NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1370472283|ref|XP_024306721|]
View 

protein DBF4 homolog B isoform X4 [Homo sapiens]

Protein Classification

zf-DBF domain-containing protein( domain architecture ID 10540224)

zf-DBF domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
zf-DBF pfam07535
DBF zinc finger; This domain is predicted to bind metal ions and is often found associated ...
 278-319 2.64e-16

DBF zinc finger; This domain is predicted to bind metal ions and is often found associated with pfam00533 and pfam02178. It was first identified in the Drosophila chiffon gene product, and is associated with initiation of DNA replication.


:

Pssm-ID: 462197  Cd Length: 42  Bit Score: 72.92  E-value: 2.64e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1370472283 278 GYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIAQL 319
Cdd:pfam07535   1 GYCENCRVKYEDLEEHIVSEKHRKFAENDSNFKELDELISKL 42
 
Name Accession Description Interval E-value
zf-DBF pfam07535
DBF zinc finger; This domain is predicted to bind metal ions and is often found associated ...
 278-319 2.64e-16

DBF zinc finger; This domain is predicted to bind metal ions and is often found associated with pfam00533 and pfam02178. It was first identified in the Drosophila chiffon gene product, and is associated with initiation of DNA replication.


Pssm-ID: 462197  Cd Length: 42  Bit Score: 72.92  E-value: 2.64e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1370472283 278 GYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIAQL 319
Cdd:pfam07535   1 GYCENCRVKYEDLEEHIVSEKHRKFAENDSNFKELDELISKL 42
ZnF_DBF smart00586
Zinc finger in DBF-like proteins;
275-319 1.08e-11

Zinc finger in DBF-like proteins;


Pssm-ID: 128854 [Multi-domain]  Cd Length: 49  Bit Score: 59.80  E-value: 1.08e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1370472283  275 RKKGYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIAQL 319
Cdd:smart00586   3 KKPGYCENCREKYDDLETHLLSEKHRRFAENNDNFQALDDLISQL 47
DBF4 COG5067
Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, ...
 262-319 4.90e-05

Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning];


Pssm-ID: 227399 [Multi-domain]  Cd Length: 468  Bit Score: 46.48  E-value: 4.90e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370472283 262 EPSPRSAAHTMPRR--KKGYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIAQL 319
Cdd:COG5067   405 ETGKDSAVHQKVKKetKKGYCENCREKYESLEQHIVSEKHRRFAENDLNFEALDSLFELL 464
 
Name Accession Description Interval E-value
zf-DBF pfam07535
DBF zinc finger; This domain is predicted to bind metal ions and is often found associated ...
 278-319 2.64e-16

DBF zinc finger; This domain is predicted to bind metal ions and is often found associated with pfam00533 and pfam02178. It was first identified in the Drosophila chiffon gene product, and is associated with initiation of DNA replication.


Pssm-ID: 462197  Cd Length: 42  Bit Score: 72.92  E-value: 2.64e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1370472283 278 GYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIAQL 319
Cdd:pfam07535   1 GYCENCRVKYEDLEEHIVSEKHRKFAENDSNFKELDELISKL 42
ZnF_DBF smart00586
Zinc finger in DBF-like proteins;
275-319 1.08e-11

Zinc finger in DBF-like proteins;


Pssm-ID: 128854 [Multi-domain]  Cd Length: 49  Bit Score: 59.80  E-value: 1.08e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1370472283  275 RKKGYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIAQL 319
Cdd:smart00586   3 KKPGYCENCREKYDDLETHLLSEKHRRFAENNDNFQALDDLISQL 47
DBF4 COG5067
Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, ...
 262-319 4.90e-05

Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning];


Pssm-ID: 227399 [Multi-domain]  Cd Length: 468  Bit Score: 46.48  E-value: 4.90e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370472283 262 EPSPRSAAHTMPRR--KKGYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIAQL 319
Cdd:COG5067   405 ETGKDSAVHQKVKKetKKGYCENCREKYESLEQHIVSEKHRRFAENDLNFEALDSLFELL 464
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH