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Conserved domains on  [gi|1907080650|ref|XP_036012355|]
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nuclear receptor corepressor 1 isoform X10 [Mus musculus]

Protein Classification

nuclear receptor corepressor 1( domain architecture ID 15502538)

nuclear receptor corepressor 1 (NCOR1) is a transcriptional coregulatory protein which assists nuclear receptors in the down regulation of gene expression

CATH:  1.20.58.1880
Gene Ontology:  GO:0006355|GO:0003700|GO:0003677
PubMed:  8882580|20084085
SCOP:  4000317

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GPS2_interact super family cl24372
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 9.67e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


The actual alignment was detected with superfamily member pfam15784:

Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 105.71  E-value: 9.67e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1907080650  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 627-670 6.35e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.35e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1907080650  627 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 670
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
MDN1 super family cl34967
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 711-910 8.67e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG5271:

Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 51.55  E-value: 8.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  711 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 784
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  785 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 863
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907080650  864 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 910
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 441-483 1.31e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.31e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1907080650  441 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 483
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 9.67e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 105.71  E-value: 9.67e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1907080650  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 627-670 6.35e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.35e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1907080650  627 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 670
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 627-670 1.37e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.36  E-value: 1.37e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1907080650  627 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYK 670
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
627-672 2.19e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 2.19e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1907080650   627 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYKRR 672
Cdd:smart00717    3 EWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 711-910 8.67e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 51.55  E-value: 8.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  711 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 784
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  785 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 863
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907080650  864 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 910
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 745-910 7.68e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 47.67  E-value: 7.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  745 EAAKSSEDSSENAASRGNTEPVAELEATT--DPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEEcGAE 822
Cdd:PRK13108   283 GALRGSEYVVDEALEREPAELAAAAVASAasAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGE-STP 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  823 GSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKErDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSADEGV 902
Cdd:PRK13108   362 AVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAA-PEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDD 440


                   ....*...
gi 1907080650  903 DGEPERQR 910
Cdd:PRK13108   441 PAEPDGIR 448
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 441-483 1.31e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.31e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1907080650  441 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 483
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
439-484 4.05e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.28  E-value: 4.05e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1907080650   439 NVWTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTKK 484
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 441-480 5.38e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 39.79  E-value: 5.38e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907080650  441 WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYY 480
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 683-905 7.32e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.90  E-value: 7.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  683 KQKASRKP---------REERDVSQCESVAStvSAQEDEDIEASNEEENPEDSEG-AENSSDTES---APSPSPVEAAKS 749
Cdd:TIGR00927  613 KEQLSRRPvakvmalgdLSKGDVAEAEHTGE--RTGEEGERPTEAEGENGEESGGeAEQEGETETkgeNESEGEIPAERK 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  750 SEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDP 829
Cdd:TIGR00927  691 GEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGET 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  830 PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSAD---------E 900
Cdd:TIGR00927  771 EAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAEnqgeakqdeK 850


                   ....*
gi 1907080650  901 GVDGE 905
Cdd:TIGR00927  851 GVDGG 855
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 9.67e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 105.71  E-value: 9.67e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1907080650  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 627-670 6.35e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.35e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1907080650  627 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 670
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 627-670 1.37e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.36  E-value: 1.37e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1907080650  627 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYK 670
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
627-672 2.19e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 2.19e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1907080650   627 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYKRR 672
Cdd:smart00717    3 EWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 711-910 8.67e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 51.55  E-value: 8.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  711 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 784
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  785 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 863
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907080650  864 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 910
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 686-905 4.61e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 48.86  E-value: 4.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  686 ASRKPREERDVSQCESVASTVSAQEDEDIEAS-----NEEENPEDSEGAENSSDTE------SAPSPSPVEAAKSSEDSS 754
Cdd:COG5271    525 AADPEDSDEDALEDETEGEENAPGSDQDADETdepeaTAEEDEPDEAEAETEDATEnadadeTEESADESEEAEASEDEA 604

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  755 ENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKP------AERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVL- 827
Cdd:COG5271    605 AEEEEADDDEADADADGAADEEETEEEAAEDEAAEPetdaseAADEDADAETEAEASADESEEEAEDESETSSEDAEEDa 684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  828 -DPPAPTKADSVDPEM---------QVPENTASKGEGDAKERDLESTSEKTEARDE---------DVVVAEQIERPEPQS 888
Cdd:COG5271    685 dAAAAEASDDEEETEEadedaetasEEADAEEADTEADGTAEEAEEAAEEAESADEeaaslpdeaDAEEEAEEAEEAEED 764

                          250
                   ....*....|....*..
gi 1907080650  889 DDDSSATCSADEGVDGE 905
Cdd:COG5271    765 DADGLEEALEEEKADAE 781
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 745-910 7.68e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 47.67  E-value: 7.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  745 EAAKSSEDSSENAASRGNTEPVAELEATT--DPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEEcGAE 822
Cdd:PRK13108   283 GALRGSEYVVDEALEREPAELAAAAVASAasAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGE-STP 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  823 GSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKErDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSADEGV 902
Cdd:PRK13108   362 AVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAA-PEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDD 440


                   ....*...
gi 1907080650  903 DGEPERQR 910
Cdd:PRK13108   441 PAEPDGIR 448
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 441-483 1.31e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.31e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1907080650  441 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 483
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 700-907 2.85e-04

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 46.55  E-value: 2.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  700 ESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPApcA 779
Cdd:COG5271    561 ATAEEDEPDEAEAETEDATENADADETEESADESEEAEASEDEAAEEEEADDDEADADADGAADEEETEEEAAEDEA--A 638

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  780 SPSSAVPTtkpAERESVEAQVTDSASAETAEPMDVDHEEcgaegssVLDPPAPTKADSVDPEMQVPENTASKGEGDAKER 859
Cdd:COG5271    639 EPETDASE---AADEDADAETEAEASADESEEEAEDESE-------TSSEDAEEDADAAAAEASDDEEETEEADEDAETA 708

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1907080650  860 DLESTSEKTEArDEDVVVAEQIERPEPQSDDDSSATcSADEGVDGEPE 907
Cdd:COG5271    709 SEEADAEEADT-EADGTAEEAEEAAEEAESADEEAA-SLPDEADAEEE 754
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 714-870 3.69e-04

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 45.74  E-value: 3.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  714 IEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNT------------EPVAELEATTDPAPCASP 781
Cdd:PRK13108   273 ILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGPGEpnqpddvaeavkAEVAEVTDEVAAESVVQV 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  782 SSAVPTTKPAERESVEAQVTDSASAET-AEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASKGEGDakeRD 860
Cdd:PRK13108   353 ADRDGESTPAVEETSEADIEREQPGDLaGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPA---KP 429

                          170
                   ....*....|
gi 1907080650  861 LESTSEKTEA 870
Cdd:PRK13108   430 DELAVAGPGD 439
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
439-484 4.05e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.28  E-value: 4.05e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1907080650   439 NVWTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTKK 484
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 441-480 5.38e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 39.79  E-value: 5.38e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907080650  441 WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYY 480
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 683-858 6.85e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 45.08  E-value: 6.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  683 KQKASRKPREERDVSQCESVASTVSAQ----EDEDIEASNEEENPEDSEGAENSSDTESAPSPSP-----VEAAKSSEDS 753
Cdd:PRK08691   387 KETAAKKPQPRPEAETAQTPVQTASAAampsEGKTAGPVSNQENNDVPPWEDAPDEAQTAAGTAQtsaksIQTASEAETP 466

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  754 SENAASRgNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEgssvlDPPAPT 833
Cdd:PRK08691   467 PENQVSK-NKAADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAEPFYGYGFPDNDCPPEDGAE-----IPPPDW 540

                          170       180
                   ....*....|....*....|....*
gi 1907080650  834 kadsvdpEMQVPENTASKGEGDAKE 858
Cdd:PRK08691   541 -------EHAAPADTAGGGADEEAE 558
SANT_MTA3_like cd11661
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ...
 441-484 9.92e-04

Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.


Pssm-ID: 212559 [Multi-domain]  Cd Length: 46  Bit Score: 39.13  E-value: 9.92e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1907080650  441 WTDHEKEIFKDKFIQHPKNFGLI-ASYLERKSVPDCVLYYYLTKK 484
Cdd:cd11661      2 WSESEAKLFEEGLRKYGKDFHDIrQDFLPWKSVGELVEFYYMWKK 46
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 726-926 1.04e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.78  E-value: 1.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  726 SEGAENSSDTESAPSPSPVEAAKSSEDSS----------------ENAASRGNTEPVAELEATTDPAPCA-SPSSAVPTT 788
Cdd:PHA03307    58 GAAACDRFEPPTGPPPGPGTEAPANESRStptwslstlapasparEGSPTPPGPSSPDPPPPTPPPASPPpSPAPDLSEM 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  789 KPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENT-ASKGEGDAKERDLESTSek 867
Cdd:PHA03307   138 LRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTpPAAASPRPPRRSSPISA-- 215

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907080650  868 tEARDEDVVVAEQIERPEPQSDDDSSATCSADEGVDGEPERQRvfPMDAKPSLLTPPGS 926
Cdd:PHA03307   216 -SASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL--PRPAPITLPTRIWE 271
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 705-907 1.78e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 43.85  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  705 TVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPCASPSSA 784
Cdd:COG5271    266 GTPDTDDEATDDADGLEAAEDDALDAELTAAQAADPESDDDADDSTLAALEGAAEDTEIATADELAAADDEDDDDSAAED 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  785 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKERDLEST 864
Cdd:COG5271    346 AAEEAATAEDSAAEDTQDAEDEAAGEAADESEGADTDAAADEADAAADDSADDEEASADGGTSPTSDTDEEEEEADEDAS 425

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1907080650  865 SEKTEARDEDVVVAEQIErpepqsDDDSSATCSADEGVDGEPE 907
Cdd:COG5271    426 AGETEDESTDVTSAEDDI------ATDEEADSLADEEEEAEAE 462
PHA03169 PHA03169
hypothetical protein; Provisional
 683-874 2.82e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 42.65  E-value: 2.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  683 KQKASRKPREERDVS-----QCESVASTVSAQEDEDIEASNEE---ENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSS 754
Cdd:PHA03169    37 RGTAARAAKPAPPAPttsgpQVRAVAEQGHRQTESDTETAEESrhgEKEERGQGGPSGSGSESVGSPTPSPSGSAEELAS 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  755 ----ENAASRGNTEPVAELEATTDPAPCASPSSAVPTT---KPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVL 827
Cdd:PHA03169   117 glspENTSGSSPESPASHSPPPSPPSHPGPHEPAPPEShnpSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSE 196

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1907080650  828 DP-PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDED 874
Cdd:PHA03169   197 TPtSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREG 244
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 628-675 3.22e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 38.06  E-value: 3.22e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1907080650  628 WTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKnFYFNYKRRHNL 675
Cdd:pfam13921    1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCF-DRWRRKLNPKI 47
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 744-907 3.73e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 42.27  E-value: 3.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  744 VEAAKSSEDSsenAASRGNtEPVAELEATTDPAPCA-----SPSSAVPTTKPAEresvEAQVTDSASAETAEPMDVDHEE 818
Cdd:PRK13108   273 ILAPKGREAP---GALRGS-EYVVDEALEREPAELAaaavaSAASAVGPVGPGE----PNQPDDVAEAVKAEVAEVTDEV 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  819 CGAEGSSVLD-----PPAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSS 893
Cdd:PRK13108   345 AAESVVQVADrdgesTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIP 424

                          170
                   ....*....|....
gi 1907080650  894 ATCSADEGVDGEPE 907
Cdd:PRK13108   425 DPAKPDELAVAGPG 438
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 707-907 5.61e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 42.31  E-value: 5.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  707 SAQEDEDIEASNEEENPED---------SEGAENSSDTEsapspSPVEAAKSSEDSSENAASRGNTEpvaelEATTDPAP 777
Cdd:COG5271    645 SEAADEDADAETEAEASADeseeeaedeSETSSEDAEED-----ADAAAAEASDDEEETEEADEDAE-----TASEEADA 714

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  778 CASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDppAPTKADSVDPEMQVPENTASKGEGDAK 857
Cdd:COG5271    715 EEADTEADGTAEEAEEAAEEAESADEEAASLPDEADAEEEAEEAEEAEEDD--ADGLEEALEEEKADAEEAATDEEAEAA 792

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907080650  858 ERDLESTSEKTEARDEDVVVAEQIE--------RPEPQSDDDSSATCSADEGVDGEPE 907
Cdd:COG5271    793 AEEKEKVADEDQDTDEDALLDEAEAdeeedldgEDEETADEALEDIEAGIAEDDEEDD 850
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 683-905 7.32e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.90  E-value: 7.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  683 KQKASRKP---------REERDVSQCESVAStvSAQEDEDIEASNEEENPEDSEG-AENSSDTES---APSPSPVEAAKS 749
Cdd:TIGR00927  613 KEQLSRRPvakvmalgdLSKGDVAEAEHTGE--RTGEEGERPTEAEGENGEESGGeAEQEGETETkgeNESEGEIPAERK 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  750 SEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDP 829
Cdd:TIGR00927  691 GEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGET 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  830 PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSAD---------E 900
Cdd:TIGR00927  771 EAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAEnqgeakqdeK 850


                   ....*
gi 1907080650  901 GVDGE 905
Cdd:TIGR00927  851 GVDGG 855
rne PRK10811
ribonuclease E; Reviewed
 692-851 7.93e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.56  E-value: 7.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  692 EERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEA 771
Cdd:PRK10811   854 QVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITE 933

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  772 TTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASK 851
Cdd:PRK10811   934 SDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEH 1013
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 710-908 8.92e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 41.54  E-value: 8.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  710 EDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVpttK 789
Cdd:COG5271    514 TSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADETEE---S 590

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907080650  790 PAERESVEAQVTDSASAETAEPMDVDheecgAEGSSVLDppaptKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTE 869
Cdd:COG5271    591 ADESEEAEASEDEAAEEEEADDDEAD-----ADADGAAD-----EEETEEEAAEDEAAEPETDASEAADEDADAETEAEA 660

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1907080650  870 ARDEDVV-VAEQIERPEPQSDDDSSATcSADEGVDGEPER 908
Cdd:COG5271    661 SADESEEeAEDESETSSEDAEEDADAA-AAEASDDEEETE 699
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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