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Conserved domains on  [gi|1370465855|ref|XP_024305555|]
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protein TALPID3 isoform X19 [Homo sapiens]

Protein Classification

TALPID3 domain-containing protein( domain architecture ID 12173090)

TALPID3 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 5-1225 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


:

Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1915.02  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855    5 KAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQE 84
Cdd:pfam15324   22 RAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIKVQSDLEAKVNSVSELLKKLQE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855   85 TDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKY 164
Cdd:pfam15324  102 TDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGSALKAVSLQPSSVTSSRAVEKS 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  165 --SVKPEHPNLGSCNPSLYnTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVSC 242
Cdd:pfam15324  182 gnSSEDESPAVGSASTSHH-TFAPKQAPLAEVRDTQFDRQKSPLETPAPRRFAPVPVSRDAKISKREPPKEEKENMETSS 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  243 HRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNR--------FPSCEELETTKVTMQKSDDVLHDLGQKE 314
Cdd:pfam15324  261 SKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSREsqplepqsFPSSEEPETASVTVQKASDVLQDLGQLK 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  315 KETNSMV-----------------QPKESLSMLKLPDLP------------------QNSVKLQTTNTTRSVLKDAEKIL 359
Cdd:pfam15324  341 KEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSPSVLQSTQPPRSMLKDAEKIL 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  360 RGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQR 439
Cdd:pfam15324  421 RQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEIQDELARKDYEQKRFDQKNRR 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  440 TKKGQNMT--------KDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLPMRGMPASSLQKerKEGLLKATTVIQDEDYM 511
Cdd:pfam15324  501 TAKAQAAKktsvrrqsKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQK--KEGPLKSTTSLQDEDYL 578

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  512 LQVYGKPVYQGHRSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVlPHGDQ 591
Cdd:pfam15324  579 LQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKPVKTDSKMQHSVTA-PHQEQ 657

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  592 QYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKKPNIAIVEMKS 671
Cdd:pfam15324  658 QYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKS 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  672 EKKDPPQLTVQVLPSVDIDSISNSSADV--LSPLSSPKEASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEE 749
Cdd:pfam15324  738 EKKDPPQLTVQVLPSVDIDSVSCSSRDSspSPVLPSPSEASPPLIQTWIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEE 817

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  750 KCDEIPD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ 828
Cdd:pfam15324  818 KEDEIPEfSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVDWVEQEIMARIISGMFPQQA 897

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  829 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVATGVSGDA 908
Cdd:pfam15324  898 QADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIMLGDREAQREPPVAASVPGDL 977

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  909 STNETYLPARVctplPTPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMaFPVKEICAEKG-DDMPAIMLVNtPTVTPT 987
Cdd:pfam15324  978 PTKETLLPTPV----PTPQPTPPCSPPSPLKEPSPVKTPDSSPCVSEHDF-FPVKEIPPEKGaDTGPAVSLVI-TPTVTP 1051

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  988 TTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDfpAQPPPPE 1067
Cdd:pfam15324 1052 IATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVARDEEPESVV--LPASPPE 1129

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855 1068 PVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLNDSLSST 1147
Cdd:pfam15324 1130 PKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSLTVTETETADRPISEGEILFSYGQMLAVRALEEGGLFLPNLNDSLSSS 1209

                         1210      1220      1230      1240      1250      1260      1270
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370465855 1148 LHDAVEMEDDPPSEGQVIRMSHKKFHADAILS-FAKQNQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMG 1225
Cdd:pfam15324 1210 LHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSlLAKMNQGPLSSQQAVYHSEDLENSVGELSEGQRPRLTAAAENVLTG 1288
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 5-1225 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1915.02  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855    5 KAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQE 84
Cdd:pfam15324   22 RAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIKVQSDLEAKVNSVSELLKKLQE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855   85 TDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKY 164
Cdd:pfam15324  102 TDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGSALKAVSLQPSSVTSSRAVEKS 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  165 --SVKPEHPNLGSCNPSLYnTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVSC 242
Cdd:pfam15324  182 gnSSEDESPAVGSASTSHH-TFAPKQAPLAEVRDTQFDRQKSPLETPAPRRFAPVPVSRDAKISKREPPKEEKENMETSS 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  243 HRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNR--------FPSCEELETTKVTMQKSDDVLHDLGQKE 314
Cdd:pfam15324  261 SKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSREsqplepqsFPSSEEPETASVTVQKASDVLQDLGQLK 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  315 KETNSMV-----------------QPKESLSMLKLPDLP------------------QNSVKLQTTNTTRSVLKDAEKIL 359
Cdd:pfam15324  341 KEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSPSVLQSTQPPRSMLKDAEKIL 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  360 RGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQR 439
Cdd:pfam15324  421 RQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEIQDELARKDYEQKRFDQKNRR 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  440 TKKGQNMT--------KDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLPMRGMPASSLQKerKEGLLKATTVIQDEDYM 511
Cdd:pfam15324  501 TAKAQAAKktsvrrqsKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQK--KEGPLKSTTSLQDEDYL 578

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  512 LQVYGKPVYQGHRSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVlPHGDQ 591
Cdd:pfam15324  579 LQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKPVKTDSKMQHSVTA-PHQEQ 657

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  592 QYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKKPNIAIVEMKS 671
Cdd:pfam15324  658 QYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKS 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  672 EKKDPPQLTVQVLPSVDIDSISNSSADV--LSPLSSPKEASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEE 749
Cdd:pfam15324  738 EKKDPPQLTVQVLPSVDIDSVSCSSRDSspSPVLPSPSEASPPLIQTWIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEE 817

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  750 KCDEIPD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ 828
Cdd:pfam15324  818 KEDEIPEfSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVDWVEQEIMARIISGMFPQQA 897

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  829 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVATGVSGDA 908
Cdd:pfam15324  898 QADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIMLGDREAQREPPVAASVPGDL 977

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  909 STNETYLPARVctplPTPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMaFPVKEICAEKG-DDMPAIMLVNtPTVTPT 987
Cdd:pfam15324  978 PTKETLLPTPV----PTPQPTPPCSPPSPLKEPSPVKTPDSSPCVSEHDF-FPVKEIPPEKGaDTGPAVSLVI-TPTVTP 1051

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  988 TTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDfpAQPPPPE 1067
Cdd:pfam15324 1052 IATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVARDEEPESVV--LPASPPE 1129

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855 1068 PVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLNDSLSST 1147
Cdd:pfam15324 1130 PKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSLTVTETETADRPISEGEILFSYGQMLAVRALEEGGLFLPNLNDSLSSS 1209

                         1210      1220      1230      1240      1250      1260      1270
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370465855 1148 LHDAVEMEDDPPSEGQVIRMSHKKFHADAILS-FAKQNQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMG 1225
Cdd:pfam15324 1210 LHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSlLAKMNQGPLSSQQAVYHSEDLENSVGELSEGQRPRLTAAAENVLTG 1288
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 5-1225 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1915.02  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855    5 KAQSMPVFKEVKVHLLEDAGIEKDAVTQETRISPSGIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLSKLQE 84
Cdd:pfam15324   22 RAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIKVQSDLEAKVNSVSELLKKLQE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855   85 TDKHLQRVTEQQTSIQRKQEKLHCHDHEKQMNVFMEQHIRHLEKLQQQQIDIQTHFISAALKTSSFQPVSMPSSRAVEKY 164
Cdd:pfam15324  102 TDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGSALKAVSLQPSSVTSSRAVEKS 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  165 --SVKPEHPNLGSCNPSLYnTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVSRDDELSKRENLLEEKENMEVSC 242
Cdd:pfam15324  182 gnSSEDESPAVGSASTSHH-TFAPKQAPLAEVRDTQFDRQKSPLETPAPRRFAPVPVSRDAKISKREPPKEEKENMETSS 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  243 HRGNVRLLEQILNNNDSLTRKSESSNTTSLTRSKIGWTPEKTNR--------FPSCEELETTKVTMQKSDDVLHDLGQKE 314
Cdd:pfam15324  261 SKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSREsqplepqsFPSSEEPETASVTVQKASDVLQDLGQLK 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  315 KETNSMV-----------------QPKESLSMLKLPDLP------------------QNSVKLQTTNTTRSVLKDAEKIL 359
Cdd:pfam15324  341 KEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSPSVLQSTQPPRSMLKDAEKIL 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  360 RGVQNNKKVLEENLEAIIRAKDGAAMYSLINALSTNREMSEKIRIRKTVDEWIKTISAEIQDELSRTDYEQKRFDQKNQR 439
Cdd:pfam15324  421 RQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEIQDELARKDYEQKRFDQKNRR 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  440 TKKGQNMT--------KDIRTNTQDKTVNKSVIPRKHSQKQIEEHFRNLPMRGMPASSLQKerKEGLLKATTVIQDEDYM 511
Cdd:pfam15324  501 TAKAQAAKktsvrrqsKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQK--KEGPLKSTTSLQDEDYL 578

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  512 LQVYGKPVYQGHRSTLKKGPYLRFNSPSPKSRPQRPKVIERVKGTKVKSIRTQTDFYATKPKKMDSKMKHSVPVlPHGDQ 591
Cdd:pfam15324  579 LQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKPVKTDSKMQHSVTA-PHQEQ 657

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  592 QYLFSPSREMPTFSGTLEGHLIPMAILLGQTQSNSDTMPPAGVIVSKPHPVTVTTSIPPSSRKVETGVKKPNIAIVEMKS 671
Cdd:pfam15324  658 QYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKS 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  672 EKKDPPQLTVQVLPSVDIDSISNSSADV--LSPLSSPKEASLPPVQTWIKTPEIMKVDEEEVKFPGTNFDEIIDVIQEEE 749
Cdd:pfam15324  738 EKKDPPQLTVQVLPSVDIDSVSCSSRDSspSPVLPSPSEASPPLIQTWIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEE 817

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  750 KCDEIPD-SEPILEFNRSVKADSTKYNGPPFPPVASTFQPTADILDKVIERKETLENSLIQWVEQEIMSRIISGLFPVQQ 828
Cdd:pfam15324  818 KEDEIPEfSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVDWVEQEIMARIISGMFPQQA 897

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  829 QIAPSISVSVSETSEPLTSDIVEGTSSGALQLFVDAGVPVNSNVIKHFVNEALAETIAVMLGDREAKKQGPVATGVSGDA 908
Cdd:pfam15324  898 QADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIMLGDREAQREPPVAASVPGDL 977

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  909 STNETYLPARVctplPTPQPTPPCSPSSPAKECVLVKTPDSSPCDSDHDMaFPVKEICAEKG-DDMPAIMLVNtPTVTPT 987
Cdd:pfam15324  978 PTKETLLPTPV----PTPQPTPPCSPPSPLKEPSPVKTPDSSPCVSEHDF-FPVKEIPPEKGaDTGPAVSLVI-TPTVTP 1051

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855  988 TTPPPAAAVFTPTLSDISIDKLKVSSPELPKPWGDGDLPLEEENPNSPQEELHPRAIVMSVAKDEEPESMDfpAQPPPPE 1067
Cdd:pfam15324 1052 IATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVARDEEPESVV--LPASPPE 1129

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370465855 1068 PVPFMPFPAGTKAPSPSQMPGSDSSTLESTLSVTVTETETLDKPISEGEILFSCGQKLAPKILEDIGLYLTNLNDSLSST 1147
Cdd:pfam15324 1130 PKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSLTVTETETADRPISEGEILFSYGQMLAVRALEEGGLFLPNLNDSLSSS 1209

                         1210      1220      1230      1240      1250      1260      1270
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370465855 1148 LHDAVEMEDDPPSEGQVIRMSHKKFHADAILS-FAKQNQESAVSQQAVYHSEDLENSVGELSEGQRPQLTAAAENILMG 1225
Cdd:pfam15324 1210 LHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSlLAKMNQGPLSSQQAVYHSEDLENSVGELSEGQRPRLTAAAENVLTG 1288
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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