NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1958761263|ref|XP_038960717|]
View 

actin-related protein 2/3 complex subunit 5-like protein isoform X1 [Rattus norvegicus]

Protein Classification

actin-related protein 2/3 complex subunit 5 family protein( domain architecture ID 10520192)

actin-related protein 2/3 complex subunit 5 (ARPC5) family protein similar to ARPC5, a component of the Arp2/3 complex that mediates actin polymerization upon stimulation by nucleation-promoting factor

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
P16-Arc pfam04699
ARP2/3 complex 16 kDa subunit (p16-Arc); The Arp2/3 protein complex has been implicated in the ...
 1-99 9.15e-53

ARP2/3 complex 16 kDa subunit (p16-Arc); The Arp2/3 protein complex has been implicated in the control of actin polymerization. The human complex consists of seven subunits which include the actin related proteins Arp2 and Arp3, and five others referred to as p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc. The precise function of p16-Arc is currently unknown. Its structure consists of a single domain containing a bundle of seven alpha helices.


:

Pssm-ID: 461399  Cd Length: 146  Bit Score: 161.52  E-value: 9.15e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761263   1 MLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHE 80
Cdd:pfam04699  48 AEGALKLALDNPPYGADEQAAKDLHLQTVLEVLSSIKSSDITNIVKSLDSEQQDVLMKYLYKGMSLPSEKSGSVLLSWHE 127

                          90
                  ....*....|....*....
gi 1958761263  81 KALAVGGLGSIIRVLTARK 99
Cdd:pfam04699 128 KLVEVAGVGCIVRVLTDRR 146
 
Name Accession Description Interval E-value
P16-Arc pfam04699
ARP2/3 complex 16 kDa subunit (p16-Arc); The Arp2/3 protein complex has been implicated in the ...
 1-99 9.15e-53

ARP2/3 complex 16 kDa subunit (p16-Arc); The Arp2/3 protein complex has been implicated in the control of actin polymerization. The human complex consists of seven subunits which include the actin related proteins Arp2 and Arp3, and five others referred to as p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc. The precise function of p16-Arc is currently unknown. Its structure consists of a single domain containing a bundle of seven alpha helices.


Pssm-ID: 461399  Cd Length: 146  Bit Score: 161.52  E-value: 9.15e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761263   1 MLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHE 80
Cdd:pfam04699  48 AEGALKLALDNPPYGADEQAAKDLHLQTVLEVLSSIKSSDITNIVKSLDSEQQDVLMKYLYKGMSLPSEKSGSVLLSWHE 127

                          90
                  ....*....|....*....
gi 1958761263  81 KALAVGGLGSIIRVLTARK 99
Cdd:pfam04699 128 KLVEVAGVGCIVRVLTDRR 146
 
Name Accession Description Interval E-value
P16-Arc pfam04699
ARP2/3 complex 16 kDa subunit (p16-Arc); The Arp2/3 protein complex has been implicated in the ...
 1-99 9.15e-53

ARP2/3 complex 16 kDa subunit (p16-Arc); The Arp2/3 protein complex has been implicated in the control of actin polymerization. The human complex consists of seven subunits which include the actin related proteins Arp2 and Arp3, and five others referred to as p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc. The precise function of p16-Arc is currently unknown. Its structure consists of a single domain containing a bundle of seven alpha helices.


Pssm-ID: 461399  Cd Length: 146  Bit Score: 161.52  E-value: 9.15e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958761263   1 MLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHE 80
Cdd:pfam04699  48 AEGALKLALDNPPYGADEQAAKDLHLQTVLEVLSSIKSSDITNIVKSLDSEQQDVLMKYLYKGMSLPSEKSGSVLLSWHE 127

                          90
                  ....*....|....*....
gi 1958761263  81 KALAVGGLGSIIRVLTARK 99
Cdd:pfam04699 128 KLVEVAGVGCIVRVLTDRR 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH