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Conserved domains on  [gi|1370461942|ref|XP_024304751|]
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nucleosome assembly protein 1-like 1 isoform X2 [Homo sapiens]

Protein Classification

NAP domain-containing protein( domain architecture ID 10469758)

NAP domain-containing protein similar to Saccharomyces cerevisiae nucleosome assembly protein (NAP) and Homo sapiens protein SET

CATH:  3.30.1120.90
Gene Ontology:  GO:0042393|GO:0003682|GO:0006334
SCOP:  4003454

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
NAP pfam00956
Nucleosome assembly protein (NAP); NAP proteins are involved in moving histones into the ...
13-280 6.06e-92

Nucleosome assembly protein (NAP); NAP proteins are involved in moving histones into the nucleus, nucleosome assembly and chromatin fluidity. They affect the transcription of many genes.


:

Pssm-ID: 460010  Cd Length: 203  Bit Score: 272.51  E-value: 6.06e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  13 RRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFdkrfeiinaiyepteeecewkpdeedeiseelkekakiede 92
Cdd:pfam00956   1 RRVNALKKLQKEHEKLEAEFQEEVHELEKKYAALYQPLY----------------------------------------- 39
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  93 kkdeekedpkgipefwltvfKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAgqPMSFVLEFHFEPNEYFTNEVLTKTYRM 172
Cdd:pfam00956  40 --------------------KNLPLLSEMITERDEPALKHLKDIKIEYPLD--EPGFTLEFHFAPNPYFTNTVLTKTYYY 97
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942 173 RSEPDdsdpfsfdGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDL--- 249
Cdd:pfam00956  98 QDEPD--------GPEIIKAEGTEIDWKEGKNVTVKTVKKKQRNKGTGQTRTVTKTVPTESFFNFFSPPEVPEDEDEdde 169
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1370461942 250 -DDDAEAILAADFEIGHFLRERIIPRSVLYFT 280
Cdd:pfam00956 170 eDEELEERLELDYEIGEDIKDKIIPRAVLYFT 201
 
Name Accession Description Interval E-value
NAP pfam00956
Nucleosome assembly protein (NAP); NAP proteins are involved in moving histones into the ...
13-280 6.06e-92

Nucleosome assembly protein (NAP); NAP proteins are involved in moving histones into the nucleus, nucleosome assembly and chromatin fluidity. They affect the transcription of many genes.


Pssm-ID: 460010  Cd Length: 203  Bit Score: 272.51  E-value: 6.06e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  13 RRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFdkrfeiinaiyepteeecewkpdeedeiseelkekakiede 92
Cdd:pfam00956   1 RRVNALKKLQKEHEKLEAEFQEEVHELEKKYAALYQPLY----------------------------------------- 39
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  93 kkdeekedpkgipefwltvfKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAgqPMSFVLEFHFEPNEYFTNEVLTKTYRM 172
Cdd:pfam00956  40 --------------------KNLPLLSEMITERDEPALKHLKDIKIEYPLD--EPGFTLEFHFAPNPYFTNTVLTKTYYY 97
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942 173 RSEPDdsdpfsfdGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDL--- 249
Cdd:pfam00956  98 QDEPD--------GPEIIKAEGTEIDWKEGKNVTVKTVKKKQRNKGTGQTRTVTKTVPTESFFNFFSPPEVPEDEDEdde 169
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1370461942 250 -DDDAEAILAADFEIGHFLRERIIPRSVLYFT 280
Cdd:pfam00956 170 eDEELEERLELDYEIGEDIKDKIIPRAVLYFT 201
PTZ00007 PTZ00007
(NAP-L) nucleosome assembly protein -L; Provisional
12-280 7.82e-51

(NAP-L) nucleosome assembly protein -L; Provisional


Pssm-ID: 240226 [Multi-domain]  Cd Length: 337  Bit Score: 171.51  E-value: 7.82e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  12 KRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAiyePTEEEcewkpdeedeiseelkekakied 91
Cdd:PTZ00007   40 RETLKKLQLLQKEFDDLEVEYNAELRKLRSKYEDLYNPIYDKRKEALVQ---NGGAE----------------------- 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  92 ekkdeekEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYR 171
Cdd:PTZ00007   94 -------IGTPGLPQFWLTAMKNNNTLGSAIEEHDEPILSYLSDISCEYTEPNKQEGFILVFTFAPNPFFSNTVLTKTYH 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942 172 MRSEPDDsdpfsfDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDLDD 251
Cdd:PTZ00007  167 MKVLDGD------DEPLLSNTVATEIDWKQGKDVTKKVVTKKQRHKKTKETRTVTETVDRESFFNFFTSHEVPSDEELEK 240
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1370461942 252 -------DAEAILAADFEIGHFLRERIIPRSVLYFT 280
Cdd:PTZ00007  241 mskheiaELEMIVETDYEIGITIRDKLIPYAVYWFL 276
 
Name Accession Description Interval E-value
NAP pfam00956
Nucleosome assembly protein (NAP); NAP proteins are involved in moving histones into the ...
13-280 6.06e-92

Nucleosome assembly protein (NAP); NAP proteins are involved in moving histones into the nucleus, nucleosome assembly and chromatin fluidity. They affect the transcription of many genes.


Pssm-ID: 460010  Cd Length: 203  Bit Score: 272.51  E-value: 6.06e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  13 RRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFdkrfeiinaiyepteeecewkpdeedeiseelkekakiede 92
Cdd:pfam00956   1 RRVNALKKLQKEHEKLEAEFQEEVHELEKKYAALYQPLY----------------------------------------- 39
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  93 kkdeekedpkgipefwltvfKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAgqPMSFVLEFHFEPNEYFTNEVLTKTYRM 172
Cdd:pfam00956  40 --------------------KNLPLLSEMITERDEPALKHLKDIKIEYPLD--EPGFTLEFHFAPNPYFTNTVLTKTYYY 97
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942 173 RSEPDdsdpfsfdGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDL--- 249
Cdd:pfam00956  98 QDEPD--------GPEIIKAEGTEIDWKEGKNVTVKTVKKKQRNKGTGQTRTVTKTVPTESFFNFFSPPEVPEDEDEdde 169
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1370461942 250 -DDDAEAILAADFEIGHFLRERIIPRSVLYFT 280
Cdd:pfam00956 170 eDEELEERLELDYEIGEDIKDKIIPRAVLYFT 201
PTZ00007 PTZ00007
(NAP-L) nucleosome assembly protein -L; Provisional
12-280 7.82e-51

(NAP-L) nucleosome assembly protein -L; Provisional


Pssm-ID: 240226 [Multi-domain]  Cd Length: 337  Bit Score: 171.51  E-value: 7.82e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  12 KRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAiyePTEEEcewkpdeedeiseelkekakied 91
Cdd:PTZ00007   40 RETLKKLQLLQKEFDDLEVEYNAELRKLRSKYEDLYNPIYDKRKEALVQ---NGGAE----------------------- 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942  92 ekkdeekEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYR 171
Cdd:PTZ00007   94 -------IGTPGLPQFWLTAMKNNNTLGSAIEEHDEPILSYLSDISCEYTEPNKQEGFILVFTFAPNPFFSNTVLTKTYH 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370461942 172 MRSEPDDsdpfsfDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDLDD 251
Cdd:PTZ00007  167 MKVLDGD------DEPLLSNTVATEIDWKQGKDVTKKVVTKKQRHKKTKETRTVTETVDRESFFNFFTSHEVPSDEELEK 240
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1370461942 252 -------DAEAILAADFEIGHFLRERIIPRSVLYFT 280
Cdd:PTZ00007  241 mskheiaELEMIVETDYEIGITIRDKLIPYAVYWFL 276
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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