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Conserved domains on  [gi|1799935025|ref|XP_031948719|]
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alanine aminotransferase 1-like isoform X5 [Corvus moneduloides]

Protein Classification

alanine aminotransferase( domain architecture ID 1002570)

alanine aminotransferase catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate

CATH:  3.40.640.10|1.10.287.1970|3.90.1150.10
EC:  2.6.1.2
Gene Ontology:  GO:0009058|GO:0030170|GO:0004021

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00377 super family cl30205
alanine aminotransferase; Provisional
 79-432 1.04e-73

alanine aminotransferase; Provisional


The actual alignment was detected with superfamily member PTZ00377:

Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 238.71  E-value: 1.04e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025  79 QAP-AFLRQVAAICAYPALLEHEDI----PESAKEHARRILRElMGGSPGAYNLEYVTGAVAERAARFLAHRDrGIACDP 153
Cdd:PTZ00377   61 QKPlTFYRQVLSLVEYPFLLEDPSVsslfPADVVARAKEYLNA-IGGGTGAYTDSAGYPFVRKAVAAFIERRD-GVPKDP 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 154 ANIVPCAGTAAAVVDVLSLVVCPGSalpTGVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREARSR 233
Cdd:PTZ00377  139 SDIFLTDGASSGIKLLLQLLIGDPS---DGVMIPIPQYPLYSAAITLLGGKQVPYYLDEEKGWSLDQEELEEAYEQAVRN 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 234 -CHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERPFLSFKRVLAELGAPLATSVQLVSFY 312
Cdd:PTZ00377  216 gITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDGEKPFISFRKVLLELPAEYNTDVELVSFH 295

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 313 SLSKGIGGG-GFRAGFLELVNIERSVLRGFY---TWGLSvyPPILGQVMLDVAMEPPGHRDPASAAMEEHRRDLCRDLAA 388
Cdd:PTZ00377  296 STSKGIIGEcGRRGGYFELTNIPPEVREQIYklaSINLC--SNVVGQLMTGLMCNPPREGDASYPLYKRERDAIFTSLKR 373

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1799935025 389 NARRLQEELGRAPGIRCQPLAGGPRAFPRIRIPPRARSQARATG 432
Cdd:PTZ00377  374 RAELLTDELNKIEGVSCQPVEGAMYAFPRIELPEKAIQEAKERG 417
 
Name Accession Description Interval E-value
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
 79-432 1.04e-73

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 238.71  E-value: 1.04e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025  79 QAP-AFLRQVAAICAYPALLEHEDI----PESAKEHARRILRElMGGSPGAYNLEYVTGAVAERAARFLAHRDrGIACDP 153
Cdd:PTZ00377   61 QKPlTFYRQVLSLVEYPFLLEDPSVsslfPADVVARAKEYLNA-IGGGTGAYTDSAGYPFVRKAVAAFIERRD-GVPKDP 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 154 ANIVPCAGTAAAVVDVLSLVVCPGSalpTGVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREARSR 233
Cdd:PTZ00377  139 SDIFLTDGASSGIKLLLQLLIGDPS---DGVMIPIPQYPLYSAAITLLGGKQVPYYLDEEKGWSLDQEELEEAYEQAVRN 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 234 -CHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERPFLSFKRVLAELGAPLATSVQLVSFY 312
Cdd:PTZ00377  216 gITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDGEKPFISFRKVLLELPAEYNTDVELVSFH 295

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 313 SLSKGIGGG-GFRAGFLELVNIERSVLRGFY---TWGLSvyPPILGQVMLDVAMEPPGHRDPASAAMEEHRRDLCRDLAA 388
Cdd:PTZ00377  296 STSKGIIGEcGRRGGYFELTNIPPEVREQIYklaSINLC--SNVVGQLMTGLMCNPPREGDASYPLYKRERDAIFTSLKR 373

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1799935025 389 NARRLQEELGRAPGIRCQPLAGGPRAFPRIRIPPRARSQARATG 432
Cdd:PTZ00377  374 RAELLTDELNKIEGVSCQPVEGAMYAFPRIELPEKAIQEAKERG 417
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 136-430 2.98e-20

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 91.25  E-value: 2.98e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 136 ERAARFLAhRDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSAlptgVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRG 215
Cdd:cd00609    43 EAIAEWLG-RRGGVDVPPEEIVVTNGAQEALSLLLRALLNPGDE----VLVPDPTYPGYEAAARLAGAEVVPVPLDEEGG 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 216 WAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERPFLSfkrvl 295
Cdd:cd00609   118 FLLDLELLEAAKTP-----KTKLLYLNNPNNPTGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPAL----- 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 296 aelgAPLATSVQLVSFYSLSKGIGGGGFRAGFLELVNIE-RSVLRGFYTWGLSVyPPILGQVMLDVAMEPPghrdpasaa 374
Cdd:cd00609   188 ----ALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEElLERLKKLLPYTTSG-PSTLSQAAAAAALDDG--------- 253

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1799935025 375 mEEHRRDLCRDLAANARRLQEELGRAPGIRCQPLAGGPRAFPRIRIPPRARSQARA 430
Cdd:cd00609   254 -EEHLEELRERYRRRRDALLEALKELGPLVVVKPSGGFFLWLDLPEGDDEEFLERL 308
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 136-419 1.76e-14

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 74.40  E-value: 1.76e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 136 ERAARFLAhRDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSAlptgVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRG 215
Cdd:COG0436    74 EAIAAYYK-RRYGVDLDPDEILVTNGAKEALALALLALLNPGDE----VLVPDPGYPSYRAAVRLAGGKPVPVPLDEENG 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 216 WAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERP--FLSFKR 293
Cdd:COG0436   149 FLPDPEALEAAITP-----RTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHvsILSLPG 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 294 vLAElgaplatsvQLVSFYSLSKGIGGGGFRAGFL----ELVN-IERsvLRGFYTWGlsvyPPILGQVMLDVAMEPPghr 368
Cdd:COG0436   224 -LKD---------RTIVINSFSKSYAMTGWRIGYAvgppELIAaLLK--LQSNLTSC----APTPAQYAAAAALEGP--- 284

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1799935025 369 dpasaamEEHRRDLCRDLAANARRLQEELGRApGIRCQPLAGGPRAFPRIR 419
Cdd:COG0436   285 -------QDYVEEMRAEYRRRRDLLVEGLNEI-GLSVVKPEGAFYLFADVP 327
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
101-411 2.15e-14

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 73.88  E-value: 2.15e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 101 DIPESAKEHARRIL--RELMGGSPGAYNLEYVtgavaERAARFLaHRDRGIACDP-ANIVPCAGTAAAVVDVLSLVVCPG 177
Cdd:pfam00155  14 DTLPAVAKAEKDALagGTRNLYGPTDGHPELR-----EALAKFL-GRSPVLKLDReAAVVFGSGAGANIEALIFLLANPG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 178 SAlptgVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREArsrchPRVLWVVNPGDPTGHVLSRPDM 257
Cdd:pfam00155  88 DA----ILVPAPTYASYIRIARLAGGEVVRYPLYDSNDFHLDFDALEAALKEK-----PKVVLHTSPHNPTGTVATLEEL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 258 ESIVRLAAEEPLLLLADEVHQERAFSPErpflSFKRVLAElgapLATSVQLVSFYSLSKGIGGGGFRAGFL----ELVNI 333
Cdd:pfam00155 159 EKLLDLAKEHNILLLVDEAYAGFVFGSP----DAVATRAL----LAEGPNLLVVGSFSKAFGLAGWRVGYIlgnaAVISQ 230

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1799935025 334 ERSVLRGFYTwglsvypPILGQVMLDVAMEPPGHRDPASAAMEEHrrdlcrdLAANARRLQEELgRAPGIRCQPLAGG 411
Cdd:pfam00155 231 LRKLARPFYS-------STHLQAAAAAALSDPLLVASELEEMRQR-------IKERRDYLRDGL-QAAGLSVLPSQAG 293
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
 136-341 1.54e-06

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 50.17  E-value: 1.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 136 ERAARFLAHRDRGIACDpaNIVPCAGTAAAVVDVLSLVVCPGSalptGVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRG 215
Cdd:TIGR01264  80 EAIASYYHNPDGPIEAD--DVVLCSGCSHAIEMCIAALANAGQ----NILVPRPGFPLYETLAESMGIEVKLYNLLPDKS 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 216 WAVDVAALRREVREaRSRChprvLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFsPERPFLSFkrvl 295
Cdd:TIGR01264 154 WEIDLKQLESLIDE-KTAA----LIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVF-SGATFEPL---- 223

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1799935025 296 aelgAPLATSVQLVSFYSLSKGIGGGGFRAGFLELVNiERSVLRGF 341
Cdd:TIGR01264 224 ----ASLSSTVPILSCGGLAKRWLVPGWRLGWIIIHD-RRGILRDI 264
 
Name Accession Description Interval E-value
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
 79-432 1.04e-73

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 238.71  E-value: 1.04e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025  79 QAP-AFLRQVAAICAYPALLEHEDI----PESAKEHARRILRElMGGSPGAYNLEYVTGAVAERAARFLAHRDrGIACDP 153
Cdd:PTZ00377   61 QKPlTFYRQVLSLVEYPFLLEDPSVsslfPADVVARAKEYLNA-IGGGTGAYTDSAGYPFVRKAVAAFIERRD-GVPKDP 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 154 ANIVPCAGTAAAVVDVLSLVVCPGSalpTGVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREARSR 233
Cdd:PTZ00377  139 SDIFLTDGASSGIKLLLQLLIGDPS---DGVMIPIPQYPLYSAAITLLGGKQVPYYLDEEKGWSLDQEELEEAYEQAVRN 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 234 -CHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERPFLSFKRVLAELGAPLATSVQLVSFY 312
Cdd:PTZ00377  216 gITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDGEKPFISFRKVLLELPAEYNTDVELVSFH 295

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 313 SLSKGIGGG-GFRAGFLELVNIERSVLRGFY---TWGLSvyPPILGQVMLDVAMEPPGHRDPASAAMEEHRRDLCRDLAA 388
Cdd:PTZ00377  296 STSKGIIGEcGRRGGYFELTNIPPEVREQIYklaSINLC--SNVVGQLMTGLMCNPPREGDASYPLYKRERDAIFTSLKR 373

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 1799935025 389 NARRLQEELGRAPGIRCQPLAGGPRAFPRIRIPPRARSQARATG 432
Cdd:PTZ00377  374 RAELLTDELNKIEGVSCQPVEGAMYAFPRIELPEKAIQEAKERG 417
PLN02368 PLN02368
alanine transaminase
 75-429 3.50e-54

alanine transaminase


Pssm-ID: 177996 [Multi-domain]  Cd Length: 407  Bit Score: 185.39  E-value: 3.50e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025  75 AEGRQAPAFLRQVAAICAYPALLEHEDI----PESAKEHARRILRELMGGSpGAYNLEYVTGAVAERAARFLAHRDrGIA 150
Cdd:PLN02368   50 ALGQKPLTFPRQVVALCQAPFLLDDPNVgllfPADAIARAKHYLSLTSGGL-GAYSDSRGLPGVRKEVAEFIERRD-GYP 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 151 CDPANIVPCAGTAAAVVDVLSLVVcpgSALPTGVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREA 230
Cdd:PLN02368  128 SDPELIFLTDGASKGVMQILNAVI---RGEKDGVLVPVPQYPLYSATISLLGGTLVPYYLEESENWGLDVNNLRQSVAQA 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 231 RSR-CHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERPFLSFKRVLAELGAPLATSVQLV 309
Cdd:PLN02368  205 RSKgITVRAMVIINPGNPTGQCLSEANLREILKFCYQERLVLLGDEVYQQNIYQDERPFISAKKVLMDMGPPISKEVQLV 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 310 SFYSLSKGIGGG-GFRAGFLELVNIERSVLRGFY-TWGLSVYPPILGQVMLDVAMEPPGHRDPASAAMEEHRRDLCRDLA 387
Cdd:PLN02368  285 SFHTVSKGYWGEcGQRGGYFEMTNIPPKTVEEIYkVASIALSPNVSGQIFMGLMVNPPKPGDISYDQFVRESKGILESLR 364

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 1799935025 388 ANARRLQEELGRAPGIRCQPLAGGPRAFPRIRIPPRARSQAR 429
Cdd:PLN02368  365 RRARMMTDGFNSCKNVVCNFTEGAMYSFPQIKLPPKAIEAAR 406
PLN02231 PLN02231
alanine transaminase
 77-432 1.85e-45

alanine transaminase


Pssm-ID: 177876 [Multi-domain]  Cd Length: 534  Bit Score: 165.11  E-value: 1.85e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025  77 GRQAPAFLRQVAAICAYPALLEHED----IPESAKEHARRILRELMGGSPGAYNLEYVTGAVAERAARFLAHRDrGIACD 152
Cdd:PLN02231  112 GQQPITFFREVLALCDHPSLLDKSEthglFSADAIERAWQILDQIPGRATGAYSHSQGIKGLRDAIAAGIEARD-GFPAD 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 153 PANIVPCAGTAAAVVDVLSLVVcpgSALPTGVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREARS 232
Cdd:PLN02231  191 PNDIFLTDGASPAVHMMMQLLI---RSEKDGILCPIPQYPLYSASIALHGGTLVPYYLDEATGWGLEISELKKQLEDARS 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 233 R-CHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERPFLSFKRVLAELGAPlATSVQLVSF 311
Cdd:PLN02231  268 KgITVRALVVINPGNPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENVYVPDKKFHSFKKVARSMGYG-EKDISLVSF 346

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 312 YSLSKGIGGG-GFRAGFLELVNIERSVLRGFYTWG-LSVYPPILGQVMLDVAMEPPGHRDPASAAMEEHRRDLCRDLAAN 389
Cdd:PLN02231  347 QSVSKGYYGEcGKRGGYMEVTGFTSDVREQIYKVAsVNLCSNISGQILASLVMSPPKPGDESYESYMAEKDGILSSLARR 426

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 1799935025 390 ARRLQEELGRAPGIRCQPLAGGPRAFPRIRIPPRARSQARATG 432
Cdd:PLN02231  427 AKTLEDALNSLEGVTCNKAEGAMYLFPRIHLPQKAIKAAEAAK 469
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 136-430 2.98e-20

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 91.25  E-value: 2.98e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 136 ERAARFLAhRDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSAlptgVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRG 215
Cdd:cd00609    43 EAIAEWLG-RRGGVDVPPEEIVVTNGAQEALSLLLRALLNPGDE----VLVPDPTYPGYEAAARLAGAEVVPVPLDEEGG 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 216 WAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERPFLSfkrvl 295
Cdd:cd00609   118 FLLDLELLEAAKTP-----KTKLLYLNNPNNPTGAVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPAL----- 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 296 aelgAPLATSVQLVSFYSLSKGIGGGGFRAGFLELVNIE-RSVLRGFYTWGLSVyPPILGQVMLDVAMEPPghrdpasaa 374
Cdd:cd00609   188 ----ALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEElLERLKKLLPYTTSG-PSTLSQAAAAAALDDG--------- 253

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1799935025 375 mEEHRRDLCRDLAANARRLQEELGRAPGIRCQPLAGGPRAFPRIRIPPRARSQARA 430
Cdd:cd00609   254 -EEHLEELRERYRRRRDALLEALKELGPLVVVKPSGGFFLWLDLPEGDDEEFLERL 308
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 136-419 1.76e-14

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 74.40  E-value: 1.76e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 136 ERAARFLAhRDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSAlptgVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRG 215
Cdd:COG0436    74 EAIAAYYK-RRYGVDLDPDEILVTNGAKEALALALLALLNPGDE----VLVPDPGYPSYRAAVRLAGGKPVPVPLDEENG 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 216 WAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERP--FLSFKR 293
Cdd:COG0436   149 FLPDPEALEAAITP-----RTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHvsILSLPG 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 294 vLAElgaplatsvQLVSFYSLSKGIGGGGFRAGFL----ELVN-IERsvLRGFYTWGlsvyPPILGQVMLDVAMEPPghr 368
Cdd:COG0436   224 -LKD---------RTIVINSFSKSYAMTGWRIGYAvgppELIAaLLK--LQSNLTSC----APTPAQYAAAAALEGP--- 284

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1799935025 369 dpasaamEEHRRDLCRDLAANARRLQEELGRApGIRCQPLAGGPRAFPRIR 419
Cdd:COG0436   285 -------QDYVEEMRAEYRRRRDLLVEGLNEI-GLSVVKPEGAFYLFADVP 327
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
101-411 2.15e-14

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 73.88  E-value: 2.15e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 101 DIPESAKEHARRIL--RELMGGSPGAYNLEYVtgavaERAARFLaHRDRGIACDP-ANIVPCAGTAAAVVDVLSLVVCPG 177
Cdd:pfam00155  14 DTLPAVAKAEKDALagGTRNLYGPTDGHPELR-----EALAKFL-GRSPVLKLDReAAVVFGSGAGANIEALIFLLANPG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 178 SAlptgVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREArsrchPRVLWVVNPGDPTGHVLSRPDM 257
Cdd:pfam00155  88 DA----ILVPAPTYASYIRIARLAGGEVVRYPLYDSNDFHLDFDALEAALKEK-----PKVVLHTSPHNPTGTVATLEEL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 258 ESIVRLAAEEPLLLLADEVHQERAFSPErpflSFKRVLAElgapLATSVQLVSFYSLSKGIGGGGFRAGFL----ELVNI 333
Cdd:pfam00155 159 EKLLDLAKEHNILLLVDEAYAGFVFGSP----DAVATRAL----LAEGPNLLVVGSFSKAFGLAGWRVGYIlgnaAVISQ 230

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1799935025 334 ERSVLRGFYTwglsvypPILGQVMLDVAMEPPGHRDPASAAMEEHrrdlcrdLAANARRLQEELgRAPGIRCQPLAGG 411
Cdd:pfam00155 231 LRKLARPFYS-------STHLQAAAAAALSDPLLVASELEEMRQR-------IKERRDYLRDGL-QAAGLSVLPSQAG 293
PRK08363 PRK08363
alanine aminotransferase; Validated
 103-422 2.73e-11

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 64.83  E-value: 2.73e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 103 PESAKEHARRILRE---LMGGSPGAYNLEYvtgAVAERAarflaHRDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSA 179
Cdd:PRK08363   48 PEHMKEAYCRAIKEghnYYGPSEGLPELRE---AIVKRE-----KRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 180 lptgVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMES 259
Cdd:PRK08363  120 ----ILIPGPSYPPYTGLVKFYGGVPVEYRTIEEEGWQPDIDDIRKKITE-----KTKAIAVINPNNPTGALYEKKTLKE 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 260 IVRLAAEEPLLLLADEVHQERAFspERPFLSFkrvlaelgAPLATSVQLVSFYSLSKGIGGGGFRAGFLELVNIE----- 334
Cdd:PRK08363  191 ILDIAGEHDLPVISDEIYDLMTY--EGKHVSP--------GSLTKDVPVIVMNGLSKVYFATGWRLGYIYFVDPEgklae 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 335 -RSVLRGFYTWGLSVYPPIlgQV-MLDVAMEPPGHRDPASAAMEEhRRDLCrdlaanARRLQEelgrAPGIRCQPLAGGP 412
Cdd:PRK08363  261 vREAIDKLARIRLCPNTPA--QFaAIAGLTGPMDYLEEYMKKLKE-RRDYI------YKRLNE----IPGISTTKPQGAF 327

                         330
                  ....*....|
gi 1799935025 413 RAFPRIRIPP 422
Cdd:PRK08363  328 YIFPRIEEGP 337
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
 136-341 1.54e-06

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 50.17  E-value: 1.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 136 ERAARFLAHRDRGIACDpaNIVPCAGTAAAVVDVLSLVVCPGSalptGVLVPVPGPPLCAAAAGLAGAVPVPYPLDESRG 215
Cdd:TIGR01264  80 EAIASYYHNPDGPIEAD--DVVLCSGCSHAIEMCIAALANAGQ----NILVPRPGFPLYETLAESMGIEVKLYNLLPDKS 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 216 WAVDVAALRREVREaRSRChprvLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFsPERPFLSFkrvl 295
Cdd:TIGR01264 154 WEIDLKQLESLIDE-KTAA----LIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVF-SGATFEPL---- 223

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1799935025 296 aelgAPLATSVQLVSFYSLSKGIGGGGFRAGFLELVNiERSVLRGF 341
Cdd:TIGR01264 224 ----ASLSSTVPILSCGGLAKRWLVPGWRLGWIIIHD-RRGILRDI 264
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
 133-346 2.35e-06

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 49.65  E-value: 2.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 133 AVAERAARFLAHRdrgiaCDPANIVPCAGTAAAVVDVLSLVVCPGSalptGVLVPVPGPPLCAAAAGLAGAVPVPYPLDE 212
Cdd:TIGR01265  81 AVAEYLSSDLPGK-----LTADDVVLTSGCSQAIEICIEALANPGA----NILVPRPGFPLYDTRAAFSGLEVRLYDLLP 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 213 SRGWAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFsPERPFLSFk 292
Cdd:TIGR01265 152 EKDWEIDLDGLESLADE-----KTVAIVVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVF-GDAPFIPM- 224

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1799935025 293 rvlaelgAPLATSVQLVSFYSLSKGIGGGGFRAGFLeLVNIERSVLRGFYTWGL 346
Cdd:TIGR01265 225 -------ASFASIVPVLSLGGISKRWVVPGWRLGWI-IIHDPHGIFRDTVLQGL 270
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
 151-262 7.23e-06

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 47.82  E-value: 7.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 151 CDPANIVPCAGTAAAVVDVLSLVVCPGSAlptgVLVPVPG---PPLCAAAAGLagaVPVPYPLDESrgWAVDVAALRREV 227
Cdd:COG0079    63 VPPEQVLVGNGSDELIQLLARAFLGPGDE----VLVPEPTfseYPIAARAAGA---EVVEVPLDED--FSLDLDALLAAI 133

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1799935025 228 REarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVR 262
Cdd:COG0079   134 TE-----RTDLVFLCNPNNPTGTLLPREELEALLE 163
PLN02607 PLN02607
1-aminocyclopropane-1-carboxylate synthase
 152-326 7.85e-06

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 215327 [Multi-domain]  Cd Length: 447  Bit Score: 47.96  E-value: 7.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 152 DPANIVPCAGTAAAVVDVLSLVVCPGSALptgvLVPVPGPPLCAAAAGLAGAVP-VPYPLDESRGWAVDVAALRREVREA 230
Cdd:PLN02607  119 DPDRIVLTAGATAANELLTFILADPGDAL----LVPTPYYPGFDRDLRWRTGVKiVPIHCDSSNNFQVTPQALEAAYQEA 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 231 RSR-CHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAF-SPErpFLSFKRVLAELGAP-LATSVQ 307
Cdd:PLN02607  195 EAAnIRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSGSVFsASE--FVSVAEIVEARGYKgVAERVH 272

                         170
                  ....*....|....*....
gi 1799935025 308 LVsfYSLSKGIGGGGFRAG 326
Cdd:PLN02607  273 IV--YSLSKDLGLPGFRVG 289
PLN00145 PLN00145
tyrosine/nicotianamine aminotransferase; Provisional
 123-289 1.71e-05

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 215074 [Multi-domain]  Cd Length: 430  Bit Score: 46.69  E-value: 1.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 123 GAYNlEYVTGAVAERAARFLAH---RDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSalptGVLVPVPGPPLCAAAAG 199
Cdd:PLN00145   85 GKYN-SYSTCVGLLPARRAIAEylsRDLPYELSTDDIYLTAGCAQAIEIIMSVLAQPGA----NILLPRPGYPLYEARAV 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 200 LAGAVPVPYPLDESRGWAVDVAALrrevrEARSRCHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQE 279
Cdd:PLN00145  160 FSGLEVRHFDLLPERGWEVDLEGV-----EALADENTVAMVIINPNNPCGSVYSYEHLAKIAETARKLGILVIADEVYDH 234

                         170
                  ....*....|
gi 1799935025 280 RAFSpERPFL 289
Cdd:PLN00145  235 LTFG-SKPFV 243
PRK05764 PRK05764
aspartate aminotransferase; Provisional
 144-262 2.51e-05

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 46.27  E-value: 2.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 144 HRDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSAlptgVLVPVPG----PP---LCAAaaglagaVPVPYPLDESRGW 216
Cdd:PRK05764   82 KRDNGLDYDPSQVIVTTGAKQALYNAFMALLDPGDE----VIIPAPYwvsyPEmvkLAGG-------VPVFVPTGEENGF 150

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1799935025 217 AVDVAALRrevrEARSrchPRVLWVV--NPGDPTGHVLSRPDMESIVR 262
Cdd:PRK05764  151 KLTVEQLE----AAIT---PKTKALIlnSPSNPTGAVYSPEELEAIAD 191
PTZ00433 PTZ00433
tyrosine aminotransferase; Provisional
 141-414 9.42e-05

tyrosine aminotransferase; Provisional


Pssm-ID: 185613  Cd Length: 412  Bit Score: 44.39  E-value: 9.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 141 FLAHRDRGIACDPANIVPCAGTAAAvvdvlsLVVCPGSALPTG--VLVPVPGPP----LCAAAAGLAGAvpvpYPLDESR 214
Cdd:PTZ00433   92 FVHKESLKSTIKKDNVVLCSGVSHA------ILMALTALCDEGdnILVPAPGFPhyetVCKAYGIEMRF----YNCRPEK 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 215 GWAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPErpflSFKRV 294
Cdd:PTZ00433  162 DWEADLDEIRRLVDD-----RTKALIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGA----TFTSV 232

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 295 laelgAPLATSVQLVSFYSLSKGIGGGGFRAGFLELV---NIERSVLRGFYTWGLSVYPP--ILGQVMLDVAMEPPghrd 369
Cdd:PTZ00433  233 -----ADFDTTVPRVILGGTAKNLVVPGWRLGWLLLVdphGNGGDFLDGMKRLGMLVCGPcsVVQAALGEALLNTP---- 303

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1799935025 370 pasaamEEHRRDLCRDLAANARRLQEELGRAPGIRCQPlaggPRA 414
Cdd:PTZ00433  304 ------QEHLEQIVAKLEEGAMVLYNHIGECIGLSPTM----PRG 338
PRK09265 PRK09265
aminotransferase AlaT; Validated
 184-328 1.29e-04

aminotransferase AlaT; Validated


Pssm-ID: 181738  Cd Length: 404  Bit Score: 44.03  E-value: 1.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 184 VLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVrl 263
Cdd:PRK09265  122 VLVPAPDYPLWTAAVSLSGGKPVHYLCDEEAGWFPDLDDIRSKITP-----RTKAIVIINPNNPTGAVYSKELLEEIV-- 194

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1799935025 264 aaeeplllladEV---HQERAFSPErpflSFKRVLAELG-----APLATSVQLVSFYSLSKGIGGGGFRAGFL 328
Cdd:PRK09265  195 -----------EIarqHNLIIFADE----IYDKILYDGAvhisiASLAPDLLCVTFNGLSKAYRVAGFRVGWM 252
PRK06855 PRK06855
pyridoxal phosphate-dependent aminotransferase;
205-261 2.20e-04

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180734  Cd Length: 433  Bit Score: 43.40  E-value: 2.20e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1799935025 205 PVPYPLDESRGWAVDVAALRREVREarsrcHPRV--LWVVNPGDPTGHVLSRPDMESIV 261
Cdd:PRK06855  144 PVTYRLDPENNWYPDLDDLENKVKY-----NPSIagILLINPDNPTGAVYPKEILREIV 197
PLN00143 PLN00143
tyrosine/nicotianamine aminotransferase; Provisional
 131-328 2.38e-04

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 165711 [Multi-domain]  Cd Length: 409  Bit Score: 43.08  E-value: 2.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 131 TGAV--AERAARFLAHRDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSalptGVLVPVPGPPLCAAAAGLAGAVPVPY 208
Cdd:PLN00143   73 TGGIlpARRAIADYLSNDLPYQLSPDDVYLTLGCKHAAEIIIKVLARPEA----NILLPRPGFPDVETYAIFHHLEIRHF 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 209 PLDESRGWAVDVAALrrevrEARSRCHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSpERPF 288
Cdd:PLN00143  149 DLLPEKGWEVDLDAV-----EAIADENTIAMVIINPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFG-SKPF 222

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1799935025 289 LSFkrvlaelgAPLATSVQLVSFYSLSKGIGGGGFRAGFL 328
Cdd:PLN00143  223 VPM--------GLFASIVPVITLGSISKRWMIPGWGLGWL 254
PRK07777 PRK07777
putative succinyldiaminopimelate transaminase DapC;
100-282 3.81e-04

putative succinyldiaminopimelate transaminase DapC;


Pssm-ID: 236095 [Multi-domain]  Cd Length: 387  Bit Score: 42.33  E-value: 3.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 100 EDIPESAKEHARRILRELMGGSPGAYNLEYVTGAVAeraarflAHRDR--GIACDPAN--IVPCAGTAAAVVDVLSLVVc 175
Cdd:PRK07777   36 EDGPPEMLEAAQEAIAGGVNQYPPGPGIPELRAAIA-------AQRRRryGLEYDPDTevLVTVGATEAIAAAVLGLVE- 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 176 PGS----------------ALPTGVLVPVPGPPlcaaaaglagavpvpypldESRGWAVDVAALRREVREarsrcHPRVL 239
Cdd:PRK07777  108 PGDevlliepyydsyaaviAMAGAHRVPVPLVP-------------------DGRGFALDLDALRAAVTP-----RTRAL 163

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1799935025 240 WVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAF 282
Cdd:PRK07777  164 IVNSPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVF 206
PLN02656 PLN02656
tyrosine transaminase
 133-289 1.21e-03

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 41.06  E-value: 1.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 133 AVAERAARFLAHRdrgIACDPANIVpcAGTAAAVVDVLSLVVCPGSalptGVLVPVPGPPLCAAAAGLAGAVPVPYPLDE 212
Cdd:PLN02656   81 AIAEYLSRDLPYK---LSLDDVFIT--SGCTQAIDVALSMLARPGA----NILLPRPGFPIYELCAAFRHLEVRYVDLLP 151

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1799935025 213 SRGWAVDVAALrrevrEARSRCHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSpERPFL 289
Cdd:PLN02656  152 EKGWEVDLDAV-----EALADQNTVALVIINPGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFG-SNPFV 222
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
139-430 1.31e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 40.70  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 139 ARFLAhRDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSAlptgVLVPVPGPPLCAAAAGLAGAVPVPYPLD-ESRGWA 217
Cdd:PRK06108   71 ARYVS-RLHGVATPPERIAVTSSGVQALMLAAQALVGPGDE----VVAVTPLWPNLVAAPKILGARVVCVPLDfGGGGWT 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 218 VDVAALRREVREArsrchPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAFSPERPFLSFKRVLAE 297
Cdd:PRK06108  146 LDLDRLLAAITPR-----TRALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGGRAPSFLDIAEP 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 298 lgaplatSVQLVSFYSLSKGIGGGGFRAGFLELvniersvlrgfytwglsvyPPILGQVM-----LDVAMEPPGHRDPAS 372
Cdd:PRK06108  221 -------DDRIIFVNSFSKNWAMTGWRLGWLVA-------------------PPALGQVLeklieYNTSCVAQFVQRAAV 274

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1799935025 373 AAMEE---HRRDLCRDLAANARRLQEELGRAPGIRCQPLAGGPRAFPRIRIPPRARSQARA 430
Cdd:PRK06108  275 AALDEgedFVAELVARLRRSRDHLVDALRALPGVEVAKPDGAMYAFFRIPGVTDSLALAKR 335
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 184-330 1.37e-03

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 40.88  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 184 VLVPVPGPPLCAAAAGLAGAVPVPYPLDESRGWAVDVAALRREVreaRSRChpRVLWVVNPGDPTGHVLSRPDMESIVRL 263
Cdd:PRK13355  235 VLIPSPDYPLWTACVNLAGGTAVHYRCDEQSEWYPDIDDIRSKI---TSRT--KAIVIINPNNPTGALYPREVLQQIVDI 309

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1799935025 264 AAEeplllladevHQERAFSPErpflSFKRVLAElG------APLATSVQLVSFYSLSKGIGGGGFRAGFLEL 330
Cdd:PRK13355  310 ARE----------HQLIIFSDE----IYDRLVMD-GlehtsiASLAPDLFCVTFSGLSKSHMIAGYRIGWMIL 367
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 94-253 1.68e-03

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 40.58  E-value: 1.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025  94 PALLEHEDIPESAKEHARRILRELMGGSPGAynleyvtGAVAERAArfLAHR--DRGIACDPANIVPCAGTAAAVVDVLS 171
Cdd:COG1167   118 PDLFPLAALRRALRRALRRLPPALLGYGDPQ-------GLPELREA--IARYlaRRGVPASPDQILITSGAQQALDLALR 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 172 LVVCPGSAlptgVLVPVPGPPLCAAAAGLAGAVPVPYPLDEsRGWavDVAALRREVREARsrchPRVLWVV----NpgdP 247
Cdd:COG1167   189 ALLRPGDT----VAVESPTYPGALAALRAAGLRLVPVPVDE-DGL--DLDALEAALRRHR----PRAVYVTpshqN---P 254


                  ....*.
gi 1799935025 248 TGHVLS 253
Cdd:COG1167   255 TGATMS 260
PLN02450 PLN02450
1-aminocyclopropane-1-carboxylate synthase
 139-326 1.88e-03

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178069 [Multi-domain]  Cd Length: 468  Bit Score: 40.51  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 139 ARFLAH-RDRGIACDPANIVPCAGTAAAVVDVLSLVVCPGSALptgvLVPVPGPPLCAAAAGLAGAVP-VPYPLDESRGW 216
Cdd:PLN02450   96 AEFMSEiRGNKVTFDPNKLVLTAGATSANETLMFCLAEPGDAF----LLPTPYYPGFDRDLKWRTGVEiVPIHCSSSNGF 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 217 AVDVAALRREVREA-RSRCHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQERAF-SPErpFLSFKRV 294
Cdd:PLN02450  172 QITESALEEAYQQAqKLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFdSPG--FVSVMEV 249

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1799935025 295 LAEL---GAPLATSVQLVsfYSLSKGIGGGGFRAG 326
Cdd:PLN02450  250 LKDRkleNTDVSNRVHIV--YSLSKDLGLPGFRVG 282
PRK09147 PRK09147
succinyldiaminopimelate transaminase; Provisional
 139-327 2.31e-03

succinyldiaminopimelate transaminase; Provisional


Pssm-ID: 236393  Cd Length: 396  Bit Score: 39.86  E-value: 2.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 139 ARFLAHRDRGIACDPA-NIVPCAGT-------AAAVVDVLS---LVVCP--------GSALPTGVlvpvpgpplcaaaag 199
Cdd:PRK09147   75 AAWLERRYGLPALDPAtQVLPVNGSrealfafAQTVIDRDGpgpLVVCPnpfyqiyeGAALLAGA--------------- 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 200 lagaVPVPYPLDESRGWAVDVAALRREVREarsRChpRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHQE 279
Cdd:PRK09147  140 ----EPYFLNCDPANNFAPDFDAVPAEVWA---RT--QLLFVCSPGNPTGAVLPLDDWKKLFALSDRYGFVIASDECYSE 210

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1799935025 280 RAFSPERPFLSFKRVLAELGAPLATsvQLVSFYSLSKGIGGGGFRAGF 327
Cdd:PRK09147  211 IYFDEAAPPLGLLEAAAELGRDDFK--RLVVFHSLSKRSNVPGLRSGF 256
PRK07324 PRK07324
transaminase; Validated
 209-421 5.09e-03

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 38.77  E-value: 5.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 209 PLDESRGWAVDVAALRREVREarsrcHPRVLWVVNPGDPTGHVLSRPDMESIVRLAAEEPLLLLADEVHqeRAFSPERPF 288
Cdd:PRK07324  132 QLKEENGWLPDLDELRRLVRP-----NTKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVY--RPLDEDGST 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799935025 289 LSFKRvLAELGapLATSvqlvsfySLSKGIGGGGFRAGFL----ELVNIERSVlRGFYTWGLSVYPPILGQVMLDvamep 364
Cdd:PRK07324  205 PSIAD-LYEKG--ISTN-------SMSKTYSLPGIRVGWIaaneEVIDILRKY-RDYTMICAGVFDDMLASLALE----- 268

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1799935025 365 pgHRDpasaAMEEHRRDLCRDlaaNARRLQEELGRAPGIRCQPLAGGPRAFPRIRIP 421
Cdd:PRK07324  269 --HRD----AILERNRKIVRT---NLAILDEWVAKEPRVSYVKPKAVSTSFVKLDVD 316
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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