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Conserved domains on  [gi|1720399168|ref|XP_030107026|]
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double zinc ribbon and ankyrin repeat-containing protein 1 isoform X7 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
564-678 9.57e-17

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 81.15  E-value: 9.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDQQwGPFRNTALHEATLLGLEgrESIATLL 643
Cdd:COG0666   130 NGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNAR-DNDGETPLHLAAENGHL--EIVKLLL 206

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1720399168 644 GCNANAQKKNTRGQTAYDIALEMGDDLTSSLFAAK 678
Cdd:COG0666   207 EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241
Fn3_assoc pfam13287
Fn3 associated;
32-100 8.39e-13

Fn3 associated;


:

Pssm-ID: 463829 [Multi-domain]  Cd Length: 59  Bit Score: 63.46  E-value: 8.39e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720399168  32 LEMKSDTPDVNIYYTLDGSKPDflkkvgsgeNNTFKYVKPITLPDGKiQVKAVAVSKDCRQSGIVTKVF 100
Cdd:pfam13287   1 VTLTSETPGAEIYYTTDGSDPT---------TNSPKYTQPIVINENT-TIKAIAVRPGKNISKVVTETY 59
DZR pfam12773
Double zinc ribbon; This family consists of a pair of zinc ribbon domains.
 273-327 1.06e-10

Double zinc ribbon; This family consists of a pair of zinc ribbon domains.


:

Pssm-ID: 432773 [Multi-domain]  Cd Length: 45  Bit Score: 57.00  E-value: 1.06e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720399168 273 CRTCGTGNPAHLRYCVTCEGPLPPTqelgisashsVCPKCGASNHLTARFCGSCG 327
Cdd:pfam12773   1 CPNCGHPNPPGAKFCPACGTPLKPD----------RCPNCGAPVPPNARFCPYCG 45
Nudix_N_2 super family cl48264
Nudix N-terminal; Ths domain occurs at the N-terminus of several Nudix (Nucleoside Diphosphate ...
 244-278 2.58e-04

Nudix N-terminal; Ths domain occurs at the N-terminus of several Nudix (Nucleoside Diphosphate linked to X) hydrolases.


The actual alignment was detected with superfamily member pfam14803:

Pssm-ID: 464323  Cd Length: 32  Bit Score: 38.62  E-value: 2.58e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1720399168 244 RFCHECGAPVppifGYRLPPPEGaQERVICRTCGT 278
Cdd:pfam14803   1 KFCSQCGGPV----ELRIPDGDN-RPRLVCTACGT 30
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
564-678 9.57e-17

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 81.15  E-value: 9.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDQQwGPFRNTALHEATLLGLEgrESIATLL 643
Cdd:COG0666   130 NGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNAR-DNDGETPLHLAAENGHL--EIVKLLL 206

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1720399168 644 GCNANAQKKNTRGQTAYDIALEMGDDLTSSLFAAK 678
Cdd:COG0666   207 EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241
Fn3_assoc pfam13287
Fn3 associated;
32-100 8.39e-13

Fn3 associated;


Pssm-ID: 463829 [Multi-domain]  Cd Length: 59  Bit Score: 63.46  E-value: 8.39e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720399168  32 LEMKSDTPDVNIYYTLDGSKPDflkkvgsgeNNTFKYVKPITLPDGKiQVKAVAVSKDCRQSGIVTKVF 100
Cdd:pfam13287   1 VTLTSETPGAEIYYTTDGSDPT---------TNSPKYTQPIVINENT-TIKAIAVRPGKNISKVVTETY 59
DZR pfam12773
Double zinc ribbon; This family consists of a pair of zinc ribbon domains.
 273-327 1.06e-10

Double zinc ribbon; This family consists of a pair of zinc ribbon domains.


Pssm-ID: 432773 [Multi-domain]  Cd Length: 45  Bit Score: 57.00  E-value: 1.06e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720399168 273 CRTCGTGNPAHLRYCVTCEGPLPPTqelgisashsVCPKCGASNHLTARFCGSCG 327
Cdd:pfam12773   1 CPNCGHPNPPGAKFCPACGTPLKPD----------RCPNCGAPVPPNARFCPYCG 45
Ank_2 pfam12796
Ankyrin repeats (3 copies);
564-653 6.07e-08

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 50.88  E-value: 6.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRgADIDQQwgPFRNTALHEATLLGLEgrESIATLL 643
Cdd:pfam12796   7 NGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLK--DNGRTALHYAARSGHL--EIVKLLL 81

                          90
                  ....*....|
gi 1720399168 644 GCNANAQKKN 653
Cdd:pfam12796  82 EKGADINVKD 91
Nudix_N_2 pfam14803
Nudix N-terminal; Ths domain occurs at the N-terminus of several Nudix (Nucleoside Diphosphate ...
 244-278 2.58e-04

Nudix N-terminal; Ths domain occurs at the N-terminus of several Nudix (Nucleoside Diphosphate linked to X) hydrolases.


Pssm-ID: 464323  Cd Length: 32  Bit Score: 38.62  E-value: 2.58e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1720399168 244 RFCHECGAPVppifGYRLPPPEGaQERVICRTCGT 278
Cdd:pfam14803   1 KFCSQCGGPV----ELRIPDGDN-RPRLVCTACGT 30
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 531-628 2.80e-04

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 44.09  E-value: 2.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 531 KKMKNLKAKSFLV-----NPEPLTPENKLLLEEVGSSGkgrlsVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPV 605
Cdd:PLN03192  502 KELHDLNVGDLLGdnggeHDDPNMASNLLTVASTGNAA-----LLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLV 576

                          90       100
                  ....*....|....*....|....*.
gi 1720399168 606 LAQRGADI---DQQwgpfRNTALHEA 628
Cdd:PLN03192  577 LLKHACNVhirDAN----GNTALWNA 598
PRK14559 PRK14559
serine/threonine phosphatase;
271-378 8.28e-04

serine/threonine phosphatase;


Pssm-ID: 237756 [Multi-domain]  Cd Length: 645  Bit Score: 42.74  E-value: 8.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 271 VICRTCGTGNPAHLRYCVTCegplpptqelGISASHSVCPKCGASNHLTARFCGSCGIYVKsiTRFRMHNSLAIVAGAPR 350
Cdd:PRK14559    2 LICPQCQFENPNNNRFCQKC----------GTSLTHKPCPQCGTEVPVDEAHCPNCGAETG--TIWWAIIAQASPNSEVL 69

                          90       100
                  ....*....|....*....|....*...
gi 1720399168 351 PFPEPRSAWQSLNVPLPTSASGSKKDTG 378
Cdd:PRK14559   70 ESGEATQQSESSLTPSSSPLYGSYLDPG 97
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
564-678 9.57e-17

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 81.15  E-value: 9.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDQQwGPFRNTALHEATLLGLEgrESIATLL 643
Cdd:COG0666   130 NGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNAR-DNDGETPLHLAAENGHL--EIVKLLL 206

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1720399168 644 GCNANAQKKNTRGQTAYDIALEMGDDLTSSLFAAK 678
Cdd:COG0666   207 EAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
564-668 1.29e-15

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 78.07  E-value: 1.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDQQwGPFRNTALHEATllgLEGRESIATLL 643
Cdd:COG0666    97 NGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQ-DNDGNTPLHLAA---ANGNLEIVKLL 172

                          90       100
                  ....*....|....*....|....*...
gi 1720399168 644 ---GCNANAQkkNTRGQTAYDIALEMGD 668
Cdd:COG0666   173 leaGADVNAR--DNDGETPLHLAAENGH 198
Fn3_assoc pfam13287
Fn3 associated;
32-100 8.39e-13

Fn3 associated;


Pssm-ID: 463829 [Multi-domain]  Cd Length: 59  Bit Score: 63.46  E-value: 8.39e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720399168  32 LEMKSDTPDVNIYYTLDGSKPDflkkvgsgeNNTFKYVKPITLPDGKiQVKAVAVSKDCRQSGIVTKVF 100
Cdd:pfam13287   1 VTLTSETPGAEIYYTTDGSDPT---------TNSPKYTQPIVINENT-TIKAIAVRPGKNISKVVTETY 59
DZR pfam12773
Double zinc ribbon; This family consists of a pair of zinc ribbon domains.
 273-327 1.06e-10

Double zinc ribbon; This family consists of a pair of zinc ribbon domains.


Pssm-ID: 432773 [Multi-domain]  Cd Length: 45  Bit Score: 57.00  E-value: 1.06e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1720399168 273 CRTCGTGNPAHLRYCVTCEGPLPPTqelgisashsVCPKCGASNHLTARFCGSCG 327
Cdd:pfam12773   1 CPNCGHPNPPGAKFCPACGTPLKPD----------RCPNCGAPVPPNARFCPYCG 45
CHB_HEX_C_1 pfam13290
Chitobiase/beta-hexosaminidase C-terminal domain;
27-97 4.64e-08

Chitobiase/beta-hexosaminidase C-terminal domain;


Pssm-ID: 433091 [Multi-domain]  Cd Length: 67  Bit Score: 50.36  E-value: 4.64e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720399168  27 DTNTLLEMKSDTPDVNIYYTLDGSKPDFlkkvgsgenNTFKYVKPITLPDGKiQVKAVAVSKDCRQSGIVT 97
Cdd:pfam13290   7 SSAQTVTLSTATEGATIYYTTDGSEPTT---------SSPKYTGPITISSTT-TIKAIAVDDGGNSSAVVT 67
Ank_2 pfam12796
Ankyrin repeats (3 copies);
564-653 6.07e-08

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 50.88  E-value: 6.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRgADIDQQwgPFRNTALHEATLLGLEgrESIATLL 643
Cdd:pfam12796   7 NGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLK--DNGRTALHYAARSGHL--EIVKLLL 81

                          90
                  ....*....|
gi 1720399168 644 GCNANAQKKN 653
Cdd:pfam12796  82 EKGADINVKD 91
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
564-668 1.12e-07

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 53.80  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDQQwGPFRNTALHEATLLGLEgrESIATLL 643
Cdd:COG0666    64 AGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNAR-DKDGETPLHLAAYNGNL--EIVKLLL 140

                          90       100
                  ....*....|....*....|....*
gi 1720399168 644 GCNANAQKKNTRGQTAYDIALEMGD 668
Cdd:COG0666   141 EAGADVNAQDNDGNTPLHLAAANGN 165
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
564-653 9.59e-05

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 44.94  E-value: 9.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVLAQRGADIDqQWGPFRNTALHEATLLGLEGRESIATLL 643
Cdd:COG0666   196 NGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLN-AKDKDGLTALLLAAAAGAALIVKLLLLA 274

                          90
                  ....*....|
gi 1720399168 644 GCNANAQKKN 653
Cdd:COG0666   275 LLLLAAALLD 284
Nudix_N_2 pfam14803
Nudix N-terminal; Ths domain occurs at the N-terminus of several Nudix (Nucleoside Diphosphate ...
 244-278 2.58e-04

Nudix N-terminal; Ths domain occurs at the N-terminus of several Nudix (Nucleoside Diphosphate linked to X) hydrolases.


Pssm-ID: 464323  Cd Length: 32  Bit Score: 38.62  E-value: 2.58e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1720399168 244 RFCHECGAPVppifGYRLPPPEGaQERVICRTCGT 278
Cdd:pfam14803   1 KFCSQCGGPV----ELRIPDGDN-RPRLVCTACGT 30
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 531-628 2.80e-04

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 44.09  E-value: 2.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 531 KKMKNLKAKSFLV-----NPEPLTPENKLLLEEVGSSGkgrlsVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPV 605
Cdd:PLN03192  502 KELHDLNVGDLLGdnggeHDDPNMASNLLTVASTGNAA-----LLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLV 576

                          90       100
                  ....*....|....*....|....*.
gi 1720399168 606 LAQRGADI---DQQwgpfRNTALHEA 628
Cdd:PLN03192  577 LLKHACNVhirDAN----GNTALWNA 598
Ank_2 pfam12796
Ankyrin repeats (3 copies);
592-667 2.86e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 40.48  E-value: 2.86e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720399168 592 IVAVVNKHYEAIPVLAQRGADIDQQwGPFRNTALHEATllgLEGRESIATLLgCNANAQKKNTRGQTAYDIALEMG 667
Cdd:pfam12796   2 HLAAKNGNLELVKLLLENGADANLQ-DKNGRTALHLAA---KNGHLEIVKLL-LEHADVNLKDNGRTALHYAARSG 72
Ank_4 pfam13637
Ankyrin repeats (many copies);
564-606 3.78e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 38.79  E-value: 3.78e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1720399168 564 KGRLSVLEQLLDEGADPNCCDSQGRPAVIVAVVNKHYEAIPVL 606
Cdd:pfam13637  11 SGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
DZR pfam12773
Double zinc ribbon; This family consists of a pair of zinc ribbon domains.
 309-334 7.81e-04

Double zinc ribbon; This family consists of a pair of zinc ribbon domains.


Pssm-ID: 432773 [Multi-domain]  Cd Length: 45  Bit Score: 37.74  E-value: 7.81e-04
                          10        20
                  ....*....|....*....|....*.
gi 1720399168 309 CPKCGASNHLTARFCGSCGIYVKSIT 334
Cdd:pfam12773   1 CPNCGHPNPPGAKFCPACGTPLKPDR 26
PRK14559 PRK14559
serine/threonine phosphatase;
271-378 8.28e-04

serine/threonine phosphatase;


Pssm-ID: 237756 [Multi-domain]  Cd Length: 645  Bit Score: 42.74  E-value: 8.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720399168 271 VICRTCGTGNPAHLRYCVTCegplpptqelGISASHSVCPKCGASNHLTARFCGSCGIYVKsiTRFRMHNSLAIVAGAPR 350
Cdd:PRK14559    2 LICPQCQFENPNNNRFCQKC----------GTSLTHKPCPQCGTEVPVDEAHCPNCGAETG--TIWWAIIAQASPNSEVL 69

                          90       100
                  ....*....|....*....|....*...
gi 1720399168 351 PFPEPRSAWQSLNVPLPTSASGSKKDTG 378
Cdd:PRK14559   70 ESGEATQQSESSLTPSSSPLYGSYLDPG 97
zinc_ribbon_2 pfam13240
zinc-ribbon domain; This family consists of a single zinc ribbon domain, ie half of a pair as ...
 309-327 3.90e-03

zinc-ribbon domain; This family consists of a single zinc ribbon domain, ie half of a pair as in family DZR. pfam12773.


Pssm-ID: 433054 [Multi-domain]  Cd Length: 21  Bit Score: 35.17  E-value: 3.90e-03
                          10
                  ....*....|....*....
gi 1720399168 309 CPKCGASNHLTARFCGSCG 327
Cdd:pfam13240   2 CPNCGAENPDGAKFCPKCG 20
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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