|
Name |
Accession |
Description |
Interval |
E-value |
| TACC_C |
pfam05010 |
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a ... |
2763-2963 |
3.55e-109 |
|
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organizing centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1). TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis. Maskin is also found to bind CPEB and elF-4E. Interestingly, the functional homolog (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organization of bipolar spindles.
Pssm-ID: 461517 [Multi-domain] Cd Length: 201 Bit Score: 346.66 E-value: 3.55e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2763 FQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQA 2842
Cdd:pfam05010 1 YSQKDMDAALEKARNEIEEKELEINELKAKYEELRRENLEMRKIVAEFEKTIAQMIEEKQKQKELEHAEIQKVLEEKDQA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2843 LADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQ 2922
Cdd:pfam05010 81 LADLNSVEKSFSDLFKRYEKQKEVISGYKKNEESLKKCAQDYLARIKKEEQRYQALKAHAEEKLDQANEEIAQVRSKAKA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456157 2923 EQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI 2963
Cdd:pfam05010 161 ETAALQASLRKEQMKVQSLERQLEQKTKENEELTKICDELI 201
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
24-488 |
1.92e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 60.72 E-value: 1.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 24 PPNPEPTQRTLSAQTPRSA-QPPGNSQNIKRKQQDTPGSPdhrdASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRK 102
Cdd:PHA03247 2556 PPAAPPAAPDRSVPPPRPApRPSEPAVTSRARRPDAPPQS----ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSP 2631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 103 DPQGARGPEGSLLPSPPPSQEREHPSssmpfaecPPEGCLASPAAAPEDGPQTQSPRREPAPnapgdiaaafPAERDSST 182
Cdd:PHA03247 2632 SPAANEPDPHPPPTVPPPERPRDDPA--------PGRVSRPRRARRLGRAAQASSPPQRPRR----------RAARPTVG 2693
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 183 PYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEA------------ 250
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPttagppapappa 2773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 251 --AGGFPPAESRQGVASVQVT------PEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTD 322
Cdd:PHA03247 2774 apAAGPPRRLTRPAVASLSESreslpsPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 323 -------DLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGH 395
Cdd:PHA03247 2854 gsvapggDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 396 PQTGMRGTKPNQVVCVAAGGQPEGGLPvSPEPSLLTPTEEAHPaSSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSAD 475
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAVP-QPWLGALVPGRVAVP-RFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSL 3011
|
490
....*....|...
gi 1370456157 476 AAKEVVDAGLVGL 488
Cdd:PHA03247 3012 ALHEETDPPPVSL 3024
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2696-2961 |
7.72e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 58.61 E-value: 7.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2696 AQKLQEElefaIMRIEALKLA---RQIALASRSHQDAKREAAHPTD----VSISKTALYSRigTAEVEKPAGLLFQQPDL 2768
Cdd:PTZ00121 1120 AKKKAED----ARKAEEARKAedaRKAEEARKAEDAKRVEIARKAEdarkAEEARKAEDAK--KAEAARKAEEVRKAEEL 1193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2769 DSALQIARAEIITK---EREVSEWKdKYEESRR-----EVMEMRKIVAEYEKTIAQMIEDEQR---EKSVSHQTVQQLVL 2837
Cdd:PTZ00121 1194 RKAEDARKAEAARKaeeERKAEEAR-KAEDAKKaeavkKAEEAKKDAEEAKKAEEERNNEEIRkfeEARMAHFARRQAAI 1272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2838 EKEQAL-AD--LNSVEKSLADLFRRYEKMKEVLEGFRKNEEvlKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIA 2914
Cdd:PTZ00121 1273 KAEEARkADelKKAEEKKKADEAKKAEEKKKADEAKKKAEE--AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA 1350
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1370456157 2915 QVRGKAQQeqaahqasLRKEQLRVDALERTLEQKNKEIEELTKICDE 2961
Cdd:PTZ00121 1351 EAEAAADE--------AEAAEEKAEAAEKKKEEAKKKADAAKKKAEE 1389
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2761-2967 |
1.08e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.77 E-value: 1.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2761 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKT---IAQM-IEDEQREKSVshQTVQQLV 2836
Cdd:PRK03918 184 FIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeeIEELeKELESLEGSK--RKLEEKI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2837 LEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANA----- 2911
Cdd:PRK03918 262 RELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDE-LREIEKRLSRLEEEINGIEERIKELEEkeerl 340
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370456157 2912 ------------EIAQVRGKAQQEQAAHQASLRKEQLR-------VDALERTLEQKNKEIEELTKICDELIAKMG 2967
Cdd:PRK03918 341 eelkkklkelekRLEELEERHELYEEAKAKKEELERLKkrltgltPEKLEKELEELEKAKEEIEEEISKITARIG 415
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2768-2961 |
1.58e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2768 LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKT---IAQMIEDEQREKsvshqtvQQLVLEKEQALA 2844
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKElyaLANEISRLEQQK-------QILRERLANLER 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2845 DLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVH---AEEKLDRANAEIAQVRGKAQ 2921
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRleeLEEQLETLRSKVAQLELQIA 396
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1370456157 2922 qeqaahqaSLRKEQLRVDA----LERTLEQKNKEIEELTKICDE 2961
Cdd:TIGR02168 397 --------SLNNEIERLEArlerLEDRRERLQQEIEELLKKLEE 432
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2688-2964 |
3.83e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.10 E-value: 3.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2688 AEKnpplfAQKLQEELEfaimRIEALKLARQIALASRSHQDAKREAAhptdvsisktalysrigtaevekpagllfqqpD 2767
Cdd:COG1196 212 AER-----YRELKEELK----ELEAELLLLKLRELEAELEELEAELE--------------------------------E 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2768 LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKsvshQTVQQLVLEKEQALADLN 2847
Cdd:COG1196 251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEELA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2848 SVEKSLADLfrrYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAH 2927
Cdd:COG1196 327 ELEEELEEL---EEELEELEEELEEAEEELEEAEAE-LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270
....*....|....*....|....*....|....*..
gi 1370456157 2928 QASLRKEQLRVDALERTLEQKNKEIEELTKICDELIA 2964
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2768-2966 |
4.52e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.54 E-value: 4.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2768 LDSALQIARAEIITKE-REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQmiedeqreksvshqtvqqlVLEKEQALADL 2846
Cdd:COG4717 47 LLERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEKEEEYAELQEE-------------------LEELEEELEEL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2847 NSVEKSLADLFRRYEKMKEVLEGFRKNEEvLKRCAQEYLSRVKKEEQRYQALKvHAEEKLDRANAEIAQVRGKAQQEQAA 2926
Cdd:COG4717 108 EAELEELREELEKLEKLLQLLPLYQELEA-LEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQ 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1370456157 2927 HQASLRKE-----------QLRVDALERTLEQKNKEIEELTKICDELIAKM 2966
Cdd:COG4717 186 LSLATEEElqdlaeeleelQQRLAELEEELEEAQEELEELEEELEQLENEL 236
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2696-2965 |
9.19e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 9.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2696 AQKLQEELEFAIMRIEALKLARQI---ALASRSHQDAKREAAHPTDVSISKTALYSRigTAEVEKPAGLLFQQPDLDSAL 2772
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAkkkADEAKKAAEAKKKADEAKKAEEAKKADEAK--KAEEAKKADEAKKAEEKKKAD 1549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2773 QIARAEIITKEREVSewkdKYEESRREvmEMRKIVAEYEKTIAQMIEdEQREKSVSHQTVQQLVLEKEQALADlnSVEKS 2852
Cdd:PTZ00121 1550 ELKKAEELKKAEEKK----KAEEAKKA--EEDKNMALRKAEEAKKAE-EARIEEVMKLYEEEKKMKAEEAKKA--EEAKI 1620
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2853 LADLFRRYEKMKEVLEGFRKNEEVLKRCAQEylsrVKKEEQRYqalKVHAEEKLDRANAEiaqvRGKAQQEQAAHQASLR 2932
Cdd:PTZ00121 1621 KAEELKKAEEEKKKVEQLKKKEAEEKKKAEE----LKKAEEEN---KIKAAEEAKKAEED----KKKAEEAKKAEEDEKK 1689
|
250 260 270
....*....|....*....|....*....|...
gi 1370456157 2933 KEQlrvdALERTLEQKNKeIEELTKICDELIAK 2965
Cdd:PTZ00121 1690 AAE----ALKKEAEEAKK-AEELKKKEAEEKKK 1717
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2707-2957 |
2.78e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.61 E-value: 2.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2707 IMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRIgtAEVEKpaglLFQQPDLDSALQIARAEiitKEREV 2786
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI--EEVMK----LYEEEKKMKAEEAKKAE---EAKIK 1621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2787 SEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQA--LADLNSVEKSLADLFRRYEKMK 2864
Cdd:PTZ00121 1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeeAKKAEEDEKKAAEALKKEAEEA 1701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2865 EVLEGFRKNEEVLKRCAQEYlsRVKKEEQRYQALKVHAEEKLDRANAEIAQVR-------GKAQQEQAAHQASLRKEQLR 2937
Cdd:PTZ00121 1702 KKAEELKKKEAEEKKKAEEL--KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDeeekkkiAHLKKEEEKKAEEIRKEKEA 1779
|
250 260
....*....|....*....|..
gi 1370456157 2938 V--DALERTLEQKNKEIEELTK 2957
Cdd:PTZ00121 1780 VieEELDEEDEKRRMEVDKKIK 1801
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2776-2955 |
2.80e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 2.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2776 RAEIITKEREVseWKDKYEESRREVMEMRKIVAEYEktiaQMIEDEQREKSVSHQTVQQLVL---EKEQALADLNSVEKS 2852
Cdd:TIGR02168 219 KAELRELELAL--LVLRLEELREELEELQEELKEAE----EELEELTAELQELEEKLEELRLevsELEEEIEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2853 LADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKaqqeqaahqasLR 2932
Cdd:TIGR02168 293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE-----------LE 361
|
170 180
....*....|....*....|...
gi 1370456157 2933 KEQLRVDALERTLEQKNKEIEEL 2955
Cdd:TIGR02168 362 ELEAELEELESRLEELEEQLETL 384
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2697-2965 |
3.19e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 3.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2697 QKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAhptdvsisKTALYSRigTAEVEkpagllfqqpDLDSALQIAR 2776
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAELEAELEEL--------RLELEEL--ELELE----------EAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2777 AEIITKEREVSEWKdkyEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVShQTVQQLVLEKEQALADLNSVEKSLADL 2856
Cdd:COG1196 295 AELARLEQDIARLE---ERRRELEERLEELEEELAELEEELEELEEELEELE-EELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2857 FRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG--KAQQEQAAHQASLRKE 2934
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEleEEEEEEEEALEEAAEE 450
|
250 260 270
....*....|....*....|....*....|.
gi 1370456157 2935 QLRVDALERTLEQKNKEIEELTKICDELIAK 2965
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAE 481
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2776-2965 |
3.79e-06 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 51.45 E-value: 3.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2776 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMiEDEQreksvshQTvQQLVLEKEQALadlnsVEKsLAD 2855
Cdd:COG1340 80 RDELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERL-EWRQ-------QT-EVLSPEEEKEL-----VEK-IKE 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2856 LFRRYEKMKEVLEGFRKNEEVLKRCAQEylsRVKKEEQRyQALKVHAEEkLDRANAEIAQVRGKAQqeqaahqaSLRKE- 2934
Cdd:COG1340 145 LEKELEKAKKALEKNEKLKELRAELKEL---RKEAEEIH-KKIKELAEE-AQELHEEMIELYKEAD--------ELRKEa 211
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456157 2935 ----------QLRVDALERTLEQKNKEIEELTKICDELIAK 2965
Cdd:COG1340 212 delhkeiveaQEKADELHEEIIELQKELRELRKELKKLRKK 252
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2696-2948 |
4.23e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.75 E-value: 4.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2696 AQKLQE--------ELEFAIMRIEALK-----LARQIALASRSHQDAKREAAHpTDVSISKT------------------ 2744
Cdd:TIGR02168 212 AERYKElkaelrelELALLVLRLEELReeleeLQEELKEAEEELEELTAELQE-LEEKLEELrlevseleeeieelqkel 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2745 -ALYSRIGTAEV------EKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM 2817
Cdd:TIGR02168 291 yALANEISRLEQqkqilrERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2818 iEDEQREKSVSHQTVQQLVLEKEQALADLNS----VEKSLADLFRRYEKMKEVLEGFRKN-EEVLKRCAQEYLSRVKKEE 2892
Cdd:TIGR02168 371 -ESRLEELEEQLETLRSKVAQLELQIASLNNeierLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEEL 449
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1370456157 2893 QRYQALKVHAEEKLDRANAEIAQVRgkaqQEQAAHQASLRKEQLRVDALERTLEQK 2948
Cdd:TIGR02168 450 EELQEELERLEEALEELREELEEAE----QALDAAERELAQLQARLDSLERLQENL 501
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2699-2917 |
6.07e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 6.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2699 LQEELEFAIMRIEALKlaRQIALASRSHQDAKREAAHpTDVSISKT-----ALYSRIGTAEVEKPAgllfqqpdLDSALQ 2773
Cdd:TIGR02169 292 VKEKIGELEAEIASLE--RSIAEKERELEDAEERLAK-LEAEIDKLlaeieELEREIEEERKRRDK--------LTEEYA 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2774 IARAEIITKEREVSEWKDKYEESRREVMEMRKivaEYEKTIAQMiEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSL 2853
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYRE---KLEKLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKI 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456157 2854 ADLfrrYEKMKEVLEGFRKNEEVLKRCAQEylsrVKKEEQRYQALKvhaeEKLDRANAEIAQVR 2917
Cdd:TIGR02169 437 NEL---EEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLK----EEYDRVEKELSKLQ 489
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2776-2957 |
6.29e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 6.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2776 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM---IEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKS 2852
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2853 LADLfrrYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLR 2932
Cdd:TIGR02168 756 LTEL---EAEIEELEERLEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831
|
170 180
....*....|....*....|....*...
gi 1370456157 2933 K---EQLRVDALERTLEQKNKEIEELTK 2957
Cdd:TIGR02168 832 RiaaTERRLEDLEEQIEELSEDIESLAA 859
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2775-2964 |
7.37e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.99 E-value: 7.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2775 ARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED-----EQREKSVSHQTVQQ---------LVLEKE 2840
Cdd:TIGR02169 154 ERRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQlerlrREREKAERYQALLKekreyegyeLLKEKE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2841 QALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKE-EQRYQALKvhaeEKLDRANAEIAQVRGK 2919
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVK----EKIGELEAEIASLERS 309
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1370456157 2920 AQQEQAAHQAS---LRKEQLRVDALERTLEQKNKEIEELTKICDELIA 2964
Cdd:TIGR02169 310 IAEKERELEDAeerLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2761-2963 |
1.05e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2761 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQ-------REKSVSHQTVQ 2833
Cdd:TIGR02169 228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlrvkekiGELEAEIASLE 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2834 QLVLEKEQALADLnsvEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEkLDRANAEi 2913
Cdd:TIGR02169 308 RSIAEKERELEDA---EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE-VDKEFAE- 382
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2914 aqvrgkaqqeqaahqasLRKEQlrvDALERTLEQKNKEIEELTKICDELI 2963
Cdd:TIGR02169 383 -----------------TRDEL---KDYREKLEKLKREINELKRELDRLQ 412
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
2764-2965 |
1.19e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 1.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2764 QQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIaqmiedEQREKSVSHQTVQQLVLEKEQAL 2843
Cdd:COG4942 49 EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL------EAQKEELAELLRALYRLGRQPPL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2844 ADLNSVEkSLADLFRRYEKMKEVLEGFRKNEEVLKRcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQE 2923
Cdd:COG4942 123 ALLLSPE-DFLDAVRRLQYLKYLAPARREQAEELRA-DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKL 200
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1370456157 2924 qaahqasLRKEQLRVDALERTLEQKNKEIEELTKICDELIAK 2965
Cdd:COG4942 201 -------LARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2754-2962 |
1.58e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.83 E-value: 1.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2754 EVEKPAGLLFQQPdldSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQ 2833
Cdd:PRK03918 311 EIEKRLSRLEEEI---NGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2834 QLVLE-------KEQALADLNSVEKSLADLFRRYEKMKEVLEGFRK------------NEEVLKRCAQEYLSRVKKEEQR 2894
Cdd:PRK03918 388 KLEKEleelekaKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKE 467
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370456157 2895 YQALKvHAEEKLDRANAEIAQVRGKAQQ--EQAAHQASLR--KEQLRVDALERtLEQKNKEIEELTKICDEL 2962
Cdd:PRK03918 468 LKEIE-EKERKLRKELRELEKVLKKESEliKLKELAEQLKelEEKLKKYNLEE-LEKKAEEYEKLKEKLIKL 537
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
107-688 |
2.73e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 50.32 E-value: 2.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 107 ARGPEGSLLPSPPPSQerehPSSSMPFAEC---PPEGCLASPAAAPEDGPQTQSPRrepapnAPGDIAAAFPAerdsstP 183
Cdd:PHA03247 2548 AGDPPPPLPPAAPPAA----PDRSVPPPRPaprPSEPAVTSRARRPDAPPQSARPR------APVDDRGDPRG------P 2611
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 184 YQEIAAVPSAGRERQPKEEGQKSSFSFSSGidqSPGMSPVPLRePMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGV 263
Cdd:PHA03247 2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPH---PPPTVPPPER-PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRA 2687
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 264 ASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAP-RASDRERGQGEAPPqyltddleflrachlPRSNSGAAPE 342
Cdd:PHA03247 2688 ARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAaRQASPALPAAPAPP---------------AVPAGPATPG 2752
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 343 AEVNAASQESCQQPVGAYLPHAelPWGLPSPALVPEAGGSGKEALDTIDVQGHPqtgmrgTKPNQVVCVAAGGQPEGGLP 422
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAA--PAAGPPRRLTRPAVASLSESRESLPSPWDP------ADPPAAVLAPAAALPPAASP 2824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 423 VSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDaglvglerqvsdlgskgehp 502
Cdd:PHA03247 2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVR-------------------- 2884
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 503 egdpgEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSP 582
Cdd:PHA03247 2885 -----RLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 583 AVAKEGSRSPGD---------SPGGKEEAPEPP-----DGGDPGNLQGEDSQAFSSKRDP-EVGKDELSKPSSDAESRDH 647
Cdd:PHA03247 2960 PQPWLGALVPGRvavprfrvpQPAPSREAPASStppltGHSLSRVSSWASSLALHEETDPpPVSLKQTLWPPDDTEDSDA 3039
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1370456157 648 PSSHSAQPPRKGGAG---HTDGPHSQTAEADASGLPHKLGEEDP 688
Cdd:PHA03247 3040 DSLFDSDSERSDLEAldpLPPEPHDPFAHEPDPATPEAGARESP 3083
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
2143-2530 |
2.93e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 50.07 E-value: 2.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2143 SGENLASETKTESAKTEGPSpalleETPLEPAVGPKAacPLDSESAEGVVPPASGggrvQNSPPVGRKtlPLTTapEAGE 2222
Cdd:PTZ00449 492 SKKKLAPIEEEDSDKHDEPP-----EGPEASGLPPKA--PGDKEGEEGEHEDSKE----SDEPKEGGK--PGET--KEGE 556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2223 VTPSDSGGQEDSPAK--GLSVRLEFDySEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPeKLDNTPASP--PR 2298
Cdd:PTZ00449 557 VGKKPGPAKEHKPSKipTLSKKPEFP-KDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIP-KSPKRPESPksPK 634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2299 SPAEPNDiPIAKgtytfdidkwDDPNFNPFSSTSKMQESPKLPqqsynFDPDTCDESVDPFktssktpsspskspasfei 2378
Cdd:PTZ00449 635 RPPPPQR-PSSP----------ERPEGPKIIKSPKPPKSPKPP-----FDPKFKEKFYDDY------------------- 679
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2379 pasameangvdgdgLNKPAKKKKTPLKTMVEDVMSVCSLFDTFRVKKSPKRSPLSDPPSQdPTPAATPETPPvisavvHA 2458
Cdd:PTZ00449 680 --------------LDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKL-PRDEEFPFEPI------GD 738
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370456157 2459 TDEEKlavtnqkwtcmtvdlEADKQDYPQPSDLSTFVNETKFSSPTEGKQLCSQLDPHSASENPAPREPKAR 2530
Cdd:PTZ00449 739 PDAEQ---------------PDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEAMKR 795
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2776-2962 |
2.96e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.68 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2776 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAE------YEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSV 2849
Cdd:PRK03918 458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKeselikLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKL 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2850 EKSLADLFRRYEKMKE-------VLEGFRKNEE----VLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEiaqvrg 2918
Cdd:PRK03918 538 KGEIKSLKKELEKLEElkkklaeLEKKLDELEEelaeLLKELEELGFESVEELEERLKELEPFYNEYLELKDAE------ 611
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1370456157 2919 kaqQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDEL 2962
Cdd:PRK03918 612 ---KELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEL 652
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2772-2913 |
4.26e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.29 E-value: 4.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2772 LQIARAEIITKEREVSEWKDKYEESRREVMEMRKI--VAEYEKtiaqmIEDEQREKSVSHQTVQQlvlEKEQALADLNSV 2849
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKysEEEYEE-----LREEYLELSRELAGLRA---ELEELEKRREEI 692
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370456157 2850 EKSLADLFRRYEKMKEVlegfRKNEEVLKRcAQEYLSRVKKEEQRYQAL-KVHAEEKLDRANAEI 2913
Cdd:PRK03918 693 KKTLEKLKEELEEREKA----KKELEKLEK-ALERVEELREKVKKYKALlKERALSKVGEIASEI 752
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2686-2889 |
4.51e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 4.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2686 DLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDvsiSKTALYSRIGTAEvEKPAGLLFQQ 2765
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE---ELQRLSEELADLN-AAIAGIEAKI 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2766 PDLDSALQIARAEIITKEREVSEWKDKYEESRRevmEMRKIVAEYEKtiaqmIEDEQREKS-----------VSHQTV-- 2832
Cdd:TIGR02169 437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ---ELYDLKEEYDR-----VEKELSKLQrelaeaeaqarASEERVrg 508
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370456157 2833 ---QQLVLEkeqalADLNSVEKSLADLFR---RYEKMKEVLEGFR------KNEEVLKRCAqEYLSRVK 2889
Cdd:TIGR02169 509 graVEEVLK-----ASIQGVHGTVAQLGSvgeRYATAIEVAAGNRlnnvvvEDDAVAKEAI-ELLKRRK 571
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2794-2957 |
4.67e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 48.36 E-value: 4.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2794 EESRREVMEMRKIVAEYEKTIAQmIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKN 2873
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREE-LEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2874 EEVLkrcaQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQvrgkaqqeqaahqaslRKEQLRvdALERTLEQKNKEIE 2953
Cdd:COG4372 110 AEEL----QEELEELQKERQDLEQQRKQLEAQIAELQSEIAE----------------REEELK--ELEEQLESLQEELA 167
|
....
gi 1370456157 2954 ELTK 2957
Cdd:COG4372 168 ALEQ 171
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
2697-2957 |
5.26e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 48.80 E-value: 5.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2697 QKLQEELEFAIMRIEALKLARQIALA--SRSHQDAKREaahpTDVSIsktalysRIGTAEVEKpagllfQQPDLDSALQI 2774
Cdd:COG5185 296 EKIAEYTKSIDIKKATESLEEQLAAAeaEQELEESKRE----TETGI-------QNLTAEIEQ------GQESLTENLEA 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2775 ARAEII---------TKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED---EQREKSVSHQT-VQQLVLEKEQ 2841
Cdd:COG5185 359 IKEEIEnivgevelsKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDtlkAADRQIEELQRqIEQATSSNEE 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2842 ALADLNSVEKSLADLFRR---------YEKMKEVLEGFRKNEEVLKRcaqeylsRVKKEEQRYQALKVHAEEKLDRANAE 2912
Cdd:COG5185 439 VSKLLNELISELNKVMREadeesqsrlEEAYDEINRSVRSKKEDLNE-------ELTQIESRVSTLKATLEKLRAKLERQ 511
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1370456157 2913 IAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 2957
Cdd:COG5185 512 LEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNA 556
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2776-2968 |
6.32e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.60 E-value: 6.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2776 RAEIITkerEVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE------DEQREKSVSHQTVQQLVLEKEQALADLNSV 2849
Cdd:COG1340 31 RDELNE---ELKELAEKRDELNAQVKELREEAQELREKRDELNEkvkelkEERDELNEKLNELREELDELRKELAELNKA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2850 EKSLADLFRRYEKMK-----EVLeGFRKNEEVLKRCAQ--EYLSRVKKEEQ----------RYQALKVHAE--------- 2903
Cdd:COG1340 108 GGSIDKLRKEIERLEwrqqtEVL-SPEEEKELVEKIKEleKELEKAKKALEkneklkelraELKELRKEAEeihkkikel 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370456157 2904 -EKLDRANAEIAQVRGKaqqeqaahQASLRKEqlrVDALERTLEQKNKEIEELTKICDELIAKMGK 2968
Cdd:COG1340 187 aEEAQELHEEMIELYKE--------ADELRKE---ADELHKEIVEAQEKADELHEEIIELQKELRE 241
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2762-2954 |
8.88e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.59 E-value: 8.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2762 LFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEyektIAQMIEDEQREKSVSHQTVQQLVLEKEQ 2841
Cdd:COG4372 37 LFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEE----LNEQLQAAQAELAQAQEELESLQEEAEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2842 ALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQAL-KVHAEEKLDRANAEIAQV---- 2916
Cdd:COG4372 113 LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALeQELQALSEAEAEQALDELlkea 192
|
170 180 190
....*....|....*....|....*....|....*....
gi 1370456157 2917 -RGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEE 2954
Cdd:COG4372 193 nRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKL 231
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2771-2955 |
9.07e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 9.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2771 ALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI----------------VAEYEKTIAQmIEDEQREKSVSHQTVQQ 2834
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERrealqrlaeyswdeidVASAEREIAE-LEAELERLDASSDDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2835 LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIA 2914
Cdd:COG4913 690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD-RLEAAEDLARLELRALLEERFAAALGDAVERELR 768
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456157 2915 QvrgkaqqeqaahqaSLRKeqlRVDALERTLEQKNKEIEEL 2955
Cdd:COG4913 769 E--------------NLEE---RIDALRARLNRAEEELERA 792
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2709-2965 |
1.58e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2709 RIEALKLARQialASRSHQDAKR--------EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEII 2780
Cdd:PTZ00121 1225 KAEAVKKAEE---AKKDAEEAKKaeeernneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2781 TKEREV---SEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALAD--LNSVEKSLAD 2855
Cdd:PTZ00121 1302 KKADEAkkkAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAekKKEEAKKKAD 1381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2856 LFRRYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEE--KLDRANAEIAQVR----GKAQQEQAAHQA 2929
Cdd:PTZ00121 1382 AAKKKAEEKKKADEAKKKAEEDKKKADE-LKKAAAAKKKADEAKKKAEEkkKADEAKKKAEEAKkadeAKKKAEEAKKAE 1460
|
250 260 270
....*....|....*....|....*....|....*....
gi 1370456157 2930 SLRK---EQLRVDALERTLEQKNKEiEELTKICDELIAK 2965
Cdd:PTZ00121 1461 EAKKkaeEAKKADEAKKKAEEAKKA-DEAKKKAEEAKKK 1498
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
93-495 |
1.64e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 1.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 93 VSPEVTEPRKDPQGARGPEGSLLPSP----PPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPG 168
Cdd:PRK07764 387 VAGGAGAPAAAAPSAAAAAPAAAPAPaaaaPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 169 DIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQS--PGMSPVPLREPMKAPLCGEGDQPGGFESQ 246
Cdd:PRK07764 467 APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERwpEILAAVPKRSRKTWAILLPEATVLGVRGD 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 247 E---KEAAGGFPPAESRQGVASV-----------QVTPEA-----PAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASD 307
Cdd:PRK07764 547 TlvlGFSTGGLARRFASPGNAEVlvtalaeelggDWQVEAvvgpaPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAA 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 308 RERGQGEAPPQYLTDDleflRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEAL 387
Cdd:PRK07764 627 PAPAGAAAAPAEASAA----PAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA 702
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 388 DTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSllTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSK 467
Cdd:PRK07764 703 PAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP--EPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
|
410 420
....*....|....*....|....*...
gi 1370456157 468 AGMPVSADAAKEVVDAGLVGLERQVSDL 495
Cdd:PRK07764 781 EEEEMAEDDAPSMDDEDRRDAEEVAMEL 808
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2773-2947 |
1.86e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2773 QIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQ-TVQQLVLEKEQALADLNSVEK 2851
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLlQLLPLYQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2852 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQE--------------YLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVR 2917
Cdd:COG4717 147 RLEELEERLEELRELEEELEELEAELAELQEEleelleqlslateeELQDLAEELEELQQRLAELEEELEEAQEELEELE 226
|
170 180 190
....*....|....*....|....*....|
gi 1370456157 2918 GKAQQEqaahqaslrKEQLRVDALERTLEQ 2947
Cdd:COG4717 227 EELEQL---------ENELEAAALEERLKE 247
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1526-1987 |
1.95e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 1.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 1526 ERNLPGAGVGKEMAGVPPTlredERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHG 1605
Cdd:PRK07764 382 ERRLGVAGGAGAPAAAAPS----AAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPP 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 1606 EEAVAQDR-IPSGKQHQETSACDSPHGEDGPGDFAHTGVPghvpRSTCAPSPQREVLTVPEAnsepWT--LDTLGGERRp 1682
Cdd:PRK07764 458 PAAAPSAQpAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAP----AAPAAPAGADDAATLRER----WPeiLAAVPKRSR- 528
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 1683 gVTAGILemrnalgnqsTPAPPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASgdlpEAGTTRTFSVVAGDlvl 1762
Cdd:PRK07764 529 -KTWAIL----------LPEATVLGVRGDTLVLGFSTGGLARRFASPGNAEVLVTALAE----ELGGDWQVEAVVGP--- 590
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 1763 pgscqDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGdgkvcvsSPPEPDET-HDPKLQHLAPEELHTDRE 1841
Cdd:PRK07764 591 -----APGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAG-------AAAAPAEAsAAPAPGVAAPEHHPKHVA 658
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 1842 SPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESISPAAAHAGlpPSAAEHIVSPSAPAG-DRVEASTPSCPDPAKD 1920
Cdd:PRK07764 659 VPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPA--PAATPPAGQADDPAAqPPQAAQGASAPSPAAD 736
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370456157 1921 LSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVE 1987
Cdd:PRK07764 737 DPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEE 803
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
258-622 |
4.18e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 4.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 258 ESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNS 337
Cdd:PRK07764 382 ERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 338 GAAPEAEVNAASQESCQQPVGAYLPHAElPWGLPSPALVPEAGGSGKEAlDTID-------------------------- 391
Cdd:PRK07764 462 PSAQPAPAPAAAPEPTAAPAPAPPAAPA-PAAAPAAPAAPAAPAGADDA-ATLRerwpeilaavpkrsrktwaillpeat 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 392 ---------VQGHPQTGMRG--TKPN-----------------QVVCVAAGGQPEGGLPVSPEP-SLLTPTEEAHPASSL 442
Cdd:PRK07764 540 vlgvrgdtlVLGFSTGGLARrfASPGnaevlvtalaeelggdwQVEAVVGPAPGAAGGEGPPAPaSSGPPEEAARPAAPA 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 443 ASF--PAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGeh 520
Cdd:PRK07764 620 APAapAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAA-- 697
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 521 lnteQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARG---------PPGPTDGAKVHEDSTSPAVAKEGSRS 591
Cdd:PRK07764 698 ----PAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPvplppepddPPDPAGAPAQPPPPPAPAPAAAPAAA 773
|
410 420 430
....*....|....*....|....*....|.
gi 1370456157 592 PGDSPGGKEEAPEPPDGGDPGNLQGEDSQAF 622
Cdd:PRK07764 774 PPPSPPSEEEEMAEDDAPSMDDEDRRDAEEV 804
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
2773-2965 |
5.26e-04 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 44.91 E-value: 5.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2773 QIARAEIITKEREvsewkdkyEESRREVMEMRKivaEYEKTIAQMIEDEQREKSVSHQTVQQLV-----------LEKEQ 2841
Cdd:pfam13868 27 QIAEKKRIKAEEK--------EEERRLDEMMEE---ERERALEEEEEKEEERKEERKRYRQELEeqieereqkrqEEYEE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2842 ALADLNSV--------EKSLADLFRRYEKMKEVLEGFRK-NEEVLKRCAQEYLsRVKKEEQRYQAlkvHAEEKLDRANAE 2912
Cdd:pfam13868 96 KLQEREQMdeiveriqEEDQAEAEEKLEKQRQLREEIDEfNEEQAEWKELEKE-EEREEDERILE---YLKEKAEREEER 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456157 2913 IAQVRGKAqqeqaahqaslRKEQLRVDALERTLEQKNKEIEELtkicDELIAK 2965
Cdd:pfam13868 172 EAEREEIE-----------EEKEREIARLRAQQEKAQDEKAER----DELRAK 209
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
24-319 |
9.23e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.16 E-value: 9.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 24 PPNPEPTQRTLSAQTPRSAQPPGNSQNIKrkqqdTPGSPDHRDASSIGSVGLGGFCTASESSASLDP----CLVSPEVTE 99
Cdd:PHA03307 67 PPTGPPPGPGTEAPANESRSTPTWSLSTL-----APASPAREGSPTPPGPSSPDPPPPTPPPASPPPspapDLSEMLRPV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 100 PRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERD 179
Cdd:PHA03307 142 GSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 180 SSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAES 259
Cdd:PHA03307 222 PAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPS 301
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370456157 260 RQGV--------ASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPI--------PQDPAPRASDRERGQGEAPPQY 319
Cdd:PHA03307 302 SPGSgpapssprASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPsrspspsrPPPPADPSSPRKRPRPSRAPSS 377
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
241-715 |
9.88e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.16 E-value: 9.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 241 GGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAqqgtesSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPP--- 317
Cdd:PHA03307 17 GGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAA------VTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTptw 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 318 QYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGkealdtidvqghpq 397
Cdd:PHA03307 91 SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAG-------------- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 398 tgmrgtkpnqvvcvAAGGQPEGGLPVSPEPSLLTPTEEAH---PASSLASFPAAQIPIAVEEPGSS-SRESVSKAGMPVS 473
Cdd:PHA03307 157 --------------ASPAAVASDAASSRQAALPLSSPEETaraPSSPPAEPPPSTPPAAASPRPPRrSSPISASASSPAP 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 474 ADAAKEVVDAG-----LVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQShevqpgvpppplpkEQSHEVQP 548
Cdd:PHA03307 223 APGRSAADDAGasssdSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSS--------------RPGPASSS 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 549 GAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDP 628
Cdd:PHA03307 289 SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 629 EvgkdelskPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIW 708
Cdd:PHA03307 369 P--------RPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPSGEPW 440
|
....*..
gi 1370456157 709 EGSGLQP 715
Cdd:PHA03307 441 PGSPPPP 447
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2775-2908 |
9.98e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 44.13 E-value: 9.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2775 ARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTI----AQMIE-----DEQREKSVS-HQTVQqlvlEKEQALA 2844
Cdd:COG1340 151 KAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAqelhEEMIElykeaDELRKEADElHKEIV----EAQEKAD 226
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456157 2845 DLNsveKSLADLFRRYEKMKEVLEGFRKNEEVLKRcaqeylsrvKKEEQRYQALKVHAEEKLDR 2908
Cdd:COG1340 227 ELH---EEIIELQKELRELRKELKKLRKKQRALKR---------EKEKEELEEKAEEIFEKLKK 278
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2690-2882 |
2.11e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2690 KNPPLFAQKLqEELEfaimriEALKLARQIALASRSHQDAKREA-AHPTDVSISKTALYSRIGTAEVEKPAGLLFQQpdl 2768
Cdd:COG4717 64 RKPELNLKEL-KELE------EELKEAEEKEEEYAELQEELEELeEELEELEAELEELREELEKLEKLLQLLPLYQE--- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2769 dsaLQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNS 2848
Cdd:COG4717 134 ---LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAE 210
|
170 180 190
....*....|....*....|....*....|....
gi 1370456157 2849 VEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQ 2882
Cdd:COG4717 211 LEEELEEAQEELEELEEELEQLENELEAAALEER 244
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
2775-2954 |
2.29e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 42.98 E-value: 2.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2775 ARAEIITKEREVSEWKDKYEEsrREVMEMRKIvAEYEKTIAQ---MIEDEQREKSVSHQTVQQLVL-----------EKE 2840
Cdd:pfam13868 128 LREEIDEFNEEQAEWKELEKE--EEREEDERI-LEYLKEKAEreeEREAEREEIEEEKEREIARLRaqqekaqdekaERD 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2841 QALADLNSVE-------KSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYlsRVKKEEQRYQALKVHAE-EKLDRANAE 2912
Cdd:pfam13868 205 ELRAKLYQEEqerkerqKEREEAEKKARQRQELQQAREEQIELKERRLAEE--AEREEEEFERMLRKQAEdEEIEQEEAE 282
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1370456157 2913 iaQVRGKAQQEQAAHQASLR-KEQLRVDALERTLEQKNKEIEE 2954
Cdd:pfam13868 283 --KRRMKRLEHRRELEKQIEeREEQRAAEREEELEEGERLREE 323
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2792-2968 |
2.39e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 2.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2792 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEgfR 2871
Cdd:COG4372 7 KVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELE--E 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2872 KNEEVLKrcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRgkaqqeqaahqasLRKEQL--RVDALERTLEQKN 2949
Cdd:COG4372 85 LNEQLQA--AQAELAQAQEELESLQEEAEELQEELEELQKERQDLE-------------QQRKQLeaQIAELQSEIAERE 149
|
170
....*....|....*....
gi 1370456157 2950 KEIEELTKICDELIAKMGK 2968
Cdd:COG4372 150 EELKELEEQLESLQEELAA 168
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
2770-2957 |
2.45e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.47 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2770 SALQIARAEIITKE--REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM-------------IEDEQREKsvsHQTVQQ 2834
Cdd:TIGR04523 298 SDLNNQKEQDWNKElkSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLkkeltnsesenseKQRELEEK---QNEIEK 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2835 LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKrcaQEYLSrVKKEEQRYQALKVHAEEKLDRANAEIA 2914
Cdd:TIGR04523 375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ---QEKEL-LEKEIERLKETIIKNNSEIKDLTNQDS 450
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456157 2915 ----------QVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 2957
Cdd:TIGR04523 451 vkeliiknldNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNE 503
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
2573-2954 |
2.71e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.19 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2573 DTSQESPVKSSPVRM-SESPTPCS-GSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQvpeKSSQKELEAMGLGTPSEA 2650
Cdd:pfam17380 181 RRRGNHSAFTRPGRPrTTTPMPVThATRFVPGIQMSTVAPKEVQGMPHTLAPYEKMERR---KESFNLAEDVTTMTPEYT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2651 IEITapeGSFASADALLSRLAHPVSLCGALDylEPDLAEKNPPLFAQKLQEELEFAIMRIEAlklARQIALASRSHQDA- 2729
Cdd:pfam17380 258 VRYN---GQTMTENEFLNQLLHIVQHQKAVS--ERQQQEKFEKMEQERLRQEKEEKAREVER---RRKLEEAEKARQAEm 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2730 KREA---AHPTDVSISKTALYSRIGTAEVEKPAGLLFQQpdlDSALQIARAEIItkEREVSEWKDKYEESRREVMEMRKi 2806
Cdd:pfam17380 330 DRQAaiyAEQERMAMERERELERIRQEERKRELERIRQE---EIAMEISRMREL--ERLQMERQQKNERVRQELEAARK- 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2807 vaeyektiaQMIEDEQREKSVSHQTVQQLVLEKEQaladlnsvEKSLADLFRRYEKMKEvLEGFRKNEEVLKRCAQEYLS 2886
Cdd:pfam17380 404 ---------VKILEEERQRKIQQQKVEMEQIRAEQ--------EEARQREVRRLEEERA-REMERVRLEEQERQQQVERL 465
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370456157 2887 RVKKEEQRYQALKVHAEEKlDRANAEiAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEE 2954
Cdd:pfam17380 466 RQQEEERKRKKLELEKEKR-DRKRAE-EQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE 531
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2776-2961 |
3.15e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.42 E-value: 3.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2776 RAEIITKEREVsewkdkyEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTV--QQLVLEKEQALADLNSVEKSL 2853
Cdd:pfam02463 185 LAELIIDLEEL-------KLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLneERIDLLQELLRDEQEEIESSK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2854 ADLFRRYEKMKEVLEGFRKNEEVLK-----------RCAQEYLSRVKKEEQRYQALK--VHAEEKLDRANAEIAQVRGKA 2920
Cdd:pfam02463 258 QEIEKEEEKLAQVLKENKEEEKEKKlqeeelkllakEEEELKSELLKLERRKVDDEEklKESEKEKKKAEKELKKEKEEI 337
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1370456157 2921 QQEQAAHQASLRKEQL----RVDALERTLEQKNKEIEELTKICDE 2961
Cdd:pfam02463 338 EELEKELKELEIKREAeeeeEEELEKLQEKLEQLEEELLAKKKLE 382
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
89-306 |
3.40e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 3.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 89 DPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAA-PEDGPQTQSPRREPAPNAP 167
Cdd:PHA03307 52 AVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPsSPDPPPPTPPPASPPPSPA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 168 GDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLRE--PMKAPLCGEGDQPGGFES 245
Cdd:PHA03307 132 PDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAepPPSTPPAAASPRPPRRSS 211
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370456157 246 QEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRAS 306
Cdd:PHA03307 212 PISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEA 272
|
|
| YqiK |
COG2268 |
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]; |
2748-2919 |
4.56e-03 |
|
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 42.17 E-value: 4.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2748 SRIGTAEVEKpagllfqqpdlDSALQIARAEiitKEREVSEwkdkyEESRREVMEMRkiVAEYEKTIAQMIEDEQREKsv 2827
Cdd:COG2268 201 ARIAEAEAER-----------ETEIAIAQAN---REAEEAE-----LEQEREIETAR--IAEAEAELAKKKAEERREA-- 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2828 shqtvqqlvlEKEQALADLnSVEKsladlfRRYEKMKEV---LEGFRKNEEVLkrcAQEylSRVKKEEQRYQA---LKVH 2901
Cdd:COG2268 258 ----------ETARAEAEA-AYEI------AEANAEREVqrqLEIAEREREIE---LQE--KEAEREEAELEAdvrKPAE 315
|
170 180
....*....|....*....|..
gi 1370456157 2902 AE----EKLDRANAEIAQVRGK 2919
Cdd:COG2268 316 AEkqaaEAEAEAEAEAIRAKGL 337
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2832-2956 |
5.32e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 5.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2832 VQQLVLEKEQALADLNsvekSLADLFRRYEKMKEVLEGFRKNEEVLKRC---AQEYLS-RVKKEEQRYQALKVH---AEE 2904
Cdd:COG4913 213 VREYMLEEPDTFEAAD----ALVEHFDDLERAHEALEDAREQIELLEPIrelAERYAAaRERLAELEYLRAALRlwfAQR 288
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1370456157 2905 KLDRANAEIAQVRgkaqqeqaahqASLRKEQLRVDALERTLEQKNKEIEELT 2956
Cdd:COG4913 289 RLELLEAELEELR-----------AELARLEAELERLEARLDALREELDELE 329
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
2768-2962 |
5.56e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 5.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2768 LDSALQIARAEIitkeREVSEW-KDKYEESRREVMEMRKIVAEYEKtiAQMIEDEQREKSVSHQTVQQLVLEKEQALADL 2846
Cdd:COG3206 162 LEQNLELRREEA----RKALEFlEEQLPELRKELEEAEAALEEFRQ--KNGLVDLSEEAKLLLQQLSELESQLAEARAEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2847 NSVEKSLADLFRRYEKMKEVLEGFRKNEEVlkrcaQEYLSRVKKEEQRYQALKVHAEEK---LDRANAEIAQVRGKAQQE 2923
Cdd:COG3206 236 AEAEARLAALRAQLGSGPDALPELLQSPVI-----QQLRAQLAELEAELAELSARYTPNhpdVIALRAQIAALRAQLQQE 310
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1370456157 2924 QAAHQASLRKE----QLRVDALERTLEQKNKEIEELTKICDEL 2962
Cdd:COG3206 311 AQRILASLEAElealQAREASLQAQLAQLEARLAELPELEAEL 353
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
2767-2966 |
5.70e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 5.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2767 DLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEyektiaqmIEDEQREKSVSHQTVQQLVLEKEQALA-- 2844
Cdd:COG1579 14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELED--------LEKEIKRLELEIEEVEARIKKYEEQLGnv 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2845 ----DLNSVEKSLADLfrryEKMKEVLEgfrknEEVLkrcaqeylsrvkkeeqryqalkvHAEEKLDRANAEIAQVRGKA 2920
Cdd:COG1579 86 rnnkEYEALQKEIESL----KRRISDLE-----DEIL-----------------------ELMERIEELEEELAELEAEL 133
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1370456157 2921 QQeqaahqaslRKEQLR--VDALERTLEQKNKEIEELTKICDELIAKM 2966
Cdd:COG1579 134 AE---------LEAELEekKAELDEELAELEAELEELEAEREELAAKI 172
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
2754-2963 |
7.52e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 41.75 E-value: 7.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2754 EVEKpagllfQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQR--EKSVSHQT 2831
Cdd:PRK04778 307 YVEK------NSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERiaEQEIAYSE 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2832 VQqlvlekeqalADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLS-------RVKKEE-----QRYQALK 2899
Cdd:PRK04778 381 LQ----------EELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNklheikrYLEKSNlpglpEDYLEMF 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456157 2900 VHAEEKLDRANAEIAQVRgkaqqeqaahqaslrkeqLRVDALERTLEQKNKEIEELTKICDELI 2963
Cdd:PRK04778 451 FEVSDEIEALAEELEEKP------------------INMEAVNRLLEEATEDVETLEEETEELV 496
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
2764-2967 |
7.95e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.95 E-value: 7.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2764 QQPDLDSalQIARAEIITK-EREVSEWKDKYEESRREVMEMRKIVAEYEKTI------AQMIEDEQREKSVSHQTVQQLV 2836
Cdd:PRK02224 490 EVEEVEE--RLERAEDLVEaEDRIERLEERREDLEELIAERRETIEEKRERAeelrerAAELEAEAEEKREAAAEAEEEA 567
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2837 LEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKvhaeEKLDRanaeIAQV 2916
Cdd:PRK02224 568 EEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA----EKRER----KREL 639
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456157 2917 RGKAQQEqaahqaslRKEQLRVDA--LERTLEQKNKEIEELTKICDELIAKMG 2967
Cdd:PRK02224 640 EAEFDEA--------RIEEAREDKerAEEYLEQVEEKLDELREERDDLQAEIG 684
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
2780-2968 |
8.82e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.88 E-value: 8.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2780 ITKEREVSEWKDKYE----ESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQT-VQQLVLEKEQALADLNSVEKSLA 2854
Cdd:TIGR00618 245 LTQKREAQEEQLKKQqllkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKaVTQIEQQAQRIHTELQSKMRSRA 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 2855 DLFRRY----------EKMKEVLEGFRKNEEVLKRCAQ------EYLSRVKKEEQRYQAL---KVHAEEKLDRANAEIAQ 2915
Cdd:TIGR00618 325 KLLMKRaahvkqqssiEEQRRLLQTLHSQEIHIRDAHEvatsirEISCQQHTLTQHIHTLqqqKTTLTQKLQSLCKELDI 404
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1370456157 2916 VRgKAQQEQAAHQASLRKEQLRVDALERT--LEQKNKEIEELTKICDELIAKMGK 2968
Cdd:TIGR00618 405 LQ-REQATIDTRTSAFRDLQGQLAHAKKQqeLQQRYAELCAAAITCTAQCEKLEK 458
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
162-390 |
9.47e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 9.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 162 PAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPG 241
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGW 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 242 GFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAvlekSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLT 321
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG----QADDPAAQPPQAAQGASAPSPAADDPVPLPPEP 745
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456157 322 DDLEFLRACHL-PRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPAlvpEAGGSGKEALDTI 390
Cdd:PRK07764 746 DDPPDPAGAPAqPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR---DAEEVAMELLEEE 812
|
|
| |
