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Conserved domains on  [gi|1370453736|ref|XP_024303929|]
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enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X6 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
38-242 1.37e-65

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 203.88  E-value: 1.37e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600    1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 116 --------------------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLS 147
Cdd:PLN02600   81 fsslealsiptiavvegaalggglelALSCDLricgeeavfglpetglaiipgaGGTQRLPRLVGRSRAKELIFTGRRIG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 148 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 227
Cdd:PLN02600  161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                         250
                  ....*....|....*
gi 1370453736 228 MAAFREKRTPKFVGK 242
Cdd:PLN02600  237 LAAFAEKRKPVYTGK 251
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
38-242 1.37e-65

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 203.88  E-value: 1.37e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600    1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 116 --------------------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLS 147
Cdd:PLN02600   81 fsslealsiptiavvegaalggglelALSCDLricgeeavfglpetglaiipgaGGTQRLPRLVGRSRAKELIFTGRRIG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 148 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 227
Cdd:PLN02600  161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                         250
                  ....*....|....*
gi 1370453736 228 MAAFREKRTPKFVGK 242
Cdd:PLN02600  237 LAAFAEKRKPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
41-235 4.95e-43

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 145.69  E-value: 4.95e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:COG1024     8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 120 --------------------------------------------------DIGGTQRLPRCLGVALAKELIFTGRRLSGT 149
Cdd:COG1024    87 alrrlpkpviaavngaalggglelalacdlriaaedarfglpevrlglipGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 150 EAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 229
Cdd:COG1024   167 EALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242

                  ....*.
gi 1370453736 230 AFREKR 235
Cdd:COG1024   243 AFLEKR 248
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
40-242 1.99e-29

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 110.53  E-value: 1.99e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVF-------VQ 112
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYrenvldlWT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 113 RLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGT 149
Cdd:pfam00378  83 LLYtcpkpviaavngyaigggcelalacdiiiaadnasfglnetklGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 150 EAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 229
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQ 238
                         250
                  ....*....|...
gi 1370453736 230 AFREKRTPKFVGK 242
Cdd:pfam00378 239 AFLEKRKPPWEDQ 251
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
39-181 7.51e-28

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 104.95  E-value: 7.51e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGV--------- 109
Cdd:cd06558     6 DGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAGEEArafirelqe 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 110 FVQRLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRL 146
Cdd:cd06558    85 LLRALLrlpkpviaavngaalggglelalacdiriaaedakfglpevklGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1370453736 147 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 181
Cdd:cd06558   165 SAEEALELGLVDEVV----PDEELLAAALELARRL 195
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-198 9.01e-07

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 49.45  E-value: 9.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGAD---------LKEREQMS-EAEVGV 109
Cdd:TIGR02441  22 DVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADiqmiaacktAQEVTQLSqEGQEMF 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 110 F-VQR------------------------------------------LRGLMNDIGGTQRLPRCLGVALAKELIFTGRRL 146
Cdd:TIGR02441 102 ErIEKsqkpivaaisgsclggglelalachyriatkdrktllglpevMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKI 181
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1370453736 147 SGTEAHVLGLVNHAVAQNEEG-DAAYQRARALAQEILPQAPIAVRLGKVAIDR 198
Cdd:TIGR02441 182 RADRAKKMGIVDQLVDPLGPGlKPAEENTIEYLEEVAVKFAQGLANGKLSINR 234
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
38-242 1.37e-65

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 203.88  E-value: 1.37e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLR-- 115
Cdd:PLN02600    1 PDSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRst 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 116 --------------------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLS 147
Cdd:PLN02600   81 fsslealsiptiavvegaalggglelALSCDLricgeeavfglpetglaiipgaGGTQRLPRLVGRSRAKELIFTGRRIG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 148 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 227
Cdd:PLN02600  161 AREAASMGLVNYCVPAGE----AYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEG 236
                         250
                  ....*....|....*
gi 1370453736 228 MAAFREKRTPKFVGK 242
Cdd:PLN02600  237 LAAFAEKRKPVYTGK 251
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
39-242 3.26e-57

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 182.63  E-value: 3.26e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK07657   11 TPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTM 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 119 NDI--------------------------------------------------GGTQRLPRCLGVALAKELIFTGRRLSG 148
Cdd:PRK07657   91 EMVeqlpqpviaaingialggglelalacdfriaaesaslgltettlaiipgaGGTQRLPRLIGVGRAKELIYTGRRISA 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 149 TEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 228
Cdd:PRK07657  171 QEAKEIGLVEFVVPAHL----LEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKDRLEGL 246
                         250
                  ....*....|....
gi 1370453736 229 AAFREKRTPKFVGK 242
Cdd:PRK07657  247 QAFKEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
41-235 4.95e-43

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 145.69  E-value: 4.95e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE-REQMSEAEVGVFVQRLRGLMN 119
Cdd:COG1024     8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 120 --------------------------------------------------DIGGTQRLPRCLGVALAKELIFTGRRLSGT 149
Cdd:COG1024    87 alrrlpkpviaavngaalggglelalacdlriaaedarfglpevrlglipGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 150 EAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 229
Cdd:COG1024   167 EALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242

                  ....*.
gi 1370453736 230 AFREKR 235
Cdd:COG1024   243 AFLEKR 248
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
39-242 9.11e-37

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 129.87  E-value: 9.11e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAE---VGVFVQRL- 114
Cdd:PRK05809   11 EGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEgrkFGLLGNKVf 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 115 RGLMN------------------------DI----------------------GGTQRLPRCLGVALAKELIFTGRRLSG 148
Cdd:PRK05809   91 RKLENldkpviaaingfalgggcelsmacDIriasekakfgqpevglgitpgfGGTQRLARIVGPGKAKELIYTGDMINA 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 149 TEAHVLGLVNHAVAQNEEGDAAYqrarALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 228
Cdd:PRK05809  171 EEALRIGLVNKVVEPEKLMEEAK----ALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGM 246
                         250
                  ....*....|....
gi 1370453736 229 AAFREKRTPKFVGK 242
Cdd:PRK05809  247 TAFVEKREKNFKNK 260
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
39-242 1.22e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 119.20  E-value: 1.22e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE------REQMSEAEVGVFVQ 112
Cdd:PRK06688   12 EDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLT-GAGRAFSAGGDIKDfpkappKPPDELAPVNRFLR 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 113 RLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGT 149
Cdd:PRK06688   91 AIAalpkpvvaavngpavgvgvslalacdlvyasesakfslpfaklGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSAE 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 150 EAHVLGLVNHAVAqNEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 229
Cdd:PRK06688  171 EALRIGLVNRVVP-AAELDAE---ADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGAT 246
                         250
                  ....*....|...
gi 1370453736 230 AFREKRTPKFVGK 242
Cdd:PRK06688  247 AFIEKRKPDFTGF 259
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
40-242 1.99e-29

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 110.53  E-value: 1.99e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKEREQMSEAEVGVF-------VQ 112
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYrenvldlWT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 113 RLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGT 149
Cdd:pfam00378  83 LLYtcpkpviaavngyaigggcelalacdiiiaadnasfglnetklGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 150 EAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMA 229
Cdd:pfam00378 163 EALKWGLVDKVVPEDQLLD----EARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQ 238
                         250
                  ....*....|...
gi 1370453736 230 AFREKRTPKFVGK 242
Cdd:pfam00378 239 AFLEKRKPPWEDQ 251
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
35-242 4.49e-28

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 107.16  E-value: 4.49e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  35 LAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEreqMSEAEVGVFV--- 111
Cdd:PRK09674    5 LVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVIT-GNARFFAAGADLNE---MAEKDLAATLndp 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 112 -----QRLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTG 143
Cdd:PRK09674   81 rpqlwQRLQafnkpliaavngyalgagcelallcdiviagenarfglpeitlGIMPGAGGTQRLIRSVGKSLASQMVLTG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 144 RRLSGTEAHVLGLVNHaVAQNEegdAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRD 223
Cdd:PRK09674  161 ESITAQQAQQAGLVSE-VFPPE---LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATED 236
                         250
                  ....*....|....*....
gi 1370453736 224 RLEGMAAFREKRTPKFVGK 242
Cdd:PRK09674  237 RHEGISAFLEKRTPDFKGR 255
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
39-181 7.51e-28

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 104.95  E-value: 7.51e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSEAEVGV--------- 109
Cdd:cd06558     6 DGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLT-GAGKAFCAGADLKELAALSDAGEEArafirelqe 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 110 FVQRLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRL 146
Cdd:cd06558    85 LLRALLrlpkpviaavngaalggglelalacdiriaaedakfglpevklGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1370453736 147 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEI 181
Cdd:cd06558   165 SAEEALELGLVDEVV----PDEELLAAALELARRL 195
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
38-242 2.26e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 105.52  E-value: 2.26e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEV---------- 107
Cdd:PRK08138   14 PADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIKEFATAGAIEMylrhterywe 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 108 ------------------------------------GVFVQ---RLrGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSG 148
Cdd:PRK08138   93 aiaqcpkpviaavngyalgggcelamhadiivagesASFGQpeiKV-GLMPGAGGTQRLVRAVGKFKAMRMALTGCMVPA 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 149 TEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 228
Cdd:PRK08138  172 PEALAIGLVSEVV----EDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQKEGM 247
                         250
                  ....*....|....
gi 1370453736 229 AAFREKRTPKFVGK 242
Cdd:PRK08138  248 DAFLEKRKPAYKGK 261
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
39-242 1.68e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 103.18  E-value: 1.68e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE------REQMSE-AEVG-VF 110
Cdd:PRK07658    9 EDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIH-GEGRFFSAGADIKEftsvteAEQATElAQLGqVT 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 111 VQRLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLS 147
Cdd:PRK07658   87 FERVEkfskpviaaihgaalggglelamschirfatesaklglpelnlGLIPGFAGTQRLPRYVGKAKALEMMLTSEPIT 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 148 GTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEG 227
Cdd:PRK07658  167 GAEALKWGLVNGVFPEET----LLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEG 242
                         250
                  ....*....|....*
gi 1370453736 228 MAAFREKRTPKFVGK 242
Cdd:PRK07658  243 VQAFLEKRKPSFSGK 257
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
45-239 6.68e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 93.57  E-value: 6.68e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEV--GVF------VQRLR- 115
Cdd:PRK05862   17 ITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVI-TGSEKAFAAGADIKEMADLSFMDVykGDYitnwekVARIRk 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 116 -----------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 156
Cdd:PRK05862   96 pviaavagyalgggcelAMMCDIiiaadtakfgqpeiklgvlpgmGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERAGL 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 157 VNHAVAQNEEGDAAYQRARALAQEILPqapiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREKRT 236
Cdd:PRK05862  176 VSRVVPADKLLDEALAAATTIASFSLP----AVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVEKRK 251

                  ...
gi 1370453736 237 PKF 239
Cdd:PRK05862  252 PVF 254
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
39-242 4.57e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 91.26  E-value: 4.57e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSE-------------- 104
Cdd:PRK06494   11 KGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKrgwpesgfggltsr 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 105 -------------------------------AEVGVFV--QRLRGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEA 151
Cdd:PRK06494   91 fdldkpiiaavngvamgggfelalacdlivaAENATFAlpEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREG 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 152 HVLGLVNHAVAQnEEGDAAyqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQN--IPTRDRLEGMA 229
Cdd:PRK06494  171 LELGFVNEVVPA-GELLAA---AERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRDYPAVEarRASQDYIEGPK 246
                         250
                  ....*....|...
gi 1370453736 230 AFREKRTPKFVGK 242
Cdd:PRK06494  247 AFAEKRPPRWKGR 259
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
39-240 2.56e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 89.17  E-value: 2.56e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PRK07509   10 EDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRaVIL--SGEGGAFCAGLDVKSVASSPGNAVKLLFKRLPGN 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 118 MN---------------------------------------------------------DIGGTQRLPRCLGVALAKELI 140
Cdd:PRK07509   88 ANlaqrvslgwrrlpvpviaalegvcfggglqialgadiriaapdtklsimeakwglvpDMAGTVSLRGLVRKDVARELT 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 141 FTGRRLSGTEAHVLGLVNHAVaqneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP 220
Cdd:PRK07509  168 YTARVFSAEEALELGLVTHVS------DDPLAAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQIRLLL 241
                         250       260
                  ....*....|....*....|
gi 1370453736 221 TRDRLEGMAAFREKRTPKFV 240
Cdd:PRK07509  242 GKNQKIAVKAQMKKRAPKFL 261
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
41-239 3.02e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 89.05  E-value: 3.02e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKE------------------REQM 102
Cdd:PRK05980   12 GIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEfsasvaagadvalrdfvrRGQA 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 103 SEAEVGVFVQRLRGLMNDI------------------------------------GGTQRLPRCLGVALAKELIFTGRRL 146
Cdd:PRK05980   92 MTARLEAFPKPVIAAVNGLafgggceiteavhlaiaseralfakpeirlgmpptfGGTQRLPRLAGRKRALELLLTGDAF 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 147 SGTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLE 226
Cdd:PRK05980  172 SAERALEIGLVNAVVPH----EELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLRE 247
                         250
                  ....*....|...
gi 1370453736 227 GMAAFREKRTPKF 239
Cdd:PRK05980  248 GLAAWIERRRPAY 260
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
38-239 5.45e-21

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 88.81  E-value: 5.45e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE----REQMSEAEVGVFVQR 113
Cdd:PLN02664   14 PNSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIIL-SGAGDHFCSGIDLKTlnsiSEQSSSGDRGRSGER 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 114 LR---------------------------------------------------------GLMNDIGGTQRLPRCLGVALA 136
Cdd:PLN02664   93 LRrkikflqdaitaieqcrkpviaaihgacigggvdivtacdirycsedaffsvkevdlAITADLGTLQRLPSIVGYGNA 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 137 KELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDaayQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYA 216
Cdd:PLN02664  173 MELALTGRRFSGSEAKELGLVSRVFGSKEDLD---EGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNS 249
                         250       260
                  ....*....|....*....|...
gi 1370453736 217 QNIPTRDRLEGMAAFREKRTPKF 239
Cdd:PLN02664  250 AMLVSDDLNEAVSAQIQKRKPVF 272
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
28-242 5.56e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 88.61  E-value: 5.56e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  28 SEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEV 107
Cdd:PRK06127    7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAE 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 108 GVF--------------------VQRLRG----------LMNDI----------------------GGTQRLPRCLGVAL 135
Cdd:PRK06127   87 AVAayeqaveaaqaaladyakptIACIRGycigggmgiaLACDIriaaedsrfgipaarlglgygyDGVKNLVDLVGPSA 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 136 AKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDR----GTEVDIASGMAIE 211
Cdd:PRK06127  167 AKDLFYTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAG----NAPLTLRAAKRAIAEllkdEPERDMAACQALV 242
                         250       260       270
                  ....*....|....*....|....*....|.
gi 1370453736 212 GMCYAqnipTRDRLEGMAAFREKRTPKFVGK 242
Cdd:PRK06127  243 AACFD----SEDYREGRAAFMEKRKPVFKGR 269
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
41-233 9.19e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 87.72  E-value: 9.19e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE--------REQMSEAEVGVFVQ 112
Cdd:PRK06190   13 RVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVL-TGADPAFCAGLDLKElggdgsayGAQDALPNPSPAWP 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 113 RLR----------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 152
Cdd:PRK06190   92 AMRkpvigaingaavtgglelalacdiliaserarfadtharvGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAADAL 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 153 VLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEgMCYAQNIPTRDRLEGMAAFR 232
Cdd:PRK06190  172 RAGLVTEVVPHDE----LLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALE-AEAARAHNRSVSPDGIAARR 246

                  .
gi 1370453736 233 E 233
Cdd:PRK06190  247 E 247
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
39-242 1.80e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 86.97  E-value: 1.80e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGV----FVQRL 114
Cdd:PRK06144   15 RGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAVayerRIDRV 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 115 RGLMND-------------IGG-----------------------------------TQRLPRCLGVALAKELIFTGRRL 146
Cdd:PRK06144   95 LGALEQlrvptiaaiagacVGGgaaiaaacdlriatpsarfgfpiartlgnclsmsnLARLVALLGAARVKDMLFTARLL 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 147 SGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAqnipTRDRLE 226
Cdd:PRK06144  175 EAEEALAAGLVNEVV----EDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDGDDLIRMCYM----SEDFRE 246
                         250
                  ....*....|....*.
gi 1370453736 227 GMAAFREKRTPKFVGK 242
Cdd:PRK06144  247 GVEAFLEKRPPKWKGR 262
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
47-241 4.11e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 86.20  E-value: 4.11e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  47 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAE-------VGVFVQRLR- 115
Cdd:PRK07511   18 LSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVL-TGAGGFFCAGGNLNrllENRAKPPSVqaasidgLHDWIRAIRa 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 116 ------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 153
Cdd:PRK07511   97 fpkpviaavegaaagagfslalacdllvaardakfvmayvkvGLTPDGGGSWFLARALPRQLATELLLEGKPISAERLHA 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 154 LGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFRE 233
Cdd:PRK07511  177 LGVVNRLAEPGQALAEALALADQLAA----GSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLE 252

                  ....*...
gi 1370453736 234 KRTPKFVG 241
Cdd:PRK07511  253 KRAPDYKR 260
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
41-242 4.54e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 85.81  E-value: 4.54e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-----EREQMSEAEVGVFVQR-- 113
Cdd:PRK08252   12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGIL-TGAGGTFCAGMDLKafargERPSIPGRGFGGLTERpp 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 114 ---------------------------------------LRGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 154
Cdd:PRK08252   91 rkpliaavegyalaggfelalacdlivaardakfglpevKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAERAHEL 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 155 GLVNHAVAQNEEGDAayqrARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFREK 234
Cdd:PRK08252  171 GLVNRLTEPGQALDA----ALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAKEGATAFAEK 246

                  ....*...
gi 1370453736 235 RTPKFVGK 242
Cdd:PRK08252  247 RAPVWTGK 254
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
39-237 6.47e-20

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 85.76  E-value: 6.47e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEreqMSEAEVGVFVQRLRG-- 116
Cdd:PRK08139   18 RDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKE---MRAARGLAYFRALFArc 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 117 --LMNDIggtQRLPR------------------------------------------CL--GVAL--------AKELIFT 142
Cdd:PRK08139   94 srVMQAI---VALPQpviarvhgiataagcqlvascdlavaadtarfavpgvniglfCStpMVALsrnvprkqAMEMLLT 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 143 GRRLSGTEAHVLGLVNHAVAQNEEGDAAyqraRALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTR 222
Cdd:PRK08139  171 GEFIDAATAREWGLVNRVVPADALDAAV----ARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMMAE 246
                         250
                  ....*....|....*
gi 1370453736 223 DRLEGMAAFREKRTP 237
Cdd:PRK08139  247 DAEEGIDAFLEKRPP 261
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
39-241 6.74e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 85.80  E-value: 6.74e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADL-----------KEREQMSEAEV 107
Cdd:PRK06142   13 ADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLpamagvfgqlgKDGLARPRTDL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 108 GVFVQRLRGLMN--------------------------------------------------DIGGTQRLPRCLGVALAK 137
Cdd:PRK06142   92 RREILRLQAAINavadcrkpviaavqgwcigggvdlisacdmryasadakfsvrevdlgmvaDVGSLQRLPRIIGDGHLR 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 138 ELIFTGRRLSGTEAHVLGLVNHAVaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQ 217
Cdd:PRK06142  172 ELALTGRDIDAAEAEKIGLVNRVY---DDADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAA 248
                         250       260
                  ....*....|....*....|....
gi 1370453736 218 NIPTRDRLEGMAAFREKRTPKFVG 241
Cdd:PRK06142  249 MLPSKDLTEAIAAHMEKRPPEFTG 272
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
39-242 3.91e-19

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 83.59  E-value: 3.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKERE--QMSEAEVGV--F--VQ 112
Cdd:PRK03580   10 NGSILEITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAegEAPDADFGPggFagLT 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 113 RLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGT 149
Cdd:PRK03580   89 EIFdldkpviaavngyafgggfelalaadfivcadnasfalpeaklGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAE 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 150 EAHVLGLVNHAVAQNEEGDaayqRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP----TRDRL 225
Cdd:PRK03580  169 EALRWGIVNRVVPQAELMD----RARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYPsvlhSEDAL 244
                         250
                  ....*....|....*..
gi 1370453736 226 EGMAAFREKRTPKFVGK 242
Cdd:PRK03580  245 EGPRAFAEKRDPVWKGR 261
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
39-242 2.94e-18

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 80.89  E-value: 2.94e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEvGVFVQRLR--- 115
Cdd:PRK06495   11 SDHVAVVTLDNPPV-NALSRELRDELIAVFDEISERPDVRVVVL-TGAGKVFCAGADLKGRPDVIKGP-GDLRAHNRrtr 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 116 --------------------------GLM--NDI-------------------GGTQRLPRCLGVALAKELIFTGRRLSG 148
Cdd:PRK06495   88 ecfhairecakpviaavngpalgaglGLVasCDIivasenavfglpeidvglaGGGKHAMRLFGHSLTRRMMLTGYRVPA 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 149 TEAHVLGLVNHAVAqneeGDAAYQRARALAQEILPQAPIAVRLGKVAIDrgtevdIASGMAI-EGMCYAQNIP-----TR 222
Cdd:PRK06495  168 AELYRRGVIEACLP----PEELMPEAMEIAREIASKSPLATRLAKDALN------TIENMSLrDGYRYEQDITaklakTE 237
                         250       260
                  ....*....|....*....|
gi 1370453736 223 DRLEGMAAFREKRTPKFVGK 242
Cdd:PRK06495  238 DAKEAQRAFLEKRPPVFKGR 257
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
42-242 1.10e-17

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 79.69  E-value: 1.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  42 ITEILMNRPSARNALGNVFVSELLETLAQLREDRqVRVLLFRSGVKG-VFCAGADLKEREQ------------------- 101
Cdd:PRK11423   14 IATITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHELPSggrdplsyddplrqilrmi 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 102 ---------MSEAEV--GVFVQRLR-------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEA 151
Cdd:PRK11423   93 qkfpkpviaMVEGSVwgGAFELIMScdliiaaststfamtpanlGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQRA 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 152 HVLGLVNHaVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKvaidrgTEVDI---ASGMAIEGMCYAQNI-----PTRD 223
Cdd:PRK11423  173 LAVGILNH-VVEVEELEDF---TLQMAHHISEKAPLAIAVIK------EQLRVlgeAHPMNPDEFERIQGLrravyDSED 242
                         250
                  ....*....|....*....
gi 1370453736 224 RLEGMAAFREKRTPKFVGK 242
Cdd:PRK11423  243 YQEGMNAFLEKRKPVFVGH 261
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
39-242 3.05e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 78.59  E-value: 3.05e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMSE-------------- 104
Cdd:PRK06210   13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGADMGELQTIDPsdgrrdtdvrpfvg 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 105 --------------------------AEVGV-FVQRL-------------------RGLMNDIGGTQRLPRCLGVALAKE 138
Cdd:PRK06210   92 nrrpdyqtryhfltalrkpviaaingACAGIgLTHALmcdvrfaadgakfttafarRGLIAEHGISWILPRLVGHANALD 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 139 LIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPqAPIAVRLGKVAIDRGTEVDIASGMAIEGMcyAQN 218
Cdd:PRK06210  172 LLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNVSP-ASMAVIKRQLYEDAFQTLAEATARANREM--HES 248
                         250       260
                  ....*....|....*....|....
gi 1370453736 219 IPTRDRLEGMAAFREKRTPKFVGK 242
Cdd:PRK06210  249 LQRPDFIEGVASFLEKRPPRFPGL 272
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
47-242 4.81e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 77.70  E-value: 4.81e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  47 MNRPSARNAL-GNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK---EREQMSEAEVGVFVQRLR------- 115
Cdd:PRK09245   18 MNRPETRNALsDNDAVDALVAACAAINADRSVRAVIL-TGAGTAFSSGGNVKdmrARVGAFGGSPADIRQGYRhgiqrip 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 116 -------------------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSG 148
Cdd:PRK09245   97 lalynlevpviaavngpaigagcdlACMCDIriasetarfaesfvklglipgdGGAWLLPRIIGMARAAEMAFTGDAIDA 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 149 TEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 228
Cdd:PRK09245  177 ATALEWGLVSRVVPA----DQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQALAHHTADHREAV 252
                         250
                  ....*....|....
gi 1370453736 229 AAFREKRTPKFVGK 242
Cdd:PRK09245  253 DAFLEKRPPVFTGR 266
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
47-242 9.73e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 77.06  E-value: 9.73e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  47 MNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK------EREQMSE---------------- 104
Cdd:PRK07799   20 MNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKaatkkpPGDSFKDgsydpsridallkgrr 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 105 --------------------------------AEVGVFVQRlRGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAH 152
Cdd:PRK07799   99 ltkpliaavegpaiaggteilqgtdirvagesAKFGISEAK-WSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAK 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 153 VLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 232
Cdd:PRK07799  178 EIGLIGHVVPD----GQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEGPRAFA 253
                         250
                  ....*....|
gi 1370453736 233 EKRTPKFVGK 242
Cdd:PRK07799  254 EKRAPNFQGR 263
PLN02888 PLN02888
enoyl-CoA hydratase
41-238 4.50e-16

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 75.17  E-value: 4.50e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQMSEAEVG-------VFVQR 113
Cdd:PLN02888   19 GIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIIL-TGSGRAFCSGVDLTAAEEVFKGDVKdvetdpvAQMER 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 114 LR----GLMN--------------DI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTEAHV 153
Cdd:PLN02888   98 CRkpiiGAINgfaitagfeialacDIlvasrgakfidthakfgifpswGLSQKLSRIIGANRAREVSLTAMPLTAETAER 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 154 LGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIE---GMCYAQNIpTRDRLEGMAA 230
Cdd:PLN02888  178 WGLVNHVVEESE----LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEkerAHDYYNGM-TKEQFQKMQE 252

                  ....*...
gi 1370453736 231 FREKRTPK 238
Cdd:PLN02888  253 FIAGRSSK 260
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
45-237 1.06e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 71.10  E-value: 1.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  45 ILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK--------------------------- 97
Cdd:PRK09076   16 LTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNlfadgdkavaremarrfgeafealsaf 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  98 -----------------------------EREQMSEAEVGVfvqrlrGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSG 148
Cdd:PRK09076   95 rgvsiaaingyamggglecalacdiriaeEQAQMALPEASV------GLLPCAGGTQNLPWLVGEGWAKRMILCGERVDA 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 149 TEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGM 228
Cdd:PRK09076  169 ATALRIGLVEEVVEKGE----AREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGV 244

                  ....*....
gi 1370453736 229 AAFREKRTP 237
Cdd:PRK09076  245 NAFLEKRAP 253
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
39-242 3.10e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 69.94  E-value: 3.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGADLKERE-----------QMSEAEV 107
Cdd:PRK08140   11 EAGVATLTLNRPDKLNSFTREMHRELREALDQV-EDDGARALLLTGAGRG-FCAGQDLADRDvtpggampdlgESIETFY 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 108 GVFVQRLR-------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGR 144
Cdd:PRK08140   89 NPLVRRLRalplpviaavngvaagaganlalacdivlaarsasfiqafvkiGLVPDSGGTWFLPRLVGMARALGLALLGE 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 145 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDR 224
Cdd:PRK08140  169 KLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLAT----QPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADY 244
                         250
                  ....*....|....*...
gi 1370453736 225 LEGMAAFREKRTPKFVGK 242
Cdd:PRK08140  245 AEGVSAFLEKRAPRFTGR 262
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
39-242 3.68e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 69.95  E-value: 3.68e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKEREQM---SEAEVGVFVQRLR 115
Cdd:PRK05995   11 RGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVL-AGAGKAFCAGADLNWMKKMagySDDENRADARRLA 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 116 GLMNDI-----------------GGT-----------------------------QRLP---RCLGVALAKELIFTGRRL 146
Cdd:PRK05995   90 DMLRAIyrcpkpviarvhgdayaGGMglvaacdiavaadhavfclsevrlglipaTISPyviRAMGERAARRYFLTAERF 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 147 SGTEAHVLGLVNHAVAQnEEGDAAYQrarALAQEILPQAPIAVRLGKVAIDrgtevDIAsGMAIEGMCYAQnipTRDRL- 225
Cdd:PRK05995  170 DAAEALRLGLVHEVVPA-EALDAKVD---ELLAALVANSPQAVRAGKRLVR-----DVA-GRPIDAALIAD---TASRIa 236
                         250       260
                  ....*....|....*....|....*.
gi 1370453736 226 ---------EGMAAFREKRTPKFVGK 242
Cdd:PRK05995  237 lirateearEGVAAFLEKRKPAWRGR 262
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
39-185 6.79e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 68.77  E-value: 6.79e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK--------------------E 98
Cdd:PRK08259   10 NGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVL-WGAGGTFCAGADLKavgtgrgnrlhpsgdgpmgpS 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  99 REQMS-----------------------------EAEVGVFVQRLRGLMNDiGGTQRLPRCLGVALAKELIFTGRRLSGT 149
Cdd:PRK08259   89 RMRLSkpviaavsgyavagglelalwcdlrvaeeDAVFGVFCRRWGVPLID-GGTVRLPRLIGHSRAMDLILTGRPVDAD 167
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1370453736 150 EAHVLGLVNHAVAQNEegdaAYQRARALAQEI--LPQA 185
Cdd:PRK08259  168 EALAIGLANRVVPKGQ----ARAAAEELAAELaaFPQT 201
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
34-239 2.63e-13

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 67.35  E-value: 2.63e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  34 ALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMS---------- 103
Cdd:PRK07327   14 RFDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIR-GEGKAFSAGGDLALVEEMAddfevrarvw 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 104 -EAEVGVF---------VQRLRG----------LMNDIG----------GTQRL------------PRCLGVALAKELIF 141
Cdd:PRK07327   93 rEARDLVYnvincdkpiVSAIHGpavgaglvaaLLADISiaakdariidGHTRLgvaagdhaaivwPLLCGMAKAKYYLL 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 142 TGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQeilpQAPIAVRLGKVAID---RGTEVDIASGMAIEGMCYAqn 218
Cdd:PRK07327  173 LCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAA----GSQTAIRWTKYALNnwlRMAGPTFDTSLALEFMGFS-- 246
                         250       260
                  ....*....|....*....|.
gi 1370453736 219 ipTRDRLEGMAAFREKRTPKF 239
Cdd:PRK07327  247 --GPDVREGLASLREKRAPDF 265
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
39-176 2.81e-13

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 68.77  E-value: 2.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLK---------EREQMSEAEVG 108
Cdd:PRK11154   13 EDNIAVITIDVPGEKmNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINmlaacktaqEAEALARQGQQ 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 109 VFVQ---------------------------RLR-----------------GLMNDIGGTQRLPRCLGVALAKELIFTGR 144
Cdd:PRK11154   93 LFAEiealpipvvaaihgaclggglelalacHYRvctddpktvlglpevqlGLLPGSGGTQRLPRLIGVSTALDMILTGK 172
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1370453736 145 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARA 176
Cdd:PRK11154  173 QLRAKQALKLGLVDDVVPHSILLEVAVELAKK 204
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
39-242 3.60e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 67.34  E-value: 3.60e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADL---------KEREQMSE----- 104
Cdd:PRK08260   11 ADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIV-TGAGRAFCAGADLsaggntfdlDAPRTPVEadeed 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 105 ---------------------------------AEVGV--------------------FVQRLRGLMNDIGGTQRLPRCL 131
Cdd:PRK08260   90 radpsddgvrdgggrvtlrifdslkpviaavngPAVGVgatmtlamdirlastaarfgFVFGRRGIVPEAASSWFLPRLV 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 132 GVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEilpQAPIAVRLGKVAIDRGTEVDI-ASGMAI 210
Cdd:PRK08260  170 GLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADN---TSPVSVALTRQMMWRMAGADHpMEAHRV 246
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1370453736 211 EGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK 242
Cdd:PRK08260  247 DSRAIYSRGRSGDGKEGVSSFLEKRPAVFPGK 278
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
39-238 6.10e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 66.20  E-value: 6.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQMSEAEVGVFVQRL---- 114
Cdd:PRK08150    9 DGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVL---HGEGDHFCAGLDLSELRERDAGEGMHHSRRWhrvf 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 115 ----------------------------------------------RGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSG 148
Cdd:PRK08150   86 dkiqygrvpviaalhgavvggglelasaahirvadestyfalpegqRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDA 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 149 TEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMC--YAQNIP-TRDRL 225
Cdd:PRK08150  166 QEGERLGLAQYLVPAGE----ALDKAMELARRIAQNAPLTNFAVLNALPRIADMSADDGLFVESLMaaVAQSAPeAKERL 241
                         250
                  ....*....|...
gi 1370453736 226 egmAAFREKRTPK 238
Cdd:PRK08150  242 ---RAFLEKKAAK 251
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
39-242 1.24e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 65.44  E-value: 1.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRSGVKGvFCAGAD----LKEREQMSEAEVGVFVQRL 114
Cdd:PRK07659   13 EGRVATIMLNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNGRG-FSAGGDikmmLSSNDESKFDGVMNTISEI 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 115 R-----------------------------------------------GLMNDIGGTQRLPRCLGVALAKELIFTGRRLS 147
Cdd:PRK07659   91 VvtlytmpkltisaihgpaaglglsialtadyviadisaklamnfigiGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLS 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 148 GTEAHVLGLVNhAVAQNEEGDAAYQRARALAQEILpQAPIAVRLGKVAIDRGTEVDIasgMAIEGMCYAQNIPTRDRLEG 227
Cdd:PRK07659  171 ATEALDLGLID-EVIGGDFQTAAKQKISEWLQKPL-KAMIETKQIYCELNRSQLEQV---LQLEKRAQYAMRQTADHKEG 245
                         250
                  ....*....|....*
gi 1370453736 228 MAAFREKRTPKFVGK 242
Cdd:PRK07659  246 IRAFLEKRLPVFKGE 260
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
39-241 2.94e-12

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 64.60  E-value: 2.94e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALgnVFVS--ELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE----REQMSEAEV----- 107
Cdd:PRK08258   24 DDGVATITLNRPERKNPL--TFESyaELRDLFRELVYADDVKAVVLT-GAGGNFCSGGDVHEiigpLTKMDMPELlaftr 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 108 --GVFVQRLR-------------------------------------------GLMN-DIGGTQRLPRCLGVALAKELIF 141
Cdd:PRK08258  101 mtGDLVKAMRacpqpiiaavdgvcagagailamasdlrlgtpsaktaflftrvGLAGaDMGACALLPRIIGQGRASELLY 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 142 TGRRLSGTEAHVLGLVNHAVaqneEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRgtEVDIASGMAIEGMCYAQNI-- 219
Cdd:PRK08258  181 TGRSMSAEEGERWGFFNRLV----EPEELLAEAQALARRLAAGPTFAHGMTKTMLHQ--EWDMGLEEAIEAEAQAQAIcm 254
                         250       260
                  ....*....|....*....|..
gi 1370453736 220 PTRDRLEGMAAFREKRTPKFVG 241
Cdd:PRK08258  255 QTEDFRRAYEAFVAKRKPVFEG 276
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
38-238 2.53e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 61.90  E-value: 2.53e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKER------------------ 99
Cdd:PRK08290   10 VAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKH-FSAGHDLGSGtpgrdrdpgpdqhptlww 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 100 --------EQMSEAEVGVFVQ---RLR-----------------GLM-----------ND-----------IGGTQRL-- 127
Cdd:PRK08290   89 dgatkpgvEQRYAREWEVYLGmcrRWRdlpkptiaqvqgaciagGLMlawvcdlivasDDaffsdpvvrmgIPGVEYFah 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 128 PRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEegdaAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVD---- 203
Cdd:PRK08290  169 PWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDE----LEAETLELARRIAAMPPFGLRLTKRAVNQTLDAQgfra 244
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1370453736 204 -IASGMAIEGMCYAQN------IPTRDRLEGMAAFREKRTPK 238
Cdd:PRK08290  245 aLDAVFDLHQLGHAHNaevggdRLGGADARGMADARKAAAAK 286
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
115-242 5.31e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 60.74  E-value: 5.31e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 115 RGLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEgdaaYQRARALAQEILPQAPIAVRL--- 191
Cdd:PRK06563  132 RGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEALRLGLVQEVVPPGEQ----LERAIELAERIARAAPLGVQAtla 207
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370453736 192 -GKVAIDRGTEVDIASGMAIegmcYAQNIPTRDRLEGMAAFREKRTPKFVGK 242
Cdd:PRK06563  208 sARAAVREGEAAAAAQLPPE----LRPLFTSEDAKEGVQAFLERRPARFKGR 255
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
39-238 6.75e-10

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 57.71  E-value: 6.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKE--REQMSEAEVGV------- 109
Cdd:PRK09120   15 EDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLT-GAGDAWSAGMDLKEyfRETDAQPEILQerirrea 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 110 --FVQRLR-------GLMNDI---GGTQRLPRC-LGVAlAKELIF---------------------------------TG 143
Cdd:PRK09120   94 ygWWRRLRwyqkptiAMVNGWcfgGGFSPLVACdLAIA-ADEAQFglseinwgippgggvskamadtvghrdalyyimTG 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 144 RRLSGTEAHVLGLVNHAV--AQNEEgdaayqRARALAQEILPQAPIAVRLGKVAIDRGTEvdiasgmaiegMCYAQNI-- 219
Cdd:PRK09120  173 ETFTGRKAAEMGLVNESVplAQLRA------RTRELAAKLLEKNPVVLRAAKDGFKRVRE-----------LTWDQAEdy 235
                         250       260       270
                  ....*....|....*....|....*....|.
gi 1370453736 220 ------------PTRDRLEGMAAFREKRTPK 238
Cdd:PRK09120  236 lyakleqansldPEGGREEGLKQFLDDKSYK 266
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
41-239 9.98e-10

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 57.21  E-value: 9.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ---MSEAEVGVF----VQR 113
Cdd:PRK07396   22 GIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYggyVDDDGVPRLnvldLQR 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 114 L-RGLMN---------DIGGTQ----------------------------------RLPRCLGVALAKELIFTGRRLSGT 149
Cdd:PRK07396  102 LiRTCPKpviamvagyAIGGGHvlhlvcdltiaadnaifgqtgpkvgsfdggygasYLARIVGQKKAREIWFLCRQYDAQ 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 150 EAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDrgTEVDIASGMA-IEG---MCYAQnipTRDRL 225
Cdd:PRK07396  182 EALDMGLVNTVVPLADLEKETVRWCR----EMLQNSPMALRCLKAALN--ADCDGQAGLQeLAGnatMLFYM---TEEAQ 252
                         250
                  ....*....|....
gi 1370453736 226 EGMAAFREKRTPKF 239
Cdd:PRK07396  253 EGRNAFNEKRQPDF 266
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
41-241 6.36e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 54.78  E-value: 6.36e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLKE-REQMSE--------------- 104
Cdd:PRK06072    9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIV-TGEGRAFCVGADLSEfAPDFAIdlretfypiireirf 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 105 -------AEVGV----------------------FV---QRLrGLMNDIGGTQRLPRcLGVALAKELIFTGRRLSGTEAH 152
Cdd:PRK06072   88 sdkiyisAINGVtagacigialstdfkfasrdvkFVtafQRL-GLASDTGVAYFLLK-LTGQRFYEILVLGGEFTAEEAE 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 153 VLGLVnhavaqnEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPTRDRLEGMAAFR 232
Cdd:PRK06072  166 RWGLL-------KISEDPLSDAEEMANRISNGPFQSYIAAKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGISSFK 238

                  ....*....
gi 1370453736 233 EKRTPKFVG 241
Cdd:PRK06072  239 EKREPKFKG 247
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
41-239 1.13e-08

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 54.44  E-value: 1.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLF-----RSGVKGVFCAGADLKEREQ---MSEAEVGVF-- 110
Cdd:COG0447    27 GIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLtgngpSKDGGWAFCSGGDQRVRGRggyVYEDGVGRLni 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 111 --VQRLRGLMN--------------------------------------DIG------GTQRLPRCLGVALAKELIFTGR 144
Cdd:COG0447   107 leVQRLIRFMPkpviamvagwaiggghvlhvvcdltiasenarfgqtgpDVGsfdagyGSAYLARQVGQKKAREIWFLCR 186
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 145 RLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVAIDRGTEvdiasGMAieG----------MC 214
Cdd:COG0447   187 QYSAQEALEMGLVNKVVPHAELEEEAVEWAR----EILEKSPTAIRMLKAAFNADDD-----GLA--GqqefageatrLA 255
                         250       260
                  ....*....|....*....|....*
gi 1370453736 215 YAqnipTRDRLEGMAAFREKRTPKF 239
Cdd:COG0447   256 YM----TDEAQEGRDAFLEKRKPDF 276
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
36-197 1.50e-08

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 53.30  E-value: 1.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  36 AGPDQGITEILMNRPSArNALGNVFVSELLETLAQL-REDRQVRVLLFrsGVKGVFCAGADLKEREQMS--EAEVGVFVQ 112
Cdd:PRK05869   12 GSQDAGLATLLLSRPPT-NALTRQVYREIVAAANELgRRDDVAAVILY--GGHEIFSAGDDMPELRTLSaqEADTAARVR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 113 R------------------------------------------------LRGLMNDIGGTQRLPRCLGVALAKELIFTGR 144
Cdd:PRK05869   89 QqavdavaaipkptvaaitgyalgagltlalaadwrvsgdnvkfgateiLAGLAPSGDGMARLTRAAGPSRAKELVFSGR 168
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1370453736 145 RLSGTEAHVLGLVNHAVAQneegDAAYQRARALAQEILPQAPIAVRLGKVAID 197
Cdd:PRK05869  169 FFDAEEALALGLIDEMVAP----DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
105-242 1.57e-08

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 53.58  E-value: 1.57e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 105 AEVGVFVQRLR--GLMNDIGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAqeil 182
Cdd:PRK05981  131 ARSAYFLQAFRriGLVPDGGSTWLLPRLVGKARAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELA---- 206
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370453736 183 pQAPiAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIP--TRDRLEGMAAFREKRTPKFVGK 242
Cdd:PRK05981  207 -NGP-TVALGLIRKLYWDSPENDFEEQLNLEREAQRIAgkTEDFKEGVGAFLQKRPAQFKGR 266
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
27-170 1.82e-08

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 54.48  E-value: 1.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  27 GSEIQVRALagpDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGvKGVFCAGADLKERE---QMS 103
Cdd:PRK11730    5 GKTLQVDWL---EDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSA-KDAFIVGADITEFLslfAAP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 104 EAEV--------GVFVQ-----------------------------RLR-------------GLMNDIGGTQRLPRCLGV 133
Cdd:PRK11730   81 EEELsqwlhfanSIFNRledlpvptvaaingyalgggcecvlatdyRVAspdariglpetklGIMPGFGGTVRLPRLIGA 160
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1370453736 134 ALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAA 170
Cdd:PRK11730  161 DNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAA 197
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
34-235 2.02e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 53.50  E-value: 2.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  34 ALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQR 113
Cdd:PRK06143    9 GVTRDDRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 114 LRGLMNDI-----------------GGTQ--------------------------------RLPRCLGVALAKELIFTGR 144
Cdd:PRK06143   89 LRDLCDAVrhfpvpviaripgwclgGGLElaaacdlriaahdaqfgmpevrvgipsvihaaLLPRLIGWARTRWLLLTGE 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 145 RLSGTEAHVLGLVnHAVAQNEEGDAAYQRaraLAQEILPQAPIAVRLGKVAI----DRGTEVDIASGMAIEGMCYAQNIP 220
Cdd:PRK06143  169 TIDAAQALAWGLV-DRVVPLAELDAAVER---LAASLAGCGPQALRQQKRLLreweDMPLDVAIDDSVAEFGAAFLTGEP 244
                         250
                  ....*....|....*
gi 1370453736 221 TRDrlegMAAFREKR 235
Cdd:PRK06143  245 QRH----MAAFLNRK 255
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
35-242 2.80e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 53.14  E-value: 2.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  35 LAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADLK-EREQMSE------AEV 107
Cdd:PRK07468    8 IAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVL-TGAGKSFCAGGDLGwMRAQMTAdratriEEA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 108 GVFVQRLRGLmNDI--------------GGTQRLPRC--------------------------------LGVALAKELIF 141
Cdd:PRK07468   87 RRLAMMLKAL-NDLpkpligriqgqafgGGVGLISVCdvaiavsgarfgltetrlglipatispyvvarMGEANARRVFM 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 142 TGRRLSGTEAHVLGLVNHAVAQnEEGDAAYQRaralaqEILPQ---APIAV-RLGKVAIDRGTEVDIAS-GMAIEGMcyA 216
Cdd:PRK07468  166 SARLFDAEEAVRLGLLSRVVPA-ERLDAAVEA------EVTPYlscAPGAVaAAKALVRALGAPIDEAViDATIEAL--A 236
                         250       260
                  ....*....|....*....|....*.
gi 1370453736 217 QNIPTRDRLEGMAAFREKRTPKFVGK 242
Cdd:PRK07468  237 DTWETEEAREGIAAFFDKRAPAWRGG 262
PLN02921 PLN02921
naphthoate synthase
39-239 1.53e-07

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 51.33  E-value: 1.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ-----------MSEAEV 107
Cdd:PLN02921   74 GEGIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKdgyvgpddagrLNVLDL 153
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 108 GVFVQRL--------RG----------LMNDIG----------------------GTQRLPRCLGVALAKELIFTGRRLS 147
Cdd:PLN02921  154 QIQIRRLpkpviamvAGyavggghilhMVCDLTiaadnavfgqtgpkvgsfdagyGSSIMARLVGQKKAREMWFLARFYT 233
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 148 GTEAHVLGLVNHAV--AQNEEGDAAYQRaralaqEILPQAPIAVRLGKVAIDRGTevDIASGmaIEGMcyAQNIP----- 220
Cdd:PLN02921  234 ASEALKMGLVNTVVplDELEGETVKWCR------EILRNSPTAIRVLKSALNAAD--DGHAG--LQEL--GGNATllfyg 301
                         250
                  ....*....|....*....
gi 1370453736 221 TRDRLEGMAAFREKRTPKF 239
Cdd:PLN02921  302 SEEGNEGRTAYLEGRAPDF 320
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
39-242 1.55e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 50.79  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLrEDRQVRVLLFRsGVKGVFCAGADLKEREQMSEaevgvFVQRLRGLM 118
Cdd:PRK07854    7 DGQVLTIELQRPERRNALNAELCEELREAVRKA-VDESARAIVLT-GQGTVFCAGADLSGDVYADD-----FPDALIEML 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 119 NDI-----------------GGTQ---------------------------------RLPRCLGVALAKELIFTGRRLSG 148
Cdd:PRK07854   80 HAIdaapvpviaaingpaigAGLQlamacdlrvvapeayfqfpvakygialdnwtirRLSSLVGGGRARAMLLGAEKLTA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 149 TEAHVLGLVNhavaqnEEGDAAyqRARALAQEILPQAPIAVRLGKVAI-DRGTEVDIASG-MAIEGMCYAqnipTRDRLE 226
Cdd:PRK07854  160 EQALATGMAN------RIGTLA--DAQAWAAEIAGLAPLALQHAKRVLnDDGAIEEAWPAhKELFDKAWA----SQDAIE 227
                         250
                  ....*....|....*.
gi 1370453736 227 GMAAFREKRTPKFVGK 242
Cdd:PRK07854  228 AQVARIEKRPPKFQGA 243
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
39-239 2.40e-07

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 50.41  E-value: 2.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFR----SGVKG--VFCAGADLKER------------- 99
Cdd:PRK08321   32 DQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTgngpSPKDGgwAFCSGGDQRIRgrdgyqyaegdea 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 100 EQMSEAEVGVF----VQRLRGLM---------------------------------------NDIG------GTQRLPRC 130
Cdd:PRK08321  112 DTVDPARAGRLhileVQRLIRFMpkvviavvpgwaaggghslhvvcdltlasreharfkqtdADVGsfdggyGSAYLARQ 191
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 131 LGVALAKELIFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARalaqEILPQAPIAVRLGKVA---IDRG-TEVDIAS 206
Cdd:PRK08321  192 VGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAR----EINGKSPTAMRMLKYAfnlTDDGlVGQQLFA 267
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1370453736 207 GMAIEgMCYAqnipTRDRLEGMAAFREKRTPKF 239
Cdd:PRK08321  268 GEATR-LAYM----TDEAQEGRDAFLEKRDPDW 295
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
45-161 2.64e-07

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 50.55  E-value: 2.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-REQMSEAE---------------- 106
Cdd:pfam16113   4 ITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGaGERA-FCAGGDVRAlYEAAKAGGgeagrdffreeyrlny 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 107 ---------------------VGVFVQ-RLR---------------GLMNDIGGTQRLPRC---LGVALAkeliFTGRRL 146
Cdd:pfam16113  83 liatypkpyvalmdgivmgggVGLSVHgSFRvvtertrfampetaiGLFPDVGGSYFLSRLpgeLGLYLA----LTGARL 158
                         170
                  ....*....|....*
gi 1370453736 147 SGTEAHVLGLVNHAV 161
Cdd:pfam16113 159 NGADALAAGLATHYV 173
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
38-179 3.40e-07

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 49.58  E-value: 3.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLK-----EREQMSEAEVGVFVQ 112
Cdd:PRK07110   11 VEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILT-GYPNYFATGGTQEgllslQTGKGTFTEANLYSL 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 113 RLR--------------------GLMNDI----------------------GGTQRLPRCLGVALAKELIFTGRRLSGTE 150
Cdd:PRK07110   90 ALNcpipviaamqghaiggglvlGLYADIvvlsresvytanfmkygftpgmGATAILPEKLGLALGQEMLLTARYYRGAE 169
                         170       180
                  ....*....|....*....|....*....
gi 1370453736 151 AHVLGLVNHAVAQNEEGDAAYQRARALAQ 179
Cdd:PRK07110  170 LKKRGVPFPVLPRAEVLEKALELARSLAE 198
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
37-196 6.92e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 48.81  E-value: 6.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  37 GPDQGITEILMNRPSArNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKEREQMS------------- 103
Cdd:PRK07938    7 TPEPGIAEVTVDYPPV-NALPSAGWFALADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQATPgftalidanrgcf 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 104 -------EAEVGVFV-------------------------------QRLRGLMndiGGTQRLPRCLGVALAKELIFTGRR 145
Cdd:PRK07938   85 aafravyECAVPVIAavhgfclgggiglvgnadvivasddatfglpEVDRGAL---GAATHLQRLVPQHLMRALFFTAAT 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370453736 146 LSGTEAHVLGLVnHAVAQNEEGDAAyqrARALAQEILPQAPIAVRLGKVAI 196
Cdd:PRK07938  162 ITAAELHHFGSV-EEVVPRDQLDEA---ALEVARKIAAKDTRVIRAAKEAL 208
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
41-198 9.01e-07

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 49.45  E-value: 9.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  41 GITEILMNRPSAR-NALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGAD---------LKEREQMS-EAEVGV 109
Cdd:TIGR02441  22 DVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADiqmiaacktAQEVTQLSqEGQEMF 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 110 F-VQR------------------------------------------LRGLMNDIGGTQRLPRCLGVALAKELIFTGRRL 146
Cdd:TIGR02441 102 ErIEKsqkpivaaisgsclggglelalachyriatkdrktllglpevMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKI 181
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1370453736 147 SGTEAHVLGLVNHAVAQNEEG-DAAYQRARALAQEILPQAPIAVRLGKVAIDR 198
Cdd:TIGR02441 182 RADRAKKMGIVDQLVDPLGPGlKPAEENTIEYLEEVAVKFAQGLANGKLSINR 234
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
39-117 2.36e-06

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 47.37  E-value: 2.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVR-VLLFRSGvkGVFCAGADLKEREQMSEAEVGVFVQRLRGL 117
Cdd:PRK07827   13 DGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRaVVLTHTG--GTFCAGADLSEAGGGGGDPYDAAVARAREM 90
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
38-240 1.12e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 45.21  E-value: 1.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGAD-------------------LKE 98
Cdd:PRK05864   16 PRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSSGADhksagvvphvegltrptyaLRS 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  99 REQMSE------------------------------AEVGVFVQ----RLRGLMN-----DIGGTQRLPRCLGVALAKEL 139
Cdd:PRK05864   95 MELLDDvilalrrlhqpviaavngpaiggglclalaADIRVASSsayfRAAGINNgltasELGLSYLLPRAIGSSRAFEI 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 140 IFTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTevdIASGMAIEGMcyAQ-- 217
Cdd:PRK05864  175 MLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGLDAAS---LEAHMQAEGL--GQlf 249
                         250       260
                  ....*....|....*....|....
gi 1370453736 218 -NIPTRDRLEGMAAFREKRTPKFV 240
Cdd:PRK05864  250 vRLLTANFEEAVAARAEKRPPVFT 273
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
45-97 3.07e-05

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 44.41  E-value: 3.07e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1370453736  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLK 97
Cdd:PLN02874   24 ITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIK-GAGRAFSAGGDLK 75
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
38-108 1.41e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 41.95  E-value: 1.41e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370453736  38 PDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGvFCAGADLKE-REQMSEAEVG 108
Cdd:PRK08272   16 VTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKG-FCAGYDLSAyAEGSSSGGGG 86
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
40-104 1.57e-04

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 41.72  E-value: 1.57e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370453736  40 QGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRsGVKGVFCAGADLKEREQMSE 104
Cdd:PRK05674   14 RGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLR-GRGRHFSAGADLAWMQQSAD 77
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
45-165 1.88e-04

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 41.73  E-value: 1.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  45 ILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRS-GVKGvFCAGADLKE-----REQMSEAEVGVFVQ------ 112
Cdd:PRK05617   16 ITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGaGERG-FCAGGDIRAlyeaaRAGDPLAADRFFREeyrlna 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736 113 ----------------------------RLR---------------GLMNDIGGTQRLPRCLGvALAKELIFTGRRLSGT 149
Cdd:PRK05617   95 liarypkpyialmdgivmgggvgisahgSHRivtertkmampetgiGFFPDVGGTYFLSRAPG-ALGTYLALTGARISAA 173
                         170
                  ....*....|....*.
gi 1370453736 150 EAHVLGLVNHAVAQNE 165
Cdd:PRK05617  174 DALYAGLADHFVPSAD 189
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
39-101 2.55e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 41.21  E-value: 2.55e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLlfrSGVKGVFCAGADLKEREQ 101
Cdd:PRK07112   11 QGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATIVVL---EGLPEVFCFGADFSAIAE 70
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
39-96 9.46e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 39.32  E-value: 9.46e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFrSGVKGVFCAGADL 96
Cdd:PRK05870   10 DDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVV-TGAGKAFCAGADL 66
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
39-129 1.58e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 38.95  E-value: 1.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370453736  39 DQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKgVFCAGADLKEREQMSEAEVGVFVQRLRGLM 118
Cdd:PRK07260    9 EDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELV 87
                          90
                  ....*....|..
gi 1370453736 119 NDIG-GTQRLPR 129
Cdd:PRK07260   88 NEISfAIKQLPK 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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