAKEREDLRSR 667
Cdd:pfam05557 90 KklnekeSQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAK------------ASEAEQLRQN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 668 LQELRDQLEDSEEnwKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQ----EEREKVNQLLKEQLMLAEKKMvDYE 743
Cdd:pfam05557 158 LEKQQSSLAEAEQ--RIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELerlrEHNKHLNENIENKLLLKEEVE-DLK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 744 ALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENNDNSDEKVKLKQnveetlEKLTKREkEVSTLTTQVD 823
Cdd:pfam05557 235 RKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQ------REIVLKE-ENSSLTSSAR 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 824 ALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASgQLVNISQELLK---KERSLNELRVLLLESPRHSA 900
Cdd:pfam05557 308 QLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLT-KERDGYRAILEsydKELTMSNYSPQLLERIEEAE 386
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207177222 901 GVDRDLsrEVHRAEWRMKEQKLQDDIKTLREKLLLLGRErLSPDHRRYSMMDPSASDTEVARLRQRL 967
Cdd:pfam05557 387 DMTQKM--QAHNEEMEAQLSVAEEELGGYKQQAQTLERE-LQALRQQESLADPSYSKEEVDSLRRKL 450
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
667-979 |
2.56e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.60 E-value: 2.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 667 RLQELRDQLEDSEENWKIQVETKSNQHTLeIKEVSEKLQKAELRIVDLDKSQEE-REKVNQLLKEQLMLAEKKmVDYEAL 745
Cdd:PRK03918 166 NLGEVIKEIKRRIERLEKFIKRTENIEEL-IKEKEKELEEVLREINEISSELPElREELEKLEKEVKELEELK-EEIEEL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 746 QKAEAQSRAEILSLQEKLRVTENRLQAVEA-----DHTTQDVNMIEnnDNSDEKVKLKQNVEETLEKLTKREKEVSTLTT 820
Cdd:PRK03918 244 EKELESLEGSKRKLEEKIRELEERIEELKKeieelEEKVKELKELK--EKAEEYIKLSEFYEEYLDELREIEKRLSRLEE 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 821 QVDALKTQITALEEKVRLGEKTaDGLIKEKTRLEAELETMTKKSHDASGQLVNISQ-ELLKKERSLNELRVLLLESPRHS 899
Cdd:PRK03918 322 EINGIEERIKELEEKEERLEEL-KKKLKELEKRLEELEERHELYEEAKAKKEELERlKKRLTGLTPEKLEKELEELEKAK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 900 AGVDRDLSR-EVHRAEWRMKEQKLQDDIKTLRE---KLLLLGRErLSPDHRRYSMMDPSAsdtEVARLRQRLLNTEDALR 975
Cdd:PRK03918 401 EEIEEEISKiTARIGELKKEIKELKKAIEELKKakgKCPVCGRE-LTEEHRKELLEEYTA---ELKRIEKELKEIEEKER 476
|
....
gi 1207177222 976 NALE 979
Cdd:PRK03918 477 KLRK 480
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
520-837 |
3.84e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.22 E-value: 3.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 520 QLLSVGRERREESSQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQatrenmemMDSWKAKLDALVGDHQRA 599
Cdd:TIGR02169 709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE--------LEARIEELEEDLHKLEEA 780
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 600 LEELKASLttdcgsgeinggeGEGSLPEMRAALEGLKMEHQ------LELENLKAKHEIDAAVMAKEREDLRSRLQELRD 673
Cdd:TIGR02169 781 LNDLEARL-------------SHSRIPEIQAELSKLEEEVSriearlREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE 847
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 674 Q---LEDSEENWKIQVETKSNQ--------HTL---------EIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLM 733
Cdd:TIGR02169 848 QiksIEKEIENLNGKKEELEEEleeleaalRDLesrlgdlkkERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 734 LAEKKMVDYEALQKAEAQSRAEILSL---QEKLRVTENRLQAVEadhttqDVNMienndnsdekvKLKQNVEETLEKLTK 810
Cdd:TIGR02169 928 ALEEELSEIEDPKGEDEEIPEEELSLedvQAELQRVEEEIRALE------PVNM-----------LAIQEYEEVLKRLDE 990
|
330 340
....*....|....*....|....*..
gi 1207177222 811 REKEVSTLTTQVDALKTQITALEEKVR 837
Cdd:TIGR02169 991 LKEKRAKLEEERKAILERIEEYEKKKR 1017
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
339-777 |
4.40e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 50.81 E-value: 4.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 339 TALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHlqyaTETESNLQQVR---------------- 402
Cdd:PRK02224 275 EELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRD----EELRDRLEECRvaaqahneeaeslred 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 403 -AMLASTQKDKMELANQLEEE----KRKVEDLQFRVEE--ESITkgdlEVRGRLQPTPTRLGK--SVKQTTVEEKTRVMQ 473
Cdd:PRK02224 351 aDDLEERAEELREEAAELESEleeaREAVEDRREEIEEleEEIE----ELRERFGDAPVDLGNaeDFLEELREERDELRE 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 474 LEEEL--ALRKAE--VEELQVRFQRGSSGSATDAEDGEPGITSetlvlreqlLSVGRERREESSQLRERYEASLSTSQKE 549
Cdd:PRK02224 427 REAELeaTLRTARerVEEAEALLEAGKCPECGQPVEGSPHVET---------IEEDRERVEELEAELEDLEEEVEEVEER 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 550 IERLKAITErQGQEISDLKQRLQQATRENMEMMDSWKAKLDALVGDHQRAlEELKASLTTDCGSGEINGGEGEGSLPEMr 629
Cdd:PRK02224 498 LERAEDLVE-AEDRIERLEERREDLEELIAERRETIEEKRERAEELRERA-AELEAEAEEKREAAAEAEEEAEEAREEV- 574
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 630 AALEGLKMEHQLELENLKAKHEIDAAVMAKEREdlRSRLQELRDQLEDSEENWKIQVETKSNQH-TLE-------IKEVS 701
Cdd:PRK02224 575 AELNSKLAELKERIESLERIRTLLAAIADAEDE--IERLREKREALAELNDERRERLAEKRERKrELEaefdearIEEAR 652
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207177222 702 EKLQKAELRIVDLD-KSQEEREKVNQLLKEQLMLAEkkmvdyealqkaeaqSRAEILSLQEKLRVTENRLQAVEADH 777
Cdd:PRK02224 653 EDKERAEEYLEQVEeKLDELREERDDLQAEIGAVEN---------------ELEELEELRERREALENRVEALEALY 714
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
519-971 |
6.14e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.45 E-value: 6.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 519 EQLLSVGRERREESSQLRErYEASLSTSQKEIERLKAITErqgqEISDLKQRLQQATREnmemmdswKAKLDALVGDHQR 598
Cdd:PRK03918 200 KELEEVLREINEISSELPE-LREELEKLEKEVKELEELKE----EIEELEKELESLEGS--------KRKLEEKIRELEE 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 599 ALEELKASLttdcgsgeinggegeGSLPEMRAALEGLK--MEHQLELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLE 676
Cdd:PRK03918 267 RIEELKKEI---------------EELEEKVKELKELKekAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 677 DSEENWKiqvetksnqhtlEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLA--------EKKMVDYEALQKA 748
Cdd:PRK03918 332 ELEEKEE------------RLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKkrltgltpEKLEKELEELEKA 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 749 EAQSRAEILSLQEKLRVTENRL----QAVEADHTTQDV--------------NMIENNDNSDEKV-KLKQNVEETLEKLT 809
Cdd:PRK03918 400 KEEIEEEISKITARIGELKKEIkelkKAIEELKKAKGKcpvcgrelteehrkELLEEYTAELKRIeKELKEIEEKERKLR 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 810 KREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELR 889
Cdd:PRK03918 480 KELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 890 VLLLESprhsagvdRDLSREVHRAEWRMKEQKLQdDIKTLREKLlllgrERLSPDHRRYSMMDPSASDTEVARLRQRLLN 969
Cdd:PRK03918 560 ELEKKL--------DELEEELAELLKELEELGFE-SVEELEERL-----KELEPFYNEYLELKDAEKELEREEKELKKLE 625
|
..
gi 1207177222 970 TE 971
Cdd:PRK03918 626 EE 627
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
340-890 |
6.49e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.22 E-value: 6.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 340 ALQEALKEKQQHIEQLLAE----RDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQKDKMEL 415
Cdd:pfam12128 280 ERQETSAELNQLLRTLDDQwkekRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENL 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 416 ANQLEEEKRKVEDLQfRVEEESITKGDLEVRGRLQPTPTRLGKS----VKQTTVEE---KTRVMQLEEELALRKAEVEEL 488
Cdd:pfam12128 360 EERLKALTGKHQDVT-AKYNRRRSKIKEQNNRDIAGIKDKLAKIrearDRQLAVAEddlQALESELREQLEAGKLEFNEE 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 489 QVRFQrgSSGSATDAEDGEPGITSETLVLREQLLSVGRERREESSQLReryeASLSTSQKEIERLKAITERQGQEISDLK 568
Cdd:pfam12128 439 EYRLK--SRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAAN----AEVERLQSELRQARKRRDQASEALRQAS 512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 569 QRLQQ---ATRENMEMMDS---------------WKAKLDALVGDHQRALEELKASLTTDCGSGEINGGEGEGSLPEMRA 630
Cdd:pfam12128 513 RRLEErqsALDELELQLFPqagtllhflrkeapdWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDV 592
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 631 AlEGLKMEHQLELENLKAKHEIDAAVMAKERED-----LRSRLQELRDQLEDSEENWK--------IQVETKSNQHTLEi 697
Cdd:pfam12128 593 P-EWAASEEELRERLDKAEEALQSAREKQAAAEeqlvqANGELEKASREETFARTALKnarldlrrLFDEKQSEKDKKN- 670
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 698 KEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQL--MLAEKKMVDYEALQKAEAQSRAEILSL-QEKLRVTENRLQAVE 774
Cdd:pfam12128 671 KALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQkeQKREARTEKQAYWQVVEGALDAQLALLkAAIAARRSGAKAELK 750
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 775 ADHTTQDVNMIENNDNSDEKVKLKQ---NVEETLEKLTKREKEV--------STLTTQVDALKTQITALEEKVRLGEKTA 843
Cdd:pfam12128 751 ALETWYKRDLASLGVDPDVIAKLKReirTLERKIERIAVRRQEVlryfdwyqETWLQRRPRLATQLSNIERAISELQQQL 830
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 1207177222 844 DGLIKEKTRLEAELETMTKKSHDasgQLVNISQELLKKE---RSLNELRV 890
Cdd:pfam12128 831 ARLIADTKLRRAKLEMERKASEK---QQVRLSENLRGLRcemSKLATLKE 877
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
341-894 |
7.60e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.17 E-value: 7.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 341 LQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARhlqyATETESNLQQVRAMLastqKDKMELANQLE 420
Cdd:pfam01576 24 AESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAAR----KQELEEILHELESRL----EEEEERSQQLQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 421 EEKRK----VEDLQFRVEEESITkgdlevRGRLQptptrlgksVKQTTVEEKtrVMQLEEELALrkaeVEELQVRFQRgs 496
Cdd:pfam01576 96 NEKKKmqqhIQDLEEQLDEEEAA------RQKLQ---------LEKVTTEAK--IKKLEEDILL----LEDQNSKLSK-- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 497 sgsatdaedgEPGITSETLVLREQLLSVGRERREESSQLRERYEASLSTSQkeiERLKAiTERQGQEISDLKQRLQQATR 576
Cdd:pfam01576 153 ----------ERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLE---ERLKK-EEKGRQELEKAKRKLEGEST 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 577 ENMEMMDSWKAKLDALVGDHQRALEELKASLT---------TDCGSGEINGGEGEGSLPE-------MRAALEGLKMEHQ 640
Cdd:pfam01576 219 DLQEQIAELQAQIAELRAQLAKKEEELQAALArleeetaqkNNALKKIRELEAQISELQEdleseraARNKAEKQRRDLG 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 641 LELENLKAKHEIDAAVMAKEREdLRSR----LQELRDQLEDSEENWKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLDK 716
Cdd:pfam01576 299 EELEALKTELEDTLDTTAAQQE-LRSKreqeVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEK 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 717 SQEEREKVNQLLKEQL-MLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAV-----EADHTTQDVNMIE--NN 788
Cdd:pfam01576 378 AKQALESENAELQAELrTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLsklqsELESVSSLLNEAEgkNI 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 789 DNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDAS 868
Cdd:pfam01576 458 KLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDA 537
|
570 580
....*....|....*....|....*.
gi 1207177222 869 GQLVNISQELLKKERSLNELRVLLLE 894
Cdd:pfam01576 538 GTLEALEEGKKRLQRELEALTQQLEE 563
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
341-888 |
1.85e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.86 E-value: 1.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 341 LQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATE---TESNLQQVRAML-----------A 406
Cdd:TIGR04523 129 LEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEklnIQKNIDKIKNKLlklelllsnlkK 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 407 STQKDKmELANQLEEEKRKVEDLQFRVEEESITKGDLEVRgrLQPTPTRLgKSVKQTTVEEKTRVMQLEEELALRKAEVE 486
Cdd:TIGR04523 209 KIQKNK-SLESQISELKKQNNQLKDNIEKKQQEINEKTTE--ISNTQTQL-NQLKDEQNKIKKQLSEKQKELEQNNKKIK 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 487 ELQVRFQRGSSGSATDAEDGEPGITSEtlvLREQLLSVGRERREESSQLREryeaslstSQKEIERLKaiterqgQEISD 566
Cdd:TIGR04523 285 ELEKQLNQLKSEISDLNNQKEQDWNKE---LKSELKNQEKKLEEIQNQISQ--------NNKIISQLN-------EQISQ 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 567 LKQRLQQATRENMEMMDSWKAKLDA---LVGDHQRALEELKaSLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQL-- 641
Cdd:TIGR04523 347 LKKELTNSESENSEKQRELEEKQNEiekLKKENQSYKQEIK-NLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELle 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 642 -ELENLKAKHeIDAAVMAKEREDLRSRLQELRDQLEDSEENWKIQVET-----KSNQHTLEIKEVSEKLQKAELRIVDLD 715
Cdd:TIGR04523 426 kEIERLKETI-IKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVlsrsiNKIKQNLEQKQKELKSKEKELKKLNEE 504
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 716 KSQEErEKVNQLLKEQLMLAEKKmvdyEALQKAEAQSRAEILSLQEKLRVTENRLqaveadhtTQDVNMIENNDNSDEKV 795
Cdd:TIGR04523 505 KKELE-EKVKDLTKKISSLKEKI----EKLESEKKEKESKISDLEDELNKDDFEL--------KKENLEKEIDEKNKEIE 571
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 796 KLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNIS 875
Cdd:TIGR04523 572 ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIK 651
|
570
....*....|...
gi 1207177222 876 QELLKKERSLNEL 888
Cdd:TIGR04523 652 ETIKEIRNKWPEI 664
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
340-708 |
2.02e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.81 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 340 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQKdkmelanQL 419
Cdd:TIGR00618 532 RGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEK-------LS 604
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 420 EEEKRKVEDLQFRVEEESITKGDLEVRGRLQPTPTRLGKsvkqttveEKTRVMQLEEELALRKAEVEELQVRFQRGSSGS 499
Cdd:TIGR00618 605 EAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELAL--------KLTALHALQLTLTQERVREHALSIRVLPKELLA 676
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 500 ATDAEDGEpgitsetLVLREQLLSVGRERREESSQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATRENM 579
Cdd:TIGR00618 677 SRQLALQK-------MQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 580 EMMDSwkaKLDALVGDHQRALEELKASLTTDCGSG--EINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVM 657
Cdd:TIGR00618 750 HQART---VLKARTEAHFNNNEEVTAALQTGAELShlAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETL 826
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1207177222 658 AKEREDLRSRLQ-------ELRDQLEDSEENWKIQvetksNQHTLEIKEVSEKLQKAE 708
Cdd:TIGR00618 827 VQEEEQFLSRLEeksatlgEITHQLLKYEECSKQL-----AQLTQEQAKIIQLSDKLN 879
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
340-860 |
2.79e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 48.11 E-value: 2.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 340 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALkarhlqyaTETESNLQQVRAMLASTQKDKMELANQL 419
Cdd:PRK02224 210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--------ETLEAEIEDLRETIAETEREREELAEEV 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 420 EEEKRKVEDLQfrvEEESITKGDLEVRGrlqptptrlgksvkqttvEEKTRVMQLEEELALRKAEVEElQVRFQRGSSGS 499
Cdd:PRK02224 282 RDLRERLEELE---EERDDLLAEAGLDD------------------ADAEAVEARREELEDRDEELRD-RLEECRVAAQA 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 500 ATDAEDGEpgiTSETLVLREQllsvGRERREESSQLRERYEASLSTSQKEIERLKAITErqgqEISDLKQRLQQA--TRE 577
Cdd:PRK02224 340 HNEEAESL---REDADDLEER----AEELREEAAELESELEEAREAVEDRREEIEELEE----EIEELRERFGDApvDLG 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 578 NMEmmdswkAKLDALVGDHQRALEELkASLTTDCGSGEINGGEGEGSL-----PEMRAALEG------------LKMEHQ 640
Cdd:PRK02224 409 NAE------DFLEELREERDELRERE-AELEATLRTARERVEEAEALLeagkcPECGQPVEGsphvetieedreRVEELE 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 641 LELENLKAKHE-----IDAAVMAKEREDLRSRLQELRDQLEDSEENWKIQVETKSNQ----------HTLEIKEVSEKLQ 705
Cdd:PRK02224 482 AELEDLEEEVEeveerLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERaeelreraaeLEAEAEEKREAAA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 706 KAELRivdldkSQEEREKVNQLLKEQLMLAEK--KMVDYEALQKAEAQSRAEILSLQEKL-----RVTENRLQAVEADHT 778
Cdd:PRK02224 562 EAEEE------AEEAREEVAELNSKLAELKERieSLERIRTLLAAIADAEDEIERLREKRealaeLNDERRERLAEKRER 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 779 TQDVNMIENNDNSDEKVKLKQNVEETLEKLtkrEKEVSTLTTQVDALKTQITALEEKVrlgeKTADGLIKEKTRLEAELE 858
Cdd:PRK02224 636 KRELEAEFDEARIEEAREDKERAEEYLEQV---EEKLDELREERDDLQAEIGAVENEL----EELEELRERREALENRVE 708
|
..
gi 1207177222 859 TM 860
Cdd:PRK02224 709 AL 710
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
395-684 |
3.28e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.09 E-value: 3.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 395 ESNLQQVRAMLASTQKdkmELANQLEEEKRKVEDLQFRVEEESITKGDLEVRGRLQPTPTRLgksvkqttVEEKTRVMQL 474
Cdd:COG3206 163 EQNLELRREEARKALE---FLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQL--------SELESQLAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 475 EEELALRKAEVEELQVRFQRGSSGSATDAEDgePGITSetlvLREQLLSVGRERREESSQLRERYEaslstsqkEIERLK 554
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQS--PVIQQ----LRAQLAELEAELAELSARYTPNHP--------DVIALR 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 555 AiterqgqEISDLKQRLQQATRENMEMMDSWKAKLDALVGDHQRALEELKASLTTdcgsgeinggegegsLPEMRAALEG 634
Cdd:COG3206 298 A-------QIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAE---------------LPELEAELRR 355
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1207177222 635 LkmehQLELENLKAKHeidaavmakerEDLRSRLQELRDQLEDSEENWKI 684
Cdd:COG3206 356 L----EREVEVARELY-----------ESLLQRLEEARLAEALTVGNVRV 390
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
353-921 |
3.66e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 3.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 353 EQLLAERDLE--RAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAM---LASTQKDKMELANQLEEEKRKVE 427
Cdd:TIGR02169 288 EQLRVKEKIGelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELereIEEERKRRDKLTEEYAELKEELE 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 428 DLQFRVEEESITKGDLevrgrlqptptrlgksvKQTTVEEKTRVMQLEEELALRKAEVEELQVRFQRGSSGSA------T 501
Cdd:TIGR02169 368 DLRAELEEVDKEFAET-----------------RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAdlnaaiA 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 502 DAEDGEPGITSETLVLREQlLSVGRERREESSQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATRE---- 577
Cdd:TIGR02169 431 GIEAKINELEEEKEDKALE-IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERvrgg 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 578 --NMEMMDSWK--------------------------AKLDALV----GDHQRALEELK---ASLTTDCGSGEINGGEGE 622
Cdd:TIGR02169 510 raVEEVLKASIqgvhgtvaqlgsvgeryataievaagNRLNNVVveddAVAKEAIELLKrrkAGRATFLPLNKMRDERRD 589
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 623 GSLPEMRA----ALEGLKMEHQLE------------LENLKAKHEI--------------------------------DA 654
Cdd:TIGR02169 590 LSILSEDGvigfAVDLVEFDPKYEpafkyvfgdtlvVEDIEAARRLmgkyrmvtlegelfeksgamtggsraprggilFS 669
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 655 AVMAKEREDLRSRLQELRDQLEDSEENwKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLdksQEEREKVNQLLKEQLML 734
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSE-LRRIENRLDELSQELSDASRKIGEIEKEIEQL---EQEEEKLKERLEELEED 745
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 735 AEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIEN--NDNSDEKVKLKQNVEETLEKLTKRE 812
Cdd:TIGR02169 746 LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAelSKLEEEVSRIEARLREIEQKLNRLT 825
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 813 KEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLL 892
Cdd:TIGR02169 826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905
|
650 660
....*....|....*....|....*....
gi 1207177222 893 lesprhsagvdRDLSREVHRAEWRMKEQK 921
Cdd:TIGR02169 906 -----------EELEAQIEKKRKRLSELK 923
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
743-992 |
4.45e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 4.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 743 EALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTqdVNMIENNDNSDEKVKLKQ----NVEETLEKLTKREKEVSTL 818
Cdd:COG4913 613 AALEAELAELEEELAEAEERLEALEAELDALQERREA--LQRLAEYSWDEIDVASAEreiaELEAELERLDASSDDLAAL 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 819 TTQVDALKTQITALEEKVrlgektaDGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLLLESPRH 898
Cdd:COG4913 691 EEQLEELEAELEELEEEL-------DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAV 763
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 899 SAGVDRDLSREVhraewrmkeQKLQDDIKTLREKLLLLGRERLSPDHRRYSMMDPSASD-TEVARLRQRLLNT-----ED 972
Cdd:COG4913 764 ERELRENLEERI---------DALRARLNRAEEELERAMRAFNREWPAETADLDADLESlPEYLALLDRLEEDglpeyEE 834
|
250 260
....*....|....*....|..
gi 1207177222 973 ALRNALEHN--QHVDQLVQAMR 992
Cdd:COG4913 835 RFKELLNENsiEFVADLLSKLR 856
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
323-861 |
6.55e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.09 E-value: 6.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 323 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYAtETESNLQQVR 402
Cdd:pfam01576 76 ILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLE-DQNSKLSKER 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 403 AMLastQKDKMELANQLEEEKRKVEDLQFRVEEESITKGDLEVrgrlqptptRLGKSVKQTTVEEKTR------VMQLEE 476
Cdd:pfam01576 155 KLL---EERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEE---------RLKKEEKGRQELEKAKrklegeSTDLQE 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 477 ELALRKAEVEELQVRFQRGSSGSATDAEDGEPGITSETLVLR-----EQLLSVGRERREESSQLRERYEASLSTSQKEIE 551
Cdd:pfam01576 223 QIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKkirelEAQISELQEDLESERAARNKAEKQRRDLGEELE 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 552 RLKAITE--------------RQGQEISDLKQRLQQATRenmemmdSWKAKLDALVGDHQRALEELKASLttdcgsgeIN 617
Cdd:pfam01576 303 ALKTELEdtldttaaqqelrsKREQEVTELKKALEEETR-------SHEAQLQEMRQKHTQALEELTEQL--------EQ 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 618 GGEGEGSLPEMRAALEGLKMEHQLELENL-KAKHEIDaavmaKEREDLRSRLQELRDQLEDSEEnwkiqvetksnqhtlE 696
Cdd:pfam01576 368 AKRNKANLEKAKQALESENAELQAELRTLqQAKQDSE-----HKRKKLEGQLQELQARLSESER---------------Q 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 697 IKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRaeiLSLQEKLRVTEnrlqavead 776
Cdd:pfam01576 428 RAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQK---LNLSTRLRQLE--------- 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 777 httqdvnmienndnsDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQ-------ITALEE------------KVR 837
Cdd:pfam01576 496 ---------------DERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKleedagtLEALEEgkkrlqrelealTQQ 560
|
570 580
....*....|....*....|....*.
gi 1207177222 838 LGEKTA--DGLIKEKTRLEAELETMT 861
Cdd:pfam01576 561 LEEKAAayDKLEKTKNRLQQELDDLL 586
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
629-863 |
7.48e-05 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 45.96 E-value: 7.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 629 RAALEGLKMEHQLELENLKAKHEIDAAVMA--KEREDLRSRLQELRDQLEdseenwkiQVETKSNQHTLEIKEVSEKLQK 706
Cdd:pfam15905 55 KVKSLELKKKSQKNLKESKDQKELEKEIRAlvQERGEQDKRLQALEEELE--------KVEAKLNAAVREKTSLSASVAS 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 707 AELRIVDLDK---------SQEEREKVNQLLKEQLMLAEKKM---------------VDYEALQKAEAQSRAEILSLQEK 762
Cdd:pfam15905 127 LEKQLLELTRvnellkakfSEDGTQKKMSSLSMELMKLRNKLeakmkevmakqegmeGKLQVTQKNLEHSKGKVAQLEEK 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 763 LRVTEnRLQAVEADHTTQDVNMIENNDNSDEKV-KLKQNVEETLEKLTKREKEVSTLTTQVDA----LKTQITALEEKVR 837
Cdd:pfam15905 207 LVSTE-KEKIEEKSETEKLLEYITELSCVSEQVeKYKLDIAQLEELLKEKNDEIESLKQSLEEkeqeLSKQIKDLNEKCK 285
|
250 260 270
....*....|....*....|....*....|
gi 1207177222 838 LGEKTADGLIKE----KTRLEAELETMTKK 863
Cdd:pfam15905 286 LLESEKEELLREyeekEQTLNAELEELKEK 315
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
694-931 |
7.55e-05 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 46.67 E-value: 7.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 694 TLEIKEVSEKLQKAEL---RIVDLDKSQEEREKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRL 770
Cdd:pfam07111 52 SLELEGSQALSQQAELisrQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVR 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 771 QaveadhttqdvNMIENNDNSDEKVKLKQnvEETLEKLTK-REKEVSTLTTQVDALKTQITALEEKvRLGEktadglIKE 849
Cdd:pfam07111 132 K-----------NLEEGSQRELEEIQRLH--QEQLSSLTQaHEEALSSLTSKAEGLEKSLNSLETK-RAGE------AKQ 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 850 KTRLEAELETMtkkshdaSGQLVNISQELlkkerslnELRVLLLESPRHSAGvdRDLSREVHRAEWRMKEQKLQDDIKTL 929
Cdd:pfam07111 192 LAEAQKEAELL-------RKQLSKTQEEL--------EAQVTLVESLRKYVG--EQVPPEVHSQTWELERQELLDTMQHL 254
|
..
gi 1207177222 930 RE 931
Cdd:pfam07111 255 QE 256
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
527-942 |
7.98e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 46.74 E-value: 7.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 527 ERREESSQLRERYEASLSTSQKEIERLKAITERQGQEISdlkqrLQQATRENMEM-MDSWKAKLDALVGDHQRALEELKA 605
Cdd:pfam10174 95 QDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELF-----LLRKTLEEMELrIETQKQTLGARDESIKKLLEMLQS 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 606 SLTTDCGSGEINGGEGEGSLPEMRAA-LEGLKmeHQLELENLKAkheidaavmakeREDLRSRLQELRDQledseenwki 684
Cdd:pfam10174 170 KGLPKKSGEEDWERTRRIAEAEMQLGhLEVLL--DQKEKENIHL------------REELHRRNQLQPDP---------- 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 685 qVETKSNQHTLEIKEVseklqkaelRIVDLDKSQEEREKVNQLLKEQLMLA----EKKMVDYEALQKAEAQSRAEILSLQ 760
Cdd:pfam10174 226 -AKTKALQTVIEMKDT---------KISSLERNIRDLEDEVQMLKTNGLLHtedrEEEIKQMEVYKSHSKFMKNKIDQLK 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 761 EKLRVTENRLQAVEADHTTQdvnmieNNDNSDEKvklkQNVEETLEKLTKREKEVSTLTTQVDALKTQitaLEEKVRLGE 840
Cdd:pfam10174 296 QELSKKESELLALQTKLETL------TNQNSDCK----QHIEVLKESLTAKEQRAAILQTEVDALRLR---LEEKESFLN 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 841 KTADGLI---KEKTRLEAELETMT-------KKSHDASGQLVNISQELLKKERSLNELRVLLLESPRHSAGVDRDLS--- 907
Cdd:pfam10174 363 KKTKQLQdltEEKSTLAGEIRDLKdmldvkeRKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTtle 442
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1207177222 908 ---REVHRAEWRMKEQKLQDD-------------IKTLREKLLLLGRERLS 942
Cdd:pfam10174 443 ealSEKERIIERLKEQREREDrerleeleslkkeNKDLKEKVSALQPELTE 493
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
630-856 |
1.01e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 630 AALEGLKMEHQLELENLKAkhEIDAAvmAKEREDLRSRLQELRDQLEDSEENwKIQVETKSNQHTLEIKEVSEKLQKAEL 709
Cdd:COG4942 16 AAQADAAAEAEAELEQLQQ--EIAEL--EKELAALKKEEKALLKQLAALERR-IAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 710 RIVDLDKSQEE-REKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENN 788
Cdd:COG4942 91 EIAELRAELEAqKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1207177222 789 DNSDEKVKLKQNVEETLEKLTK----REKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAE 856
Cdd:COG4942 171 AERAELEALLAELEEERAALEAlkaeRQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
660-893 |
1.63e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 660 EREDLRSRLQELRDQLEDSEENWKIQVETKSNQHTLE-IKEVSEKLQKAELRIVDLDksqeerekvnqllkeqlmlAEKK 738
Cdd:COG4913 219 EEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpIRELAERYAAARERLAELE-------------------YLRA 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 739 MVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIE-----NNDNSDEKVKLKQNVEETLEKLTKREK 813
Cdd:COG4913 280 ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEleaqiRGNGGDRLEQLEREIERLERELEERER 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 814 EVSTLTTQVDALKTQIT----ALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQEL--LKKERSLNE 887
Cdd:COG4913 360 RRARLEALLAALGLPLPasaeEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIasLERRKSNIP 439
|
....*.
gi 1207177222 888 LRVLLL 893
Cdd:COG4913 440 ARLLAL 445
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
726-889 |
1.89e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 726 QLLKEQLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEAdhttqdvnMIENNDNSDEKVKLKQNVEET- 804
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK--------LLQLLPLYQELEALEAELAELp 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 805 --LEKLTKREKEVSTLTTQVDALKTQITALEEKVrlgektADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKE 882
Cdd:COG4717 146 erLEELEERLEELRELEEELEELEAELAELQEEL------EELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219
|
....*..
gi 1207177222 883 RSLNELR 889
Cdd:COG4717 220 EELEELE 226
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
341-583 |
2.01e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.43 E-value: 2.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 341 LQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARhlqyATETESNLQQVRAMLASTQKDKMELANQLE 420
Cdd:TIGR02168 773 AEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE----AANLRERLESLERRIAATERRLEDLEEQIE 848
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 421 EEKRKVEDLQFRVEEESITKGDLEvrgrlqptptrlgksvKQTTVEEKtRVMQLEEELALRKAEVEELQVRfQRGSSGSA 500
Cdd:TIGR02168 849 ELSEDIESLAAEIEELEELIEELE----------------SELEALLN-ERASLEEALALLRSELEELSEE-LRELESKR 910
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 501 TDAEDGEPGITS--ETLVLREQLLSVGRERREEssQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATREN 578
Cdd:TIGR02168 911 SELRRELEELREklAQLELRLEGLEVRIDNLQE--RLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVN 988
|
....*
gi 1207177222 579 MEMMD 583
Cdd:TIGR02168 989 LAAIE 993
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
357-868 |
2.21e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.52 E-value: 2.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 357 AERDLERAEVAKATSHicEVEKELAALKARHLQYATETESNLQQVRA--MLASTQKDKMELANQLEEEKRKVEDLQFRVE 434
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAE--EAKKAAEAAKAEAEAAADEAEAAEEKAEAaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAE 1401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 435 EESITKGDLEVRGRLQPTPTRLGKSVKQTTVEEKTRvMQLEEElalRKAEVEELQVRFQRGSSGSATDAEDG----EPGI 510
Cdd:PTZ00121 1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK-KKAEEA---KKADEAKKKAEEAKKAEEAKKKAEEAkkadEAKK 1477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 511 TSETLVLREQLLSVGRERREESSQLRERYEAslstsQKEIERLKAITERQGQEisdlkqRLQQAtrENMEMMDSWKAKLD 590
Cdd:PTZ00121 1478 KAEEAKKADEAKKKAEEAKKKADEAKKAAEA-----KKKADEAKKAEEAKKAD------EAKKA--EEAKKADEAKKAEE 1544
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 591 ALVGDHQRALEELKASlttdcgsgeinggEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVMAKEREDLRSRLQE 670
Cdd:PTZ00121 1545 KKKADELKKAEELKKA-------------EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE 1611
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 671 LRDQLED--SEENWKIQVETKSNQHTLEIKEVSEKLQKAELRivdldkSQEEREKVNQllKEQLMLAEKKMVDYEALQKA 748
Cdd:PTZ00121 1612 AKKAEEAkiKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELK------KAEEENKIKA--AEEAKKAEEDKKKAEEAKKA 1683
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 749 EAQSRAEILSL----QEKLRVTENRLQAVEADHTTQDVNMiENNDNSDEKVKLKQNVEE---TLEKLTKREKEvstlTTQ 821
Cdd:PTZ00121 1684 EEDEKKAAEALkkeaEEAKKAEELKKKEAEEKKKAEELKK-AEEENKIKAEEAKKEAEEdkkKAEEAKKDEEE----KKK 1758
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1207177222 822 VDALKTQITALEEKVRLGEKTA--DGLIKEKTRLEAELETMTKKSHDAS 868
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEKEAVieEELDEEDEKRRMEVDKKIKDIFDNF 1807
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
629-940 |
2.22e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 44.89 E-value: 2.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 629 RAALEGLKMEHQLELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLEDSEENwkiqvETKSNQHTLEIKEVSEKLqkAE 708
Cdd:pfam07888 43 RAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREK-----HEELEEKYKELSASSEEL--SE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 709 LRIVDLDKSQEEREKVNQLLKEQLMLAEKKM---VDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMI 785
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEDIKTLTQRVLereTELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 786 ENNDNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKE-------KTRLEAELE 858
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEElssmaaqRDRTQAELH 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 859 TMTKKSHDASGQLVNISQELLKKERSLNELRvlllESPRHSAGVDRD----LSREVHRAEWRMKEQKLQddiktlREKLL 934
Cdd:pfam07888 276 QARLQAAQLTLQLADASLALREGRARWAQER----ETLQQSAEADKDriekLSAELQRLEERLQEERME------REKLE 345
|
....*..
gi 1207177222 935 L-LGRER 940
Cdd:pfam07888 346 VeLGREK 352
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
343-814 |
2.31e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.52 E-value: 2.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 343 EALKEKQQhiEQLLAERDLERAEVAKATSHIcEVEKELAALKARHLQYATETESNLQQVRAMLASTQKDKMELAnqleEE 422
Cdd:PTZ00121 1460 EEAKKKAE--EAKKADEAKKKAEEAKKADEA-KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA----EE 1532
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 423 KRKVEDLQfrvEEESITKGDlEVRGRLQPTPTRLGKSVKQTTVEEKTRVMQLEEELALRKAE---VEELQVRFQRGSSGS 499
Cdd:PTZ00121 1533 AKKADEAK---KAEEKKKAD-ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEearIEEVMKLYEEEKKMK 1608
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 500 ATDAEDGEPG-ITSETL-------VLREQLLSVGRERREESSQLRERYE-----ASLSTSQKEIERLKAITERQGQEisD 566
Cdd:PTZ00121 1609 AEEAKKAEEAkIKAEELkkaeeekKKVEQLKKKEAEEKKKAEELKKAEEenkikAAEEAKKAEEDKKKAEEAKKAEE--D 1686
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 567 LKQRLQQATRENMEMMDSwkAKLDALVGDHQRALEELKAS---LTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLEL 643
Cdd:PTZ00121 1687 EKKAAEALKKEAEEAKKA--EELKKKEAEEKKKAEELKKAeeeNKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 644 ENLKAKHEIDAAVMAKEREDLR----SRLQELRDQLEDSEENWKIQVEtKSNQHTLEIKEVSEKLQKAELRIVDLDKSQE 719
Cdd:PTZ00121 1765 EEEKKAEEIRKEKEAVIEEELDeedeKRRMEVDKKIKDIFDNFANIIE-GGKEGNLVINDSKEMEDSAIKEVADSKNMQL 1843
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 720 EREKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRA----EILSLQEKLRVTENRLQAVEADHTTQDVNMIENNDNSDEKV 795
Cdd:PTZ00121 1844 EEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEddeeEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDE 1923
|
490
....*....|....*....
gi 1207177222 796 KLKQNVEETLEKLTKREKE 814
Cdd:PTZ00121 1924 YIKRDAEETREEIIKISKK 1942
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
652-892 |
2.60e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 652 IDAAVMAKEREDLRSRLQEL-RDQLEDSEENWKI-------QVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREK 723
Cdd:pfam02463 159 EEEAAGSRLKRKKKEALKKLiEETENLAELIIDLeelklqeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 724 VNQLLKEQLMLAEKK------MVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENNDNSDEKVKL 797
Cdd:pfam02463 239 IDLLQELLRDEQEEIesskqeIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 798 KQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRlgEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQE 877
Cdd:pfam02463 319 SEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEE--EELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEE 396
|
250
....*....|....*
gi 1207177222 878 LLKKERSLNELRVLL 892
Cdd:pfam02463 397 LELKSEEEKEAQLLL 411
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
466-933 |
2.60e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.04 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 466 EEKTRVMQLEEEL-ALRKAEVE------ELQVRFQRGSSGSATDAEDGEPGITSETLVLREQLLSVGRE------RREES 532
Cdd:TIGR00606 259 HNLSKIMKLDNEIkALKSRKKQmekdnsELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQREleklnkERRLL 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 533 SQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATRENMEMMDSWKAKLDALVgdhQRALEELKASLTTDCG 612
Cdd:TIGR00606 339 NQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLV---IERQEDEAKTAAQLCA 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 613 SGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVMA--KEREDLRSRLQELRDQLEDSEENWKiQVETKS 690
Cdd:TIGR00606 416 DLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKelQQLEGSSDRILELDQELRKAERELS-KAEKNS 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 691 NQHTLEIKEVSEKLQKAEL--RIVDLDKSQEEREKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRAEILSL--------- 759
Cdd:TIGR00606 495 LTETLKKEVKSLQNEKADLdrKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnkkq 574
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 760 --------QEKLRVTENRLQAV--EADHTTQDVNMIENNDNSDEKVKLK-----------QNVEETLEKLTKR----EKE 814
Cdd:TIGR00606 575 ledwlhskSKEINQTRDRLAKLnkELASLEQNKNHINNELESKEEQLSSyedklfdvcgsQDEESDLERLKEEieksSKQ 654
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 815 VSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLLle 894
Cdd:TIGR00606 655 RAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLA-- 732
|
490 500 510
....*....|....*....|....*....|....*....
gi 1207177222 895 sPRHSAGVDRdlsREVHRAEWRMKEQKLQDDIKTLREKL 933
Cdd:TIGR00606 733 -PGRQSIIDL---KEKEIPELRNKLQKVNRDIQRLKNDI 767
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
642-836 |
2.63e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 642 ELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLEDseenwkiqVETKSNQHTLEIKEVSEKLQKAElrivdldksqeer 721
Cdd:COG1579 21 RLEHRLKELPAELAELEDELAALEARLEAAKTELED--------LEKEIKRLELEIEEVEARIKKYE------------- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 722 ekvnqllkEQLMLAeKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHttqdvnmienndnSDEKVKLKQNV 801
Cdd:COG1579 80 --------EQLGNV-RNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEEL-------------AELEAELAELE 137
|
170 180 190
....*....|....*....|....*....|....*
gi 1207177222 802 EETLEKLTKREKEVSTLTTQVDALKTQITALEEKV 836
Cdd:COG1579 138 AELEEKKAELDEELAELEAELEELEAEREELAAKI 172
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
540-979 |
3.84e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 3.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 540 EASLSTSQKEIERLKA-ITERQGQEISDLKQRLQQATRENmemmDSWKAKLDALVGDHQRaLEELKASLTT-DCGSGEIN 617
Cdd:COG4717 48 LERLEKEADELFKPQGrKPELNLKELKELEEELKEAEEKE----EEYAELQEELEELEEE-LEELEAELEElREELEKLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 618 GGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVMaKEREDLRSRLQELRDQLEDSEENWKIQVETKSNQHTLEI 697
Cdd:COG4717 123 KLLQLLPLYQELEALEAELAELPERLEELEERLEELRELE-EELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 698 KEVSEKLQKAELRIVDLDKSQEE-REKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEA- 775
Cdd:COG4717 202 EELQQRLAELEEELEEAQEELEElEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFl 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 776 --------------DHTTQDVNMIENNDNSDEKVKLKQNVEETLEKLT-KREKEVSTLTTQVDALKTQITALEEKVRLGE 840
Cdd:COG4717 282 vlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLAALGlPPDLSPEELLELLDRIEELQELLREAEELEE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 841 KTAdgLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLLLEsprhSAGVDRDLSREVHRAEWRMKEQ 920
Cdd:COG4717 362 ELQ--LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEE----LLGELEELLEALDEEELEEELE 435
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 1207177222 921 KLQDDIKTLREKLLLLGRERLSPDHRRYSMmdpsASDTEVARLRQRLLNTEDALRNALE 979
Cdd:COG4717 436 ELEEELEELEEELEELREELAELEAELEQL----EEDGELAELLQELEELKAELRELAE 490
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
651-972 |
5.93e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 43.88 E-value: 5.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 651 EIDAAVMAKERED-------LRSRLQELRDQLEDSEENWKIQVETKSNQhTLEIKEVSEKLQ-----KAELRIVDLDKSQ 718
Cdd:PRK02224 191 QLKAQIEEKEEKDlherlngLESELAELDEEIERYEEQREQARETRDEA-DEVLEEHEERREeletlEAEIEDLRETIAE 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 719 EEREK------VNQLLKEQLMLAEKK--MVDYEALQKAEAQSRAEILS-LQEKLRVTENRLQAVEAD---HTTQDVNMIE 786
Cdd:PRK02224 270 TEREReelaeeVRDLRERLEELEEERddLLAEAGLDDADAEAVEARREeLEDRDEELRDRLEECRVAaqaHNEEAESLRE 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 787 NNDNSDEKVKLKQNVEETLEKltkrekEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHD 866
Cdd:PRK02224 350 DADDLEERAEELREEAAELES------ELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDE 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 867 ASGQLVNISQELLKKERSLNELRVLLLESPRHSAGVDRDLSREVHRA-EWRMKEQKLQDDIKTLREKllllgRERLSPDH 945
Cdd:PRK02224 424 LREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIeEDRERVEELEAELEDLEEE-----VEEVEERL 498
|
330 340
....*....|....*....|....*..
gi 1207177222 946 RRYSmmDPSASDTEVARLRQRLLNTED 972
Cdd:PRK02224 499 ERAE--DLVEAEDRIERLEERREDLEE 523
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
629-837 |
6.32e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 6.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 629 RAALEGLKMEHQlELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLEDSEEnwkiQVETKSNQHTLEikEVSEKLQKAE 708
Cdd:COG4913 609 RAKLAALEAELA-ELEEELAEAEERLEALEAELDALQERREALQRLAEYSWD----EIDVASAEREIA--ELEAELERLD 681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 709 LRIVDLDKSQEEREKVNQLLKEqlmlAEKKmvdYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENn 788
Cdd:COG4913 682 ASSDDLAALEEQLEELEAELEE----LEEE---LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE- 753
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1207177222 789 dnsdekvKLKQNVEETLEKLTKREkevstLTTQVDALKTQITALEEKVR 837
Cdd:COG4913 754 -------RFAAALGDAVERELREN-----LEERIDALRARLNRAEEELE 790
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
324-577 |
6.42e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 6.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 324 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHICEVEKELAALKARHLQYAT------ETESN 397
Cdd:COG4913 622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDDLAAleeqleELEAE 700
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 398 LQQVRAMLASTQKDKMELANQLEEEKRKVEDLQFRVEEESiTKGDLEVRGRLQPTPTRLGKSVKQTTVEEK--TRVMQLE 475
Cdd:COG4913 701 LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAE-DLARLELRALLEERFAAALGDAVERELRENleERIDALR 779
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 476 EELALRKAEVEELQVRFQR----GSSGSATDAEDGEpgitsETLVLREQLLSVGRERREEssQLREryeaslstsqkeie 551
Cdd:COG4913 780 ARLNRAEEELERAMRAFNRewpaETADLDADLESLP-----EYLALLDRLEEDGLPEYEE--RFKE-------------- 838
|
250 260
....*....|....*....|....*.
gi 1207177222 552 rlkAITERQGQEISDLKQRLQQATRE 577
Cdd:COG4913 839 ---LLNENSIEFVADLLSKLRRAIRE 861
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
518-975 |
6.77e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 6.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 518 REQLLSVGRERREEssqLRERYeASLSTSQKEIERLKAITERQ-------------GQEISDLKQRLQQATREnmemmds 584
Cdd:PRK04863 784 REKRIEQLRAEREE---LAERY-ATLSFDVQKLQRLHQAFSRFigshlavafeadpEAELRQLNRRRVELERA------- 852
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 585 wkakLDALVGDHQRALEELKASlttdcgsgeinggegegslpemRAALEGLkmehqlelenlkAKHEIDAAVMAkeREDL 664
Cdd:PRK04863 853 ----LADHESQEQQQRSQLEQA----------------------KEGLSAL------------NRLLPRLNLLA--DETL 892
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 665 RSRLQELRDQLEDSEENwkiQVETKSNQHTLE-IKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEKKMVDYE 743
Cdd:PRK04863 893 ADRVEEIREQLDEAEEA---KRFVQQHGNALAqLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRA 969
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 744 ALQKAEAQSR-AEILSLQEKLRVtenRLQAVEADHTTQDVNMIENNDNSDEK----VKLKQNVEETLEKLTKREKEVSTL 818
Cdd:PRK04863 970 HFSYEDAAEMlAKNSDLNEKLRQ---RLEQAEQERTRAREQLRQAQAQLAQYnqvlASLKSSYDAKRQMLQELKQELQDL 1046
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 819 TTQVDAlktqitALEEKVRLGEKTADG-----------LIKEKTRLEAELETMTKK-------SHDASGQLVN---ISQE 877
Cdd:PRK04863 1047 GVPADS------GAEERARARRDELHArlsanrsrrnqLEKQLTFCEAEMDNLTKKlrklerdYHEMREQVVNakaGWCA 1120
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 878 LLKK------ERSLN--ELRVLLLESPRhsAGVDRDLSR---EVHRAEWRMKEQKLQDDIKTLREKLLL------LGRER 940
Cdd:PRK04863 1121 VLRLvkdngvERRLHrrELAYLSADELR--SMSDKALGAlrlAVADNEHLRDVLRLSEDPKRPERKVQFyiavyqHLRER 1198
|
490 500 510
....*....|....*....|....*....|....*....
gi 1207177222 941 LSPDHRRYSmmDP----SASDTEVARLRQRLLNTEDALR 975
Cdd:PRK04863 1199 IRQDIIRTD--DPveaiEQMEIELSRLTEELTSREQKLA 1235
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
339-844 |
7.49e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.80 E-value: 7.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 339 TALQEALKEKQQHIEQLL-------AERDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQKD 411
Cdd:TIGR00618 375 HTLTQHIHTLQQQKTTLTqklqslcKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCE 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 412 KM------ELANQLEEEKRKVEDLQFRVEEESITKGDLEVRGRLQPTPTRLgksvkqttVEEKTRVMQLEEELALrkaEV 485
Cdd:TIGR00618 455 KLekihlqESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCP--------LCGSCIHPNPARQDID---NP 523
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 486 EELQVRFQRGSSGSA---TDAEDGEPGITSETLVLREQLLSVGRERREES--SQLRERYEASLSTSQKEIERLKaiteRQ 560
Cdd:TIGR00618 524 GPLTRRMQRGEQTYAqleTSEEDVYHQLTSERKQRASLKEQMQEIQQSFSilTQCDNRSKEDIPNLQNITVRLQ----DL 599
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 561 GQEISDLKQRLQQATRENMEMMDSWKAKLDALVGDHQRALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQ 640
Cdd:TIGR00618 600 TEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQ 679
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 641 LELENLKAKHEidaaVMAKEREDLRSRLQELRDQLEDSEENWK----IQVETKSNQHTLEIKEVSEKLQKAELRivdldk 716
Cdd:TIGR00618 680 LALQKMQSEKE----QLTYWKEMLAQCQTLLRELETHIEEYDRefneIENASSSLGSDLAAREDALNQSLKELM------ 749
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 717 sQEEREKVNQLLKEQLMLAEKKMVDYEALQKaEAQSRAEILSLQEKLRVTENRLQAVEADHTTQ-DVNMIENNDNSDEKV 795
Cdd:TIGR00618 750 -HQARTVLKARTEAHFNNNEEVTAALQTGAE-LSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEiPSDEDILNLQCETLV 827
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1207177222 796 KLKQNVEETLEKLTKREKEVSTLTTQV-DALKTQITALEEKVRLGEKTAD 844
Cdd:TIGR00618 828 QEEEQFLSRLEEKSATLGEITHQLLKYeECSKQLAQLTQEQAKIIQLSDK 877
|
|
| TACC_C |
pfam05010 |
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a ... |
547-728 |
9.68e-04 |
|
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organizing centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1). TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis. Maskin is also found to bind CPEB and elF-4E. Interestingly, the functional homolog (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organization of bipolar spindles.
Pssm-ID: 461517 [Multi-domain] Cd Length: 201 Bit Score: 41.59 E-value: 9.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 547 QKEIERLKAITERQGQEISDLKQRLQQATRENMEM---MDSWKAKLDALVGDHQRALEELKASLttdcGSGEINGGEGEG 623
Cdd:pfam05010 7 DAALEKARNEIEEKELEINELKAKYEELRRENLEMrkiVAEFEKTIAQMIEEKQKQKELEHAEI----QKVLEEKDQALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 624 SLPEMRAALEGL--KMEHQLE-LENLKAKHEidaaVMAKEREDLRSRLQelrdQLEDSEENWKIQVETKSNQHTLEIKEV 700
Cdd:pfam05010 83 DLNSVEKSFSDLfkRYEKQKEvISGYKKNEE----SLKKCAQDYLARIK----KEEQRYQALKAHAEEKLDQANEEIAQV 154
|
170 180 190
....*....|....*....|....*....|....*....
gi 1207177222 701 SEK-----------LQKAELRIVDLDKSQEEREKVNQLL 728
Cdd:pfam05010 155 RSKakaetaalqasLRKEQMKVQSLERQLEQKTKENEEL 193
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
340-577 |
1.42e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 340 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARhlqyATETESNLQQVRAMLASTQKDKMELANQL 419
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR----IRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 420 EEEKRKVEDL---QFRVEEESITK--------GDLEVRGRLQPTPTRLGKSVKQTTVEEKTRVMQLEEELALRKAEVEEL 488
Cdd:COG4942 100 EAQKEELAELlraLYRLGRQPPLAlllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 489 QVRFQRgssgsatdaedgepgitsetlvLREQLLSVGRERREESSQLRERYEAslstSQKEIERLKAITERQGQEISDLK 568
Cdd:COG4942 180 LAELEE----------------------ERAALEALKAERQKLLARLEKELAE----LAAELAELQQEAEELEALIARLE 233
|
....*....
gi 1207177222 569 QRLQQATRE 577
Cdd:COG4942 234 AEAAAAAER 242
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
352-679 |
1.46e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 352 IEQLLAERDLERAEVAKATSHICEVEKELAALKARH-----LQYATETESNLQQVRAMLASTQKDK----------MELA 416
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAELDALQERRealqrLAEYSWDEIDVASAEREIAELEAELerldassddlAALE 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 417 NQLEEEKRKVEDLQFRVEeesitkgdlevrgrlqptptrlgksvkqttvEEKTRVMQLEEELALRKAEVEELQVRFQRGS 496
Cdd:COG4913 692 EQLEELEAELEELEEELD-------------------------------ELKGEIGRLEKELEQAEEELDELQDRLEAAE 740
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 497 SGSATDAEDGepgitsetlvLREQLLSVGRERREEssQLRERYEaslstsqkeiERLKAITERQGQEISDLKQRLQQATR 576
Cdd:COG4913 741 DLARLELRAL----------LEERFAAALGDAVER--ELRENLE----------ERIDALRARLNRAEEELERAMRAFNR 798
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 577 ENMEMMDSWKAKLDALvGDHQRALEELKASlttdcgsgeinggegegSLPEMRAALEGLKMEHQLE-LENLKAKheidaa 655
Cdd:COG4913 799 EWPAETADLDADLESL-PEYLALLDRLEED-----------------GLPEYEERFKELLNENSIEfVADLLSK------ 854
|
330 340
....*....|....*....|....
gi 1207177222 656 vMAKEREDLRSRLQELRDQLEDSE 679
Cdd:COG4913 855 -LRRAIREIKERIDPLNDSLKRIP 877
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
343-989 |
1.48e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.73 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 343 EALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQKDKMElanQLEEE 422
Cdd:TIGR00606 248 DPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKER---ELVDC 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 423 KRKVEDLQFRVEEESITKGDLEVR-GRLQPTPTRLGKSVKQTTVEEKTRVMQLE----EELALRKAEVEELQVRFQRGSS 497
Cdd:TIGR00606 325 QRELEKLNKERRLLNQEKTELLVEqGRLQLQADRHQEHIRARDSLIQSLATRLEldgfERGPFSERQIKNFHTLVIERQE 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 498 GSATDAEDgepgitsetlvLREQLLSVGRERREESSQLRERYEASLSTSQKEIERLkaitERQGQEISDLKQRLQQATRE 577
Cdd:TIGR00606 405 DEAKTAAQ-----------LCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEIL----EKKQEELKFVIKELQQLEGS 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 578 NMEMMdswkaKLDALVGDHQRALEELKASLTTDCGSGEINGGEGEGslpemraaLEGLKMEHQLELENLKAKHEIDA--- 654
Cdd:TIGR00606 470 SDRIL-----ELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEK--------ADLDRKLRKLDQEMEQLNHHTTTrtq 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 655 -AVMAKEREDLRSRLQELRDQLEDSEEN------WKIQVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREKVNQL 727
Cdd:TIGR00606 537 mEMLTKDKMDKDEQIRKIKSRHSDELTSllgyfpNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELES 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 728 LKEQLMLAEKKMVDYEALQKAEAqsraEILSLQEKLRVTENRLQAVEADHTTQDVNMIENNDNSDEKVKLKQNVEETlek 807
Cdd:TIGR00606 617 KEEQLSSYEDKLFDVCGSQDEES----DLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQT--- 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 808 ltkrEKEVSTLttqvdalktqITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKshdASGQlvniSQELLKKERSLNE 887
Cdd:TIGR00606 690 ----EAELQEF----------ISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGL---APGR----QSIIDLKEKEIPE 748
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 888 LRVLLLESPRHSAGVDRDLSREVHRAEWRMKEQKLQDDIKT---LREKLlllgRERLSPDHRRY----SMMDPSASDTEV 960
Cdd:TIGR00606 749 LRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTdvtIMERF----QMELKDVERKIaqqaAKLQGSDLDRTV 824
|
650 660
....*....|....*....|....*....
gi 1207177222 961 ARLRQRLLNTEDALRNALEHNQHVDQLVQ 989
Cdd:TIGR00606 825 QQVNQEKQEKQHELDTVVSKIELNRKLIQ 853
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
600-738 |
1.48e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 41.93 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 600 LEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLEDSE 679
Cdd:smart00787 149 LDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLKKLLQEIMIKVKKLE 228
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1207177222 680 EnwkiqVETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREKVN----QLLKEQLMLAEKK 738
Cdd:smart00787 229 E-----LEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTfkeiEKLKEQLKLLQSL 286
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
789-994 |
1.48e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 789 DNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDAS 868
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 869 GQLVNISQELLKKERSlNELRVLLleSPRHSAGVDRDLSREVHRAEWRMKE-QKLQDDIKTLREKLLLLGRER------- 940
Cdd:COG4942 104 EELAELLRALYRLGRQ-PPLALLL--SPEDFLDAVRRLQYLKYLAPARREQaEELRADLAELAALRAELEAERaeleall 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1207177222 941 --LSPDHRRYSmMDPSASDTEVARLRQRLLNTEDALRNALEHNQHVDQLVQAMRTR 994
Cdd:COG4942 181 aeLEEERAALE-ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
713-888 |
1.52e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 713 DLDKSQEEREKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENNDNSD 792
Cdd:COG3883 24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 793 --EKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQ 870
Cdd:COG3883 104 ylDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183
|
170
....*....|....*...
gi 1207177222 871 LVNISQELLKKERSLNEL 888
Cdd:COG3883 184 LAQLSAEEAAAEAQLAEL 201
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
696-885 |
1.60e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 42.47 E-value: 1.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 696 EIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLM---------------LAEKKMVDYEALQKAEAQSRAE----- 755
Cdd:pfam01576 13 ELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQaetelcaeaeemrarLAARKQELEEILHELESRLEEEeersq 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 756 ------------ILSLQEKLRVTENRLQAVEADHTT---------QDVNMIE--NNDNSDEKVKLKQNVEETLEKLTKRE 812
Cdd:pfam01576 93 qlqnekkkmqqhIQDLEEQLDEEEAARQKLQLEKVTteakikkleEDILLLEdqNSKLSKERKLLEERISEFTSNLAEEE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1207177222 813 KEVSTLTTQVDALKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSL 885
Cdd:pfam01576 173 EKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEEL 245
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
659-924 |
2.09e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.34 E-value: 2.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 659 KEREDLRSRLQELRDQLEDSEENWKIQVETKSNqhtlEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEKK 738
Cdd:TIGR00606 712 KSTESELKKKEKRRDEMLGLAPGRQSIIDLKEK----EIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVC 787
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 739 MVDYEALQKAEAQSRaeilSLQEKLRVTENRLQAVEADHTTQDVNMiENNDNSDEKVKLKQNVEETLEKLTKREKEVSTL 818
Cdd:TIGR00606 788 LTDVTIMERFQMELK----DVERKIAQQAAKLQGSDLDRTVQQVNQ-EKQEKQHELDTVVSKIELNRKLIQDQQEQIQHL 862
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 819 TTQVDALKTqitaleEKVRLGE--KTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELRVLLLESP 896
Cdd:TIGR00606 863 KSKTNELKS------EKLQIGTnlQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSN 936
|
250 260 270
....*....|....*....|....*....|
gi 1207177222 897 RHSAGVDRDLSREVHRAEWRMK--EQKLQD 924
Cdd:TIGR00606 937 KKAQDKVNDIKEKVKNIHGYMKdiENKIQD 966
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
745-889 |
2.12e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 745 LQKAEAQSRAEILSLQEKLRVTENRLQAVEADHTTQDVNMIENNDNSDEKVKLKQNVEETLEKLTKrEKEVSTLTTQVDA 824
Cdd:COG1579 22 LEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN-NKEYEALQKEIES 100
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1207177222 825 LKTQITALEEKVRLGEKTADGLIKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNELR 889
Cdd:COG1579 101 LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAER 165
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
625-816 |
2.72e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 2.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 625 LPEMRAALEglkmEHQLELENLKAKHEI-----DAAVMAKEREDLRSRLQELRDQLEDSEENWKiQVETKSNQHTLEIKE 699
Cdd:COG3206 184 LPELRKELE----EAEAALEEFRQKNGLvdlseEAKLLLQQLSELESQLAEARAELAEAEARLA-ALRAQLGSGPDALPE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 700 VSEKLQKAELRIvDLDKSQEEREKVNQLLKE---QLMLAEKKMVDYEALQKAEAQSRaeILSLQEKLRVTENRLQAVEAD 776
Cdd:COG3206 259 LLQSPVIQQLRA-QLAELEAELAELSARYTPnhpDVIALRAQIAALRAQLQQEAQRI--LASLEAELEALQAREASLQAQ 335
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1207177222 777 HTTQDVNMIENNDNSDEKVKLKQNVE---ETLEKLTKREKEVS 816
Cdd:COG3206 336 LAQLEARLAELPELEAELRRLEREVEvarELYESLLQRLEEAR 378
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
343-780 |
3.22e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.29 E-value: 3.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 343 EALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQKDKMELANQLEEE 422
Cdd:COG4717 149 EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 423 KRKVEDLQFRVEEESitkgdlevrgrlqptptrlgksvkqttveektrvmQLEEELALRKAEVEELQVRFQRGSSGSATD 502
Cdd:COG4717 229 LEQLENELEAAALEE-----------------------------------RLKEARLLLLIAAALLALLGLGGSLLSLIL 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 503 AEDGEPGITSETLVLREQLLSVGRERREESSQLRERYEASLSTSQKEIERLKA----ITERQGQEISDLKQRLQQATREN 578
Cdd:COG4717 274 TIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAalglPPDLSPEELLELLDRIEELQELL 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 579 MEMMDswkAKLDALVGDHQRALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLkmEHQLELENLKAKHEIDAAvma 658
Cdd:COG4717 354 REAEE---LEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEEL--EEQLEELLGELEELLEAL--- 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 659 kEREDLRSRLQELRDQLEDSEENWK-IQVETKSNQHTLEIKEVSEKLQKAELRIvdldksQEEREKVNQLLKE--QLMLA 735
Cdd:COG4717 426 -DEEELEEELEELEEELEELEEELEeLREELAELEAELEQLEEDGELAELLQEL------EELKAELRELAEEwaALKLA 498
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1207177222 736 EKKMvdYEALQKAEAQSRAEILSLQEKL--RVTENRLQAVEADHTTQ 780
Cdd:COG4717 499 LELL--EEAREEYREERLPPVLERASEYfsRLTDGRYRLIRIDEDLS 543
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
348-726 |
3.80e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.48 E-value: 3.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 348 KQQHIEQLLAERDLERAEVAKATSHICEVEKELAALK---ARHLQYATETESNlqqvrAMLASTQKDKMELANQLEEEKR 424
Cdd:PRK04863 784 REKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSrfiGSHLAVAFEADPE-----AELRQLNRRRVELERALADHES 858
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 425 KVEDLQFRVEEesiTKGDLEVRGRLQPTPTRLgksvKQTTVEEktRVMQLEEELAlrKAEVEELQVRfQRGSsgsatdae 504
Cdd:PRK04863 859 QEQQQRSQLEQ---AKEGLSALNRLLPRLNLL----ADETLAD--RVEEIREQLD--EAEEAKRFVQ-QHGN-------- 918
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 505 dgepgitseTLVLREQLLSVGRERREESSQLRERYEASLSTSQKEIERLKAITErqgqeisdLKQRL--------QQATR 576
Cdd:PRK04863 919 ---------ALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTE--------VVQRRahfsyedaAEMLA 981
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 577 ENMEMMDSWKAKLDALVGDHQRALEELKASlttdcgsgeinggegEGSLPEMRAALEGLKMEHQLELENLK-AKHEIDA- 654
Cdd:PRK04863 982 KNSDLNEKLRQRLEQAEQERTRAREQLRQA---------------QAQLAQYNQVLASLKSSYDAKRQMLQeLKQELQDl 1046
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1207177222 655 --AVMAKEREDLRSRLQELRDQLEDSEENwKIQVETKSNQHTLEIKEVSEKLQKAElrivdlDKSQEEREKVNQ 726
Cdd:PRK04863 1047 gvPADSGAEERARARRDELHARLSANRSR-RNQLEKQLTFCEAEMDNLTKKLRKLE------RDYHEMREQVVN 1113
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
396-933 |
3.82e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 41.43 E-value: 3.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 396 SNLQQVRAMLASTQKDKMELANQLEEEKRKVEDLQFRVEEESITKGDLEVRgrlqptptrlgksvKQTTVEEKTRVMQLE 475
Cdd:PRK01156 183 SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDD--------------YNNLKSALNELSSLE 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 476 EELALRKAEVEELQVRFQrgssgSATDAEDGEPGITSETLVLREQLLSVGRERREESSQLR---ERYEASLSTSQKEIER 552
Cdd:PRK01156 249 DMKNRYESEIKTAESDLS-----MELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKndiENKKQILSNIDAEINK 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 553 LKAITERQGQEISDLKQRLQQATRenmemMDSWKAKLDALVGDHQ------RALEELKASLTTDCGSGEINGGEGEGSLP 626
Cdd:PRK01156 324 YHAIIKKLSVLQKDYNDYIKKKSR-----YDDLNNQILELEGYEMdynsylKSIESLKKKIEEYSKNIERMSAFISEILK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 627 EMRAALEGLKMEHQlELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLEDSEENWKIQV------ETKSNQ----HTLE 696
Cdd:PRK01156 399 IQEIDPDAIKKELN-EINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVcgttlgEEKSNHiinhYNEK 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 697 IKEVSEKLQKAELRIVDLDksqeerEKVNQLLKEQLMLAEKKMVDYEALQKAEAQSRAEIlslqEKLRVTENRLQAVEAD 776
Cdd:PRK01156 478 KSRLEEKIREIEIEVKDID------EKIVDLKKRKEYLESEEINKSINEYNKIESARADL----EDIKIKINELKDKHDK 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 777 HttqdvNMIENNDNSDEKVKLKQNVEETLEKLTKREK-EVSTLTTQVDALKTQITALEEkvRLGEktadgLIKEKTRLEA 855
Cdd:PRK01156 548 Y-----EEIKNRYKSLKLEDLDSKRTSWLNALAVISLiDIETNRSRSNEIKKQLNDLES--RLQE-----IEIGFPDDKS 615
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207177222 856 ELETMTKKSHDASGQLVNISQELLKKERSLNELRVLLLESPRHSAGVDrdlSREVHRAEWRMKEQKLQDDIKTLREKL 933
Cdd:PRK01156 616 YIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEID---SIIPDLKEITSRINDIEDNLKKSRKAL 690
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
538-837 |
4.27e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.31 E-value: 4.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 538 RYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATRENMEMMDSWKAKldalvgdhqralEELKASLTtdcgsgein 617
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAE------------TELCAEAE--------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 618 ggegegslpEMRAALEGLKMEHQLELENLKAK---HEIDAAVMAKEREDLRSRLQELRDQLEDSEE-NWKIQVETKSnqh 693
Cdd:pfam01576 61 ---------EMRARLAARKQELEEILHELESRleeEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAaRQKLQLEKVT--- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 694 tleikeVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEKKMVDYE----ALQKAEAQSRAEILSLQEKLRVTENR 769
Cdd:pfam01576 129 ------TEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEekakSLSKLKNKHEAMISDLEERLKKEEKG 202
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1207177222 770 LQAVEADHTTQDVnmiENNDNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVR 837
Cdd:pfam01576 203 RQELEKAKRKLEG---ESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIR 267
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
687-888 |
5.31e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 40.77 E-value: 5.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 687 ETKSNQHTLEIKEVSEKLQKAELRIVDLDKSQEEREKVNQLLKEQLMLAEKkmvdyealqkaeaqsraEILSLQEKLRVT 766
Cdd:TIGR04523 32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQ-----------------QIKDLNDKLKKN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 767 ENRLQAVEADhttqdvnMIENNDNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVdalKTQITALEEKVRLGEKTADGL 846
Cdd:TIGR04523 95 KDKINKLNSD-------LSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKF---LTEIKKKEKELEKLNNKYNDL 164
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1207177222 847 IKEKTRLEAELETMTKKSHDASGQLVNISQELLKKERSLNEL 888
Cdd:TIGR04523 165 KKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNL 206
|
|
| ATP-synt_Fo_b |
cd06503 |
F-type ATP synthase, membrane subunit b; Membrane subunit b is a component of the Fo complex ... |
526-605 |
6.55e-03 |
|
F-type ATP synthase, membrane subunit b; Membrane subunit b is a component of the Fo complex of FoF1-ATP synthase. The F-type ATP synthases (FoF1-ATPase) consist of two structural domains: the F1 (assembly factor one) complex containing the soluble catalytic core, and the Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F1 is composed of alpha (or A), beta (B), gamma (C), delta (D) and epsilon (E) subunits with a stoichiometry of 3:3:1:1:1, while Fo consists of the three subunits a, b, and c (1:2:10-14). An oligomeric ring of 10-14 c subunits (c-ring) make up the Fo rotor. The flux of protons through the ATPase channel (Fo) drives the rotation of the c-ring, which in turn is coupled to the rotation of the F1 complex gamma subunit rotor due to the permanent binding between the gamma and epsilon subunits of F1 and the c-ring of Fo. The F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. The F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. This group also includes F-ATP synthase that has also been found in the archaea Candidatus Methanoperedens.
Pssm-ID: 349951 [Multi-domain] Cd Length: 132 Bit Score: 37.80 E-value: 6.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 526 RERREESSQLRERYEASLSTSQKEIERLKAITERQGQEISDlkQRLQQATRENMEMMDSWKAKLDAlvgDHQRALEELKA 605
Cdd:cd06503 43 EKAKEEAEELLAEYEEKLAEARAEAQEIIEEARKEAEKIKE--EILAEAKEEAERILEQAKAEIEQ---EKEKALAELRK 117
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
638-890 |
8.48e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 40.27 E-value: 8.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 638 EHQLELENLKAKHEIDAAVMAKEREDLRSRLQELRDQLEDSEENWKIQVETKSNQ-HTLEIKEVSEKLQKAELRIVDLDK 716
Cdd:PLN02939 70 DENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQlSDFQLEDLVGMIQNAEKNILLLNQ 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 717 SQ-EEREKVNQLLKE------QLMLAEKKMVDYEALQK--AEAQSRAEILSLQ-EKLRVTENRLQAVEADH--------- 777
Cdd:PLN02939 150 ARlQALEDLEKILTEkealqgKINILEMRLSETDARIKlaAQEKIHVEILEEQlEKLRNELLIRGATEGLCvhslskeld 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 778 TTQDVNMIENNDNSDEKVKLkQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKV-RLGEKTADGLIKEKTRLEAE 856
Cdd:PLN02939 230 VLKEENMLLKDDIQFLKAEL-IEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsKLSPLQYDCWWEKVENLQDL 308
|
250 260 270
....*....|....*....|....*....|....*...
gi 1207177222 857 LETMTKKSHDASgQLVNISQELLKK----ERSLNELRV 890
Cdd:PLN02939 309 LDRATNQVEKAA-LVLDQNQDLRDKvdklEASLKEANV 345
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
530-865 |
8.99e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 40.21 E-value: 8.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 530 EESSQLRERYEASLSTSQKEIERLKAITERQGQEISDLKQRLQQATREnmeMMDSWKAKLDALVGDHQRALEELKasltt 609
Cdd:pfam12128 247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRT---LDDQWKEKRDELNGELSAADAAVA----- 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 610 dcgsgeinggegegslpemraaleglKMEHQLELenlkakheIDAAVMAKEREDLRSRLQELrdqleDSEENWKIQVETK 689
Cdd:pfam12128 319 --------------------------KDRSELEA--------LEDQHGAFLDADIETAAADQ-----EQLPSWQSELENL 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 690 SNQH---TLEIKEVSEKLQKAELRIV-----DLDKSQEEREKVNQLLKEQLMLAEKkmvDYEALQKA-EAQSRAEILSLQ 760
Cdd:pfam12128 360 EERLkalTGKHQDVTAKYNRRRSKIKeqnnrDIAGIKDKLAKIREARDRQLAVAED---DLQALESElREQLEAGKLEFN 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 761 E-----KLRVTENRLQAVEADHTTQDVNMIENNDNSDEKVKlkqnveetlEKLTKREKEVSTLTTQVDALKTQITALEEK 835
Cdd:pfam12128 437 EeeyrlKSRLGELKLRLNQATATPELLLQLENFDERIERAR---------EEQEAANAEVERLQSELRQARKRRDQASEA 507
|
330 340 350
....*....|....*....|....*....|
gi 1207177222 836 VRLGEKTadgLIKEKTRLEAELETMTKKSH 865
Cdd:pfam12128 508 LRQASRR---LEERQSALDELELQLFPQAG 534
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
519-774 |
9.33e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.11 E-value: 9.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 519 EQLLSVGRERR-EESSQLRERYEASLSTSQKEIERLKAITERQGQEI--SDLKQRLQQATRENMEMMDSWKAKLDALVGD 595
Cdd:pfam17380 307 EKAREVERRRKlEEAEKARQAEMDRQAAIYAEQERMAMERERELERIrqEERKRELERIRQEEIAMEISRMRELERLQME 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 596 HQRALEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVMAKEREDLRSRLQELRDQL 675
Cdd:pfam17380 387 RQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLR 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207177222 676 EDSEENWKIQVETKsnqhtleiKEVSEKLQKAELRIVDLDKSQEER-------EKVNQLLKEQLMLAEKKMVDYEALQKA 748
Cdd:pfam17380 467 QQEEERKRKKLELE--------KEKRDRKRAEEQRRKILEKELEERkqamieeERKRKLLEKEMEERQKAIYEEERRREA 538
|
250 260
....*....|....*....|....*.
gi 1207177222 749 EAQSRAEIlSLQEKLRVTENRLQAVE 774
Cdd:pfam17380 539 EEERRKQQ-EMEERRRIQEQMRKATE 563
|
|
| |
