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Conserved domains on  [gi|1370457304|ref|XP_024303821|]
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outer dynein arm-docking complex subunit 2 isoform X2 [Homo sapiens]

Protein Classification

armadillo/beta-catenin-like repeat-containing protein( domain architecture ID 13633099)

armadillo/beta-catenin-like repeat-containing protein similar to Saccharomyces cerevisiae vacuolar protein 8 that functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
897-1075 1.87e-09

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 56.95  E-value: 1.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  897 VKASAAWALCpcIKNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANT 976
Cdd:COG1413      1 VRRAAARALG--RLGDPAA----------VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKD 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  977 NNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMV 1056
Cdd:COG1413     59 PDPEVRAAAAEALGR----------IGDPEAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEAL 118
                          170
                   ....*....|....*....
gi 1370457304 1057 GSPDQDLQEAAAGCISNIR 1075
Cdd:COG1413    119 KDPDWEVRRAAARALGRLG 137
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
657-1085 6.05e-07

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 53.36  E-value: 6.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  657 QECASEENYRAAIKAERIIENLVKNLNSENEQLQeHCAMAIYQCAEDKETR---DLVRLHGGLKPLASLLNNTDNKERLA 733
Cdd:COG5064     55 SEEAESSFIPMEQQFYSELPQLTQQLFSDDIEQQ-LQAVYKFRKLLSKETSppiQPVIDAGVVPRFVEFMDEIQRDMLQF 133
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  734 AVTGAIWKCSISKENVTKFR-EYKAIETLVGLLTDQPEEVLVNVVGALGECCQEREN-RVIVRKCGGIQPLVNLLV--GI 809
Cdd:COG5064    134 EAAWALTNIASGTTQQTKVVvDAGAVPLFIQLLSSTEDDVREQAVWALGNIAGDSEGcRDYVLQCGALEPLLGLLLssAI 213
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  810 NQALLVNVTkavgacavepesmmWGLtlssrlkySGMMRGhcslkllgSSDPPNFVFFRSrklrnriidrldGVRLLWSL 889
Cdd:COG5064    214 HISMLRNAT--------------WTL--------SNLCRG--------KNPPPDWSNISQ------------ALPILAKL 251
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  890 LKNPHPDVKASAAWALC-------PCIKNAKDAGEMVRsfvgglelIVNLLKSDNKEVLASVCAAITNIAK-DQENLAVI 961
Cdd:COG5064    252 IYSRDPEVLVDACWAISylsdgpnEKIQAVLDVGIPGR--------LVELLSHESAKIQTPALRSVGNIVTgSDDQTQVI 323
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  962 TDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRV-AFGEHKAVAPLVRYLKSNDTNVHR----ATAQALYQLSED 1036
Cdd:COG5064    324 INCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIqAVIDANLIPPLIHLLSSAEYKIKKeacwAISNATSGGLNR 403
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1370457304 1037 ADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATEKAR 1085
Cdd:COG5064    404 PDIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDRLRY 452
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
624-661 6.55e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


:

Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.20  E-value: 6.55e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1370457304  624 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 661
Cdd:pfam00514    4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 super family cl33659
cellulose synthase-interactive protein; Provisional
449-684 9.73e-04

cellulose synthase-interactive protein; Provisional


The actual alignment was detected with superfamily member PLN03200:

Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 9.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200  1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200  1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200  1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861
                          250       260
                   ....*....|....*....|....*.
gi 1370457304  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200  1862 altAALEKDlwstaTVNEEVLRALNV 1887
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
897-1075 1.87e-09

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 56.95  E-value: 1.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  897 VKASAAWALCpcIKNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANT 976
Cdd:COG1413      1 VRRAAARALG--RLGDPAA----------VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKD 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  977 NNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMV 1056
Cdd:COG1413     59 PDPEVRAAAAEALGR----------IGDPEAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEAL 118
                          170
                   ....*....|....*....
gi 1370457304 1057 GSPDQDLQEAAAGCISNIR 1075
Cdd:COG1413    119 KDPDWEVRRAAARALGRLG 137
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
657-1085 6.05e-07

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 53.36  E-value: 6.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  657 QECASEENYRAAIKAERIIENLVKNLNSENEQLQeHCAMAIYQCAEDKETR---DLVRLHGGLKPLASLLNNTDNKERLA 733
Cdd:COG5064     55 SEEAESSFIPMEQQFYSELPQLTQQLFSDDIEQQ-LQAVYKFRKLLSKETSppiQPVIDAGVVPRFVEFMDEIQRDMLQF 133
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  734 AVTGAIWKCSISKENVTKFR-EYKAIETLVGLLTDQPEEVLVNVVGALGECCQEREN-RVIVRKCGGIQPLVNLLV--GI 809
Cdd:COG5064    134 EAAWALTNIASGTTQQTKVVvDAGAVPLFIQLLSSTEDDVREQAVWALGNIAGDSEGcRDYVLQCGALEPLLGLLLssAI 213
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  810 NQALLVNVTkavgacavepesmmWGLtlssrlkySGMMRGhcslkllgSSDPPNFVFFRSrklrnriidrldGVRLLWSL 889
Cdd:COG5064    214 HISMLRNAT--------------WTL--------SNLCRG--------KNPPPDWSNISQ------------ALPILAKL 251
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  890 LKNPHPDVKASAAWALC-------PCIKNAKDAGEMVRsfvgglelIVNLLKSDNKEVLASVCAAITNIAK-DQENLAVI 961
Cdd:COG5064    252 IYSRDPEVLVDACWAISylsdgpnEKIQAVLDVGIPGR--------LVELLSHESAKIQTPALRSVGNIVTgSDDQTQVI 323
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  962 TDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRV-AFGEHKAVAPLVRYLKSNDTNVHR----ATAQALYQLSED 1036
Cdd:COG5064    324 INCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIqAVIDANLIPPLIHLLSSAEYKIKKeacwAISNATSGGLNR 403
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1370457304 1037 ADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATEKAR 1085
Cdd:COG5064    404 PDIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDRLRY 452
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
885-990 2.29e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 41.17  E-value: 2.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  885 LLWSLLKNPHPDVKASAAWALCPCikNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDH 964
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI--GDPEA----------VPALLELLKDEDPAVRRAAAEA----------LGKIGDP 61
                           90       100
                   ....*....|....*....|....*..
gi 1370457304  965 GVVPLLSKLANTNNNK-LRHHLAEAIS 990
Cdd:pfam13646   62 EALPALLELLRDDDDDvVRAAAAEALA 88
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
624-661 6.55e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.20  E-value: 6.55e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1370457304  624 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 661
Cdd:pfam00514    4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
449-684 9.73e-04

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 9.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200  1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200  1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200  1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861
                          250       260
                   ....*....|....*....|....*.
gi 1370457304  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200  1862 altAALEKDlwstaTVNEEVLRALNV 1887
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
524-563 1.95e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.05  E-value: 1.95e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1370457304  524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA 563
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
621-656 2.42e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 36.64  E-value: 2.42e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1370457304   621 SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
625-823 2.70e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 42.01  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  625 KEAIRKAGGIPLLARLLKT----SHENMLIpVVGTLqeCASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQC 700
Cdd:PLN03200   481 KWAITAAGGIPPLVQLLETgsqkAKEDSAT-VLWNL--CCHSEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKL 557
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  701 AEDKETRDLVRLhgglkpLASLLNNT-DNKERLAAVTGAIWkCSISKENVtkFRE----YKAIETLVGLLTDQPEEVLVN 775
Cdd:PLN03200   558 VRTADAATISQL------TALLLGDLpESKVHVLDVLGHVL-SVASLEDL--VREgsaaNDALRTLIQLLSSSKEETQEK 628
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370457304  776 VVGALGECCQERENrvivrKCGG------IQPLVNLLVGINQALLVNVTKAVGA 823
Cdd:PLN03200   629 AASVLADIFSSRQD-----LCESlatdeiINPCIKLLTNNTEAVATQSARALAA 677
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
924-953 8.38e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.10  E-value: 8.38e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 1370457304   924 GGLELIVNLLKSDNKEVLASVCAAITNIAK 953
Cdd:smart00185   12 GGLPALVELLKSEDEEVVKEAAWALSNLSS 41
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
897-1075 1.87e-09

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 56.95  E-value: 1.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  897 VKASAAWALCpcIKNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANT 976
Cdd:COG1413      1 VRRAAARALG--RLGDPAA----------VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKD 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  977 NNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMV 1056
Cdd:COG1413     59 PDPEVRAAAAEALGR----------IGDPEAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEAL 118
                          170
                   ....*....|....*....
gi 1370457304 1057 GSPDQDLQEAAAGCISNIR 1075
Cdd:COG1413    119 KDPDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
883-1033 1.03e-07

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 51.94  E-value: 1.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  883 VRLLWSLLKNPHPDVKASAAWALcpciknakdaGEMVRSfvGGLELIVNLLKSDNKEVLASVCAAITNIAKDQenlavit 962
Cdd:COG1413     18 VPALIAALADEDPDVRAAAARAL----------GRLGDP--RAVPALLEALKDPDPEVRAAAAEALGRIGDPE------- 78
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370457304  963 dhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQL 1033
Cdd:COG1413     79 ---AVPALIAALKDEDPEVRRAAAEALGR----------LGDPAAVPALLEALKDPDWEVRRAAARALGRL 136
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
657-1085 6.05e-07

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 53.36  E-value: 6.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  657 QECASEENYRAAIKAERIIENLVKNLNSENEQLQeHCAMAIYQCAEDKETR---DLVRLHGGLKPLASLLNNTDNKERLA 733
Cdd:COG5064     55 SEEAESSFIPMEQQFYSELPQLTQQLFSDDIEQQ-LQAVYKFRKLLSKETSppiQPVIDAGVVPRFVEFMDEIQRDMLQF 133
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  734 AVTGAIWKCSISKENVTKFR-EYKAIETLVGLLTDQPEEVLVNVVGALGECCQEREN-RVIVRKCGGIQPLVNLLV--GI 809
Cdd:COG5064    134 EAAWALTNIASGTTQQTKVVvDAGAVPLFIQLLSSTEDDVREQAVWALGNIAGDSEGcRDYVLQCGALEPLLGLLLssAI 213
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  810 NQALLVNVTkavgacavepesmmWGLtlssrlkySGMMRGhcslkllgSSDPPNFVFFRSrklrnriidrldGVRLLWSL 889
Cdd:COG5064    214 HISMLRNAT--------------WTL--------SNLCRG--------KNPPPDWSNISQ------------ALPILAKL 251
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  890 LKNPHPDVKASAAWALC-------PCIKNAKDAGEMVRsfvgglelIVNLLKSDNKEVLASVCAAITNIAK-DQENLAVI 961
Cdd:COG5064    252 IYSRDPEVLVDACWAISylsdgpnEKIQAVLDVGIPGR--------LVELLSHESAKIQTPALRSVGNIVTgSDDQTQVI 323
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  962 TDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRV-AFGEHKAVAPLVRYLKSNDTNVHR----ATAQALYQLSED 1036
Cdd:COG5064    324 INCGALKAFRSLLSSPKENIRKEACWTISNITAGNTEQIqAVIDANLIPPLIHLLSSAEYKIKKeacwAISNATSGGLNR 403
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1370457304 1037 ADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATEKAR 1085
Cdd:COG5064    404 PDIIRYLVSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDRLRY 452
HEAT COG1413
HEAT repeat [General function prediction only];
627-782 6.82e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.93  E-value: 6.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  627 AIRKAGGIPLLARLLKTSHENMLIPVVGTLqecaseenyrAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKet 706
Cdd:COG1413     11 RLGDPAAVPALIAALADEDPDVRAAAARAL----------GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPE-- 78
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370457304  707 rdlvrlhgGLKPLASLLNNTDNKERLAAVTGaiwkcsiskenVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGE 782
Cdd:COG1413     79 --------AVPALIAALKDEDPEVRRAAAEA-----------LGRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
885-990 2.29e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 41.17  E-value: 2.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  885 LLWSLLKNPHPDVKASAAWALCPCikNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDH 964
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI--GDPEA----------VPALLELLKDEDPAVRRAAAEA----------LGKIGDP 61
                           90       100
                   ....*....|....*....|....*..
gi 1370457304  965 GVVPLLSKLANTNNNK-LRHHLAEAIS 990
Cdd:pfam13646   62 EALPALLELLRDDDDDvVRAAAAEALA 88
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
624-661 6.55e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.20  E-value: 6.55e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1370457304  624 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 661
Cdd:pfam00514    4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
449-684 9.73e-04

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 9.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200  1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200  1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200  1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861
                          250       260
                   ....*....|....*....|....*.
gi 1370457304  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200  1862 altAALEKDlwstaTVNEEVLRALNV 1887
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
966-1068 1.03e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 39.24  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  966 VVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhe 1045
Cdd:pfam13646    1 LPALLQALLRDPDPEVRAAAIRALGR----------IGDPEAVPALLELLKDEDPAVRRAAAEALGKIGDPE-------- 62
                           90       100
                   ....*....|....*....|....
gi 1370457304 1046 ngAVKLLLDMVGS-PDQDLQEAAA 1068
Cdd:pfam13646   63 --ALPALLELLRDdDDDVVRAAAA 84
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
1045-1074 1.09e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.82  E-value: 1.09e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 1370457304 1045 ENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1074
Cdd:pfam00514   10 EAGAVPPLVRLLSSPDEEVQEEAAWALSNL 39
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
524-563 1.95e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.05  E-value: 1.95e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1370457304  524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA 563
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
621-656 2.42e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 36.64  E-value: 2.42e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1370457304   621 SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
928-1030 2.51e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.09  E-value: 2.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  928 LIVNLLKSDNKEVLASVCAAITNIaKDQEnlavitdhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKA 1007
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI-GDPE---------AVPALLELLKDEDPAVRRAAAEALGK----------IGDPEA 63
                           90       100
                   ....*....|....*....|....
gi 1370457304 1008 VAPLVRYLKS-NDTNVHRATAQAL 1030
Cdd:pfam13646   64 LPALLELLRDdDDDVVRAAAAEAL 87
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
625-823 2.70e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 42.01  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  625 KEAIRKAGGIPLLARLLKT----SHENMLIpVVGTLqeCASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQC 700
Cdd:PLN03200   481 KWAITAAGGIPPLVQLLETgsqkAKEDSAT-VLWNL--CCHSEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKL 557
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  701 AEDKETRDLVRLhgglkpLASLLNNT-DNKERLAAVTGAIWkCSISKENVtkFRE----YKAIETLVGLLTDQPEEVLVN 775
Cdd:PLN03200   558 VRTADAATISQL------TALLLGDLpESKVHVLDVLGHVL-SVASLEDL--VREgsaaNDALRTLIQLLSSSKEETQEK 628
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370457304  776 VVGALGECCQERENrvivrKCGG------IQPLVNLLVGINQALLVNVTKAVGA 823
Cdd:PLN03200   629 AASVLADIFSSRQD-----LCESlatdeiINPCIKLLTNNTEAVATQSARALAA 677
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
924-953 8.38e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.10  E-value: 8.38e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 1370457304   924 GGLELIVNLLKSDNKEVLASVCAAITNIAK 953
Cdd:smart00185   12 GGLPALVELLKSEDEEVVKEAAWALSNLSS 41
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
875-1086 9.30e-03

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 39.87  E-value: 9.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  875 RIIDRLDGVRLLWSLLKNPHPDVKASAAWALcpciKNAKDAGEMVRSFV---GGLELIVNLLKSDNKEV---------LA 942
Cdd:COG5064    151 KVVVDAGAVPLFIQLLSSTEDDVREQAVWAL----GNIAGDSEGCRDYVlqcGALEPLLGLLLSSAIHIsmlrnatwtLS 226
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457304  943 SVCAAiTNIAKDQENLAVitdhgVVPLLSKLANTNNnklrhhlAEAISRCCmWGRNRVAFGEHKAVAP---------LVR 1013
Cdd:COG5064    227 NLCRG-KNPPPDWSNISQ-----ALPILAKLIYSRD-------PEVLVDAC-WAISYLSDGPNEKIQAvldvgipgrLVE 292
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370457304 1014 YLKSNDTNVHRATAQALYQLSEDADNCITMHEN-GAVKLLLDMVGSPDQDLQEAAAGCISNIRrlALATEKARY 1086
Cdd:COG5064    293 LLSHESAKIQTPALRSVGNIVTGSDDQTQVIINcGALKAFRSLLSSPKENIRKEACWTISNIT--AGNTEQIQA 364
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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