galectin-3-binding protein isoform X1 [Mus musculus]
galectin-3-binding protein( domain architecture ID 13895019)
galectin-3-binding protein (Lgals3bp) promotes integrin-mediated cell adhesion and may stimulate host defense against viruses and tumor cells
List of domain hits
Name | Accession | Description | Interval | E-value | |||
SR | smart00202 | Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
56-156 | 8.85e-47 | |||
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO. : Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 159.81 E-value: 8.85e-47
|
|||||||
BTB_POZ super family | cl38908 | BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain ... |
168-279 | 8.84e-46 | |||
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily; Proteins in this superfamily are characterized by the presence of a common protein-protein interaction motif of about 100 amino acids, known as the BTB/POZ domain. Members include transcription factors, oncogenic proteins, ion channel proteins, and potassium channel tetramerization domain (KCTD) proteins. They have been identified in poxviruses and many eukaryotes, and have diverse functions, such as transcriptional regulation, chromatin remodeling, protein degradation and cytoskeletal regulation. Many BTB/POZ proteins contain one or two additional domains, such as kelch repeats, zinc-finger domains, FYVE (Fab1, YOTB, Vac1, and EEA1) fingers, or ankyrin repeats, among others. These special additional domains or interaction partners provide unique characteristics and functions to BTB/POZ proteins. In ion channel proteins and KCTD proteins, the BTB/POZ domain is also called the tetramerization (T1) domain. The actual alignment was detected with superfamily member cd18304: Pssm-ID: 453885 [Multi-domain] Cd Length: 114 Bit Score: 157.26 E-value: 8.84e-46
|
|||||||
BACK super family | cl28903 | BACK (BTB and C-terminal Kelch) domain; The BACK domain is found in architectures C-terminal ... |
288-361 | 1.65e-26 | |||
BACK (BTB and C-terminal Kelch) domain; The BACK domain is found in architectures C-terminal to a BTB domain, in a diverse set of architectures together with Kelch, MATH, and/or TAZ domains. It is involved in interactions with the Cullin3 (Cul3) ubiquitin ligase complex, as well as in homo-oligomerization. Most proteins containing the BACK domain are understood to function as adaptor proteins that play a role in ubiquitination of various substrates. The actual alignment was detected with superfamily member cd18496: Pssm-ID: 475122 Cd Length: 74 Bit Score: 102.86 E-value: 1.65e-26
|
|||||||
Name | Accession | Description | Interval | E-value | |||
SR | smart00202 | Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
56-156 | 8.85e-47 | |||
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO. Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 159.81 E-value: 8.85e-47
|
|||||||
BTB_POZ_M2BP | cd18304 | BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in ... |
168-279 | 8.84e-46 | |||
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Mac-2-binding protein (MAC2BP/M2BP); M2BP is also called galectin-3-binding protein, basement membrane autoantigen p105, lectin galactoside-binding soluble 3-binding protein (LGALS3BP), or tumor-associated antigen 90K. It promotes integrin-mediated cell adhesion and may stimulate host defense against viruses and tumor cells. It contains a scavenger receptor cysteine-rich domain, followed by BTB and BACK domains. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids. Pssm-ID: 349613 [Multi-domain] Cd Length: 114 Bit Score: 157.26 E-value: 8.84e-46
|
|||||||
SRCR | pfam00530 | Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
61-156 | 3.32e-40 | |||
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions. Pssm-ID: 459844 Cd Length: 98 Bit Score: 141.74 E-value: 3.32e-40
|
|||||||
BACK_LGALS3BP | cd18496 | BACK (BTB and C-terminal Kelch) domain found in lectin galactoside-binding soluble 3-binding ... |
288-361 | 1.65e-26 | |||
BACK (BTB and C-terminal Kelch) domain found in lectin galactoside-binding soluble 3-binding protein (LGALS3BP); LGALS3BP, also called galectin-3-binding protein, or basement membrane autoantigen p105, or Mac-2-binding protein (MAC2BP/M2BP), or tumor-associated antigen 90K, promotes integrin-mediated cell adhesion. It may stimulate host defense against viruses and tumor cells. Pssm-ID: 350571 Cd Length: 74 Bit Score: 102.86 E-value: 1.65e-26
|
|||||||
BACK | smart00875 | BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are ... |
293-390 | 9.69e-19 | |||
BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues. Pssm-ID: 197943 [Multi-domain] Cd Length: 101 Bit Score: 81.62 E-value: 9.69e-19
|
|||||||
BACK | pfam07707 | BTB And C-terminal Kelch; This domain is found associated with pfam00651 and pfam01344. The ... |
293-391 | 1.53e-11 | |||
BTB And C-terminal Kelch; This domain is found associated with pfam00651 and pfam01344. The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues. This family appears to be closely related to the BTB domain (Finn RD, personal observation). Pssm-ID: 462237 [Multi-domain] Cd Length: 103 Bit Score: 61.02 E-value: 1.53e-11
|
|||||||
BTB | smart00225 | Broad-Complex, Tramtrack and Bric a brac; Domain in Broad-Complex, Tramtrack and Bric a brac. ... |
235-283 | 1.10e-03 | |||
Broad-Complex, Tramtrack and Bric a brac; Domain in Broad-Complex, Tramtrack and Bric a brac. Also known as POZ (poxvirus and zinc finger) domain. Known to be a protein-protein interaction motif found at the N-termini of several C2H2-type transcription factors as well as Shaw-type potassium channels. Known structure reveals a tightly intertwined dimer formed via interactions between N-terminal strand and helix structures. However in a subset of BTB/POZ domains, these two secondary structures appear to be missing. Be aware SMART predicts BTB/POZ domains without the beta1- and alpha1-secondary structures. Pssm-ID: 197585 [Multi-domain] Cd Length: 97 Bit Score: 38.44 E-value: 1.10e-03
|
|||||||
Name | Accession | Description | Interval | E-value | |||
SR | smart00202 | Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
56-156 | 8.85e-47 | |||
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO. Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 159.81 E-value: 8.85e-47
|
|||||||
BTB_POZ_M2BP | cd18304 | BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in ... |
168-279 | 8.84e-46 | |||
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Mac-2-binding protein (MAC2BP/M2BP); M2BP is also called galectin-3-binding protein, basement membrane autoantigen p105, lectin galactoside-binding soluble 3-binding protein (LGALS3BP), or tumor-associated antigen 90K. It promotes integrin-mediated cell adhesion and may stimulate host defense against viruses and tumor cells. It contains a scavenger receptor cysteine-rich domain, followed by BTB and BACK domains. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids. Pssm-ID: 349613 [Multi-domain] Cd Length: 114 Bit Score: 157.26 E-value: 8.84e-46
|
|||||||
SRCR | pfam00530 | Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
61-156 | 3.32e-40 | |||
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions. Pssm-ID: 459844 Cd Length: 98 Bit Score: 141.74 E-value: 3.32e-40
|
|||||||
BACK_LGALS3BP | cd18496 | BACK (BTB and C-terminal Kelch) domain found in lectin galactoside-binding soluble 3-binding ... |
288-361 | 1.65e-26 | |||
BACK (BTB and C-terminal Kelch) domain found in lectin galactoside-binding soluble 3-binding protein (LGALS3BP); LGALS3BP, also called galectin-3-binding protein, or basement membrane autoantigen p105, or Mac-2-binding protein (MAC2BP/M2BP), or tumor-associated antigen 90K, promotes integrin-mediated cell adhesion. It may stimulate host defense against viruses and tumor cells. Pssm-ID: 350571 Cd Length: 74 Bit Score: 102.86 E-value: 1.65e-26
|
|||||||
BACK | smart00875 | BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are ... |
293-390 | 9.69e-19 | |||
BTB And C-terminal Kelch; The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues. Pssm-ID: 197943 [Multi-domain] Cd Length: 101 Bit Score: 81.62 E-value: 9.69e-19
|
|||||||
BACK_BTBD17 | cd18493 | BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 17 (BTBD17); ... |
296-360 | 2.68e-13 | |||
BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 17 (BTBD17); BTBD17, also termed galectin-3-binding protein-like, is a BTB-domain-containing Kelch-like protein. Its function remains unclear. It may be involved in hepatocellular carcinoma development and progression. Pssm-ID: 350568 Cd Length: 74 Bit Score: 65.29 E-value: 2.68e-13
|
|||||||
BACK | pfam07707 | BTB And C-terminal Kelch; This domain is found associated with pfam00651 and pfam01344. The ... |
293-391 | 1.53e-11 | |||
BTB And C-terminal Kelch; This domain is found associated with pfam00651 and pfam01344. The BACK domain is found juxtaposed to the BTB domain; they are separated by as little as two residues. This family appears to be closely related to the BTB domain (Finn RD, personal observation). Pssm-ID: 462237 [Multi-domain] Cd Length: 103 Bit Score: 61.02 E-value: 1.53e-11
|
|||||||
BTB_POZ_BTBD17 | cd18292 | BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in ... |
175-275 | 1.24e-09 | |||
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 17 (BTBD17); BTBD17, also called galectin-3-binding protein-like, is a BTB domain-containing protein. Its function remains unclear. It may be associated with hepatocellular carcinoma. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids. Pssm-ID: 349601 [Multi-domain] Cd Length: 114 Bit Score: 56.14 E-value: 1.24e-09
|
|||||||
BACK_KBTBD3 | cd18480 | BACK (BTB and C-terminal Kelch) domain found in Kelch repeat and BTB domain-containing protein ... |
293-360 | 1.42e-04 | |||
BACK (BTB and C-terminal Kelch) domain found in Kelch repeat and BTB domain-containing protein 3 (KBTBD3); KBTBD3, also termed BTB and kelch domain-containing protein 3 (BKLHD3), is a BTB-Kelch family protein. Its function remains unclear. Pssm-ID: 350555 [Multi-domain] Cd Length: 82 Bit Score: 40.77 E-value: 1.42e-04
|
|||||||
BACK_KLHL22 | cd18461 | BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 22 (KLHL22); KLHL22 is a ... |
293-383 | 3.82e-04 | |||
BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 22 (KLHL22); KLHL22 is a substrate-specific adaptor of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of Polo-like kinase 1 (PLK1) at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Pssm-ID: 350536 Cd Length: 104 Bit Score: 40.13 E-value: 3.82e-04
|
|||||||
BTB_POZ_RCBTB1_2 | cd18298 | BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in ... |
173-278 | 6.84e-04 | |||
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing proteins, RCBTB1 and RCBTB2; The RCC1-related guanine nucleotide exchange factor (GEF) family includes RCC1 and BTB domain-containing proteins, RCBTB1 and RCBTB2, both of which are chromosome condensation regulator-like guanine nucleotide exchange factors. They contain an RCC1 repeat, a BTB domain, and a BACK domain. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids. Pssm-ID: 349607 [Multi-domain] Cd Length: 108 Bit Score: 39.54 E-value: 6.84e-04
|
|||||||
BACK | cd14733 | BACK (BTB and C-terminal Kelch) domain; The BACK domain is found in architectures C-terminal ... |
293-340 | 8.51e-04 | |||
BACK (BTB and C-terminal Kelch) domain; The BACK domain is found in architectures C-terminal to a BTB domain, in a diverse set of architectures together with Kelch, MATH, and/or TAZ domains. It is involved in interactions with the Cullin3 (Cul3) ubiquitin ligase complex, as well as in homo-oligomerization. Most proteins containing the BACK domain are understood to function as adaptor proteins that play a role in ubiquitination of various substrates. Pssm-ID: 350515 [Multi-domain] Cd Length: 55 Bit Score: 37.64 E-value: 8.51e-04
|
|||||||
BTB | smart00225 | Broad-Complex, Tramtrack and Bric a brac; Domain in Broad-Complex, Tramtrack and Bric a brac. ... |
235-283 | 1.10e-03 | |||
Broad-Complex, Tramtrack and Bric a brac; Domain in Broad-Complex, Tramtrack and Bric a brac. Also known as POZ (poxvirus and zinc finger) domain. Known to be a protein-protein interaction motif found at the N-termini of several C2H2-type transcription factors as well as Shaw-type potassium channels. Known structure reveals a tightly intertwined dimer formed via interactions between N-terminal strand and helix structures. However in a subset of BTB/POZ domains, these two secondary structures appear to be missing. Be aware SMART predicts BTB/POZ domains without the beta1- and alpha1-secondary structures. Pssm-ID: 197585 [Multi-domain] Cd Length: 97 Bit Score: 38.44 E-value: 1.10e-03
|
|||||||
BACK_KLHL18 | cd18457 | BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 18 (KLHL18); KLHL18 acts as ... |
305-388 | 2.91e-03 | |||
BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 18 (KLHL18); KLHL18 acts as a substrate-specific adaptor for the Cullin3 E3 ubiquitin-protein ligase complex that regulates mitotic entry and ubiquitylates Aurora-A. Pssm-ID: 350532 [Multi-domain] Cd Length: 107 Bit Score: 37.67 E-value: 2.91e-03
|
|||||||
BACK_KLHL33 | cd18472 | BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 33 (KLHL33); KLHL33 belongs ... |
293-360 | 7.79e-03 | |||
BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 33 (KLHL33); KLHL33 belongs to the KLHL family. Its function remains unclear. KLHL33 SNPs may be associated with prostate cancer risk. Pssm-ID: 350547 [Multi-domain] Cd Length: 75 Bit Score: 35.44 E-value: 7.79e-03
|
|||||||
Blast search parameters | ||||
|