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Conserved domains on  [gi|1958780249|ref|XP_038967201|]
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phosphatase and actin regulator 4 isoform X5 [Rattus norvegicus]

Protein Classification

RPEL repeat-containing protein( domain architecture ID 10499653)

RPEL repeat-containing protein such as Phactrs 1-4, a family of protein phosphatase 1 and actin regulatory proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
592-616 8.98e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.85  E-value: 8.98e-06
                           10        20
                   ....*....|....*....|....*
gi 1958780249  592 TLIRRLSQRPTAEELEQRNILQPKN 616
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 75-97 4.67e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


:

Pssm-ID: 460677  Cd Length: 24  Bit Score: 40.72  E-value: 4.67e-05
                          10        20
                  ....*....|....*....|...
gi 1958780249  75 LERKISMRKPREELVKRGVLLED 97
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPED 24
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
629-654 1.63e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 39.00  E-value: 1.63e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958780249  629 RRLTRKLSQRPTVAELLARKILRFNE 654
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 144-526 9.24e-04

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 9.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  144 TPEEDPKKRLGSTGSQPSSEAEPGPEQASKQPLLPPKRPLSSSDEGNEGQAKEVPAGSAarPVSSTSGSGIETPAATTAA 223
Cdd:PHA03247  2707 TPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAG--PPAPAPPAAPAAGPPRRLT 2784

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  224 TDMTKTLTKSFVASTPAPTPAPRTLPAAPASTNTTATHPAPAKQPPIPPPKPAQRNSNPIIAELSQAMNSGTLLSKPSPP 303
Cdd:PHA03247  2785 RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRR 2864

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  304 LPPKRGIPSTSVSSSEPAASATAKTANDQREKTVSLCLEPPLTIPPSSPSPPLPTHIPPEPPRSPLVPAKTfQMVPEVEF 383
Cdd:PHA03247  2865 RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-PPRPQPPL 2943

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  384 SPSLDrfqDISQQEDQKKEVPKKIQDQSFGESHIPSRLPPVPlhiriQQALTSPLPVTPPLEGTHRAHSLLFESSDSFSE 463
Cdd:PHA03247  2944 APTTD---PAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQP-----APSREAPASSTPPLTGHSLSRVSSWASSLALHE 3015

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958780249  464 DTG----TLGRTRSLPITIE-------MLKVPDDDEEEQICPFVEDMTSTSATPKLPPCLQEEEKESDSDSEGP 526
Cdd:PHA03247  3016 ETDpppvSLKQTLWPPDDTEdsdadslFDSDSERSDLEALDPLPPEPHDPFAHEPDPATPEAGARESPSSQFGP 3089
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
592-616 8.98e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.85  E-value: 8.98e-06
                           10        20
                   ....*....|....*....|....*
gi 1958780249  592 TLIRRLSQRPTAEELEQRNILQPKN 616
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 593-614 1.88e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 41.88  E-value: 1.88e-05
                          10        20
                  ....*....|....*....|..
gi 1958780249 593 LIRRLSQRPTAEELEQRNILQP 614
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 75-97 4.67e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 40.72  E-value: 4.67e-05
                          10        20
                  ....*....|....*....|...
gi 1958780249  75 LERKISMRKPREELVKRGVLLED 97
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPED 24
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
629-654 1.63e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 39.00  E-value: 1.63e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958780249  629 RRLTRKLSQRPTVAELLARKILRFNE 654
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
PHA03247 PHA03247
large tegument protein UL36; Provisional
 144-526 9.24e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 9.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  144 TPEEDPKKRLGSTGSQPSSEAEPGPEQASKQPLLPPKRPLSSSDEGNEGQAKEVPAGSAarPVSSTSGSGIETPAATTAA 223
Cdd:PHA03247  2707 TPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAG--PPAPAPPAAPAAGPPRRLT 2784

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  224 TDMTKTLTKSFVASTPAPTPAPRTLPAAPASTNTTATHPAPAKQPPIPPPKPAQRNSNPIIAELSQAMNSGTLLSKPSPP 303
Cdd:PHA03247  2785 RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRR 2864

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  304 LPPKRGIPSTSVSSSEPAASATAKTANDQREKTVSLCLEPPLTIPPSSPSPPLPTHIPPEPPRSPLVPAKTfQMVPEVEF 383
Cdd:PHA03247  2865 RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-PPRPQPPL 2943

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  384 SPSLDrfqDISQQEDQKKEVPKKIQDQSFGESHIPSRLPPVPlhiriQQALTSPLPVTPPLEGTHRAHSLLFESSDSFSE 463
Cdd:PHA03247  2944 APTTD---PAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQP-----APSREAPASSTPPLTGHSLSRVSSWASSLALHE 3015

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958780249  464 DTG----TLGRTRSLPITIE-------MLKVPDDDEEEQICPFVEDMTSTSATPKLPPCLQEEEKESDSDSEGP 526
Cdd:PHA03247  3016 ETDpppvSLKQTLWPPDDTEdsdadslFDSDSERSDLEALDPLPPEPHDPFAHEPDPATPEAGARESPSSQFGP 3089
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 630-653 1.50e-03

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 36.48  E-value: 1.50e-03
                          10        20
                  ....*....|....*....|....
gi 1958780249 630 RLTRKLSQRPTVAELLARKILRFN 653
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24
 
Name Accession Description Interval E-value
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
592-616 8.98e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 42.85  E-value: 8.98e-06
                           10        20
                   ....*....|....*....|....*
gi 1958780249  592 TLIRRLSQRPTAEELEQRNILQPKN 616
Cdd:smart00707   2 VLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 593-614 1.88e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 41.88  E-value: 1.88e-05
                          10        20
                  ....*....|....*....|..
gi 1958780249 593 LIRRLSQRPTAEELEQRNILQP 614
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPE 23
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 75-97 4.67e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 40.72  E-value: 4.67e-05
                          10        20
                  ....*....|....*....|...
gi 1958780249  75 LERKISMRKPREELVKRGVLLED 97
Cdd:pfam02755   2 LERKLSHRPTREELVERNILPED 24
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
629-654 1.63e-04

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 39.00  E-value: 1.63e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958780249  629 RRLTRKLSQRPTVAELLARKILRFNE 654
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26
PHA03247 PHA03247
large tegument protein UL36; Provisional
 144-526 9.24e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 9.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  144 TPEEDPKKRLGSTGSQPSSEAEPGPEQASKQPLLPPKRPLSSSDEGNEGQAKEVPAGSAarPVSSTSGSGIETPAATTAA 223
Cdd:PHA03247  2707 TPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAG--PPAPAPPAAPAAGPPRRLT 2784

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  224 TDMTKTLTKSFVASTPAPTPAPRTLPAAPASTNTTATHPAPAKQPPIPPPKPAQRNSNPIIAELSQAMNSGTLLSKPSPP 303
Cdd:PHA03247  2785 RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRR 2864

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  304 LPPKRGIPSTSVSSSEPAASATAKTANDQREKTVSLCLEPPLTIPPSSPSPPLPTHIPPEPPRSPLVPAKTfQMVPEVEF 383
Cdd:PHA03247  2865 RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-PPRPQPPL 2943

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958780249  384 SPSLDrfqDISQQEDQKKEVPKKIQDQSFGESHIPSRLPPVPlhiriQQALTSPLPVTPPLEGTHRAHSLLFESSDSFSE 463
Cdd:PHA03247  2944 APTTD---PAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQP-----APSREAPASSTPPLTGHSLSRVSSWASSLALHE 3015

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958780249  464 DTG----TLGRTRSLPITIE-------MLKVPDDDEEEQICPFVEDMTSTSATPKLPPCLQEEEKESDSDSEGP 526
Cdd:PHA03247  3016 ETDpppvSLKQTLWPPDDTEdsdadslFDSDSERSDLEALDPLPPEPHDPFAHEPDPATPEAGARESPSSQFGP 3089
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 630-653 1.50e-03

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 36.48  E-value: 1.50e-03
                          10        20
                  ....*....|....*....|....
gi 1958780249 630 RLTRKLSQRPTVAELLARKILRFN 653
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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