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Conserved domains on  [gi|1958658762|ref|XP_038941984|]
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U3 small nucleolar RNA-associated protein 18 homolog isoform X1 [Rattus norvegicus]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
232-540 4.26e-31

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 125.02  E-value: 4.26e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 232 RPANAERPTTARISSVQFHPGAQVVMVSGVDHAISLFQVDgkTNPKIQSIYLEKFPIFKACFSANGeEVLATSMHSKVIY 311
Cdd:COG2319   111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLA--TGKLLRTLTGHSGAVTSVAFSPDG-KLLASGSDDGTVR 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 312 VYDMIAGKLIpvHQVRGlKEKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKI-NGRISASTFSSDSKRIYTS 390
Cdd:COG2319   188 LWDLATGKLL--RTLTG-HTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPDGRLLASG 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 391 SGNGEVYVWDVNSRKCInRFLDEGSLYGLSIAASKNGQYVACGSKSGVVNIYNQDSclqqtnPKPIKAIMNLVTGVTSLA 470
Cdd:COG2319   265 SADGTVRLWDLATGELL-RTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLAT------GKLLRTLTGHTGAVRSVA 337

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 471 FNPTTEILAVASRkmKEAVRLVHLPSCTVFSNFPVYKkstlSRVQTMDFSPRGGYFALGNEQGKALLYRL 540
Cdd:COG2319   338 FSPDGKTLASGSD--DGTVRLWDLATGELLRTLTGHT----GAVTSVAFSPDGRTLASGSADGTVRLWDL 401
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
232-540 4.26e-31

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 125.02  E-value: 4.26e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 232 RPANAERPTTARISSVQFHPGAQVVMVSGVDHAISLFQVDgkTNPKIQSIYLEKFPIFKACFSANGeEVLATSMHSKVIY 311
Cdd:COG2319   111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLA--TGKLLRTLTGHSGAVTSVAFSPDG-KLLASGSDDGTVR 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 312 VYDMIAGKLIpvHQVRGlKEKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKI-NGRISASTFSSDSKRIYTS 390
Cdd:COG2319   188 LWDLATGKLL--RTLTG-HTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPDGRLLASG 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 391 SGNGEVYVWDVNSRKCInRFLDEGSLYGLSIAASKNGQYVACGSKSGVVNIYNQDSclqqtnPKPIKAIMNLVTGVTSLA 470
Cdd:COG2319   265 SADGTVRLWDLATGELL-RTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLAT------GKLLRTLTGHTGAVRSVA 337

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 471 FNPTTEILAVASRkmKEAVRLVHLPSCTVFSNFPVYKkstlSRVQTMDFSPRGGYFALGNEQGKALLYRL 540
Cdd:COG2319   338 FSPDGKTLASGSD--DGTVRLWDLATGELLRTLTGHT----GAVTSVAFSPDGRTLASGSADGTVRLWDL 401
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 244-482 1.96e-20

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 91.63  E-value: 1.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 244 ISSVQFHPGAQVVMVSGVDHAISLFqvDGKTNPKIQSIYLEKFPIFKACFSANGEeVLATSMHSKVIYVYDMIAGKLIPV 323
Cdd:cd00200    54 VRDVAASADGTYLASGSSDKTIRLW--DLETGECVRTLTGHTSYVSSVAFSPDGR-ILSSSSRDKTIKVWDVETGKCLTT 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 324 hqVRGlKEKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKI-NGRISASTFSSDSKRIYTSSGNGEVYVWDVN 402
Cdd:cd00200   131 --LRG-HTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGhTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLS 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 403 SRKCINRFldEGSLYGL-SIAASKNGQYVACGSKSGVVNIYNQDSClqqtnpKPIKAIMNLVTGVTSLAFNPTTEILAVA 481
Cdd:cd00200   208 TGKCLGTL--RGHENGVnSVAFSPDGYLLASGSEDGTIRVWDLRTG------ECVQTLSGHTNSVTSLAWSPDGKRLASG 279


                  .
gi 1958658762 482 S 482
Cdd:cd00200   280 S 280
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 339-410 3.71e-04

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 42.72  E-value: 3.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958658762 339 VSPDGSFLL-ISGIAGFSHLLSMKTKELIGSMKINGRISASTFSSDSKRIYTSSG-NGEVYVWDVNSRKCINRF 410
Cdd:TIGR03866 132 VSPDGKIVVnTSETTNMAHWIDTATYEIVDNTLVDARPRFAEFTADGKELWVSSEiGGTVTVIDVATRKVIKKI 205
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
232-540 4.26e-31

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 125.02  E-value: 4.26e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 232 RPANAERPTTARISSVQFHPGAQVVMVSGVDHAISLFQVDgkTNPKIQSIYLEKFPIFKACFSANGeEVLATSMHSKVIY 311
Cdd:COG2319   111 LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLA--TGKLLRTLTGHSGAVTSVAFSPDG-KLLASGSDDGTVR 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 312 VYDMIAGKLIpvHQVRGlKEKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKI-NGRISASTFSSDSKRIYTS 390
Cdd:COG2319   188 LWDLATGKLL--RTLTG-HTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPDGRLLASG 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 391 SGNGEVYVWDVNSRKCInRFLDEGSLYGLSIAASKNGQYVACGSKSGVVNIYNQDSclqqtnPKPIKAIMNLVTGVTSLA 470
Cdd:COG2319   265 SADGTVRLWDLATGELL-RTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLAT------GKLLRTLTGHTGAVRSVA 337

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 471 FNPTTEILAVASRkmKEAVRLVHLPSCTVFSNFPVYKkstlSRVQTMDFSPRGGYFALGNEQGKALLYRL 540
Cdd:COG2319   338 FSPDGKTLASGSD--DGTVRLWDLATGELLRTLTGHT----GAVTSVAFSPDGRTLASGSADGTVRLWDL 401
WD40 COG2319
WD40 repeat [General function prediction only];
184-541 6.50e-30

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 121.56  E-value: 6.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 184 DWAEPGSKRKTSSDDESEEDEDDLLQRTGNFISTSTSLPRGILKMKNCRPANAERPTTARISSVQFHPGAQVVMVSGVDH 263
Cdd:COG2319    21 LAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 264 AISLFQVDGKTNPKIQSIYLEkfPIFKACFSANGEeVLATSMHSKVIYVYDMIAGKLIpvHQVRGlKEKIVKRFEVSPDG 343
Cdd:COG2319   101 TVRLWDLATGLLLRTLTGHTG--AVRSVAFSPDGK-TLASGSADGTVRLWDLATGKLL--RTLTG-HSGAVTSVAFSPDG 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 344 SFLLISGIAGFSHLLSMKTKELIGSMKI-NGRISASTFSSDSKRIYTSSGNGEVYVWDVNSRKCInRFLDEGSLYGLSIA 422
Cdd:COG2319   175 KLLASGSDDGTVRLWDLATGKLLRTLTGhTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL-RTLTGHSGSVRSVA 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 423 ASKNGQYVACGSKSGVVNIYNQDSclqqtnPKPIKAIMNLVTGVTSLAFNPTTEILAVASRKmkEAVRLVHLPSCTVFSN 502
Cdd:COG2319   254 FSPDGRLLASGSADGTVRLWDLAT------GELLRTLTGHSGGVNSVAFSPDGKLLASGSDD--GTVRLWDLATGKLLRT 325

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1958658762 503 FPVYKkstlSRVQTMDFSPRGGYFALGNEQGKALLYRLH 541
Cdd:COG2319   326 LTGHT----GAVRSVAFSPDGKTLASGSDDGTVRLWDLA 360
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 244-482 1.96e-20

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 91.63  E-value: 1.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 244 ISSVQFHPGAQVVMVSGVDHAISLFqvDGKTNPKIQSIYLEKFPIFKACFSANGEeVLATSMHSKVIYVYDMIAGKLIPV 323
Cdd:cd00200    54 VRDVAASADGTYLASGSSDKTIRLW--DLETGECVRTLTGHTSYVSSVAFSPDGR-ILSSSSRDKTIKVWDVETGKCLTT 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 324 hqVRGlKEKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKI-NGRISASTFSSDSKRIYTSSGNGEVYVWDVN 402
Cdd:cd00200   131 --LRG-HTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGhTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLS 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 403 SRKCINRFldEGSLYGL-SIAASKNGQYVACGSKSGVVNIYNQDSClqqtnpKPIKAIMNLVTGVTSLAFNPTTEILAVA 481
Cdd:cd00200   208 TGKCLGTL--RGHENGVnSVAFSPDGYLLASGSEDGTIRVWDLRTG------ECVQTLSGHTNSVTSLAWSPDGKRLASG 279


                  .
gi 1958658762 482 S 482
Cdd:cd00200   280 S 280
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 241-527 4.92e-18

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 84.69  E-value: 4.92e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 241 TARISSVQFHPGAQVVMVSGVDHAISLFQVDgkTNPKIQSIYLEKFPIFKACFSANGEEVLATSMhSKVIYVYDMIAGKL 320
Cdd:cd00200     9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLE--TGELLRTLKGHTGPVRDVAASADGTYLASGSS-DKTIRLWDLETGEC 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 321 IpvHQVRGLKEKiVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMK-INGRISASTFSSDSKRIYTSSGNGEVYVW 399
Cdd:cd00200    86 V--RTLTGHTSY-VSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRgHTDWVNSVAFSPDGTFVASSSQDGTIKLW 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 400 DVNSRKCINRFLD-EGSLYglSIAASKNGQYVACGSKSGVVNIYNQDS--CLQQTNPKPikaimnlvTGVTSLAFNPTTE 476
Cdd:cd00200   163 DLRTGKCVATLTGhTGEVN--SVAFSPDGEKLLSSSSDGTIKLWDLSTgkCLGTLRGHE--------NGVNSVAFSPDGY 232

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958658762 477 ILAVASRkmKEAVRL--VHLPSCtvfsnfpvykKSTLS----RVQTMDFSPRGGYFA 527
Cdd:cd00200   233 LLASGSE--DGTIRVwdLRTGEC----------VQTLSghtnSVTSLAWSPDGKRLA 277
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 241-443 3.00e-15

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 76.22  E-value: 3.00e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 241 TARISSVQFHPGAQVVMVSGVDHAISLFQVDgkTNPKIQSIYLEKFPIFKACFSANGeEVLATSMHSKVIYVYDMIAGKL 320
Cdd:cd00200    93 TSYVSSVAFSPDGRILSSSSRDKTIKVWDVE--TGKCLTTLRGHTDWVNSVAFSPDG-TFVASSSQDGTIKLWDLRTGKC 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 321 I---PVHqvrglkEKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKI-NGRISASTFSSDSKRIYTSSGNGEV 396
Cdd:cd00200   170 VatlTGH------TGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLASGSEDGTI 243

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958658762 397 YVWDVNSRKCInrfldeGSLYG-----LSIAASKNGQYVACGSKSGVVNIYN 443
Cdd:cd00200   244 RVWDLRTGECV------QTLSGhtnsvTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
241-403 1.43e-13

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 72.64  E-value: 1.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 241 TARISSVQFHPGAQVVMVSGVDHAISLFQVDgkTNPKIQSIYLEKFPIFKACFSANGEeVLATSMHSKVIYVYDMIAGKL 320
Cdd:COG2319   246 SGSVRSVAFSPDGRLLASGSADGTVRLWDLA--TGELLRTLTGHSGGVNSVAFSPDGK-LLASGSDDGTVRLWDLATGKL 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 321 IPVHQVRGlkeKIVKRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMK-INGRISASTFSSDSKRIYTSSGNGEVYVW 399
Cdd:COG2319   323 LRTLTGHT---GAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTgHTGAVTSVAFSPDGRTLASGSADGTVRLW 399


                  ....
gi 1958658762 400 DVNS 403
Cdd:COG2319   400 DLAT 403
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
295-446 2.84e-08

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 54.70  E-value: 2.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 295 ANGEEVLATSMHSKVIYVYDMIAGKLIPVHQVRGLKEKIVkrfeVSPDGSFLLISgiAGFSHLLS---MKTKELIGSMKI 371
Cdd:COG3391    77 ADGRRLYVANSGSGRVSVIDLATGKVVATIPVGGGPRGLA----VDPDGGRLYVA--DSGNGRVSvidTATGKVVATIPV 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 372 NGRISASTFSSDSKRIY-TSSGNGE----VYVWDVNSRKCINRfLDEGSlYGLSIAASKNGQ--YVACG------SKSGV 438
Cdd:COG3391   151 GAGPHGIAVDPDGKRLYvANSGSNTvsviVSVIDTATGKVVAT-IPVGG-GPVGVAVSPDGRrlYVANRgsntsnGGSNT 228


                  ....*...
gi 1958658762 439 VNIYNQDS 446
Cdd:COG3391   229 VSVIDLAT 236
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
252-404 2.53e-07

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 52.00  E-value: 2.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 252 GAQVVMVSGVDHAISLFqvDGKTNPKIQSIYLEKFPIFkACFSANGEEVLATSMHSKVIYVYDMIAGKL---IPV-HQVR 327
Cdd:COG3391    79 GRRLYVANSGSGRVSVI--DLATGKVVATIPVGGGPRG-LAVDPDGGRLYVADSGNGRVSVIDTATGKVvatIPVgAGPH 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 328 GLkekivkrfEVSPDGSFLLISGIAGFS-----HLLSMKTKELIGSMKINGRISASTFSSDSKRIY--------TSSGNG 394
Cdd:COG3391   156 GI--------AVDPDGKRLYVANSGSNTvsvivSVIDTATGKVVATIPVGGGPVGVAVSPDGRRLYvanrgsntSNGGSN 227

                         170
                  ....*....|
gi 1958658762 395 EVYVWDVNSR 404
Cdd:COG3391   228 TVSVIDLATL 237
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 339-410 3.71e-04

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 42.72  E-value: 3.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958658762 339 VSPDGSFLL-ISGIAGFSHLLSMKTKELIGSMKINGRISASTFSSDSKRIYTSSG-NGEVYVWDVNSRKCINRF 410
Cdd:TIGR03866 132 VSPDGKIVVnTSETTNMAHWIDTATYEIVDNTLVDARPRFAEFTADGKELWVSSEiGGTVTVIDVATRKVIKKI 205
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
234-355 1.37e-03

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 41.05  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 234 ANAERPTTARISSVQFHPGAQVVMVS--GVDHaISLFQVDGKTNPkiqsiyLEKFPIFKA---------CFSANGEEV-L 301
Cdd:COG2706   142 PNPERQEGPHAHSVVFDPDGRFLYVPdlGTDR-IYVYRLDPATGK------LPEPPEVSLppgsgprhlAFHPNGRFAyV 214

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958658762 302 ATSMHSKV-IYVYDMIAGKLIPVHQVRGLKEKIVKRF-----EVSPDGSFLLIS-----GIAGFS 355
Cdd:COG2706   215 INELDSTVsVYAYDAATGTLTLIQTVSTLPEDFTGENwaadiHISPDGRFLYVSnrghnSIAVFA 279
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 292-405 7.02e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 37.34  E-value: 7.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958658762 292 CFSANGEEVLATSMHSKV--IYVYDMIAGKLIPVHQVRGlkekIVKRFEVSPDGSFLL-ISGIAGFSHLLSMKTKEliGS 368
Cdd:COG0823    37 AWSPDGRRIAFTSDRGGGpqIYVVDADGGEPRRLTFGGG----YNASPSWSPDGKRLAfVSRSDGRFDIYVLDLDG--GA 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1958658762 369 MKI--NGRISAStFSSDSKRIYTSS---GNGEVYVWDVNSRK 405
Cdd:COG0823   111 PRRltDGPGSPS-WSPDGRRIVFSSdrgGRPDLYVVDLDGRK 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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