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Conserved domains on  [gi|1958645956|ref|XP_038969272|]
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nuclear mitotic apparatus protein 1 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.17e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 176.22  E-value: 1.17e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956    6 TRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956   86 KVMEG--SEMELAKMVMLFLYHSTMSSRNPrdWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1872-1930 1.66e-25

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 100.75  E-value: 1.66e-25
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956 1872 LLSLPGYRPTTRSSARRSQtrtSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNR 1930
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1321 1.55e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 109.38  E-value: 1.55e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  530 LQTLQEQEQAAQGLRQQVEQLssslklkeqqleeaakeqeaaRQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDA 609
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAEL---------------------RELELALLVLRLEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKateREKVVQ 689
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  690 EKVQLQEQLQALEETLKivrgSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLE 769
Cdd:TIGR02168  338 ELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  770 EAH---QAETEALRHELAGATAAQHGAE-SEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQE--- 842
Cdd:TIGR02168  414 DRRerlQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARlds 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  843 ----EQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQqVQEK---------EARAQKLLDDLSALREKMAATNKEVACLK 909
Cdd:TIGR02168  494 lerlQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  910 ALVL-----KAGEQQAAASHELKEPPRAGNQESDWEE--EQARPLGS------------TQAALKAVQREAEQM----GG 966
Cdd:TIGR02168  573 VTFLpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKfdPKLRKALSyllggvlvvddlDNALELAKKLRPGYRivtlDG 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQekaakaelemrLQNTLNEQRVEFAALQEALTHAMTEK 1046
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-----------LEKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1047 EGKDQELAKLREQeaaqiseLKALQQtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEISKL 1126
Cdd:TIGR02168  722 EELSRQISALRKD-------LARLEA------------------------------------------EVEQLEERIAQL 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1127 ERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ 1206
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1207 VARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL--QVETASSSARAAE-RSSA 1283
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSE 912

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958645956 1284 LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQ 1321
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1115-1633 4.84e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.72  E-value: 4.84e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1355 LPAKHLcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1425
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1426 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1503
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCL 1583
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1584 QTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLE 1633
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
PRK02224 super family cl32023
DNA double-strand break repair Rad50 ATPase;
243-738 1.03e-11

DNA double-strand break repair Rad50 ATPase;


The actual alignment was detected with superfamily member PRK02224:

Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 1.03e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  243 TEKDAQIAMMQQRIDHlALLNEKQAASPQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  383 EKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  463 ASLVADLQSSVSNLSQAKEELQ--------------------QASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  523 K-----KEQAQMLQ--------TLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQeaarQDHAQQLATIVEAREas 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA----EEAREEVAELNSKLA-- 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  590 vrERDAARQQLETLEkEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELH-----ACIEAAHQEQRQAQ 664
Cdd:PRK02224   583 --ELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEaefdeARIEEAREDKERAE 659

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645956  665 AHVTELEAQLkaeQQKATEREKVVQEKVQLQEQLQALEEtLKIVRGSLeEEKCRAADALKEQQRHATEMEAETR 738
Cdd:PRK02224   660 EYLEQVEEKL---DELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLR 728
MreC super family cl46468
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ...
 1613-1674 1.50e-03

rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped.


The actual alignment was detected with superfamily member COG1792:

Pssm-ID: 480808  Cd Length: 282  Bit Score: 42.95  E-value: 1.50e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958645956 1613 THYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLgRELqqagLKTKEAEQAcRHLTAQV 1674
Cdd:COG1792     68 RSLFNLREENERLKEENAELRAELQRLEELEAENARL-REL----LDLKERLDY-KFVAAEV 123
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 1735-2018 1.70e-03

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1735 TPCSVASKLPRTQPDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGQA--PLETSLDSLGDAFPDSGRKTRSARRR 1812
Cdd:PHA03307   179 PEETARAPSSPPAEPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1813 TTQIINITMTKKLELEEPDsaNSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRP-----TTRSSAR 1887
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSES 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1888 RSQTRTSSGAPHGRNsfymGTCQDEPeqvdDWNRIAELQQRNRvcpphlktcypleSRPALSLATITdeemktgDPRETL 1967
Cdd:PHA03307   336 SRGAAVSPGPSPSRS----PSPSRPP----PPADPSSPRKRPR-------------PSRAPSSPAAS-------AGRPTR 387

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645956 1968 RRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATscfPRPMTP 2018
Cdd:PHA03307   388 RRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR---YPLLTP 435
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.17e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 176.22  E-value: 1.17e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956    6 TRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956   86 KVMEG--SEMELAKMVMLFLYHSTMSSRNPrdWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1872-1930 1.66e-25

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 100.75  E-value: 1.66e-25
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956 1872 LLSLPGYRPTTRSSARRSQtrtSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNR 1930
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1321 1.55e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 109.38  E-value: 1.55e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  530 LQTLQEQEQAAQGLRQQVEQLssslklkeqqleeaakeqeaaRQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDA 609
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAEL---------------------RELELALLVLRLEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKateREKVVQ 689
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  690 EKVQLQEQLQALEETLKivrgSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLE 769
Cdd:TIGR02168  338 ELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  770 EAH---QAETEALRHELAGATAAQHGAE-SEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQE--- 842
Cdd:TIGR02168  414 DRRerlQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARlds 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  843 ----EQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQqVQEK---------EARAQKLLDDLSALREKMAATNKEVACLK 909
Cdd:TIGR02168  494 lerlQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  910 ALVL-----KAGEQQAAASHELKEPPRAGNQESDWEE--EQARPLGS------------TQAALKAVQREAEQM----GG 966
Cdd:TIGR02168  573 VTFLpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKfdPKLRKALSyllggvlvvddlDNALELAKKLRPGYRivtlDG 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQekaakaelemrLQNTLNEQRVEFAALQEALTHAMTEK 1046
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-----------LEKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1047 EGKDQELAKLREQeaaqiseLKALQQtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEISKL 1126
Cdd:TIGR02168  722 EELSRQISALRKD-------LARLEA------------------------------------------EVEQLEERIAQL 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1127 ERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ 1206
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1207 VARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL--QVETASSSARAAE-RSSA 1283
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSE 912

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958645956 1284 LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQ 1321
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1115-1633 4.84e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.72  E-value: 4.84e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1355 LPAKHLcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1425
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1426 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1503
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCL 1583
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1584 QTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLE 1633
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 589-1345 1.20e-21

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 103.68  E-value: 1.20e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  589 SVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQR-----EKAELSQKIGELHACIEAAHQEQRQA 663
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKaeeakKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  664 QAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEetlkiVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQ 743
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE-----VRKAEELRKAEDARKAEAARKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  744 REQEQKELEQEKAERKGLEARLQQLE---EAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEAR 820
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEErnnEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKK 1302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  821 ygamfqeqlmalKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAA 900
Cdd:PTZ00121  1303 ------------KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  901 TNKEVACLKALVLKAGEQQAAASHELKEPPragnQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQG 980
Cdd:PTZ00121  1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKA----EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  981 QQQEVRGQQEREVARLTQERGQAQAdlAQEKAAKAElEMRLQNTLNEQRVEFAALQEALTHAMTEKEgKDQELAKLREQE 1060
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKK--ADEAKKKAE-EAKKADEAKKKAEEAKKKADEAKKAAEAKK-KADEAKKAEEAK 1522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1061 AAQisELKALQQTLEELKKKEKEHPTggaRGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGL 1140
Cdd:PTZ00121  1523 KAD--EAKKAEEAKKADEAKKAEEKK---KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1141 THSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRaKAQDHSKAEEEWK---AQVARGQQEAERK 1217
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK-KAEELKKAEEENKikaAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1218 SSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLE-----ERLRLLQVETASssaRAAERSSALREEVQslR 1292
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEelkkaEEENKIKAEEAK---KEAEEDKKKAEEAK--K 1751

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645956 1293 EEVEKQRVvsenlRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHT 1345
Cdd:PTZ00121  1752 DEEEKKKI-----AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 412-971 2.56e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 2.56e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  412 QLDTLKQEAAKLATDntELQARVETLECERGKQEAQLLAErghfEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQG 491
Cdd:COG1196    221 ELKELEAELLLLKLR--ELEAELEELEAELEELEAELEEL----EAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  492 AQL----------TAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:COG1196    295 AELarleqdiarlEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  562 EEAAKEQEAARQDHAQQLATIVEAREAsVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAE 641
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQ-LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  642 LSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAAD 721
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  722 ALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLqQLEEAHQAETEALRHELAGATAAQHGAESEREQLL 801
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL-PLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  802 REVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKE 881
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  882 ARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGstqAALKAVQREA 961
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP---PDLEELEREL 769

                          570
                   ....*....|
gi 1958645956  962 EQMGGELERL 971
Cdd:COG1196    770 ERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1664 4.67e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 91.74  E-value: 4.67e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  959 REAEQMGGELERLRAALMQSQGQQQEVRGQQER----EVARLTQERGQAQADLAQEKAAKAELEMRLQNTlneQRVEFAA 1034
Cdd:PTZ00121  1088 RADEATEEAFGKAEEAKKTETGKAEEARKAEEAkkkaEDARKAEEARKAEDARKAEEARKAEDAKRVEIA---RKAEDAR 1164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1035 LQEALTHAmteKEGKDQELAKlREQEAAQISELKALQQTLEELKKKEKEHPTggaRGEDASGDGPGSQLHTPGKTE-APG 1113
Cdd:PTZ00121  1165 KAEEARKA---EDAKKAEAAR-KAEEVRKAEELRKAEDARKAEAARKAEEER---KAEEARKAEDAKKAEAVKKAEeAKK 1237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1114 PEVEALRAEisKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARElghnQAASASAQRELQALRAKA 1193
Cdd:PTZ00121  1238 DAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKA 1311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1194 QDHSKAEE--------EWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvaESEKSQKLEERLRL 1265
Cdd:PTZ00121  1312 EEAKKADEakkkaeeaKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK----EEAKKKADAAKKKA 1387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1266 LQVETASSSARAAERSSALREEVQslREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHT 1345
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELK--KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1346 STQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAA-GGLQAELMRAQRELGELGSLRQkiVEQERAAQQLR-AE 1423
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAeAKKKADEAKKAEEAKKADEAKK--AEEAKKADEAKkAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1424 KASYAEQLSM---LKKAHGLL-AEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAETHLAEMRQEAqstsrel 1499
Cdd:PTZ00121  1544 EKKKADELKKaeeLKKAEEKKkAEEAKKAEEDKNMALRKAE-EAKKAEEARIEEVMKLYEEEKKMKAEEAKKA------- 1615

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1500 evmtakyESAKVKVlEERQRFQEERQKltaqVEQLEVFHREQTKQVEELNKKltESEQASRVQQQKLKAFQAqggesqqe 1579
Cdd:PTZ00121  1616 -------EEAKIKA-EELKKAEEEKKK----VEQLKKKEAEEKKKAEELKKA--EEENKIKAAEEAKKAEED-------- 1673

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1580 vqclQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQlqdlEQLQKDNKELRSETERLGRELQQAGLK 1659
Cdd:PTZ00121  1674 ----KKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA----EELKKAEEENKIKAEEAKKEAEEDKKK 1745


                   ....*
gi 1958645956 1660 TKEAE 1664
Cdd:PTZ00121  1746 AEEAK 1750
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1003-1682 1.65e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.65e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1003 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALTHA-----MTEKEGKDQELAKLREQEAAQISELKALQQTL 1074
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1075 EELKKKEKEHPTGGARGEDASGDGPGsqlhtpgkteapgpEVEALRAEISKLERQWQQQQQQVEGLTHSLEseracraEQ 1154
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK--------------ELYALANEISRLEQQKQILRERLANLERQLE-------EL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1155 DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNrq 1234
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-- 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1235 vlekegeskelKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAE 1314
Cdd:TIGR02168  400 -----------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1315 RAEESGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREEIEQSKQAAGG--L 1389
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGgrL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1390 QAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM----------- 1433
Cdd:TIGR02168  548 QAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1434 ---LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKyVQELAAVRTDAETHLAEMRQE 1491
Cdd:TIGR02168  628 vddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEK-IEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1492 AQSTSRELEVMTAKYESAKVKVLEER---QRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKA 1568
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1569 FQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQD-----------LEQLQK 1637
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEElsedieslaaeIEELEE 866

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1958645956 1638 DNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQAS 1682
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
243-738 1.03e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 1.03e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  243 TEKDAQIAMMQQRIDHlALLNEKQAASPQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  383 EKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  463 ASLVADLQSSVSNLSQAKEELQ--------------------QASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  523 K-----KEQAQMLQ--------TLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQeaarQDHAQQLATIVEAREas 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA----EEAREEVAELNSKLA-- 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  590 vrERDAARQQLETLEkEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELH-----ACIEAAHQEQRQAQ 664
Cdd:PRK02224   583 --ELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEaefdeARIEEAREDKERAE 659

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645956  665 AHVTELEAQLkaeQQKATEREKVVQEKVQLQEQLQALEEtLKIVRGSLeEEKCRAADALKEQQRHATEMEAETR 738
Cdd:PRK02224   660 EYLEQVEEKL---DELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLR 728
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 304-879 4.75e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 4.75e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  304 KNQMDRKISQLSeengDLSFKVREFANHLQQLQGAFNDLIEEhskasqewAEKQAHL-ESELSTALQDKKCLEEKS---- 378
Cdd:pfam15921  309 RNQNSMYMRQLS----DLESTVSQLRSELREAKRMYEDKIEE--------LEKQLVLaNSELTEARTERDQFSQESgnld 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  379 EILQEKISQLEDRAAQLQGSPAPEK---GEVLGDALQLDTLKQEAAKLATDNTELQARVETLECE-RGKQEAQLLAERGH 454
Cdd:pfam15921  377 DQLQKLLADLHKREKELSLEKEQNKrlwDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGK 456

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  455 fEEEKRQLASLVADLQSSVSNLSQAKEELqqasqaqgaqltaqlaslTALNATLQQQDQELTSLKeqakkeqaqmlQTLQ 534
Cdd:pfam15921  457 -NESLEKVSSLTAQLESTKEMLRKVVEEL------------------TAKKMTLESSERTVSDLT-----------ASLQ 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  535 EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeaarQDHAQQLATiveareasvrERDAARQQLetleKEKDAKLESL 614
Cdd:pfam15921  507 EKERAIEATNAEITKLRSRVDLKLQELQHLKNE-----GDHLRNVQT----------ECEALKLQM----AEKDKVIEIL 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  615 QQQLQASNEARDTAQTSVTQAQREKAELSQKIG-------ELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKV 687
Cdd:pfam15921  568 RQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINdrrlelqEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  688 VQEKVQLQEQLQALEETLKIVRGSLEEEkcraADALKEQQRHAT-EMEAETRHLmeqreqeqkeleqeKAERKGLEARLQ 766
Cdd:pfam15921  648 VKDIKQERDQLLNEVKTSRNELNSLSED----YEVLKRNFRNKSeEMETTTNKL--------------KMQLKSAQSELE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  767 QLEEAHQAETEALRHELAGATAAQHGAESEREQlLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKE 846
Cdd:pfam15921  710 QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ-IDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1958645956  847 AGEIHG-EGQTGQQQSQLAQLHACLAKALQQVQE 879
Cdd:pfam15921  789 AGELEVlRSQERRLKEKVANMEVALDKASLQFAE 822
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1213-1565 4.42e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 61.68  E-value: 4.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1213 EAERKSSLISSLEEEVSILNRQVLEKeGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLR 1292
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEK-FEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAME 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1293 EEVEKQRVVSENLRQELasQAERAEESGQELKAWQEkffqkeqaLSALQLEHTSTQALVSELLPAkhlcqqlqaeqaAAE 1372
Cdd:pfam17380  346 RERELERIRQEERKREL--ERIRQEEIAMEISRMRE--------LERLQMERQQKNERVRQELEA------------ARK 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1373 KRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSML-------KKAHGLLAEEN 1445
Cdd:pfam17380  404 VKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLrqqeeerKRKKLELEKEK 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1446 RGLGERANLGRQFLEVELDQAREKYVQElaavRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQ 1525
Cdd:pfam17380  484 RDRKRAEEQRRKILEKELEERKQAMIEE----ERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1958645956 1526 KLTAQVEQLEVFHREQ--TKQVEELNKKLTESEQASRVQQQK 1565
Cdd:pfam17380  560 KATEERSRLEAMERERemMRQIVESEKARAEYEATTPITTIK 601
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 354-703 3.16e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 59.20  E-value: 3.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  354 AEKQAHLESelstALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGevLGDALQLD----TLKQEAAKLATDNTE 429
Cdd:COG3096    278 NERRELSER----ALELRRELFGARRQLAEEQYRLVEMARELEELSARESD--LEQDYQAAsdhlNLVQTALRQQEKIER 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  430 LQARVETLE----------CERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLS----------QAKEELQQASQA 489
Cdd:COG3096    352 YQEDLEELTerleeqeevvEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQtraiqyqqavQALEKARALCGL 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  490 QGAQLTAQLASLTALNATLQQQDQELTSLKEQ------AKKEQAQMLQTLQ------EQEQAAQGLRQQVEQLSSsLKLK 557
Cdd:COG3096    432 PDLTPENAEDYLAAFRAKEQQATEEVLELEQKlsvadaARRQFEKAYELVCkiagevERSQAWQTARELLRRYRS-QQAL 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  558 EQQLEEAAKEQEAARQDHAQQLATIVEAREASVR--ERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQA 635
Cdd:COG3096    511 AQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRigQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQL 590

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956  636 QREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEE 703
Cdd:COG3096    591 RARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALES 658
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 214-483 9.73e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 9.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  214 MRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRidhlalLNEKQAASPQEpseLEELRGKNESLTVRLHET 293
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ------LEQEEEKLKER---LEELEEDLSSLEQEIENV 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  294 LKQCQNLKTEKNQMDRKISQLSEENGDLsfKVREFANHLQQLQGAFNDLIEEHSkasqEWAEKQAHLESELSTALQDKKC 373
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVS----RIEARLREIEQKLNRLTLEKEY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  374 LEEKSEILQEKISQLEDRAAQLQGspapekgevlgdalQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERG 453
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEK--------------EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270
                   ....*....|....*....|....*....|
gi 1958645956  454 HFEEEKRQLASLVADLQSSVSNLSQAKEEL 483
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKL 926
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 252-774 6.13e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 51.71  E-value: 6.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  252 MQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS----QLSEENGDLSFKVRE 327
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  328 FANHLQQLQGafndlieEHSKASQEWAEKQAHLESELST--ALQ-DKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKG 404
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAArqKLQlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  405 EVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQllaeRGHFEEEKRQLASLVADLQSSVSNLSQAKEELQ 484
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  485 QASQAQGAQLTAQLASL---TALNATLQQQDQELTS----LKEQAKKEQAQM--------------------LQTLQEQE 537
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAqiseLQEDLESERAARnkaekqrrdlgeelealkteLEDTLDTT 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  538 QAAQGLRQQVEQLSSSLKLK-EQQLEEAAKEQEAARQDHAQQLATIVEAREASVRER---DAARQQLETLEKEKDAKLES 613
Cdd:pfam01576  316 AAQQELRSKREQEVTELKKAlEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKanlEKAKQALESENAELQAELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  614 LQQQLQASNEARDTA-------QTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREK 686
Cdd:pfam01576  396 LQQAKQDSEHKRKKLegqlqelQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  687 VVQE----KVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLE 762
Cdd:pfam01576  476 LLQEetrqKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELE 555

                          570
                   ....*....|..
gi 1958645956  763 ARLQQLEEAHQA 774
Cdd:pfam01576  556 ALTQQLEEKAAA 567
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 504-619 4.43e-04

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 44.11  E-value: 4.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  504 LNATLQQQDQELTSLKEQAKKEQAQmLQTLQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEqeaarQDHAQQLATIV 583
Cdd:NF038305    99 LNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLP-----EEQKEQLQQFK 171

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1958645956  584 EAREASVRERDAARQQLET--LEKEKDAKLESLQQQLQ 619
Cdd:NF038305   172 SNPQALDKFLAQQLTQIRTqaEEAEKQARLEALKSSLR 209
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 341-648 1.09e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  341 DLIEEHSKASQEWAEKQAHLESELST--ALQDKKCLEEKSEIL-QEKISQLEDRA---AQLQgSPAPEKGEVLGDAlQLD 414
Cdd:NF012221  1532 DNVVATSESSQQADAVSKHAKQDDAAqnALADKERAEADRQRLeQEKQQQLAAISgsqSQLE-STDQNALETNGQA-QRD 1609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  415 TLKQEAAKLATDNTELQARVETLEcergkQEAQLLAERGhfEEEKRQLA-SLVADLQSSVSNlsqakeelqqasqaqgaq 493
Cdd:NF012221  1610 AILEESRAVTKELTTLAQGLDALD-----SQATYAGESG--DQWRNPFAgGLLDRVQEQLDD------------------ 1664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  494 ltAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQveqlssslklkeqqleeaakeqeaarq 573
Cdd:NF012221  1665 --AKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDA--------------------------- 1715

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956  574 dhaqqlativeAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARdTAQTSVTQAQREKAELSQKIGE 648
Cdd:NF012221  1716 -----------KADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
MreC COG1792
Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome ...
 1613-1674 1.50e-03

Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 441397  Cd Length: 282  Bit Score: 42.95  E-value: 1.50e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958645956 1613 THYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLgRELqqagLKTKEAEQAcRHLTAQV 1674
Cdd:COG1792     68 RSLFNLREENERLKEENAELRAELQRLEELEAENARL-REL----LDLKERLDY-KFVAAEV 123
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1735-2018 1.70e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1735 TPCSVASKLPRTQPDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGQA--PLETSLDSLGDAFPDSGRKTRSARRR 1812
Cdd:PHA03307   179 PEETARAPSSPPAEPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1813 TTQIINITMTKKLELEEPDsaNSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRP-----TTRSSAR 1887
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSES 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1888 RSQTRTSSGAPHGRNsfymGTCQDEPeqvdDWNRIAELQQRNRvcpphlktcypleSRPALSLATITdeemktgDPRETL 1967
Cdd:PHA03307   336 SRGAAVSPGPSPSRS----PSPSRPP----PPADPSSPRKRPR-------------PSRAPSSPAAS-------AGRPTR 387

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645956 1968 RRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATscfPRPMTP 2018
Cdd:PHA03307   388 RRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR---YPLLTP 435
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1510-1655 1.87e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.70  E-value: 1.87e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  1510 KVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQK----LKAFQAQGGESQQEVQCLQT 1585
Cdd:smart00787  146 KEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCdpteLDRAKEKLKKLLQEIMIKVK 225

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645956  1586 QLSELQAQLSQKEQAAEhyklqmekakthydAKKQQNQELREQLQDLEQLQKDNKEL-RSETERLGRELQQ 1655
Cdd:smart00787  226 KLEELEEELQELESKIE--------------DLTNKKSELNTEIAEAEKKLEQCRGFtFKEIEKLKEQLKL 282
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 1507-1661 9.58e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 40.36  E-value: 9.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1507 ESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTE------SEQASRVQQqKLKAFQAQGGESQQEV 1580
Cdd:NF033928   108 ELSELPPIPLSSDDKEIVKELKEILEDLKNDIKDYQQKADDVKKELDDfendlrEELLPQLKL-KKKLYDDNLGSDSIEE 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1581 qcLQTQLSELQAQLSQKEQAAEHYKL----------------------QMEKAKTHYDAKKQQNQELREQLQDLEQLQKD 1638
Cdd:NF033928   187 --LREKIDQLEKEIEQLNKEYDDYVKlsftglaggpiglaitggifgsKAEKIRKEKNALIQEIDELQEQLKKKNALLGS 264

                          170       180
                   ....*....|....*....|...
gi 1958645956 1639 NKELRSETERLGRELQQAGLKTK 1661
Cdd:NF033928   265 LERLQTSLDDILTRMEDALPALK 287
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.17e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 176.22  E-value: 1.17e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956    6 TRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956   86 KVMEG--SEMELAKMVMLFLYHSTMSSRNPrdWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1872-1930 1.66e-25

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 100.75  E-value: 1.66e-25
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956 1872 LLSLPGYRPTTRSSARRSQtrtSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNR 1930
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1321 1.55e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 109.38  E-value: 1.55e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  530 LQTLQEQEQAAQGLRQQVEQLssslklkeqqleeaakeqeaaRQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDA 609
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAEL---------------------RELELALLVLRLEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKateREKVVQ 689
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  690 EKVQLQEQLQALEETLKivrgSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLE 769
Cdd:TIGR02168  338 ELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  770 EAH---QAETEALRHELAGATAAQHGAE-SEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQE--- 842
Cdd:TIGR02168  414 DRRerlQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARlds 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  843 ----EQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQqVQEK---------EARAQKLLDDLSALREKMAATNKEVACLK 909
Cdd:TIGR02168  494 lerlQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  910 ALVL-----KAGEQQAAASHELKEPPRAGNQESDWEE--EQARPLGS------------TQAALKAVQREAEQM----GG 966
Cdd:TIGR02168  573 VTFLpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKfdPKLRKALSyllggvlvvddlDNALELAKKLRPGYRivtlDG 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQekaakaelemrLQNTLNEQRVEFAALQEALTHAMTEK 1046
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-----------LEKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1047 EGKDQELAKLREQeaaqiseLKALQQtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEISKL 1126
Cdd:TIGR02168  722 EELSRQISALRKD-------LARLEA------------------------------------------EVEQLEERIAQL 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1127 ERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ 1206
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1207 VARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL--QVETASSSARAAE-RSSA 1283
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSE 912

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958645956 1284 LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQ 1321
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1115-1633 4.84e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 107.72  E-value: 4.84e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1355 LPAKHLcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1425
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1426 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1503
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCL 1583
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1584 QTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLE 1633
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 300-1070 5.96e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.45  E-value: 5.96e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  300 LKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfndlIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSE 379
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEK----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  380 ILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEK 459
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  460 RQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQA 539
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  540 AQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDH---AQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQ 616
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLegfSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGG 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  617 QLQA----SNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQL---KAEQQKATE----RE 685
Cdd:TIGR02168  546 RLQAvvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvkfDPKLRKALSyllgGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  686 KVVQEKVQLQEQLQALEETLKIVrgSLEEEKCRA------ADALKEQQRhaTEMEAETRHLMEQREQEQKELEQEKAERK 759
Cdd:TIGR02168  626 LVVDDLDNALELAKKLRPGYRIV--TLDGDLVRPggvitgGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALA 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  760 GLEARLQQLEEahqaETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKI 839
Cdd:TIGR02168  702 ELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  840 GQEEQKEAGEihgEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQ 919
Cdd:TIGR02168  778 AEAEAEIEEL---EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  920 AAASHELkeppragnqesdweEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVrgqqEREVARLTQE 999
Cdd:TIGR02168  855 ESLAAEI--------------EELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL----ESKRSELRRE 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645956 1000 RGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEaltHAMTEKEGKDQELAKLREQEAAQISELKAL 1070
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---EAEALENKIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 589-1345 1.20e-21

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 103.68  E-value: 1.20e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  589 SVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQR-----EKAELSQKIGELHACIEAAHQEQRQA 663
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKaeeakKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  664 QAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEetlkiVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQ 743
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE-----VRKAEELRKAEDARKAEAARKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  744 REQEQKELEQEKAERKGLEARLQQLE---EAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEAR 820
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEErnnEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKK 1302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  821 ygamfqeqlmalKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAA 900
Cdd:PTZ00121  1303 ------------KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  901 TNKEVACLKALVLKAGEQQAAASHELKEPPragnQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQG 980
Cdd:PTZ00121  1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKA----EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  981 QQQEVRGQQEREVARLTQERGQAQAdlAQEKAAKAElEMRLQNTLNEQRVEFAALQEALTHAMTEKEgKDQELAKLREQE 1060
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKK--ADEAKKKAE-EAKKADEAKKKAEEAKKKADEAKKAAEAKK-KADEAKKAEEAK 1522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1061 AAQisELKALQQTLEELKKKEKEHPTggaRGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGL 1140
Cdd:PTZ00121  1523 KAD--EAKKAEEAKKADEAKKAEEKK---KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1141 THSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRaKAQDHSKAEEEWK---AQVARGQQEAERK 1217
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK-KAEELKKAEEENKikaAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1218 SSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLE-----ERLRLLQVETASssaRAAERSSALREEVQslR 1292
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEelkkaEEENKIKAEEAK---KEAEEDKKKAEEAK--K 1751

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645956 1293 EEVEKQRVvsenlRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHT 1345
Cdd:PTZ00121  1752 DEEEKKKI-----AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 412-971 2.56e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 2.56e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  412 QLDTLKQEAAKLATDntELQARVETLECERGKQEAQLLAErghfEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQG 491
Cdd:COG1196    221 ELKELEAELLLLKLR--ELEAELEELEAELEELEAELEEL----EAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  492 AQL----------TAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:COG1196    295 AELarleqdiarlEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  562 EEAAKEQEAARQDHAQQLATIVEAREAsVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAE 641
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQ-LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  642 LSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAAD 721
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  722 ALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLqQLEEAHQAETEALRHELAGATAAQHGAESEREQLL 801
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL-PLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  802 REVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKE 881
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  882 ARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGstqAALKAVQREA 961
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP---PDLEELEREL 769

                          570
                   ....*....|
gi 1958645956  962 EQMGGELERL 971
Cdd:COG1196    770 ERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 330-905 2.85e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 2.85e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  330 NHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGD 409
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  410 ALQLDTLKQEAAKLATDNTELQARVETLEcergKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQA 489
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELE----EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  490 QGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQE 569
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  570 AARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQ---------ASNEARDTAQTSVTQAQREKA 640
Cdd:COG1196    471 EAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglagavavlIGVEAAYEAALEAALAAALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  641 ELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAA 720
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  721 DALKEQQRHAT--EMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESERE 798
Cdd:COG1196    631 RLEAALRRAVTlaGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  799 QLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEhgkigqEEQKEAGEIHGEGQTGQQQSQLAQLHACLAK------ 872
Cdd:COG1196    711 EAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL------LEEEALEELPEPPDLEELERELERLEREIEAlgpvnl 784

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1958645956  873 -ALQQVQEKEARAQKL---LDDLSA----LREKMAATNKEV 905
Cdd:COG1196    785 lAIEEYEELEERYDFLseqREDLEEaretLEEAIEEIDRET 825
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 207-945 7.65e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 7.65e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  207 LQTPQFQMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRI-DHLALLNEKQAASPQEPSELEELRGKNES 285
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyALANEISRLEQQKQILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  286 LTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQAHLES 362
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  363 ELSTALQDKKCLEEKSEILQEKISQLEDRaaqlqgspaPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERG 442
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  443 KQEAQLLAERGHFEEEKRQLASLVaDLQSSVSNLSQAKEELQQASQaqgaqltaQLASLTALNATLQQQDQELTSLKEQA 522
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLE-RLQENLEGFSEGVKALLKNQS--------GLSGILGVLSELISVDEGYEAAIEAA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  523 KKEQAQML--QTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQL 600
Cdd:TIGR02168  543 LGGRLQAVvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  601 ETLekekdAKLESLQQQLQASNEARD------------TAQTSVTQAQREKA----ELSQKIGELHACIEAAHQEQRQAQ 664
Cdd:TIGR02168  623 GGV-----LVVDDLDNALELAKKLRPgyrivtldgdlvRPGGVITGGSAKTNssilERRREIEELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  665 AHVTELEAQLkaeQQKATEREKVVQEKVQLQEQLQALEETLKIvrgsLEEEKCRAADALKEQQRHATEMEAETRHLMEQR 744
Cdd:TIGR02168  698 KALAELRKEL---EELEEELEQLRKELEELSRQISALRKDLAR----LEAEVEQLEERIAQLSKELTELEAEIEELEERL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  745 EQEQKELEQEKAERKGLEARLQQLEEAHQAETE---ALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARy 821
Cdd:TIGR02168  771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE- 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  822 gamFQEQLMALKGEHGKIGQEEQKEAGEI-HGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAA 900
Cdd:TIGR02168  850 ---LSEDIESLAAEIEELEELIEELESELeALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645956  901 TNKEVACLKALVLK-----AGEQQAAASHELKEPPRAGNQESDWEEEQAR 945
Cdd:TIGR02168  927 LELRLEGLEVRIDNlqerlSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 591-1419 1.20e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.66  E-value: 1.20e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  591 RERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTEL 670
Cdd:TIGR02168  207 RQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  671 EAQLkaeQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRaadaLKEQQRHATEMEAETRHLMEQREQEQKE 750
Cdd:TIGR02168  287 QKEL---YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK----LDELAEELAELEEKLEELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  751 LEQEKAERKGLEARLQQLEEAHqaetEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQlm 830
Cdd:TIGR02168  360 LEELEAELEELESRLEELEEQL----ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA-- 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  831 ALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKA 910
Cdd:TIGR02168  434 ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  911 LVLKAGEQQAAASHELkeppragNQESDWEeeqarplgstqAALKAVQREaeqmggeleRLRAALMQSQgqqqevrgqqe 990
Cdd:TIGR02168  514 NQSGLSGILGVLSELI-------SVDEGYE-----------AAIEAALGG---------RLQAVVVENL----------- 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  991 rEVARLTQErgqAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKAL 1070
Cdd:TIGR02168  556 -NAAKKAIA---FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1071 QQTLEELKKKEKEHPTGGARGEDASGDGPGSqlhtpGKTEAPGPEVEALRAEISKLERQWQQQQQQVeglthsleserac 1150
Cdd:TIGR02168  632 DNALELAKKLRPGYRIVTLDGDLVRPGGVIT-----GGSAKTNSSILERRREIEELEEKIEELEEKI------------- 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1151 rAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSI 1230
Cdd:TIGR02168  694 -AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1231 LNRQVLEKEGESKELKRLV-------VAESEKSQKLEERLRLLQVETASSSARAAE---RSSALREEVQSLREEVEKQRV 1300
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAQIeqlkeelKALREALDELRAELTLLNEEAANLRERLESlerRIAATERRLEDLEEQIEELSE 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1301 VSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIE 1380
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1958645956 1381 QSKQAAGGLQAELM-RAQRELGELGSLRQKIVEQERAAQQ 1419
Cdd:TIGR02168  933 GLEVRIDNLQERLSeEYSLTLEEAEALENKIEDDEEEARR 972
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-884 1.89e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.89  E-value: 1.89e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  213 QMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHL-----ALLNEKQAASPQE---PSELEELRGKNE 284
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkelyALANEISRLEQQKqilRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  285 SLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQAHLE 361
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  362 SELSTALQDKKCLEEKSEILQEKISQLEDRaaqlqgspaPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECER 441
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  442 GKQEAQLLAERGHFEEEKRQLASLVADLQS------SVSNLSQAKEELQQASQAQGAQLTA----QLASLTALNATLQQ- 510
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENlegfseGVKALLKNQSGLSGILGVLSELISVdegyEAAIEAALGGRLQAv 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  511 -------------------------------QDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEq 559
Cdd:TIGR02168  551 vvenlnaakkaiaflkqnelgrvtflpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD- 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  560 qlEEAAKEQEAARQDHAQQLATI--------------VEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEAR 625
Cdd:TIGR02168  630 --DLDNALELAKKLRPGYRIVTLdgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  626 DTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREkvvQEKVQLQEQLQALEEtl 705
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE---ERLEEAEEELAEAEA-- 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  706 kiVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEahqaETEALRHELAG 785
Cdd:TIGR02168  783 --EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE----QIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  786 ATAAQHGAESEREQLLREVESWQKRVEARqqeearygamfQEQLMALKGEHGKIGQEEQKEAGEIHG-EGQTGQQQSQLA 864
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASL-----------EEALALLRSELEELSEELRELESKRSElRRELEELREKLA 925

                          730       740
                   ....*....|....*....|
gi 1958645956  865 QLHACLAKALQQVQEKEARA 884
Cdd:TIGR02168  926 QLELRLEGLEVRIDNLQERL 945
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 274-823 3.01e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.39  E-value: 3.01e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  274 SELEELRGknESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEW 353
Cdd:COG1196    220 EELKELEA--ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  354 AEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGspapEKGEVLGDALQLDTLKQEAAKLATDNTELQAR 433
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE----LEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  434 VETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQ 513
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  514 ELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATI----------V 583
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavavligvE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  584 EAREASVRERDAARQQLETLEKEKDAKleSLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQA 663
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDDEVAA--AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  664 QAHVTELEAQLKAEQQKAT-------------EREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHA 730
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAArleaalrravtlaGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  731 TEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAqhgAESEREQLLREVESWQKR 810
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE---EALEELPEPPDLEELERE 768

                          570
                   ....*....|...
gi 1958645956  811 VEARQQEEARYGA 823
Cdd:COG1196    769 LERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 761-1558 5.53e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.35  E-value: 5.53e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  761 LEARLQQLE-EAHQAE-----TEALRH-ELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYgamfQEQLMALK 833
Cdd:TIGR02168  198 LERQLKSLErQAEKAErykelKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAELQEL----EEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  834 GEHGKIGQEEQKEAGEIHG--------EGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEV 905
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYAlaneisrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  906 ACLKALVLKAGEQQAAAShelkeppragNQESDWEEEqarpLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEV 985
Cdd:TIGR02168  354 ESLEAELEELEAELEELE----------SRLEELEEQ----LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  986 RGQQEREVARLT-QERGQAQADLAQEKAAKAELEMRL---QNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEA 1061
Cdd:TIGR02168  420 QQEIEELLKKLEeAELKELQAELEELEEELEELQEELerlEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1062 AQISELKALQQTLEELKKKEKEHPTGGARGEDASGD--------GPGSQLHTPGKTEAPGPEVEALR------------- 1120
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYeaaieaalGGRLQAVVVENLNAAKKAIAFLKqnelgrvtflpld 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1121 ----AEISKLERQWQQQQQQVEGLTHSLESeraCRAEQDKALETLQGQL---------EEKARELGHNQA---------- 1177
Cdd:TIGR02168  580 sikgTEIQGNDREILKNIEGFLGVAKDLVK---FDPKLRKALSYLLGGVlvvddldnaLELAKKLRPGYRivtldgdlvr 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1178 -------ASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVV 1250
Cdd:TIGR02168  657 pggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1251 AESEKSQKLEERLRLLQVEtasssaraaerSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKF 1330
Cdd:TIGR02168  737 RLEAEVEQLEERIAQLSKE-----------LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1331 FQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKqaagglqaelmraqrelGELGSLRQKI 1410
Cdd:TIGR02168  806 DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA-----------------AEIEELEELI 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1411 VEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAETHLAEMRQ 1490
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE-ELREKLAQLELRLEGLEVRIDNLQERLSE 947

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956 1491 EAQstsRELEVMTAKYESAKVKVLEERQRFQEERQKLTA----------QVEQLEVFHREQTKQVEELNKKLTESEQA 1558
Cdd:TIGR02168  948 EYS---LTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 934-1535 1.11e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.46  E-value: 1.11e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  934 NQESDWEEEQARpLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAA 1013
Cdd:COG1196    236 ELEAELEELEAE-LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1014 KAELEmRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHptggARged 1093
Cdd:COG1196    315 EERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL----AE--- 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1094 asgdgpgsqlhtpgkteapgpEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELG 1173
Cdd:COG1196    387 ---------------------ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1174 HNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEevsiLNRQVLEKEGESKELKRLVVAES 1253
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE----AEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1254 EKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQK 1333
Cdd:COG1196    522 LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1334 EQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQ 1413
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1414 ERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAET---------H 1484
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEaleelpeppD 761

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956 1485 LAEMRQEAQSTSRELEV-----MTAkyesakvkvLEERQRFQEERQKLTAQVEQLE 1535
Cdd:COG1196    762 LEELERELERLEREIEAlgpvnLLA---------IEEYEELEERYDFLSEQREDLE 808
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1664 4.67e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 91.74  E-value: 4.67e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  959 REAEQMGGELERLRAALMQSQGQQQEVRGQQER----EVARLTQERGQAQADLAQEKAAKAELEMRLQNTlneQRVEFAA 1034
Cdd:PTZ00121  1088 RADEATEEAFGKAEEAKKTETGKAEEARKAEEAkkkaEDARKAEEARKAEDARKAEEARKAEDAKRVEIA---RKAEDAR 1164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1035 LQEALTHAmteKEGKDQELAKlREQEAAQISELKALQQTLEELKKKEKEHPTggaRGEDASGDGPGSQLHTPGKTE-APG 1113
Cdd:PTZ00121  1165 KAEEARKA---EDAKKAEAAR-KAEEVRKAEELRKAEDARKAEAARKAEEER---KAEEARKAEDAKKAEAVKKAEeAKK 1237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1114 PEVEALRAEisKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARElghnQAASASAQRELQALRAKA 1193
Cdd:PTZ00121  1238 DAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKA 1311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1194 QDHSKAEE--------EWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvaESEKSQKLEERLRL 1265
Cdd:PTZ00121  1312 EEAKKADEakkkaeeaKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK----EEAKKKADAAKKKA 1387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1266 LQVETASSSARAAERSSALREEVQslREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHT 1345
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELK--KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1346 STQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAA-GGLQAELMRAQRELGELGSLRQkiVEQERAAQQLR-AE 1423
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAeAKKKADEAKKAEEAKKADEAKK--AEEAKKADEAKkAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1424 KASYAEQLSM---LKKAHGLL-AEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAETHLAEMRQEAqstsrel 1499
Cdd:PTZ00121  1544 EKKKADELKKaeeLKKAEEKKkAEEAKKAEEDKNMALRKAE-EAKKAEEARIEEVMKLYEEEKKMKAEEAKKA------- 1615

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1500 evmtakyESAKVKVlEERQRFQEERQKltaqVEQLEVFHREQTKQVEELNKKltESEQASRVQQQKLKAFQAqggesqqe 1579
Cdd:PTZ00121  1616 -------EEAKIKA-EELKKAEEEKKK----VEQLKKKEAEEKKKAEELKKA--EEENKIKAAEEAKKAEED-------- 1673

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1580 vqclQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQlqdlEQLQKDNKELRSETERLGRELQQAGLK 1659
Cdd:PTZ00121  1674 ----KKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA----EELKKAEEENKIKAEEAKKEAEEDKKK 1745


                   ....*
gi 1958645956 1660 TKEAE 1664
Cdd:PTZ00121  1746 AEEAK 1750
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1151-1656 8.58e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.38  E-value: 8.58e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1151 RAEQDKALETLQGQ---------LEEKARELGHNQAASA--SAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSS 1219
Cdd:COG1196    195 LGELERQLEPLERQaekaeryreLKEELKELEAELLLLKlrELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1220 LISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSAR---AAERSSALREEVQSLREEVE 1296
Cdd:COG1196    275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEleeLEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1297 KQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFR 1376
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1377 EEIEQSKQAAGGLQAELMRAQRELGEL----GSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERA 1452
Cdd:COG1196    435 EEEEEEEEALEEAAEEEAELEEEEEALlellAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1453 NLGRQF-------------------LEVELDQAREKYVQELAAVRTDAETHLAEmRQEAQSTSRELEVMTAKYESAKVKV 1513
Cdd:COG1196    515 LLAGLRglagavavligveaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKA-AKAGRATFLPLDKIRARAALAAALA 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1514 LEERQRF-------QEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQ 1586
Cdd:COG1196    594 RGAIGAAvdlvasdLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA 673

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1587 LSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQA 1656
Cdd:COG1196    674 LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 456-1266 2.89e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.89e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  456 EEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAqLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQE 535
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  536 QEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKeqeaaRQDHAQQLATIVEAREASVRERdaaRQQLETLEKEKDAKLESLQ 615
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELES-----KLDELAEELAELEEKLEELKEE---LESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  616 QQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATER--EKVVQEKVQ 693
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAelEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  694 LQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAeTRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQ 773
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  774 AETEalrHELAGATAAQHGAESereQLLREVESWQKRVEARQQEEARYGAMFqeqlmalkgehgkigqeeqkEAGEIHGE 853
Cdd:TIGR02168  531 VDEG---YEAAIEAALGGRLQA---VVVENLNAAKKAIAFLKQNELGRVTFL--------------------PLDSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  854 GQTGQQQSQLAQLHACLAKALQQVqEKEARAQKLLDDLSA-------------LREKMAATNKEVAcLKALVLKAGEQQA 920
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLV-KFDPKLRKALSYLLGgvlvvddldnaleLAKKLRPGYRIVT-LDGDLVRPGGVIT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  921 AAShelkEPPRAGNQESDWE--------EEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEvrgqQERE 992
Cdd:TIGR02168  663 GGS----AKTNSSILERRREieeleekiEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA----LRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  993 VARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALthamTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1073 TLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRA 1152
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1153 EQDKALETLQGQLEEKARELGhnqaasaSAQRELQALRAKAQDHSKAEEEWKAQVAR--------GQQEAERKSSLISSL 1224
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRS-------ELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeYSLTLEEAEALENKI 963

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1958645956 1225 EEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL 1266
Cdd:TIGR02168  964 EDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFL 1005
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1003-1682 1.65e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 1.65e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1003 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALTHA-----MTEKEGKDQELAKLREQEAAQISELKALQQTL 1074
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1075 EELKKKEKEHPTGGARGEDASGDGPGsqlhtpgkteapgpEVEALRAEISKLERQWQQQQQQVEGLTHSLEseracraEQ 1154
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK--------------ELYALANEISRLEQQKQILRERLANLERQLE-------EL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1155 DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNrq 1234
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-- 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1235 vlekegeskelKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAE 1314
Cdd:TIGR02168  400 -----------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1315 RAEESGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREEIEQSKQAAGG--L 1389
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGgrL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1390 QAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM----------- 1433
Cdd:TIGR02168  548 QAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1434 ---LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKyVQELAAVRTDAETHLAEMRQE 1491
Cdd:TIGR02168  628 vddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEK-IEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1492 AQSTSRELEVMTAKYESAKVKVLEER---QRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKA 1568
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1569 FQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQD-----------LEQLQK 1637
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEElsedieslaaeIEELEE 866

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1958645956 1638 DNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQAS 1682
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 412-1072 2.02e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 2.02e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  412 QLDTLKQEAaKLATDNTELQARVETLEC--------ERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEEL 483
Cdd:TIGR02168  201 QLKSLERQA-EKAERYKELKAELRELELallvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  484 QQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQML---QTLQEQEQAAQGLRQQVEQLSSSLKLKEQQ 560
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleSKLDELAEELAELEEKLEELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  561 LEEAAkeqeAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEkdakLESLQQQLQASNEARDTAQTSVTQAQREKA 640
Cdd:TIGR02168  360 LEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLNNE----IERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  641 ElsQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAA 720
Cdd:TIGR02168  432 E--AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  721 DALKEQQRHATemeaetrHLMEQREQEQKELEQEKAERKGLEARLQQL----EEAHQAETEALRHELAGATA-------- 788
Cdd:TIGR02168  510 ALLKNQSGLSG-------ILGVLSELISVDEGYEAAIEAALGGRLQAVvvenLNAAKKAIAFLKQNELGRVTflpldsik 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  789 AQHGAESEREQL---------LREVESWQKRVEA-------------------RQQEEARYGAMFQEQLMALKGEHGKI- 839
Cdd:TIGR02168  583 GTEIQGNDREILkniegflgvAKDLVKFDPKLRKalsyllggvlvvddldnalELAKKLRPGYRIVTLDGDLVRPGGVIt 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  840 GQEEQKEAG------EI-HGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALV 912
Cdd:TIGR02168  663 GGSAKTNSSilerrrEIeELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  913 LKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVR---GQQ 989
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNeeaANL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  990 EREVARLTQERGQAQA---DLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISE 1066
Cdd:TIGR02168  823 RERLESLERRIAATERrleDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902


                   ....*.
gi 1958645956 1067 LKALQQ 1072
Cdd:TIGR02168  903 LRELES 908
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 841-1404 2.48e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.76  E-value: 2.48e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  841 QEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQA 920
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  921 AASHELKEppragnqesdWEEEQARpLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQER 1000
Cdd:COG1196    320 ELEEELAE----------LEEELEE-LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1001 GQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKK 1080
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1081 EKEHPTGGARGEDAsgDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQqqveGLTHSLESERACRAEQDKALET 1160
Cdd:COG1196    469 LEEAALLEAALAEL--LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR----GLAGAVAVLIGVEAAYEAALEA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1161 -LQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKE 1239
Cdd:COG1196    543 aLAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1240 GESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEES 1319
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1320 GQELKawqekffQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRE 1399
Cdd:COG1196    703 EEEER-------ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775


                   ....*
gi 1958645956 1400 LGELG 1404
Cdd:COG1196    776 IEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 265-943 2.90e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.96  E-value: 2.90e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  265 KQAASPQEPSELEELRGKNESLTV----RLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfn 340
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-- 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  341 dliEEHSKASQEWAEKQAHLESELSTALQDKKCLEE--KSEILQEKISQLEDRAAQLQgspapEKGEVLGDALQLDTLKQ 418
Cdd:PTZ00121  1281 ---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAEEAKKKADAAK-----KKAEEAKKAAEAAKAEA 1352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  419 EAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQL 498
Cdd:PTZ00121  1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKK 1432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  499 ASLTALNATLQQQDQELTSLKEQAKKeqAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQ 578
Cdd:PTZ00121  1433 ADEAKKKAEEAKKADEAKKKAEEAKK--AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  579 LATivEAREAS-VRERDAARQQLETLEKEKDAKLESLQQ--QLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEA 655
Cdd:PTZ00121  1511 KAD--EAKKAEeAKKADEAKKAEEAKKADEAKKAEEKKKadELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKK 1588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  656 AHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKivrGSLEEEKCRAADALKEQQRHATEMEA 735
Cdd:PTZ00121  1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK---KKEAEEKKKAEELKKAEEENKIKAAE 1665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  736 ETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQ 815
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  816 QEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALR 895
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSK 1825

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 1958645956  896 EKMAATNKEVACLKALVL-KAGEQQAAASHELKEPPRAGNQESDWEEEQ 943
Cdd:PTZ00121  1826 EMEDSAIKEVADSKNMQLeEADAFEKHKFNKNNENGEDGNKEADFNKEK 1874
PTZ00121 PTZ00121
MAEBL; Provisional
 1147-1666 6.19e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.81  E-value: 6.19e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1147 ERACRAEQDKALETLQGQLE-EKARELGH-NQAASASAQRELQALRaKAQDHSKAEEEWKAQVARGQQEAERKSSLISSL 1224
Cdd:PTZ00121  1167 EEARKAEDAKKAEAARKAEEvRKAEELRKaEDARKAEAARKAEEER-KAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKA 1245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1225 EEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSAlrEEVQSLREEVEKQRVVSEN 1304
Cdd:PTZ00121  1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA--DEAKKKAEEAKKADEAKKK 1323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1305 lRQELASQAERAEESGQELKAWQEKFFQKEQAlSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQ 1384
Cdd:PTZ00121  1324 -AEEAKKKADAAKKKAEEAKKAAEAAKAEAEA-AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAE 1401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1385 AAGGLQAELMRAQRELGELGSLRQKIVEQERAAQ-QLRAEKASYAEQLSmlKKAHGLLAEENrgLGERANLGRQFLEVEL 1463
Cdd:PTZ00121  1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEaKKKAEEAKKADEAK--KKAEEAKKAEE--AKKKAEEAKKADEAKK 1477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1464 DQAREKYVQELAAVRTDAETHLAEMRQ--EAQSTSRELEVMTAKYESAKVKVLEERQ-----RFQEERQKLTAQVEQLEV 1536
Cdd:PTZ00121  1478 KAEEAKKADEAKKKAEEAKKKADEAKKaaEAKKKADEAKKAEEAKKADEAKKAEEAKkadeaKKAEEKKKADELKKAEEL 1557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1537 FHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQggesQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYD 1616
Cdd:PTZ00121  1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR----IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1617 AKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQA 1666
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA 1683
PTZ00121 PTZ00121
MAEBL; Provisional
 343-1072 6.40e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.81  E-value: 6.40e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  343 IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEvlgDALQLDTLKQEAAK 422
Cdd:PTZ00121  1111 AEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE---DAKKAEAARKAEEV 1187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  423 LATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLT 502
Cdd:PTZ00121  1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR 1267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  503 ALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQgLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQlati 582
Cdd:PTZ00121  1268 RQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE-AKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAK---- 1342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  583 vEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQT--SVTQAQREKAELSQKIGELHACIEA---AH 657
Cdd:PTZ00121  1343 -KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEkkKADEAKKKAEEDKKKADELKKAAAAkkkAD 1421

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  658 QEQRQAQAHVTELEAQLKAEQ-QKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQqrhATEMEAE 736
Cdd:PTZ00121  1422 EAKKKAEEKKKADEAKKKAEEaKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKK---AEEAKKK 1498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  737 TRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVE----------- 805
Cdd:PTZ00121  1499 ADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEeakkaeedknm 1578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  806 SWQKRVEARQQEEARYGAMFQ--EQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQE---- 879
Cdd:PTZ00121  1579 ALRKAEEAKKAEEARIEEVMKlyEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKaeee 1658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  880 ----KEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAalk 955
Cdd:PTZ00121  1659 nkikAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEA--- 1735

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  956 avQREAEQMGGELERLRaalmQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAE-LEMRLQNTLNEQRVEFAA 1034
Cdd:PTZ00121  1736 --KKEAEEDKKKAEEAK----KDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEkRRMEVDKKIKDIFDNFAN 1809

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1958645956 1035 LQEA----LTHAMTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:PTZ00121  1810 IIEGgkegNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEK 1851
PTZ00121 PTZ00121
MAEBL; Provisional
 942-1648 2.55e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.41  E-value: 2.55e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  942 EQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQ-QEVRGQQE---REVARLTQERGQAQADLAQEKAAKAEL 1017
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKaEEARKAEDakrVEIARKAEDARKAEEARKAEDAKKAEA 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1018 EMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKlREQEAAQISELKALQQTLEELKKKEKEHPTggaRGEDASGD 1097
Cdd:PTZ00121  1181 ARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEAR-KAEDAKKAEAVKKAEEAKKDAEEAKKAEEE---RNNEEIRK 1256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1098 GPGSQLHTPGKTEAPGPEVEALRA-EISKLERQWqqqqqqveglthslESERACRAEQDKALETLQGQLEEKaRELGHNQ 1176
Cdd:PTZ00121  1257 FEEARMAHFARRQAAIKAEEARKAdELKKAEEKK--------------KADEAKKAEEKKKADEAKKKAEEA-KKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1177 AASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvAESEKS 1256
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKK 1398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1257 QKLEERLRLLQVETASSSARAAERSSALREEVQ---SLREEVEKQRVVSE-NLRQELASQAERAEESGQELKAWQEKFFQ 1332
Cdd:PTZ00121  1399 KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKkadEAKKKAEEAKKADEaKKKAEEAKKAEEAKKKAEEAKKADEAKKK 1478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1333 KEQALSALQLEHTSTQAL--VSELLPAKHLCQQLQAEQAAAEKRFREEI---EQSKQAAGGLQAELMRAQRELGELGSLR 1407
Cdd:PTZ00121  1479 AEEAKKADEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAEEAKKADEAkkaEEAKKADEAKKAEEKKKADELKKAEELK 1558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1408 Q----KIVEQERAAQQLRAEKASYAEQLSMLKKAH-----GLLAEENRGLGERANLGRQFL----EVELDQAREKYVQEL 1474
Cdd:PTZ00121  1559 KaeekKKAEEAKKAEEDKNMALRKAEEAKKAEEARieevmKLYEEEKKMKAEEAKKAEEAKikaeELKKAEEEKKKVEQL 1638

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1475 AAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQlevfhREQTKQVEELNKKLTE 1554
Cdd:PTZ00121  1639 KKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKE-----AEEAKKAEELKKKEAE 1713

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1555 seqasrvqqQKLKAFQAQGGESQQEVQCLQTQLSELQaqlsQKEQAAEHYKLQMEKAKTHYDAKKQQN--QELREQLQDL 1632
Cdd:PTZ00121  1714 ---------EKKKAEELKKAEEENKIKAEEAKKEAEE----DKKKAEEAKKDEEEKKKIAHLKKEEEKkaEEIRKEKEAV 1780

                          730
                   ....*....|....*...
gi 1958645956 1633 --EQLQKDNKELRSETER 1648
Cdd:PTZ00121  1781 ieEELDEEDEKRRMEVDK 1798
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 335-1313 5.13e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.19  E-value: 5.13e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  335 LQGAFNDLIEEHSKASQEWAEKQA---HLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPApekgevlgDAL 411
Cdd:TIGR02169  140 LQGDVTDFISMSPVERRKIIDEIAgvaEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--------KAE 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  412 QLDTLKQEaaKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQG 491
Cdd:TIGR02169  212 RYQALLKE--KREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  492 AQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSsslKLKEQqleeaakeqeaa 571
Cdd:TIGR02169  290 LRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER---KRRDK------------ 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  572 rqdhaqqLATIVEAREAsvrERDAARQQLETLEKEKDA---KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGE 648
Cdd:TIGR02169  355 -------LTEEYAELKE---ELEDLRAELEEVDKEFAEtrdELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  649 LHACIEAAHQEQRQAQAHVTELEAQLKAEQQKateREKVVQEKVQLQEQLQALEETLKIVRgsleeekcraaDALKEQQR 728
Cdd:TIGR02169  425 LNAAIAGIEAKINELEEEKEDKALEIKKQEWK---LEQLAADLSKYEQELYDLKEEYDRVE-----------KELSKLQR 490

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  729 HATEMEAETRHLMEQREQEQKELEQEKAERKG---LEARLQQLEEAHQAETE-ALRHELAGATAAQHGAESEREQLLREV 804
Cdd:TIGR02169  491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgTVAQLGSVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRR 570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  805 eswqkrvearqqeeaRYGAMFQEQLMALKgehgkigqEEQKEAGEIHGEGQTGQQQSqLAQLHACLAKALQQVqekeARA 884
Cdd:TIGR02169  571 ---------------KAGRATFLPLNKMR--------DERRDLSILSEDGVIGFAVD-LVEFDPKYEPAFKYV----FGD 622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  885 QKLLDDLSALREKMAATNkevaclkaLVLKAGEqqaaasheLKEPPRAGNQESDweeeQARPLGSTQAALKAVQREAEQM 964
Cdd:TIGR02169  623 TLVVEDIEAARRLMGKYR--------MVTLEGE--------LFEKSGAMTGGSR----APRGGILFSRSEPAELQRLRER 682

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  965 GGELERLRAALMQsqgqqqevrgqqerEVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQrvefAALQEALTHAMT 1044
Cdd:TIGR02169  683 LEGLKRELSSLQS--------------ELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE----EKLKERLEELEE 744

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1045 EKEGKDQELAKLREQEAAQISELKALQQtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEIS 1124
Cdd:TIGR02169  745 DLSSLEQEIENVKSELKELEARIEELEE------------------------------------------DLHKLEEALN 782

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1125 KLERqwQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWK 1204
Cdd:TIGR02169  783 DLEA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLN 860

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1205 AQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSAL 1284
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK 940

                          970       980
                   ....*....|....*....|....*....
gi 1958645956 1285 REEVQSLREEVEKQRVVSENLRQELASQA 1313
Cdd:TIGR02169  941 GEDEEIPEEELSLEDVQAELQRVEEEIRA 969
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 938-1701 1.16e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.02  E-value: 1.16e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  938 DWEEEQARpLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLtQERGQAQADLAQEKAAKAEL 1017
Cdd:TIGR02168  233 RLEELREE-LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL-YALANEISRLEQQKQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1018 EMRLQNT---LNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDA 1094
Cdd:TIGR02168  311 LANLERQleeLEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1095 sgdgpgsqlhtpgkteaPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERacRAEQDKALETLQGQLEEKARELGH 1174
Cdd:TIGR02168  391 -----------------LELQIASLNNEIERLEARLERLEDRRERLQQEIEELL--KKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1175 NQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAErksslissleeevsILNRQVLEKEGESKELKRLVVAESE 1254
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD--------------SLERLQENLEGFSEGVKALLKNQSG 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1255 KSQKLEERLRLLQVETASSSARAAerssALREEVQSLreevekqrVVSENLRQELASQAERAEESGQ----ELKAWQEKF 1330
Cdd:TIGR02168  518 LSGILGVLSELISVDEGYEAAIEA----ALGGRLQAV--------VVENLNAAKKAIAFLKQNELGRvtflPLDSIKGTE 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1331 FQKEQALSALQLEHTSTQALVSELLPAK-HLCQQLQAEQAAAEKRFREEIEQSKQAAGG-----LQAELMR--------- 1395
Cdd:TIGR02168  586 IQGNDREILKNIEGFLGVAKDLVKFDPKlRKALSYLLGGVLVVDDLDNALELAKKLRPGyrivtLDGDLVRpggvitggs 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1396 AQRELG------ELGSLRQKIVEQERAAQQLRAEKASYAEQLS----MLKKAHGLLAEENRGLGE-RANLGRQFLEVELD 1464
Cdd:TIGR02168  666 AKTNSSilerrrEIEELEEKIEELEEKIAELEKALAELRKELEeleeELEQLRKELEELSRQISAlRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1465 QAR----EKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERqkltAQVEQLEVFHRE 1540
Cdd:TIGR02168  746 EERiaqlSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR----AELTLLNEEAAN 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1541 QTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQ 1620
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1621 QNQELREQLQDLEQlqkDNKELRSETERLgrELQQAGLKTKEAEQACRHLTAQVRSLEAQASFYF--TSKVAHADQQLRD 1698
Cdd:TIGR02168  902 ELRELESKRSELRR---ELEELREKLAQL--ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENkiEDDEEEARRRLKR 976


                   ...
gi 1958645956 1699 LGK 1701
Cdd:TIGR02168  977 LEN 979
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 755-1652 3.00e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 3.00e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  755 KAER-KGLEARLQQLE--------EAHQAETEALRHELAGATAAQHGAESEREQLLREVESwqkRVEARQQEEARYGAMF 825
Cdd:TIGR02169  209 KAERyQALLKEKREYEgyellkekEALERQKEAIERQLASLEEELEKLTEEISELEKRLEE---IEQLLEELNKKIKDLG 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  826 QEQLMALKGEHGKIgqeeqkeageihgegqtgqqQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEV 905
Cdd:TIGR02169  286 EEEQLRVKEKIGEL--------------------EAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREI 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  906 ACLKALVLKAGEQQAAASHELKEppragnQESDWEEEQARpLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQev 985
Cdd:TIGR02169  346 EEERKRRDKLTEEYAELKEELED------LRAELEEVDKE-FAETRDELKDYREKLEKLKREINELKRELDRLQEELQ-- 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  986 rgqqerevaRLTQERGQAQADLAQEKAAKAELEMRLqntlneqrvefaalqEALTHAMTEKEGKDQELAKLREQEAAQIS 1065
Cdd:TIGR02169  417 ---------RLSEELADLNAAIAGIEAKINELEEEK---------------EDKALEIKKQEWKLEQLAADLSKYEQELY 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1066 ELKAlqqtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEISKLERQWQQQQQQVEGLTHSLE 1145
Cdd:TIGR02169  473 DLKE---------------------------------------------EYDRVEKELSKLQRELAEAEAQARASEERVR 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1146 SERACRAEQDKALETLQGQLEEKAR-ELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQ------QEAERKS 1218
Cdd:TIGR02169  508 GGRAVEEVLKASIQGVHGTVAQLGSvGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplNKMRDER 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1219 SLISSLEEEVSI---LNRQVLEKEGESKEL----KRLVVAESEKSQKLEERLRLLQVET------------ASSSARAAE 1279
Cdd:TIGR02169  588 RDLSILSEDGVIgfaVDLVEFDPKYEPAFKyvfgDTLVVEDIEAARRLMGKYRMVTLEGelfeksgamtggSRAPRGGIL 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1280 RSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKH 1359
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS 747

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1360 LCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGelgslRQKIVEQERAAQQLRAEKASYAEQLSMLKkahg 1439
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS-----HSRIPEIQAELSKLEEEVSRIEARLREIE---- 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1440 llAEENRGLGERANLgrqfleveldqarEKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLE---E 1516
Cdd:TIGR02169  819 --QKLNRLTLEKEYL-------------EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDlesR 883

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1517 RQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTqLSELQAQLSQ 1596
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-LEDVQAELQR 962

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956 1597 KEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRE 1652
Cdd:TIGR02169  963 VEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
HkD_SF cd22211
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
 8-136 5.69e-13

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


Pssm-ID: 411792  Cd Length: 145  Bit Score: 68.07  E-value: 5.69e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956    8 ASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSI---HDTKEGQQILQQPLP-----ERLDFVCSFLQKNRKH----P 75
Cdd:cd22211      1 EAALLAWINTFPLSSPVESLDDLSDGVVLAEILSQIdpsYFDSEWLESRDSSDNwvlklNNLKKLYRSLSKYYREvlgqQ 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956   76 SSTQCLVSVQKVME-GSEMELAKMVMLFLYHSTMSSRNPRD---WEQFEYGVQAELAVILKFMLD 136
Cdd:cd22211     81 LSDLPLPDLSAIARdGDEEEIVKLLELVLGAAVQCENKEEYiarIQQLDESTQAELMLIIQEVLE 145
PTZ00121 PTZ00121
MAEBL; Provisional
 514-1252 6.34e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.79  E-value: 6.34e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  514 ELTSLKEQAKK--EQAQMLQTLQEQEQA--AQGLRQQVEQLSSSLKLKEQ---QLEEAAKEQEAARQDHAQQLATIVEAR 586
Cdd:PTZ00121  1112 EEARKAEEAKKkaEDARKAEEARKAEDArkAEEARKAEDAKRVEIARKAEdarKAEEARKAEDAKKAEAARKAEEVRKAE 1191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  587 EasVRERDAARQQLETLEKEKDAKLESLQQqlqaSNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQaQAH 666
Cdd:PTZ00121  1192 E--LRKAEDARKAEAARKAEEERKAEEARK----AEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR-MAH 1264

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  667 VTELEAQLKAEQQKATEREKVVQEKVQlQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRhlmeqreq 746
Cdd:PTZ00121  1265 FARRQAAIKAEEARKADELKKAEEKKK-ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAK-------- 1335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  747 eqkeleqEKAERKglearlQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRV-EARQQEEARYGAMF 825
Cdd:PTZ00121  1336 -------KKAEEA------KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAeEKKKADEAKKKAEE 1402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  826 QEQlmalKGEHGKIGQEEQKEAGEIHGEGQTGQQqsqlaqlhaclAKALQQVQEKEARAQKLLDDLSALREKMAATNKEV 905
Cdd:PTZ00121  1403 DKK----KADELKKAAAAKKKADEAKKKAEEKKK-----------ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  906 ACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQ-REAEQMGGELERLRAALMQSQGQQQE 984
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEaKKADEAKKAEEAKKADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  985 VRGQQEREVARLTQERGQAQadlaQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKlREQEAAQI 1064
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAE----EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK-AEEAKIKA 1622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1065 SELKALQQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTpgKTEAPGPEVEALRAEisKLERQWQQQQQQVEGLTHsl 1144
Cdd:PTZ00121  1623 EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA--AEEAKKAEEDKKKAE--EAKKAEEDEKKAAEALKK-- 1696

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1145 ESERACRAEQ-DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEwKAQVARGQQEAERKSsliss 1223
Cdd:PTZ00121  1697 EAEEAKKAEElKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKA----- 1770

                          730       740
                   ....*....|....*....|....*....
gi 1958645956 1224 leEEVSILNRQVLEKEGESKELKRLVVAE 1252
Cdd:PTZ00121  1771 --EEIRKEKEAVIEEELDEEDEKRRMEVD 1797
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1373-1681 9.90e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 9.90e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1373 KRFREEIEQSKQAAGGLQAELMRAQRELgelgsLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERa 1452
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEE-----LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAE- 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1453 nlgrqflEVELDQAREKYVQELAavrtdaetHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVE 1532
Cdd:COG1196    290 -------EYELLAELARLEQDIA--------RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1533 QLEvfhreqtKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAK 1612
Cdd:COG1196    355 EAE-------AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956 1613 thyDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQA 1681
Cdd:COG1196    428 ---EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 874-1647 7.18e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 7.18e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  874 LQQVQEKEARAQKLLDDLSALREKMAaTNKEVAcLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEqarpLGSTQAA 953
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLR-REREKA-ERYQALLKEKREYEGYELLKEKEALERQKEAIERQ----LASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  954 LKAVQREAEQMGGELERLRAALMQsqgQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFA 1033
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEE---LNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1034 ALQEALThamtEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASgdgpgSQLHTpgKTEAPG 1113
Cdd:TIGR02169  330 EIDKLLA----EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL-----KDYRE--KLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1114 PEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKA 1193
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1194 QDHSKAEEEWKAQVARgqQEAERKsslISSLEEEVSILNRQVLEK--EGESKELKRLVVAESEKSQKLE----ERLRLLQ 1267
Cdd:TIGR02169  479 DRVEKELSKLQRELAE--AEAQAR---ASEERVRGGRAVEEVLKAsiQGVHGTVAQLGSVGERYATAIEvaagNRLNNVV 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1268 VETASSSARAAE---RSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQL-- 1342
Cdd:TIGR02169  554 VEDDAVAKEAIEllkRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAar 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1343 EHTSTQALVS---ELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQaaggLQAELMRAQRELGelgSLRQKIVEQERAAQQ 1419
Cdd:TIGR02169  634 RLMGKYRMVTlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELS---SLQSELRRIENRLDE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1420 LRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDaethLAEMRQEAQSTSREL 1499
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-SLEQEIENVKSELKELEAR----IEELEEDLHKLEEAL 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1500 EVMTAKYESAKVKVLEERQRFQEE-RQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQ 1578
Cdd:TIGR02169  782 NDLEARLSHSRIPEIQAELSKLEEeVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNG 861

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956 1579 EVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETE 1647
Cdd:TIGR02169  862 KKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
243-738 1.03e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 1.03e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  243 TEKDAQIAMMQQRIDHlALLNEKQAASPQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  383 EKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  463 ASLVADLQSSVSNLSQAKEELQ--------------------QASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  523 K-----KEQAQMLQ--------TLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQeaarQDHAQQLATIVEAREas 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA----EEAREEVAELNSKLA-- 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  590 vrERDAARQQLETLEkEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELH-----ACIEAAHQEQRQAQ 664
Cdd:PRK02224   583 --ELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEaefdeARIEEAREDKERAE 659

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645956  665 AHVTELEAQLkaeQQKATEREKVVQEKVQLQEQLQALEEtLKIVRGSLeEEKCRAADALKEQQRHATEMEAETR 738
Cdd:PRK02224   660 EYLEQVEEKL---DELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLR 728
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 374-771 1.40e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.40e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  374 LEEKSEI--LQEKISQLEDRAAQLQgspapekgevlgdaLQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAe 451
Cdd:TIGR02168  673 LERRREIeeLEEKIEELEEKIAELE--------------KALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR- 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  452 rghFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQmlq 531
Cdd:TIGR02168  738 ---LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE--- 811

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  532 tLQEQEQAAQGLRQQVEQLSSSLKLKEQQLeeaakeqeaarQDHAQQLATIVEAREASVRERDAARQQLETLEKEkdakL 611
Cdd:TIGR02168  812 -LTLLNEEAANLRERLESLERRIAATERRL-----------EDLEEQIEELSEDIESLAAEIEELEELIEELESE----L 875

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  612 ESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATER-----EK 686
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltlEE 955

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  687 VVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQrhatemEAETRHlmeqreqeqkelEQEKAERKGLEARLQ 766
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYE------ELKERY------------DFLTAQKEDLTEAKE 1017


                   ....*
gi 1958645956  767 QLEEA 771
Cdd:TIGR02168 1018 TLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1115-1680 3.92e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 3.92e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:TIGR02169  295 KIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1195 DHSKAEEEWKAQVargqqeaerkssliSSLEEEVSILNRqvlekegESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:TIGR02169  375 EVDKEFAETRDEL--------------KDYREKLEKLKR-------EINELKRELDRLQEELQRLSEELADLNAAIAGIE 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1275 ARAAErssaLREEVQSLREEVEKQRvvsenlrqelasqaERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:TIGR02169  434 AKINE----LEEEKEDKALEIKKQE--------------WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1355 LPAKhlcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQR------ELGELGSLRQKIVEQE----RAAQQLRAEK 1424
Cdd:TIGR02169  496 EAQA----RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGEryataiEVAAGNRLNNVVVEDDavakEAIELLKRRK 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1425 ASYAEQLSMLKKAHGLLaeENRGLGERANLGRQFLEVELDQARE---KYVQELAAVRTDAETHLAEMRQ----------- 1490
Cdd:TIGR02169  572 AGRATFLPLNKMRDERR--DLSILSEDGVIGFAVDLVEFDPKYEpafKYVFGDTLVVEDIEAARRLMGKyrmvtlegelf 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1491 ------EAQSTSRELEVMTAKYESAKVKVLEER--------QRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESE 1556
Cdd:TIGR02169  650 eksgamTGGSRAPRGGILFSRSEPAELQRLRERleglkrelSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1557 QASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDakKQQNQELREQLQDLEqlq 1636
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS--HSRIPEIQAELSKLE--- 804

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1958645956 1637 KDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQ 1680
Cdd:TIGR02169  805 EEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ 848
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 591-1551 8.82e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 8.82e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  591 RERDAARQQLETLEK---EKDAKLESLQQQLQAsneardtaqtsvTQAQREKAELSQKIgelhacieaahqeqrqaQAHV 667
Cdd:TIGR02169  170 RKKEKALEELEEVEEnieRLDLIIDEKRQQLER------------LRREREKAERYQAL-----------------LKEK 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  668 TELEAQLKAEQQKATEREKVvqekvQLQEQLQALEEtlkivrgSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQE 747
Cdd:TIGR02169  221 REYEGYELLKEKEALERQKE-----AIERQLASLEE-------ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE 288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  748 QKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEearygamfqe 827
Cdd:TIGR02169  289 QLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEE---------- 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  828 qlmalkgehgkigqeeqkeageihgegqtgqqqsqLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVAC 907
Cdd:TIGR02169  359 -----------------------------------YAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE 403

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  908 LKALVLKAGEQQAAASHELKEpprAGNQESDWEEEQArplgSTQAALKAVQREAEQMGGELERLraalmqsqgqqQEVRG 987
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELAD---LNAAIAGIEAKIN----ELEEEKEDKALEIKKQEWKLEQL-----------AADLS 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  988 QQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRvEFAALQEALTHAMTEKEGKDQELAKLREQ-----EAA 1062
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVR-GGRAVEEVLKASIQGVHGTVAQLGSVGERyataiEVA 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1063 QISELKAL----QQTLEELKKKEKEHPTGGAR----GEDASGDGPGSQLHTPGkteapgpeVEALRAEISKLERQWQQQQ 1134
Cdd:TIGR02169  545 AGNRLNNVvvedDAVAKEAIELLKRRKAGRATflplNKMRDERRDLSILSEDG--------VIGFAVDLVEFDPKYEPAF 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1135 QQVEGLTHSLESERACRAEQDKA-LETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQE 1213
Cdd:TIGR02169  617 KYVFGDTLVVEDIEAARRLMGKYrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSE 696

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1214 AERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETA---SSSARAAERSSALREEVQS 1290
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvkSELKELEARIEELEEDLHK 776

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1291 LREEVEK-QRVVSENLRQELASQAERAEEsgqELKAWQEKFFQKEQALSALQLEHTSTQALVSELLpakhlcqQLQAEQA 1369
Cdd:TIGR02169  777 LEEALNDlEARLSHSRIPEIQAELSKLEE---EVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQ-------EQRIDLK 846

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1370 AAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGS-----------LRQKIVEQERAAQQLRAEKASYAEQLSMLKKAH 1438
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKEELEEELEELEAALRDLESrlgdlkkerdeLEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1439 GLLAEENRGLGERANLGRQFLEVELDqarekyvqelaavrtdaETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQ 1518
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEELS-----------------LEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLD 989

                          970       980       990
                   ....*....|....*....|....*....|...
gi 1958645956 1519 RFQEERQKLTAQVEQLevfhREQTKQVEELNKK 1551
Cdd:TIGR02169  990 ELKEKRAKLEEERKAI----LERIEEYEKKKRE 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1459-1713 1.15e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1459 LEVELDQAREKyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKY---ESAKVKVLEERQRFQEERQKLTAQVEQLE 1535
Cdd:COG1196    244 LEAELEELEAE-LEELEAELAELEAELEELRLELEELELELEEAQAEEyelLAELARLEQDIARLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1536 VFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHY 1615
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1616 DAKKQQNQELREQLQDLEQ----LQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQASFYFTSKVAH 1691
Cdd:COG1196    403 EELEEAEEALLERLERLEEeleeLEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260
                   ....*....|....*....|..
gi 1958645956 1692 ADQQLRDLGKFQVATDALKSRE 1713
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYE 504
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 244-908 1.48e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.02  E-value: 1.48e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  244 EKDAQIAMMQQRIDHLAL-LNEKQAASPQEPSELEELrGKNESLTVR-----LHETLKQCQNLKTEKN----QMDRKISQ 313
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKrLEEIEQLLEELNKKIKDL-GEEEQLRVKekigeLEAEIASLERSIAEKEreleDAEERLAK 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  314 LSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLEsELSTALQDkkcLEEKSEILQEKISQLEDRAA 393
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE-EVDKEFAE---TRDELKDYREKLEKLKREIN 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  394 QLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSV 473
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  474 SNLSQAKEELQQASQAQGAQLTAQL---ASLTALNATLQ---QQDQELTSLKEQAKKE---------QAQMLQTLQEQEQ 538
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEERVRggrAVEEVLKASIQgvhGTVAQLGSVGERYATAievaagnrlNNVVVEDDAVAKE 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  539 AAQGLRQqvEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLAT---------------------IVEAREA--------- 588
Cdd:TIGR02169  563 AIELLKR--RKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVdlvefdpkyepafkyvfgdtlVVEDIEAarrlmgkyr 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  589 ------------------SVRERDAARQQLETLEKEKD--AKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGE 648
Cdd:TIGR02169  641 mvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRlrERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  649 LHACIEAAHQEQRQAQAHVTELEAQLKAEQQkatEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADA-LKEQQ 727
Cdd:TIGR02169  721 IEKEIEQLEQEEEKLKERLEELEEDLSSLEQ---EIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSrIPEIQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  728 RHATEMEaetrhlmeqreqeqkeleqekAERKGLEARLQQLEEAHQAET---EALRHELAGATAAQHGAESEREQLLREV 804
Cdd:TIGR02169  798 AELSKLE---------------------EEVSRIEARLREIEQKLNRLTlekEYLEKEIQELQEQRIDLKEQIKSIEKEI 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  805 ESWQKRVEARQQEEARYgamfQEQLMALKGEHGKIgQEEQKEAgeihgEGQTGQQQSQLAQLHACLAKALQQVQEKEARA 884
Cdd:TIGR02169  857 ENLNGKKEELEEELEEL----EAALRDLESRLGDL-KKERDEL-----EAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          730       740
                   ....*....|....*....|....
gi 1958645956  885 QKLLDDLSALREKMAATNKEVACL 908
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEE 950
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
577-1072 1.95e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 66.48  E-value: 1.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  577 QQLATIVEAREASVRerdaARQQLETLE--KEKDAKLESLQQQLQASNEARDT-----AQTSVTQAQREKAELSQKIGEL 649
Cdd:COG4913    232 EHFDDLERAHEALED----AREQIELLEpiRELAERYAAARERLAELEYLRAAlrlwfAQRRLELLEAELEELRAELARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  650 HACIEAAHQEQRQAQAHVTELEAQL-----KAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALK 724
Cdd:COG4913    308 EAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRA 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  725 EQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQ---AETEALRHELAGATAAqhgaeSERE--- 798
Cdd:COG4913    388 EAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSnipARLLALRDALAEALGL-----DEAElpf 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  799 -----QLLREVESWQKRVEA--RQQE-----EARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQ------- 859
Cdd:COG4913    463 vgeliEVRPEEERWRGAIERvlGGFAltllvPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSlagkldf 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  860 ---------QSQLAQL--HACL--AKALQ----------QVQEKEARAQKllDDLSALR----------EKMAATNKEVA 906
Cdd:COG4913    543 kphpfrawlEAELGRRfdYVCVdsPEELRrhpraitragQVKGNGTRHEK--DDRRRIRsryvlgfdnrAKLAALEAELA 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  907 CLKALVLKAGEQQAAASHELKEPPRAGN-----QESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQ 981
Cdd:COG4913    621 ELEEELAEAEERLEALEAELDALQERREalqrlAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAE 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  982 QQEVrgqqEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVE-FAALQEALthamtEKEGKDQELAKLREQE 1060
Cdd:COG4913    701 LEEL----EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLElRALLEERF-----AAALGDAVERELRENL 771

                          570
                   ....*....|..
gi 1958645956 1061 AAQISELKALQQ 1072
Cdd:COG4913    772 EERIDALRARLN 783
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 304-879 4.75e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 4.75e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  304 KNQMDRKISQLSeengDLSFKVREFANHLQQLQGAFNDLIEEhskasqewAEKQAHL-ESELSTALQDKKCLEEKS---- 378
Cdd:pfam15921  309 RNQNSMYMRQLS----DLESTVSQLRSELREAKRMYEDKIEE--------LEKQLVLaNSELTEARTERDQFSQESgnld 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  379 EILQEKISQLEDRAAQLQGSPAPEK---GEVLGDALQLDTLKQEAAKLATDNTELQARVETLECE-RGKQEAQLLAERGH 454
Cdd:pfam15921  377 DQLQKLLADLHKREKELSLEKEQNKrlwDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGK 456

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  455 fEEEKRQLASLVADLQSSVSNLSQAKEELqqasqaqgaqltaqlaslTALNATLQQQDQELTSLKeqakkeqaqmlQTLQ 534
Cdd:pfam15921  457 -NESLEKVSSLTAQLESTKEMLRKVVEEL------------------TAKKMTLESSERTVSDLT-----------ASLQ 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  535 EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeaarQDHAQQLATiveareasvrERDAARQQLetleKEKDAKLESL 614
Cdd:pfam15921  507 EKERAIEATNAEITKLRSRVDLKLQELQHLKNE-----GDHLRNVQT----------ECEALKLQM----AEKDKVIEIL 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  615 QQQLQASNEARDTAQTSVTQAQREKAELSQKIG-------ELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKV 687
Cdd:pfam15921  568 RQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINdrrlelqEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  688 VQEKVQLQEQLQALEETLKIVRGSLEEEkcraADALKEQQRHAT-EMEAETRHLmeqreqeqkeleqeKAERKGLEARLQ 766
Cdd:pfam15921  648 VKDIKQERDQLLNEVKTSRNELNSLSED----YEVLKRNFRNKSeEMETTTNKL--------------KMQLKSAQSELE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  767 QLEEAHQAETEALRHELAGATAAQHGAESEREQlLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKE 846
Cdd:pfam15921  710 QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ-IDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1958645956  847 AGEIHG-EGQTGQQQSQLAQLHACLAKALQQVQE 879
Cdd:pfam15921  789 AGELEVlRSQERRLKEKVANMEVALDKASLQFAE 822
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1221-1682 4.81e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 65.32  E-value: 4.81e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1221 ISSLEEEVSILNRQV--LEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERssALREEVQSLREEVEKQ 1298
Cdd:COG4913    237 LERAHEALEDAREQIelLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELE--ELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1299 RVVSENLRQELAS-QAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlQAEQAAAEKRFRE 1377
Cdd:COG4913    315 EARLDALREELDElEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL----------GLPLPASAEEFAA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1378 EIEQSKQAAGGLQAELMRAQRELGELgslRQKIVEQERAAQQLRAEKAS-----------YAEQLSMLKKAHGLLAEENR 1446
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEA---EAALRDLRRELRELEAEIASlerrksniparLLALRDALAEALGLDEAELP 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1447 GLGEranlgrqFLEVELDQAR--------------------EKYVQELAAV-RTDAETHL------------AEMRQEAQ 1493
Cdd:COG4913    462 FVGE-------LIEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVnRLHLRGRLvyervrtglpdpERPRLDPD 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1494 STSRELEVMTAKYESAKVKVLEERQRFqeerqkltAQVEQLEVFHRE--------QTKQVEELNKKLTESEQASRVQ--- 1562
Cdd:COG4913    535 SLAGKLDFKPHPFRAWLEAELGRRFDY--------VCVDSPEELRRHpraitragQVKGNGTRHEKDDRRRIRSRYVlgf 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1563 --QQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYK---------LQMEKAKTHYDAKKQQNQELREQLQD 1631
Cdd:COG4913    607 dnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeIDVASAEREIAELEAELERLDASSDD 686

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645956 1632 LEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQAS 1682
Cdd:COG4913    687 LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE 737
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1115-1656 2.06e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.01  E-value: 2.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERacRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRR--LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIR 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1195 DHS-KAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASS 1273
Cdd:COG4913    334 GNGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1274 SARAAERSSALREEVQSLReevekQRVVS-----ENLRQELASQAERAEES----------GQELKAWQEKFfqkEQALs 1338
Cdd:COG4913    414 LRDLRRELRELEAEIASLE-----RRKSNiparlLALRDALAEALGLDEAElpfvgelievRPEEERWRGAI---ERVL- 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1339 alqlehtSTQALvSELLPAKHLcqqlqaeqaaaeKRFREEIEQSKQaAGGLQAELMRAQRELGEL-----GSLRQKIV-- 1411
Cdd:COG4913    485 -------GGFAL-TLLVPPEHY------------AAALRWVNRLHL-RGRLVYERVRTGLPDPERprldpDSLAGKLDfk 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1412 --EQERAAQQLRAEKASYA-----EQLSMLKKA---HGLLAEE--------NRGLGERANLG------RQFLEVELDQAR 1467
Cdd:COG4913    544 phPFRAWLEAELGRRFDYVcvdspEELRRHPRAitrAGQVKGNgtrhekddRRRIRSRYVLGfdnrakLAALEAELAELE 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1468 EKyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKvlEERQRFQEERQKLTA---QVEQLEvfhreqtKQ 1544
Cdd:COG4913    624 EE-LAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAE--REIAELEAELERLDAssdDLAALE-------EQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1545 VEELNKKLTESEQASRVQQQKLkafqaqgGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQmekaktHYDAKKQQNQE 1624
Cdd:COG4913    694 LEELEAELEELEEELDELKGEI-------GRLEKELEQAEEELDELQDRLEAAEDLARLELRA------LLEERFAAALG 760

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1958645956 1625 LREQLQDLEQLQKDNKELRSETERLGRELQQA 1656
Cdd:COG4913    761 DAVERELRENLEERIDALRARLNRAEEELERA 792
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 275-1021 2.13e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 2.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  275 ELEELRGKNESLTVRLHETLKQCQNLKTEKNQmdrkisqlSEENGDLSFKVREFANHLqqLQGAFNDLIEEHSKASQEWA 354
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREK--------AERYQALLKEKREYEGYE--LLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  355 EKQAHLE---SELSTALQDKKCLEEKSEILQEKISQL-EDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAaklatdnTEL 430
Cdd:TIGR02169  248 SLEEELEkltEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKEREL-------EDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  431 QARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSvsnlsqaKEELqqasqaqgAQLTAQLASLTALNATLQQ 510
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL-------KEEL--------EDLRAELEEVDKEFAETRD 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  511 QDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHA---QQLATIVEARE 587
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKkqeWKLEQLAADLS 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  588 ASVRERDAARQQLETLEKEkdakLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEaahQEQRQAQAHV 667
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVA---QLGSVGERYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  668 TELEAQLKAEQQK-ATEREKVVQEKVQLQEQLQALEETL----KIVRGSLEEEKCR-------AADALKEQQRHAT---- 731
Cdd:TIGR02169  539 TAIEVAAGNRLNNvVVEDDAVAKEAIELLKRRKAGRATFlplnKMRDERRDLSILSedgvigfAVDLVEFDPKYEPafky 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  732 ---------EMEAETRHL------------------MEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELA 784
Cdd:TIGR02169  619 vfgdtlvveDIEAARRLMgkyrmvtlegelfeksgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELR 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  785 GATAAQHGAESEREQLLREVESWQKRVEARQQEEARygamFQEQLMALKGEHGKIGQE-EQKEAGEIHGEGQTGQQQSQL 863
Cdd:TIGR02169  699 RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK----LKERLEELEEDLSSLEQEiENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  864 AQLHACLAK-----ALQQVQEKEARAQKLLDDLSALREKMAATNKEvacLKALVLKAGEQQAAASHELKEPPRAGNQESD 938
Cdd:TIGR02169  775 HKLEEALNDlearlSHSRIPEIQAELSKLEEEVSRIEARLREIEQK---LNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  939 WEEEQArplgSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVR---GQQEREVARLTQERGQAQADLAQEKAAKA 1015
Cdd:TIGR02169  852 IEKEIE----NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEaqlRELERKIEELEAQIEKKRKRLSELKAKLE 927


                   ....*.
gi 1958645956 1016 ELEMRL 1021
Cdd:TIGR02169  928 ALEEEL 933
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1114-1659 3.00e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 3.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1114 PEVEALRAEISKLERQWQQQQQQVEGLThSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKA 1193
Cdd:PRK03918   214 SELPELREELEKLEKEVKELEELKEEIE-ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1194 QDHSKAEE---EWKAQVARGQQEAERKSSLISSLEEEVSILNrqvlEKEGESKELKRLVVAESEKSQKLEERLRLLqvet 1270
Cdd:PRK03918   293 EEYIKLSEfyeEYLDELREIEKRLSRLEEEINGIEERIKELE----EKEERLEELKKKLKELEKRLEELEERHELY---- 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1271 asssaraaERSSALREEVQSLREEVEKQRVvsENLRQELASQAERAEESGQELKAWQEKffqkeqaLSALQLEHTSTQAL 1350
Cdd:PRK03918   365 --------EEAKAKKEELERLKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITAR-------IGELKKEIKELKKA 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1351 VSELLPAKHLC-----QQLQAEQAAAEKRFREE---IEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRA 1422
Cdd:PRK03918   428 IEELKKAKGKCpvcgrELTEEHRKELLEEYTAElkrIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1423 ----------EKASY-AEQLSMLKKAHGLLAEENRGLGERANLGRQF------LEVELDQAREkyvqELAAVRTDAETHL 1485
Cdd:PRK03918   508 leeklkkynlEELEKkAEEYEKLKEKLIKLKGEIKSLKKELEKLEELkkklaeLEKKLDELEE----ELAELLKELEELG 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1486 AEMRQEAQSTSRELEVMTAKYESAKvKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQK 1565
Cdd:PRK03918   584 FESVEELEERLKELEPFYNEYLELK-DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYE 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1566 lkafqaqggESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKthydAKKQQNQELREQLQDLEQLQKDNKELRSE 1645
Cdd:PRK03918   663 ---------ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLK----EELEEREKAKKELEKLEKALERVEELREK 729

                          570
                   ....*....|....
gi 1958645956 1646 TERLGRELQQAGLK 1659
Cdd:PRK03918   730 VKKYKALLKERALS 743
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1213-1565 4.42e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 61.68  E-value: 4.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1213 EAERKSSLISSLEEEVSILNRQVLEKeGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLR 1292
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEK-FEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAME 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1293 EEVEKQRVVSENLRQELasQAERAEESGQELKAWQEkffqkeqaLSALQLEHTSTQALVSELLPAkhlcqqlqaeqaAAE 1372
Cdd:pfam17380  346 RERELERIRQEERKREL--ERIRQEEIAMEISRMRE--------LERLQMERQQKNERVRQELEA------------ARK 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1373 KRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSML-------KKAHGLLAEEN 1445
Cdd:pfam17380  404 VKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLrqqeeerKRKKLELEKEK 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1446 RGLGERANLGRQFLEVELDQAREKYVQElaavRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQ 1525
Cdd:pfam17380  484 RDRKRAEEQRRKILEKELEERKQAMIEE----ERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1958645956 1526 KLTAQVEQLEVFHREQ--TKQVEELNKKLTESEQASRVQQQK 1565
Cdd:pfam17380  560 KATEERSRLEAMERERemMRQIVESEKARAEYEATTPITTIK 601
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1174-1675 6.22e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 6.22e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1174 HNQAASASAQRE-LQALRAKAQDHSKAEEEwkaqvaRGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAE 1252
Cdd:COG4913    241 HEALEDAREQIElLEPIRELAERYAAARER------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1253 SEKSQKLEERLRLLQVETASSSARAAERssaLREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFfq 1332
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDRLEQ---LEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA-- 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1333 kEQALSALQLEHTSTQALVSELLPAKHlcqqlqaEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGE---------- 1402
Cdd:COG4913    390 -AALLEALEEELEALEEALAEAEAALR-------DLRRELRELEAEIASLERRKSNIPARLLALRDALAEalgldeaelp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1403 ----------------------LGSLRQKI-VEQERAAQQLRaekasYAEQLSMLKKAHGLLAEENRGLGERANLGRQFL 1459
Cdd:COG4913    462 fvgelievrpeeerwrgaiervLGGFALTLlVPPEHYAAALR-----WVNRLHLRGRLVYERVRTGLPDPERPRLDPDSL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1460 ----EVELDQAREkYVQELAAVRTDAE--THLAEMRQEAQSTSRELEVmtakYESAKVKVLEERQRFQEER---QKLTAQ 1530
Cdd:COG4913    537 agklDFKPHPFRA-WLEAELGRRFDYVcvDSPEELRRHPRAITRAGQV----KGNGTRHEKDDRRRIRSRYvlgFDNRAK 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1531 VEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQ--AQGGESQQEVQCLQTQLSELQAQ----------LSQKE 1598
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAElerldassddLAALE 691

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645956 1599 QAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVR 1675
Cdd:COG4913    692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELR 768
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1373-1713 8.73e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.23  E-value: 8.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1373 KRFREEIEQSKQAAGGLQAelMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgera 1452
Cdd:TIGR02168  213 ERYKELKAELRELELALLV--LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE-------- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1453 nlgrqfleveLDQAREKYvQELAAVRTDAETHLAEMRQEAQSTSRELEvmtaKYESAKVKVLEERQRFQEERQKLTAQVE 1532
Cdd:TIGR02168  283 ----------IEELQKEL-YALANEISRLEQQKQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEEKLE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1533 QLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQaqlSQKEQAAEHY-KLQMEKA 1611
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE---ARLERLEDRReRLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1612 KTHYDAKKQQNQELREQL----QDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEA---QASFY 1684
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELeeleEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqeNLEGF 504

                          330       340
                   ....*....|....*....|....*....
gi 1958645956 1685 FTSKVAHADQQLRDLGKFQVATDALKSRE 1713
Cdd:TIGR02168  505 SEGVKALLKNQSGLSGILGVLSELISVDE 533
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 454-783 1.43e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 60.24  E-value: 1.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  454 HFEEEKRQLASLVADLQSSVSNLSQAKEELqqasQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTL 533
Cdd:pfam12128  598 SEEELRERLDKAEEALQSAREKQAAAEEQL----VQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKAL 673

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  534 QEQEQAAQGLRQQVEQLSSSLKLKEQQ-LEEAAKEQEAARQDHAQQLATIVEAREASVrerDAARQQLETLEKEKDAKLE 612
Cdd:pfam12128  674 AERKDSANERLNSLEAQLKQLDKKHQAwLEEQKEQKREARTEKQAYWQVVEGALDAQL---ALLKAAIAARRSGAKAELK 750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  613 SLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGelhaciEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKV 692
Cdd:pfam12128  751 ALETWYKRDLASLGVDPDVIAKLKREIRTLERKIE------RIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAIS 824

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  693 QLQEQLQALEETLKIVRGSLEEEKcraaDALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLE--ARLQQLEE 770
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMER----KASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGErlAQLEDLKL 900

                          330
                   ....*....|...
gi 1958645956  771 AHQAETEALRHEL 783
Cdd:pfam12128  901 KRDYLSESVKKYV 913
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 391-1071 1.54e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.37  E-value: 1.54e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  391 RAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLEcERGKQEAQLLAERGHFEEEKRQ-LASLVADL 469
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLT-LRSQLLTLCTPCMPDTYHERKQvLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  470 QSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQ 549
Cdd:TIGR00618  232 REALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQR 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  550 LSSSLKLKE---QQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAK------------LESL 614
Cdd:TIGR00618  312 IHTELQSKMrsrAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHtltqhihtlqqqKTTL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  615 QQQLQASNEARDTAQTSVTQAQREKAE---LSQKIGELHACIEAAHQE---QRQAQAHVTELEAQLKAEQQKATEREKVV 688
Cdd:TIGR00618  392 TQKLQSLCKELDILQREQATIDTRTSAfrdLQGQLAHAKKQQELQQRYaelCAAAITCTAQCEKLEKIHLQESAQSLKER 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  689 QEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRH-------ATEMEAETRHLMEQREQEQKELEQEKAERKGL 761
Cdd:TIGR00618  472 EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHpnparqdIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQL 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  762 EARLQQLEEaHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALK-------- 833
Cdd:TIGR00618  552 TSERKQRAS-LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdv 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  834 -GEHGKIGQEEQKEAGEIHGEGQTGQQQSQ---LAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLK 909
Cdd:TIGR00618  631 rLHLQQCSQELALKLTALHALQLTLTQERVrehALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  910 ALVLKAGEQQaaashelkeppragnqesdweEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQ 989
Cdd:TIGR00618  711 THIEEYDREF---------------------NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEE 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  990 EREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKA 1069
Cdd:TIGR00618  770 VTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITH 849


                   ..
gi 1958645956 1070 LQ 1071
Cdd:TIGR00618  850 QL 851
PTZ00121 PTZ00121
MAEBL; Provisional
 1231-1666 2.66e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 2.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1231 LNRQVLEKEGESKELKRLVVAESEKSQKLEE--RLRLLQVETASSSARAAERSSALR--EEVQSLRE--EVEKQRVVSEN 1304
Cdd:PTZ00121  1072 LKPSYKDFDFDAKEDNRADEATEEAFGKAEEakKTETGKAEEARKAEEAKKKAEDARkaEEARKAEDarKAEEARKAEDA 1151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1305 LRQELASQAERAEESGQELKAWQEKffQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREE--IEQS 1382
Cdd:PTZ00121  1152 KRVEIARKAEDARKAEEARKAEDAK--KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAkkAEAV 1229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1383 KQA--AGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaEENRGLGE--RANLGRQF 1458
Cdd:PTZ00121  1230 KKAeeAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKA-----EEKKKADEakKAEEKKKA 1304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1459 LEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFH 1538
Cdd:PTZ00121  1305 DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAK 1384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1539 R--EQTKQVEELNKKLTE----SEQASRVQQQKLKAFQA-QGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKA 1611
Cdd:PTZ00121  1385 KkaEEKKKADEAKKKAEEdkkkADELKKAAAAKKKADEAkKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956 1612 KTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLgRELQQAGLKTKEAEQA 1666
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA-KKAAEAKKKADEAKKA 1518
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 300-918 2.76e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 59.47  E-value: 2.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  300 LKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSE 379
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  380 ILQEKISQLED-----RAAQLQGSPA--------PEKGEVLGDALQLDTLKQEAAKLATD---NTELQARVETLECERGK 443
Cdd:pfam12128  326 ALEDQHGAFLDadietAAADQEQLPSwqselenlEERLKALTGKHQDVTAKYNRRRSKIKeqnNRDIAGIKDKLAKIREA 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  444 QEAQLLAERGHFE------------------EEKRQLASLVADLQSSVsNLSQAKEELQQASQAQGAQLTAQLASLTALN 505
Cdd:pfam12128  406 RDRQLAVAEDDLQaleselreqleagklefnEEEYRLKSRLGELKLRL-NQATATPELLLQLENFDERIERAREEQEAAN 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  506 A---TLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQ--------VEQLSSSLKLKEQQLEEAAKEQEAARQD 574
Cdd:pfam12128  485 AeveRLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtlLHFLRKEAPDWEQSIGKVISPELLHRTD 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  575 HAQQLATIVEAREASVRERDAARQQLETleKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIE 654
Cdd:pfam12128  565 LDPEVWDGSVGGELNLYGVKLDLKRIDV--PEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREET 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  655 AAHQEQRQAQAHVTELEAQLKAEQ---QKATEREK--VVQEKVQLQEQLQALEETLKivrgsleeekcraaDALKEQQRH 729
Cdd:pfam12128  643 FARTALKNARLDLRRLFDEKQSEKdkkNKALAERKdsANERLNSLEAQLKQLDKKHQ--------------AWLEEQKEQ 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  730 ATEmeaetrHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAE---SEREQLLREVES 806
Cdd:pfam12128  709 KRE------ARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPdviAKLKREIRTLER 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  807 WQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIhgEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQK 886
Cdd:pfam12128  783 KIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISEL--QQQLARLIADTKLRRAKLEMERKASEKQQVRLSE 860

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1958645956  887 LLDDLSALREKMA-----ATNKEVACLKALVLKAGEQ 918
Cdd:pfam12128  861 NLRGLRCEMSKLAtlkedANSEQAQGSIGERLAQLED 897
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 354-703 3.16e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 59.20  E-value: 3.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  354 AEKQAHLESelstALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGevLGDALQLD----TLKQEAAKLATDNTE 429
Cdd:COG3096    278 NERRELSER----ALELRRELFGARRQLAEEQYRLVEMARELEELSARESD--LEQDYQAAsdhlNLVQTALRQQEKIER 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  430 LQARVETLE----------CERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLS----------QAKEELQQASQA 489
Cdd:COG3096    352 YQEDLEELTerleeqeevvEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQtraiqyqqavQALEKARALCGL 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  490 QGAQLTAQLASLTALNATLQQQDQELTSLKEQ------AKKEQAQMLQTLQ------EQEQAAQGLRQQVEQLSSsLKLK 557
Cdd:COG3096    432 PDLTPENAEDYLAAFRAKEQQATEEVLELEQKlsvadaARRQFEKAYELVCkiagevERSQAWQTARELLRRYRS-QQAL 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  558 EQQLEEAAKEQEAARQDHAQQLATIVEAREASVR--ERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQA 635
Cdd:COG3096    511 AQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRigQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQL 590

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956  636 QREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEE 703
Cdd:COG3096    591 RARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALES 658
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
412-617 7.26e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 7.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  412 QLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLaerghfEEEKRQLASLVADLQSSVSNLSQAKEELQqasqaqg 491
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELL------EAELEELRAELARLEAELERLEARLDALR------- 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  492 aqltaqlASLTALNATLQQQDQELtslKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAA 571
Cdd:COG4913    323 -------EELDELEAQIRGNGGDR---LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAL 392

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1958645956  572 RQDHAQQLATIVEAREASVRERDAARQQLETLEKEkdakLESLQQQ 617
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDLRRELRELEAE----IASLERR 434
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1152-1664 9.01e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.42  E-value: 9.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1152 AEQDKALETLQGQLEEKARELGHNQAASASAQREL--QALRAKAQDHSKAEEEWKaQVARGQQEAERKsslISSLEEEVS 1229
Cdd:pfam05483  168 AEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELrvQAENARLEMHFKLKEDHE-KIQHLEEEYKKE---INDKEKQVS 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1230 ILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQEL 1309
Cdd:pfam05483  244 LLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIAT 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1310 ASQAERAEESgqelKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhlcqqlqaeqaaaekrfREEIEQSKQAAGGL 1389
Cdd:pfam05483  324 KTICQLTEEK----EAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE-----------------QQRLEKNEDQLKII 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1390 QAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLGERAnlgrqfleVELDQAREK 1469
Cdd:pfam05483  383 TMELQKKSSELEEMTKFKNNKEVELEELKKILAED----EKLLDEKKQFEKIAEELKGKEQEL--------IFLLQAREK 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1470 YVQELaavrtdaETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLE----------ERQRFQEERQKLTAQVEQLEVFHR 1539
Cdd:pfam05483  451 EIHDL-------EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEltahcdklllENKELTQEASDMTLELKKHQEDII 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1540 EQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQClqtqlselqaQLSQKEQAAEHYKLQMEKAKTHYDAKK 1619
Cdd:pfam05483  524 NCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKC----------KLDKSEENARSIEYEVLKKEKQMKILE 593

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1958645956 1620 QQNQELREQLQD----LEQLQKDNKELRSETERLGRELQQAGLKTKEAE 1664
Cdd:pfam05483  594 NKCNNLKKQIENknknIEELHQENKALKKKGSAENKQLNAYEIKVNKLE 642
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 463-681 1.03e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  463 ASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQG 542
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  543 LRQQVEQLSSSLKlKEQQLEEAAKEQEAARQDHAQQ-------LATIVEAREASVRERDAARQQLETLEKEKDAKLESLQ 615
Cdd:COG4942     99 LEAQKEELAELLR-ALYRLGRQPPLALLLSPEDFLDavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956  616 QQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKA 681
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
458-1007 1.09e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  458 EKRQLASLVADLQSSVSNLSQAKEELQQASQAQgaqltAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQT-LQEQ 536
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDAREQI-----ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRrLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  537 EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQ 616
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGL 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  617 QLQASneaRDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKA-EQQKATEREKVVQEKVQLQ 695
Cdd:COG4913    374 PLPAS---AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASlERRKSNIPARLLALRDALA 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  696 EQLQALEETLKIV-------------RGSLE------------EEKCRAA-----DALKEQQRHATEmEAETRHLMEQRE 745
Cdd:COG4913    451 EALGLDEAELPFVgelievrpeeerwRGAIErvlggfaltllvPPEHYAAalrwvNRLHLRGRLVYE-RVRTGLPDPERP 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  746 QEQKELEQEKAERKG------LEARLQQLEEAHQAET-EALRHELAGATAAQHGAESEReqllreveSWQKRVEARQQEE 818
Cdd:COG4913    530 RLDPDSLAGKLDFKPhpfrawLEAELGRRFDYVCVDSpEELRRHPRAITRAGQVKGNGT--------RHEKDDRRRIRSR 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  819 ARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHG-EGQTGQQQSQLAQLHAC---------LAKALQQVQEKEARAQKLL 888
Cdd:COG4913    602 YVLGFDNRAKLAALEAELAELEEELAEAEERLEAlEAELDALQERREALQRLaeyswdeidVASAEREIAELEAELERLD 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  889 ---DDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKeppragnqesDWEEEQARplgSTQAALKAVQREAEQMG 965
Cdd:COG4913    682 assDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE----------QAEEELDE---LQDRLEAAEDLARLELR 748

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1958645956  966 GELERLRAALMQSQgQQQEVRGQQEREVARLTQERGQAQADL 1007
Cdd:COG4913    749 ALLEERFAAALGDA-VERELRENLEERIDALRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
343-820 1.21e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  343 IEEHSKASQEWAEKQAHLESELSTAlqDKKCLEEKSEILQEKISQLEDRAAQLQGspapekgevlgdalQLDTLKQEAAK 422
Cdd:COG4913    257 IRELAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEA--------------ELERLEARLDA 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  423 LATDNTELQARVETLEcerGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLT 502
Cdd:COG4913    321 LREELDELEAQIRGNG---GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  503 ALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAA----QGLRQQVEQLSSSLKLKEQQLE------EAAKEQEAAR 572
Cdd:COG4913    398 EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAELPfvgeliEVRPEEERWR 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  573 -----------------QDHAQQLATIVEAREAS-------VRERDAARQQLETLEKEKDAKLES--------LQQQLQ- 619
Cdd:COG4913    478 gaiervlggfaltllvpPEHYAAALRWVNRLHLRgrlvyerVRTGLPDPERPRLDPDSLAGKLDFkphpfrawLEAELGr 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  620 -------ASNEARDTAQTSVTQ----------------------------AQREKAELSQKIGELHACIEAAHQEQRQAQ 664
Cdd:COG4913    558 rfdyvcvDSPEELRRHPRAITRagqvkgngtrhekddrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALE 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  665 AHVTELEAQLKAEQQKATEREKVVqEKVQLQEQLQALEETLKIVRgsleeekcRAADALKEQQRHATEMEAETRHLMEQR 744
Cdd:COG4913    638 AELDALQERREALQRLAEYSWDEI-DVASAEREIAELEAELERLD--------ASSDDLAALEEQLEELEAELEELEEEL 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956  745 EQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEAR 820
Cdd:COG4913    709 DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNR 784
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1199-1598 1.57e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 1.57e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1199 AEEEWKAQVARGQ-QEAERKSSLISSLEEEVsilnRQVLEKEGESKElkrlvvaESEKSQKLEERLRLLQVETASSSARA 1277
Cdd:TIGR02169  166 AEFDRKKEKALEElEEVEENIERLDLIIDEK----RQQLERLRRERE-------KAERYQALLKEKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1278 AERS-SALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEkffqkeqalsalqlehtstqalvsellp 1356
Cdd:TIGR02169  235 LERQkEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---------------------------- 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1357 akhlcqqlqaeqaaaekrfrEEIEQSKQAAGGLQAELMRAQRelgelgSLRQKIVEQERAAQQLRAEKASYAEQLSMLKK 1436
Cdd:TIGR02169  287 --------------------EEQLRVKEKIGELEAEIASLER------SIAEKERELEDAEERLAKLEAEIDKLLAEIEE 340

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1437 AHGLLAEENRglgERANLGRQFleVELDQAREKYVQELAAVRTDAethlAEMRQEAQSTSRELEVMTAKYESAKV---KV 1513
Cdd:TIGR02169  341 LEREIEEERK---RRDKLTEEY--AELKEELEDLRAELEEVDKEF----AETRDELKDYREKLEKLKREINELKReldRL 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1514 LEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQ 1593
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491


                   ....*
gi 1958645956 1594 LSQKE 1598
Cdd:TIGR02169  492 LAEAE 496
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 512-1337 1.62e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 1.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  512 DQELTSLKEQAKKEQAQmLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQlATIVEAREASVR 591
Cdd:pfam02463  159 EEEAAGSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-YLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  592 ERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELhacIEAAHQEQRQAQAHVTELE 671
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE---EEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  672 AQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKEL 751
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  752 EQEKA----------------ERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAE------------SEREQLLRE 803
Cdd:pfam02463  394 EEELElkseeekeaqlllelaRQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEElekqelkllkdeLELKKSEDL 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  804 VESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEAR 883
Cdd:pfam02463  474 LKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEV 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  884 AQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQ 963
Cdd:pfam02463  554 SATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  964 MGGELERLRAALMQSQGQQQEVRGQQER-EVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHA 1042
Cdd:pfam02463  634 LTKLKESAKAKESGLRKGVSLEEGLAEKsEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1043 MTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEdasgdgpgsQLHTPGKTEAPGPEVEALRAE 1122
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKE---------EEKSELSLKEKELAEEREKTE 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1123 ISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEE 1202
Cdd:pfam02463  785 KLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEIT 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1203 WKAQVARG------QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSAR 1276
Cdd:pfam02463  865 KEELLQELllkeeeLEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEE 944

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645956 1277 AAERSSA------LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQAL 1337
Cdd:pfam02463  945 ADEKEKEennkeeEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAI 1011
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 498-735 2.01e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  498 LASLTALNATLQQQDQeltslKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQ 577
Cdd:COG4942      6 LLALLLALAAAAQADA-----AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  578 QLATIVEAReasvRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAH 657
Cdd:COG4942     81 LEAELAELE----KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR 156

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956  658 QEQRQAQAHVTELEAQLKAEQQKATEREkvvQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEA 735
Cdd:COG4942    157 ADLAELAALRAELEAERAELEALLAELE---EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
586-1005 2.18e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 2.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  586 REASVRERDAARQQLETLEkEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGelhacIEAAHQEQRQAQA 665
Cdd:COG4717     66 PELNLKELKELEEELKEAE-EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ-----LLPLYQELEALEA 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  666 HVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKcraADALKEQQRHATEMEAETRHLMEQRE 745
Cdd:COG4717    140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLAT---EEELQDLAEELEELQQRLAELEEELE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  746 QEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREV-----------------ESWQ 808
Cdd:COG4717    217 EAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIagvlflvlgllallfllLARE 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  809 KRVEARQQEEARYGAMF----QEQLMALKGEHGKIGQEEQKEAGE-IHGEGQTGQQQSQLAQLHACLAKALQQVQEKEAR 883
Cdd:COG4717    297 KASLGKEAEELQALPALeeleEEELEELLAALGLPPDLSPEELLElLDRIEELQELLREAEELEEELQLEELEQEIAALL 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  884 AQKLLDDLSALREKMAATNKEVAcLKALVLKAGEQQAAASHELKEPPRAGNQEsDWEEEqarpLGSTQAALKAVQREAEQ 963
Cdd:COG4717    377 AEAGVEDEEELRAALEQAEEYQE-LKEELEELEEQLEELLGELEELLEALDEE-ELEEE----LEELEEELEELEEELEE 450

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1958645956  964 MGGELERLRAAL--MQSQGQQQEVRGQQEREVARLTQERGQAQA 1005
Cdd:COG4717    451 LREELAELEAELeqLEEDGELAELLQELEELKAELRELAEEWAA 494
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1116-1623 2.40e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 2.40e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1116 VEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELghnqaasASAQRELQALRAKAQD 1195
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL-------EELEAELEELREELEK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1196 HSKAEEEWKAQVARGQQEAErksslISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSA 1275
Cdd:COG4717    121 LEKLLQLLPLYQELEALEAE-----LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1276 RAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQA-LSALQLEHTSTQALVSEL 1354
Cdd:COG4717    196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTI 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1355 LPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAelmraqrelgelgslrQKIVEQERAAQQLRAEKASYAEQLSML 1434
Cdd:COG4717    276 AGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPA----------------LEELEEEELEELLAALGLPPDLSPEEL 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1435 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVL 1514
Cdd:COG4717    340 LELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELE 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1515 EERQRFQEERqkLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQqqklkafqaqggESQQEVQCLQTQLSELQAQL 1594
Cdd:COG4717    420 ELLEALDEEE--LEEELEELEEELEELEEELEELREELAELEAELEQL------------EEDGELAELLQELEELKAEL 485

                          490       500
                   ....*....|....*....|....*....
gi 1958645956 1595 SQKEQAAEHYKLQMEKAKTHYDAKKQQNQ 1623
Cdd:COG4717    486 RELAEEWAALKLALELLEEAREEYREERL 514
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1239-1679 3.84e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 3.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1239 EGESKEL-KRLVVAESEKSQKLEERLRL-LQVETASSSARAA----ERSSALREEVQSLREEVEKQRVV-------SENL 1305
Cdd:PRK02224   198 EKEEKDLhERLNGLESELAELDEEIERYeEQREQARETRDEAdevlEEHEERREELETLEAEIEDLRETiaetereREEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1306 RQELASQAERAEESGQELkawqekffqkEQALSALQLEHTSTQAL---VSELLPAKHLCQQLQAEQAAAEKRFREEIEQS 1382
Cdd:PRK02224   278 AEEVRDLRERLEELEEER----------DDLLAEAGLDDADAEAVearREELEDRDEELRDRLEECRVAAQAHNEEAESL 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1383 KQAAGGLQAELMRAQRELGELGSlrqKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERanlgRQFLEVE 1462
Cdd:PRK02224   348 REDADDLEERAEELREEAAELES---ELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDF----LEELREE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1463 LDQAREKyVQELAAVRTDAETHLAEMRQ-----EAQSTSRELEvmtakyESAKVKVLEERQrfqEERQKLTAQVEQLEVF 1537
Cdd:PRK02224   421 RDELRER-EAELEATLRTARERVEEAEAlleagKCPECGQPVE------GSPHVETIEEDR---ERVEELEAELEDLEEE 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1538 HREQTKQVEELnKKLTESE-QASRVQQQ-----KLKAFQAQGGESQQE-VQCLQTQLSELQAQLSQKEQAAEHYKLQMEK 1610
Cdd:PRK02224   491 VEEVEERLERA-EDLVEAEdRIERLEERredleELIAERRETIEEKRErAEELRERAAELEAEAEEKREAAAEAEEEAEE 569

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958645956 1611 AKTH---YDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEA 1679
Cdd:PRK02224   570 AREEvaeLNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEA 641
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1115-1540 4.70e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.05  E-value: 4.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:PRK02224   273 EREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDAD 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILnrqvlekEGESKELKRLVVAESEKSQKLEERLRLLqvetASSS 1274
Cdd:PRK02224   353 DLEERAEELREEAAELESELEEAREAVEDRREEIEEL-------EEEIEELRERFGDAPVDLGNAEDFLEEL----REER 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLR-----QEL--ASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTST 1347
Cdd:PRK02224   422 DELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVegSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1348 QALV------SELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAEL-----------MRAQRELGELGSLRQKI 1410
Cdd:PRK02224   502 EDLVeaedriERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAeekreaaaeaeEEAEEAREEVAELNSKL 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1411 VEQERAAQQLR------AEKASYAEQLSMLKKAHGLLAEENR----GLGERANLGRQfLEVELDQARekyVQELAAVRTD 1480
Cdd:PRK02224   582 AELKERIESLErirtllAAIADAEDEIERLREKREALAELNDerreRLAEKRERKRE-LEAEFDEAR---IEEAREDKER 657

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1481 AETHLAEMRQEAQSTSRELEVMTAKYESAKVKvLEERQRFQEERQKLTAQVEQLEVFHRE 1540
Cdd:PRK02224   658 AEEYLEQVEEKLDELREERDDLQAEIGAVENE-LEELEELRERREALENRVEALEALYDE 716
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 310-1028 6.29e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.97  E-value: 6.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  310 KISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLE 389
Cdd:TIGR00618  177 QYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  390 DRAAQLQGSPApekgevlgdalQLDTLKQEAAKLATDNTELqarvetlecERGKQEAQLLAERGHFEEEKRQLASLVADL 469
Cdd:TIGR00618  257 KKQQLLKQLRA-----------RIEELRAQEAVLEETQERI---------NRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  470 QSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNAT--LQQQDQELTSLKEQAKKEQA--QMLQTLQEQEQAAqglrQ 545
Cdd:TIGR00618  317 QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEihIRDAHEVATSIREISCQQHTltQHIHTLQQQKTTL----T 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  546 QVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEAr 625
Cdd:TIGR00618  393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKER- 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  626 dtaqtsvTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETL 705
Cdd:TIGR00618  472 -------EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSE 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  706 KIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQ---QLEEAHQAETEALRHE 782
Cdd:TIGR00618  545 EDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEaedMLACEQHALLRKLQPE 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  783 LAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQT-GQQQS 861
Cdd:TIGR00618  625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMlAQCQT 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  862 QLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAgeqQAAASHELKEPPRAGNQESDWEE 941
Cdd:TIGR00618  705 LLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKA---RTEAHFNNNEEVTAALQTGAELS 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  942 EQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRL 1021
Cdd:TIGR00618  782 HLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQL 861


                   ....*..
gi 1958645956 1022 QNTLNEQ 1028
Cdd:TIGR00618  862 AQLTQEQ 868
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 214-483 9.73e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 9.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  214 MRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRidhlalLNEKQAASPQEpseLEELRGKNESLTVRLHET 293
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ------LEQEEEKLKER---LEELEEDLSSLEQEIENV 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  294 LKQCQNLKTEKNQMDRKISQLSEENGDLsfKVREFANHLQQLQGAFNDLIEEHSkasqEWAEKQAHLESELSTALQDKKC 373
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVS----RIEARLREIEQKLNRLTLEKEY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  374 LEEKSEILQEKISQLEDRAAQLQGspapekgevlgdalQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERG 453
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEK--------------EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270
                   ....*....|....*....|....*....|
gi 1958645956  454 HFEEEKRQLASLVADLQSSVSNLSQAKEEL 483
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKL 926
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1241-1679 1.12e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.00  E-value: 1.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1241 ESKELKRLVVAESEKSQKLEERLRLLQvETASSSARAAERSSALREEVQSLREEVEKQRVVSE--NLRQELASQAERAEE 1318
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLPLYQEleALEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1319 SGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQR 1398
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1399 ELGELGSLRQKIVEQERAaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVR 1478
Cdd:COG4717    228 ELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1479 TDAETHLAEMRQEA-QSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQvEELNKKLTESEQ 1557
Cdd:COG4717    307 LQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA-ALLAEAGVEDEE 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1558 ASRVQQQKLKAFQAqggesqqevqcLQTQLSELQAQLSQKEQAAEHYkLQMEKAKTHYDAKKQQNQELREQLQDLEQLQK 1637
Cdd:COG4717    386 ELRAALEQAEEYQE-----------LKEELEELEEQLEELLGELEEL-LEALDEEELEEELEELEEELEELEEELEELRE 453

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1958645956 1638 DNKELRSETERL--GRELQQAGLKTKEAEQACRHLTAQVRSLEA 1679
Cdd:COG4717    454 ELAELEAELEQLeeDGELAELLQELEELKAELRELAEEWAALKL 497
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1187-1310 1.40e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 53.32  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1187 QALRaKAQDHSKAEEEWKAQVARGQQEAERkssliSSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL 1266
Cdd:COG2433    380 EALE-ELIEKELPEEEPEAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEA 453

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1958645956 1267 QVEtASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELA 1310
Cdd:COG2433    454 RSE-ERREIRKDREISRLDREIERLERELEEERERIEELKRKLE 496
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 274-727 1.54e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  274 SELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQgafnDLIEEHSKASQEW 353
Cdd:TIGR04523  145 TEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLK----KKIQKNKSLESQI 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  354 AEkqahLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQAR 433
Cdd:TIGR04523  221 SE----LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSE 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  434 VETLECErgKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQasqaqgaqLTAQLASLTALNATLQQQDQ 513
Cdd:TIGR04523  297 ISDLNNQ--KEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ--------LKKELTNSESENSEKQRELE 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  514 ELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVE--------- 584
Cdd:TIGR04523  367 EKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKnnseikdlt 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  585 ----AREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQ 660
Cdd:TIGR04523  447 nqdsVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKI 526

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958645956  661 RQAQAHVTELEAQLKAEQQKATE------REKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQ 727
Cdd:TIGR04523  527 EKLESEKKEKESKISDLEDELNKddfelkKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKK 599
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1115-1649 1.81e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEqdkaLETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE----LETLEAEIEDLRETIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERlrllqvetassS 1274
Cdd:PRK02224   290 ELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEER-----------A 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1355 lpAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGglqaelmraqrelgeLGSLRQKIVEQERAAQQLRAEKASYAEQLSML 1434
Cdd:PRK02224   439 --RERVEEAEALLEAGKCPECGQPVEGSPHVET---------------IEEDRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1435 KKAHGLLAEENRgLGERANLGRQFLEVELDQAREKYVQeLAAVRTDAETHLAEMR------QEAQSTSRELEVMTAKYES 1508
Cdd:PRK02224   502 EDLVEAEDRIER-LEERREDLEELIAERRETIEEKRER-AEELRERAAELEAEAEekreaaAEAEEEAEEAREEVAELNS 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1509 AKVKVLEERQRF------QEERQKLTAQVEQLevfhREQTKQVEELNKKLTESEQASRVQQQKLKAfqAQGGESQQEVQC 1582
Cdd:PRK02224   580 KLAELKERIESLerirtlLAAIADAEDEIERL----REKREALAELNDERRERLAEKRERKRELEA--EFDEARIEEARE 653

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645956 1583 LQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERL 1649
Cdd:PRK02224   654 DKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEALEALYDEAEEL 720
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1209-1602 1.88e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.42  E-value: 1.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1209 RGQQEAERKSSLISSLEEEVSILNRQVLEKEGE----SKELKRLVVAESEKSQKLE---ERLRLLQvetasSSARAAERS 1281
Cdd:COG3096    275 RHANERRELSERALELRRELFGARRQLAEEQYRlvemARELEELSARESDLEQDYQaasDHLNLVQ-----TALRQQEKI 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1282 SALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLC 1361
Cdd:COG3096    350 ERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALC 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1362 QQLQAEQAAAEKR---FREEIEQSKQAAGGLQAELMRAQ---RELGELGSLRQKI---VEQERAAQQLRAEKASYAEQLS 1432
Cdd:COG3096    430 GLPDLTPENAEDYlaaFRAKEQQATEEVLELEQKLSVADaarRQFEKAYELVCKIageVERSQAWQTARELLRRYRSQQA 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1433 MLKKAHGL---LAEENRGLGERANLGRQFleveldqarEKYVQELAAVRTDAEThLAEMRQEAQSTSRELEvmtakyesa 1509
Cdd:COG3096    510 LAQRLQQLraqLAELEQRLRQQQNAERLL---------EEFCQRIGQQLDAAEE-LEELLAELEAQLEELE--------- 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1510 kvkvlEERQRFQEERQKLtaqveqlevfhREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGE----SQQEVQCLQT 1585
Cdd:COG3096    571 -----EQAAEAVEQRSEL-----------RQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEaladSQEVTAAMQQ 634

                          410
                   ....*....|....*..
gi 1958645956 1586 QLSELQAQLSQKEQAAE 1602
Cdd:COG3096    635 LLEREREATVERDELAA 651
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
990-1634 1.91e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 1.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  990 EREVARLTQERGQAQA-DLAQEKAAKAELEMRLQNTLNEQRvEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELK 1068
Cdd:COG4913    248 REQIELLEPIRELAERyAAARERLAELEYLRAALRLWFAQR-RLELLEAELEELRAELARLEAELERLEARLDALREELD 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1069 ALQQTLEelkkkekehptggargedasgdgpgsqlhtpgktEAPGPEVEALRAEISKLERQWQQQQQQveglthsleser 1148
Cdd:COG4913    327 ELEAQIR----------------------------------GNGGDRLEQLEREIERLERELEERERR------------ 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1149 acRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDhskAEEEWKAQVARGQQEAERKSSLISSLEEEV 1228
Cdd:COG4913    361 --RARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRELEAEIASLERRK 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1229 SILNRQVLekegeskELKRLVVAESEKSqklEERLR----LLQVETASSSAR-AAERssALREEVQSL--REEVEKQ--R 1299
Cdd:COG4913    436 SNIPARLL-------ALRDALAEALGLD---EAELPfvgeLIEVRPEEERWRgAIER--VLGGFALTLlvPPEHYAAalR 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1300 VV-SENLRQELASQAERAEESGQELKAwqekfFQKEQALSALQLEHTSTQALVSELL--PAKHLCQqlqaeqaaaekrfr 1376
Cdd:COG4913    504 WVnRLHLRGRLVYERVRTGLPDPERPR-----LDPDSLAGKLDFKPHPFRAWLEAELgrRFDYVCV-------------- 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1377 EEIEQSKQAAGGLQAE-LMRAQRELGELG-------------SLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLA 1442
Cdd:COG4913    565 DSPEELRRHPRAITRAgQVKGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQ 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1443 EENRGLGERANLgrQFLEVELDQAREKYVQelaavrtdaethLAEMRQEAQSTSRELEVMTAKYESAKvkvlEERQRFQE 1522
Cdd:COG4913    645 ERREALQRLAEY--SWDEIDVASAEREIAE------------LEAELERLDASSDDLAALEEQLEELE----AELEELEE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1523 ERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKL--KAFQAQGGE--SQQEVQCLQTQLSELQAQLSQKE 1598
Cdd:COG4913    707 ELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleERFAAALGDavERELRENLEERIDALRARLNRAE 786

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 1958645956 1599 QAAE----HYKLQMEKAKTHYDAKKQQNQELREQLQDLEQ 1634
Cdd:COG4913    787 EELEramrAFNREWPAETADLDADLESLPEYLALLDRLEE 826
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
416-636 1.94e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 1.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  416 LKQEAAKLATDNTELQARVETLecergKQEAQLLAerghFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLT 495
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEF-----RQKNGLVD----LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  496 AQLASLTAL--NATLQQQDQELtslkEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQ 573
Cdd:COG3206    251 SGPDALPELlqSPVIQQLRAQL----AELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQ 326

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958645956  574 DHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQ 636
Cdd:COG3206    327 AREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 274-709 1.99e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 1.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  274 SELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGD----LSFKVREFANHLQQLQGAFNDLIEEHSKA 349
Cdd:TIGR04523  218 SQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQKELEQNNKKIKELEKQLNQLKSEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  350 SQEWAEKQAHLESELSTAL--QDKKCLEEKSEILQ--EKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLAT 425
Cdd:TIGR04523  298 SDLNNQKEQDWNKELKSELknQEKKLEEIQNQISQnnKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  426 DNTELQARVETLECERGKQEAQLLaergHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQ---LTAQLASL- 501
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQ----NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEikdLTNQDSVKe 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  502 ---TALNATLQQQDQELTSLKEQAKKEQAQMLQTLQE---QEQAAQGLRQQVEQLS----------SSLKLKEQQLEEAA 565
Cdd:TIGR04523  454 liiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKElksKEKELKKLNEEKKELEekvkdltkkiSSLKEKIEKLESEK 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  566 KEQEAARQDHAQQLATIveareasvrERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQK 645
Cdd:TIGR04523  534 KEKESKISDLEDELNKD---------DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKE 604

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645956  646 IGELHACIEAAHQEQRQAQAHVTELEAQLKaeqqkatereKVVQEKVQLQEQLQALEETLKIVR 709
Cdd:TIGR04523  605 IEEKEKKISSLEKELEKAKKENEKLSSIIK----------NIKSKKNKLKQEVKQIKETIKEIR 658
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 575-1072 2.24e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 2.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  575 HAQQLATIVEAREASVRerDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAElsqKIGELHACIE 654
Cdd:pfam12128  180 HIDKIAKAMHSKEGKFR--DVKSMIVAILEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFT---KLQQEFNTLE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  655 AAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKV-----QLQEQLQALEETLKIVRGSLEeeKCRAA-DALKEQQR 728
Cdd:pfam12128  255 SAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLrtlddQWKEKRDELNGELSAADAAVA--KDRSElEALEDQHG 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  729 HATEMEAETRHLmeqreqEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATaaqhgaeserEQLLREVESWQ 808
Cdd:pfam12128  333 AFLDADIETAAA------DQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK----------EQNNRDIAGIK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  809 KRVEARQQEEARYGAMFQEQLMALKGEhgkigQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLl 888
Cdd:pfam12128  397 DKLAKIREARDRQLAVAEDDLQALESE-----LREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFD- 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  889 DDLSALREKMAATNKEVACLKALVLKAG-----------------EQQAAASHELKEP--PRAG-------NQESDWEEE 942
Cdd:pfam12128  471 ERIERAREEQEAANAEVERLQSELRQARkrrdqasealrqasrrlEERQSALDELELQlfPQAGtllhflrKEAPDWEQS 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  943 QAR-------------------------PLGSTQAALKAVQR-EAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARL 996
Cdd:pfam12128  551 IGKvispellhrtdldpevwdgsvggelNLYGVKLDLKRIDVpEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQA 630

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956  997 TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALThamTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:pfam12128  631 NGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALA---ERKDSANERLNSLEAQLKQLDKKHQAWLE 703
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 931-1680 3.04e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 52.65  E-value: 3.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  931 RAGNQESDWEEEQaRPLGSTQAALKAVQREAEQMGGELERLRA---------ALMQSQGQQQEVRGQQEREVARLTQERG 1001
Cdd:COG3096    286 RALELRRELFGAR-RQLAEEQYRLVEMARELEELSARESDLEQdyqaasdhlNLVQTALRQQEKIERYQEDLEELTERLE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1002 QAQADLAQEKAAKAELEMRLQNT---LNEQRVEFAALQEALTHAMT------------------------EKEGKDQELA 1054
Cdd:COG3096    365 EQEEVVEEAAEQLAEAEARLEAAeeeVDSLKSQLADYQQALDVQQTraiqyqqavqalekaralcglpdlTPENAEDYLA 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1055 KLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKT--------EAPGPEVEALRAEISKL 1126
Cdd:COG3096    445 AFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWQTAREllrryrsqQALAQRLQQLRAQLAEL 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1127 ERQWQQQQQQV---EGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEW 1203
Cdd:COG3096    525 EQRLRQQQNAErllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAW 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1204 -KAQVARGQQEAERKSSLISSleEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERL---------RLLQV----- 1268
Cdd:COG3096    605 lAAQDALERLREQSGEALADS--QEVTAAMQQLLEREREATVERDELAARKQALESQIERLsqpggaedpRLLALaerlg 682

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1269 --------------ETASSSARAAERSSAL--------REEVQSL-----------------------REEVEKQRVVSE 1303
Cdd:COG3096    683 gvllseiyddvtleDAPYFSALYGPARHAIvvpdlsavKEQLAGLedcpedlyliegdpdsfddsvfdAEELEDAVVVKL 762

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1304 NLRQ-------EL-----ASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpAKHLCQQlqaeqaaa 1371
Cdd:COG3096    763 SDRQwrysrfpEVplfgrAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFV-----GGHLAVA-------- 829

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1372 ekrFREEIEQSKQAaggLQAELMRAQRELgelgslrqkiVEQERAAQQLRAEKASYAEQLSMLKKAHG---LLAEEnrGL 1448
Cdd:COG3096    830 ---FAPDPEAELAA---LRQRRSELEREL----------AQHRAQEQQLRQQLDQLKEQLQLLNKLLPqanLLADE--TL 891

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1449 GERanlgRQFLEVELDQARE--KYVQELAAVRTDAETHLAEMRQEAQStsreLEVMTAKYESAKvkvleerqrfqEERQK 1526
Cdd:COG3096    892 ADR----LEELREELDAAQEaqAFIQQHGKALAQLEPLVAVLQSDPEQ----FEQLQADYLQAK-----------EQQRR 952

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1527 LTAQVEQL-EVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQkeqaaehyk 1605
Cdd:COG3096    953 LKQQIFALsEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLAS--------- 1023

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956 1606 lqmekAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERlgRELQQAGLKTKeaeQACRHLTAQVRSLEAQ 1680
Cdd:COG3096   1024 -----LKSSRDAKQQTLQELEQELEELGVQADAEAEERARIRR--DELHEELSQNR---SRRSQLEKQLTRCEAE 1088
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1385-1611 3.32e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1385 AAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELD 1464
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1465 QAREKYVQELAAVRTDaethLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQ 1544
Cdd:COG4942     90 KEIAELRAELEAQKEE----LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645956 1545 VEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKA 1611
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 367-560 3.35e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  367 ALQDKKCLEEKSEILQEKISQLEDRAAQLQGspapEKGEVLGdalQLDTLKQEAAKLATDNTELQARVETLECERGKQEA 446
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKK----EEKALLK---QLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  447 QLLAERGHFEEEKRQLASLVADLQS-----------SVSNLSQAK------EELQQASQAQGAQLTAQLASLTALNATLQ 509
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRlgrqpplalllSPEDFLDAVrrlqylKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645956  510 QQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQ 560
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 218-1068 3.57e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.28  E-value: 3.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  218 KKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQC 297
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  298 QNLKTEKNQ--------MDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQ 369
Cdd:pfam02463  260 IEKEEEKLAqvlkenkeEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  370 DKKCLEEKSEILQEKISQLEDRAAQLQgspapEKGEVLGDALQLDTLKQEAAKLATDNTELQARVEtlecERGKQEAQLL 449
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQE-----KLEQLEEELLAKKKLESERLSSAAKLKEEELELK----SEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  450 AERghfeeeKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQM 529
Cdd:pfam02463  411 LEL------ARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  530 LQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEARE-----ASVRERDAARQQLETLE 604
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKvaistAVIVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  605 KEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATER 684
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  685 EKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAE--RKGLE 762
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLeaEELLA 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  763 ARLQQLEEAHQAETEALRHELAGATAaqhgAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQE 842
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEE----EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  843 EQKEAGEIHGEGQTGQQQsQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAA 922
Cdd:pfam02463  801 EELRALEEELKEEAELLE-EEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  923 SHELKEPPRAGNQESDWEEEQARPLGSTQ--AALKAVQREAEQMggelERLRAALMQSQGQQQEVRGQQEREVARLTQER 1000
Cdd:pfam02463  880 EEQKLKDELESKEEKEKEEKKELEEESQKlnLLEEKENEIEERI----KEEAEILLKYEEEPEELLLEEADEKEKEENNK 955

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956 1001 GQAQADLAQEKAAKAELEmrlqNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELK 1068
Cdd:pfam02463  956 EEEEERNKRLLLAKEELG----KVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1450-1656 3.96e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.94  E-value: 3.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1450 ERANLGRQFLEVELDQAREKYVQ-ELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLT 1528
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEaEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1529 AQVEQLEVFhrEQTKQVEELNKKLTEseqasrvQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAehyklqM 1608
Cdd:COG3206    251 SGPDALPEL--LQSPVIQQLRAQLAE-------LEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI------L 315

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1958645956 1609 EKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQA 1656
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVA 363
46 PHA02562
endonuclease subunit; Provisional
 306-536 4.33e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 51.94  E-value: 4.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  306 QMDR----KISQLSEENGDLSFKVrefaNHLQQLQGAFNDLIEE-HSKASQEWAEKQAHLESELSTALQDKKCLEEKSEI 380
Cdd:PHA02562   167 EMDKlnkdKIRELNQQIQTLDMKI----DHIQQQIKTYNKNIEEqRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  381 LQEKISQLEDRAAQLQgspapekgevlgdalqldtlkqeaaKLATDNTELQARVETLecergKQEAQLLAERGH------ 454
Cdd:PHA02562   243 LLNLVMDIEDPSAALN-------------------------KLNTAAAKIKSKIEQF-----QKVIKMYEKGGVcptctq 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  455 -FEEEKRQLASL---VADLQSSVSNLSQAKEELqqasQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMl 530
Cdd:PHA02562   293 qISEGPDRITKIkdkLKELQHSLEKLDTAIDEL----EEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAI- 367


                   ....*.
gi 1958645956  531 QTLQEQ 536
Cdd:PHA02562   368 EELQAE 373
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1215-1656 4.75e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.15  E-value: 4.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1215 ERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREE 1294
Cdd:pfam12128  247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQE---ERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1295 VEkqrVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQA-------LVSELLPAK--------- 1358
Cdd:pfam12128  324 LE---ALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAkynrrrsKIKEQNNRDiagikdkla 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1359 ------------------HLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQL 1420
Cdd:pfam12128  401 kireardrqlavaeddlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQ 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1421 RAEKASYAEQLSMLKKAHGLLAEENRGLGeRANLGRQFLEVELDQAREKYVQE----LAAVRTDA---ETHLAEMRQEAQ 1493
Cdd:pfam12128  481 EAANAEVERLQSELRQARKRRDQASEALR-QASRRLEERQSALDELELQLFPQagtlLHFLRKEApdwEQSIGKVISPEL 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1494 -------------STSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASR 1560
Cdd:pfam12128  560 lhrtdldpevwdgSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASR 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1561 VQQQKLKAFqaqggesQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAkkQQNQELREQLQDLEQLQKDNK 1640
Cdd:pfam12128  640 EETFARTAL-------KNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA--QLKQLDKKHQAWLEEQKEQKR 710

                          490
                   ....*....|....*.
gi 1958645956 1641 ELRSETERLGRELQQA 1656
Cdd:pfam12128  711 EARTEKQAYWQVVEGA 726
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 858-1073 4.91e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 4.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  858 QQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHElkeppragnqes 937
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE------------ 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  938 dwEEEQARPLGSTQAALKAVQREAEQMGgELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAEL 1017
Cdd:COG4942     92 --IAELRAELEAQKEELAELLRALYRLG-RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956 1018 EMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQT 1073
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
457-1039 5.34e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.96  E-value: 5.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  457 EEKRQLASL----VADLQSSVSN-LSQAKEELQQASQAQgaqLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQ 531
Cdd:PRK02224   165 EEYRERASDarlgVERVLSDQRGsLDQLKAQIEEKEEKD---LHERLNGLESELAELDEEIERYEEQREQARETRDEADE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  532 TLQEQEQAAQGLrQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRE-------RDAARQQLETLE 604
Cdd:PRK02224   242 VLEEHEERREEL-ETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEaglddadAEAVEARREELE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  605 KEKDAKLESLQQQ---LQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQK- 680
Cdd:PRK02224   321 DRDEELRDRLEECrvaAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERf 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  681 ---ATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEekcrAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAE 757
Cdd:PRK02224   401 gdaPVDLGNAEDFLEELREERDELREREAELEATLRT----ARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  758 RKGLEARLQQLEEahqaETEALRHELAGATAAQHgAESEREQLLREVESWQKRVEARQQeearygamfqeqlmalkgehg 837
Cdd:PRK02224   477 VEELEAELEDLEE----EVEEVEERLERAEDLVE-AEDRIERLEERREDLEELIAERRE--------------------- 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  838 kiGQEEQKEageihgegqtgqqqsQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLK-------- 909
Cdd:PRK02224   531 --TIEEKRE---------------RAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKeriesler 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  910 -ALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALkavqrEAEQMGGELERLRAALMQSQGQQQEVrgq 988
Cdd:PRK02224   594 iRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKREL-----EAEFDEARIEEAREDKERAEEYLEQV--- 665

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645956  989 qEREVARLTQERGQAQADLAQEKAAKAELEmrlqnTLNEQRVEFAALQEAL 1039
Cdd:PRK02224   666 -EEKLDELREERDDLQAEIGAVENELEELE-----ELRERREALENRVEAL 710
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 803-1555 5.57e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.76  E-value: 5.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  803 EVESWQKRVEARQQEEARygamfqeqlmaLKGEHGKIGQEEQKEAGEIHgegqtgQQQSQLAQLHACLAKALQQVQEKEA 882
Cdd:pfam12128  242 EFTKLQQEFNTLESAELR-----------LSHLHFGYKSDETLIASRQE------ERQETSAELNQLLRTLDDQWKEKRD 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  883 RAQKlldDLSALREKMAATNKEVACLKA---LVLKAGEQQAAAshELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQR 959
Cdd:pfam12128  305 ELNG---ELSAADAAVAKDRSELEALEDqhgAFLDADIETAAA--DQEQLPSWQSELENLEERLKALTGKHQDVTAKYNR 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  960 E----AEQMGGELERLRAALMQS---------------QGQQQEVRGQQEREVARLTQERGQAQADLAQEK----AAKAE 1016
Cdd:pfam12128  380 RrskiKEQNNRDIAGIKDKLAKIreardrqlavaeddlQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnQATAT 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1017 LEMRLQNTLNEQRVEFAalQEALTHAMTEKEGKDQELAKLREQ-----EAAQISELKALQQTLEELKKKEKEHPTGGARG 1091
Cdd:pfam12128  460 PELLLQLENFDERIERA--REEQEAANAEVERLQSELRQARKRrdqasEALRQASRRLEERQSALDELELQLFPQAGTLL 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1092 EDASGDGPG----------------SQLHTPGKTEAPGPEV---------------------EALRAEISKLERqwqqqq 1134
Cdd:pfam12128  538 HFLRKEAPDweqsigkvispellhrTDLDPEVWDGSVGGELnlygvkldlkridvpewaaseEELRERLDKAEE------ 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1135 qqveglthSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEwkaQVARGQQEA 1214
Cdd:pfam12128  612 --------ALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNK---ALAERKDSA 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1215 ERKsslISSLEEEVSILNRQVLEKEGESKELKRlvVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREE 1294
Cdd:pfam12128  681 NER---LNSLEAQLKQLDKKHQAWLEEQKEQKR--EARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW 755

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1295 ---------VEKQRVVS-ENLRQELASQAERAEESGQELKAW----QEKFFQKEQALsALQLEHTSTQalVSELlpakhl 1360
Cdd:pfam12128  756 ykrdlaslgVDPDVIAKlKREIRTLERKIERIAVRRQEVLRYfdwyQETWLQRRPRL-ATQLSNIERA--ISEL------ 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1361 cQQLQAEQAAAEKRFREEIEQSKQAaggLQAELMRAQRELGELGSLRQKI--VEQERAAQQLRAEKASYAEQLSMLKKAH 1438
Cdd:pfam12128  827 -QQQLARLIADTKLRRAKLEMERKA---SEKQQVRLSENLRGLRCEMSKLatLKEDANSEQAQGSIGERLAQLEDLKLKR 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1439 GLLAEE-NRGLGERANLGRQFLEVELDQAREKYVQELAAVrTDAETHLAEMRQEAQSTSRELEVMTAKyesaKVKVLEER 1517
Cdd:pfam12128  903 DYLSESvKKYVEHFKNVIADHSGSGLAETWESLREEDHYQ-NDKGIRLLDYRKLVPYLEQWFDVRVPQ----SIMVLREQ 977

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958645956 1518 QRFQEerQKLTAQVEQLEVFHREQTKQVEELNKKLTES 1555
Cdd:pfam12128  978 VSILG--VDLTEFYDVLADFDRRIASFSRELQREVGEE 1013
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
625-1070 5.91e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 5.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  625 RDTAQTSVTQAQREKAELSQKigELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEET 704
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  705 LKIVRGSLEE---EKCRAADALKEQQRHATEMEAETRHLMEQREQEQkeleqekAERKGLEARLQQLEEAHQAETEALRH 781
Cdd:PRK02224   260 IEDLRETIAEterEREELAEEVRDLRERLEELEEERDDLLAEAGLDD-------ADAEAVEARREELEDRDEELRDRLEE 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  782 ELAGATAAQHGAESEREQLLR-EVESWQKRVEARQQEEArygamfqeqlmalkgehgkigQEEQKEAGEiHGEGQTGQQQ 860
Cdd:PRK02224   333 CRVAAQAHNEEAESLREDADDlEERAEELREEAAELESE---------------------LEEAREAVE-DRREEIEELE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  861 SQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAAS-----HELKEPPRAGNQ 935
Cdd:PRK02224   391 EEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  936 ESDweEEQARPLGSTQAALKAVQREAEQmggELERLRAAlmqsqgQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKA 1015
Cdd:PRK02224   471 EED--RERVEELEAELEDLEEEVEEVEE---RLERAEDL------VEAEDRIERLEERREDLEELIAERRETIEEKRERA 539

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956 1016 ElemRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKAL 1070
Cdd:PRK02224   540 E---ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL 591
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 252-774 6.13e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 51.71  E-value: 6.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  252 MQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS----QLSEENGDLSFKVRE 327
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  328 FANHLQQLQGafndlieEHSKASQEWAEKQAHLESELST--ALQ-DKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKG 404
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAArqKLQlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  405 EVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQllaeRGHFEEEKRQLASLVADLQSSVSNLSQAKEELQ 484
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  485 QASQAQGAQLTAQLASL---TALNATLQQQDQELTS----LKEQAKKEQAQM--------------------LQTLQEQE 537
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAqiseLQEDLESERAARnkaekqrrdlgeelealkteLEDTLDTT 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  538 QAAQGLRQQVEQLSSSLKLK-EQQLEEAAKEQEAARQDHAQQLATIVEAREASVRER---DAARQQLETLEKEKDAKLES 613
Cdd:pfam01576  316 AAQQELRSKREQEVTELKKAlEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKanlEKAKQALESENAELQAELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  614 LQQQLQASNEARDTA-------QTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREK 686
Cdd:pfam01576  396 LQQAKQDSEHKRKKLegqlqelQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  687 VVQE----KVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLE 762
Cdd:pfam01576  476 LLQEetrqKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELE 555

                          570
                   ....*....|..
gi 1958645956  763 ARLQQLEEAHQA 774
Cdd:pfam01576  556 ALTQQLEEKAAA 567
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 685-1041 6.87e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 51.05  E-value: 6.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  685 EKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEAR 764
Cdd:pfam07888   37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  765 LQQLEEAhQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQ 844
Cdd:pfam07888  117 KDALLAQ-RAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  845 KEAGEIhgeGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASH 924
Cdd:pfam07888  196 ELRNSL---AQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQA 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  925 ELK----EPPRAGNQESD----WEEEQARPLGSTQAALKAVQREAEQmggeLERLRAALMQSQGQQQEVRGQQEREVARL 996
Cdd:pfam07888  273 ELHqarlQAAQLTLQLADaslaLREGRARWAQERETLQQSAEADKDR----IEKLSAELQRLEERLQEERMEREKLEVEL 348

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1958645956  997 TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTH 1041
Cdd:pfam07888  349 GREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEY 393
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 605-820 7.72e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  605 KEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATER 684
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  685 EKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRhatemeaETRHLMEQREQEQKELEQEKAERKGLEAR 764
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP-------ARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956  765 LQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEAR 820
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
mukB PRK04863
chromosome partition protein MukB;
1402-1681 7.85e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.50  E-value: 7.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1402 ELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLaeeNRGLGERANLGRQFLEVELDQARE---------KYVQ 1472
Cdd:PRK04863   838 ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSAL---NRLLPRLNLLADETLADRVEEIREqldeaeeakRFVQ 914

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1473 ELAAVRTDAETHLAEMRQEAQstsrELEVMTAKYESAkvkvleerqrfQEERQKLTAQVEQL-EVFHREQTKQVEELNKK 1551
Cdd:PRK04863   915 QHGNALAQLEPIVSVLQSDPE----QFEQLKQDYQQA-----------QQTQRDAKQQAFALtEVVQRRAHFSYEDAAEM 979

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1552 LTESEQASRVQQQKLKAFQAQGGESQQevqclqtQLSELQAQLSQKEQAaehyklqMEKAKTHYDAKKQQNQELREQLQD 1631
Cdd:PRK04863   980 LAKNSDLNEKLRQRLEQAEQERTRARE-------QLRQAQAQLAQYNQV-------LASLKSSYDAKRQMLQELKQELQD 1045

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958645956 1632 LEQLQKDNKE--LRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQA 1681
Cdd:PRK04863  1046 LGVPADSGAEerARARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKL 1097
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
841-1323 9.32e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 9.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  841 QEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQA 920
Cdd:COG4913    261 AERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRL 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  921 AashELKEPPRAGNQEsdwEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQER 1000
Cdd:COG4913    341 E---QLEREIERLERE---LEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAAL 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1001 GQAQADLAQEKAAKAELEMRlQNTLNEqrvEFAALQEALTHAMTEKEGKDQ---ELAKLREQEAA-QISELKAL------ 1070
Cdd:COG4913    415 RDLRRELRELEAEIASLERR-KSNIPA---RLLALRDALAEALGLDEAELPfvgELIEVRPEEERwRGAIERVLggfalt 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1071 -----QQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGK-------TEAPGPEVEALRAEISK------------L 1126
Cdd:COG4913    491 llvppEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPdslagklDFKPHPFRAWLEAELGRrfdyvcvdspeeL 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1127 ERqwQQQQQQVEGLTHSLESERACRAEQD------------KALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG4913    571 RR--HPRAITRAGQVKGNGTRHEKDDRRRirsryvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1195 DHSKAEEEWKAQ--VARGQQEAERKSSLISSLEE---EVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVE 1269
Cdd:COG4913    649 ALQRLAEYSWDEidVASAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE 728

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645956 1270 TASSSARAAERSSALREEVQSLREEV-------EKQRVVSENLRQELASQAERAEESGQEL 1323
Cdd:COG4913    729 LDELQDRLEAAEDLARLELRALLEERfaaalgdAVERELRENLEERIDALRARLNRAEEEL 789
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1184-1665 9.49e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 9.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1184 RELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLvvaeSEKSQKLEERL 1263
Cdd:PRK03918   172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL----KEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1264 RLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVsenlrQELASQAERAEESGQELKAWQEKFFQKEQALSALQLE 1343
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-----KELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1344 HTSTQALVSELLPAKHLCQQLQAEQAAAEKRFR--EEIEQSKQAAGGLQAELMRAQRELG---------ELGSLRQKIVE 1412
Cdd:PRK03918   323 INGIEERIKELEEKEERLEELKKKLKELEKRLEelEERHELYEEAKAKKEELERLKKRLTgltpeklekELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1413 QERAAQQLRAEKASYAEQLSMLKKAhglLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAEThLAEMRQEA 1492
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKA---IEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKE-IEEKERKL 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1493 QSTSRELEVMTAKYE--SAKVKVLEERQRFQEERQKLtaQVEQLEvfhrEQTKQVEELNKKLTESEQASRV---QQQKLK 1567
Cdd:PRK03918   479 RKELRELEKVLKKESelIKLKELAEQLKELEEKLKKY--NLEELE----KKAEEYEKLKEKLIKLKGEIKSlkkELEKLE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1568 AFQAQGGESQQEVQCLQTQLSELQAQLSQK----EQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELR 1643
Cdd:PRK03918   553 ELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAF 632

                          490       500
                   ....*....|....*....|..
gi 1958645956 1644 SETERLGRELQQAGLKTKEAEQ 1665
Cdd:PRK03918   633 EELAETEKRLEELRKELEELEK 654
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
573-803 1.08e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  573 QDHAQQLATIVEAREASVRERDAARQQLETLEKEKDA---KLESLQQQLQASNEARDTAQTS--VTQAQREKAELSQKIG 647
Cdd:COG4913    606 FDNRAKLAALEAELAELEEELAEAEERLEALEAELDAlqeRREALQRLAEYSWDEIDVASAEreIAELEAELERLDASSD 685

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  648 ELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQ 727
Cdd:COG4913    686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER 765

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956  728 RHATEMEAETRHLmeqreqeqkeleqeKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLRE 803
Cdd:COG4913    766 ELRENLEERIDAL--------------RARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEED 827
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1115-1678 1.15e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.74  E-value: 1.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQD--KALETLQGQLEEKARELGHNQAAsasaqrelQALRAK 1192
Cdd:TIGR00618  268 RIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQaqRIHTELQSKMRSRAKLLMKRAAH--------VKQQSS 339

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1193 AQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRqvlekegeSKELKRLVVAESEKSQKLEERLRLLQVETAS 1272
Cdd:TIGR00618  340 IEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQH--------IHTLQQQKTTLTQKLQSLCKELDILQREQAT 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1273 SSARAAERS------SALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQAL--------- 1337
Cdd:TIGR00618  412 IDTRTSAFRdlqgqlAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHlqetrkkav 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1338 -SALQLEHTSTQALV--SELLPAKHLCQQ---------------LQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRE 1399
Cdd:TIGR00618  492 vLARLLELQEEPCPLcgSCIHPNPARQDIdnpgpltrrmqrgeqTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1400 LGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhglLAEENRGLGERAN--LGRQFLEVELDQAREKYVQELAAV 1477
Cdd:TIGR00618  572 FSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDM---LACEQHALLRKLQpeQDLQDVRLHLQQCSQELALKLTAL 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1478 RTDAETHLAEMRQEAQSTSRELEvmtAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQ 1557
Cdd:TIGR00618  649 HALQLTLTQERVREHALSIRVLP---KELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIEN 725

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1558 ASRVQQQKLKAFQAQGGESQQEVQCLQ----TQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLE 1633
Cdd:TIGR00618  726 ASSSLGSDLAAREDALNQSLKELMHQArtvlKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLE 805

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1634 -----QLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLE 1678
Cdd:TIGR00618  806 aeigqEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYE 855
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1209-1652 1.34e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 50.51  E-value: 1.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1209 RGQQEAERKSS-LISSLEEEVSilnrQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSAL--- 1284
Cdd:pfam05557   27 RARIELEKKASaLKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLada 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1285 REEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQlehTSTQALVSELLPAKHLcqql 1364
Cdd:pfam05557  103 REVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLE---KQQSSLAEAEQRIKEL---- 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1365 qaeqaaaeKRFREEIEQSKQAAGGLQAELMRaqrelgelgslrqkIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEE 1444
Cdd:pfam05557  176 --------EFEIQSQEQDSEIVKNSKSELAR--------------IPELEKELERLREHN----KHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1445 NRGLgeRANLGRQfleveldqarEKYVQELAAVRTDAETHLAEMRQ-EAQSTSRELEVMTAKYESAKVKVLEERQR-FQE 1522
Cdd:pfam05557  230 VEDL--KRKLERE----------EKYREEAATLELEKEKLEQELQSwVKLAQDTGLNLRSPEDLSRRIEQLQQREIvLKE 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1523 ERQKLTAQVEQLEVFHRE-------QTKQVEELNKKLTE-SEQASRVQQQKLKAFQAQGG-------------------- 1574
Cdd:pfam05557  298 ENSSLTSSARQLEKARREleqelaqYLKKIEDLNKKLKRhKALVRRLQRRVLLLTKERDGyrailesydkeltmsnyspq 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1575 ------ESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ--ELREQLQDLEQLQKDNKELRSET 1646
Cdd:pfam05557  378 llerieEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESlaDPSYSKEEVDSLRRKLETLELER 457


                   ....*.
gi 1958645956 1647 ERLGRE 1652
Cdd:pfam05557  458 QRLREQ 463
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 595-1063 1.43e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 50.57  E-value: 1.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  595 AARQQLETLEKE-------KDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKiGELHACIEAAHQEQRQAQAHV 667
Cdd:PRK10246   195 SARTELEKLQAQasgvallTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRL-DELQQEASRRQQALQQALAAE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  668 TELEAQLkAEQQKATEREKVVQEKVQLQEQLQALEETlkivRGSLEEEKCR--AADALKEQQRHATEMEAETRhlmeqre 745
Cdd:PRK10246   274 EKAQPQL-AALSLAQPARQLRPHWERIQEQSAALAHT----RQQIEEVNTRlqSTMALRARIRHHAAKQSAEL------- 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  746 qeqkeleqeKAERKGLEARLQQLEEAHQaeteaLRHELAGATAAQHGAESEREQLLRevesWQKRVEARQQeearygamf 825
Cdd:PRK10246   342 ---------QAQQQSLNTWLAEHDRFRQ-----WNNELAGWRAQFSQQTSDREQLRQ----WQQQLTHAEQ--------- 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  826 qeQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQ-----QSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAA 900
Cdd:PRK10246   395 --KLNALPAITLTLTADEVAAALAQHAEQRPLRQrlvalHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  901 TNKEVACLKALV-----LKAGEQQAAASHELKEPPRAGNQESDW-EEEQARPLGSTQAALKAVQREAEQMGGELERLRAA 974
Cdd:PRK10246   473 KTQQLADVKTICeqearIKDLEAQRAQLQAGQPCPLCGSTSHPAvEAYQALEPGVNQSRLDALEKEVKKLGEEGAALRGQ 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  975 LMQSQGQQQevrgQQEREVARLTQErgqAQADLAQEKAAKAELEMRLQntlneqrvefaaLQEALTHAMTEKEGKDQELA 1054
Cdd:PRK10246   553 LDALTKQLQ----RDESEAQSLRQE---EQALTQQWQAVCASLNITLQ------------PQDDIQPWLDAQEEHERQLR 613


                   ....*....
gi 1958645956 1055 KLREQEAAQ 1063
Cdd:PRK10246   614 LLSQRHELQ 622
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 411-733 1.49e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.34  E-value: 1.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  411 LQLDTLKQEAAKLATDNTELQARVETLECERGKQ---------EAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKE 481
Cdd:COG3096    792 AERDELAEQYAKASFDVQKLQRLHQAFSQFVGGHlavafapdpEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKE 871

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  482 ELQQ--------------ASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQakkeqaqmLQTLQEQEQAAQGLRQQV 547
Cdd:COG3096    872 QLQLlnkllpqanlladeTLADRLEELREELDAAQEAQAFIQQHGKALAQLEPL--------VAVLQSDPEQFEQLQADY 943

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  548 EQLSSSLKLKEQQLEEaakeqeaarqdhaqqLATIVEAREASVRErDAARQQLETLEKEkdaklESLQQQLQASNEARDT 627
Cdd:COG3096    944 LQAKEQQRRLKQQIFA---------------LSEVVQRRPHFSYE-DAVGLLGENSDLN-----EKLRARLEQAEEARRE 1002

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  628 AQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQL--KAEQQKATEREKVVQEKVQLQEQLQALEETL 705
Cdd:COG3096   1003 AREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQAdaEAEERARIRRDELHEELSQNRSRRSQLEKQL 1082

                          330       340       350
                   ....*....|....*....|....*....|
gi 1958645956  706 KIVRGSLEE--EKCRAADALKEQQRHATEM 733
Cdd:COG3096   1083 TRCEAEMDSlqKRLRKAERDYKQEREQVVQ 1112
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 826-1022 1.52e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  826 QEQLMALKGEHGKIGQEEQKEAGEIHG-EGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKE 904
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKAlLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  905 VACLKALVLKAGEQQAAA----SHELKEPPRAG---NQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQ 977
Cdd:COG4942    106 LAELLRALYRLGRQPPLAlllsPEDFLDAVRRLqylKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1958645956  978 SQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQ 1022
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
534-714 1.78e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 1.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  534 QEQEQAAQGLRQQVEQLSSSLKLKEQQLEE-----AAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKE-- 606
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEAEAALEEfrqknGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQlg 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  607 ----------KDAKLESLQQQLQASNEARDTAQT-------SVTQAQREKAELSQKI-GELHACIEAAHQEQRQAQAHVT 668
Cdd:COG3206    251 sgpdalpellQSPVIQQLRAQLAELEAELAELSArytpnhpDVIALRAQIAALRAQLqQEAQRILASLEAELEALQAREA 330

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1958645956  669 ELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEE 714
Cdd:COG3206    331 SLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-535 1.93e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.06  E-value: 1.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  213 QMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLALLNEK-QAASPQEPSELEELRGKNESLTVRLH 291
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQlEERIAQLSKELTELEAEIEELEERLE 771

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  292 ETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESelstalqdk 371
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED--------- 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  372 kcLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAE 451
Cdd:TIGR02168  843 --LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  452 RGHFEEEKRQLASLVADLQSSVSNLS--------------QAKEELQQASQAQGAQLTAQLASLTALNAT-------LQQ 510
Cdd:TIGR02168  921 REKLAQLELRLEGLEVRIDNLQERLSeeysltleeaealeNKIEDDEEEARRRLKRLENKIKELGPVNLAaieeyeeLKE 1000

                          330       340
                   ....*....|....*....|....*
gi 1958645956  511 QDQELTSLKEQAKKEQAQMLQTLQE 535
Cdd:TIGR02168 1001 RYDFLTAQKEDLTEAKETLEEAIEE 1025
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
204-726 2.51e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 2.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  204 GDILQTPQFQMRRLKKQLADERNNRDELElelseslklltEKDAQIAMMQQRIDHLAL----LNEKQAASPQEPSELEEL 279
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIK-----------EKEKELEEVLREINEISSelpeLREELEKLEKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  280 RGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREfanhLQQLQG------AFNDLIEEHSKASQEW 353
Cdd:PRK03918   237 KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE----LKELKEkaeeyiKLSEFYEEYLDELREI 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  354 AEKQAHLESELST---ALQDKKCLEEKSEILQEKISQLEDRAAQLQgspapEKGEVLGDALQLDTLKQEAAKLATDNTEL 430
Cdd:PRK03918   313 EKRLSRLEEEINGieeRIKELEEKEERLEELKKKLKELEKRLEELE-----ERHELYEEAKAKKEELERLKKRLTGLTPE 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  431 QARVETLECERGKQEAQLlaERGHFEEEKRQLASLVADLQSSVSNLSQAK---------------EELQQASQAQGAQLT 495
Cdd:PRK03918   388 KLEKELEELEKAKEEIEE--EISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgrelteehrKELLEEYTAELKRIE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  496 AQLASLTALNATLQQQDQELTS-----------------LKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKE 558
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKvlkkeseliklkelaeqLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  559 QQLEEAakeqeaarQDHAQQLATIVEAREASVRERDAARQQLETL----EKEKDAKLESLQQQLQASNEARDtaqtsvtq 634
Cdd:PRK03918   546 KELEKL--------EELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKD-------- 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  635 AQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATERE--KVVQEKVQLQEQLQALEETLKIVRGSL 712
Cdd:PRK03918   610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyeELREEYLELSRELAGLRAELEELEKRR 689

                          570
                   ....*....|....
gi 1958645956  713 EEEKcRAADALKEQ 726
Cdd:PRK03918   690 EEIK-KTLEKLKEE 702
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1144-1340 2.59e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 49.67  E-value: 2.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1144 LESERACRAEQDKA------LETLQGQLEEKARELghnqaasASAQRELQALRAKAQDHSKAeeewkaQVARGQQEAERK 1217
Cdd:PRK10929   119 LEKSRQAQQEQDRAreisdsLSQLPQQQTEARRQL-------NEIERRLQTLGTPNTPLAQA------QLTALQAESAAL 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1218 SSLISSLE-EEVSILNRQvlekegeskELKRLVVAESEK-SQKLEERLRLLQVETASSSARAAE----RSSALREEVQSL 1291
Cdd:PRK10929   186 KALVDELElAQLSANNRQ---------ELARLRSELAKKrSQQLDAYLQALRNQLNSQRQREAEraleSTELLAEQSGDL 256

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1292 REEVEKQRVVSENLRQELASQAERAEE-SGQELKAWQEKfFQKEQALSAL 1340
Cdd:PRK10929   257 PKSIVAQFKINRELSQALNQQAQRMDLiASQQRQAASQT-LQVRQALNTL 305
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1164-1402 3.24e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1164 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1243
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1244 ELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVsenlRQELASQAERAEESGQEL 1323
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD----LAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956 1324 KAWQEKFFQKEQALSALQLEHTSTQALVSEllpakhlcqqlqaeqaaAEKRFREEIEQSKQAAGGLQAELMRAQRELGE 1402
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEK-----------------ELAELAAELAELQQEAEELEALIARLEAEAAA 238
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
412-638 3.66e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  412 QLDTLKQEAAKLATDNTELQARVETLEcergkQEAQLLAERghfeeekRQLASLVADLQSSVSNLSQAKEELQQasqaqg 491
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALE-----AELDALQER-------REALQRLAEYSWDEIDVASAEREIAE------ 672

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  492 aqLTAQLASLTALNATLQQqdqeltslkeqakkeqaqmlqtLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAA 571
Cdd:COG4913    673 --LEAELERLDASSDDLAA----------------------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE 728

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645956  572 RQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQRE 638
Cdd:COG4913    729 LDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
275-803 4.01e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 4.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  275 ELEELRGKNESLT--VRLHETLKQCQNLKTEKNQMDRKIS--QLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKAS 350
Cdd:COG4913    243 ALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALR 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  351 QEWAE-KQAHLES---ELSTALQDKKCLEEKSEILQEKISQLEDRAAQLqGSPAPEkgevlgDALQLDTLKQEAAKLATD 426
Cdd:COG4913    323 EELDElEAQIRGNggdRLEQLEREIERLERELEERERRRARLEALLAAL-GLPLPA------SAEEFAALRAEAAALLEA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  427 NTELQARVETLECERGKQEAQLlaerghfEEEKRQLASLVADLQSSVSNLSQakeelqqasqaqgaqltAQLASLTALNA 506
Cdd:COG4913    396 LEEELEALEEALAEAEAALRDL-------RRELRELEAEIASLERRKSNIPA-----------------RLLALRDALAE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  507 TLQQQDQELTSLKE--QAKKEQA------------QMLQTLQEQEQAAQGLRqQVEQLSSSLKLKEQQLEEAAKEQEAAR 572
Cdd:COG4913    452 ALGLDEAELPFVGEliEVRPEEErwrgaiervlggFALTLLVPPEHYAAALR-WVNRLHLRGRLVYERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  573 qDHAQQLATIVEAREASVRE-------RDAARQQLETLE---------------------KEKD---------------- 608
Cdd:COG4913    531 -LDPDSLAGKLDFKPHPFRAwleaelgRRFDYVCVDSPEelrrhpraitragqvkgngtrHEKDdrrrirsryvlgfdnr 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  609 AKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQ--RQAQAHVTELEAQLKAEQQKATEREK 686
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLDASSDDLAA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  687 VVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAetrhlmeqreqeqKELEQEKAERKGLEARLQ 766
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA-------------AEDLARLELRALLEERFA 756

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1958645956  767 QL--EEAHQAETEALRHELAGATAAQHGAESEREQLLRE 803
Cdd:COG4913    757 AAlgDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 494-1072 5.55e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.63  E-value: 5.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  494 LTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEeaakeqeaarq 573
Cdd:pfam01576   45 LQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLD----------- 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  574 dhaqqlativeareasvrERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACI 653
Cdd:pfam01576  114 ------------------EEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKA 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  654 EAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQ----EKVQLQEQ---LQALEETLKIVRGSLEEEKCRAADALKEQ 726
Cdd:pfam01576  176 KSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRklegESTDLQEQiaeLQAQIAELRAQLAKKEEELQAALARLEEE 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  727 QRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEahqaETEALRHELA---GATAAQHGAESEREQ---- 799
Cdd:pfam01576  256 TAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE----ELEALKTELEdtlDTTAAQQELRSKREQevte 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  800 LLREVESWQKRVEARQQE-EARYGAMFQ------EQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQ------------Q 860
Cdd:pfam01576  332 LKKALEEETRSHEAQLQEmRQKHTQALEelteqlEQAKRNKANLEKAKQALESENAELQAELRTLQQakqdsehkrkklE 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  861 SQLAQLHACLAKALQQVQEKEARAQKLLDD-------LSALREKMAATNKEVACLKALVLKAGE-------QQAAASHEL 926
Cdd:pfam01576  412 GQLQELQARLSESERQRAELAEKLSKLQSElesvsslLNEAEGKNIKLSKDVSSLESQLQDTQEllqeetrQKLNLSTRL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  927 K--EPPRAGNQESDWEEEQA-----RPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVA---RL 996
Cdd:pfam01576  492 RqlEDERNSLQEQLEEEEEAkrnveRQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAaydKL 571

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956  997 TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:pfam01576  572 EKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEE 647
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 525-705 5.79e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.84  E-value: 5.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  525 EQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLeeaakeqeaarqdhaQQLATIVEAREASVRERDAARQQLETLE 604
Cdd:COG1579      4 EDLRALLDLQELDSELDRLEHRLKELPAELAELEDEL---------------AALEARLEAAKTELEDLEKEIKRLELEI 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  605 KEKDAKLESLQQQLQA--SNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQK-A 681
Cdd:COG1579     69 EEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAElD 148

                          170       180
                   ....*....|....*....|....
gi 1958645956  682 TEREKVVQEKVQLQEQLQALEETL 705
Cdd:COG1579    149 EELAELEAELEELEAEREELAAKI 172
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1442-1699 6.04e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.41  E-value: 6.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1442 AEENRGLGERANLGRQflevELDQAREKyvqelaavRTDAETHLAEMRQEAQSTSRELEVMTAKYESAK--VKVLEERQR 1519
Cdd:COG3096    277 ANERRELSERALELRR----ELFGARRQ--------LAEEQYRLVEMARELEELSARESDLEQDYQAASdhLNLVQTALR 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1520 FQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEqasrvqqqklkafqAQGGESQQEVQCLQTQLSELQA------- 1592
Cdd:COG3096    345 QQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAE--------------ARLEAAEEEVDSLKSQLADYQQaldvqqt 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1593 ---QLSQKEQAAEHYK-------LQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQ--AGLKT 1660
Cdd:COG3096    411 raiQYQQAVQALEKARalcglpdLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiaGEVER 490

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1958645956 1661 KEAEQACRHLTAQVRSLEAQAsfyftSKVAHADQQLRDL 1699
Cdd:COG3096    491 SQAWQTARELLRRYRSQQALA-----QRLQQLRAQLAEL 524
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 338-561 6.56e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 6.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  338 AFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLK 417
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  418 QEaakLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLA---SLVADLQSSVSNLSQAKEELQQASQAqgaqL 494
Cdd:COG4942     97 AE---LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAE----L 169

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645956  495 TAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
PRK09039 PRK09039
peptidoglycan -binding protein;
526-686 8.22e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 47.27  E-value: 8.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  526 QAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQqleeaakeqeaarqdHAQQLATIVEAREASVRERDAARQQLETLEK 605
Cdd:PRK09039    41 QFFLSREISGKDSALDRLNSQIAELADLLSLERQ---------------GNQDLQDSVANLRASLSAAEAERSRLQALLA 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  606 EKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKI-------GELHACIEAAHQEQRQAQAHVTELEAQLK-AE 677
Cdd:PRK09039   106 ELAGAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQIaalrrqlAALEAALDASEKRDRESQAKIADLGRRLNvAL 185


                   ....*....
gi 1958645956  678 QQKATEREK 686
Cdd:PRK09039   186 AQRVQELNR 194
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 265-642 9.91e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 47.74  E-value: 9.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  265 KQAASPQEPSELEELRGKNESLTVRlHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHL------QQLQGA 338
Cdd:PRK10929    36 KAAKTPAQAEIVEALQSALNWLEER-KGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPNMstdaleQEILQV 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  339 FNDLIEEHSKASQEwAEKQAHLESELSTALQDKkclEEKSEILQEKISQLedraaQLQGSPAPEKGEVlgdalQLDTLKQ 418
Cdd:PRK10929   115 SSQLLEKSRQAQQE-QDRAREISDSLSQLPQQQ---TEARRQLNEIERRL-----QTLGTPNTPLAQA-----QLTALQA 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  419 EAAKLatdntelQARVETLECER----GKQE-AQLLAERghFEEEKRQLASLVADLQSSVSNLSQAK--------EELQQ 485
Cdd:PRK10929   181 ESAAL-------KALVDELELAQlsanNRQElARLRSEL--AKKRSQQLDAYLQALRNQLNSQRQREaeralestELLAE 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  486 ASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTlqeqEQAAQGLRQQVEQLSSSLKLKEQQLEeaa 565
Cdd:PRK10929   252 QSGDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQV----RQALNTLREQSQWLGVSNALGEALRA--- 324

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956  566 keqeaarqdhaqQLATIVEAREASVRERDAARQQLETLEKEKD-AKLESLQQQLQASNEARDTAQTSVTQAQ-REKAEL 642
Cdd:PRK10929   325 ------------QVARLPEMPKPQQLDTEMAQLRVQRLRYEDLlNKQPQLRQIRQADGQPLTAEQNRILDAQlRTQREL 391
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
504-900 1.08e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  504 LNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQD-----HAQQ 578
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREElekleKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  579 LATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQ 658
Cdd:COG4717    127 LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  659 EQRQAQAHVTELEAQLKaEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHA-------- 730
Cdd:COG4717    207 RLAELEEELEEAQEELE-ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgl 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  731 --------TEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLR 802
Cdd:COG4717    286 lallflllAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  803 EV-----ESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGqqqsQLAQLHACLAKALQQV 877
Cdd:COG4717    366 EEleqeiAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL----DEEELEEELEELEEEL 441

                          410       420
                   ....*....|....*....|...
gi 1958645956  878 QEKEARAQKLLDDLSALREKMAA 900
Cdd:COG4717    442 EELEEELEELREELAELEAELEQ 464
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
377-803 1.15e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  377 KSEILQEKISQLEDRAAQLQGspapEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLEceRGKQEAQLLAERGHFE 456
Cdd:COG4717     65 KPELNLKELKELEEELKEAEE----KEEEYAELQEELEELEEELEELEAELEELREELEKLE--KLLQLLPLYQELEALE 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  457 EEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQ 536
Cdd:COG4717    139 AELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  537 EQAAQGLRQQVEQLSSSLKLKEQQ------------------LEEAAKEQEAARQDHAQQLATIVE--AREASVRERDAA 596
Cdd:COG4717    219 QEELEELEEELEQLENELEAAALEerlkearlllliaaallaLLGLGGSLLSLILTIAGVLFLVLGllALLFLLLAREKA 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  597 RQQLETLEKEKDAKLESLQQQLQAsnEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKA 676
Cdd:COG4717    299 SLGKEAEELQALPALEELEEEELE--ELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALL 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  677 EQQKATEREKVVQeKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRhaTEMEAETRHLMEQREQEQKELEQEKA 756
Cdd:COG4717    377 AEAGVEDEEELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELEELEEELEELRE 453

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645956  757 ERKGLEARLQQLEEAhqaetealrHELAGATAAQHGAESEREQLLRE 803
Cdd:COG4717    454 ELAELEAELEQLEED---------GELAELLQELEELKAELRELAEE 491
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1395-1634 1.28e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1395 RAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaEENRGLGERANLGRQFLEVELDQARekyVQEL 1474
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERL-----AELEYLRAALRLWFAQRRLELLEAE---LEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1475 AAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKvkvleerqrfqeerqklTAQVEQLEvfhreqtKQVEELNKKLTE 1554
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNG-----------------GDRLEQLE-------REIERLERELEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1555 SEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEhykLQMEKAKTHYDAKKQQNQELREQLQDLEQ 1634
Cdd:COG4913    357 RERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE---EALAEAEAALRDLRRELRELEAEIASLER 433
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
543-675 1.29e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 46.58  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  543 LRQQVEQLSSSLKLKEQQLEEAAKEQEAaRQDHAQQLATIVEAREasvrERDAARQQLETLEKEKDAKLESlQQQLQASN 622
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLARLEAELGA-EAEIAAAEAQLAAAQA----QLDLAQRELERYQALYKKGAVS-QQELDEAR 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645956  623 EARDTAQTSVTQAQREKAELSQKIGELhACIEAAHQEQRQAQAHVTELEAQLK 675
Cdd:COG1566    155 AALDAAQAQLEAAQAQLAQAQAGLREE-EELAAAQAQVAQAEAALAQAELNLA 206
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
870-1296 1.39e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  870 LAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEppRAGNQESDWEEEQARPLGS 949
Cdd:COG4717     76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEL--EALEAELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  950 TQAALKAVQREAEQMGGELERLRAALMQsqgQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAelemRLQNTLNEQR 1029
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEE---LLEQLSLATEEELQDLAEELEELQQRLAELEEELE----EAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1030 VEFAALQEALTHAmtekegKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKT 1109
Cdd:COG4717    227 EELEQLENELEAA------ALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1110 EAPGPEVEALrAEISKLERQWQQQQQQVEGLTHSLESERAcrAEQDKALETLQGQLEEKARElgHNQAASASAQRELQAL 1189
Cdd:COG4717    301 GKEAEELQAL-PALEELEEEELEELLAALGLPPDLSPEEL--LELLDRIEELQELLREAEEL--EEELQLEELEQEIAAL 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1190 RAKAQDHSKAE-EEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGES--KELKRLVVAESEKSQKLEE-RLRL 1265
Cdd:COG4717    376 LAEAGVEDEEElRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEleEELEELEEELEELEEELEElREEL 455

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1958645956 1266 LQVETASSSARAAERSSALREEVQSLREEVE 1296
Cdd:COG4717    456 AELEAELEQLEEDGELAELLQELEELKAELR 486
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 306-649 1.43e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.27  E-value: 1.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  306 QMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEilQEKI 385
Cdd:TIGR00618  532 RGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSE--AEDM 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  386 SQLEDRAAQLQGSPAPEKGEVLGD--------ALQLDTLKQEAAKLATDN-TELQARVETLECERGKQEAQLLAERGHFE 456
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHlqqcsqelALKLTALHALQLTLTQERvREHALSIRVLPKELLASRQLALQKMQSEK 689

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  457 EEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQ 536
Cdd:TIGR00618  690 EQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEE 769

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  537 EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQ 616
Cdd:TIGR00618  770 VTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITH 849

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958645956  617 QLQASNEARDTAQtsvtQAQREKAELSQKIGEL 649
Cdd:TIGR00618  850 QLLKYEECSKQLA----QLTQEQAKIIQLSDKL 878
PRK11281 PRK11281
mechanosensitive channel MscK;
467-738 1.53e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.21  E-value: 1.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  467 ADLQSSVSNLSQAKeelqqasqaqgaqltaqlaSLTALNATLQQ---QDQELTSLKEQAKKEQAQMLQTLQeqeQAAQGL 543
Cdd:PRK11281    39 ADVQAQLDALNKQK-------------------LLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLA---QAPAKL 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  544 RQQVEQLSsslKLKEQQleeaakeQEAARQDHAQQLATIVEAREASVRerdaarQQLETLEKEkdakLESLQQQLQASNE 623
Cdd:PRK11281    97 RQAQAELE---ALKDDN-------DEETRETLSTLSLRQLESRLAQTL------DQLQNAQND----LAEYNSQLVSLQT 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  624 ARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQA-QAHVTELEAQLKAEQQKA----------TEREKVVQEKV 692
Cdd:PRK11281   157 QPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLlQAEQALLNAQNDLQRKSLegntqlqdllQKQRDYLTARI 236

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645956  693 Q-LQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRH------ATEMEAETR 738
Cdd:PRK11281   237 QrLEHQLQLLQEAINSKRLTLSEKTVQEAQSQDEAARIqanplvAQELEINLQ 289
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1158-1647 1.77e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.96  E-value: 1.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1158 LETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLisSLEEEVSILNRQVLE 1237
Cdd:TIGR00606  449 LEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKA--DLDRKLRKLDQEMEQ 526

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1238 KEGESKELKRLVVAESEKSQKLEE--RLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAER 1315
Cdd:TIGR00606  527 LNHHTTTRTQMEMLTKDKMDKDEQirKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQN 606

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1316 AEESGQELKAWQEKFFQKEQALsalqLEHTSTQALVSELlpakhlcqqlqaeqaaaeKRFREEIEQSKQAAGGLQAELMR 1395
Cdd:TIGR00606  607 KNHINNELESKEEQLSSYEDKL----FDVCGSQDEESDL------------------ERLKEEIEKSSKQRAMLAGATAV 664

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1396 AQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQL-SMLKKAHGLLAEENRGLGERAN-----LGRQFLEVELDQAREK 1469
Cdd:TIGR00606  665 YSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLqSKLRLAPDKLKSTESELKKKEKrrdemLGLAPGRQSIIDLKEK 744

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1470 YVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEER--QRFQEERQKLTAQVEQL--EVFHREQTKQV 1545
Cdd:TIGR00606  745 EIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTimERFQMELKDVERKIAQQaaKLQGSDLDRTV 824

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1546 EELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQ-------LSQKEQAAEHYKLQMEKAKTHYDAK 1618
Cdd:TIGR00606  825 QQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEklqigtnLQRRQQFEEQLVELSTEVQSLIREI 904

                          490       500
                   ....*....|....*....|....*....
gi 1958645956 1619 KQQNQELREQLQDLEQLQKDNKELRSETE 1647
Cdd:TIGR00606  905 KDAKEQDSPLETFLEKDQQEKEELISSKE 933
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 272-1072 1.78e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.96  E-value: 1.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  272 EPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREfanhlqqlqgAFNDLIEEHSKASQ 351
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE----------QLNDLYHNHQRTVR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  352 EWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQ--LDTLKQEAAKLATDNTE 429
Cdd:TIGR00606  316 EKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRleLDGFERGPFSERQIKNF 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  430 LQARVETLEcERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQ 509
Cdd:TIGR00606  396 HTLVIERQE-DEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  510 QQDQELT-SLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREA 588
Cdd:TIGR00606  475 ELDQELRkAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKI 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  589 SVRERDAARQQ-------------LETLEKEKDA---KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHAC 652
Cdd:TIGR00606  555 KSRHSDELTSLlgyfpnkkqledwLHSKSKEINQtrdRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  653 ------IEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQ 726
Cdd:TIGR00606  635 qdeesdLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKST 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  727 QRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHE--LAGATAAQhgaESEREQLLREV 804
Cdd:TIGR00606  715 ESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQetLLGTIMPE---EESAKVCLTDV 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  805 ESWQKRVEARQQEEARYGAMFQE----QLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQ-LHACLAKALQQVQE 879
Cdd:TIGR00606  792 TIMERFQMELKDVERKIAQQAAKlqgsDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQeQIQHLKSKTNELKS 871

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  880 KEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARplgSTQAALKAVQR 959
Cdd:TIGR00606  872 EKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNK---KAQDKVNDIKE 948

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  960 EAEQMGGELERLRAALMQSQGQQQEvrgQQEREVARLTqergqAQADLAQEKAAKAELEMRL-QNTLNEQRVEFAALQEA 1038
Cdd:TIGR00606  949 KVKNIHGYMKDIENKIQDGKDDYLK---QKETELNTVN-----AQLEECEKHQEKINEDMRLmRQDIDTQKIQERWLQDN 1020

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1958645956 1039 LTHAMTEKEGKdqELAKLREQEAAQISELKALQQ 1072
Cdd:TIGR00606 1021 LTLRKRENELK--EVEEELKQHLKEMGQMQVLQM 1052
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1276-1650 1.83e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.60  E-value: 1.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1276 RAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1355
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1356 PAKhlcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERaaqqLRAEKASYAEQLSMLK 1435
Cdd:PRK03918   242 ELE----KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK----LSEFYEEYLDELREIE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1436 KAHGLLAEENRGLGER-ANLGRQFLEV-ELDQAREKYVQELAAVRTDAETH------LAEMRQ-EAQSTSRELEVMTAKY 1506
Cdd:PRK03918   314 KRLSRLEEEINGIEERiKELEEKEERLeELKKKLKELEKRLEELEERHELYeeakakKEELERlKKRLTGLTPEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1507 ESAKvkvlEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNK----------KLTESEQAsrvqqQKLKAFQAQGGES 1576
Cdd:PRK03918   394 EELE----KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrELTEEHRK-----ELLEEYTAELKRI 464

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956 1577 QQEVQCLQTQLSELQAQLSQKEQaaehyKLQMEKAKTHYDAKKQQNQELREQLQ--DLEQLQKDNKELRSETERLG 1650
Cdd:PRK03918   465 EKELKEIEEKERKLRKELRELEK-----VLKKESELIKLKELAEQLKELEEKLKkyNLEELEKKAEEYEKLKEKLI 535
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1465-1682 1.96e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 1.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1465 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQ 1544
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1545 VEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQE 1624
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956 1625 LREQLQDLEQLQKDNKELRSeteRLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQAS 1682
Cdd:COG4942    183 LEEERAALEALKAERQKLLA---RLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
604-1140 2.03e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 2.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  604 EKEKDAKLESLQQQLQASNEARDTAQTsvtqaQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQlkaeqQKATE 683
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERAHEALED-----AREQIELLEPIRELAERYAAARERLAELEYLRAALRLW-----FAQRR 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  684 REKVVQEKVQLQEQLQALEETLKIVRGSLEEEKcRAADALKEQQRHA-----TEMEAETRHLmeqreqeQKELEQEKAER 758
Cdd:COG4913    290 LELLEAELEELRAELARLEAELERLEARLDALR-EELDELEAQIRGNggdrlEQLEREIERL-------ERELEERERRR 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  759 KGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREV-ESWQKRVEARQQEEARygamfQEQLMALKGEHG 837
Cdd:COG4913    362 ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALaEAEAALRDLRRELREL-----EAEIASLERRKS 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  838 KIGQEEQKEAGEIhgEGQTGQQQS---------QLAQLHACLAKALQQV-----------QEKEARAQKLLDD------L 891
Cdd:COG4913    437 NIPARLLALRDAL--AEALGLDEAelpfvgeliEVRPEEERWRGAIERVlggfaltllvpPEHYAAALRWVNRlhlrgrL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  892 SALREKMAATNKEVACLKA------LVLKAGEQQAAASHELKEP---------------PRA-----------GNQESDW 939
Cdd:COG4913    515 VYERVRTGLPDPERPRLDPdslagkLDFKPHPFRAWLEAELGRRfdyvcvdspeelrrhPRAitragqvkgngTRHEKDD 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  940 EEEQARP--LG-STQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQqeREVARLTQERGQAQADLAQEKAAKAE 1016
Cdd:COG4913    595 RRRIRSRyvLGfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQER--REALQRLAEYSWDEIDVASAEREIAE 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1017 LEMRLQNtLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASG 1096
Cdd:COG4913    673 LEAELER-LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1958645956 1097 DGpgsQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGL 1140
Cdd:COG4913    752 EE---RFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 441-816 2.10e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  441 RGKQEAQLLAERGHFEEeKRQLASLvadlQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQD------QE 514
Cdd:COG3096    281 RELSERALELRRELFGA-RRQLAEE----QYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEkieryqED 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  515 LTSLKEQAKkEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLK---------LKEQQLEEAAKEQEAARQDHAQQLATIVEA 585
Cdd:COG3096    356 LEELTERLE-EQEEVVEEAAEQLAEAEARLEAAEEEVDSLKsqladyqqaLDVQQTRAIQYQQAVQALEKARALCGLPDL 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  586 REASVRERDAArqqLETLEKEKDAKLESLQQQLQASNEARdtaqtsvtqAQREKA-ELSQKI-GELHAciEAAHQEQRQA 663
Cdd:COG3096    435 TPENAEDYLAA---FRAKEQQATEEVLELEQKLSVADAAR---------RQFEKAyELVCKIaGEVER--SQAWQTAREL 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  664 ------QAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQ-------ALEETLKIVRGSLEEEKcraaDALKEQQRHA 730
Cdd:COG3096    501 lrryrsQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCqrigqqlDAAEELEELLAELEAQL----EELEEQAAEA 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  731 TEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEE---AHQAETEALRHELAGATAAQHGAESEREQLLREVESW 807
Cdd:COG3096    577 VEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREqsgEALADSQEVTAAMQQLLEREREATVERDELAARKQAL 656


                   ....*....
gi 1958645956  808 QKRVEARQQ 816
Cdd:COG3096    657 ESQIERLSQ 665
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
412-820 2.11e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 2.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  412 QLDTLKQEAAKLATDNTELQARVETLEcERGKQEAQLLAERGHFEEEKRQLASLVAdLQSSVSNLSQAKEELQQasqaqg 491
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQ-LLPLYQELEALEAELAE------ 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  492 aqLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAA 571
Cdd:COG4717    144 --LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  572 RQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQA--------QREKAELS 643
Cdd:COG4717    222 LEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLlallflllAREKASLG 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  644 QKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVR------GSLEEEKC 717
Cdd:COG4717    302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEleqeiaALLAEAGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  718 RAADALKE-----QQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQA---ETEALRHELAGATAA 789
Cdd:COG4717    382 EDEEELRAaleqaEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEEleeELEELREELAELEAE 461

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1958645956  790 QHGAESEREqlLREVESWQKRVEARQQEEAR 820
Cdd:COG4717    462 LEQLEEDGE--LAELLQELEELKAELRELAE 490
mukB PRK04863
chromosome partition protein MukB;
406-732 2.17e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 2.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  406 VLGDAL---QLDTLKQEAAKLATDNTELQARVEtlECERGKQ------------------EAQLLAERGHFEEEKRQLAS 464
Cdd:PRK04863   778 LFGRAArekRIEQLRAEREELAERYATLSFDVQ--KLQRLHQafsrfigshlavafeadpEAELRQLNRRRVELERALAD 855

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  465 LVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELtslkEQAKKEQAQMLQTLQEQEQAAQGLR 544
Cdd:PRK04863   856 HESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEA----EEAKRFVQQHGNALAQLEPIVSVLQ 931

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  545 QQVEQLssslklkeQQLEEAAKEQEAARQDHAQQLATIVEAREasVRERDAARQQLETLEKEKDAKlESLQQQLQASNEA 624
Cdd:PRK04863   932 SDPEQF--------EQLKQDYQQAQQTQRDAKQQAFALTEVVQ--RRAHFSYEDAAEMLAKNSDLN-EKLRQRLEQAEQE 1000

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  625 RDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTEL--EAQLKAEQQKATEREKVVQEKVQLQEQLQALE 702
Cdd:PRK04863  1001 RTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgvPADSGAEERARARRDELHARLSANRSRRNQLE 1080

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1958645956  703 ETLKIVRGSLEE--EKCRAADALKEQQRHATE 732
Cdd:PRK04863  1081 KQLTFCEAEMDNltKKLRKLERDYHEMREQVV 1112
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1535-1651 2.17e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.39  E-value: 2.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1535 EVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQggesqqeVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTH 1614
Cdd:COG2433    384 ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQ-------VERLEAEVEELEAELEEKDERIERLERELSEARSE 456

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1958645956 1615 YDAKKQQNQELR------EQLQ-DLEQLQKDNKELRSETERLGR 1651
Cdd:COG2433    457 ERREIRKDREISrldreiERLErELEEERERIEELKRKLERLKE 500
PRK10920 PRK10920
putative uroporphyrinogen III C-methyltransferase; Provisional
 497-561 2.32e-04

putative uroporphyrinogen III C-methyltransferase; Provisional


Pssm-ID: 236795  Cd Length: 390  Bit Score: 45.86  E-value: 2.32e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956  497 QLASLTALNATLQQQdqeLTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:PRK10920    61 QAQNQTATNDALANQ---LTALQKAQESQKQELEGILKQQAKALDQANRQQAALAKQLDELQQKV 122
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1570-1679 3.11e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 45.97  E-value: 3.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1570 QAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQL-QDLEQ-LQKDNKELRSETE 1647
Cdd:PRK00409   508 KKLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLlEEAEKeAQQAIKEAKKEAD 587

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1958645956 1648 RLGREL------QQAGLKTKEAEQACRHLTAQVRSLEA 1679
Cdd:PRK00409   588 EIIKELrqlqkgGYASVKAHELIEARKRLNKANEKKEK 625
PRK11637 PRK11637
AmiB activator; Provisional
 597-826 3.18e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 45.45  E-value: 3.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  597 RQQLETLEKEKDAKLESLQQ----------QLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQah 666
Cdd:PRK11637    46 RDQLKSIQQDIAAKEKSVRQqqqqrasllaQLKKQEEAISQASRKLRETQNTLNQLNKQIDELNASIAKLEQQQAAQE-- 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  667 vTELEAQLKA--EQQKATEREKVVQ-EKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQ 743
Cdd:PRK11637   124 -RLLAAQLDAafRQGEHTGLQLILSgEESQRGERILAYFGYLNQARQETIAELKQTREELAAQKAELEEKQSQQKTLLYE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  744 REQEQKELEQEKAERK----GLEARL----QQLEEAHQAETEaLRHELAGATAAQHgAESEREQllREVEswqkRVEARQ 815
Cdd:PRK11637   203 QQAQQQKLEQARNERKktltGLESSLqkdqQQLSELRANESR-LRDSIARAEREAK-ARAEREA--REAA----RVRDKQ 274

                          250
                   ....*....|.
gi 1958645956  816 QEEARYGAMFQ 826
Cdd:PRK11637   275 KQAKRKGSTYK 285
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 480-693 3.30e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 3.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  480 KEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQ 559
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  560 QLEEAAKEQEAARQ-------DHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSV 632
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645956  633 TQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQ 693
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1504-1656 3.35e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 3.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGE--SQQEVQ 1581
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrNNKEYE 92

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956 1582 CLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLE-QLQKDNKELRSETERLGRELQQA 1656
Cdd:COG1579     93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKaELDEELAELEAELEELEAEREEL 168
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1151-1355 3.39e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1151 RAEQDKALETLQGQLEEKARELghnqaasASAQRELQALRAKAQdhskaeeewkaqVARGQQEAERKSSLISSLEEEVSI 1230
Cdd:COG3206    170 REEARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKNG------------LVDLSEEAKLLLQQLSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1231 LNRQVLEKEGESKELKRLV---------VAESEKSQKLEERLRLLQVETASSSARAAERSS---ALREEVQSLR----EE 1294
Cdd:COG3206    231 ARAELAEAEARLAALRAQLgsgpdalpeLLQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRaqlqQE 310

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645956 1295 VEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1355
Cdd:COG3206    311 AQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL 371
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 294-914 3.61e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 3.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  294 LKQCQNLKTEKNQMDRKISQLSEENGDLsfkvrefaNHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQD--- 370
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQL--------NHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpn 571

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  371 KKCLEEKSEILQEKISQLEDRAAQLQGSPApeKGEVLGDALQLDTLKQEAAKLATDNTELQArvetleCERGKQEAQLLA 450
Cdd:TIGR00606  572 KKQLEDWLHSKSKEINQTRDRLAKLNKELA--SLEQNKNHINNELESKEEQLSSYEDKLFDV------CGSQDEESDLER 643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  451 ERGHFEEEKRQLASLVADLQSSVSNLSQAKEE------LQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKK 524
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGATAVYSQFITQLTDEnqsccpVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  525 EQAQMLQTLQEQeqaaQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIV-EAREASVRERDAA-RQQLET 602
Cdd:TIGR00606  724 RRDEMLGLAPGR----QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMpEEESAKVCLTDVTiMERFQM 799

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  603 LEKEKDAKLESLQQQLQASNEARDTAQTS--VTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQK 680
Cdd:TIGR00606  800 ELKDVERKIAQQAAKLQGSDLDRTVQQVNqeKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTN 879

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  681 ATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKG 760
Cdd:TIGR00606  880 LQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKD 959

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  761 LEARLQQLEEAHQAETEalrHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEA--------------------- 819
Cdd:TIGR00606  960 IENKIQDGKDDYLKQKE---TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdnltlrkrenelkeveee 1036

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  820 ---RYGAMFQEQLMALKGEHGKIgQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALRE 896
Cdd:TIGR00606 1037 lkqHLKEMGQMQVLQMKQEHQKL-EENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTEL 1115

                          650
                   ....*....|....*...
gi 1958645956  897 KMAATNKEVACLKALVLK 914
Cdd:TIGR00606 1116 VNKDLDIYYKTLDQAIMK 1133
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 504-619 4.43e-04

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 44.11  E-value: 4.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  504 LNATLQQQDQELTSLKEQAKKEQAQmLQTLQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEqeaarQDHAQQLATIV 583
Cdd:NF038305    99 LNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLP-----EEQKEQLQQFK 171

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1958645956  584 EAREASVRERDAARQQLET--LEKEKDAKLESLQQQLQ 619
Cdd:NF038305   172 SNPQALDKFLAQQLTQIRTqaEEAEKQARLEALKSSLR 209
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
253-665 4.50e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  253 QQRIDHLALLNEKQAASPQEPSELEELRGKNESLtVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHL 332
Cdd:COG4717     91 AELQEELEELEEELEELEAELEELREELEKLEKL-LQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  333 QQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQgspapEKGEVLGDALQ 412
Cdd:COG4717    170 AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE-----NELEAAALEER 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  413 LDTLKQEAAKLATdntelqarvetlecergkqEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQakeeLQQASQAQGA 492
Cdd:COG4717    245 LKEARLLLLIAAA-------------------LLALLGLGGSLLSLILTIAGVLFLVLGLLALLFL----LLAREKASLG 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  493 QLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAAR 572
Cdd:COG4717    302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  573 QDHAQ--QLATIVEAREASVRERDAARQQLETLEKE-----KDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQK 645
Cdd:COG4717    382 EDEEElrAALEQAEEYQELKEELEELEEQLEELLGEleellEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461

                          410       420
                   ....*....|....*....|
gi 1958645956  646 IGELHACIEAAHQEQRQAQA 665
Cdd:COG4717    462 LEQLEEDGELAELLQELEEL 481
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1118-1664 4.89e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 4.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1118 ALRAEISKLERQWQQQQQQVEGLTHSLESE-RACRAEQDKALETLQGQLEEKARELghnqaaSASAQRELQALRAKAQDH 1196
Cdd:pfam15921  217 SLGSAISKILRELDTEISYLKGRIFPVEDQlEALKSESQNKIELLLQQHQDRIEQL------ISEHEVEITGLTEKASSA 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1197 SKAEEEWKAQVARGQQEAERKSSL----ISSLEEEVSILNRQVLEK----EGESKEL-KRLVVAESEKSQKLEERLRL-- 1265
Cdd:pfam15921  291 RSQANSIQSQLEIIQEQARNQNSMymrqLSDLESTVSQLRSELREAkrmyEDKIEELeKQLVLANSELTEARTERDQFsq 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1266 --------LQVETASSSARAAERS--------------------SALREEVQSLREEVEKQRVVSENLRQELASQAERAE 1317
Cdd:pfam15921  371 esgnlddqLQKLLADLHKREKELSlekeqnkrlwdrdtgnsitiDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQM 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1318 ESGQ--------------ELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSK 1383
Cdd:pfam15921  451 AAIQgkneslekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKL 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1384 QAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLE--V 1461
Cdd:pfam15921  531 QELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQefK 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1462 ELDQAREKYVQELAAVRTDAEthLAEMRQEAQSTSRELEVMTAKYEsaKVKVLEERQRFQEERQKLTAQVEQLEVFHREQ 1541
Cdd:pfam15921  611 ILKDKKDAKIRELEARVSDLE--LEKVKLVNAGSERLRAVKDIKQE--RDQLLNEVKTSRNELNSLSEDYEVLKRNFRNK 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1542 TKQVEELNKKLTESEQASRVQQQK----LKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDA 1617
Cdd:pfam15921  687 SEEMETTTNKLKMQLKSAQSELEQtrntLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHF 766

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956 1618 KKQQNQELREQLQ-----------DLEQLQKDNKELRSETERLGRELQQAGLKTKEAE 1664
Cdd:pfam15921  767 LKEEKNKLSQELStvateknkmagELEVLRSQERRLKEKVANMEVALDKASLQFAECQ 824
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 967-1309 5.02e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 5.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERgqaqadLAQEKAAKA-ELEMRLQNTLNEQRVEFAALQEALTHAMTE 1045
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQER------LRQEKEEKArEVERRRKLEEAEKARQAEMDRQAAIYAEQE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1046 K--------------EGKDQELAKLREQE-AAQISELKALQQTleelkkkekehptggargedasgdgpgsQLHTPGKTE 1110
Cdd:pfam17380  341 RmamererelerirqEERKRELERIRQEEiAMEISRMRELERL----------------------------QMERQQKNE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1111 APGPEVEALRA-EISKLERQWQQQQQQVEGLTHSLESERAcRAEQDKALEtlqgqlEEKARELGHNQAASASAQRELQAL 1189
Cdd:pfam17380  393 RVRQELEAARKvKILEEERQRKIQQQKVEMEQIRAEQEEA-RQREVRRLE------EERAREMERVRLEEQERQQQVERL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1190 RAKAQDHSKAEEEW-KAQVARGQQEAERKSSLISSLEEEVSIL-----NRQVLEKEGESK-------ELKRLVVAESEKS 1256
Cdd:pfam17380  466 RQQEEERKRKKLELeKEKRDRKRAEEQRRKILEKELEERKQAMieeerKRKLLEKEMEERqkaiyeeERRREAEEERRKQ 545

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645956 1257 QKLEERLRLLQVETASSSARAaeRSSALREEVQSLREEVEkqrvvSENLRQEL 1309
Cdd:pfam17380  546 QEMEERRRIQEQMRKATEERS--RLEAMEREREMMRQIVE-----SEKARAEY 591
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 244-1031 5.23e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 5.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  244 EKDAQIAMMQQRIDHLALLNEKQAASPQEP-----SELEELRGK--------------NESLTVRLHETLKQCQNLKTEK 304
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQSvidlqTKLQEMQMErdamadirrresqsQEDLRNQLQNTVHELEAAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  305 NQM----DRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASqewaekQAHLESELSTALQDKKCLEEKSEI 380
Cdd:pfam15921  162 EDMledsNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMS------TMHFRSLGSAISKILRELDTEISY 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  381 LQEKISQLEDRAAQLQgSPAPEKGEVLGDALQlDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKR 460
Cdd:pfam15921  236 LKGRIFPVEDQLEALK-SESQNKIELLLQQHQ-DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  461 QLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQL----ASLTALNATLQQQDQELTSLKEQAKKeqaqMLQTLQEQ 536
Cdd:pfam15921  314 MYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLvlanSELTEARTERDQFSQESGNLDDQLQK----LLADLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  537 EQAAQGLRQQVEQLSSSlKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASV-----RERDAARQQLETLEKEKD--A 609
Cdd:pfam15921  390 EKELSLEKEQNKRLWDR-DTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqgqmeRQMAAIQGKNESLEKVSSltA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQ 689
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQT 548

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  690 EKVQLQEQLQALEETLKIVRGSLEEekcrAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLe 769
Cdd:pfam15921  549 ECEALKLQMAEKDKVIEILRQQIEN----MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIREL- 623

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  770 EAHQAETEALRHELAGATAAQHGA----ESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQK 845
Cdd:pfam15921  624 EARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKS 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  846 EAGEIHGEGQTGQQQSQLAQLHACLAKALQ-QVQEKEARAQKLLDDLSALREKMAATNKEvaclkalvlkageqqaaaSH 924
Cdd:pfam15921  704 AQSELEQTRNTLKSMEGSDGHAMKVAMGMQkQITAKRGQIDALQSKIQFLEEAMTNANKE------------------KH 765

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  925 ELKEPPRAGNQEsdweeeqarplgstqaaLKAVQREAEQMGGELERLRAalmqsqgqqQEVRGQQEREVARLTQERGQAQ 1004
Cdd:pfam15921  766 FLKEEKNKLSQE-----------------LSTVATEKNKMAGELEVLRS---------QERRLKEKVANMEVALDKASLQ 819

                          810       820       830
                   ....*....|....*....|....*....|
gi 1958645956 1005 ADLAQEKAAKAELE---MRLQNTLNEQRVE 1031
Cdd:pfam15921  820 FAECQDIIQRQEQEsvrLKLQHTLDVKELQ 849
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1309-1568 5.58e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1309 LASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlqaeqaaaekrfREEIEQSKQAAGG 1388
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL---------------------ERRIAALARRIRA 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1389 LQAELMRAQRELGELGSlrqkivEQERAAQQLRAEKASYAEQLSMLKKAhgllaeenrGLGERANLGRQFLEVELDQARE 1468
Cdd:COG4942     74 LEQELAALEAELAELEK------EIAELRAELEAQKEELAELLRALYRL---------GRQPPLALLLSPEDFLDAVRRL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1469 KYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEEL 1548
Cdd:COG4942    139 QYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL 218

                          250       260
                   ....*....|....*....|
gi 1958645956 1549 NKKLTESEQASRVQQQKLKA 1568
Cdd:COG4942    219 QQEAEELEALIARLEAEAAA 238
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1374-1727 6.60e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 6.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1374 RFREEIEQSKQAAGGLQAELMRAQRELG-------------ELGSLRQKIVEQE-----------RAAQQLRAEKASYAE 1429
Cdd:COG3096    275 RHANERRELSERALELRRELFGARRQLAeeqyrlvemarelEELSARESDLEQDyqaasdhlnlvQTALRQQEKIERYQE 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1430 QLSMLKKAhgllAEENRGLGERANLGRQFLEVELDQAREKyVQELAAVRTDAETHLAEMR------QEAQSTSRELEVMT 1503
Cdd:COG3096    355 DLEELTER----LEEQEEVVEEAAEQLAEAEARLEAAEEE-VDSLKSQLADYQQALDVQQtraiqyQQAVQALEKARALC 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEQLEV------FHREQTKQVEELNKKL---TESEQASRVQQQKLKAFQAQGG 1574
Cdd:COG3096    430 GLPDLTPENAEDYLAAFRAKEQQATEEVLELEQklsvadAARRQFEKAYELVCKIageVERSQAWQTARELLRRYRSQQA 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1575 ESQQEVQcLQTQLSELQAQLSQKEQA---AEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETErlgR 1651
Cdd:COG3096    510 LAQRLQQ-LRAQLAELEQRLRQQQNAerlLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELR---Q 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1652 ELQQAGLKTKE-AEQACRHLTAQVR--SLEAQASFYFTSKV---AHADQQLRDLGKFQVATDALKSRepqvKPQLDLSID 1725
Cdd:COG3096    586 QLEQLRARIKElAARAPAWLAAQDAleRLREQSGEALADSQevtAAMQQLLEREREATVERDELAAR----KQALESQIE 661


                   ..
gi 1958645956 1726 SL 1727
Cdd:COG3096    662 RL 663
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 608-702 6.94e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 44.33  E-value: 6.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  608 DAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQ-AQAHVTELEAQLK-AEQQKATERE 685
Cdd:TIGR04320  260 QAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQtAQNNLATAQAALAnAEARLAKAKE 339

                           90
                   ....*....|....*..
gi 1958645956  686 KVVQEKVQLQEQLQALE 702
Cdd:TIGR04320  340 ALANLNADLAKKQAALD 356
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 931-1341 7.45e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 7.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  931 RAGNQESDWEEeQARPLGSTQAALKAVQREAEQM-GGELERLRAALMQSQGQQQEVRGQQERevarLTQERGQAQADLAQ 1009
Cdd:pfam15921  307 QARNQNSMYMR-QLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLANSELTEARTERDQ----FSQESGNLDDQLQK 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1010 EKA--AKAELEMRLQNTLNeQRVEFAALQEALTHAMTEKEGKDQELaklreqeaaQISELKALQQTLEELKKKEKEHPTG 1087
Cdd:pfam15921  382 LLAdlHKREKELSLEKEQN-KRLWDRDTGNSITIDHLRRELDDRNM---------EVQRLEALLKAMKSECQGQMERQMA 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1088 GARGEDASGDGPGSqlhTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSL-ESERACRAeQDKALETLQGQLE 1166
Cdd:pfam15921  452 AIQGKNESLEKVSS---LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLqEKERAIEA-TNAEITKLRSRVD 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1167 EKARELGHNQAAS---ASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1243
Cdd:pfam15921  528 LKLQELQHLKNEGdhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1244 ELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALRE----------EVQSLREEV----EKQRVVSENLRQEL 1309
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDikqerdqllnEVKTSRNELnslsEDYEVLKRNFRNKS 687

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1958645956 1310 ASQAERAEESGQELKAWQEKFFQKEQALSALQ 1341
Cdd:pfam15921  688 EEMETTTNKLKMQLKSAQSELEQTRNTLKSME 719
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 771-1059 7.57e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.66  E-value: 7.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  771 AHQAETEALRHELAGATAAQHGAESEREQLLREVESW-------QKRVEARQQEEARYGAMFQE---QLMALKGEHGKIg 840
Cdd:PRK10929    20 ATAPDEKQITQELEQAKAAKTPAQAEIVEALQSALNWleerkgsLERAKQYQQVIDNFPKLSAElrqQLNNERDEPRSV- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  841 qEEQKEAGEIhgEGQTGQQQSQLAQLhaclAKALQQVQEkeaRAQKLLDDLSALrekmaatnkevaclkalvlkaGEQQA 920
Cdd:PRK10929    99 -PPNMSTDAL--EQEILQVSSQLLEK----SRQAQQEQD---RAREISDSLSQL---------------------PQQQT 147

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  921 AASHELKEPPR----AGNQESDWEEEQARPLGSTQAALKAVQREAE--QMGG----ELERLRAALMQSQGQQ-----QEV 985
Cdd:PRK10929   148 EARRQLNEIERrlqtLGTPNTPLAQAQLTALQAESAALKALVDELElaQLSAnnrqELARLRSELAKKRSQQldaylQAL 227

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  986 RG------QQEREVARLTQERGQAQ-ADLAQEKAAKAELEMRLQNTLNEQ--RVEFAALQEALTHAMTEKegKDQELAKL 1056
Cdd:PRK10929   228 RNqlnsqrQREAERALESTELLAEQsGDLPKSIVAQFKINRELSQALNQQaqRMDLIASQQRQAASQTLQ--VRQALNTL 305


                   ...
gi 1958645956 1057 REQ 1059
Cdd:PRK10929   306 REQ 308
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1259-1602 8.19e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.50  E-value: 8.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1259 LEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSEnLRQELASQAERAEESGQELKAWQEKFFQKEQALS 1338
Cdd:pfam07888   40 LQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAE-LKEELRQSREKHEELEEKYKELSASSEELSEEKD 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1339 ALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAG-------GLQAELMRAQREL----GELGSLR 1407
Cdd:pfam07888  119 ALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKeeeaerkQLQAKLQQTEEELrslsKEFQELR 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1408 QKIVEQERAAQQLRAEKASYAEQLSMLKK---AHGLLAEENRGLGERANLGRQFLEveldqAREKYVQELAAVRTDAETH 1484
Cdd:pfam07888  199 NSLAQRDTQVLQLQDTITTLTQKLTTAHRkeaENEALLEELRSLQERLNASERKVE-----GLGEELSSMAAQRDRTQAE 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1485 LAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQ-------EERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQ 1557
Cdd:pfam07888  274 LHQARLQAAQLTLQLADASLALREGRARWAQERETLQqsaeadkDRIEKLSAELQRLEERLQEERMEREKLEVELGREKD 353

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1958645956 1558 ASRVQ----QQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAE 1602
Cdd:pfam07888  354 CNRVQlsesRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
PRK09039 PRK09039
peptidoglycan -binding protein;
599-721 9.06e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.80  E-value: 9.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  599 QLETLEKEKDAKLESLQQQLQASNEA----RDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQL 674
Cdd:PRK09039    67 DLLSLERQGNQDLQDSVANLRASLSAaeaeRSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQI 146

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645956  675 KAeqqkaterekvvqekvqLQEQLQALEETLKIVRGSLEEEKCRAAD 721
Cdd:PRK09039   147 AA-----------------LRRQLAALEAALDASEKRDRESQAKIAD 176
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1241-1684 9.68e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 9.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1241 ESKELKRLV--VAESEKSQKLEERLRLLqVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEE 1318
Cdd:TIGR00606  167 EGKALKQKFdeIFSATRYIKALETLRQV-RQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYEN 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1319 SGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAG-GLQAELMRAQ 1397
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVrEKERELVDCQ 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1398 RELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQ-FLEVELDQARE-------- 1468
Cdd:TIGR00606  326 RELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGpFSERQIKNFHTlvierqed 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1469 ------KYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEsakvKVLEERQRFQEERQKLTAQVEQLEVFHREQT 1542
Cdd:TIGR00606  406 eaktaaQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILE----KKQEELKFVIKELQQLEGSSDRILELDQELR 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1543 KQVEELNKklTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN 1622
Cdd:TIGR00606  482 KAERELSK--AEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHS 559

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956 1623 QELREQLQDL---EQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQASFY 1684
Cdd:TIGR00606  560 DELTSLLGYFpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY 624
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 461-561 9.74e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 43.95  E-value: 9.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  461 QLASLVADLQSSVSNLSQAKEELqqasQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAA 540
Cdd:TIGR04320  255 SLAALQAKLATAQADLAAAQTAL----NTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTAQNNLATAQAALANA 330

                           90       100
                   ....*....|....*....|....*
gi 1958645956  541 QG----LRQQVEQLSSSLKLKEQQL 561
Cdd:TIGR04320  331 EArlakAKEALANLNADLAKKQAAL 355
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1217-1701 9.88e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 9.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1217 KSSLISSLEE-----EVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSL 1291
Cdd:pfam12128  199 KSMIVAILEDdgvvpPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQ 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1292 REEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHtstQALVSELLPAKHLCQQLQAEQAAA 1371
Cdd:pfam12128  279 EERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQH---GAFLDADIETAAADQEQLPSWQSE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1372 EKRFREEIEQSKQAAGGLQAE-----LMRAQRELGELGSLRQKIVEQ-ERAAQQLRAEKASYAEQLSMLKKAHGLLAEEN 1445
Cdd:pfam12128  356 LENLEERLKALTGKHQDVTAKynrrrSKIKEQNNRDIAGIKDKLAKIrEARDRQLAVAEDDLQALESELREQLEAGKLEF 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1446 RGLGERANLGRQFLEVELDQA----REKYVQELAAVRTD-AETHLAEMRQEAQSTSRELEVMTAKYESAKVK-------V 1513
Cdd:pfam12128  436 NEEEYRLKSRLGELKLRLNQAtatpELLLQLENFDERIErAREEQEAANAEVERLQSELRQARKRRDQASEAlrqasrrL 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1514 LEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKlkafQAQGGESQQEVQCLQTQLSELQAQ 1593
Cdd:pfam12128  516 EERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDP----EVWDGSVGGELNLYGVKLDLKRID 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1594 LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLqdleqlqkdnKELRSETERLGRELQQAGLKTKEAEQACRHLTAQ 1673
Cdd:pfam12128  592 VPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL----------VQANGELEKASREETFARTALKNARLDLRRLFDE 661

                          490       500
                   ....*....|....*....|....*...
gi 1958645956 1674 VRSLEAQASFYFTSKVAHADQQLRDLGK 1701
Cdd:pfam12128  662 KQSEKDKKNKALAERKDSANERLNSLEA 689
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
949-1214 1.01e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  949 STQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVarLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQ 1028
Cdd:COG3206    172 EARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKL--LLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1029 RVEFAALQEALThamtekegkDQELAKLREQEAAQISELKALQQTLeelkkkekehptggargedasgdGPGSqlhtpgk 1108
Cdd:COG3206    250 GSGPDALPELLQ---------SPVIQQLRAQLAELEAELAELSARY-----------------------TPNH------- 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1109 teapgPEVEALRAEISKLERQWQQQQQQVEGlthSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQA 1188
Cdd:COG3206    291 -----PDVIALRAQIAALRAQLQQEAQRILA---SLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEV 362

                          250       260
                   ....*....|....*....|....*.
gi 1958645956 1189 LRAKAQDHSKAEEEwkAQVARGQQEA 1214
Cdd:COG3206    363 ARELYESLLQRLEE--ARLAEALTVG 386
PRK11281 PRK11281
mechanosensitive channel MscK;
1373-1677 1.02e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1373 KRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLgerA 1452
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQL---V 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1453 NLgrqfleveldQAREKYVQelaAVRTDAETHLAEMRQEAQSTSrelevmtakyESAKVKVLEERQRFQEERQKLTAQVE 1532
Cdd:PRK11281   153 SL----------QTQPERAQ---AALYANSQRLQQIRNLLKGGK----------VGGKALRPSQRVLLQAEQALLNAQND 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1533 QLevfhreqtKQVEELNKKLTESEQAsrvqQQKLKAFQAQggESQQEVQCLQTQLSELQAQLSQKeQAAEhyKLQMEKAk 1612
Cdd:PRK11281   210 LQ--------RKSLEGNTQLQDLLQK----QRDYLTARIQ--RLEHQLQLLQEAINSKRLTLSEK-TVQE--AQSQDEA- 271

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956 1613 thydAKKQQNQELREQLQDLEQLQKDnkeLRSETERLGrELQQAGLKTKE----AEQACRHLTAQVRSL 1677
Cdd:PRK11281   272 ----ARIQANPLVAQELEINLQLSQR---LLKATEKLN-TLTQQNLRVKNwldrLTQSERNIKEQISVL 332
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 341-648 1.09e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  341 DLIEEHSKASQEWAEKQAHLESELST--ALQDKKCLEEKSEIL-QEKISQLEDRA---AQLQgSPAPEKGEVLGDAlQLD 414
Cdd:NF012221  1532 DNVVATSESSQQADAVSKHAKQDDAAqnALADKERAEADRQRLeQEKQQQLAAISgsqSQLE-STDQNALETNGQA-QRD 1609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  415 TLKQEAAKLATDNTELQARVETLEcergkQEAQLLAERGhfEEEKRQLA-SLVADLQSSVSNlsqakeelqqasqaqgaq 493
Cdd:NF012221  1610 AILEESRAVTKELTTLAQGLDALD-----SQATYAGESG--DQWRNPFAgGLLDRVQEQLDD------------------ 1664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  494 ltAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQveqlssslklkeqqleeaakeqeaarq 573
Cdd:NF012221  1665 --AKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDA--------------------------- 1715

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956  574 dhaqqlativeAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARdTAQTSVTQAQREKAELSQKIGE 648
Cdd:NF012221  1716 -----------KADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
mukB PRK04863
chromosome partition protein MukB;
328-658 1.45e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  328 FANHLQQLQGAFNDL---IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQL-QGSPAPEK 403
Cdd:PRK04863   346 QQEKIERYQADLEELeerLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYqQAVQALER 425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  404 GEVLgdaLQLDTLkqEAAKLATDNTELQARVETLECERGKQEAQLL---AERGHFEEEKRQLASLVADLQSSVSNlSQAK 480
Cdd:PRK04863   426 AKQL---CGLPDL--TADNAEDWLEEFQAKEQEATEELLSLEQKLSvaqAAHSQFEQAYQLVRKIAGEVSRSEAW-DVAR 499

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  481 EELQqasqaqgaqltaQLASLTALNATLQQQDQELTSLKeqakkeqaqmlQTLQEQeQAAQGLRQQVEQLSSSLKLKEQQ 560
Cdd:PRK04863   500 ELLR------------RLREQRHLAEQLQQLRMRLSELE-----------QRLRQQ-QRAERLLAEFCKRLGKNLDDEDE 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  561 LEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEK------EKDAKLESLQQQL-------QASNEARDT 627
Cdd:PRK04863   556 LEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAArapawlAAQDALARLREQSgeefedsQDVTEYMQQ 635

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1958645956  628 AQTSVTQAQREKAELSQKIGELHACIEAAHQ 658
Cdd:PRK04863   636 LLERERELTVERDELAARKQALDEEIERLSQ 666
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1532-1710 1.46e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1532 EQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQA---------QGGESQQEVQCLQTQLSELQAQLSQKEQAAE 1602
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1603 HYKLQMEKAKTH---------YDAKKQQNQELREQLQDLEQLQKDN----KELRSETERLGRELQQaglktkEAEQACRH 1669
Cdd:COG3206    244 ALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNhpdvIALRAQIAALRAQLQQ------EAQRILAS 317

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1958645956 1670 LTAQVRSLEAQASFYfTSKVAHADQQLRDLGKFQVATDALK 1710
Cdd:COG3206    318 LEAELEALQAREASL-QAQLAQLEARLAELPELEAELRRLE 357
mukB PRK04863
chromosome partition protein MukB;
1271-1682 1.46e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1271 ASSSARAAERSSALREEVQSLREEVEKQRVvsenlrqELASQAERAEESGQELKAWQEkffqkeqALSALQLEHTST--- 1347
Cdd:PRK04863   271 AADYMRHANERRVHLEEALELRRELYTSRR-------QLAAEQYRLVEMARELAELNE-------AESDLEQDYQAAsdh 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1348 QALVSELLpakhlcqqlqaeqaaaekRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQ----LRAE 1423
Cdd:PRK04863   337 LNLVQTAL------------------RQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEevdeLKSQ 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1424 KASYAEQLSMLKKAHGLLAEENRGLgERANLGRQFLEVELDQArEKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1503
Cdd:PRK04863   399 LADYQQALDVQQTRAIQYQQAVQAL-ERAKQLCGLPDLTADNA-EDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFE 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1504 AKYESAKVKVLE-ERQRFQEERQKLTAQVEQlevfHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQc 1582
Cdd:PRK04863   477 QAYQLVRKIAGEvSRSEAWDVARELLRRLRE----QRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLD- 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1583 lqtQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRE---------- 1652
Cdd:PRK04863   552 ---DEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQsgeefedsqd 628

                          410       420       430
                   ....*....|....*....|....*....|....
gi 1958645956 1653 ----LQQAGLKTKEAEQACRHLTAQVRSLEAQAS 1682
Cdd:PRK04863   629 vteyMQQLLERERELTVERDELAARKQALDEEIE 662
MreC COG1792
Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome ...
 1613-1674 1.50e-03

Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 441397  Cd Length: 282  Bit Score: 42.95  E-value: 1.50e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958645956 1613 THYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLgRELqqagLKTKEAEQAcRHLTAQV 1674
Cdd:COG1792     68 RSLFNLREENERLKEENAELRAELQRLEELEAENARL-REL----LDLKERLDY-KFVAAEV 123
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 653-1680 1.65e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.63  E-value: 1.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  653 IEAAHQEQRQAQAHVTELEAQLKAEQQKATErekVVQEKVQLQEQLQALEETLKivrgslEEEKCRAADALKEQQRHATE 732
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQ---LCEEKNALQEQLQAETELCA------EAEEMRARLAARKQELEEIL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  733 MEAETRhlmeqREQEQKELEQEKAERKGLEARLQQLEEaHQAETEALRH--ELAGATAAQHGAESEREQLLREVESWQKR 810
Cdd:pfam01576   78 HELESR-----LEEEEERSQQLQNEKKKMQQHIQDLEE-QLDEEEAARQklQLEKVTTEAKIKKLEEDILLLEDQNSKLS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  811 VEARQQEEArygamfqeqlmaLKGEHGKIGQEEQKEAGEihgEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDD 890
Cdd:pfam01576  152 KERKLLEER------------ISEFTSNLAEEEEKAKSL---SKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGE 216

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  891 LSALREKMAATNKEVACLK-----------ALVLKAGEQQAAASHELKEPPRAGNQESDWEEEqarpLGSTQAALKAVQR 959
Cdd:pfam01576  217 STDLQEQIAELQAQIAELRaqlakkeeelqAALARLEEETAQKNNALKKIRELEAQISELQED----LESERAARNKAEK 292

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  960 EAEQMGGELERLRAAL---MQSQGQQQEVRGQQEREVARLTQergqaqadlAQEKAAKAElEMRLQNTLNEQRVEFAALQ 1036
Cdd:pfam01576  293 QRRDLGEELEALKTELedtLDTTAAQQELRSKREQEVTELKK---------ALEEETRSH-EAQLQEMRQKHTQALEELT 362

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1037 EALTHAMTEKEGKDQELAKLREQEAAQISELKALQQtleelkkkekehptggargedasgdGPGSQLHTPGKTEApgpEV 1116
Cdd:pfam01576  363 EQLEQAKRNKANLEKAKQALESENAELQAELRTLQQ-------------------------AKQDSEHKRKKLEG---QL 414

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1117 EALRAEISKLERQwqqqqqqveglthsleseracRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQD- 1195
Cdd:pfam01576  415 QELQARLSESERQ---------------------RAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDt 473

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1196 HSKAEEEWKAQVA---RGQQEAERKSSLISSLEEEVSI---LNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVE 1269
Cdd:pfam01576  474 QELLQEETRQKLNlstRLRQLEDERNSLQEQLEEEEEAkrnVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRE 553

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1270 TASSSARAAERSSA---LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQ---ELKAWQEKFF-QKEQALSALQL 1342
Cdd:pfam01576  554 LEALTQQLEEKAAAydkLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQmlaEEKAISARYAeERDRAEAEARE 633

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1343 EHTSTQALVSELLPAKhlcqQLQAEQAAAEKRFREEIEQ---SKQAAGGLQAELMRAQREL-GELGSLRQKIVEQERAAQ 1418
Cdd:pfam01576  634 KETRALSLARALEEAL----EAKEELERTNKQLRAEMEDlvsSKDDVGKNVHELERSKRALeQQVEEMKTQLEELEDELQ 709

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1419 QLRAEKASYAEQLSMLKKAH--GLLAEENRGLGERANLGRQF--LEVELDQAREKYVQELAAvRTDAETHLAEMRQ--EA 1492
Cdd:pfam01576  710 ATEDAKLRLEVNMQALKAQFerDLQARDEQGEEKRRQLVKQVreLEAELEDERKQRAQAVAA-KKKLELDLKELEAqiDA 788

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1493 QSTSRELEVMTAKYESAKVKVLE-ERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQA 1571
Cdd:pfam01576  789 ANKGREEAVKQLKKLQAQMKDLQrELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELAD 868

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1572 QGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGR 1651
Cdd:pfam01576  869 EIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNK 948

                         1050      1060      1070
                   ....*....|....*....|....*....|....*..
gi 1958645956 1652 ELQqagLKTKEAEQACRH--------LTAQVRSLEAQ 1680
Cdd:pfam01576  949 ELK---AKLQEMEGTVKSkfkssiaaLEAKIAQLEEQ 982
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1735-2018 1.70e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1735 TPCSVASKLPRTQPDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGQA--PLETSLDSLGDAFPDSGRKTRSARRR 1812
Cdd:PHA03307   179 PEETARAPSSPPAEPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1813 TTQIINITMTKKLELEEPDsaNSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRP-----TTRSSAR 1887
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSES 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1888 RSQTRTSSGAPHGRNsfymGTCQDEPeqvdDWNRIAELQQRNRvcpphlktcypleSRPALSLATITdeemktgDPRETL 1967
Cdd:PHA03307   336 SRGAAVSPGPSPSRS----PSPSRPP----PPADPSSPRKRPR-------------PSRAPSSPAAS-------AGRPTR 387

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645956 1968 RRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATscfPRPMTP 2018
Cdd:PHA03307   388 RRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR---YPLLTP 435
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1510-1655 1.87e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.70  E-value: 1.87e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  1510 KVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQK----LKAFQAQGGESQQEVQCLQT 1585
Cdd:smart00787  146 KEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCdpteLDRAKEKLKKLLQEIMIKVK 225

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645956  1586 QLSELQAQLSQKEQAAEhyklqmekakthydAKKQQNQELREQLQDLEQLQKDNKEL-RSETERLGRELQQ 1655
Cdd:smart00787  226 KLEELEEELQELESKIE--------------DLTNKKSELNTEIAEAEKKLEQCRGFtFKEIEKLKEQLKL 282
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1483-1680 2.14e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1483 THLAEMRQEAQSTSRELEVMTakyesakvKVLEERQRFQEERQKLTAQVEQLEVFHREQ-TKQVEELNKKLTESEQASRV 1561
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE--------PIRELAERYAAARERLAELEYLRAALRLWFaQRRLELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1562 QQQKLKAFQAQGGESQQEVQCLQTQLseLQAQLSQKEQAAEhyklQMEKAKTHYDAKKQQNQELREQLQDL--------E 1633
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQI--RGNGGDRLEQLER----EIERLERELEERERRRARLEALLAALglplpasaE 380

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645956 1634 QLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQ 1680
Cdd:COG4913    381 EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 614-1655 2.18e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  614 LQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIE-------AAHQEQRQAQAHVTELEAQLKAEQqkaTEREK 686
Cdd:pfam01576   45 LQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEeeeersqQLQNEKKKMQQHIQDLEEQLDEEE---AARQK 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  687 VVQEKVQLQEQLQALEETLKIV---RGSLEEEKCRAADALKEQQRHATEMEAETRHLmeqreqeQKELEQEKAERKGLEA 763
Cdd:pfam01576  122 LQLEKVTTEAKIKKLEEDILLLedqNSKLSKERKLLEERISEFTSNLAEEEEKAKSL-------SKLKNKHEAMISDLEE 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  764 RLQQLEEAHQaETEALRHELAGATAAQHGAESEREQLLREVeswqKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEE 843
Cdd:pfam01576  195 RLKKEEKGRQ-ELEKAKRKLEGESTDLQEQIAELQAQIAEL----RAQLAKKEEELQAALARLEEETAQKNNALKKIREL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  844 QkeageihgeGQTGQQQSQLAQLHACLAKALQQV----QEKEARAQKLLDDL---SALREKMAATNKEVACLKALVLKAG 916
Cdd:pfam01576  270 E---------AQISELQEDLESERAARNKAEKQRrdlgEELEALKTELEDTLdttAAQQELRSKREQEVTELKKALEEET 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  917 EQQAAASHELKEPPRAGNQESDWEEEQA-RPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVAR 995
Cdd:pfam01576  341 RSHEAQLQEMRQKHTQALEELTEQLEQAkRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQAR 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  996 LTQerGQAQADLAQEKAAKAELEMrlqntlneqrvefaalqEALTHAMTEKEGKDQELAKLREQEAAQiselkaLQQTLE 1075
Cdd:pfam01576  421 LSE--SERQRAELAEKLSKLQSEL-----------------ESVSSLLNEAEGKNIKLSKDVSSLESQ------LQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1076 ELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPgpevEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQD 1155
Cdd:pfam01576  476 LLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAK----RNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1156 KALETLQGQLEEKARELGHNQAASASAQRELQALRAkAQDHSK--AEEEWKAQVARGQQEAERKSsLISSLEEEVSILNR 1233
Cdd:pfam01576  552 RELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLV-DLDHQRqlVSNLEKKQKKFDQMLAEEKA-ISARYAEERDRAEA 629

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1234 QVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET---------ASSSARAAERSS-ALREEVQSLR---EEVEKQRV 1300
Cdd:pfam01576  630 EAREKETRALSLARALEEALEAKEELERTNKQLRAEMedlvsskddVGKNVHELERSKrALEQQVEEMKtqlEELEDELQ 709

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1301 VSEN--LRQELASQAERAEESgQELKAWQEKFFQKEQALSA----LQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR 1374
Cdd:pfam01576  710 ATEDakLRLEVNMQALKAQFE-RDLQARDEQGEEKRRQLVKqvreLEAELEDERKQRAQAVAAKKKLELDLKELEAQIDA 788

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1375 FREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIV----EQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGE 1450
Cdd:pfam01576  789 ANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILaqskESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELAD 868

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1451 RANLGRQFLEVELDQAREkyvqeLAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEER---QRFQEERQKL 1527
Cdd:pfam01576  869 EIASGASGKSALQDEKRR-----LEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERstsQKSESARQQL 943

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1528 TAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQ-QQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKL 1606
Cdd:pfam01576  944 ERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQlEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKD 1023

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645956 1607 QMEKAKTHYDAKKQQNQELREQLQDLE----QLQKDNKELRSETERLGRELQQ 1655
Cdd:pfam01576 1024 QAEKGNSRMKQLKRQLEEAEEEASRANaarrKLQRELDDATESNESMNREVST 1076
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
496-906 2.33e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 42.97  E-value: 2.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  496 AQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDH 575
Cdd:COG5278    107 ARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALAALL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  576 AQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEA 655
Cdd:COG5278    187 ALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALLAAA 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  656 AHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEA 735
Cdd:COG5278    267 LLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAAALAL 346

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  736 ETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQ 815
Cdd:COG5278    347 LAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALELAE 426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  816 QEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALR 895
Cdd:COG5278    427 ALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLALALA 506

                          410
                   ....*....|.
gi 1958645956  896 EKMAATNKEVA 906
Cdd:COG5278    507 ALLLAAAEAAL 517
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1472-1679 2.36e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 2.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1472 QELAAVRTDAEThlAEMRQEAQSTSRELE--VMTAKYESA---KVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVE 1546
Cdd:TIGR02169  198 QQLERLRREREK--AERYQALLKEKREYEgyELLKEKEALerqKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1547 ELNKKL-----------------TESEQASRVQQQKLKAFQAQggESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQME 1609
Cdd:TIGR02169  276 ELNKKIkdlgeeeqlrvkekigeLEAEIASLERSIAEKERELE--DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1610 K-------AKTHYDAKKQQ-------NQELREQLQD----LEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLT 1671
Cdd:TIGR02169  354 KlteeyaeLKEELEDLRAEleevdkeFAETRDELKDyrekLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE 433


                   ....*...
gi 1958645956 1672 AQVRSLEA 1679
Cdd:TIGR02169  434 AKINELEE 441
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 578-827 2.53e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 42.75  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  578 QLATIVEAREASVRERDAARQQLETLEkekdAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACI---E 654
Cdd:pfam19220   28 DFSQLIEPIEAILRELPQAKSRLLELE----ALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALreaE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  655 AAHQEQR----QAQAHVTELEAQLKAEqqkATEREKVVQEKVQLQEQLQALEETLKIVRGSLE---------EEKCRAAD 721
Cdd:pfam19220  104 AAKEELRielrDKTAQAEALERQLAAE---TEQNRALEEENKALREEAQAAEKALQRAEGELAtarerlallEQENRRLQ 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  722 ALKEQQ--------RHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATA----- 788
Cdd:pfam19220  181 ALSEEQaaelaeltRRLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRMKLEALTAraaat 260

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958645956  789 ----------------AQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQE 827
Cdd:pfam19220  261 eqllaearnqlrdrdeAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQE 315
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
584-1329 2.54e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 2.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  584 EAREASVRE------RDAARQQLETLEKEKDAKLESLQQQLQASNEARDTaqtsVTQAQREKAELSQKIGELHACIEAAH 657
Cdd:PRK03918   145 ESREKVVRQilglddYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEEL----IKEKEKELEEVLREINEISSELPELR 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  658 QEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLE--EEKCRAADALKEQQRHATEMEA 735
Cdd:PRK03918   221 EELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEelEEKVKELKELKEKAEEYIKLSE 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  736 ETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEahqaetealrhelagataaqhgAESEREQLLREVESWQKRVEARQ 815
Cdd:PRK03918   301 FYEEYLDELREIEKRLSRLEEEINGIEERIKELEE----------------------KEERLEELKKKLKELEKRLEELE 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  816 QEEARYgamfqEQLMALKGEHGKIGQEEQKEAGEihgegqtgqqqsqlaqlhaclaKALQQVQEKEARAQKLLDDLSALR 895
Cdd:PRK03918   359 ERHELY-----EEAKAKKEELERLKKRLTGLTPE----------------------KLEKELEELEKAKEEIEEEISKIT 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  896 EKMAATNKEVACLKalvlkageqqaAASHELKEP----PRAGNQESdwEEEQARPLGSTQAALKAVQREAEQMGGELERL 971
Cdd:PRK03918   412 ARIGELKKEIKELK-----------KAIEELKKAkgkcPVCGRELT--EEHRKELLEEYTAELKRIEKELKEIEEKERKL 478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  972 RAALmqsqgqqqevrgqQEREVARLTQERGQAQADLAQE-KAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKD 1050
Cdd:PRK03918   479 RKEL-------------RELEKVLKKESELIKLKELAEQlKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1051 QELAKLREQEAAQISELKALQQTLEELkkkekehptggargedasgdgpgSQLHTpgKTEAPGPE-VEALRAEISKLERQ 1129
Cdd:PRK03918   546 KELEKLEELKKKLAELEKKLDELEEEL-----------------------AELLK--ELEELGFEsVEELEERLKELEPF 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1130 WQQQQQQVeglthslESERACRAEQDKaLETLQGQLEEKARELGHNQAASASAQRELQALRAKAqdhskAEEEWKaqvaR 1209
Cdd:PRK03918   601 YNEYLELK-------DAEKELEREEKE-LKKLEEELDKAFEELAETEKRLEELRKELEELEKKY-----SEEEYE----E 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1210 GQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvaESEKSQKLEERLRLLQvetasssaRAAERSSALREEVQ 1289
Cdd:PRK03918   664 LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE----ELEEREKAKKELEKLE--------KALERVEELREKVK 731

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1958645956 1290 SLREEVEKQrvvSENLRQELASQ--AERAEE--SGQELKAWQEK 1329
Cdd:PRK03918   732 KYKALLKER---ALSKVGEIASEifEELTEGkySGVRVKAEENK 772
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 211-768 2.56e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  211 QFQMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLA----LLNEKQAASPQEPSELEE-------L 279
Cdd:pfam01576  102 QQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSkerkLLEERISEFTSNLAEEEEkakslskL 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  280 RGKNESLTVRLHETLKQC----QNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQ----LQGAFNDLIEEHSKASQ 351
Cdd:pfam01576  182 KNKHEAMISDLEERLKKEekgrQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKkeeeLQAALARLEEETAQKNN 261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  352 ----------EWAEKQAHLESE---LSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVlgdALQLDTLKQ 418
Cdd:pfam01576  262 alkkireleaQISELQEDLESEraaRNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEV---TELKKALEE 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  419 EAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEElqqaSQAQGAQLTAQL 498
Cdd:pfam01576  339 ETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQD----SEHKRKKLEGQL 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  499 ASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSslklkeqqleeaakeqeaarqdhaqQ 578
Cdd:pfam01576  415 QELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES-------------------------Q 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  579 LATIVEAREASVRERDAARQQLETLEKEKDakleSLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQ 658
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRLRQLEDERN----SLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEE 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  659 EQRQAQahvTELEAQLKAEQQKATEREKVVQEKVQLQEQLQ--------------ALEETLKIVRGSLEEEKCRAADALK 724
Cdd:pfam01576  546 GKKRLQ---RELEALTQQLEEKAAAYDKLEKTKNRLQQELDdllvdldhqrqlvsNLEKKQKKFDQMLAEEKAISARYAE 622

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645956  725 EQQR-HATEMEAETRHLMEQREQEQKELEQEKAER--KGLEARLQQL 768
Cdd:pfam01576  623 ERDRaEAEAREKETRALSLARALEEALEAKEELERtnKQLRAEMEDL 669
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1118-1325 2.72e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1118 ALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHS 1197
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1198 KAEEEWKAQVAR--------GQQ-------------EAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKS 1256
Cdd:COG4942     97 AELEAQKEELAEllralyrlGRQpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645956 1257 QKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKA 1325
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 790-1072 2.88e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.80  E-value: 2.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  790 QHGAESEREQLLREVESWQKRVEArqqEEARYGAMfqEQLMALKGEHGKIGQEEQKEAGEIHGEgqtgQQQSQLAQLHac 869
Cdd:pfam17380  298 QERLRQEKEEKAREVERRRKLEEA---EKARQAEM--DRQAAIYAEQERMAMERERELERIRQE----ERKRELERIR-- 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  870 lakalqqvQEKEARAQKLLDDLSALREKMAATNKEVAclkalvlkaGEQQAAASHELKEPPRAGNQESDWEEEQARPLGS 949
Cdd:pfam17380  367 --------QEEIAMEISRMRELERLQMERQQKNERVR---------QELEAARKVKILEEERQRKIQQQKVEMEQIRAEQ 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  950 TQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQ-EREVARLTQERGQAQADLAQE---KAAKAELEMRLQNTL 1025
Cdd:pfam17380  430 EEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEeERKRKKLELEKEKRDRKRAEEqrrKILEKELEERKQAMI 509

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645956 1026 NEQRvefaalqealTHAMTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:pfam17380  510 EEER----------KRKLLEKEMEERQKAIYEEERRREAEEERRKQQ 546
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 499-1005 3.10e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 42.87  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  499 ASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQ 578
Cdd:PRK10246   380 EQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQR 459

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  579 LATIVEAREaSVRERDAARQQLETL--EKEKDAKLESLQQQLQA----------SNEARDTAQT-SVTQAQREKAELSQK 645
Cdd:PRK10246   460 NAALNEMRQ-RYKEKTQQLADVKTIceQEARIKDLEAQRAQLQAgqpcplcgstSHPAVEAYQAlEPGVNQSRLDALEKE 538

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  646 IGELhacieaahqeQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEekcrAADALKE 725
Cdd:PRK10246   539 VKKL----------GEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCASLNITLQPQDD----IQPWLDA 604

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  726 QQRHATEMEAETRHLMEQREQeqkeleqekAERKGLEARLQQLEEAHQAeteALRHELAgATAAQHGAESEREQLLREVE 805
Cdd:PRK10246   605 QEEHERQLRLLSQRHELQGQI---------AAHNQQIIQYQQQIEQRQQ---QLLTALA-GYALTLPQEDEEASWLATRQ 671

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  806 SWQKRVEARQQEEARygamFQEQLMALKGEHGKIGQEEQKEAG----------EIHGE-----GQTGQQQSQLAQLHACL 870
Cdd:PRK10246   672 QEAQSWQQRQNELTA----LQNRIQQLTPLLETLPQSDDLPHSeetvaldnwrQVHEQclslhSQLQTLQQQDVLEAQRL 747

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  871 AKALQQVQ---------EKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHeLKEPPRAGNQESDWEE 941
Cdd:PRK10246   748 QKAQAQFDtalqasvfdDQQAFLAALLDEETLTQLEQLKQNLENQRQQAQTLVTQTAQALAQH-QQHRPDGLDLTVTVEQ 826

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956  942 EQARPLGSTQAALKAVQREAEqmggelerLRAALMQSQG--QQQEVRGQQEREVARLTQERGQAQA 1005
Cdd:PRK10246   827 IQQELAQLAQQLRENTTRQGE--------IRQQLKQDADnrQQQQALMQQIAQATQQVEDWGYLNS 884
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1503-1681 3.36e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.75  E-value: 3.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1503 TAKYESAKVKVLEERQRFQEerqkltaQVEQLEVFHREQTKQVEELNKkltESEQASRVQQQKLKAFQAQGGESQQEVQC 1582
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEE-------NIERLDLIIDEKRQQLERLRR---EREKAERYQALLKEKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1583 LQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLE-----QLQKDNKELRSETERLGRELQQAG 1657
Cdd:TIGR02169  235 LERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGeeeqlRVKEKIGELEAEIASLERSIAEKE 314

                          170       180
                   ....*....|....*....|....
gi 1958645956 1658 LKTKEAEQACRHLTAQVRSLEAQA 1681
Cdd:TIGR02169  315 RELEDAEERLAKLEAEIDKLLAEI 338
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
929-1350 3.40e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  929 PPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRgqQEREVARLTQERGQAQADLA 1008
Cdd:COG4717     65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--KLLQLLPLYQELEALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1009 QEKAAKAELEMR------LQNTLNEQRVEFAALQEALTHAM------TEKEGKD--QELAKLREQEAAQISELKALQQTL 1074
Cdd:COG4717    143 ELPERLEELEERleelreLEEELEELEAELAELQEELEELLeqlslaTEEELQDlaEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1075 EELKkkekehptggARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQ 1154
Cdd:COG4717    223 EELE----------EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLL 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1155 DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAE-EEWKAQVARGQQEAERKSSLISSLEEEVSILNR 1233
Cdd:COG4717    293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELEEELQLEELEQEI 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1234 QVLEKEG--ESKELKRLVVAESEKSQKLEERL-----RLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLR 1306
Cdd:COG4717    373 AALLAEAgvEDEEELRAALEQAEEYQELKEELeeleeQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELR 452

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1958645956 1307 QELASQAERAE--ESGQELKAWQEKFFQKEQALSALQLEHTSTQAL 1350
Cdd:COG4717    453 EELAELEAELEqlEEDGELAELLQELEELKAELRELAEEWAALKLA 498
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 584-823 3.47e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  584 EAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQA 663
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  664 QAHVTELEAQLKAEQ-QKATEREKVVQekvQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLME 742
Cdd:COG3883     99 GGSVSYLDVLLGSESfSDFLDRLSALS---KIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEA 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  743 QREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYG 822
Cdd:COG3883    176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAA 255


                   .
gi 1958645956  823 A 823
Cdd:COG3883    256 G 256
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
572-775 3.71e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  572 RQDHAQQLATIVEAREASVRER-DAARQQLETLEKEK-----DAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQK 645
Cdd:COG3206    169 RREEARKALEFLEEQLPELRKElEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  646 IGELHACIEAAHQEQ--RQAQAHVTELEAQLKAEQQKATEREKVVQekvQLQEQLQALEETLK----IVRGSLEEEKCRA 719
Cdd:COG3206    249 LGSGPDALPELLQSPviQQLRAQLAELEAELAELSARYTPNHPDVI---ALRAQIAALRAQLQqeaqRILASLEAELEAL 325

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645956  720 ADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAE 775
Cdd:COG3206    326 QAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
PRK12705 PRK12705
hypothetical protein; Provisional
 1465-1622 3.90e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.00  E-value: 3.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1465 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELevMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEvfhrEQTKQ 1544
Cdd:PRK12705    26 KKRQRLAKEAERILQEAQKEAEEKLEAALLEAKEL--LLRERNQQRQEARREREELQREEERLVQKEEQLD----ARAEK 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1545 VEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEV------QCLQTQLSELQAQLsqKEQAAEHYKLQMEKAKTHYDAK 1618
Cdd:PRK12705   100 LDNLENQLEEREKALSARELELEELEKQLDNELYRVagltpeQARKLLLKLLDAEL--EEEKAQRVKKIEEEADLEAERK 177


                   ....
gi 1958645956 1619 KQQN 1622
Cdd:PRK12705   178 AQNI 181
PRK11281 PRK11281
mechanosensitive channel MscK;
855-1073 4.15e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.21  E-value: 4.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  855 QTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDL-SALREKMAATNkeVACLKALVLKAGEQQAAASHELKE----- 928
Cdd:PRK11281    74 KIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNdEETRETLSTLS--LRQLESRLAQTLDQLQNAQNDLAEynsql 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  929 ------PPRAGNQESdweEEQARplgsTQ---AALKAVQREAEQMGGELERLRAALMQSQGQQQEVRgQQEREVARLTQE 999
Cdd:PRK11281   152 vslqtqPERAQAALY---ANSQR----LQqirNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQ-RKSLEGNTQLQD 223

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956 1000 RGQAQADLAQEKAAKAELEMR-LQNTLNEQRVEFA--ALQEALTHAMTEKEGKDQELAKlrEQEA-AQISElKALQQT 1073
Cdd:PRK11281   224 LLQKQRDYLTARIQRLEHQLQlLQEAINSKRLTLSekTVQEAQSQDEAARIQANPLVAQ--ELEInLQLSQ-RLLKAT 298
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1137-1721 4.43e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 4.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1137 VEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQR-------ELQALRAKAQDHSKAEEEWKAQVAR 1209
Cdd:pfam01576  358 LEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHkrkklegQLQELQARLSESERQRAELAEKLSK 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1210 GQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSAlREEVQ 1289
Cdd:pfam01576  438 LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEA-KRNVE 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1290 SLREEVEKQRVVSENLRQELASQAERAEES----GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQ 1365
Cdd:pfam01576  517 RQLSTLQAQLSDMKKKLEEDAGTLEALEEGkkrlQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLV 596

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1366 AEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGE-----------LGSLRQKIVEQERAAQQLRAEK---------- 1424
Cdd:pfam01576  597 SNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREketralslaraLEEALEAKEELERTNKQLRAEMedlvsskddv 676

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1425 ASYAEQLSMLKKAHGLLAEENRGLGER-------ANLGRQFLEVELDQAREKYVQELAAVRTDAEthlaEMRQEAQSTSR 1497
Cdd:pfam01576  677 GKNVHELERSKRALEQQVEEMKTQLEEledelqaTEDAKLRLEVNMQALKAQFERDLQARDEQGE----EKRRQLVKQVR 752

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1498 ELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQ 1577
Cdd:pfam01576  753 ELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESE 832

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1578 QEVQCLQTQLSELQAQLSQKEQA-----AEHYKLQMEKA------------KTHYDAKKQQ-NQELREQLQDLEQLQKDN 1639
Cdd:pfam01576  833 KKLKNLEAELLQLQEDLAASERArrqaqQERDELADEIAsgasgksalqdeKRRLEARIAQlEEELEEEQSNTELLNDRL 912

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1640 KELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAqasfyftsKVAHADQQLRdlGKFQVATDALKSREPQVKPQ 1719
Cdd:pfam01576  913 RKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKA--------KLQEMEGTVK--SKFKSSIAALEAKIAQLEEQ 982


                   ..
gi 1958645956 1720 LD 1721
Cdd:pfam01576  983 LE 984
mukB PRK04863
chromosome partition protein MukB;
604-1562 4.49e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 4.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  604 EKEKDAKLE---SLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAA------------HQEQ-RQAQAHV 667
Cdd:PRK04863   278 ANERRVHLEealELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAAsdhlnlvqtalrQQEKiERYQADL 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  668 TELEAQLkAEQQKATErekvvqekvQLQEQLQALEETLKIVRGSLEEEKCRAAD---ALKEQQRHATEMeaetRHLMEQR 744
Cdd:PRK04863   358 EELEERL-EEQNEVVE---------EADEQQEENEARAEAAEEEVDELKSQLADyqqALDVQQTRAIQY----QQAVQAL 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  745 EQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRH-----ELAGATAAQHgaeSEREQLLREV-------ESWQKRVE 812
Cdd:PRK04863   424 ERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSleqklSVAQAAHSQF---EQAYQLVRKIagevsrsEAWDVARE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  813 A-RQQEEARYGAmfqEQLMALKGEHGKIGQEEQkeageihgegqtgqQQSQLAQLHACLAKALQQVQEKEARAQKLLDDL 891
Cdd:PRK04863   501 LlRRLREQRHLA---EQLQQLRMRLSELEQRLR--------------QQQRAERLLAEFCKRLGKNLDDEDELEQLQEEL 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  892 SALREKmaatnkevacLKALVLKAGEQQAAASHELKEppragnQESDWEE-EQARPlgSTQAALKAVQREAEQMGGELER 970
Cdd:PRK04863   564 EARLES----------LSESVSEARERRMALRQQLEQ------LQARIQRlAARAP--AWLAAQDALARLREQSGEEFED 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  971 lRAALMQSQGQQQEvrgqQEREvarLTQERGQAQAdlaQEKAAKAELEmRLQNTLNEQRVEFAALQEALTHAMTEKEGKD 1050
Cdd:PRK04863   626 -SQDVTEYMQQLLE----RERE---LTVERDELAA---RKQALDEEIE-RLSQPGGSEDPRLNALAERFGGVLLSEIYDD 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1051 QELaklreQEAAQISELKAlqqtlEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGkteapgpEVEALRA---EISKLE 1127
Cdd:PRK04863   694 VSL-----EDAPYFSALYG-----PARHAIVVPDLSDAAEQLAGLEDCPEDLYLIEG-------DPDSFDDsvfSVEELE 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1128 RQWQQQQQQVEGLTHSLESE-RACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHskaeeewkAQ 1206
Cdd:PRK04863   757 KAVVVKIADRQWRYSRFPEVpLFGRAAREKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSH--------LA 828

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1207 VArgqqeaerkssLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQvetasssaRAAERSSALRE 1286
Cdd:PRK04863   829 VA-----------FEADPEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALN--------RLLPRLNLLAD 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1287 EvqSLREEVEkqrvvsenlrqELASQAERAEESGQELKAWQEKFFQKEQALSALQLEhtstqalvsellpakhlcqqlqa 1366
Cdd:PRK04863   890 E--TLADRVE-----------EIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSD----------------------- 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1367 eqaaaekrfREEIEQSKQAAGGLQAELMRAQRELGELGSLRQkiveqeraaqqlRAEKASYAEQLSMLKKAHGlLAEENR 1446
Cdd:PRK04863   934 ---------PEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ------------RRAHFSYEDAAEMLAKNSD-LNEKLR 991

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1447 GLGERANLGRQFLEVELDQAREKYVQELaAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAkvkvLEERQRFQEER-- 1524
Cdd:PRK04863   992 QRLEQAEQERTRAREQLRQAQAQLAQYN-QVLASLKSSYDAKRQMLQELKQELQDLGVPADSG----AEERARARRDElh 1066

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|.
gi 1958645956 1525 QKLTAQVEQLEVFHREQTKQ---VEELNKKLTESEQASRVQ 1562
Cdd:PRK04863  1067 ARLSANRSRRNQLEKQLTFCeaeMDNLTKKLRKLERDYHEM 1107
46 PHA02562
endonuclease subunit; Provisional
 494-703 5.23e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 5.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  494 LTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQ----EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQE 569
Cdd:PHA02562   179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQnkydELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALN 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  570 AARQDHAQ---QLATIveAREASVRERD----AARQQLET----LEKEKDaKLESLQQQLQASNEARDTAQ---TSVTQA 635
Cdd:PHA02562   259 KLNTAAAKiksKIEQF--QKVIKMYEKGgvcpTCTQQISEgpdrITKIKD-KLKELQHSLEKLDTAIDELEeimDEFNEQ 335

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956  636 QREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKaeqQKATEREKVVQEKVQLQEQLQALEE 703
Cdd:PHA02562   336 SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFV---DNAEELAKLQDELDKIVKTKSELVK 400
COG3899 COG3899
Predicted ATPase [General function prediction only];
761-1325 5.68e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.77  E-value: 5.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  761 LEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREV-----ESWQKRVEARQQEEARYGAMFQEQLMALKGE 835
Cdd:COG3899    688 LFELAHHLNRAGERDRAARLLLRAARRALARGAYAEALRYLERAlellpPDPEEEYRLALLLELAEALYLAGRFEEAEAL 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  836 HGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNkevacLKALVLKA 915
Cdd:COG3899    768 LERALAARALAALAALRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLGDRRLEARALF-----NLGFILHW 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  916 GEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVAR 995
Cdd:COG3899    843 LGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLA 922

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  996 LTQERGQAQADLAQEkAAKAELEMRLQNTLNEQRVEFAALQEALTHAmtekegkDQELAKLREQEAAQISELKALQQTLE 1075
Cdd:COG3899    923 AAAAAAAALALAAAA-AAAAAAALAAAAAAAALAAALALAAAAAAAA-------AAALAAAAAAAAAAAAAAAAAALEAA 994

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1076 ELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQD 1155
Cdd:COG3899    995 AAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAA 1074

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1156 KALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQV 1235
Cdd:COG3899   1075 AAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALALAALLLLAA 1154

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1236 LEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAER 1315
Cdd:COG3899   1155 LLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLALEAAALLLLLLLAALALA 1234

                          570
                   ....*....|
gi 1958645956 1316 AEESGQELKA 1325
Cdd:COG3899   1235 AALLALRLLA 1244
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1405-1630 5.92e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 5.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1405 SLRQKIVEQERAAQQLRAEKASYAEQL-------SMLKKAHGLLAEENRGLGERANLGRqfLEVELDQAREKYvQELAAV 1477
Cdd:COG3206    165 NLELRREEARKALEFLEEQLPELRKELeeaeaalEEFRQKNGLVDLSEEAKLLLQQLSE--LESQLAEARAEL-AEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1478 RTDAETHLAEMRQEAQ--STSRELEVMTAKYESAKVKVLEERQRFQEE---RQKLTAQVEQLEVFHREQTKQVeelnkkL 1552
Cdd:COG3206    242 LAALRAQLGSGPDALPelLQSPVIQQLRAQLAELEAELAELSARYTPNhpdVIALRAQIAALRAQLQQEAQRI------L 315

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956 1553 TESEQASRVQQQKLKAFQAQGGESQQEVQclqtQLSELQAQLSQKEQaaehyklQMEKAKTHYDAKKQQNQELREQLQ 1630
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLA----ELPELEAELRRLER-------EVEVARELYESLLQRLEEARLAEA 382
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1373-1652 6.60e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.65  E-value: 6.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1373 KRFREEIEQSKQAAGGLQAELMRAQRELG-ELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaeenrglgER 1451
Cdd:pfam17380  315 RRKLEEAEKARQAEMDRQAAIYAEQERMAmERERELERIRQEERKRELERIRQEEIAMEISRMREL------------ER 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1452 ANLGRQfleveldQAREKYVQELAAVRTdAETHLAEMRQEAQSTSRELEVMTAKYESAK---VKVLEER-----QRFQEE 1523
Cdd:pfam17380  383 LQMERQ-------QKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARqreVRRLEEEraremERVRLE 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1524 RQKLTAQVEQLEVFHREQTKQVEELNKkltESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAaeh 1603
Cdd:pfam17380  455 EQERQQQVERLRQQEEERKRKKLELEK---EKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKA--- 528

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1958645956 1604 ykLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKElRSETERLGRE 1652
Cdd:pfam17380  529 --IYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE-RSRLEAMERE 574
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 267-482 6.74e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 6.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  267 AASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEH 346
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  347 SKASQEWAEKQAHLESELSTAL--------------QDKKCLEEKSEILQEKISQLEDRAAQLQGspapEKGEVLGDALQ 412
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRA----DLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  413 LDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEE 482
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
NFACT_N pfam05833
NFACT N-terminal and middle domains; This family contains the N-terminal and middle domains of ...
 1515-1661 7.36e-03

NFACT N-terminal and middle domains; This family contains the N-terminal and middle domains of NFACT (NEMF, FbpA, Caliban, and Tae2) proteins from eukaryotes, archaea and bacteria. Many members of this family act in ribosome quality control (RQC), including RqcH, which are involved in the addition of a poly-Ala tail to defective translated proteins to tag them for degradation. This process is analogous to the ssrA/tmRNA bacterial system. However, some other NFACT family members, such as bacterial proteins FbpA in Listeria or PavA in Streptococcus, are exported (despite lack of a classical signal peptide) and behave as fibronectin-binding adhesins associated with virulence.


Pssm-ID: 428644 [Multi-domain]  Cd Length: 451  Bit Score: 41.07  E-value: 7.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1515 EERQRFQEERQKLTAQVEQLevFHREQtKQVEELNKKLTESEQASRVQQQK--LKAF--QAQGGESQQEVQCLQTQLSE- 1589
Cdd:pfam05833  288 AERDRVKQKRSDLEKVVQNE--LEKLE-KKLKKLEKELEEAENADEYRLYGelLTANlyQIKKGMKEVELPNYYDEGEPv 364

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645956 1590 ---LQAQLSQKEQAAEHYKLQmEKAKTHYDAKKQQNQELREQLQDLEQL--QKDNKELRSETERLGRELQQAG-LKTK 1661
Cdd:pfam05833  365 tipLDPAKSPSENAQKYFKKY-QKLKRAVEAVKEQIEETKEEIEYLESVetQLENAESLDDLEEIREELIEQGyLKKK 441
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 262-763 7.56e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.25  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  262 LNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFA------------ 329
Cdd:pfam05483  108 LQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEyereetrqvymd 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  330 --NHLQQLQGAFNDL--------IEEHSKASQEWaEKQAHLESELSTALQDKkclEEKSEIL----QEKISQLEDRAAQL 395
Cdd:pfam05483  188 lnNNIEKMILAFEELrvqaenarLEMHFKLKEDH-EKIQHLEEEYKKEINDK---EKQVSLLliqiTEKENKMKDLTFLL 263

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  396 QGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEA-------------QLLAERGHFEEEKRQL 462
Cdd:pfam05483  264 EESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKAleedlqiatkticQLTEEKEAQMEELNKA 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  463 ASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQG 542
Cdd:pfam05483  344 KAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDE 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  543 lRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETlEKEKDAKLESLQQQLQASN 622
Cdd:pfam05483  424 -KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEK-EKLKNIELTAHCDKLLLEN 501

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  623 EARDTAQTSVTQAQREKAElsqkigelhACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALE 702
Cdd:pfam05483  502 KELTQEASDMTLELKKHQE---------DIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSE 572

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645956  703 ETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEA 763
Cdd:pfam05483  573 ENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNA 633
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 508-677 8.27e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 8.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  508 LQQQDQELTSLKEQAKKEQAQmlqtLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEARe 587
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAE----LAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR- 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  588 aSVRERDAARQQLETLEKEKdaklESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHV 667
Cdd:COG1579     87 -NNKEYEALQKEIESLKRRI----SDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEEL 161

                          170
                   ....*....|
gi 1958645956  668 TELEAQLKAE 677
Cdd:COG1579    162 EAEREELAAK 171
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1151-1298 8.65e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 8.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1151 RAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQV--ARGQQEAERKSSLISSLEEEV 1228
Cdd:COG1579     26 LKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLgnVRNNKEYEALQKEIESLKRRI 105

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1229 SILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQ 1298
Cdd:COG1579    106 SDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE 175
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1513-1699 8.74e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 8.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1513 VLEERQRFQEERQkLTAQVEQLEVFH------REQTKQVEELNkkltesEQASRVQQQKLKAFQAQGGESQQEVQCLQTQ 1586
Cdd:COG4913    217 MLEEPDTFEAADA-LVEHFDDLERAHealedaREQIELLEPIR------ELAERYAAARERLAELEYLRAALRLWFAQRR 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1587 LSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDnkELRSETERLGRELQQAGLKTKEAEQA 1666
Cdd:COG4913    290 LELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLE--QLEREIERLERELEERERRRARLEAL 367

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1958645956 1667 CRHLTAQVRSLEAQasfyFTSKVAHADQQLRDL 1699
Cdd:COG4913    368 LAALGLPLPASAEE----FAALRAEAAALLEAL 396
mukB PRK04863
chromosome partition protein MukB;
430-833 9.18e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 9.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  430 LQARVETLECERGKQEAQ--LLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQltaqlASLTALNAT 507
Cdd:PRK04863   289 LELRRELYTSRRQLAAEQyrLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQ-----ADLEELEER 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  508 LQQQdqeltslkEQAKKEQAQMLQTLQEQEQAAQglrQQVEQLSSSL-----KLKEQQLEEAAKEQEAARQDHAQQLATI 582
Cdd:PRK04863   364 LEEQ--------NEVVEEADEQQEENEARAEAAE---EEVDELKSQLadyqqALDVQQTRAIQYQQAVQALERAKQLCGL 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  583 VEAREASVRERDAarqQLETLEKEKDAKLESLQQQLQASNEARD------------TAQTSVTQAQREKAELsqkigeLH 650
Cdd:PRK04863   433 PDLTADNAEDWLE---EFQAKEQEATEELLSLEQKLSVAQAAHSqfeqayqlvrkiAGEVSRSEAWDVAREL------LR 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  651 ACIEAAHQEQR--QAQAHVTELEAQLkAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEkcraadaLKEQQR 728
Cdd:PRK04863   504 RLREQRHLAEQlqQLRMRLSELEQRL-RQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLES-------LSESVS 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956  729 HATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEaHQAETEALRHELAGATAAQHGAESEREQLLREVESWQ 808
Cdd:PRK04863   576 EARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLRE-QSGEEFEDSQDVTEYMQQLLERERELTVERDELAARK 654

                          410       420
                   ....*....|....*....|....*
gi 1958645956  809 KRVEARQQEEARYGAMFQEQLMALK 833
Cdd:PRK04863   655 QALDEEIERLSQPGGSEDPRLNALA 679
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1506-1678 9.50e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.16  E-value: 9.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1506 YESAKVKVLEERQRFQEERQKLTAQVEQLEVFH---REQTKQVEELNKKLTESEQasrvQQQKLKAfqaQGGESQQEVQC 1582
Cdd:TIGR04523  171 LENELNLLEKEKLNIQKNIDKIKNKLLKLELLLsnlKKKIQKNKSLESQISELKK----QNNQLKD---NIEKKQQEINE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1583 LQTQLSELQAQLSQKEQAAEHYK-------LQMEKAKTHYDAKKQQNQELREQLQDLEQlQKD---NKELRSETERLGRE 1652
Cdd:TIGR04523  244 KTTEISNTQTQLNQLKDEQNKIKkqlsekqKELEQNNKKIKELEKQLNQLKSEISDLNN-QKEqdwNKELKSELKNQEKK 322

                          170       180
                   ....*....|....*....|....*.
gi 1958645956 1653 LQQAGLKTKEAEQACRHLTAQVRSLE 1678
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLK 348
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 1507-1661 9.58e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 40.36  E-value: 9.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1507 ESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTE------SEQASRVQQqKLKAFQAQGGESQQEV 1580
Cdd:NF033928   108 ELSELPPIPLSSDDKEIVKELKEILEDLKNDIKDYQQKADDVKKELDDfendlrEELLPQLKL-KKKLYDDNLGSDSIEE 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645956 1581 qcLQTQLSELQAQLSQKEQAAEHYKL----------------------QMEKAKTHYDAKKQQNQELREQLQDLEQLQKD 1638
Cdd:NF033928   187 --LREKIDQLEKEIEQLNKEYDDYVKlsftglaggpiglaitggifgsKAEKIRKEKNALIQEIDELQEQLKKKNALLGS 264

                          170       180
                   ....*....|....*....|...
gi 1958645956 1639 NKELRSETERLGRELQQAGLKTK 1661
Cdd:NF033928   265 LERLQTSLDDILTRMEDALPALK 287
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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