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Conserved domains on  [gi|1207182124|ref|XP_021333723|]
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zinc finger homeobox protein 3 isoform X1 [Danio rerio]

Protein Classification

homeobox domain-containing protein( domain architecture ID 13130865)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
2772-2828 3.15e-20

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 86.40  E-value: 3.15e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 2772 KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK 2828
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
Homeodomain pfam00046
Homeodomain;
2381-2437 5.93e-20

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 85.63  E-value: 5.93e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 2381 RSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK 2437
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
Homeodomain pfam00046
Homeodomain;
3070-3126 1.36e-17

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 79.08  E-value: 1.36e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 3070 KRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKK 3126
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2283-2339 3.31e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


:

Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 69.59  E-value: 3.31e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124  2283 NKRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNTLFKER 2339
Cdd:smart00389    1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
COG5576 super family cl35021
Homeodomain-containing transcription factor [Transcription];
2723-2868 7.33e-11

Homeodomain-containing transcription factor [Transcription];


The actual alignment was detected with superfamily member COG5576:

Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 63.22  E-value: 7.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 2723 IPQMSSNSATSPSTPTSTMNSLKRKLEEKAGTSPGESDSMNSGeePQRDKRLRTTitPEQLEILYQKYLLDSNPTRKMLD 2802
Cdd:COG5576      7 QPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSS--PPKSKRRRTT--DEQLMVLEREFEINPYPSSITRI 82

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 2803 HIAHEVGLKKRVVQVWFQNTRARERK---GQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEA 2868
Cdd:COG5576     83 KLSLLLNMPPKSVQIWFQNKRAKEKKkrsGKVEQRPGEEEADLAKIGSLSTGQISIIETLEFSRTSYEE 151
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 3228-3401 4.14e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.45  E-value: 4.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3228 FDTPALQALNLQSGYPNLQGIPPVLL-PGVGGPSIpgfnsSNSALTPPKPPNLLNMPGASVPSPSLPTSGL----PNKTP 3302
Cdd:pfam05109  434 LNTTGFAAPNTTTGLPSSTHVPTNLTaPASTGPTV-----STADVTSPTPAGTTSGASPVTPSPSPRDNGTeskaPDMTS 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3303 SSSSLASPSPAQASTSVAHSSPTPTSTTNSL-MTQPGARPEAPkdrdperarekekpkekAEKSSTPSSAGGTPAPSTSA 3381
Cdd:pfam05109  509 PTSAVTTPTPNATSPTPAVTTPTPNATSPTLgKTSPTSAVTTP-----------------TPNATSPTPAVTTPTPNATI 571

                          170       180
                   ....*....|....*....|
gi 1207182124 3382 ASAKKEKTDTAVpatSMPTP 3401
Cdd:pfam05109  572 PTLGKTSPTSAV---TTPTP 588
PHA00732 super family cl20114
hypothetical protein
 1339-1391 7.43e-03

hypothetical protein


The actual alignment was detected with superfamily member PHA00732:

Pssm-ID: 177300  Cd Length: 79  Bit Score: 38.22  E-value: 7.43e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207182124 1339 MYQCPYCKFSNTDLNRLRMHVMTQHSVQpmfRCPLCQDM---LNNKVHLQFHLTHL 1391
Cdd:PHA00732     1 MFKCPICGFTTVTLFALKQHARRNHTLT---KCPVCNKSyrrLNQHFYSQYDIEHL 53
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
2772-2828 3.15e-20

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 86.40  E-value: 3.15e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 2772 KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK 2828
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
Homeodomain pfam00046
Homeodomain;
2381-2437 5.93e-20

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 85.63  E-value: 5.93e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 2381 RSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK 2437
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2380-2436 3.81e-18

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 80.76  E-value: 3.81e-18
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124  2380 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKAR 2436
Cdd:smart00389    1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
Homeodomain pfam00046
Homeodomain;
3070-3126 1.36e-17

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 79.08  E-value: 1.36e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 3070 KRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKK 3126
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 2381-2438 1.98e-17

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 78.82  E-value: 1.98e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1207182124 2381 RSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKN 2438
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 2772-2830 3.29e-17

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 78.05  E-value: 3.29e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 2772 KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQ 2830
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2772-2827 8.30e-17

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 76.91  E-value: 8.30e-17
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207182124  2772 KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARER 2827
Cdd:smart00389    2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2283-2339 3.31e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 69.59  E-value: 3.31e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124  2283 NKRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNTLFKER 2339
Cdd:smart00389    1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 2284-2342 7.97e-14

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 68.42  E-value: 7.97e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 2284 KRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRN 2342
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 3069-3125 9.32e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 68.05  E-value: 9.32e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124  3069 QKRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEK 3125
Cdd:smart00389    1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 3070-3128 1.88e-13

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 67.27  E-value: 1.88e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 3070 KRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKAK 3128
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
Homeodomain pfam00046
Homeodomain;
2284-2343 5.13e-13

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 65.98  E-value: 5.13e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 2284 KRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNTlfkeRQRNK 2343
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNR----RAKWK 56
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2380-2453 1.34e-12

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 68.23  E-value: 1.34e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 2380 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGD---GVKEGDRRE 2453
Cdd:COG5576     51 PKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVEqrpGEEEADLAK 127
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
3031-3137 6.92e-11

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 63.22  E-value: 6.92e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3031 FENENMIDYSETSSLADPCSPspgasgsrsidsgdrpgQKRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPK 3110
Cdd:COG5576     30 REVEAADSEMKLERKQDGSSP-----------------PKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPP 92

                           90       100
                   ....*....|....*....|....*...
gi 1207182124 3111 RVVQVWFQNARAKEKKA-KLSMAKHFGI 3137
Cdd:COG5576     93 KSVQIWFQNKRAKEKKKrSGKVEQRPGE 120
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2723-2868 7.33e-11

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 63.22  E-value: 7.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 2723 IPQMSSNSATSPSTPTSTMNSLKRKLEEKAGTSPGESDSMNSGeePQRDKRLRTTitPEQLEILYQKYLLDSNPTRKMLD 2802
Cdd:COG5576      7 QPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSS--PPKSKRRRTT--DEQLMVLEREFEINPYPSSITRI 82

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 2803 HIAHEVGLKKRVVQVWFQNTRARERK---GQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEA 2868
Cdd:COG5576     83 KLSLLLNMPPKSVQIWFQNKRAKEKKkrsGKVEQRPGEEEADLAKIGSLSTGQISIIETLEFSRTSYEE 151
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2284-2343 1.55e-07

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 53.59  E-value: 1.55e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 2284 KRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNtlfkERQRNK 2343
Cdd:COG5576     52 KSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQN----KRAKEK 107
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 3228-3401 4.14e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.45  E-value: 4.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3228 FDTPALQALNLQSGYPNLQGIPPVLL-PGVGGPSIpgfnsSNSALTPPKPPNLLNMPGASVPSPSLPTSGL----PNKTP 3302
Cdd:pfam05109  434 LNTTGFAAPNTTTGLPSSTHVPTNLTaPASTGPTV-----STADVTSPTPAGTTSGASPVTPSPSPRDNGTeskaPDMTS 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3303 SSSSLASPSPAQASTSVAHSSPTPTSTTNSL-MTQPGARPEAPkdrdperarekekpkekAEKSSTPSSAGGTPAPSTSA 3381
Cdd:pfam05109  509 PTSAVTTPTPNATSPTPAVTTPTPNATSPTLgKTSPTSAVTTP-----------------TPNATSPTPAVTTPTPNATI 571

                          170       180
                   ....*....|....*....|
gi 1207182124 3382 ASAKKEKTDTAVpatSMPTP 3401
Cdd:pfam05109  572 PTLGKTSPTSAV---TTPTP 588
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 3243-3385 3.26e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 3.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3243 PNLQGIPPVLLPGVGGPSIPGFNSSNSALTPPKPP---NLLNMPGASVPSPSLPTSGLPNKTPSSSSLASPSPAQASTSV 3319
Cdd:PHA03307   136 EMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRqaaLPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISA 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3320 AHSSPTPT----------------STTNSLMTQPGARPEAPKDRD-----PERAREKEKPKEKAEKSSTPSSAGGTPAPS 3378
Cdd:PHA03307   216 SASSPAPApgrsaaddagasssdsSSSESSGCGWGPENECPLPRPapitlPTRIWEASGWNGPSSRPGPASSSSSPRERS 295


                   ....*..
gi 1207182124 3379 TSAASAK 3385
Cdd:PHA03307   296 PSPSPSS 302
PHA00732 PHA00732
hypothetical protein
 1339-1391 7.43e-03

hypothetical protein


Pssm-ID: 177300  Cd Length: 79  Bit Score: 38.22  E-value: 7.43e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207182124 1339 MYQCPYCKFSNTDLNRLRMHVMTQHSVQpmfRCPLCQDM---LNNKVHLQFHLTHL 1391
Cdd:PHA00732     1 MFKCPICGFTTVTLFALKQHARRNHTLT---KCPVCNKSyrrLNQHFYSQYDIEHL 53
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
2772-2828 3.15e-20

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 86.40  E-value: 3.15e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 2772 KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK 2828
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
Homeodomain pfam00046
Homeodomain;
2381-2437 5.93e-20

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 85.63  E-value: 5.93e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 2381 RSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK 2437
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2380-2436 3.81e-18

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 80.76  E-value: 3.81e-18
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124  2380 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKAR 2436
Cdd:smart00389    1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
Homeodomain pfam00046
Homeodomain;
3070-3126 1.36e-17

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 79.08  E-value: 1.36e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 3070 KRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKK 3126
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 2381-2438 1.98e-17

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 78.82  E-value: 1.98e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1207182124 2381 RSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKN 2438
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 2772-2830 3.29e-17

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 78.05  E-value: 3.29e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 2772 KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQ 2830
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2772-2827 8.30e-17

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 76.91  E-value: 8.30e-17
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207182124  2772 KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARER 2827
Cdd:smart00389    2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2283-2339 3.31e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 69.59  E-value: 3.31e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124  2283 NKRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNTLFKER 2339
Cdd:smart00389    1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 2284-2342 7.97e-14

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 68.42  E-value: 7.97e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 2284 KRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRN 2342
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 3069-3125 9.32e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 68.05  E-value: 9.32e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124  3069 QKRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEK 3125
Cdd:smart00389    1 KRRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 3070-3128 1.88e-13

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 67.27  E-value: 1.88e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 3070 KRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKAK 3128
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
Homeodomain pfam00046
Homeodomain;
2284-2343 5.13e-13

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 65.98  E-value: 5.13e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 2284 KRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNTlfkeRQRNK 2343
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNR----RAKWK 56
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2380-2453 1.34e-12

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 68.23  E-value: 1.34e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1207182124 2380 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGD---GVKEGDRRE 2453
Cdd:COG5576     51 PKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVEqrpGEEEADLAK 127
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
3031-3137 6.92e-11

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 63.22  E-value: 6.92e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3031 FENENMIDYSETSSLADPCSPspgasgsrsidsgdrpgQKRFRTQMTNLQLKVLKSCFSDYRTPTMLECEVLGNDIGLPK 3110
Cdd:COG5576     30 REVEAADSEMKLERKQDGSSP-----------------PKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPP 92

                           90       100
                   ....*....|....*....|....*...
gi 1207182124 3111 RVVQVWFQNARAKEKKA-KLSMAKHFGI 3137
Cdd:COG5576     93 KSVQIWFQNKRAKEKKKrSGKVEQRPGE 120
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2723-2868 7.33e-11

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 63.22  E-value: 7.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 2723 IPQMSSNSATSPSTPTSTMNSLKRKLEEKAGTSPGESDSMNSGeePQRDKRLRTTitPEQLEILYQKYLLDSNPTRKMLD 2802
Cdd:COG5576      7 QPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSS--PPKSKRRRTT--DEQLMVLEREFEINPYPSSITRI 82

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 2803 HIAHEVGLKKRVVQVWFQNTRARERK---GQFRAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEA 2868
Cdd:COG5576     83 KLSLLLNMPPKSVQIWFQNKRAKEKKkrsGKVEQRPGEEEADLAKIGSLSTGQISIIETLEFSRTSYEE 151
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2284-2343 1.55e-07

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 53.59  E-value: 1.55e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 2284 KRPRTRITDDQLRVLRQYFDINNSPNEEQIKEMADKSGLPQKVIKHWFRNtlfkERQRNK 2343
Cdd:COG5576     52 KSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQN----KRAKEK 107
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 3228-3401 4.14e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.45  E-value: 4.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3228 FDTPALQALNLQSGYPNLQGIPPVLL-PGVGGPSIpgfnsSNSALTPPKPPNLLNMPGASVPSPSLPTSGL----PNKTP 3302
Cdd:pfam05109  434 LNTTGFAAPNTTTGLPSSTHVPTNLTaPASTGPTV-----STADVTSPTPAGTTSGASPVTPSPSPRDNGTeskaPDMTS 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3303 SSSSLASPSPAQASTSVAHSSPTPTSTTNSL-MTQPGARPEAPkdrdperarekekpkekAEKSSTPSSAGGTPAPSTSA 3381
Cdd:pfam05109  509 PTSAVTTPTPNATSPTPAVTTPTPNATSPTLgKTSPTSAVTTP-----------------TPNATSPTPAVTTPTPNATI 571

                          170       180
                   ....*....|....*....|
gi 1207182124 3382 ASAKKEKTDTAVpatSMPTP 3401
Cdd:pfam05109  572 PTLGKTSPTSAV---TTPTP 588
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 3283-3403 5.71e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 5.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3283 PGASVPSPSL---------PTSGLPNKTPSSSSLASPSPAQASTSVAH-SSPTPTSTTNS---LMTQPGARPEAPKDRDP 3349
Cdd:pfam05109  425 PESTTTSPTLnttgfaapnTTTGLPSSTHVPTNLTAPASTGPTVSTADvTSPTPAGTTSGaspVTPSPSPRDNGTESKAP 504

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1207182124 3350 ERAREKEKPKEKAEKSSTPSSAGGTPAPSTSAASAKKEKTDTAV----PATSMPTPGM 3403
Cdd:pfam05109  505 DMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVttptPNATSPTPAV 562
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 3243-3385 3.26e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 3.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3243 PNLQGIPPVLLPGVGGPSIPGFNSSNSALTPPKPP---NLLNMPGASVPSPSLPTSGLPNKTPSSSSLASPSPAQASTSV 3319
Cdd:PHA03307   136 EMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRqaaLPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISA 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3320 AHSSPTPT----------------STTNSLMTQPGARPEAPKDRD-----PERAREKEKPKEKAEKSSTPSSAGGTPAPS 3378
Cdd:PHA03307   216 SASSPAPApgrsaaddagasssdsSSSESSGCGWGPENECPLPRPapitlPTRIWEASGWNGPSSRPGPASSSSSPRERS 295


                   ....*..
gi 1207182124 3379 TSAASAK 3385
Cdd:PHA03307   296 PSPSPSS 302
PHA00732 PHA00732
hypothetical protein
 1339-1391 7.43e-03

hypothetical protein


Pssm-ID: 177300  Cd Length: 79  Bit Score: 38.22  E-value: 7.43e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207182124 1339 MYQCPYCKFSNTDLNRLRMHVMTQHSVQpmfRCPLCQDM---LNNKVHLQFHLTHL 1391
Cdd:PHA00732     1 MFKCPICGFTTVTLFALKQHARRNHTLT---KCPVCNKSyrrLNQHFYSQYDIEHL 53
PHA03247 PHA03247
large tegument protein UL36; Provisional
 3249-3402 9.68e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 9.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207182124 3249 PPVLLPGVGGPSIP-----GFNSSNSALTPPKPPNLLNMPGASVPSPSLPTSGLPNKTpsssslaspspaqASTSVAHSS 3323
Cdd:PHA03247  2712 PHALVSATPLPPGPaaarqASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAP-------------APPAAPAAG 2778

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207182124 3324 PTPTSTTNSLMTQPGARPEAPKDRDPERArekEKPKEKAEKSSTPSSAGGTPAPSTSAASAKKEKTDTAVPATSMPTPG 3402
Cdd:PHA03247  2779 PPRRLTRPAVASLSESRESLPSPWDPADP---PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG 2854
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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