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Conserved domains on  [gi|1370453708|ref|XP_024303889|]
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kelch domain-containing protein 8A isoform X1 [Homo sapiens]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 19803719)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
58-337 7.06e-46

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 157.63  E-value: 7.06e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  58 QWTALPRLPTARAGVAVTALGKRIMVIGGVGTNQlPLKVVEMYNIDEGKWKKR-SMLREAAMGISVTAKDYRVYAAGGMG 136
Cdd:COG3055     2 TWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGS-ASNSFEVYDPATNTWSELaPLPGPPRHHAAAVAQDGKLYVFGGFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 137 L---DLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKR- 212
Cdd:COG3055    81 GanpSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRd 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 213 AFSSFVTLDNHLYSLGGlrqgrlyrqpkflrtmDVFDMEQGGWLKMERsffLKKRRADFVAGSLSGRVIVAGGLGNqptV 292
Cdd:COG3055   161 HLAAAVLPDGKILVIGG----------------RNGSGFSNTWTTLAP---LPTARAGHAAAVLGGKILVFGGESG---F 218

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1370453708 293 LETAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVGGVNQG 337
Cdd:COG3055   219 SDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETKP 263
NanM super family cl34543
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-101 1.77e-11

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3055:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 64.02  E-value: 1.77e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  10 QWKRLAPLPSRRVYCSLLETGGQVYAIGGcdDNGVPMDCfEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVIGGVGT 89
Cdd:COG3055   186 TWTTLAPLPTARAGHAAAVLGGKILVFGG--ESGFSDEV-EAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETK 262

                          90
                  ....*....|....*
gi 1370453708  90 NQLP---LKVVEMYN 101
Cdd:COG3055   263 PGVRtplVTSAEVYD 277
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
58-337 7.06e-46

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 157.63  E-value: 7.06e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  58 QWTALPRLPTARAGVAVTALGKRIMVIGGVGTNQlPLKVVEMYNIDEGKWKKR-SMLREAAMGISVTAKDYRVYAAGGMG 136
Cdd:COG3055     2 TWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGS-ASNSFEVYDPATNTWSELaPLPGPPRHHAAAVAQDGKLYVFGGFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 137 L---DLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKR- 212
Cdd:COG3055    81 GanpSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRd 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 213 AFSSFVTLDNHLYSLGGlrqgrlyrqpkflrtmDVFDMEQGGWLKMERsffLKKRRADFVAGSLSGRVIVAGGLGNqptV 292
Cdd:COG3055   161 HLAAAVLPDGKILVIGG----------------RNGSGFSNTWTTLAP---LPTARAGHAAAVLGGKILVFGGESG---F 218

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1370453708 293 LETAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVGGVNQG 337
Cdd:COG3055   219 SDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETKP 263
PHA03098 PHA03098
kelch-like protein; Provisional
 5-209 4.89e-26

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 108.70  E-value: 4.89e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708   5 NVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDdNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVI 84
Cdd:PHA03098  317 DTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIY-NSISLNTVESWKPGESKWREEPPLIFPRYNPCVVNVNNLIYVI 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  85 GGVGTNQLPLKVVEMYNIDEGKWKKRSMLREAAMGISVTAKDYRVYAAGGMGLDLRPH--NHLQHYDMLKDMWVSLAPMP 162
Cdd:PHA03098  396 GGISKNDELLKTVECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGISYIDNIKvyNIVESYNPVTNKWTELSSLN 475

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1370453708 163 TPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIP 209
Cdd:PHA03098  476 FPRINASLCIFNNKIYVVGGDKYEYYINEIEVYDDKTNTWTLFCKFP 522
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-101 1.77e-11

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 64.02  E-value: 1.77e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  10 QWKRLAPLPSRRVYCSLLETGGQVYAIGGcdDNGVPMDCfEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVIGGVGT 89
Cdd:COG3055   186 TWTTLAPLPTARAGHAAAVLGGKILVFGG--ESGFSDEV-EAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETK 262

                          90
                  ....*....|....*
gi 1370453708  90 NQLP---LKVVEMYN 101
Cdd:COG3055   263 PGVRtplVTSAEVYD 277
PHA03098 PHA03098
kelch-like protein; Provisional
 1-108 6.10e-10

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 60.17  E-value: 6.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708   1 MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCD--DNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALG 78
Cdd:PHA03098  408 VECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGISyiDNIKVYNIVESYNPVTNKWTELSSLNFPRINASLCIFN 487

                          90       100       110
                  ....*....|....*....|....*....|
gi 1370453708  79 KRIMVIGGVgTNQLPLKVVEMYNIDEGKWK 108
Cdd:PHA03098  488 NKIYVVGGD-KYEYYINEIEVYDDKTNTWT 516
Kelch smart00612
Kelch domain;
32-79 9.59e-10

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 53.72  E-value: 9.59e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1370453708   32 QVYAIGGCDdNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGK 79
Cdd:smart00612   1 KIYVVGGFD-GGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 20-66 1.29e-08

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 50.30  E-value: 1.29e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1370453708  20 RRVYCSLLETGGQVYAIGGCDdNGVPMDCFEVYSPEADQWTALPRLP 66
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFD-GNQSLNSVEVYDPETNTWSKLPSMP 46
Kelch smart00612
Kelch domain;
279-326 1.59e-08

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 50.25  E-value: 1.59e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1370453708  279 RVIVAGGLGNQpTVLETAEAFHPGKNKWEILPAMPTPRCACSSIVVKN 326
Cdd:smart00612   1 KIYVVGGFDGG-QRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch_6 pfam13964
Kelch motif;
164-212 1.15e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 45.02  E-value: 1.15e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1370453708 164 PRYAATSFLRGSKIYVLGGR-QSKYAVNAFEVFDIETRSWTKFPNIPYKR 212
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYtNASPALNKLEVYNPLTKSWEELPPLPTPR 50
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
58-337 7.06e-46

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 157.63  E-value: 7.06e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  58 QWTALPRLPTARAGVAVTALGKRIMVIGGVGTNQlPLKVVEMYNIDEGKWKKR-SMLREAAMGISVTAKDYRVYAAGGMG 136
Cdd:COG3055     2 TWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGS-ASNSFEVYDPATNTWSELaPLPGPPRHHAAAVAQDGKLYVFGGFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 137 L---DLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKR- 212
Cdd:COG3055    81 GanpSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRd 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 213 AFSSFVTLDNHLYSLGGlrqgrlyrqpkflrtmDVFDMEQGGWLKMERsffLKKRRADFVAGSLSGRVIVAGGLGNqptV 292
Cdd:COG3055   161 HLAAAVLPDGKILVIGG----------------RNGSGFSNTWTTLAP---LPTARAGHAAAVLGGKILVFGGESG---F 218

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1370453708 293 LETAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVGGVNQG 337
Cdd:COG3055   219 SDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETKP 263
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
5-229 1.24e-36

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 133.36  E-value: 1.24e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708   5 NVKDFQWKRLAPLP-SRRVYCSLLETGGQVYAIGGCD---DNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGKR 80
Cdd:COG3055    44 DPATNTWSELAPLPgPPRHHAAAVAQDGKLYVFGGFTganPSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGK 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  81 IMVIGGVGTNQlPLKVVEMYNIDEGKWKKRSMLREAAMGIS-VTAKDYRVYAAGGmgldlrphnhlQHYDMLKDMWVSLA 159
Cdd:COG3055   124 IYVVGGWDDGG-NVAWVEVYDPATGTWTQLAPLPTPRDHLAaAVLPDGKILVIGG-----------RNGSGFSNTWTTLA 191

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 160 PMPTPRYAATSFLRGSKIYVLGGrqSKYAVNAFEVFDIETRSWTKFPNIPYKRAFSSFVTLDNHLYSLGG 229
Cdd:COG3055   192 PLPTARAGHAAAVLGGKILVFGG--ESGFSDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGG 259
PHA03098 PHA03098
kelch-like protein; Provisional
 5-209 4.89e-26

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 108.70  E-value: 4.89e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708   5 NVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDdNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVI 84
Cdd:PHA03098  317 DTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIY-NSISLNTVESWKPGESKWREEPPLIFPRYNPCVVNVNNLIYVI 395

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  85 GGVGTNQLPLKVVEMYNIDEGKWKKRSMLREAAMGISVTAKDYRVYAAGGMGLDLRPH--NHLQHYDMLKDMWVSLAPMP 162
Cdd:PHA03098  396 GGISKNDELLKTVECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGISYIDNIKvyNIVESYNPVTNKWTELSSLN 475

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1370453708 163 TPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIP 209
Cdd:PHA03098  476 FPRINASLCIFNNKIYVVGGDKYEYYINEIEVYDDKTNTWTLFCKFP 522
PHA03098 PHA03098
kelch-like protein; Provisional
 11-255 1.05e-25

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 107.55  E-value: 1.05e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  11 WKRLAPLPSRRVYCSLLETGgQVYAIGGCDDNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVIGGVGTN 90
Cdd:PHA03098  276 INTIIDIHYVYCFGSVVLNN-VIYFIGGMNKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIYNS 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  91 qLPLKVVEMYNIDEGKWKKRSMLREAAMGISVTAKDYRVYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATS 170
Cdd:PHA03098  355 -ISLNTVESWKPGESKWREEPPLIFPRYNPCVVNVNNLIYVIGGISKNDELLKTVECFSLNTNKWSKGSPLPISHYGGCA 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 171 FLRGSKIYVLGGRQSKYAVNAF---EVFDIETRSWTKFPNIPYKRAFSSFVTLDNHLYSLGGlrqgrlYRQPKFLRTMDV 247
Cdd:PHA03098  434 IYHDGKIYVIGGISYIDNIKVYnivESYNPVTNKWTELSSLNFPRINASLCIFNNKIYVVGG------DKYEYYINEIEV 507


                  ....*...
gi 1370453708 248 FDMEQGGW 255
Cdd:PHA03098  508 YDDKTNTW 515
PHA03098 PHA03098
kelch-like protein; Provisional
 129-333 4.83e-19

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 87.90  E-value: 4.83e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 129 VYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNI 208
Cdd:PHA03098  297 IYFIGGMNKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIYNSISLNTVESWKPGESKWREEPPL 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 209 PYKRAFSSFVTLDNHLYSLGGlrqgrLYRQPKFLRTMDVFDMEQGGWLKMERsffLKKRRADFVAGSLSGRVIVAGGLG- 287
Cdd:PHA03098  377 IFPRYNPCVVNVNNLIYVIGG-----ISKNDELLKTVECFSLNTNKWSKGSP---LPISHYGGCAIYHDGKIYVIGGISy 448

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1370453708 288 -NQPTVLETAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVGG 333
Cdd:PHA03098  449 iDNIKVYNIVESYNPVTNKWTELSSLNFPRINASLCIFNNKIYVVGG 495
PLN02153 PLN02153
epithiospecifier protein
 128-333 3.63e-16

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 78.49  E-value: 3.63e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 128 RVYAAGGmglDLRPHNHLQhydmlKDMWV--------SLAPM--PTPR---YAATSFLRGSKIYVLGGRQSKYAVNAFEV 194
Cdd:PLN02153   34 KLYSFGG---ELKPNEHID-----KDLYVfdfnthtwSIAPAngDVPRiscLGVRMVAVGTKLYIFGGRDEKREFSDFYS 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 195 FDIETRSWTKFPNI-----PYKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMER--SFFLKKR 267
Cdd:PLN02153  106 YDTVKNEWTFLTKLdeeggPEARTFHSMASDENHVYVFGGVSKGGLMKTPERFRTIEAYNIADGKWVQLPDpgENFEKRG 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370453708 268 RADFVAgsLSGRVIVAGGL-------GNQPTVLETAEAFHPGKNKW---EILPAMPTPRCACSSIVVKNCLLAVGG 333
Cdd:PLN02153  186 GAGFAV--VQGKIWVVYGFatsilpgGKSDYESNAVQFFDPASGKWtevETTGAKPSARSVFAHAVVGKYIIIFGG 259
PHA03098 PHA03098
kelch-like protein; Provisional
 165-335 4.83e-13

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 69.80  E-value: 4.83e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 165 RYAATSFLRGSKIYVLGGR-QSKYAVNAFEVFDIETRSWTKFPNIPYKRAFSSFVTLDNHLYSLGGLRQGRLyrqpkfLR 243
Cdd:PHA03098  285 VYCFGSVVLNNVIYFIGGMnKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIYNSIS------LN 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 244 TMDVFDMEQGGWlkmERSFFLKKRRADFVAGSLSGRVIVAGGLGNQPTVLETAEAFHPGKNKWEILPAMPTPRCACSSIV 323
Cdd:PHA03098  359 TVESWKPGESKW---REEPPLIFPRYNPCVVNVNNLIYVIGGISKNDELLKTVECFSLNTNKWSKGSPLPISHYGGCAIY 435

                         170
                  ....*....|..
gi 1370453708 324 VKNCLLAVGGVN 335
Cdd:PHA03098  436 HDGKIYVIGGIS 447
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-101 1.77e-11

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 64.02  E-value: 1.77e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  10 QWKRLAPLPSRRVYCSLLETGGQVYAIGGcdDNGVPMDCfEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVIGGVGT 89
Cdd:COG3055   186 TWTTLAPLPTARAGHAAAVLGGKILVFGG--ESGFSDEV-EAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETK 262

                          90
                  ....*....|....*
gi 1370453708  90 NQLP---LKVVEMYN 101
Cdd:COG3055   263 PGVRtplVTSAEVYD 277
PHA03098 PHA03098
kelch-like protein; Provisional
 1-108 6.10e-10

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 60.17  E-value: 6.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708   1 MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCD--DNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALG 78
Cdd:PHA03098  408 VECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGISyiDNIKVYNIVESYNPVTNKWTELSSLNFPRINASLCIFN 487

                          90       100       110
                  ....*....|....*....|....*....|
gi 1370453708  79 KRIMVIGGVgTNQLPLKVVEMYNIDEGKWK 108
Cdd:PHA03098  488 NKIYVVGGD-KYEYYINEIEVYDDKTNTWT 516
Kelch smart00612
Kelch domain;
32-79 9.59e-10

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 53.72  E-value: 9.59e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1370453708   32 QVYAIGGCDdNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGK 79
Cdd:smart00612   1 KIYVVGGFD-GGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 20-66 1.29e-08

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 50.30  E-value: 1.29e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1370453708  20 RRVYCSLLETGGQVYAIGGCDdNGVPMDCFEVYSPEADQWTALPRLP 66
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFD-GNQSLNSVEVYDPETNTWSKLPSMP 46
Kelch smart00612
Kelch domain;
279-326 1.59e-08

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 50.25  E-value: 1.59e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1370453708  279 RVIVAGGLGNQpTVLETAEAFHPGKNKWEILPAMPTPRCACSSIVVKN 326
Cdd:smart00612   1 KIYVVGGFDGG-QRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
PHA02790 PHA02790
Kelch-like protein; Provisional
 129-337 6.40e-08

Kelch-like protein; Provisional


Pssm-ID: 165153 [Multi-domain]  Cd Length: 480  Bit Score: 53.89  E-value: 6.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 129 VYAAGGMgLDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFevFDIETrSWTKFPNI 208
Cdd:PHA02790  274 VYLIGGW-MNNEIHNNAIAVNYISNNWIPIPPMNSPRLYASGVPANNKLYVVGGLPNPTSVERW--FHGDA-AWVNMPSL 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 209 PYKRAFSSFVTLDNHLYSLGGLRQGRlyrqpkflRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGSlsgRVIVAGglgn 288
Cdd:PHA02790  350 LKPRCNPAVASINNVIYVIGGHSETD--------TTTEYLLPNHDQWQFGPSTYYPHYKSCALVFGR---RLFLVG---- 414

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1370453708 289 qptvlETAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVGGVNQG 337
Cdd:PHA02790  415 -----RNAEFYCESSNTWTLIDDPIYPRDNPELIIVDNKLLLIGGFYRG 458
Kelch smart00612
Kelch domain;
176-222 5.13e-07

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 46.01  E-value: 5.13e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1370453708  176 KIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKRAFSSFVTLDN 222
Cdd:smart00612   1 KIYVVGGFDGGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
PLN02153 PLN02153
epithiospecifier protein
 21-248 6.56e-07

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 50.37  E-value: 6.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  21 RVYC---SLLETGGQVYAIGGCDDNGVPMDcFEVYSPEADQWTALPRL-----PTARAGVAVTALGKRIMVIGGV---GT 89
Cdd:PLN02153   73 RISClgvRMVAVGTKLYIFGGRDEKREFSD-FYSYDTVKNEWTFLTKLdeeggPEARTFHSMASDENHVYVFGGVskgGL 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  90 NQLP--LKVVEMYNIDEGKWKK-----RSMLREAAMGISVT-AKDYRVYAAGGM----GLDLRPHNHLQHYDMLKDMWVS 157
Cdd:PLN02153  152 MKTPerFRTIEAYNIADGKWVQlpdpgENFEKRGGAGFAVVqGKIWVVYGFATSilpgGKSDYESNAVQFFDPASGKWTE 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 158 L---APMPTPRYAATSFLRGSKIYVLGGR-----QSKYA----VNAFEVFDIETRSWTKF-----PNIPykRAFSSFVTL 220
Cdd:PLN02153  232 VettGAKPSARSVFAHAVVGKYIIIFGGEvwpdlKGHLGpgtlSNEGYALDTETLVWEKLgecgePAMP--RGWTAYTTA 309

                         250       260       270
                  ....*....|....*....|....*....|
gi 1370453708 221 DnhLYSLGGL--RQGRLyrqPKFLRTMDVF 248
Cdd:PLN02153  310 T--VYGKNGLlmHGGKL---PTNERTDDLY 334
Kelch_6 pfam13964
Kelch motif;
164-212 1.15e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 45.02  E-value: 1.15e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1370453708 164 PRYAATSFLRGSKIYVLGGR-QSKYAVNAFEVFDIETRSWTKFPNIPYKR 212
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYtNASPALNKLEVYNPLTKSWEELPPLPTPR 50
PLN02193 PLN02193
nitrile-specifier protein
 128-333 1.33e-06

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 49.95  E-value: 1.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 128 RVYAAGGMGLDLRP-HNHLQHYDMLKDMWvSLAP----MPTPRYAATSFLR-GSKIYVLGGRQSKYAVNAFEVFDIETRS 201
Cdd:PLN02193  177 KIYSFGGEFTPNQPiDKHLYVFDLETRTW-SISPatgdVPHLSCLGVRMVSiGSTLYVFGGRDASRQYNGFYSFDTTTNE 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 202 W---TKFPNIPYKRAFSSFVTLDNHLYSLGGLrqGRLYRqpkfLRTMDVFDMEQGGWlkmersFFLKKRRADFVAGSLSG 278
Cdd:PLN02193  256 WkllTPVEEGPTPRSFHSMAADEENVYVFGGV--SATAR----LKTLDSYNIVDKKW------FHCSTPGDSFSIRGGAG 323

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370453708 279 RVIVAGGL----GNQPTVLETAEAFHPGKNKW---EILPAMPTPRCACSSIVVKNCLLAVGG 333
Cdd:PLN02193  324 LEVVQGKVwvvyGFNGCEVDDVHYYDPVQDKWtqvETFGVRPSERSVFASAAVGKHIVIFGG 385
Kelch_6 pfam13964
Kelch motif;
21-69 8.29e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 42.71  E-value: 8.29e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1370453708  21 RVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTALPRLPTAR 69
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 68-109 1.94e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 41.44  E-value: 1.94e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1370453708  68 ARAGVAVTALGKRIMVIGGVGTNQlPLKVVEMYNIDEGKWKK 109
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQ-SLNSVEVYDPETNTWSK 41
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 267-313 2.50e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 41.06  E-value: 2.50e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1370453708 267 RRADFVAGSLSGRVIVAGGLGNQpTVLETAEAFHPGKNKWEILPAMP 313
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGN-QSLNSVEVYDPETNTWSKLPSMP 46
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 164-207 3.07e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 40.67  E-value: 3.07e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1370453708 164 PRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPN 207
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLPS 44
Kelch_6 pfam13964
Kelch motif;
275-316 5.75e-05

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 40.01  E-value: 5.75e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1370453708 275 SLSGRVIVAGGLGNQPTVLETAEAFHPGKNKWEILPAMPTPR 316
Cdd:pfam13964   9 SVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
Kelch_3 pfam13415
Galactose oxidase, central domain;
30-77 6.78e-05

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 39.97  E-value: 6.78e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1370453708  30 GGQVYAIGGCDDNGVPMDC-FEVYSPEADQWTALPRLPTARAGVAVTAL 77
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNdLYVYDLDTNTWTQIGDLPPPRSGHSATYI 49
Kelch smart00612
Kelch domain;
128-170 4.55e-04

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 37.54  E-value: 4.55e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1370453708  128 RVYAAGGMGlDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATS 170
Cdd:smart00612   1 KIYVVGGFD-GGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGV 42
Kelch_6 pfam13964
Kelch motif;
118-165 1.18e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.54  E-value: 1.18e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1370453708 118 MGISVTAKDYRVYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAPMPTPR 165
Cdd:pfam13964   3 TFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
PHA02713 PHA02713
hypothetical protein; Provisional
 14-86 1.19e-03

hypothetical protein; Provisional


Pssm-ID: 165086 [Multi-domain]  Cd Length: 557  Bit Score: 40.76  E-value: 1.19e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370453708  14 LAPLPSRRVYCSLLETGGQVYAIGGcdDNGVPMD-CFEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVIGG 86
Cdd:PHA02713  335 LPPMIKNRCRFSLAVIDDTIYAIGG--QNGTNVErTIECYTMGDDKWKMLPDMPIALSSYGMCVLDQYIYIIGG 406
Kelch_4 pfam13418
Galactose oxidase, central domain;
267-314 1.40e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.05  E-value: 1.40e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1370453708 267 RRADFVAGSL-SGRVIVAGGLGNQPTVLETAEAFHPGKNKWEILPAMPT 314
Cdd:pfam13418   1 PRAYHTSTSIpDDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLGSLPS 49
Kelch smart00612
Kelch domain;
80-124 1.46e-03

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 36.00  E-value: 1.46e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1370453708   80 RIMVIGGVGTNQlPLKVVEMYNIDEGKWKKRSMLREAAMGISVTA 124
Cdd:smart00612   1 KIYVVGGFDGGQ-RLKSVEVYDPETNKWTPLPSMPTPRSGHGVAV 44
PHA02790 PHA02790
Kelch-like protein; Provisional
 138-332 1.60e-03

Kelch-like protein; Provisional


Pssm-ID: 165153 [Multi-domain]  Cd Length: 480  Bit Score: 40.03  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 138 DLRPHNHLQH----YDMLKDMWVSLAPMPTPRYAatsflrGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKRA 213
Cdd:PHA02790  237 DKQPRKSYKYpfieYPMNMDQIIDIFHMCTSTHV------GEVVYLIGGWMNNEIHNNAIAVNYISNNWIPIPPMNSPRL 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 214 FSSFVTLDNHLYSLGGLrqgrlyrqPKFLRTMDVFDMEQgGWLKMERsffLKKRRADFVAGSLSGRVIVAGGLGNQPTvl 293
Cdd:PHA02790  311 YASGVPANNKLYVVGGL--------PNPTSVERWFHGDA-AWVNMPS---LLKPRCNPAVASINNVIYVIGGHSETDT-- 376

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1370453708 294 eTAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVG 332
Cdd:PHA02790  377 -TTEYLLPNHDQWQFGPSTYYPHYKSCALVFGRRLFLVG 414
Kelch_4 pfam13418
Galactose oxidase, central domain;
164-210 2.05e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 35.67  E-value: 2.05e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1370453708 164 PR-YAATSFLRGSKIYVLGGRQSKYAV-NAFEVFDIETRSWTKFPNIPY 210
Cdd:pfam13418   1 PRaYHTSTSIPDDTIYLFGGEGEDGTLlSDLWVFDLSTNEWTRLGSLPS 49
PHA02713 PHA02713
hypothetical protein; Provisional
 99-252 2.95e-03

hypothetical protein; Provisional


Pssm-ID: 165086 [Multi-domain]  Cd Length: 557  Bit Score: 39.61  E-value: 2.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  99 MYNIDEGKWKKRSMLREAAMGISVTAKDYRVYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIY 178
Cdd:PHA02713  276 VYNINTMEYSVISTIPNHIINYASAIVDNEIIIAGGYNFNNPSLNKVYKINIENKIHVELPPMIKNRCRFSLAVIDDTIY 355

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370453708 179 VLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKRAFSSFVTLDNHLYSLGGLRQGRLYRQpkfLRTMDVFDMEQ 252
Cdd:PHA02713  356 AIGGQNGTNVERTIECYTMGDDKWKMLPDMPIALSSYGMCVLDQYIYIIGGRTEHIDYTS---VHHMNSIDMEE 426
PHA02790 PHA02790
Kelch-like protein; Provisional
 24-255 5.62e-03

Kelch-like protein; Provisional


Pssm-ID: 165153 [Multi-domain]  Cd Length: 480  Bit Score: 38.49  E-value: 5.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  24 CSLLETGGQVYAIGGCDDN-----GVPMDCFevyspeADQWTALPRLPTARAGVAVTALGKRIMVIGGVGTnqlPLKVVE 98
Cdd:PHA02790  265 CTSTHVGEVVYLIGGWMNNeihnnAIAVNYI------SNNWIPIPPMNSPRLYASGVPANNKLYVVGGLPN---PTSVER 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708  99 MYNIDEgKWKKRSMLREAAMGISVTAKDYRVYAAGGMG-LDLRPHNHLQHYDMlkdmWVSLAPMPTPRYAATSFLRGSKI 177
Cdd:PHA02790  336 WFHGDA-AWVNMPSLLKPRCNPAVASINNVIYVIGGHSeTDTTTEYLLPNHDQ----WQFGPSTYYPHYKSCALVFGRRL 410

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370453708 178 YVLGgRQSKYAVNAfevfdieTRSWTKFPNIPYKRAFSSFVTLDNHLYSLGGLRQGrlyrqpKFLRTMDVFDMEQGGW 255
Cdd:PHA02790  411 FLVG-RNAEFYCES-------SNTWTLIDDPIYPRDNPELIIVDNKLLLIGGFYRG------SYIDTIEVYNNRTYSW 474
PRK14131 PRK14131
N-acetylneuraminate epimerase;
155-229 5.69e-03

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 38.46  E-value: 5.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453708 155 WVSLAPMPT-PRYAATSFLRGSKIYVLGGRQ------SKYAVNAFEVFDIETRSWTKFPNI-PYKRAFSSFVTLDN-HLY 225
Cdd:PRK14131   64 WTKIAAFPGgPREQAVAAFIDGKLYVFGGIGktnsegSPQVFDDVYKYDPKTNSWQKLDTRsPVGLAGHVAVSLHNgKAY 143


                  ....
gi 1370453708 226 SLGG 229
Cdd:PRK14131  144 ITGG 147
Kelch_4 pfam13418
Galactose oxidase, central domain;
68-111 6.91e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 34.12  E-value: 6.91e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1370453708  68 ARAGVAVTALGK-RIMVIGGVGTNQLPLKVVEMYNIDEGKWKKRS 111
Cdd:pfam13418   1 PRAYHTSTSIPDdTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLG 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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