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Conserved domains on  [gi|1370482776|ref|XP_024308080|]
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zinc finger BED domain-containing protein 4 isoform X1 [Homo sapiens]

Protein Classification

zf-BED and Dimer_Tnp_hAT domain-containing protein( domain architecture ID 10502528)

zf-BED and Dimer_Tnp_hAT domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-BED pfam02892
BED zinc finger;
118-166 2.39e-15

BED zinc finger;


:

Pssm-ID: 427043  Cd Length: 44  Bit Score: 70.86  E-value: 2.39e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  118 SPAWKHFFISPRDSTKAICMYCVKEFSRGKNekdlsTSCLMRHVRRAHP 166
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGGG-----TSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
459-506 4.78e-15

BED zinc finger;


:

Pssm-ID: 427043  Cd Length: 44  Bit Score: 70.09  E-value: 4.78e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1370482776  459 SEVWHHFSLAPMDSLKAECRYCGCAISRGKkgdvGTSCLMRHLYRRHP 506
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG----GTSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
288-336 2.26e-14

BED zinc finger;


:

Pssm-ID: 427043  Cd Length: 44  Bit Score: 68.16  E-value: 2.26e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  288 SAVWKHFYLSPLDNSKAVCIHCMNEFSRGKngkdlGTSCLIRHMWRAHR 336
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
561-609 4.74e-14

BED zinc finger;


:

Pssm-ID: 427043  Cd Length: 44  Bit Score: 67.01  E-value: 4.74e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  561 SKLWNHFSICSADSTKVVCLHCGRTISRGKkptnlGTSCLLRHLQRFHS 609
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
Dimer_Tnp_hAT super family cl05324
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1088-1164 9.70e-07

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


The actual alignment was detected with superfamily member pfam05699:

Pssm-ID: 399013  Cd Length: 83  Bit Score: 47.64  E-value: 9.70e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370482776 1088 YLEEEVLEHSC--DPLTYWNLKKASWPGLSALAVRFLGCPPSIVPSEKLFNTPTENGSLGQSRLMMEHFEKLIFLKVNL 1164
Cdd:pfam05699    5 YLSEPVLPRNEdfDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIEDWL 83
 
Name Accession Description Interval E-value
zf-BED pfam02892
BED zinc finger;
118-166 2.39e-15

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 70.86  E-value: 2.39e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  118 SPAWKHFFISPRDSTKAICMYCVKEFSRGKNekdlsTSCLMRHVRRAHP 166
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGGG-----TSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
459-506 4.78e-15

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 70.09  E-value: 4.78e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1370482776  459 SEVWHHFSLAPMDSLKAECRYCGCAISRGKkgdvGTSCLMRHLYRRHP 506
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG----GTSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
288-336 2.26e-14

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 68.16  E-value: 2.26e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  288 SAVWKHFYLSPLDNSKAVCIHCMNEFSRGKngkdlGTSCLIRHMWRAHR 336
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
561-609 4.74e-14

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 67.01  E-value: 4.74e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  561 SKLWNHFSICSADSTKVVCLHCGRTISRGKkptnlGTSCLLRHLQRFHS 609
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 460-508 1.49e-12

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 63.22  E-value: 1.49e-12
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 1370482776   460 EVWHHFSL-APMDSLK--AECRYCGCAISRGKKGdvGTSCLMRHLYRRHPEV 508
Cdd:smart00614    1 KVWKHFTLiLEKDNGKqrAKCKYCGKKLSRSSKG--GTSNLRRHLRRKHPAR 50
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 290-338 3.76e-11

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 58.98  E-value: 3.76e-11
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 1370482776   290 VWKHFYL-SPLDNSK--AVCIHCMNEFSRGKNGkdlGTSCLIRHMWRAHRAI 338
Cdd:smart00614    2 VWKHFTLiLEKDNGKqrAKCKYCGKKLSRSSKG---GTSNLRRHLRRKHPAR 50
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 120-168 7.94e-10

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 55.51  E-value: 7.94e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 1370482776   120 AWKHF-FISPRDSTK--AICMYCVKEFSRGKNekdLSTSCLMRHVRRAHPTV 168
Cdd:smart00614    2 VWKHFtLILEKDNGKqrAKCKYCGKKLSRSSK---GGTSNLRRHLRRKHPAR 50
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 562-611 1.30e-09

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 54.74  E-value: 1.30e-09
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 1370482776   562 KLWNHFS-ICSADSTK--VVCLHCGRTISRGKkptNLGTSCLLRHLQRFHSNV 611
Cdd:smart00614    1 KVWKHFTlILEKDNGKqrAKCKYCGKKLSRSS---KGGTSNLRRHLRRKHPAR 50
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1088-1164 9.70e-07

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 47.64  E-value: 9.70e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370482776 1088 YLEEEVLEHSC--DPLTYWNLKKASWPGLSALAVRFLGCPPSIVPSEKLFNTPTENGSLGQSRLMMEHFEKLIFLKVNL 1164
Cdd:pfam05699    5 YLSEPVLPRNEdfDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIEDWL 83
 
Name Accession Description Interval E-value
zf-BED pfam02892
BED zinc finger;
118-166 2.39e-15

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 70.86  E-value: 2.39e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  118 SPAWKHFFISPRDSTKAICMYCVKEFSRGKNekdlsTSCLMRHVRRAHP 166
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGGG-----TSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
459-506 4.78e-15

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 70.09  E-value: 4.78e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1370482776  459 SEVWHHFSLAPMDSLKAECRYCGCAISRGKkgdvGTSCLMRHLYRRHP 506
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG----GTSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
288-336 2.26e-14

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 68.16  E-value: 2.26e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  288 SAVWKHFYLSPLDNSKAVCIHCMNEFSRGKngkdlGTSCLIRHMWRAHR 336
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
zf-BED pfam02892
BED zinc finger;
561-609 4.74e-14

BED zinc finger;


Pssm-ID: 427043  Cd Length: 44  Bit Score: 67.01  E-value: 4.74e-14
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1370482776  561 SKLWNHFSICSADSTKVVCLHCGRTISRGKkptnlGTSCLLRHLQRFHS 609
Cdd:pfam02892    1 SKVWKYFRELPLDETKAVCRYCGKILSRGG-----GTSNLIRHLRRKHP 44
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 460-508 1.49e-12

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 63.22  E-value: 1.49e-12
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 1370482776   460 EVWHHFSL-APMDSLK--AECRYCGCAISRGKKGdvGTSCLMRHLYRRHPEV 508
Cdd:smart00614    1 KVWKHFTLiLEKDNGKqrAKCKYCGKKLSRSSKG--GTSNLRRHLRRKHPAR 50
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 290-338 3.76e-11

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 58.98  E-value: 3.76e-11
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 1370482776   290 VWKHFYL-SPLDNSK--AVCIHCMNEFSRGKNGkdlGTSCLIRHMWRAHRAI 338
Cdd:smart00614    2 VWKHFTLiLEKDNGKqrAKCKYCGKKLSRSSKG---GTSNLRRHLRRKHPAR 50
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 120-168 7.94e-10

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 55.51  E-value: 7.94e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 1370482776   120 AWKHF-FISPRDSTK--AICMYCVKEFSRGKNekdLSTSCLMRHVRRAHPTV 168
Cdd:smart00614    2 VWKHFtLILEKDNGKqrAKCKYCGKKLSRSSK---GGTSNLRRHLRRKHPAR 50
ZnF_BED smart00614
BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and ...
 562-611 1.30e-09

BED zinc finger; DNA-binding domain in chromatin-boundary-element-binding proteins and transposases


Pssm-ID: 214746 [Multi-domain]  Cd Length: 50  Bit Score: 54.74  E-value: 1.30e-09
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 1370482776   562 KLWNHFS-ICSADSTK--VVCLHCGRTISRGKkptNLGTSCLLRHLQRFHSNV 611
Cdd:smart00614    1 KVWKHFTlILEKDNGKqrAKCKYCGKKLSRSS---KGGTSNLRRHLRRKHPAR 50
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 1088-1164 9.70e-07

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 47.64  E-value: 9.70e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370482776 1088 YLEEEVLEHSC--DPLTYWNLKKASWPGLSALAVRFLGCPPSIVPSEKLFNTPTENGSLGQSRLMMEHFEKLIFLKVNL 1164
Cdd:pfam05699    5 YLSEPVLPRNEdfDPLEWWKENSSRYPNLSKLARDILSIPVSSAASERSFSTLGKVILESRNRLEPLNVEALLCIEDWL 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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